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Ozgene: To Advance Humanity – Inspire Curiosity, Maarit Patrick, Mike Dixon

Huntsman School of Business Teaching Scholarship Series

The case introduces the students to Ozgene, an Australian firm that experienced a dramatic reduction in lead time of their products because of implementation of Lean principles. The case can be used in undergraduate or graduate courses in operations management or supply chain management as an introduction to Lean principles. The case also encourages students to consider the challenges that make-to-order differ from those of make-to-stock and explore production design principles.

Deaconess News: Lutheran Deaconess Hospital Through The Years, 1968, V6 N1, June, Advocate Aurora Health

Historical Documents - Combined

Chicago, IL: This 1968 issue of Deaconess News, published by Lutheran Deaconess Hospital at 1138 N. Leavitt Street, Chicago, includes historical milestones, leaders throughout the years, current department news, and more.

Memo With Evangelical Hospital Systems Minority Physicians Statistics, 1984, Advocate Aurora Health

Historical Documents - Combined

Oak Lawn, IL: This November 28, 1984 memo from Evangelical Hospital Corporation includes a demographic profile of minority physicians on staff by clinical speciality. At the time EHS included Christ Community Hospital (Oak Lawn, IL), Good Samaritan Hospital (Downer's Grove, IL), and Good Shepherd Hospital (Barrington, IL).

Included is information on the broader state of minority physician representation including Chicago and areas in the United States.

Evangelical Health Systems/Evangelical Hospitals Corporation: Philosophy And Mission Implementation, 1984-1985, Advocate Aurora Health

Historical Documents - Combined

Oak Lawn, IL: This 1984/1985 document from Evangelical Health Systems/Evangelical Hospitals Corporation includes:

• Philosophy and Mission Implementation
• Appendix
• List of distribution copies
• "Medicine, Technology and Morality" article on hospital ethics committees

Advocate Health Care: Basic Facts, 1994, Advocate Aurora Health

Historical Documents - Combined

Oak Brook, IL and Park Ridge, IL: This 1994 booklet from Advocate Health Care details statistics, programs, and organizational structure on the combined organization. Included is historical information: mission, values, philosophy, branding symbols and colors, governance, regional structure, executive team, Super PHO, continuum of care service lines, and more.

New School Of Nursing Building Dedication Memo, 1965 April, Advocate Aurora Health

Historical Documents - Combined

Oak Lawn, IL: This April 29, 1965 memo details a short history of Chicago's Evangelical School of Nursing from 1911 through the 1965 move to Oak Lawn.

From 1915-1965, Evangelical graduated 817 nurses. The new building was designed by Perkins and Will at a cost of $1,113,520 plus an additional $100,000+ for furnishings. A listing of the dedication ceremony speakers includes religious and medical leaders as well as auxilliary representatives and more.

News In General : Special Issue Introducing New Logo, 1974 September, Advocate Aurora Health

Historical Documents - Combined

Park Ridge, IL: This September 1974 issue of "News in General" covers a new logo designed for Lutheran General Hospital. Past logo and symbol information from 1959 is included such as the Human Ecology star, the bible/cross/stethoscope symbol, Service League emblem, and insignia for the School of Nursing from its days at Lutheran Deaconess Hospital.

Eco-Lites Newsletter, 1961, V1 N3, December, Advocate Aurora Health

Historical Documents - Combined

Park Ridge, IL: This December 1961 newsletter, Eco-Lites, was "published by and for the employees of Lutheran General Hospital. News from departments are shared including marriages, seminars attended, comings, and goings.

Interesting items include:

• It took 7.5 minutes to process an x-ray in 1961
• A 24" television donation so "fathers waiting for their babies to be born are able to have some of their time occupied"
• A poem from the dietary department to remind staff which patients can eat off which menu (white, yellow, pink, green, and blue)

Detecting Careless Cases In Practice Tests, Steven Nydick

Chinese/English Journal of Educational Measurement and Evaluation | 教育测量与评估双语期刊

In this paper, we present a novel method for detecting careless responses in a low-stakes practice exam using machine learning models. Rather than classifying test-taker responses as careless based on model fit statistics or knowledge of truth, we built a model to predict significant changes in test scores between a practice test and an official test based on attributes of practice test items. We extracted features from practice test items using hypotheses about how careless test takers respond to items and cross-validated model performance to optimize out-of-sample predictions and reduce heteroscedasticity when predicting the closest official test. All analyses use …

Identity Transformation Through Transformative Learning: Nepali Mathematics Educators' Perspectives, Tara Paudel, Bal Chandra Luitel, Niroj Dahal

Transformations

This paper reflects the perspective of identity transformation of mathematics educators through the lens of transformative learning, foregrounded on Tara’s doctoral research journey. The process of identity transformation seeks to foster reformative skills at various levels by altering individuals and their identities. This is achieved by posing questions about the past that challenge deeply ingrained assumptions, beliefs, values, and perspectives. Therefore, this paper’s focus is on how transformative learning facilitates a shift in identity. This issue signifies a theoretical void that warrants further investigation. Consequently, this paper examines identity transformations through the theories and lens of transformative learning. In doing …

A Survey Of Internal Medicine Residents Comparing Virtual Academic Half Day To Traditional Academic Half Day Model, Basil George Verghese, Salem N. Thabet

Advances in Clinical Medical Research and Healthcare Delivery

Introduction. Resident educational activities vary from institute to institute, with daily noon conferences or weekly academic half-day (AHD) models where dedicated protected time is available for resident teaching. The COVID-19 pandemic limited in-person educational activities, forcing residency programs to move toward virtual options, including the academic half-day (AHD). This survey-based cohort study aimed to understand residents' perception of virtual versus in-person AHD for educational activities during residency.

Methods. The survey was emailed to 72 Internal Medicine residency program residents at our institute during the first week of March, 2022. The responses were analyzed using descriptive statistics, Pearson's chi-square test, …

Colocolic Fistula: A Rare Consequential Presentation Of Cecal Mucinous Adenocarcinoma, Jessica Rutyna, Paige Stratton, Rutwik Pradeep Sharma, Anthony V. Baratta Jr

Advances in Clinical Medical Research and Healthcare Delivery

Colorectal cancer (CRC) is the second most common cause of cancer death in the United States. Relative to a 5-year survival rate, CRC patients diagnosed with localized disease accrue a 90% survival rate while those diagnosed with distant-stage disease maintain 14% survival. Mucinous adenocarcinoma (MAC) is a unique subtype of CRC characterized by the presence of extracellular mucin occupying 50% of tumor expansion. Fistula complications of colonic malignancy have rarely been reported and more commonly occur as complications of diverticulitis. Colocolic fistulae are atypical consequences of colon cancer, which have been rarely reported. We wish to report a unique case …

Metastatic Breast Cancer Found During Colon Cancer Screening, Rutwik Pradeep Sharma, Tausif Syed, Meenal Sharma, Jay Bapaye, Ahmed Shehadah, Alexander T. Kusnik, Ali Jaan, Richard Alweis, Andrej Strapko

Advances in Clinical Medical Research and Healthcare Delivery

No abstract provided.

Bouveret's Syndrome: A Case Report And Review Of The Literature, Sheza Malik, Hajra Khan, Jay Bapaye, Asim Mushtaq

Advances in Clinical Medical Research and Healthcare Delivery

Bouveret syndrome is an exceedingly rare complication of cholelithiasis, characterized by gastric or intestinal obstruction due to the impaction of one or more gallstones in the proximal gastrointestinal tract. We present a case of an elderly woman with multiple comorbidities who presented with gastric outlet obstruction caused by a cholecystogastric fistula. The management and treatment of Bouveret syndrome present a challenge, as endoscopic retrieval is the first-line treatment strategy, but it is rarely successful. Most patients ultimately require surgery as was seen in our case

Defying The Vicious Cycle: An Intriguing Case Of Brash Syndrome, Ahmed Shehadah, Himal Kharel, Pulkit Gandhi

Advances in Clinical Medical Research and Healthcare Delivery

BRASH Syndrome is a rare and life-threatening condition marked by the combination of bradycardia, renal failure, atrioventricular (AV) nodal blockade, shock, and hyperkalemia. This case report presents a 79-year-old female with acute kidney injury, hyperkalemia, and severe bradycardia without typical EKG changes associated with hyperkalemia. The aim of this article is to provide a comprehensive overview of BRASH syndrome, including its clinical manifestations, underlying pathophysiology, diagnostic approaches, and management strategies. The patient's presentation, laboratory findings, and response to treatment support the diagnosis of BRASH syndrome. The syndrome's pathogenesis involves a vicious cycle of bradycardia, renal failure, AV nodal blockade, and …

A Case Of A Retroperitoneal Leiomyoma During Total Laparoscopic Hysterectomy, Bruce Lee, Mohamad Mahmoud

Advances in Clinical Medical Research and Healthcare Delivery

Retroperitoneal leiomyomas are rare clinical entities and poses clinical and therapeutic challenges to the benign gynecologist. We present the case of a 51 year-old gravida 2 para 2 with symptomatic leiomyomas undergoing definitive surgical management with total laparoscopic hysterectomy. Intraoperatively, a retroperitoneal mass in the pelvic side was identified, excised, and removed from the abdominal cavity without complications. Final pathology confirmed a leiomyoma.

Alopecia Areata Following Covid-19 Vaccine, Andrew Takla, Omar Alali, Mostafa Zaalouk, Soon-Il Song

Advances in Clinical Medical Research and Healthcare Delivery

No abstract provided.

The Prevalence And Impact Of Obesity On The Outcomes Of Patients Undergoing Transcatheter Mitral Valve Repair Using Mitraclip - A National Inpatient Sample Analysis 2016 To 2020., Garba Rimamskep Shamaki, Favour Markson, Osarenren Idemudia, Andrew Murphy, Tamunoinemi Bob-Manuel, Akanimo Antia, David Corteville

Advances in Clinical Medical Research and Healthcare Delivery

Background: Low Body Mass Index (BMI) is associated with poor outcomes in patients who undergo various cardiac interventions. Studies on patients with elevated BMI have produced mixed results. Our study aims to evaluate the impact of obesity on the in-hospital outcomes of patients undergoing transcatheter mitral valve repair using MitraClip in the United States.

Methods: The National Inpatient Sample (NIS) database (2016-2020) was analyzed to identify patients who underwent transcatheter mitral valve repair using MitraClip. Patients less than 18 years, with protein-energy malnutrition and rapid weight loss, were excluded. Our final study population was classified into Obese (BMI ≥ 30 …

Kounis Syndrome – Anaphylaxis-Induced Acute Coronary Syndrome, Austin T. Thacker Do, Brachman Herzig Oms, Brendan Robinson Do, Ahad Anjum Do

Advances in Clinical Medical Research and Healthcare Delivery

Kounis syndrome is an underdiagnosed condition in which anaphylaxis triggers vasospastic acute coronary syndrome, either with or without underlying coronary artery disease. The prevalence of this syndrome among hospitalized patients for allergic/hypersensitivity/anaphylactic reactions in the United States is 1.1%, with a 7% rate of all-cause inpatient mortality. This article presents an anaphylaxis-induced acute coronary syndrome case in a patient with underlying coronary artery disease. The pathophysiological mechanism of anaphylactic-induced acute coronary syndrome involves the inflammatory mediators of type I hypersensitivity reactions.

Race/Socioeconomic Status And Covid-19: A Narrative Review, Olubunmi Oladunjoye, Akinwale Akingbule, Adebola Omogunwa, Logan Lawson, Anthony Donato

Advances in Clinical Medical Research and Healthcare Delivery

Background: COVID-19 infection has resulted in more than 620 million infections and 6.6 million deaths. Since the pandemic, many articles have been published on socioeconomic and racial disparities in COVID-19 infection and its outcomes. This article aims to review the impact of race and socioeconomic status on COVID-19 infection and vice versa.

Findings: Most studies showed an increase in COVID infections and hospitalizations in communities of color, with some showing higher mortality rates while others did not. Social determinants, including insurance and care access, food security, housing security appear to have worsened over the same period for these …

Minoca - A Rarity Of It's Own And The Importance Of Cardiac Mri, Abdullah A. Orakzai, Deeptanshu Jain Md, Muhammad Osama, Syeda Sarah Raza, Soon-Il Song

Advances in Clinical Medical Research and Healthcare Delivery

Myocardial infarction with non-obstructive coronary arteries (MINOCA) disease is a diagnostic dilemma with clinical evidence of acute myocardial infarction (AMI) with normal coronary arteries. MINOCA is a complex issue; the management of the patients needs to be focused on identifying the core problem. Cardiac magnetic resonance (CMR) imaging is a non-invasive diagnostic tool that can play an important role in enabling clinicians to build a differential diagnosis in patients with MINOCA and also identify other non-ischemic aetiologies of myocardial injury. We present a challenging case of a patient with MINOCA with MI in small proximal septal artery distribution revealed on …

A Case Of A Prominent Coumadin Ridge Poses A Diagnostic Dilemma, Astha Prasai, Krupa Shingada, Omar Alali, Nawid Latifi, Mohammad Abu Sheikha, Jian Shan

Advances in Clinical Medical Research and Healthcare Delivery

Introduction:

Coumadin ridge, also known as warfarin ridge, is an embryological remnant in the form of a muscular ridge in the left atrium. We present a case of a middle-aged gentleman with prominent Coumadin ridge.

Case:

49 year old male with history of pulmonary embolism (PE) (on Xarelto), attention deficit hyperactivity disorder (ADHD), prior polysubstance use, currently everyday smoker presented to the emergency department with history of shortness of breath and productive cough for 8 weeks. Initially he was treated with doxycycline for bronchitis and later with azithromycin for pneumonia as outpatient. He did not have chest pain, palpitations or …

Prevalence And Predictors Of Venous Stenosis Following First Transvenous Cardiac Implantable Electronic Device Implantation., ​Qayoom Yousuf, Aamir Rashid, Imran Hafeez, Hilal Rather, Ishrath Syed, Altaf Hussain Mir, Suheel Ahmad Mir, Ajaz ​ Lone

Journal of the Saudi Heart Association

Objectives: Very few studies have been done on Venous stenosis following the first transvenous cardiac device implantation. We aimed to assess the prevalence and predictors of Venous stenosis/Occlusion following the first transvenous cardiac device implantation with venous angiography at one year of follow-up. Methods: This study was a single-center prospective, observational study. Demographic, clinical, procedural, and device data was collected. All patients underwent a preimplant contrast and repeated venography at twelve months to look for upper limb venous anatomy, obstruction, or collaterals. Results: A total of 146 patients were included in the final analysis. 60 (41 %) patients developed some …

Continuous Intrathecal Saline Infusion For Treating Refractory Spontaneous Intracranial Hypotension: A Case Report, Po-Fan Chiu, Yu-Hsiang Lin, Hui-Shan Lu, I-Han Hsiao, Hung-Lin Lin

BioMedicine

Spontaneous intracranial hypotension (SIH) is a poorly understood condition that presents with a wide variety of symptoms, ranging from mild headaches to coma. It is typically caused by continuous spontaneous leakage of spinal cerebrospinal fluid (CSF), resulting in orthostatic headaches. However, the appropriate management of refractory SIH remains unclear. A 50-year-old man presented with orthostatic headache followed by a rapid decline in mental status. The imaging findings were consistent with the diagnosis of SIH, with bilateral cerebral subdural hematomas and abnormal fluid collection in the posterior epidural space from the T2 to T12 levels. Computed tomography myelography of the whole …

Celastrol Restricts Experimental Periodontitis Related Alveolar Bone Loss By Suppressing Inflammatory Cytokine Response, Ahmet Altin, Meltem Zi̇hni̇ Korkmaz, Mehtap Atak, Tolga Mercantepe, Hülya Kiliç Yilmaz

BioMedicine

Introduction: Periodontitis is a common chronic inflammatory disease characterized by the destruction of the supporting structures of the teeth. The host defense mechanisms are responsible for inflamatuar and destructive reactions in periodontitis. Celastrol is one of the most promising components of the plant in Eastern and Southern China that has a long history of use in traditional medicine for the treatment of inflammatory conditions. Aim: The aim of this animal study was to inspect the preventive or restrictive effects of celastrol on periodontitis-related inflammatory host response and alveolar bone loss. Methods: 24 male Sprague Dawley rats were randomly assigned into …

Hematological Biomarkers Of Troponin, Neutrophil-To-Lymphocyte Ratio, And Monocyte-Tolymphocyte Ratio Serve As Effective Predictive Indicators Of High-Risk Mortality In Acute, Bryan Gervais De Liyis, Angela Faustine Ciaves, Marwa Humaira Intizam, Pierre Joshua Jusuf, I Made Junior Rina Artha

BioMedicine

Background: Assessing high-risk mortality in acute coronary syndrome (ACS) patients, encompassing ST-Elevation Myocardial Infarction (STEMI), Non-ST-Elevation Myocardial Infarction (NSTEMI), and Unstable Angina Pectoris (UAP), is crucial. However, the prognostic significance of hematological parameters in predicting high-risk mortality in ACS patients remains uncertain despite advancements in ACS research. Aim: The aim was to investigate prognostic significance of hematological parameters troponin, Creatine Kinase-MB (CKMB), Neutrophil-to-Lymphocyte Ratio (NLR), Platelet-to-Lymphocyte Ratio (PLR), Monocyte-to-Lymphocyte Ratio (MLR), Basophil-to-Lymphocyte Ratio (BLR), and Eosinophil-to-Lymphocyte Ratio (ELR) levels in predicting high-risk mortality in ACS patients. Methods: In this retrospective observational study, data from medical records of 115 patients with …

Efficacy Of Hmj-38, A New Quinazolinone Analogue, Against The Gemcitabine-Resistant Mia-Paca-2 Pancreatic Cancer Cells, Mann-Jen Hour, Fuu‑ Jen Tsai, I-Lu Lai, Je-Wei Tsao, Jo-Hua Chiang, Yu-Jen Chiu, Hsing-Fang Lu, Yu‑ Ning Juan, Jai-Sing Yang, Shih-Chang Tsai

BioMedicine

Gemcitabine is frequently utilized to treat pancreatic cancer. The purpose of our study was to create a gemcitabine-resistant MIA-PaCa-2 pancreatic cancer cell line (MIAGR100) and to evaluate the anti-pancreatic cancer efficacy of HMJ-38, a new quinazolinone analogue. Compared to their parental counterparts, MIA-PaCa-2, established MIA-GR100 cells were less sensitive to gemcitabine. MIA-GR100 cell viability was not affected by 10, 50, or 100 nM gemcitabine concentrations. HMJ-38 reduced MIA-GR100 cell growth and induced autophagy and apoptosis. When stained with monodansylcadaverine (MDC), acridine orange (AO), and terminal deoxynucleotide transferase dUTP nick end labeling (TUNEL), MIA-GR100 cells shrunk, punctured their membranes, and produced …

Chemical Composition, Mineral Profile, Anti-Bacterial, And Wound Healing Properties Of Snail Slime Of Helix Aspersa Müller, Marouane Aouji, Amine Rkhaila, Bouchra Bouhaddioui, Malak Zirari, Hala Harifi, Youness Taboz, Lalla Aicha Lrhorfi, Rachid Bengueddour

BioMedicine

Mucus is a substance made by snails that serves a variety of purposes and is increasingly employed in the medical and cosmetic industries. It includes bioactive compounds with a range of biological characteristics that could be useful in the treatment of particular issues. This study assessed the wound-healing efficiency, antibacterial activity, chemical and mineral composition of Helix aspersa Müller slime. Inductively Coupled Argon Plasma Atomic Emission Spectrometry (ICP-OES) was used for mineral analysis, while Gas chromatography coupled to mass spectrometry (GC-MS) analysis was used for chemical characterization. The findings showed that the H. aspersa Müller slime had inhibitory activity on …

Mutation Patterns Of Integrase Gene Affect Antiretroviral Resistance In Various Non-B Subtypes Of Human Immunodeficiency Virus Type-1 And Their Implications For Patients’ Therapy, Fauzia Andrini Djojosugito, Arfianti Arfianti, Rudi , Wisaksana, Agnes Rengga Indrati

BioMedicine

Although primary integrase strand transfer inhibitor resistance mutations are currently uncommon, the increasing use of integrase strand transfer inhibitor as a key component of the first, second and third-line antiretroviral regimens suggests that the prevalence of integrase drug resistance mutations will likely increase. The rise of several polymorphic mutations and natural polymorphisms also affects the level of susceptibility of human immunodeficiency virus (HIV) type-1 to integrase strand transfer inhibitor. The considerable variability among the various subtypes of human immunodeficiency virus type-1 may contribute to differences in integrase mutations associated with integrase strand transfer inhibitors. Notably, non-B subtypes of HIV type-1 …

Ideas Weren’T Enough: The Strategies Behind Paul Simon’S Run For President, 1987-88, Robert Hartley

The Simon Review (Occasional Papers of the Paul Simon Public Policy Institute)

Ideas. That word best describes the fifty-two years Paul Simon spent as a public person, journalist, politician, author, and head of a policy institute. His ideas flowed nonstop at the local community level, state legislature, and in Congress.

When Simon opened his 1987-88 campaign for the Democratic presidential nomination, he did what he always did: fed the public his ideas for solving the ills of the federal government and setting a national direction. As he stated in his announcement, “I dream of an America at work in a world at peace.” Straight stuff. But would voters outside familiar ground in …