Digital Commons Network^™

Using Neutrosophic Trait Measures To Analyze Impostor Syndrome In College Students After Covid-19 Pandemic With Machine Learning, Riya Eliza Shaju, Meghana Dirisala, Muhammad Ali Najjar, Ilanthenral Kandasamy, Vasantha Kandasamy, F. Smarandache

Neutrosophic Sets and Systems

No abstract provided.

Free Vision Care Services To Be Provided At Uab's 10th Annual Gift Of Sight Event, Anna Jones

Browse All News

No abstract provided.

Study Of The Pampay Mass (Burial Of Offering) At The Summit Of The Andean Snow-Capped Mountain As An Example Of (T,I,F)-Neutrosophic Social Structure, Edgar Gutiérrez-Gómez, Ketty Marilú Moscoso-Paucarchuco, Manuel Michael Beraún-Espíritu, Fabricio Miguel Moreno-Menéndez, Rafael Jesús Fernández-Jaime, Wilfredo Fredy Paco-Huamani, Michael Raiser Vásquez-Ramírez, Jesús César Sandoval-Trigos

Neutrosophic Sets and Systems

No abstract provided.

Heptagonal Neutrosophic Topology, Kungumaraj E, Durgadevi S, Tharani N. P

Neutrosophic Sets and Systems

No abstract provided.

Analysis Of Us Airline Stocks Performance Using Latent Dirichlet Allocation (Lda), Amina Issoufou Anaroua

Beyond: Undergraduate Research Journal

Various events, such as changes in the interest rate or the hijacking of a commercial aircraft, can lead to significant shifts in airline stock performance. This study aimed to measure the impact of aviation-related news announcements on the stock performance of US airlines, focusing on different topics. The dataset included aviation news covering airlines, airports, regulations, safety, accidents, manufacturers, MRO, incidents, aviation training, general aviation, and others obtained from Aviation Voice. To uncover patterns that could explain the movements of US airline stocks, a natural language processing technique called Latent Dirichlet Allocation (LDA) was employed. The process involved text mining …

Altered Response To Toll-Like Receptor 4 Activation In Fibromyalgia: A Low-Dose, Human Experimental Endotoxemia Pilot Study, Chloe Jones, Luke Parkitny, Larissa Strath, Brant M. Wagener, Andrew Barker, Jarred Younger

APC Fund

In this pilot study, a human intravenous injection of low-dose endotoxin (lipopolysaccharide, LPS) model was used to test if fibromyalgia is associated with altered immune responses to Toll-like receptor 4 (TLR4) activation. Eight women with moderately-severe fibromyalgia and eight healthy women were administered LPS at 0.1 ng/kg in session one and 0.4 ng/kg in session two. Blood draws were collected hourly to characterize the immune response. The primary analytes of interest, leptin and fractalkine, were assayed via commercial radioimmunoassay and enzyme-linked immunosorbent assay kits, respectively. Exploratory analyses were performed on 20 secreted cytokine assays by multiplex cytokine panels, collected …

International Engagement Newsletter, November 19, 2023, University Of Northern Iowa. Office Of International Engagement.

Office of International Engagement newsletter

In this issue:

--- Announcements
--- Upcoming Events on Campus with OIE
--- Holiday Coffee Hour with President Nook
--- Immigration Updates
--- Tips from Our Director
--- Upcoming Events in the Community

Body Dysmorphia Screening Tool For Aesthetic Treatments, Brandi Harper

MSN Capstone Projects

This evidence-based project includes a discussion of Body Dysmorphic Disorder (BDD) or body image disturbance as part of pre-treatment screening in medical facilities providing appearance-altering procedures and aesthetic treatments to adult patients. The information provided serves as the foundation for endorsing the adoption of a BDD screening tool into clinical practice to increase the identification of body dysmorphia, thereby facilitating proper referral, diagnosis, and treatment to aid in patient safety and satisfaction and limit medico-legal imputations. The discussion presented here is supported by evidence-based research. It focuses on BDD prevalence and significance amongst adult patients and highlights validated screening tools …

Big Fish Populations And Ecosystem Health, Andrew N. Rowan

WellBeing News

Big fish such as sharks and tuna provide important ecosystem and tourist benefits.

Secondary Transition Resources Across New England, Mackayla O’Meara, Hannah Loverdi, Morgan Bassett, Olivia Hand

CAIEP Fall Showcase 2023

Our website focuses on creating an accessible resource for individuals approaching the transition out of secondary education who have intellectual and developmental disabilities. Within the site, there are a variety of resources for every state in New England to provide the user with a single place to find the help and resources they need instead of having to search for them on their own.

The Role Of Parenting In Developmental Trajectories Of Risk For Adolescent Substance Use: A Bioecological Systems Cascade Model, Kristine Marceau

Purdue University Libraries Open Access Publishing Fund

Parenting is a key influence and prevention target for adolescent substance use, and changes dramatically in form and function during adolescence. This theoretical synthesis reviews evidence of associations of substance use-specific parenting behaviors, dimensions, and styles with adolescent substance use, and integrates key developmental and family theories (e.g., bioecological, dynamical systems, family systems, developmental cascades) and methodological-conceptual advances to illustrate the complex role that parenting plays for the development of adolescent substance use in combination with child and contextual influences. The resulting bioecological systems cascade model centers the dynamic co-development of parenting and child influences in developmental cascades that lead …

Angiotensin Ii In Liver Transplantation (Anglt-1): Protocol Of A Randomised, Double-Blind, Placebo-Controlled Trial., Michael Bokoch, Amy Tran, Erika Brinson, Sivan Marcus, Meghana Reddy, Elizabeth Sun, Garrett Roll, Manuel Pardo, Scott Fields, Dieter Adelmann, Rishi Kothari, Matthieu Legrand

Department of Anesthesiology Faculty Papers

INTRODUCTION: Catecholamine vasopressors such as norepinephrine are the standard drugs used to maintain mean arterial pressure during liver transplantation. At high doses, catecholamines may impair organ perfusion. Angiotensin II is a peptide vasoconstrictor that may improve renal perfusion pressure and glomerular filtration rate, a haemodynamic profile that could reduce acute kidney injury. Angiotensin II is approved for vasodilatory shock but has not been rigorously evaluated for treatment of hypotension during liver transplantation. The objective is to assess the efficacy of angiotensin II as a second-line vasopressor infusion during liver transplantation. This trial will establish the efficacy of angiotensin II in …

Pakistan Study Of Premature Coronary Atherosclerosis In Young Adults (Pak-Sehat): A Prospective Longitudinal Study Protocol Investigating The Prevalence, Severity And Determinants Of Atherosclerotic Cardiovascular Disease In The Young Adult Pakistani Population, Bashir Hanif, Sana Sheikh, Ghazal Peerwani, Miguel Cainzos-Achirica, Wajiha Javed, Jaffer Bin Baqar, Zainab Samad, Faiza Bashir, Salim S. Virani, Khurram Nasir

Section of Cardiology

Introduction: Atherosclerotic cardiovascular disease (ASCVD) is a major cause of morbidity, mortality and health expenditures worldwide. Despite having higher ASCVD in the Pakistani population, data on subclinical coronary atherosclerosis in young Pakistanis remain scarce. The PAKistan Study of prEmature coronary atHerosclerosis in young AdulTs (PAK-SEHAT) aims to assess the prevalence, severity and determinants of subclinical coronary atherosclerosis among Pakistani men (35-60 years) and women (35-65 years) free of clinically symptomatic ASCVD and will assess 5-year rates of ASCVD events.
Methods and analysis: PAK-SEHAT is an ongoing prospective cohort study with 2000 participants from all provinces of Pakistan who will be …

Indoor Air Quality In Cob Buildings: In Situ Studies And Artificial Neural Network Modeling, K Touati, M-H Benzaama, Mendili Y El, Guern M Le, F Streiff, S Goodhew

School of Art, Design and Architecture

Knowledge of indoor air quality (IAQ) in cob buildings during the first few months following their delivery is of vital importance in preventing occupants’ health problems. The present research focuses on evaluating IAQ in cob buildings through a prototype built in Normandy, France. To achieve this, the prototype was equipped with a set of sensors to monitor various parameters that determine indoor and outdoor air quality. These parameters include relative humidity (RH), carbon dioxide (CO2), nitrogen dioxide (NO2), ozone (O3), particulate matter (PM1 and PM10), and volatile organic compounds (VOCs). The obtained experimental results indicate that, overall, there is good …

Postpartum Depression (Ppd) In Teenage Mothers Due To Social Determinants Of Health (Sdoh), Denise Mendez, Lindsay Gietzen

Pacific Journal of Health

The study is a qualitative research study that was done to determine if social determinants of health (SDOH) negatively impact postpartum depression (PPD) in teenage mothers. The SDOH that the study focused on were stigma, social support, and socioeconomic status. The study consisted of interviewing 5 participants. The participants are San Joaquin County residents over the age of 18 years old that have experienced being a teenage mother. The interview included questions about their mental health history, socioeconomic status and more. The findings demonstrated that SDOH negatively impacts PPD in teenage mothers. More than half of the participants shared that …

Bibliotherapy: An Expanded Role For Libraries And Librarians, Loretta Odiri Daniel (Cln)

Library Philosophy and Practice (e-journal)

A deep research into the concept of bibliotherapy revealed that it has been existence for a long time and rooted in ancient librarianship. However, the concept has moved from libraries to other corporations and organizations. This paper looks at the expanded role for libraries and librarians in bibliotherapy. Firstly, it discusses bibliotherapy or the combination of literature and healing which is designed to bring healings to library users through their interactions between relevant literature and their personalities as well as the etymology of the concept. Secondly, it expedites the types of bibliotherapy; relationship between bibliotherapy and library science; types of …

Data-Driven Decision Support Tool Co-Development With A Primary Health Care Practice Based Learning Network, Jacqueline K. Kueper, Jennifer Rayner, Sara Bhatti, Kelly Angevaare, Sandra Fitzpatrick, Paulino Lucamba, Eric Sutherland, Daniel J. Lizotte

Epidemiology and Biostatistics Publications

Background: The Alliance for Healthier Communities is a learning health system that supports Community Health Centres (CHCs) across Ontario, Canada to provide team-based primary health care to people who otherwise experience barriers to care. This case study describes the ongoing process and lessons learned from the first Alliance for Healthier Communities’ Practice Based Learning Network (PBLN) data-driven decision support tool co-development project.

Methods: We employ an iterative approach to problem identification and methods development for the decision support tool, moving between discussion sessions and case studies with CHC electronic health record (EHR) data. We summarize our work to date in …

Financial Decision-Making Among Community College Leaders, Misty Dubois Slayter

Doctoral Dissertations

The purpose of this qualitative study was to learn about financial decision-making practices of community college chancellors. This study employed an instrumental case study with three embedded cases guided by organizational decision-making theory and distributive leadership perspective. Participants were community college chancellors within the same college system. Primary data for this study included questionnaire responses, semi-structured interviews, and document analysis using constant comparative method. Chancellors deemed budget shortfalls, programs, and self-generated revenue as major decisions. Chancellors in the study used financial reports to make decisions about programs, to design organizational structure and practice, and to construct college budgets—all of which …

Exploring The Interactions Of Copper High Aspect Ratio Structures (Cuhars), A Novel Metal-Organic Biohybrid Nanocomposite, With Chondrocytes, Tasneem Khasru

Master's Theses

Osteoarthritis (OA) is a prevalent degenerative joint disorder characterized by cartilage lesions and subchondral bone destruction (1). Addressing OA is challenging due to cartilage's avascular and aneural nature, unique cellular arrangement, and dense extracellular matrix (ECM). Current pharmacological treatments are mainly symptomatic and are unable to halt disease progression or reverse cartilage damage . Surgical interventions also come with complications. Tissue-engineered grafts using biomaterials and molecular manipulation have emerged as potential treatments for cartilage regeneration. Copper-containing scaffolds have shown promise in bone and cartilage regeneration. Nanotechnology offers new avenues, with nanoparticles and nanofibers being used in tissue engineering research. However, …

Safety And Immunogenicity Of Etvax®, An Oral Inactivated Vaccine Against Enterotoxigenic Escherichia Coli Diarrhoea: A Double-Blinded, Randomized, Placebo-Controlled Trial Amongst Finnish Travellers To Benin, West Africa, Anu Kantele, Marianna Riekkinen, T Sakari Jokiranta, Sari H Pakkanen, Jukka-Pekka Pietilä, Anu Patjas, Mari Eriksson, Tamim Khawaja, Peter Klemets, Kati Marttinen, Heli Siikamäki, Anna Lundgren, Jan Holmgren, Agneta Lissmats, Nils Carlin, Ann-Mari Svennerholm

Faculty and Staff Publications

Background: No licensed human vaccines are available against enterotoxigenic Escherichia coli (ETEC), a major diarrhoeal pathogen affecting children in low- and middle-income countries and foreign travellers alike. ETVAX®, a multivalent oral whole-cell vaccine containing four inactivated ETEC strains and the heat-labile enterotoxin B subunit (LTB), has proved promising in Phase 1 and Phase 1/ 2 studies.

Methods: We conducted a Phase 2b double-blinded, randomized, placebo-controlled trial amongst Finnish travellers to Benin, West Africa. This report presents study design and safety and immunogenicity data. Volunteers aged 18-65 years were randomized 1:1 to receive ETVAX® or placebo. They visited Benin for 12 …

An International Multi-Stakeholder Delphi Survey Study On The Design Of Disease Modifying Parkinson’S Disease Trials, Marie Louise Zeissler, Kevin Mcfarthing, Karen G. Raphael, Gary Rafaloff, Richard Windle, Camille B. Carroll

Peninsula Medical School

Background: Design of disease modification (DM) trials for Parkinson’s disease (PD) is challenging. Successful delivery requires a shared understanding of priorities and practicalities. Objective: To seek stakeholder consensus on phase 3 trials’ overall goals and structure, inclusion criteria, outcome measures, and trial delivery and understand where perspectives differ. Methods: An international expert panel comprising people with Parkinson’s (PwP), care partners (CP), clinical scientists, representatives from industry, funders and regulators participated in a survey-based Delphi study. Survey items were informed by a scoping review of DM trials and PwP input. Respondents scored item agreement over 3 rounds. Scores and reasoning were …

Incidental Detection Of Fgfr3 Fusion Via Liquid Biopsy Leading To Earlier Diagnosis Of Urothelial Carcinoma, Quillan Huang, Irene Mitsiades, Heidi Dowst, Neda Zarrin-Khameh, Attiya Batool Noor, Patricia Castro, Michael E Scheurer, Guilherme Godoy, Martha P Mims, Nicholas Mitsiades

Faculty, Staff and Students Publications

The rising utilization of circulating tumor DNA (ctDNA) assays in Precision Oncology may incidentally detect genetic material from secondary sources. It is important that such findings are recognized and properly leveraged for both diagnosis and monitoring of response to treatment. Here, we report a patient in whom serial cell-free DNA (cfDNA) monitoring for his known prostate adenocarcinoma uncovered the emergence of an unexpected FGFR3-TACC3 gene fusion, a BRCA1 frameshift mutation, and other molecular abnormalities. Due to the rarity of FGFR3 fusions in prostate cancer, a workup for a second primary cancer was performed, leading to the diagnosis of an otherwise-asymptomatic …

Dietary Analysis For Hashimoto’S Thyroiditis: An Integrative Review, Evan Thompson, Alison Hultquist

Master of Science in Nursing Final Projects

Abstract

Hashimoto’s Thyroiditis (HT) is the leading cause of primary hypothyroidism in the United States. In HT, there is an infiltration by lymphocytes which leads to the production of autoantibodies against the thyroid gland. Throughout this integrative review, the aim was to evaluate the effectiveness of micronutrient supplementation and dietary management as adjunct treatments in HT. The purpose was to assist primary care providers in the development of a more holistic plan of care. Literature published within the past seven years was gathered and reviewed from PubMed, CINAHL, and Cochrane Library. Findings indicate that many patients with HT may benefit …

Association Between Microbiome And The Development Of Adverse Posttraumatic Neuropsychiatric Sequelae After Traumatic Stress Exposure, Abigail L. Zeamer, Marie-Claire Salive, Xinming An, Francesca L. Beaudoin, Stacey L. House, Jennifer S. Stevens, Donglin Zeng, Thomas C. Neylan, Gari D. Clifford, Sarah D. Linnstaedt, Scott L. Rauch, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey, Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Brittany E. Punches, Robert A. Swor, Lauren A. Hudak, Jose L. Pascual, Mark J. Seamon, Erica Harris, Claire Pearson, David A. Peak, Roland C. Merchant, Robert M. Domeier, Niels K. Rathlev, Brian J. O'Neil, Paulina Sergot, Leon D. Sanchez, Steven E. Bruce, Ronald C. Kessler, Karestan C. Koenen, Samuel A. Mclean, Vanni Bucci, John P. Haran

Einstein Health Papers

Patients exposed to trauma often experience high rates of adverse post-traumatic neuropsychiatric sequelae (APNS). The biological mechanisms promoting APNS are currently unknown, but the microbiota-gut-brain axis offers an avenue to understanding mechanisms as well as possibilities for intervention. Microbiome composition after trauma exposure has been poorly examined regarding neuropsychiatric outcomes. We aimed to determine whether the gut microbiomes of trauma-exposed emergency department patients who develop APNS have dysfunctional gut microbiome profiles and discover potential associated mechanisms. We performed metagenomic analysis on stool samples (n = 51) from a subset of adults enrolled in the Advancing Understanding of RecOvery afteR traumA …

James Alfonza Hendley

African American Funeral Programs

James_Alfonza_Hendley.pdf - Funeral program for James Alfonza Hendley

Efficacy Of Futibatinib, An Irreversible Fibroblast Growth Factor Receptor Inhibitor, In Fgfr-Altered Breast Cancer, Turcin Saridogan, Argun Akcakanat, Ming Zhao, Kurt W Evans, Erkan Yuca, Stephen Scott, Bryce P Kirby, Xiaofeng Zheng, Min Jin Ha, Huiqin Chen, Patrick K S Ng, Timothy P Diperi, Gordon B Mills, Jordi Rodon Ahnert, Senthil Damodaran, Funda Meric-Bernstam

Faculty, Staff and Student Publications

Several alterations in fibroblast growth factor receptor (FGFR) genes have been found in breast cancer; however, they have not been well characterized as therapeutic targets. Futibatinib (TAS-120; Taiho) is a novel, selective, pan-FGFR inhibitor that inhibits FGFR1-4 at nanomolar concentrations. We sought to determine futibatinib's efficacy in breast cancer models. Nine breast cancer patient-derived xenografts (PDXs) with various FGFR1-4 alterations and expression levels were treated with futibatinib. Antitumor efficacy was evaluated by change in tumor volume and time to tumor doubling. Alterations indicating sensitization to futibatinib in vivo were further characterized in vitro. FGFR gene expression between patient tumors and …

Molecular Basis Of Retinal Remodeling In A Zebrafish Model Of Retinitis Pigmentosa, Abirami Santhanam, Eyad Shihabeddin, Haichao Wei, Jiaqian Wu, John O'Brien

Faculty, Staff and Student Publications

A hallmark of inherited retinal degenerative diseases such as retinitis pigmentosa (RP) is progressive structural and functional remodeling of the remaining retinal cells as photoreceptors degenerate. Extensive remodeling of the retina stands as a barrier for the successful implementation of strategies to restore vision. To understand the molecular basis of remodeling, we performed analyses of single-cell transcriptome data from adult zebrafish retina of wild type AB strain (WT) and a P23H mutant rhodopsin transgenic model of RP with continuous degeneration and regeneration. Retinas from both female and male fish were pooled to generate each library, combining data from both sexes. …

Reflecting On Academic Freedom Through Fiction: A Theatrical Exploration Of The Blurry Contours Of The Freedom To Teach, Julie Paquin, Maude Choko

The Qualitative Report

This article aims at exploring the contribution that creative forms of research can make to the study of a little-known aspect of academic freedom in the Canadian context – academic freedom in curriculum development. It seeks to address the methodological challenge posed by research on academic freedom, that is, the fact that any academic writing on this topic necessarily draws initially, though not exclusively, from the researchers’ own experiences and perspectives. The article brings to life a fictional faculty meeting, during which questions about academic freedom in teaching are discussed. Although this meeting is the product of our imagination, its …

A Thematic Analysis Of Teacher Experiences During Active Shooter Lockdown Drills, Stephanie F. Dailey, Beth Hosek, Heather L. Walter

The Qualitative Report

Teachers are tasked with ensuring that those under their care are safe and protected, yet the lack of evidence supporting the specific needs and experiences of teachers during active school shooter lockdown drills is alarming. The current study used live-action, virtual reality (VR) technology to simulate 36 active school shooter scenarios to explore teachers' experiences related to lockdown procedures and response protocols. Using thematic analysis and structured qualitative data, 355 descriptive responses from 11 teachers across 396 scenarios were coded and analyzed for explicit and implicit themes and sub-themes. Three overarching themes—humanistic care, enacted care, and professional duty—describe how teachers …

Architecture Of The Baculovirus Nucleocapsid Revealed By Cryo-Em, Xudong Jia, Yuanzhu Gao, Yuxuan Huang, Linjun Sun, Siduo Li, Hongmei Li, Xueqing Zhang, Yinyin Li, Jian He, Wenbi Wu, Harikanth Venkannagari, Kai Yang, Matthew L Baker, Qinfen Zhang

Faculty, Staff and Student Publications

Baculovirus Autographa californica multiple nucleopolyhedrovirus (AcMNPV) has been widely used as a bioinsecticide and a protein expression vector. Despite their importance, very little is known about the structure of most baculovirus proteins. Here, we show a 3.2 Å resolution structure of helical cylindrical body of the AcMNPV nucleocapsid, composed of VP39, as well as 4.3 Å resolution structures of both the head and the base of the nucleocapsid composed of over 100 protein subunits. AcMNPV VP39 demonstrates some features of the HK97-like fold and utilizes disulfide-bonds and a set of interactions at its C-termini to mediate nucleocapsid assembly and stability. …