Digital Commons Network^™

The Influence Of Aviation Technology On Human Complacency, Aurora Burton

Honors Theses

The thesis covers automation complacency in the aviation industry. The purpose being to provide a foundation of complacency-related accidents to support or dismiss the Federal Aviation Administration’s claim to automation-induced inattention. Complacency factors are outlined in a multitude of fields, creating a background for aviation discussion. To outline the parameters of literature review, behaviors associated with complacency are addressed. Next, a compilation of accident reports is examined and categorized. Specific, impactful accidents relating to complacency are detailed and explained. Summarily, three solutions to human-driven complacency are proposed, evaluated, and analyzed. Including the following: proficiency advancement, technology improvement, and change in …

Identifying The Drivers Of Pollen Limitation In Apples (Malus Domestica) Within The Urban Orchards Of St. Louis, Mo, Jordan Hathaway

Theses

The human population is projected to continue growing throughout the remainder of the 21st century. Thus, agricultural production will need to increase drastically in order to ensure global food security. Management strategies aimed at enhancing crop pollination by promoting pollinator diversity have shown potential as an environmentally sustainable method of increasing yields. Optimizing the design and implementation of these strategies will require us to expand our understanding of the processes which influence crop pollen limitation. In this study, we examined pollen limitation in self-incompatible apple trees (Malus domestica) within urban orchards located in St. Louis, MO. In our first field …

Beyond Words: An Exploration Of Research And Writing For Indigenous Land Acknowledgements, Oksana Flores

Master of Arts in Professional Writing Capstones

This capstone delves into the practical application and importance of land acknowledgments within the frameworks of Critical Indigenous Theory and Narrative Theory. Through the utilization of archival research methods, the project not only offers recommendations for crafting an effective land acknowledgment but also provides the necessary historical foundation for the implementation of such a statement at Kennesaw State University. This effort serves to strengthen the university's commitment to diversity and equity on campus.

Thunderfort, Lever Stewart

Master of Arts in Professional Writing Capstones

Thunderfort is a tabletop roleplaying game (TTRPG) that utilizes both synchronous and asynchronous communication in both its rules and its fictitious setting. This project seeks to provide a unique TTRPG experience that is partially or fully digital, played out via text chatting and digital dice rolling. Such a game is also intended to be enjoyed by players without said players needing to worry about game session scheduling conflicts, since a large part of the game is played via digital, asynchronous communication. The full, most up-to-date text can also be accessed at thunderfort.lsflegal.com.

Phi-1, An Endogenous Inhibitor Protein For Protein Phosphatase-1 And A Pan-Cancer Marker, Regulates Raf-1 Proteostasis, Jason Kirkbride, Garbo Nilsson, Jee In Kim, Kosuke Takeya, Yoshinori Tanaka, Hiroshi Tokumitsu, Futoshi Suizu, Masumi Eto

Kimmel Cancer Center Faculty Papers

Raf-1, a multifunctional kinase, regulates various cellular processes, including cell proliferation, apoptosis, and migration, by phosphorylating MAPK/ERK kinase and interacting with specific kinases. Cellular Raf-1 activity is intricately regulated through pathways involving the binding of regulatory proteins, direct phosphorylation, and the ubiquitin-proteasome axis. In this study, we demonstrate that PHI-1, an endogenous inhibitor of protein phosphatase-1 (PP1), plays a pivotal role in modulating Raf-1 proteostasis within cells. Knocking down endogenous PHI-1 in HEK293 cells using siRNA resulted in increased cell proliferation and reduced apoptosis. This heightened cell proliferation was accompanied by a 15-fold increase in ERK1/2 phosphorylation. Importantly, the observed …

Considering The Price-Anderson Act's Federal Public Liability Action Provisions In The Future Of Nuclear Fusion Power, Pearle M. Lipinski

Colorado Technology Law Journal

No abstract provided.

Never-Ending Parenting: Challenges Experienced By Caregivers Of Adults With Severe Autism, Andrea Palerino

Dissertations

Despite the large number of children with autism spectrum disorder (ASD) who are annually aging out of the school-based systems in the United States, much of the academic literature has been focused on the concerns and challenges of preschool or school-aged children with ASD. As a result, there lacks a clear understanding of how primary caregivers of adult children with severe autism spectrum disorder (SASD) utilize various forms of capital to navigate care.

This study proposed to fill that gap by employing Bourdieu's notions of capital as a theoretical framework for the interview protocol to address accessing community services, securing …

Gina Park Senior Piano Recital, Andrews University

Student Degree Recitals 2023-2024

Gina Park presents a senior recital titled "Journey".

Featuring works of Schumann, Schubert and Kapustin.

Seresa, Jerwin Bilale

Katipunan

Umiinog ang sanaysay na Seresa mula sa personal na karanasan tungo sa kolektibo’t sala-salabat na danas ng pagiging isang kontraktuwal na manggagawa sa industriya ng Call Center sa Pilipinas. Layong pagnilayan sa akda ang nakapanlulumong realidad ng kawalang katiyakan at mga kagyat na pamamaalam (hal., mababang sahod, kawalan ng regularisasyon, kakulangan ng oportunidad, atrasadong kompetisyon, atbp.) na siyang nag-uugnay o hindi kaya’y nagiging dahilan pa ng pagkakawatak-watak ng mga mamamayang biktima lamang ng isang sistemang kontra-manggagawa. Sa ganitong paraan, naitutuon ang naratibo hindi na lamang sa sariling sitwasyon kundi sa mas malawak, masalimuot na konteksto ng prekaridad na kinahaharap ng …

Talim, Taks Barbin

Katipunan

Sa kuwentong itong nasa sipat ng isang beterinaryo, isinasalaysay ang pagbabago ng tauhang si Into mula sa pagiging mapayapang indibidwal tungo sa isang taong handang pumatay. Nakalunan sa isla ng Talim sa Rizal ang nasabing kuwento, at iinog sa asong si Puti na tanging kasama ni Into. Sa kuwento, ipinababatid din ang mga pagbabagong hatid ng industriyalisasyon at pangangamkam ng lupa, hindi lang sa tauhan, kundi pati sa kalikasang ginagalawan. Ito ang naging mitsa sa pagsasakatuparan ng paghahanap ng hustisyang hindi maibigay ng mga awtoridad sa kuwento.

Kung Sa Bawat Pagtawag Ay Pagtawid Sa Gubat, Alec Joshua Paradeza

Katipunan

Tatlong araw nang binabagtas ni Ruel ang kabundukan sa ilalim ng malakas na ulan. Tumatakas siya mula sa militar, kasama ng iba pang gerilya. Dala ng pagod at gutom, hiniling ni Ruel na bumalik sa mga mundong binisita noon—mga mundong labas sa sarili niyang mundo, kasama ang dating karelasyon na si Ino. Sa pagkalunod sa alaala ay hindi niya namalayan ang nakausling ugat sa dinaraanan at napatid, lumubog ang mukha sa putik. Sa gitna ng bagyo ay babalikan niya ang unang beses na hinatak siya ni Ino mula sa bundok tungo sa isang hotel. Ipinaliwanag sa kaniya ng karelasyon na …

Hnf4Α Isoforms Regulate The Circadian Balance Between Carbohydrate And Lipid Metabolism In The Liver, Jonathan R Deans, Poonamjot Deol, Nina Titova, Sarah H Radi, Linh M Vuong, Jane R Evans, Songqin Pan, Johannes Fahrmann, Jun Yang, Bruce D Hammock, Oliver Fiehn, Baharan Fekry, Kristin Eckel-Mahan, Frances M Sladek

Faculty, Staff and Student Publications

Hepatocyte Nuclear Factor 4α (HNF4α), a master regulator of hepatocyte differentiation, is regulated by two promoters (P1 and P2) which drive the expression of different isoforms. P1-HNF4α is the major isoform in the adult liver while P2-HNF4α is thought to be expressed only in fetal liver and liver cancer. Here, we show that P2-HNF4α is indeed expressed in the normal adult liver at Zeitgeber time (ZT)9 and ZT21. Using exon swap mice that express only P2-HNF4α we show that this isoform orchestrates a distinct transcriptome and metabolome via unique chromatin and protein-protein interactions, including with different clock proteins at different …

Digital Pulse: Unraveling The Complexities Of Ai-Enabled Hypertension Management In African American Communities, Keisha Lovence

Sigma Foundation for Nursing Research Grant Reports

The main objective of this grant is to study the factors that impact the use of AI-powered tools for managing hypertension among African Americans with high blood pressure. Specifically, we aim to understand how cognitive and emotional factors such as health beliefs, digital literacy, and treatment adherence interact with aspects like stigmatization, community involvement, and cultural identity. By examining these elements, we hope to gain insights into the acceptance and utilization of AI technology in hypertension self-management within the American community. This knowledge can help us design and implement interventions tailored to their needs. Our investigation will explore the aspects …

Plasma Exchange Reduces Aβ Levels In Plasma And Decreases Amyloid Plaques In The Brain In A Mouse Model Of Alzheimer's Disease, Santiago Ramirez, Suelyn Koerich, Natalia Astudillo, Nicole De Gregorio, Rabab Al-Lahham, Tyler Allison, Natalia Pessoa Rocha, Fei Wang, Claudio Soto

Faculty, Staff and Student Publications

Alzheimer's disease (AD) is the most common type of dementia, characterized by the abnormal accumulation of protein aggregates in the brain, known as neurofibrillary tangles and amyloid-β (Aβ) plaques. It is believed that an imbalance between cerebral and peripheral pools of Aβ may play a relevant role in the deposition of Aβ aggregates. Therefore, in this study, we aimed to evaluate the effect of the removal of Aβ from blood plasma on the accumulation of amyloid plaques in the brain. We performed monthly plasma exchange with a 5% mouse albumin solution in the APP/PS1 mouse model from 3 to 7 …

Testing The Boundaries Of Torture: Forced Circumcision As A Crime Against Humanity, Marina Coriale

Cardozo International & Comparative Law Review (CICLR) Blog

Female genital mutilation (FGM) has history that extends across countless cultures and regions, impacting women and girls around the world still searching for redress and reparations. Knowing this, the international community should understand the necessity of providing a space for FGM survivors in the International Criminal Court (ICC).

This post was originally published on the Cardozo International & Comparative Law Review on December 4, 2023. The original post can be accessed via the Archived Link button above.

Examining The Potential Of Vitamin C Supplementation In Tissue-Engineered Equine Superficial Digital Flexor Tendon Constructs, Michael J Mienaltowski, Mitchell Callahan, Nicole L Gonzales, Angelique Wong

Faculty, Staff and Student Publications

Because equine tendinopathies are slow to heal and often recur, therapeutic strategies are being considered that aid tendon repair. Given the success of utilizing vitamin C to promote tenogenesis in other species, we hypothesized that vitamin C supplementation would produce dose-dependent improvements in the tenogenic properties of tendon proper (TP) and peritenon (PERI) cells of the equine superficial digital flexor tendon (SDFT). Equine TP- and PERI-progenitor-cell-seeded fibrin three-dimensional constructs were supplemented with four concentrations of vitamin C. The gene expression profiles of the constructs were assessed with 3'-Tag-Seq and real-time quantitative polymerase chain reaction (RT-qPCR); collagen content and fibril ultrastructure …

The Role Of Shared Leadership In Realizing Sdgs: An Exploration Of Intra-Country Collaborative Work Between Heis And Public Policy Groups In Zambia, Chitalu Kabwe, Christine Phiri-Mushibwe, Smita Tripathi

Plymouth Business School

This chapter employs the shared leadership model in exploring how leaders of higher education institutions (HEIs) can partner with Public Policy Groups (PPGs) within the Global South, a region characterized by complex challenges such as underdeveloped economies, corrupt leadership, limited financial and human resources, and political instability in some cases. The driving forces for collaboration include interconnected national policies, shared goals, responsibility, and accountability for resources. The Zambian Higher Education Policy (HE policy) draws on national, regional, and global aspirations for education and skills development, making it a suitable tool for advancing a common agenda for social, economic, and environmental …

Transient Receptor Potential Vanilloid 4-Dependent Microglial Function In Myelin Injury And Repair, Jameson P Holloman, Sophia H Dimas, Angela S Archambault, Fabia Filipello, Lixia Du, Jing Feng, Yonghui Zhao, Bryan Bollman, Laura Piccio, Andrew J Steelman, Hongzhen Hu, Gregory F Wu

2020-Current year OA Pubs

Microglia are found pathologically at all stages of multiple sclerosis (MS) lesion development and are hypothesized to contribute to both inflammatory injury and neuroprotection in the MS brain. Transient receptor potential vanilloid 4 (TRPV4) channels are widely expressed, play an important role as environmental sensors, and are involved in calcium homeostasis for a variety of cells. TRPV4 modulates myeloid cell phagocytosis in the periphery and microglial motility in the central nervous system. We hypothesized that TRPV4 deletion would alter microglia phagocytosis in vitro and lessen disease activity and demyelination in experimental autoimmune encephalitis (EAE) and cuprizone-induced demyelination. We found that …

Racial Difference In Mortality Among Covid-19 Hospitalizations In California, Muni Rubens, Venkataraghavan Ramamoorthy, Anshul Saxena, Juan Zevallos, Md Ashfaq Ahmed, Zhenwei Zhang, Peter Mcgranaghan, Sandra Chaparro, Javier Jimenez

All Publications

In the US, racial disparities in hospital outcomes are well documented. We explored whether race was associated with all-cause in-hospital mortality and intensive care unit (ICU) admission among COVID-19 patients in California. This was a retrospective analysis of California State Inpatient Database during 2020. Hospitalizations ≥ 18 years of age for COVID-19 were included. Cox proportional hazards with mixed effects were used for associations between race and in-hospital mortality. Logistic regression was used for the association between race and ICU admission. Among 87,934 COVID-19 hospitalizations, majority were Hispanics (56.5%), followed by White (27.3%), Asian, Pacific Islander, Native American (9.9%), and …

Prevalence, Characteristics, And Correlates Of Probable Avoidant/Restrictive Food Intake Disorder Among Adult Respondents To The National Eating Disorders Association Online Screen: A Cross-Sectional Study, Laura D'Adamo, Lauren Smolar, Katherine N Balantekin, C Barr Taylor, Denise E Wilfley, Ellen E Fitzsimmons-Craft

2020-Current year OA Pubs

BACKGROUND: Avoidant/restrictive food intake disorder (ARFID) is a serious, albeit under-researched, feeding or eating disorder. This exploratory study utilized data from adult respondents to the National Eating Disorders Association online eating disorder screen to validate items assessing the presence of ARFID and examine the prevalence, clinical characteristics, and correlates of a positive ARFID screen.

METHODS: Among 50,082 adult screen respondents between January 2022 and January 2023, the prevalence of a positive ARFID screen was calculated. Chi-square tests and t-tests compared demographics, eating disorder attitudes and behaviors, suicidal ideation, current eating disorder treatment status, and eating disorder treatment-seeking intentions between respondents …

Agreement Between Published Reference Resources For Neurofilament Light Chain Levels In People With Multiple Sclerosis., Elias S Sotirchos, Chen Hu, Matthew D Smith, Hannah-Noelle Lord, Anna L Duval, Georgina Arrambide, Xavier Montalban, Katja Akgün, Tjalf Ziemssen, Robert T Naismith, Carrie M Hersh, Megan Hyland, Lauren B Krupp, Jacqueline A Nicholas, Robert A Bermel, Ellen M Mowry, Peter A Calabresi, Kathryn C Fitzgerald

Neuroscience Articles

OBJECTIVES: To examine the agreement between published reference resources for neurofilament light chain (NfL) applied to a large population of people with multiple sclerosis (MS).

METHODS: Six published reference resources were used to classify NfL in participants in the Multiple Sclerosis Partners Advancing Technology and Health Solutions (MS PATHS) network as elevated or normal and to derive age-specific NfL

RESULTS: NfL measurements were assessed from 12,855 visits of 6,687 people with MS (median 2 samples per individual [range 1-7]). The mean ± SD age was 47.1 ± 11.7 years, 72.1% of participants were female, disease duration was 15.0 ± 10.6 …

Prevalence, Faunal Composition, And Vertical Distribution Of Bioluminescence In The Pelagic Gulf Of Mexico: Fishes, Crustaceans, Cephalopods And Gelatinous Megaplankton, Devynne M. Brown

All HCAS Student Capstones, Theses, and Dissertations

Bioluminescence is the phenomenon of light emission by living organisms. It occurs through a chemical reaction within an organism and serves various purposes. The diversity of bioluminescent capabilities and occurrence in unrelated taxa suggest that bioluminescence has evolved independently numerous times amongst taxa thriving in certain environments. One such environment is the deep ocean, where little to no sunlight penetrates the water column, specifically in the mesopelagic (200-1000 m depth) and bathypelagic (> 1000 m) zones. The mesopelagic and bathypelagic zones have been extensively sampled and well documented in the Gulf of Mexico (GoM), one of the few places globally …

Evaluating The Effectiveness Of The Internal Transcribed Sequences (Its) As Dna Barcodes To Estimate Fungal Diversity, Jailisa Linares

All HCAS Student Capstones, Theses, and Dissertations

Universal phylogenetic markers such as the nuclear ribosomal internal transcribed sequences (ITS), specifically ITS1 and ITS2, are routinely used to estimate fungal diversity in environmental samples. However, numerous studies report differences in the performance and efficacy of ITS1 and ITS2 in documenting fungal diversity. To better understand the implications of using ITS1 versus ITS2, a comprehensive representation of the diverse fungal taxa was necessary to conduct a meta-analysis of their use across multiple fungal taxa. In order to address this, a thorough literature review was conducted to compare and contrast the use of ITS1 and ITS2 as effective DNA barcodes. …

Suction Circuit Flushing With Chlorhexidine Decreases Ventilator-Associated Pneumonia: A Quasi-Experimental Study, Mohamed H. Eid, Monica –.Marilena Ţânţu, Jos M. Latour, Mohammed Ahmed Sultan, Nahed Attia Kandeel

School of Nursing and Midwifery

Background: Endotracheal suctioning of mechanically ventilated patients differs across the world. In many low and middle-income countries, endotracheal suctioning is often performed with a sterile suctioning catheter that is used for 12 h or during the length of one nursing shift. The effect of flushing multiple used endotracheal suction system with chlorhexidine after suctioning to reduce ventilator associated pneumonia (VAP) remains unclear. Aim: The aim of the study is to assess the effectiveness of flushing multiple-used open endotracheal suction catheters and suctioning system with chlorhexidine gluconate 0.2% to reduce VAP in mechanically ventilated patients in a resource-limited Intensive Care Unit …

A Quest For An Integrated Management System Of Children Following A Drowning Incident: A Review Of The Literature., S Rossaouw, Carin Maree, Jos M. Latour

School of Nursing and Midwifery

Purpose Management of children following a drowning incident is based on specific interventions which are used in the prehospital environment, the emergency department (ED) and the Paediatric Intensive Care Unit (PICU). This paper presents a review of the literature to map and describe the management and interventions used by healthcare professionals when managing a child following a drowning incident. Of specific interest was to map, synthesise and describe the management and interventions according to the different clinical domains or practice areas of healthcare professionals. Design and Methods A traditional review of the literature was performed to appraise, map and describe …

Aghedo V. 80 Clarkson Llc

All Decisions

In this HP proceeding, tenants sought to correct housing maintenance code violations and obtain civil penalties against the landlords. The court granted the tenants' motion for an order to correct the violations, directing the landlords to rectify them by a specified date. However, the motion for civil penalties was denied without prejudice to renew, as triable issues of fact existed regarding the landlords' liability. The court emphasized the need to resolve issues related to access and cited a consent order in a related action, extending the deadline for corrections.

Maternal Diet During Early Gestation Influences Postnatal Taste Activity-Dependent Pruning By Microglia, Chengsan Sun, Shuqiu Zheng, Justin S A Perry, Geoffrey T Norris, Mei Cheng, Fanzhen Kong, Rolf Skyberg, Jianhua Cang, Alev Erisir, Jonathan Kipnis, David L Hill

2020-Current year OA Pubs

A key process in central sensory circuit development involves activity-dependent pruning of exuberant terminals. Here, we studied gustatory terminal field maturation in the postnatal mouse nucleus of the solitary tract (NST) during normal development and in mice where their mothers were fed a low NaCl diet for a limited period soon after conception. Pruning of terminal fields of gustatory nerves in controls involved the complement system and is likely driven by NaCl-elicited taste activity. In contrast, offspring of mothers with an early dietary manipulation failed to prune gustatory terminal fields even though peripheral taste activity developed normally. The ability to …

Intraoperative Neuromonitoring, Xian Boles

Theses

The purpose of this project is to increase accessibility to safe surgical practices by educating medical professionals on the complex topic of intraoperative neuromonitoring (IONM). Working in collaboration with content advisor and neurosurgeon Dr. Wenya Linda Bi and her neuromonitoring team, Mitali Bose, CNIM, and Matthew Toczylowski, CNIM, an online, interactive training module has been developed and hosted on the Brigham and Women’s Hospital Skull Base Laboratory website. The training module covers various monitoring modalities, safety techniques, electrode setups, and clinical applications through a series of 2D illustrations and 3D interactive Sketchfab models. A total of five interactive models and …

Changing The Playbook For Immigrant Health, Cheryl Bettigole, Patricia C. Henwood, Sage Myers, Maura Sammon

Department of Emergency Medicine Faculty Papers

Philadelphia’s response to welcoming Afghan evacuees during the COVID-19 pandemic suggests the need for a new approach to immigrant health care.

Chimes: December 4, 2023, Calvin University

Chimes

Calvin building projects abound: where's the money coming from? by Savannah Shustack & Grace Buller

Campus leadership works to implement safety measures by Ashley Hamons

Fall sports wrap up as winter sports hit the ground running by Dillion Baumchen

KIM gives students real-world experience in investment management by Ethan Meyers

Calvin enters partnership to encourage civic engagement among students by Savannah Shustack

Calvin Alumni gives an on-campus talk about his experience at an aerospace startup by Jacob Westra

When cherished beliefs are challenged: Calvin students wrestle with hard questions by Nolan Cowan & Ethan Meyers

Q&A with Calvin's Career Center …