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Effects Of Interactive Video Games (Nintendo Wii™) On Older Adults With Cognitive Impairment, Krista Antonio, Sarah Kelly, Kayla Livingston, Bailey Stewart Dec 2023

Effects Of Interactive Video Games (Nintendo Wii™) On Older Adults With Cognitive Impairment, Krista Antonio, Sarah Kelly, Kayla Livingston, Bailey Stewart

Occupational Therapy Student Research

The population being served includes the clients at Triple R adult day program in Sacramento, CA. These clients are older adults and all present with a form of memory loss. Currently, health management, specifically physical activity, and social participation are affected in the program as there are limitations to exercise routines that are appropriate for the clients as well as lack of engagement from all clients. We believe that all of the residents are affected by this issue at the facility and would benefit from the use of technology to enhance these areas of needs in the specific occupations. Within …


Tactus Therapy: Mobile At For Aphasia, Francis Gonzales, Robert Swayze, David Vong Dec 2023

Tactus Therapy: Mobile At For Aphasia, Francis Gonzales, Robert Swayze, David Vong

Occupational Therapy Student Research

Pacific Speech, Hearing and Language Center

  • Adults with communicative impairments and disorders (language, hearing, speech).
  • Aphasia apps focus on communication by improving vocabulary, memory, reasoning, attention, differentiation, and organization of concepts, presented as pictures, text, or audio (Galletta & Barrett, 2014).
  • Aphasia can affect populations such as those who have autism, TMI, stroke, and encephalitis (Galletta & Barrett, 2014).


Closing Gap In Digital Divide Of The Vulnerable Women In The Community Via Assistive Technology: The Chromebook, Deanne Nguyen, Brian Rogers, Hazel Yang Dec 2023

Closing Gap In Digital Divide Of The Vulnerable Women In The Community Via Assistive Technology: The Chromebook, Deanne Nguyen, Brian Rogers, Hazel Yang

Occupational Therapy Student Research

  • Aims to address the gap in digital division by providing low-income individuals with essential computer skills.
  • These individuals are currently facing health challenges due to economic constraints, limited access to healthcare services, and overall lack of familiarity in digital literacy.
  • At Wellspring Women’s Center, nearly 200 individuals are affected by this issue.
  • The Chromebook could be delivered in a flexible model such as in-person workshops, online tutorials, and 1:1 mentoring.
  • This approach ensures accessibility and empowerment of the participants to develop essential digital literacy skills to promote independence in their own health management.
  • The Chromebook can open gates to enhancing …


Meristem (Monday): Checklists, Maribel Gutierrez, Josephine Hernandez, Benjamin Magallon, Margerie Vinoya Dec 2023

Meristem (Monday): Checklists, Maribel Gutierrez, Josephine Hernandez, Benjamin Magallon, Margerie Vinoya

Occupational Therapy Student Research

Occupational therapy (OT) students from the University of the Pacific assessed needs in various classrooms at Meristem, a college program for individuals in the neurodivergent population to expand life skills of independence. OT students identified the use of checklists, a low-cost assistive device in creating structure of expected tasks in the classroom. The goal of the checklist is to reduce dependency on instructors for reminders and prompts, and promote resilience, autonomy, and enhanced participation in the classroom. The checklist can be personalized for each instructor to fit the needs of their classroom expectations.


Supporting Mental Health Of Wellspring Women’S Center, Lio Inumerable, Sophia Kohgadai, Christie Ledezma, Taylor Sanders Dec 2023

Supporting Mental Health Of Wellspring Women’S Center, Lio Inumerable, Sophia Kohgadai, Christie Ledezma, Taylor Sanders

Occupational Therapy Student Research

Wellspring Women’s Center located in Sacramento, CA

  • Serves vulnerable women and their children.
  • Safe space for community gathering and various basic needs including:
    • Nutritious meals
    • Safety net items
    • Children’s area for learning
    • Women’s Wellness Program
      • Counseling
      • Case management
      • Advocacy
      • Art therapy


Assistive Technology: Video Modeling, Abigail Waisner, Molly Mcdavid, Haley Morris, Luis Perez Dec 2023

Assistive Technology: Video Modeling, Abigail Waisner, Molly Mcdavid, Haley Morris, Luis Perez

Occupational Therapy Student Research

Population and Site:

  • Meristem is an educational program serving young adults who have autism or other neurodiversity (Who we are, 2023).The program promotes vocational and independent living skills through classes, community experiences, and dorm life that address physical, social, and cognitive skills. Students living in dorms are given additional opportunities to develop independent living skills such as cooking, cleaning, organization, community mobility, and social participation.
Project Goal:
  • Our goal as a group was toidentify ways to support students in the acquisition of independent living skills. The ideal assistive technology for this population would be a technology that is easily accessible,portable, …


Winter Commencement, 2023, Marshall University Dec 2023

Winter Commencement, 2023, Marshall University

Marshall University Commencement

Program for the One Hundred Eighty-Eighth Commencement of Marshall University, Saturday, December 9 2023 held at the Mountain Health Arena in Huntington, West Virginia.


Beyond N-Dopants For Organic Semiconductors: Use Of Bibenzo[D]Imidazoles In Uv-Promoted Dehalogenation Reactions Of Organic Halides, Kan Tang, Megan R. Brown, Chad Risko, Melissa K. Gish, Garry Rumbles, Phuc H. Pham, Oana R. Luca, Stephen Barlow, Seth R. Marder Dec 2023

Beyond N-Dopants For Organic Semiconductors: Use Of Bibenzo[D]Imidazoles In Uv-Promoted Dehalogenation Reactions Of Organic Halides, Kan Tang, Megan R. Brown, Chad Risko, Melissa K. Gish, Garry Rumbles, Phuc H. Pham, Oana R. Luca, Stephen Barlow, Seth R. Marder

UK CARES Faculty Publications

2,2’-Bis(4-dimethylaminophenyl)- and 2,2'-dicyclohexyl-1,1',3,3'-tetramethyl-2,2',3,3'-tetrahydro-2,2'-bibenzo[d]imidazole ((N-DMBI)2 and (Cyc-DMBI)2) are quite strong reductants with effective potentials of ca. −2 V vs ferrocenium/ferrocene, yet are relatively stable to air due to the coupling of redox and bond-breaking processes. Here, we examine their use in accomplishing electron transfer-induced bond-cleavage reactions, specifically dehalogenations. The dimers reduce halides that have reduction potentials less cathodic than ca. −2 V vs ferrocenium/ferrocene, especially under UV photoexcitation (using a 365 nm LED). In the case of benzyl halides, the products are bibenzyl derivatives, whereas aryl halides are reduced to the corresponding arenes. The potentials of the halides that can be …


Expflow: A Graphical User Interface For Automated Reproducible Electrochemistry, Rebekah Duke, Siamak Mahmoudi, Aman Preet Kaur, Vinayak Bhat, Ian C. Dingle, Nathan C. Stumme, Scott K. Shaw, David L. Eaton, Asmund Vego, Chad Risko Dec 2023

Expflow: A Graphical User Interface For Automated Reproducible Electrochemistry, Rebekah Duke, Siamak Mahmoudi, Aman Preet Kaur, Vinayak Bhat, Ian C. Dingle, Nathan C. Stumme, Scott K. Shaw, David L. Eaton, Asmund Vego, Chad Risko

UK CARES Faculty Publications

Reproducible data and results underpin the credibility and integrity of research findings across the sciences. However, experiments and measurements conducted across laboratories, or by different researchers, are often hindered by incomplete or inaccessible procedural data. Additionally, the time and resources needed to manually perform repeat experiments and analyses limit the scale at which experiments can be reproduced. Both improved methods for recording and sharing experimental procedures in machine- readable formats and efforts towards automation can be beneficial to circumvent these issues. Here we report the development of ExpFlow, a data collection, sharing, and reporting software currently customized for electrochemical experiments. …


The Relationship Of Insufficient Resources To Leadership Burnout In Rural Nonprofit Organizations, Keilee Webb Dec 2023

The Relationship Of Insufficient Resources To Leadership Burnout In Rural Nonprofit Organizations, Keilee Webb

Honors College Theses

The purpose of this thesis is to describe and analyze the relationship between the lack of resources in nonprofit organizations and burnout. In this literature review, the aim is to explore various resources affecting nonprofit entities as they relate to organizational capacity. These specific resources will be reviewed and discussed to understand how closely related those resources are to burnout. Additionally, the implications of nonprofit employee and volunteer burnout will be analyzed. Within the literature review, the research indicates nonprofits in rural United States are more likely to encounter a deficit in connections to resources than their urban counterparts. This …


Pollutant Forecasting Using Neural Network-Based Temporal Models, Richard Pike Dec 2023

Pollutant Forecasting Using Neural Network-Based Temporal Models, Richard Pike

Masters Theses & Specialist Projects

The Jing-Jin-Ji region of China is a highly industrialized and populated area of the country. Its periodic high pollution and smog includes particles smaller than 2.5 μm, known as PM2.5, linked to many respiratory and cardiovascular illnesses. PM2.5 concentration around Jing-Jin-Ji has exceeded China’s urban air quality safety threshold for over 20% of all days in 2017 through 2020.

The quantity of ground weather stations that measure the concentrations of these pollutants, and their valuable data, is unfortunately small. By employing many machine learning strategies, many researchers have focused on interpolating finer spatial grids of PM2.5, or hindcasting PM2.5. However, …


Perceptions Of The Farm Bill Among Nonmetropolitan Nebraskans, Rebecca J. Vogt, Heather Akin, Cheryl A. Burkhart-Kriesel, Bradley D. Lubben, L. J. Mcelravy, Timothy Meyer, Steven A. Schulz Dec 2023

Perceptions Of The Farm Bill Among Nonmetropolitan Nebraskans, Rebecca J. Vogt, Heather Akin, Cheryl A. Burkhart-Kriesel, Bradley D. Lubben, L. J. Mcelravy, Timothy Meyer, Steven A. Schulz

Nebraska Rural Poll

The federal legislation known as the farm bill encompasses all things related to agriculture and food. This includes not only farm income safety net and conservation programs that typically come to mind when thinking about the farm bill, but also domestic food assistance programs (like SNAP), rural development (providing funding for items like broadband service, utilities, and housing programs) as well as programs that are focused on specific producers and crops. Given the variety of programs it entails, how familiar are rural Nebraskans with the farm bill and federal agricultural policy? Do rural Nebraskans support federal spending on the various …


Association Between Microbiome And The Development Of Adverse Posttraumatic Neuropsychiatric Sequelae After Traumatic Stress Exposure, Abigail L. Zeamer, Marie Claire Salive, Xinming An, Francesca L. Beaudoin, Stacey L. House, Jennifer S. Stevens, Donglin Zeng, Thomas C. Neylan, Gari D. Clifford, Sarah D. Linnstaedt, Scott L. Rauch, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey, Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Brittany E. Punches, Robert A. Swor, Lauren A. Hudak, Jose L. Pascual, Mark J. Seamon, Erica Harris, Claire Pearson, David A. Peak, Roland C. Merchant, Robert M. Domeier, Niels K. Rathlev, Brian J. O’Neil, Paulina Sergot, Leon D. Sanchez, Steven E. Bruce Dec 2023

Association Between Microbiome And The Development Of Adverse Posttraumatic Neuropsychiatric Sequelae After Traumatic Stress Exposure, Abigail L. Zeamer, Marie Claire Salive, Xinming An, Francesca L. Beaudoin, Stacey L. House, Jennifer S. Stevens, Donglin Zeng, Thomas C. Neylan, Gari D. Clifford, Sarah D. Linnstaedt, Scott L. Rauch, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey, Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Brittany E. Punches, Robert A. Swor, Lauren A. Hudak, Jose L. Pascual, Mark J. Seamon, Erica Harris, Claire Pearson, David A. Peak, Roland C. Merchant, Robert M. Domeier, Niels K. Rathlev, Brian J. O’Neil, Paulina Sergot, Leon D. Sanchez, Steven E. Bruce

Psychology Faculty Works

Patients exposed to trauma often experience high rates of adverse post-traumatic neuropsychiatric sequelae (APNS). The biological mechanisms promoting APNS are currently unknown, but the microbiota-gut-brain axis offers an avenue to understanding mechanisms as well as possibilities for intervention. Microbiome composition after trauma exposure has been poorly examined regarding neuropsychiatric outcomes. We aimed to determine whether the gut microbiomes of trauma-exposed emergency department patients who develop APNS have dysfunctional gut microbiome profiles and discover potential associated mechanisms. We performed metagenomic analysis on stool samples (n = 51) from a subset of adults enrolled in the Advancing Understanding of RecOvery afteR traumA …


Neuroimaging-Based Classification Of Ptsd Using Data-Driven Computational Approaches: A Multisite Big Data Study From The Enigma-Pgc Ptsd Consortium, Xi Zhu, Yoojean Kim, Orren Ravid, Xiaofu He, Benjamin Suarez-Jimenez, Sigal Zilcha-Mano, Amit Lazarov, Seonjoo Lee, Chadi G. Abdallah, Michael Angstadt, Christopher L. Averill, C. Lexi Baird, Lee A. Baugh, Jennifer U. Blackford, Jessica Bomyea, Steven E. Bruce, Richard A. Bryant, Zhihong Cao, Kyle Choi, Josh Cisler, Andrew S. Cotton, Judith K. Daniels, Nicholas D. Davenport, Richard J. Davidson, Michael D. Debellis, Emily L. Dennis, Maria Densmore, Terri Deroon-Cassini, Seth G. Disner, Wissam El Hage, Amit Etkin, Negar Fani Dec 2023

Neuroimaging-Based Classification Of Ptsd Using Data-Driven Computational Approaches: A Multisite Big Data Study From The Enigma-Pgc Ptsd Consortium, Xi Zhu, Yoojean Kim, Orren Ravid, Xiaofu He, Benjamin Suarez-Jimenez, Sigal Zilcha-Mano, Amit Lazarov, Seonjoo Lee, Chadi G. Abdallah, Michael Angstadt, Christopher L. Averill, C. Lexi Baird, Lee A. Baugh, Jennifer U. Blackford, Jessica Bomyea, Steven E. Bruce, Richard A. Bryant, Zhihong Cao, Kyle Choi, Josh Cisler, Andrew S. Cotton, Judith K. Daniels, Nicholas D. Davenport, Richard J. Davidson, Michael D. Debellis, Emily L. Dennis, Maria Densmore, Terri Deroon-Cassini, Seth G. Disner, Wissam El Hage, Amit Etkin, Negar Fani

Psychology Faculty Works

Background: Recent advances in data-driven computational approaches have been helpful in devising tools to objectively diagnose psychiatric disorders. However, current machine learning studies limited to small homogeneous samples, different methodologies, and different imaging collection protocols, limit the ability to directly compare and generalize their results. Here we aimed to classify individuals with PTSD versus controls and assess the generalizability using a large heterogeneous brain datasets from the ENIGMA-PGC PTSD Working group. Methods: We analyzed brain MRI data from 3,477 structural-MRI; 2,495 resting state-fMRI; and 1,952 diffusion-MRI. First, we identified the brain features that best distinguish individuals with PTSD from controls …


Use Of Serial Smartphone-Based Assessments To Characterize Diverse Neuropsychiatric Symptom Trajectories In A Large Trauma Survivor Cohort, Francesca L. Beaudoin, Xinming An, Archana Basu, Yinyao Ji, Mochuan Liu, Ronald C. Kessler, Robert F. Doughtery, Donglin Zeng, Kenneth A. Bollen, Stacey L. House, Jennifer S. Stevens, Thomas C. Neylan, Gari D. Clifford, Tanja Jovanovic, Sarah D. Linnstaedt, Laura T. Germine, Scott L. Rauch, John P. Haran, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey, Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Brittany E. Punches, Michael C. Kurz, Robert A. Swor, Vishnu P. Murty, Meghan E. Mcgrath, Lauren A. Hudak, Jose L. Pascual, Elizabeth M. Datner Dec 2023

Use Of Serial Smartphone-Based Assessments To Characterize Diverse Neuropsychiatric Symptom Trajectories In A Large Trauma Survivor Cohort, Francesca L. Beaudoin, Xinming An, Archana Basu, Yinyao Ji, Mochuan Liu, Ronald C. Kessler, Robert F. Doughtery, Donglin Zeng, Kenneth A. Bollen, Stacey L. House, Jennifer S. Stevens, Thomas C. Neylan, Gari D. Clifford, Tanja Jovanovic, Sarah D. Linnstaedt, Laura T. Germine, Scott L. Rauch, John P. Haran, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey, Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Brittany E. Punches, Michael C. Kurz, Robert A. Swor, Vishnu P. Murty, Meghan E. Mcgrath, Lauren A. Hudak, Jose L. Pascual, Elizabeth M. Datner

Psychology Faculty Works

The authors sought to characterize adverse posttraumatic neuropsychiatric sequelae (APNS) symptom trajectories across ten symptom domains (pain, depression, sleep, nightmares, avoidance, re-experiencing, anxiety, hyperarousal, somatic, and mental/fatigue symptoms) in a large, diverse, understudied sample of motor vehicle collision (MVC) survivors. More than two thousand MVC survivors were enrolled in the emergency department (ED) and completed a rotating battery of brief smartphone-based surveys over a 2-month period. Measurement models developed from survey item responses were used in latent growth curve/mixture modeling to characterize homogeneous symptom trajectories. Associations between individual trajectories and pre-trauma and peritraumatic characteristics and traditional outcomes were compared, along …


Culture In The Spice Industry, Karla Moreno Dec 2023

Culture In The Spice Industry, Karla Moreno

Management Undergraduate Honors Theses

Culture impacts business in a variety of ways. None the less in the spice industry, culture plays an essential role in its supply chain stages and market. When marketing the spices to the consumers, it is important to note how culture can affect the way the spices are packaged and marketed to their targeted consumers.


Navigating The Mind: Mental Health Struggles Among College Students Throughout And Post Pandemic, Megan Lempke Dec 2023

Navigating The Mind: Mental Health Struggles Among College Students Throughout And Post Pandemic, Megan Lempke

Honors Projects in Psychology

Several studies have reported that the coronavirus pandemic has contributed to the rise in stress, anxiety, and depression levels among college students. This has left mental health professionals at a loss and overwhelmed with the number of new cases during this time. Research has been conducted and has found that these levels have risen because of the pandemic, the lock down, personal factors, and their new learning environment which includes academics as well. Most of the research that has been done focuses on before the pandemic and during the pandemic, but not much research has been conducted for after the …


Successful Treatment Of An Extensively Drug-Resistant Pseudomonal Ulcer Associated With Contaminated Artificial Tears, Sina Rezaei, Daniel W. Steen, Sejal R. Amin Dec 2023

Successful Treatment Of An Extensively Drug-Resistant Pseudomonal Ulcer Associated With Contaminated Artificial Tears, Sina Rezaei, Daniel W. Steen, Sejal R. Amin

Ophthalmology Articles

PURPOSE: To report a case of bacterial keratitis caused by an extensively drug-resistant (XDR) Pseudomonas aeruginosa strain linked to contaminated artificial tears in the United States. The ulcer was successfully treated without perforation or extracorneal spread.

OBSERVATIONS: An 81-year-old patient presented with a corneal ulcer of the right eye. The patient had a notable complex ocular history including glaucoma and corneal edema from corneal decompensation after prolonged retained lens fragment. Despite starting hourly fortified tobramycin and vancomycin eye drops, the infiltrate grew significantly by the next day. Bacterial culture grew Pseudomonas aeruginosa that was resistant to all tested antibiotics except …


A Critical Edition Of The Prefacing Dedicatory Letters In An Abridgement Of The Institution Of Christian Religion... (1586), Gwendolyn Fulkerson Dec 2023

A Critical Edition Of The Prefacing Dedicatory Letters In An Abridgement Of The Institution Of Christian Religion... (1586), Gwendolyn Fulkerson

University Honors Papers

HNRS 280 project

French text written by William Lawne

Text translated to English by Christopher Fetherstone

Critical edition and binding by Gwendolyn Fulkerson


Socioeconomic Geographies And Municipal Decision Making Of New York's Climate Smart Communities Program, Stephen Corbisiero Dec 2023

Socioeconomic Geographies And Municipal Decision Making Of New York's Climate Smart Communities Program, Stephen Corbisiero

Digital and Data Studies Student Scholarship

Nearly all of New York’s residents live in a municipality designated as a Climate Smart Community, but few are familiar with one of the state’s major legislative accomplishments. The initiative allows municipalities to earn points toward a climate smart certification by implementing sustainable technologies in their communities, which in turn makes them eligible for increased grant funding from New York State. As climate change begins to have a greater impact on human and natural life, investing in green infrastructure has never been more important. New York’s Climate Smart Communities program is widespread, but adoption rates vary greatly throughout the state …


Evaluation Of Current Monitoring Practices For Patients Receiving Infliximab, Yujin Hong Pharmd, Michael Schaedler Pharmd, Bcps, Bcop, Vincent Do Pharmd, Bcps, Bctxp Dec 2023

Evaluation Of Current Monitoring Practices For Patients Receiving Infliximab, Yujin Hong Pharmd, Michael Schaedler Pharmd, Bcps, Bcop, Vincent Do Pharmd, Bcps, Bctxp

Posters

  • Infliximab is used for a wide range of inflammatory conditions including Crohn’s disease, ulcerative colitis, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, and plaque psoriasis.
  • Patients should be closely monitored for development of signs and symptoms of active tuberculosis and latent infection, hepatitis B virus, and human immunodeficiency virus (HIV) during treatment with infliximab following termination of therapy.
  • Hematologic abnormalities have also been reported in patients receiving infliximab and caution should be exercised in patients being treated with infliximab who have ongoing or a history of significant hematologic abnormalities.
  • Patients with symptoms of signs of liver dysfunction should be evaluated for …


Evaluation Of Compliance To Brivaracetam Restrictions Within A Large Multicenter Health System, Meghan Mcnulty Pharmd, Mahmoud Amir Pharmd, Fccm, Bcps, Bcccp, Paul Ahearn, Michele Moura Pharmd, Bcps, Bcccp Dec 2023

Evaluation Of Compliance To Brivaracetam Restrictions Within A Large Multicenter Health System, Meghan Mcnulty Pharmd, Mahmoud Amir Pharmd, Fccm, Bcps, Bcccp, Paul Ahearn, Michele Moura Pharmd, Bcps, Bcccp

Posters

This evaluation aims to assess whether the health-system is adhering to brivaracetam prescribing restrictions and determine if there are any opportunities for improvement to the current ordering workflow.


A Brief History Of The Pas Interactive Drumming Committee, Robert J. Damm Dec 2023

A Brief History Of The Pas Interactive Drumming Committee, Robert J. Damm

CoE Publications

No abstract provided.


Landscape/Atmosphere Interactions And Carbon-Dioxide Dynamics In The Great Onyx Groundwater Basin, Mammoth Cave National Park, Kentucky, Meghan Raines Dec 2023

Landscape/Atmosphere Interactions And Carbon-Dioxide Dynamics In The Great Onyx Groundwater Basin, Mammoth Cave National Park, Kentucky, Meghan Raines

Masters Theses & Specialist Projects

An increase in atmospheric CO2 since the Industrial Revolution has altered rates of global climate change and has motivated a need to better quantify the flux of carbon between Earth’s reservoirs. Attempts to quantify the exchange of atmospheric carbon between sources and sinks have led to an increasing interest in the terrestrial landscape, including the continental carbon sink associated with carbonate-mineral dissolution. This research sought to better inform an understanding of karst landscapes and their relationship with global climate change through carbon cycling. The study utilized high-resolution data collection of pH, temperature, and specific conductance of waters in the Cascade …


Liquid Chromatography Mass Spectrometry Method Development For The Determination Of Β–Defensins In Bovine Milk, Elisha Ogbebor Dec 2023

Liquid Chromatography Mass Spectrometry Method Development For The Determination Of Β–Defensins In Bovine Milk, Elisha Ogbebor

Masters Theses & Specialist Projects

Bovine mastitis is caused by a wide range of pathogens which results in a substantial economic loss for the dairy cattle livestock industry. β-defensins are a part of the innate immune system and act as the first line of defense against mastitis in bovine. β-defensins (~6- 10kDa) are antimicrobial peptides that contain about 28 to 67 amino acids, the presence of six cysteine residues results in their three disulfide bonds and a β-sheet structure. A few β- defensins have been identified in cows based on the site of occurrence and time of expression in tissue, but not in milk. A …


Towards The Quantification Of Estrone And 17Β-Estradiol Conjugates In Dairy Cattle Urine Sorptive Stir Bar Extraction And Gas Chromatography-Mass Spectometry, S.M. Istiak Ahmed Dec 2023

Towards The Quantification Of Estrone And 17Β-Estradiol Conjugates In Dairy Cattle Urine Sorptive Stir Bar Extraction And Gas Chromatography-Mass Spectometry, S.M. Istiak Ahmed

Masters Theses & Specialist Projects

The global concern regarding the presence of compounds with estrogenic properties in the environment has grown significantly. Endocrine-disrupting compounds (EDCs) are environmental pollutants that disrupt the endocrine systems of both wildlife and humans. Estrogens, with their potent estrogenic effects, are particularly noteworthy among the various substances with endocrine-disrupting properties. They are of concern due to their prevalence in the environment, especially due to dairy waste contamination. These lipophilic compounds can accumulate in livestock fat tissues, potentially entering the human food chain. Sulfated forms of estrone and β- estriol, which exhibit a higher degree of saturation than their non-conjugated counterparts, have …


Bioactivity And Structural Properties Of Hydroxyapatite On Ti6a|4v And Si(100) Surfaces By Pulsed Laser Deposition, Salizhan Kylchbekov Dec 2023

Bioactivity And Structural Properties Of Hydroxyapatite On Ti6a|4v And Si(100) Surfaces By Pulsed Laser Deposition, Salizhan Kylchbekov

Masters Theses & Specialist Projects

Although biomedical implant technology is very advanced, there are still caveats in terms of biocompatibility properties because metals are inert to biological processes such as osseointegration, cell growth, and cell adhesion. This results in statistically significant complications and opens rooms for improvements. Among many techniques to improve this problem, coating the metal surface with biologically functional materials has resulted in the best performances. Hydroxyapatite (HAP), Ca₁₀(PO₄)₆(OH)₂, is the most stable form of calcium phosphates in human body environment and is functional in key processes such as ion exchange, osteoblast (bone cells) formation, …


The Socialization Of Social Media: Examining The Impact Of Social Media Use On Interpersonal Skills During Face-To-Face Interaction, Tenille Thomas Dec 2023

The Socialization Of Social Media: Examining The Impact Of Social Media Use On Interpersonal Skills During Face-To-Face Interaction, Tenille Thomas

Masters Theses & Specialist Projects

Research has well established that the use of social networking sites (SNS) has increased accessibility and connectivity to people with limitless boundaries. SNS have progressively become the preferred source of communication. However, often overlooked is the impact SNS use has on face-to-face interactions, specifically on interpersonal skills. The purpose of this study was to examine the relationship between SNS use and face-to-face interaction. Specifically, this study examines the participant’s ability to recognize and interpret nonverbal cues with increased SNS use. This was a correlational study utilizing a quantitative design of self-reported questionnaires. A total of 178 participants, ranging in age …


Adaptable Object And Animation System For Game Development, Isaiah Turner Dec 2023

Adaptable Object And Animation System For Game Development, Isaiah Turner

Masters Theses & Specialist Projects

In contemporary times, video games have swiftly evolved into a prominent medium, excelling in both entertainment and narrative delivery, positioning themselves as significant rivals to traditional forms such as film and theater. The burgeoning popularity of gaming has led to a surge in aspiring game developers seeking to craft their own creations, driven by both commercial aspirations and personal passion. However, a common challenge faced by these individuals involves the considerable time investment required to acquire essential skills and establish a foundational framework for their projects. Accessible game development engines that offer a diverse range of fundamental features play a …


Combining Adhesive And Nonadhesive Injectable Hydrogels For Intervertebral Disc Repair In An Ovine Discectomy Model., Christopher J Panebianco, Caroline Constant, Andrea J. Vernengo, Dirk Nehrbass, Dominic Gehweiler, Tyler J Distefano, Jesse Martin, David J Alpert, Saad B Chaudhary, Andrew C Hecht, Alan C Seifert, Steven B Nicoll, Sibylle Grad, Stephan Zeiter, James C Iatridis Dec 2023

Combining Adhesive And Nonadhesive Injectable Hydrogels For Intervertebral Disc Repair In An Ovine Discectomy Model., Christopher J Panebianco, Caroline Constant, Andrea J. Vernengo, Dirk Nehrbass, Dominic Gehweiler, Tyler J Distefano, Jesse Martin, David J Alpert, Saad B Chaudhary, Andrew C Hecht, Alan C Seifert, Steven B Nicoll, Sibylle Grad, Stephan Zeiter, James C Iatridis

Henry M. Rowan College of Engineering Departmental Research

BACKGROUND: Intervertebral disc (IVD) disorders (e.g., herniation) directly contribute to back pain, which is a leading cause of global disability. Next-generation treatments for IVD herniation need advanced preclinical testing to evaluate their ability to repair large defects, prevent reherniation, and limit progressive degeneration. This study tested whether experimental, injectable, and nonbioactive biomaterials could slow IVD degeneration in an ovine discectomy model.

METHODS: Ten skeletally mature sheep (4-5.5 years) experienced partial discectomy injury with cruciate-style annulus fibrosus (AF) defects and 0.1 g nucleus pulposus (NP) removal in the L1-L2, L2-L3, and L3-L4 lumbar IVDs. L4-L5 IVDs were Intact controls. IVD injury …