Digital Commons Network^™

Caretaker Burnout In Nj In Response To The Covid-19 Pandemic: A Study Focusing On Quality Of Life, Challenges And Coping Strategies., Abdullah Junayed, Joanna Petrides

Rowan-Virtua Research Day

There is a scarcity of literature regarding caretaker burnout in response to Covid-19, however one cross section survey study in Italy explored the perceived burden of caretakers of patients with Alzheimer’s disease during the pandemic.1 Maria G. Maggio et al showed that an increase in caregiver burden allowed for a deterioration in personal health conditions causing an increase in perceived stress levels. 1 Along with impaired management of stress and low quality of life, many caretakers were found to utilize avoidance strategies.1 However, the authors pointed out that the dysfunctional coping strategies did not affect stress levels and this study …

Extravasated Brain-Reactive Autoantibodies Perturb Neuronal Surface Protein Expression In Alzheimer's Pathology, Wardah Bajwa, Mary Kosciuk, Randel L. Swanson, Anuradha Krishnan, Venkat Venkataraman, Robert Nagele, Nimish Acharya

Rowan-Virtua Research Day

Background: Increased blood-brain barrier (BBB) permeability is reported in both the neuropathological and in vivo studies in both Alzheimer’s Disease (AD) and age matched cognitively normal, no cognitive impairment (NCI), subjects. Impaired BBB allows various vascular components such as immunoglobulin G (IgG) to extravasate into the brain and specifically bind to various neuronal surface proteins (NSP), also known as brain reactive autoantibodies (BrABs). This interaction is predicted to further enhance deposition of amyloid plaques.

Hypothesis: Interaction between extravasated BrABs and its cognate NSPs lower the expression of that NSPs in AD patients.

Methods: We selected Western blotting technique to study …

Leadership Education In A Changing World: The Efficacy Of Service-Learning As A Pedagogical Asset In Online University Leadership Courses, Sam Perry

Student Scholarship

The purpose of this study is to explore the domains of service-learning, leadership education, and online education to generate new ideas relevant to providing a comprehensive educational experience that successfully aids students to lead in subsequent positions. This is an in integrative literature review with supporting information from 35 sources including journals, books, dissertations, relevant media, and surveys that are used to discuss leadership education, online education, service-learning, and the leadership development potential for students when service-learning assignments are utilized in online leadership courses. Themes from each section will be identified and combined to produce new ideas in employing service-learning …

We Are ... Marshall, May 3, 2023, Office Of Marshall University Communications

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

The Association Of Dementia Caregiver Employment With Sleep Quality: Does Being A Spouse Matter?, Jasnoor Kaur

Honors College Theses

Background: Family caregivers for a person living with dementia (PLwD) can experience stress and burden which may relate to health consequences such as poor sleep quality. This study aimed to 1) examine the association between caregiver employment status and sleep quality and 2) understand how this association may be moderated by the relationship of the caregiver to the PLwD.

Methods: A sample of primary caregivers for a PLwD (N = 100) were interviewed in person in 2017. A linear regression with the Pittsburgh Sleep Quality Index (PSQI) global score as the outcome and employment status as the key predictor, and …

Tele-Sim For Nurse Practitioner Clinical Education: An Online, Real-Time, Educational Innovation Using Simulation And Telehealth For Learning Physical Assessment Skills, Kat Tremblay

Doctor of Nursing Practice (DNP) Translational and Clinical Research Projects

Background: Increasing numbers of nurse practitioner (NP) educational programs are being offered online, with little or no face-to-face contact among students and instructors. Students express lack of confidence in their physical examination skills and want live instructor demonstrations, observed practice, and real-time feedback from their clinical instructors.

Significance: NP students need to acquire physical examination skills to increase competency in assessing patients for enhanced clinical judgment and improved patient outcomes.

Purpose/Aims: to improve and measure the competency and confidence in the performance of advanced physical assessment skills of NP students in an advanced health assessment (AHA) clinical course with an …

Effect Of High Fat Vs High Sugar Diet On Mtor Signaling Pathway In Skeletal Muscle Of Male And Female Mice, Zereque Powell

Electronic Theses and Dissertations Archive

Background: Obesity and MetS has been shown to negatively impact protein synthesis rates. Objective: Determine the effects of sex and high fat/high sugar diets on mTOR signaling pathways. Methods: 15 male and 15 female wild type C57BL/6 mice were randomized into 3 groups: High Fat (45% fat), High Sugar (60% carb) and Control. While continuing diets, body weight and body composition were monitored. Following sacrifice, muscles were examined for changes in the mTOR signaling pathway. Results: Mice consuming the HF diet had the highest levels of weight gain. Females expressed higher levels of expression of P-AMPK. Levels of REDD1 were …

Association Of Mitochondrial Dna Copy Number With Brain Mri Markers And Cognitive Function: A Meta-Analysis Of Community-Based Cohorts, Yuankai Zhang, Xue Liu, Kerri L Wiggins, Nuzulul Kurniansyah, Xiuqing Guo, Amanda L Rodrigue, Wei Zhao, Lisa R Yanek, Scott M Ratliff, Achilleas Pitsillides, Juan Sebastian Aguirre Patiño, Tamar Sofer, Dan E Arking, Thomas R Austin, Alexa S Beiser, John Blangero, Eric Boerwinkle, Jan Bressler, Joanne E Curran, Lifang Hou, Timothy M Hughes, Sharon L R Kardia, Lenore J Launer, Daniel Levy, Thomas H Mosley, Ilya M Nasrallah, Stephen S Rich, Jerome I Rotter, Sudha Seshadri, Wassim Tarraf, Kevin A González, Vasan Ramachandran, Kristine Yaffe, Paul A Nyquist, Bruce M Psaty, Charles S Decarli, Jennifer A Smith, David C Glahn, Hector M González, Joshua C Bis, Myriam Fornage, Susan R Heckbert, Annette L Fitzpatrick, Chunyu Liu, Claudia L Satizabal

Faculty, Staff and Student Publications

BACKGROUND AND OBJECTIVES: Previous studies suggest that lower mitochondrial DNA (mtDNA) copy number (CN) is associated with neurodegenerative diseases. However, whether mtDNA CN in whole blood is related to endophenotypes of Alzheimer disease (AD) and AD-related dementia (AD/ADRD) needs further investigation. We assessed the association of mtDNA CN with cognitive function and MRI measures in community-based samples of middle-aged to older adults.

METHODS: We included dementia-free participants from 9 diverse community-based cohorts with whole-genome sequencing in the Trans-Omics for Precision Medicine (TOPMed) program. Circulating mtDNA CN was estimated as twice the ratio of the average coverage of mtDNA to nuclear …

An Investigation Of Resistance Training Behavior, Non-Specific Psychological Distress, And Perceived Barriers To Resistance Training In Self-Identifying Female Undergraduate Students, Jody Sobel

Master's Theses

The prevalence and severity of depression symptoms amongst college students, specifically female identifying undergraduate students, is worrisome. There is a great deal of research that suggests a relationship between exercise, specifically resistance training (RT), and mental health. That said, current literature suggests that many female identifying students are not engaging due to perceived barriers. This, perhaps because of the plethora of barriers one can perceive. The purpose of this study was multifold 1) to examine the prevalence and severity of non-specific psychological distress; 2) to determine if there were differences between Kessler 6 Non-Specific Psychological Distress Scale (K6) categories (i.e., …

Lgbtq+ In A Rural Kentucky Town, Caroline A. Kinsman

Honors Theses

This interview series aims to understand the perspectives of LGBTQ+ community members in relation to local government in a small rural town in Kentucky. The purpose is to ascertain the correlation between the LGBTQ+ community's level of feeling accepted and the efforts and attitudes of non-LGBTQ+ officials. In total, six LGBTQ+ individuals were interviewed, and two elected government officials. Themes found within the interview series include reputation, safety, mental health, urgent change, blindness, and lack of responsibility.

Murphy, Jr., George, Dpaac Staff

Manuscript Division Finding Aids

Collection Number: Inclusive Dates: 1883 - 1985 Extent: 86 Cubic Feet Description: George B. Murphy, Jr. was born into the prominent and prosperous family that built the Afro-American newspaper and went on to fight for anti-racist and anti-colonialist causes throughout his life. His collection contains subject files and correspondence regarding people and organizations he was involved with.

Nicotinamide Riboside And Beta-Hydroxybutyrate Activate Parallel Pathways For C. Elegans Lifespan Extension, Mckenzie Peters

Undergraduate Honors Theses

Supplementation with nicotinamide riboside (NR), a form of vitamin B3 and a precursor of nicotinamide adenine dinucleotide (NAD⁺) extends lifespan in the nematode C. elegans and delays aging-related pathologies in mammals. During aging, levels of NAD⁺ decline causing metabolic dysfunction and oxidative damage. Studies in C. elegans found that when NR was administered during larval development it induced the mitochondrial unfolded protein response (UPR^mt), which is frequently associated with lifespan extension. Both calorie restriction (CR) and ketogenic diets (KD) have been shown to extend lifespan, in part through increasing NAD⁺ and through increasing levels …

Enhancing Health Tweet Classification: An Evaluation Of Transformer-Based Models For Comprehensive Analysis, Foram Pankajbhai Patel

Computer Science and Engineering Theses - Archive

The task of health tweet classification entails identifying whether a given tweet is health-related or not. While existing research in this area has made significant progress in classifying tweets into specific sub-domains of health, such as mental health, COVID-19, or specific diseases, there is a need for a more comprehensive approach that considers a broader range of health-related topics. This thesis addresses this need by proposing a diverse and comprehensive dataset that includes various existing health-related datasets, data collected through a keyword-based approach, and manually annotated data. However, the use of health-related keywords in a figurative or non-health context poses …

Graduate List - May 2023, University Of Nebraska At Omaha

Commencement Lists

No abstract provided.

Medication Safety In Community-Dwelling Older Adults, Fatoumata Jallow

Nursing Dissertations - Archive

This article-based thesis comprises two manuscripts on medication safety strategies in community-dwelling older adults. A phenomenological method was used to conduct semi-structured interviews with 28 community-dwelling older adults over 65 years who took five or more prescription medications daily. Caregivers were encouraged to participate in interviews. The objective of the first manuscript was to explore the roles of patients, pharmacists, and providers in medication safety from the perspective of community-dwelling older adults. Inductive thematic analysis revealed six themes indicating varying perceived roles of medication safety by older adults. In addition, results show that the provider and pharmacist roles overlap but …

Early Therapeutic Effects Of An Angiopoietin-1 Mimetic Peptide In Middle-Aged Rats With Vascular Dementia, Hua Gao, Elizabeth L. Findeis, Lauren Culmone, Brianna Powell, Julie Landschoot-Ward, Alex Zacharek, Trueman Wu, Mei Lu, Michael Chopp, Poornima Venkat

Neurology Articles

BACKGROUND: Vascular Dementia (VaD) refers to dementia caused by cerebrovascular disease and/or reduced blood flow to the brain and is the second most common form of dementia after Alzheimer's disease. We previously found that in middle-aged rats subjected to a multiple microinfarction (MMI) model of VaD, treatment with AV-001, a Tie2 receptor agonist, significantly improves short-term memory, long-term memory, as well as improves preference for social novelty compared to control MMI rats. In this study, we tested the early therapeutic effects of AV-001 on inflammation and glymphatic function in rats subjected to VaD.

METHODS: Male, middle-aged Wistar rats (10-12 m), …

Impacts Of Personal Cultural Orientations On College Students’ Psychological Health And Preventive Behaviors During The Covid-19 Period, Joanna Ouyang

Honors Theses

The COVID-19 pandemic has brought dramatic life changes to individuals across the world. Personal cultural orientations of these individuals alter the way individuals respond to the pandemic and their mental wellness. This research investigates how personal cultural orientations impact college students’ mental health primarily anxiety, prevention behaviors and intentions to reduce the spread of COVID-19, and active coping strategies during the COVID-19 pandemic. Participants (n=155) completed measures of independence, ambiguity intolerance, masculinity, gender equality, mental health, prevention behaviors to reduce the spread of COVID-19, and active coping strategies to protect themselves during the pandemic. Results revealed that people with higher …

Mathematics Library News, Aaron Lercher

Faculty Publications

Mathematics Library News is an LSU Libraries newsletter for members of the Mathematics and Experimental Statistics Departments, published roughly once each semester.

Aging In Westborough: A Community Needs Assessment, Ceara Somerville, Caitlin Coyle, Mary Krebs, Holly Stockdale

Center for Social and Demographic Research on Aging Publications

This report describes research undertaken by the Center for Social & Demographic Research on Aging (CSDRA) within the Gerontology Institute at the University of Massachusetts Boston, on behalf of the Town of Westborough. The goals of this project were to investigate the needs, interests, preferences, and opinions of Westborough’s residents age 55 or older by engaging the community regarding their experiences and needs relevant to the Council on Aging’s (COA’s) objective to identify and serve the needs of all Westborough citizens 55 and older. The contents of this report are meant to inform the Town of Westborough, the Westborough COA, …

The Effects Of Circadian Rhythm Disruption On The Behavior, Lifespan, And Fertility In Drosophila Melanogaster, Isaiah Thomas

University Honors Program Senior Projects

Circadian disruptions can have adverse behavioral and/or physiological effects on organisms, impacting their overall health and reproductive fitness. The circadian biology of Drosophila melanogaster was disrupted through exposure to excessive nighttime light. Locomotor, lifespan, and fecundity/fertility assays were used to quantify the negative effects of artificial-light-at-night (ALAN) in Oregon-R and w1118 wildtype flies. Control flies were kept in a 12:12 hr. light-dark cycle (LD) while the experimental flies were kept in a 12:12 hr. light-dim-light cycle (LDim) of 4 lux to mimic exposure to ALAN, a form of photopollution. The data showed significant behavioral differences in the active-rest phases of …

Social Media And Wellbeing, Aditya Adsule

Honors College Theses

This psychology thesis paper investigates the existing body of scientific literature surrounding the effects of social media on the wellbeing of adolescents and adults ages 18-29. The current body of scientific literature supports the overall finding that social media has a negative impact not only on mental health, but on physical health. There are also key findings showing the impact of social media on other facets of life such as sleep patterns, social interactions, and physical activity. Current intervention therapies need to be revisited and the DSM categorization of social media addiction needs to be investigated further.

Digital Literacy Among Older Adults In Singapore, Mindy Eiko Tadai, Micah Tan

ROSA Research Briefs

Singapore stands as the fourth most digitally competitive country, after Denmark, USA, and Sweden, in the latest edition of the IMD World Digital Competitiveness Ranking (IMD World Competitiveness Center, 2022). This global ranking measures the capacities of 63 nations to adopt and explore digitally transformative practices across government, industry, and wider society. Among households in Singapore, an astounding 99% have Internet access and 92% have computer access (Infocomm Media Development Authority, 2023). Even within the eldest surveyed cohort, proportions of smartphone usage have risen from 28% in 2017 to 48% in 2021 among resident Singaporeans aged 75 and above, and …

Education, Beliefs, And Health Literacy Of Care Providers On Mouth Care Of Older Adults, Molly Lakin

Honors Program: Senior Projects (Public)

Oral health is important to one’s overall health and quality of life as it can lead to chronic illnesses such as cardiovascular disease, stroke, and neurodegenerative disorders (Haumschild et al. 2021). In long-term care facilities, it is important that dependent older adults are provided mouth care to maintain their oral health and decrease their chances of developing a chronic illness; however, there are barriers affecting the level, quality, and quantity of mouth care being provided in these facilities. A survey was developed to look at the education, beliefs, and health literacy of care providers on providing mouth care in hopes …

Obstacle Crossing In Healthy Young And Older Individuals, Hope M. Hanson, Ashlyn M. Jendro, Abigail C. Schmitt

Health, Human Performance and Recreation Undergraduate Honors Theses

Introduction: In the United States, the average population age is rising and will continue to increase in the coming years.With an older population comes increased risk of injury associated with falls. Falls are considered a leading cause of injury and death in older individuals, and many falls are caused by body imbalance or obstacle collision due to a clearly visible stationary object (e.g., rug, chair, branch). Older adults tend to cross obstacles with increased toe clearance in order to prevent tripping, but much of what is known about obstacle crossing in older adults is limited to artificial obstacles that are …

Engaging Older Adults In Local Nonprofit Nutrition Assistance Programs: Understanding Barriers And Exploring Opportunities For Improved Participation, Amber R. Godinsky

Nonprofit and NGO Studies Student Projects

The rapidly growing population of older adults in the United States is set to require a highly skilled and specialized healthcare response to control the threat of a public health crisis. Research on approaches to mitigation suggests the need for an emphasis on preventative measures such as health promotion and nutrition intervention to be used as vital tools in local communities. This case study on older adults residing within DeKalb County, Illinois offers insight into the accessibility of nonprofit nutritional assistance programs by providing a local snapshot of the barriers to participation in a preventative health resource. Methods of collecting …

University Of Nebraska At Omaha Commencement: May 2023, University Of Nebraska At Omaha

Commencement Programs

No abstract provided.

Addressing The Needs Of Parkinson’S Disease Care Partners, Jenna Wall

Occupational Therapy Capstone Presentations

Parkinson’s Disease (PD) is a neurodegenerative disease that can affect all aspects of life, requiring individuals with this condition to require support from a care partner. The extensive support PD care partners provide impacts their health and well-being resulting in an increased prevalence of negative health outcomes. Furthermore, these care partners do not receive adequate support which only compiles the effect of caregiving. The main goals of this capstone project were the development and implementation of a 4-week PD care partner support protocol, the creation of an electronic resource, and improving community awareness about PD and PD care partner needs. …

The Relationships Among Proprioception, Balance, And Cognitive Perception Of Body Awareness In College Students, Courtney Helmick

Honors College Theses

Introduction: Proprioception is an important physiological function that is essential for activities of daily living as well as exercise and sport performance. Integration of proprioceptive signals plays a key role in both static and dynamic balance. Previously, researchers have assessed the relationship between balance and proprioception, however, the effect of cognitive perception of body awareness has not previously been included in this research. The aim of this pilot study was to explore the relationships among lower extremity proprioception, dynamic balance, and cognitive perception of body awareness in college students.

Methods: Nineteen apparently healthy college students (age 21.26 ± 1.10 years, …

The Impact Of Low Appendicular Skeletal Muscle Mass In The Development Of Insulin Resistance And Metabolic Syndrome: A Systematic Review Of The Literature, Ella Boston

The Eleanor Mann School of Nursing Undergraduate Honors Theses

Chronic conditions are the leading cause of death and disability. More specifically, cardio-metabolic disease is the number one cause of death worldwide. The tragedy and burden of disease is unrefuted; even more so, evidence indicates that realistic modifications of lifestyle can prevent most chronic disease. Metabolic syndrome and insulin resistance are leading risk factors in the development of cardio-metabolic disease. Presently, chronic disease is treated through symptomatic evaluation of risk. Reframing the lens of care through root cause evaluation is fundamental to optimizing patient outcomes. The purpose of this systematic review is to synthesize literature evaluating the impact of low …

The Psychometric Properties Of The Modified Fear Of Falling Avoidance Behavior Questionnaire In Parkinson’S Disease And Older Adults, Billy La, Arturo Aldaco, Ashley Haller

UNLV Theses, Dissertations, Professional Papers, and Capstones

Background/purpose: The Fear of Falling Avoidance Behavior Questionnaire (FFABQ), developed in 2011 to measure fear of falling avoidance behavior, has good evidence for reliability and validity. However, a recently modified version (mFFABQ) is theorized to be easier to understand for those completing the questionnaire because the Likert responses are more logical in completing the item stem. The purpose of this study was to examine the test-retest reliability and construct validity of the mFFABQ in adults with Parkinson’s Disease (PD) and older adults aged 60-90 years. Methods: Thirty-nine participants (age 72.21 ± 9.5; 29 men, 10 women) diagnosed with PD (diagnosis …