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Mechanically Manipulating Glymphatic Transport By Ultrasound Combined With Microbubbles, Dezhuang Ye, Si Chen, Yajie Liu, Charlotte Weixel, Zhongtao Hu, Jinyun Yuan, Hong Chen

2020-Current year OA Pubs

The glymphatic system is a perivascular fluid transport system for waste clearance. Glymphatic transport is believed to be driven by the perivascular pumping effect created by the pulsation of the arterial wall caused by the cardiac cycle. Ultrasound sonication of circulating microbubbles (MBs) in the cerebral vasculature induces volumetric expansion and contraction of MBs that push and pull on the vessel wall to generate a MB pumping effect. The objective of this study was to evaluate whether glymphatic transport can be mechanically manipulated by focused ultrasound (FUS) sonication of MBs. The glymphatic pathway in intact mouse brains was studied using …

Exploring The Hinterland: The Development Of A Person-Centered Music Therapy Method For A Hospice Patient With Lewy Body Dementia, Paige Chaplin

Expressive Therapies Capstone Theses

This thesis explores the development and implementation of a music therapy method with an individual diagnosed with dementia with Lewy Bodies (DLB) receiving home hospice services. There is very little known about the effect of music therapy on patients diagnosed with DLB. Informed by Tom Kitwood’s Person-Centered Care (PCC) philosophy for dementia care, Yumiko Sato’s Musical Life Review (MLR) model, and Lisa Kelly and Bill Ahessy’s Reminiscence-Focused Music Therapy (RFMT) model, a clinical method was developed to explore the effects of person-centered music therapy on reminiscence, caregiver connection, and identity. I drew inspiration from music therapy concepts by Tony Wigram …

Implementation Of An Implicit Bias Training In A Doctor Of Nurse Practitioner Program, Macdana Selecon

DNP Qualifying Manuscripts

Background: Implicit bias in healthcare delivery is the unconscious prejudice individuals might feel about another person or group. All healthcare providers are susceptible to implicit bias which can negatively influence patient-provider communication. Implicit bias is linked to disparities in maternal health outcomes. According to the CDC, the maternal mortality rate for non-Hispanic Black women is 2.9 times higher than the rate for non-Hispanic White women (Hoyert, 2022).

Problem: Implicit bias (IB) training is not provided in all graduate nursing programs. As a result, graduate nursing students are not prepared to manage IB during clinical rotations and post-graduation, thus, are at …

2023.05.18 - Academic/Student Affairs, Enrollment, And Technology Committee Meeting Minutes, Northeastern Illinois University Board Of Trustees

Board of Trustees - 2023

Meeting materials for the NEIU Academic/Student Affairs, Enrollment, and Technology Committee

Louisiana State University Health Sciences Center - 2023 - 149th Commencement, Office Of The Registrar, Lsu Health Sciences Center-No

Graduation & Commencement Programs

The program for the 149th Commencement of LSU Health Sciences Center - New Orleans held May 18, 2023.

Turning Strategy Into Action – Using The Echo Model To Empower The Australian Workforce To Integrate Care, Perrin Moss, Phil Nixon, Sarah Baggio, Dana Newcomb

Project ECHO Bibliography

Introduction: Children’s Health Queensland (CHQ) established a telementoring hub in Queensland, using the Project ECHO® model, to pilot and scale a range of virtual communities of practice (CoP) to empower the Australian workforce to integrate care.

Description: The establishment of the first Project ECHO hub in Queensland facilitated the implementation of a variety of child and youth health CoP that strategically aligned to the organisation’s approach to integrate care through workforce development. Subsequently, other organisations nationally have also been trained to implement and replicate the ECHO model to effect more integrated care through CoPs in other priority areas.

Discussion: Findings …

Association Of Type 2 Diabetes Subgroups With Cognitive Status Without Modification From Lifestyle Intervention, Michael P Bancks, James Lovato, Ashok Balasubramanyam, Mace Coday, Karen C Johnson, Medha Munshi, Candida Rebello, Lynne E Wagenknecht, Mark A Espeland

Faculty, Staff and Students Publications

CONTEXT: Type 2 diabetes is a risk factor for incident dementia but whether risk and treatment/prevention strategies differ by diabetes subgroup is unknown.

OBJECTIVE: We assessed (1) whether specific type 2 diabetes (T2D) subgroups are associated with mild cognitive impairment (MCI) or probable dementia (PD), and (2) whether T2D subgroups modified the association of the Action for Health in Diabetes (Look AHEAD) multidomain intensive lifestyle intervention (ILI) with MCI/PD.

METHODS: We included 3760 Look AHEAD participants with T2D and overweight or obesity randomly assigned to 10 years of ILI or diabetes support and education. We used k-means clustering techniques with …

Development Of Myelin In Wolfram Syndrome, Olga Reine Neyman

Arts & Sciences Graduate Student Theses and Dissertations

Wolfram syndrome is a rare, autosomal recessive disease traditionally characterized by juvenile onset insulin dependent diabetes, optic atrophy, deafness, and neurodegeneration often beginning in childhood and adolescence. The disease is caused by mutations in WFS1, which encodes for the protein wolframin and is associated with endoplasmic (ER) stress-mediated apoptosis. ER stress-related dysfunction may inhibit production of myelin during neurodevelopment in Wolfram syndrome, as active and developing oligodendrocytes are more vulnerable to ER stress than mature ones. It is known that white matter tracts are compromised in the disease, but many questions related to the vulnerability of myelin and its impact …

Sleep Duration Is Associated With Caudate Volume And Executive Function, Nicole Jones

Honors Theses

The ineligible role of the caudate nucleus in sleep has been implicated throughout multiple scientific studies. Previous literature has shown that greater caudate volume is associated with longer habitual sleep duration in older adults- ranging from 55 years of age and up. However, the association between sleep duration and caudate volume remains unknown in the younger population. In this study, we examined the caudate volume in youth to older adults (10 to 85 years old) with a greater sample size (N=464) to increase statistical power. The volumetric size of the caudate nucleus showed significantly positive association with habitual sleep duration, …

Commencement [Program], May 12-13, 2023, University Of Northern Iowa

UNI Commencement Programs

The program of the commencement ceremonies, including a list of institutional leadership, a list of the departments by college, awards given at the ceremonies, and a list of undergraduate and graduate degree candidates. This commencement program is not an official graduate list.

Evaluation Of The Train 2 Run Program At The Joplin Va Community Based Outpatient Clinic (Cboc), Jenifer Webb

Doctor of Nursing Practice Scholarly Project

THE EVALUATION OF A TRAIN 2 RUN PROGRAM AT THE JOPLIN VA CLINIC

An Abstract of the Scholarly Project

by Jenifer Webb, MSN, RN, FNP-C

The purpose of this project is to evaluate the effectiveness and satisfaction levels of participants in the Train 2 Run program that was started at the Joplin VA in Joplin, MO. The program was from May 3, 2022, to October 8, 2022, for a total of 5 months. The participants for this study were selected from the patients, family members, and staff who participated in the Train 2 Run program for a minimum of six …

Assessment Of Caregiver Burdens: A Screening Tool Development For The Improvement Of Caregiver Health, John M. White

Post-Professional Occupational Therapy Doctorate - Innovations in OT Symposium: Transforming Possibilities into Practice

No abstract provided.

Characterization Of Cellular Senescence In Long-Lived Birds And Mammals, Joshua Shirazi

Electronic Theses and Dissertations Archive

Cellular senescence is characterized by a permanent exit from the cell cycle and the maintenance of a very active secretome termed the senescence-associated secretory phenotype (SASP). The accumulation of senescent cells has been associated with several age-related diseases, including cancer, atherosclerosis, osteoarthritis, pulmonary fibrosis, and neurodegenerative disorders such as Alzheimer's disease. For the past two decades, cellular senescence has been intensively studied, but exclusively on laboratory rodents and human cell lines. However, our understandings about cellular senescence in other species are extremely limited. This study aimed to characterize the SASP of long-lived and short-lived species using newly developed cutting-edge proteomic …

An Investigation Into Transcription Fidelity And Its Effects On C. Elegans And S. Cerevisiae Health And Longevity, Olivia S. Dinep-Schneider

Theses and Dissertations

mRNA molecules form an intermediate in the transfer of sequences from DNA to ribosomes in order to guide protein production. Errors can be introduced into mRNA, producing aberrant proteins which place a strain on cellular regulatory machinery, causing increased risks of apoptosis, cancer, and decreased fitness. These errors may be introduced due to decreased transcriptional proofreading capabilities, exposure to chemicals, or mistakes in RNA editing machinery. It is important to investigate these causes of transcription errors to better understand the long-neglected area of mRNA fidelity which has such significant impacts on our cellular functions. In this paper, it was determined …

Anxiety, Depression, And Fear Of Dependency In Middle And Older Adults, Darby D. Mackenstadt

Theses and Dissertations

Negative stereotypes of aging, such as dependency, tend to paint a picture of older adults as frail or a burden on society. This study aimed to explore the relationship between the Fear of Dependency Scale and anxiety and depression, evaluating gender, age, and physical health as moderators. Findings suggest that age moderated the relationship between fear of dependency and depression and anxiety in women, with middle-aged women reporting the highest levels of depression and anxiety. Similarly, poor physical health in women with high fear of dependency being related to higher levels of depression and anxiety. Fear of dependency was related …

Parental Differential Treatment And Its Impact On The Sibling Relationship: A Literature Review, Kanisha Pierre-Noel

Expressive Therapies Capstone Theses

Parental differential treatment (PDT) may happen for a number of reasons. Each child is different; therefore, each child has their own individual personality and may differ developmentally or in temperament. These differences can make parenting individual children challenging. These differences can cause some parents to show preference toward one child over another because their behavior may be easier to handle. While the difference in treatment due to varying situations and developmental needs is understandable, children may still be sensitive to the increased parental attention shown to another child and be negatively affected by it. PDT explores the differences in parenting …

The Association Between Sleep And Relationship Quality Among Undergraduate Students, Catherine Smith

Honors Theses

This study sought out to examine the association between sleep and relationship quality in undergraduate student populations. Attending university is a novel experience for emerging adults but is subsequently associated with increased sleep difficulties and increased exposure to various social relationships. Indeed, the literature suggests social relationships can influence sleep in all populations, but few have explored relationship quality in the context of conflict and support in undergraduates. The quality of different social relationships (romantic, family, and friend), the severity of insomnia symptoms, and length of sleep duration were investigated. The current study collected data from a sample of ten …

Faculty Senate Agenda, Georgia Southern University, Faculty Senate

Faculty Senate Agendas

No abstract provided.

Sensor-Controlled Digital Game For Heart Failure Self-Management: Protocol For A Randomized Controlled Trial, Kavita Radhakrishnan, Christine Julien, Matthew O'Hair, Rachel Tunis, Grace Lee, Angelica Rangel, James Custer, Tom Baranowski, Paul J Rathouz, Miyong T Kim

Faculty, Staff and Students Publications

BACKGROUND: Heart failure (HF) is the leading cause of hospitalization among older adults in the United States. There are substantial racial and geographic disparities in HF outcomes, with patients living in southern US states having a mortality rate 69% higher than the national average. Self-management behaviors, particularly daily weight monitoring and physical activity, are extremely important in improving HF outcomes; however, patients typically have particularly low adherence to these behaviors. With the rise of digital technologies to improve health outcomes and motivate health behaviors, sensor-controlled digital games (SCDGs) have become a promising approach. SCDGs, which leverage sensor-connected technologies, offer the …

Socio-Emotional Resilience Among Older Adults During The Covid-19 Pandemic, Cindy J. Lahar, Angela L. Nadeau, Jayne Violette, Summer Roberts, Diana Reindl

Journal of the South Carolina Academy of Science

The detrimental impact of social isolation on health and well-being has been reported in older adults (Prohaska, et al., 2020). Yet findings also demonstrate that older adults have a motivational shift to prioritize emotionally meaningful goals and experiences (Carstensen, 1993; Sakaki, et al., 2019), prioritize emotional meaning in situations, focus on positive emotions and stimuli over negative feelings and live in the present rather than focus on future preparedness. Socioemotional selectivity theory (SST) (Carstensen, 1993; Carstensen, Fung & Charles, 2003) suggests that older adults have a limited sense of time left in life and shift their focus to meaningful and …

Academic Senate - Agenda, 5/9/2023, Academic Senate

Academic Senate Agendas

No abstract provided.

A Qualitative Multiple Case Study Of Rural Spousal Caregivers’ Experience With Health Promotion, Tamara L. Braley

Theses & Dissertations

Rural spousal caregivers caring for a person living with moderate to severe dementia at home are at risk of serious health consequences because they are unable to attend to their own personal health needs. Insufficient evidence exits that informs how contextual components of the rural spousal caregiving situation prevent caregivers from practicing personal health promotion and wellness while caregiving during the later stages of dementia. The aims of this qualitative, descriptive, multiple case study were to: 1) describe transition points in the rural spousal caregiver’s role across the dementia disease trajectory, 2) describe the rural spousal caregiver’s experience with personal …

The Exacerbating Role Of Technological And Connectivity Challenges On Older Detroiters’ Health In A Pandemic, Nicholas Schroeck, Carrie Leach

Seattle Journal of Technology, Environmental, & Innovation Law

The COVID-19 pandemic hit communities of color hard. The City of Detroit was particularly vulnerable to COVID-19 due to racial, socioeconomic, and environmental health factors. To analyze the exacerbating role of technology and connectivity challenges on older Detroiters' health in a pandemic, we first examined Detroit’s demographics. This analysis involved looking at the continued evolution of the City's population toward older adults, as well as the impact of COVID-19 and the healthcare services on Detroit’s elder population. Next, we examined Detroit’s internet access challenges, including the presence of digital exclusion among older adults in Detroit, the impact of COVID-19 on …

2023 Spring Commencement Program: Winona State University, Winona State University

WSU Commencement Programs

This is the Winona State University Spring 2023 commencement program. Commencement was on Friday, May 5, 2023.

Caring For Former Caretakers: Utilizing Collage To Explore Transition, Development Of A Method, Noelle Leblanc

Expressive Therapies Capstone Theses

Older adulthood often comes with a variety of challenges both emotional and physical. The transition to an assisted living program can be challenging to cope with. Older adults may face isolation and loneliness, while grappling with changes in their identity as result of factors like decline in health, loss of an ability, or changes in social support. Arts based interventions were administered individually among a group of older adults to test if collage could be utilized to explore themes of role shift, transition and identity. Clinical observations along with post-session reflective artwork is included. Assisted living residents participated in a …

Implementing The Timed Up And Go Test To Prevent Falls, Shamika Allen

Doctor of Nursing Practice Projects

Falls are the most reported injury within the geriatric population. Behavioral health patients have the most injurious falls, with falls impacting multiple things such as staffing, cost, injury, and quality of life for the patient (Ocker et al., 2020). Currently, the standardized fall assessment for new patients upon admission is the Morse Fall Scale (MFS). This fall assessment was intended to assess the level of fall risk for patients who are on an acute medical floor during their hospital stay. The Timed Up and Go test (TUG) is a fall assessment that has been used in geriatric patients to assess …

Introduction Of A Spinal Care Pathway Triage Protocol In The Secondary Care Setting, Tonicia I. Boston

Doctor of Nursing Practice Projects

Background: Back pain is considered the leading cause of disability worldwide. Providing effective multidisciplinary care for clients with chronic back pain (CBP) has been an ongoing issue globally. Improper care management of CBP creates personal, economic, and societal burdens that significantly affect patients, their families, and the healthcare system. Purpose: This quality improvement project aimed to successfully integrate a spinal care pathway (SCP) electronic decision support tool (e-tool) into a multidisciplinary spinal care program, to improve providers’ satisfaction with care delivery and their satisfaction with CBP patient outcomes. Methods: This DNP project used an evidence-based quality improvement (EBQI) design to …

Emotion-Focused Dyadic Coping Styles Used By Family Carers Of People With Dementia During The Covid-19 Pandemic, C Colclough, E Miles, J Rusted, R Perach, Et Al

Peninsula Medical School

Emotional wellbeing of family carers and people with dementia is associated with not only how each individual copes with stress and conflict, but also by how they cope together. Finding ways to positively cope together was particularly important during COVID-19 lockdown restrictions, when other avenues of emotional support were less available. We explored how carers experienced and used emotion-focused dyadic coping styles during the COVID-19 pandemic. In-depth qualitative interviews were conducted during the pandemic with 42 family carers, supplemented by quality of life scores collected both pre- and during the pandemic and household status. Abductive thematic analysis identified five styles …

Board Of Trustees Agenda, May 5 2023, Indiana State University Board Of Trustees

Board of Trustees

No abstract provided.

Older Adult Aerobic Capacity, Muscular Strength, Fitness And Body Composition After 20+ Years Of Exercise Training: A Systematic Review And Meta-Analysis, Eric Leslie, Vincent Luna, Ann L. Gibson

International Journal of Exercise Science

International Journal of Exercise Science 16(3): 620-637, 2023. Older adults (³ 65 years) are recommended to participate in regular exercise to maintain health in late adulthood. The impact of long-term (20+ years) exercise training that align with the American College of Sports Medicine’s (ACSM) recommended guidelines has not been evaluated for older adults. To address this, a systematic review and meta-analyses were performed regarding the effects of long-term exercise training on older adult aerobic capacity, muscular fitness, and body composition that meet the ACSM’s recommendation for weekly training volume. Ten studies with individuals that performed cardiorespiratory or resistance exercise met …