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2023

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Lower Body Joint Moments During The Golf Swing In Older Adults: Comparison To Other Activities Of Daily Living, Scott K. Lynn, Junsig Wang, Abigail C. Schmitt, C. Lowry Barnes Sep 2023

Lower Body Joint Moments During The Golf Swing In Older Adults: Comparison To Other Activities Of Daily Living, Scott K. Lynn, Junsig Wang, Abigail C. Schmitt, C. Lowry Barnes

Health, Human Performance and Recreation Faculty Publications and Presentations

Golf participation has increased dramatically in the last several years. With this increase in participation, clinicians need better evidenced based strategies to advise those golfers with different pathologies when it is safe to return to the game. Golf teaching professionals also need to understand how to alter golf mechanics to protect injured and/or diseased joints in golfers to allow them to play pain free and avoid further injury. This study used a 3-dimensional link segment model to calculate the net joint moments on the large lower limb joints (knee and hip) during golf (lead and trail leg) and two commonly …


Life’S Essential 8: Optimizing Health In Older Adults, Manish Kumar, Ariela Orkaby, Caitlan Tighe, Dennis T Villareal, Hayley Billingsley, Michael G Nanna, Min Ji Kwak, Namit Rohant, Shreya Patel, Parag Goyal, Scott Hummel, Christina Al-Malouf, Amie Kolimas, Ashok Krishnaswami, Mike W Rich, James Kirkpatrick, Abdulla A Damluji, George A Kuchel, Daniel E Forman, Karen P Alexander Sep 2023

Life’S Essential 8: Optimizing Health In Older Adults, Manish Kumar, Ariela Orkaby, Caitlan Tighe, Dennis T Villareal, Hayley Billingsley, Michael G Nanna, Min Ji Kwak, Namit Rohant, Shreya Patel, Parag Goyal, Scott Hummel, Christina Al-Malouf, Amie Kolimas, Ashok Krishnaswami, Mike W Rich, James Kirkpatrick, Abdulla A Damluji, George A Kuchel, Daniel E Forman, Karen P Alexander

Faculty, Staff and Student Publications

The population worldwide is getting older as a result of advances in public health, medicine, and technology. Older individuals are living longer with a higher prevalence of subclinical and clinical cardiovascular disease (CVD). In 2010, the American Heart Association introduced a list of key prevention targets, known as "Life's Simple 7" to increase CVD-free survival, longevity, and quality of life. In 2022, sleep health was added to expand the recommendations to "Life's Essential 8" (eat better, be more active, stop smoking, get adequate sleep, manage weight, manage cholesterol, manage blood pressure, and manage diabetes). These prevention targets are intended to …


Acceptance Of Communication Technology, Emotional Support And Subjective Well-Being For Chinese Older Adults Living Alone During Covid-19: A Moderated Mediation Model, Ze Ling Nai, Woan Shin Tan, William Tov Sep 2023

Acceptance Of Communication Technology, Emotional Support And Subjective Well-Being For Chinese Older Adults Living Alone During Covid-19: A Moderated Mediation Model, Ze Ling Nai, Woan Shin Tan, William Tov

Research Collection School of Social Sciences

Stringent social distancing measures implemented to control the spread of COVID-19 affected older adults living alone by limiting their social interaction beyond their households. During these restrictions, interactions beyond the household could be facilitated by communication technology (CT) such as voice calls, instant messages. Our study provides evidence on how CT acceptance could influence the emotional support and in turn, subjective well-being (SWB) of older adults living alone. We did a cross-sectional survey with 293 community-dwelling Chinese older adults. Participants were surveyed from September to November 2020 and had completed measures on CT acceptance (competency), emotional support, and SWB. PROCESS …


Process And Structure: Service Satisfaction And Recommendation In A Community-Based Elderly Meal Service In Shanghai, Lin Chen, Minzhi Ye, Eva Kahana Sep 2023

Process And Structure: Service Satisfaction And Recommendation In A Community-Based Elderly Meal Service In Shanghai, Lin Chen, Minzhi Ye, Eva Kahana

School of Social Work Faculty Publications

Informed by Donabedian’s quality-of-care framework, this study aims to examine elderly clients’ service satisfaction and service recommendation for community-based meal services in Shanghai. We analyzed secondary survey data from randomly sampled elderly clients of a community-based meal service in the old Jing’an District in Shanghai (N= 690). Quality of food and caregivers’ attitudes were key to respondents’ service recommendation while tidiness of tableware and interactions with caregivers were positively related to their service satisfaction. Overlaps and differences between structure and process factors are discussed. We also provide tailored policy recommendations.


Clinical & Laboratory Markers As Predictors For Severity And Mortality In Covid-19, Asma Ameen Ghareeb, Sazan Moffaq Abdulaziz Sep 2023

Clinical & Laboratory Markers As Predictors For Severity And Mortality In Covid-19, Asma Ameen Ghareeb, Sazan Moffaq Abdulaziz

Polytechnic Journal

Backgrounds: COVID-19, a new health challenge, can be diagnosed by many laboratory biomarkers. Biomarkers became valuable for prognosis; identifying the severity and mortality of the disease in COVID-19 patients. This study aims to determine the association of clinical, demographics, and laboratory biomarkers (CRP, D-dimer, lymphocyte, and platelet) with the severity and mortality of COVID-19. Methods: Between June 1st and November 1st, 2020, 34 healthy controls and 104 COVID-19 cases were enrolled in this study. SARS-CoV-2 infection was confirmed using the real-time RT-PCR technique. All cases were analyzed for clinical, epidemiological, and laboratory biomarkers. COVID-19 cases were regrouped into mild (n=40), …


Perceptions Of Islamic Banking Among Post Millennials: A Study On Muslim Students, Aysa Siddika, Abdullah Sarwar, Fouzia Khan Aug 2023

Perceptions Of Islamic Banking Among Post Millennials: A Study On Muslim Students, Aysa Siddika, Abdullah Sarwar, Fouzia Khan

International Journal of Management, Finance and Accounting

This study aimed to understand the perception of Islamic banking among post millennials Muslim students and explore their expectations towards Islamic Shariah compliant banking. The study uses qualitative method to understand respondents’ subjective views. Semi-structured interviews are used among the Muslim students studying at public and private universities in Malaysia. Twelve students were selected using purposive sampling. The analysis revealed that religious motives, efficient services, and convenience in terms of online banking and ATM services are factors in bank selection. The study found that the students’ perceptions of their understanding of Islamic banking are not sufficient, and there is a …


(2011) Grandparents Raising Grandchildren: The Effects, Counseling Challenges, And Strategies, Harriet A. Bachner Aug 2023

(2011) Grandparents Raising Grandchildren: The Effects, Counseling Challenges, And Strategies, Harriet A. Bachner

Louisiana Journal of Counseling

For more than 20 years the number of grandparents who have taken over the role of the primary custodial caregiver of their grandchildren has steadily increased. There has been burgeoning investigation and interest into this phenomenon that affects the largest segment of the U.S. population, the baby boom generation, as well as older adults. This report provides an overview of the most critical issues that have been covered in the literature and identifies some of the challenges for counselors who work with both the grandparents and the children. Some counseling strategies that have been shown to be promising in dealing …


An Update On The Healthy Soldier Effect In U.S. Veterans, Erin Sullivan-Baca, Rizwana Rehman, Zulfi Haneef Aug 2023

An Update On The Healthy Soldier Effect In U.S. Veterans, Erin Sullivan-Baca, Rizwana Rehman, Zulfi Haneef

Faculty, Staff and Students Publications

Introduction: The healthy soldier effect (HSE) describes a phenomenon of enduring health and lower mortality among veterans due in part to initial screening procedures and health care access. Although early data were supportive of a broad HSE among former military members, more recent investigations have suggested a possible attenuation of the effect with older age. The present study aimed to provide an update of the HSE using an expansive Veterans Health Administration (VHA)-wide sample with a particular focus on age and sex effects.

Materials and methods: Mortality data for veterans within the VHA were obtained from the VHA Support Service …


Indonesia And Malaysia Students’ Quality Of Life After The Covid-19 Pandemic: A Mixed Methods Study, Juster Juster Sinaga, Mawaddah Sarif, Siti Aishah Hassan Aug 2023

Indonesia And Malaysia Students’ Quality Of Life After The Covid-19 Pandemic: A Mixed Methods Study, Juster Juster Sinaga, Mawaddah Sarif, Siti Aishah Hassan

Jurnal Kajian Bimbingan dan Konseling

Learning from home during the COVID-19 pandemic and learning face-to-face at school with strict health protocols during the COVID-19 pandemic have long-term negative effects on the psychological health of students. This situation may impact life quality (QoL). To measure students’ quality of life, mixed methods were adopted. Participants in this research ranged in age from 12 to 19 years. The study involved a total of 139 research participants. Kidscreen-27 questionnaires with a reliability coefficient of 0.913 percent were used. The interviews were conducted according to a set of defined rules. This data was collected online. The analysis was quantitative, qualitative, …


Biomechanical Analysis Of Muscle Balance Between The Dominant And Non-Dominant Legs Among Jordanian National Team Players Practicing The Back Squat Exercise, Iyad Abu Touq, Osama Abdel Fattah, Khaled Atiyat Aug 2023

Biomechanical Analysis Of Muscle Balance Between The Dominant And Non-Dominant Legs Among Jordanian National Team Players Practicing The Back Squat Exercise, Iyad Abu Touq, Osama Abdel Fattah, Khaled Atiyat

Jordan Journal of Applied Science-Humanities Series

This study aimed to identify the values of some biomechanical variables of the muscles operating at the pelvic, knee, and ankle joints in the dominant and non-dominant legs among Jordanian national team players practicing the back squat exercise using the Biodex device. Additionally, it sought to examine the differences in the values of the biomechanical variables between the dominant and non-dominant legs. To achieve this, the researchers employed a descriptive approach, selecting a sample of 15 males chosen through purposive sampling, ensuring their training included squat exercises for a period of no less than two years. The researchers used the …


(2016) Pharmacology Training Of Counselors, Jessica Fanguy Cortez, Chris Rachal Aug 2023

(2016) Pharmacology Training Of Counselors, Jessica Fanguy Cortez, Chris Rachal

Louisiana Journal of Counseling

As the use of psychotropic medications to treat mental illness increases across the lifespan, the need for psychopharmacology training for counselors intensifies. Research by Sepulveda (2011) concluded that counselor educators are not overwhelmingly supportive of including a psychopharmacology course in CACREP–approved school counselor curricula. Expanding on Sepulveda’s (2011) work, our findings indicate that most CACREP-approved counseling programs do not offer psychological or psychopharmacology courses. Most program directors favor such courses in their programs, and agree that licensed counselors are routinely confronted with medication issues in professional settings. But despite the fact that most programs lack training in psychopharmacology, directors believe …


Sleep, Nutrition, Hydration And Rest: The Equal Importance Of External Factors Outside Of Training And Practice For Sports Injury Prevention, Troy B. Puga, Rishabh M. Mazumder, Tiffany Ruan, Nicholas Scigliano, Grace Thiel, Kevin Treffer Aug 2023

Sleep, Nutrition, Hydration And Rest: The Equal Importance Of External Factors Outside Of Training And Practice For Sports Injury Prevention, Troy B. Puga, Rishabh M. Mazumder, Tiffany Ruan, Nicholas Scigliano, Grace Thiel, Kevin Treffer

Student Publications

Training and practice preparation have long received attention as the largest factors for injury prevention. While proper training and practice programs are a crucial component of injury prevention, they only represent a piece of a larger puzzle. External factors outside of training and practice such as sleep, nutrition, hydration, and rest are equally important for injury prevention due to athletes spending a majority of their day outside of their sport. These external factors have been shown to have powerful effects relating to injury epidemiology. They have also been shown to have major effects on the body’s autonomic and hormonal regulation …


Abdominal Aortic Calcification, Bone Mineral Density And Fractures: A Systematic Review And Meta-Analysis Of Observational Studies, Abadi K. Gebre, Joshua R. Lewis, Kevin Leow, Pawel Szulc, David Scott, Peter R. Ebeling, Marc Sim, Germaine Wong, Wai H. Lim, John T. Schousboe, Douglas P. Kiel, Richard L. Prince, Alexander J. Rodriguez Aug 2023

Abdominal Aortic Calcification, Bone Mineral Density And Fractures: A Systematic Review And Meta-Analysis Of Observational Studies, Abadi K. Gebre, Joshua R. Lewis, Kevin Leow, Pawel Szulc, David Scott, Peter R. Ebeling, Marc Sim, Germaine Wong, Wai H. Lim, John T. Schousboe, Douglas P. Kiel, Richard L. Prince, Alexander J. Rodriguez

Research outputs 2022 to 2026

Background: Abdominal aortic calcification (AAC) has been inconsistently associated with skeletal health. We aimed to investigate the association of AAC with bone mineral density (BMD) and fracture risk by pooling the findings of observational studies. Methods: MEDLINE, EMBASE, Web of Science, and Google Scholar were searched (August 2021). All clinical studies that assessed the association between AAC and BMD or fracture were included. AAC was categorized into any/advanced (all higher reported groups) versus no/less advanced (lowest reported group). Pooled standardized mean differences (SMDs) and risk ratios (RRs) with 95% confidence intervals (CI) were determined for BMD and fracture, respectively, using …


The Cajun Traiteurs, Shelby Kathleen Robert Aug 2023

The Cajun Traiteurs, Shelby Kathleen Robert

Doctoral Dissertations and Projects

Traiteurs are traditional folk medicine healers who are a part of the culture of the Cajuns of Louisiana. These people are believed to possess special healing powers given to them by God. They are a significant part of the lifestyle and traditional culture of the Cajuns. The Cajuns are the descendants of the Acadians, a group of French colonists who were forcibly removed from Nova Scotia and dispersed all over North America by the British in 1755. Though the Acadians were able to partially reassemble themselves in Louisiana, they still faced great adversity within the state. This project examines the …


Human Needs: Overview, Michael A. Dover Aug 2023

Human Needs: Overview, Michael A. Dover

Social Work Faculty Publications

Human need and related concepts such as basic needs have long been part of the implicit conceptual foundation for social work theory, practice, and research. However, although the published literature in social work has long stressed social justice, and has incorporated discussion of human rights, human need has long been both a neglected and contested concept. In recent years, the explicit use of human needs theory has begun to have a significant influence on the literature in social work.


Sociocultural Factors Associated With Persistent Prescription Opioid Use (Ppou) Among Puerto Rican Adults In Massachusetts, Inyene E. Essien-Aleksi, Yuan Zhang, Ainat Koren, Natalia Palacios, Luis M. Falcon, Katherine L. Tucker Aug 2023

Sociocultural Factors Associated With Persistent Prescription Opioid Use (Ppou) Among Puerto Rican Adults In Massachusetts, Inyene E. Essien-Aleksi, Yuan Zhang, Ainat Koren, Natalia Palacios, Luis M. Falcon, Katherine L. Tucker

Health Sciences Faculty Publications

Background: Increasing numbers of opioid-overdose deaths have been witnessed among Hispanics and other underserved populations in Massachusetts. Puerto Rican adults (PRs) have a disproportionately higher prevalence of chronic diseases than non-Hispanic White adults-conditions linked to increased prescription opioid use and misuse. Stress indicators, including low acculturation, low social support, and perceived discrimination, have been recognized as correlates of chronic diseases. However, little research has been undertaken on how these socio-cultural factors relate to persistent prescription opioid use among PRs. This study evaluated the prevalence of prescription opioid use and socio-cultural factors associated with persistent prescription opioid use among PRs.

Methods: …


Radioprotective Effects Of Melatonin And Thymoquinone On Liver, Parotid Gland, Brain, And Testis Of Rats Exposed To Total Body Irradiation, Mehmet Koç, Çi̇ğdem Damla Deni̇z, Mehmet Aki̇f Eryilmaz, Yilmaz Tezcan, Mehmet Gürbi̇lek Aug 2023

Radioprotective Effects Of Melatonin And Thymoquinone On Liver, Parotid Gland, Brain, And Testis Of Rats Exposed To Total Body Irradiation, Mehmet Koç, Çi̇ğdem Damla Deni̇z, Mehmet Aki̇f Eryilmaz, Yilmaz Tezcan, Mehmet Gürbi̇lek

Turkish Journal of Medical Sciences

Background/aim: This study aimed to investigate thymoquinone (TQ), and melatonin's radioprotective effects on liver, parotid gland, brain, and testis of rats which were exposed to total body irradiation (IR). Materials and methods: Thirty adult Wistar rats were randomly divided into four groups that are Group 1 (control group): total body IR only, Group 2: IR-Melatonin (10 mg/kg), Group 3: IR-TQ (10 mg/kg), and Group 4 (sham group): nothing. Total body IR dose was 6 Gy. Tissue samples were taken 90 min after IR. The measurements of malondialdehyde (MDA), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD) were performed in all groups. …


Impact Of 10-Week Evidence–Based Falls Prevention Program On Outcomes Related To Falls Risk In Community-Dwelling Older Adults, Mark A. Schafer, Paula Upright, Jana Michalik, K. Jason Crandall Aug 2023

Impact Of 10-Week Evidence–Based Falls Prevention Program On Outcomes Related To Falls Risk In Community-Dwelling Older Adults, Mark A. Schafer, Paula Upright, Jana Michalik, K. Jason Crandall

International Journal of Exercise Science

International Journal of Exercise Science 16(7): 1131-1141, 2023. This quasi-experimental study evaluated the impact of a 10-week evidence-based falls prevention program (Bingocize®) on self-reported fear of falling, general health, physical activity, social isolation, and avoidance behavior, in community-dwelling older adults in Virginia. Participants > 60 years of age (n= 481) attended Bingocize® group sessions twice per week for 10 weeks. The program combined conventional bingo with periodic strength, balance, flexibility exercises, and fall prevention education. Pre and post assessments gauged participants' self-perception of fear of falling, general health, physical activity, social isolation, and avoidance behavior. 481 participants attended at least 80% …


Designing Social Connection: Older Adults And The Infrastructure Of Social Encounters, Bomin Kim Aug 2023

Designing Social Connection: Older Adults And The Infrastructure Of Social Encounters, Bomin Kim

Graduate School of Architecture & Urban Design Theses & Dissertations

In recent decades, public space has gained significant attention in both design theory and practice as a critical components of sustainable development for older adults. With growing concerns about social disconnect, economic inequality, and environmental injustice, the revitalization of public space has become a critical piece in creating safe and just cities to foster social connection, health, and resilience for our aging population. I argue in this dissertation that older adults rely on an infrastructure of encounters to navigate social life and that designers and policymakers should critically examine how public spaces distribute and burden labor necessary to create weak …


Beyond Economics And Politics : A Sociological Review Of Local Long-Term Care Service Provision In China, Zhen Tian Aug 2023

Beyond Economics And Politics : A Sociological Review Of Local Long-Term Care Service Provision In China, Zhen Tian

Lingnan Theses (MPhil & PhD)

The socio-demographic transition presents a significant challenge that impacts the renewal of welfare arrangements and the reallocation of welfare responsibilities across sectors. Long-term care (LTC) services have emerged as a widely accepted strategy to promote the active daily living and human dignity of senior citizens. This study aims to assess the effective policy strategies employed in various Chinese contexts to address significant LTC policy concerns and synthesise lessons that can guide future policy decisions. The study addresses three questions to explore local variations in China's LTC service provision: (1) What differences exist in the long-term care services provision? (2) How …


Enigma Chek2gether Project: A Comprehensive Study Identifies Functionally Impaired Chek2 Germline Missense Variants Associated With Increased Breast Cancer Risk, Lenka Stolarova, Petra Kleiblova, Petra Zemankova, Barbora Stastna, Marketa Janatova, Jana Soukupova, Maria Isabel Achatz, Christine Ambrosone, Paraskevi Apostolou, Banu K Arun, Paul Auer, Mollie Barnard, Birgitte Bertelsen, Biobank Japan, Marinus J Blok, Nicholas Boddicker, Joan Brunet, Elizabeth S Burnside, Mariarosaria Calvello, Ian Campbell, Sock Hoai Chan, Fei Chen, Jian Bang Chiang, Anna Coppa, Laura Cortesi, Ana Crujeiras-González, Consortium Czecanca, Kim De Leeneer, Robin De Putter, Allison Depersia, Lisa Devereux, Susan Domchek, Anna Efremidis, Christoph Engel, Corinna Ernst, D Gareth R Evans, Lidia Feliubadaló, Florentia Fostira, Olivia Fuentes-Ríos, Encarna B Gómez-García, Sara González, Christopher Haiman, Thomas Van Overeem Hansen, Jan Hauke, James Hodge, Chunling Hu, Hongyan Huang, Nur Diana Binte Ishak, Yusuke Iwasaki, Irene Konstantopoulou, Peter Kraft, James Lacey, Conxi Lázaro, Na Li, Weng Khong Lim, Sara Lindstrom, Adriana Lori, Elana Martinez, Alexandra Martins, Koichi Matsuda, Giuseppe Matullo, Simone Mcinerny, Kyriaki Michailidou, Marco Montagna, Alvaro N A Monteiro, Luigi Mori, Katherine Nathanson, Susan L Neuhausen, Heli Nevanlinna, Janet E Olson, Julie Palmer, Barbara Pasini, Alpa Patel, Maria Piane, Bruce Poppe, Paolo Radice, Alessandra Renieri, Nicoletta Resta, Marcy E Richardson, Toon Rosseel, Kathryn J Ruddy, Marta Santamariña, Elizabeth Santana Dos Santos, Lauren Teras, Amanda E Toland, Amy Trentham-Dietz, Celine M Vachon, Alexander E Volk, Nana Weber-Lassalle, Jeffrey N Weitzel, Lisa Wiesmuller, Stacey Winham, Siddhartha Yadav, Drakoulis Yannoukakos, Song Yao, Valentina Zampiga, Magnus Zethoven, Ze Wen Zhang, Tomas Zima, Amanda B Spurdle, Ana Vega, Maria Rossing, Jesús Del Valle, Arcangela De Nicolo, Eric Hahnen, Kathleen B M Claes, Joanne Ngeow, Yukihide Momozawa, Paul A James, Fergus J Couch, Libor Macurek, Zdenek Kleibl Aug 2023

Enigma Chek2gether Project: A Comprehensive Study Identifies Functionally Impaired Chek2 Germline Missense Variants Associated With Increased Breast Cancer Risk, Lenka Stolarova, Petra Kleiblova, Petra Zemankova, Barbora Stastna, Marketa Janatova, Jana Soukupova, Maria Isabel Achatz, Christine Ambrosone, Paraskevi Apostolou, Banu K Arun, Paul Auer, Mollie Barnard, Birgitte Bertelsen, Biobank Japan, Marinus J Blok, Nicholas Boddicker, Joan Brunet, Elizabeth S Burnside, Mariarosaria Calvello, Ian Campbell, Sock Hoai Chan, Fei Chen, Jian Bang Chiang, Anna Coppa, Laura Cortesi, Ana Crujeiras-González, Consortium Czecanca, Kim De Leeneer, Robin De Putter, Allison Depersia, Lisa Devereux, Susan Domchek, Anna Efremidis, Christoph Engel, Corinna Ernst, D Gareth R Evans, Lidia Feliubadaló, Florentia Fostira, Olivia Fuentes-Ríos, Encarna B Gómez-García, Sara González, Christopher Haiman, Thomas Van Overeem Hansen, Jan Hauke, James Hodge, Chunling Hu, Hongyan Huang, Nur Diana Binte Ishak, Yusuke Iwasaki, Irene Konstantopoulou, Peter Kraft, James Lacey, Conxi Lázaro, Na Li, Weng Khong Lim, Sara Lindstrom, Adriana Lori, Elana Martinez, Alexandra Martins, Koichi Matsuda, Giuseppe Matullo, Simone Mcinerny, Kyriaki Michailidou, Marco Montagna, Alvaro N A Monteiro, Luigi Mori, Katherine Nathanson, Susan L Neuhausen, Heli Nevanlinna, Janet E Olson, Julie Palmer, Barbara Pasini, Alpa Patel, Maria Piane, Bruce Poppe, Paolo Radice, Alessandra Renieri, Nicoletta Resta, Marcy E Richardson, Toon Rosseel, Kathryn J Ruddy, Marta Santamariña, Elizabeth Santana Dos Santos, Lauren Teras, Amanda E Toland, Amy Trentham-Dietz, Celine M Vachon, Alexander E Volk, Nana Weber-Lassalle, Jeffrey N Weitzel, Lisa Wiesmuller, Stacey Winham, Siddhartha Yadav, Drakoulis Yannoukakos, Song Yao, Valentina Zampiga, Magnus Zethoven, Ze Wen Zhang, Tomas Zima, Amanda B Spurdle, Ana Vega, Maria Rossing, Jesús Del Valle, Arcangela De Nicolo, Eric Hahnen, Kathleen B M Claes, Joanne Ngeow, Yukihide Momozawa, Paul A James, Fergus J Couch, Libor Macurek, Zdenek Kleibl

Faculty, Staff and Student Publications

PURPOSE: Germline pathogenic variants in CHEK2 confer moderately elevated breast cancer risk (odds ratio, OR ∼ 2.5), qualifying carriers for enhanced breast cancer screening. Besides pathogenic variants, dozens of missense CHEK2 variants of uncertain significance (VUS) have been identified, hampering the clinical utility of germline genetic testing (GGT).

EXPERIMENTAL DESIGN: We collected 460 CHEK2 missense VUS identified by the ENIGMA consortium in 15 countries. Their functional characterization was performed using CHEK2-complementation assays quantifying KAP1 phosphorylation and CHK2 autophosphorylation in human RPE1-CHEK2-knockout cells. Concordant results in both functional assays were used to categorize CHEK2 VUS from 12 ENIGMA case-control datasets, including …


Motor Satisfaction And Its Relationship To Quality Of Life Among Physically Active Elderly Women, Reem Al-Huniti Aug 2023

Motor Satisfaction And Its Relationship To Quality Of Life Among Physically Active Elderly Women, Reem Al-Huniti

Jordan Journal of Applied Science-Humanities Series

This study aimed to identify the relationship between the level of motor satisfaction and quality of life among elderly women who engage in physical activities. The study sample consisted of 25 women practicing physical activities at Al-Hussein Sports City, with an average age of 63.1 years. A descriptive approach was used, with the Motor Satisfaction Scale (Allawi, 1998) and the Quality of Life (QOL) Scale (WHOQOL-BREF) developed by the World Health Organization (1998). The results indicated a positive statistically significant relationship at the alpha level of α ≤ 0.05 between motor satisfaction and the dimensions of quality of life for …


Dna Methylation Networks Underlying Mammalian Traits, Amin Haghani Aug 2023

Dna Methylation Networks Underlying Mammalian Traits, Amin Haghani

Department of Animal Science: Faculty Publications

INTRODUCTION: Comparative epigenomics is an emerging field that combines epigenetic signatures with phylogenetic relationships to elucidate species characteristics such as maximum life span. For this study, we generated cytosine DNA methylation (DNAm) profiles (n = 15,456) from 348mammalian species using amethylation array platform that targets highly conserved cytosines.

RATIONALE: Nature has evolved mammalian species of greatly differing life spans. To resolve the relationship ofDNAmwith maximum life span and phylogeny, we performed a largescale cross-species unsupervised analysis. Comparative studies in many species enables the identification of epigenetic correlates of maximum life span and other traits.

RESULTS: We …


Closure Of Nursing Homes In Rural Texas During 2022-2023 A Three-County Case Study, Johanne Wadsworth Aug 2023

Closure Of Nursing Homes In Rural Texas During 2022-2023 A Three-County Case Study, Johanne Wadsworth

MUSC Theses and Dissertations

The COVID-19 pandemic has had a profound impact on the healthcare system, particularly for nursing homes. In this study, the impact of the acute 2022 epidemic on the closure of nursing homes in rural Texas was examined. The objective was to identify the factors that contributed to the closure of these nursing homes during the epidemic which eventually led to limited bed availability and closures over an 11-month period. Data was collected on the number of nursing homes that closed, their location, and the reasons for closure. The target. Criteria for measuring adequate bed availability was Based on review of …


Fall Risk Identification And Reduction Among The Gerontological Population At A Long-Term Care Facility, Esther A. Lowe, Breanna Cates, Lisa James, Ashley Samson, Jowel Ochoa, Matthew Ng Aug 2023

Fall Risk Identification And Reduction Among The Gerontological Population At A Long-Term Care Facility, Esther A. Lowe, Breanna Cates, Lisa James, Ashley Samson, Jowel Ochoa, Matthew Ng

Master's Projects and Capstones

Abstract

Problem: Data obtained from the facility from February 2022 to July 2023 showed that there were a total of 110 falls at the facility with 51% resulting in injury. The facility also lacked a standardized fall assessment tool with minimal follow up after fall incidents.

Context: A microsystem assessment of the geriatric population at the long-term care facility indicated the need for a standardized fall risk screening tool to accurately assess patients.

Interventions: A staff presentation was created highlighting the high rate of falls at the facility as well as to educate on the implementation of the Morse Fall …


The Effects Of Elevation And Soaking Conditions On Dry Bean Cooking Time, Chelsea Didinger, Karen Cichy, Carlos Urrea, Madalyn Scanlan, Henry Thompson Aug 2023

The Effects Of Elevation And Soaking Conditions On Dry Bean Cooking Time, Chelsea Didinger, Karen Cichy, Carlos Urrea, Madalyn Scanlan, Henry Thompson

Panhandle Research and Extension Center

Dry beans and other pulses (e.g., chickpeas and cowpeas) are nutrient-dense foods that promote human and environmental health. However, consumption is declining in many regions around the world. Addressing barriers to greater pulse intake is important to reverse this trend. Cooking time is one such barrier, with consumers viewing the long cooking times of many pulses as a hurdle to higher consumption due to lack of time or fuel availability. Equipping consumers with simple, accessible ways to reduce pulse cooking time is one way to mitigate this barrier. Accordingly, this study assessed changes to cooking time when pinto beans ( …


Apolipoprotein-Ε4 Is Associated With Higher Fecundity In A Natural Fertility Population, Benjamin Trumble, Mia Charifson, Tom Kraft, Angela R. Garcia, Daniel K. Cummings, Paul L. Hooper, Amanda J. Lea, Daniel Eid Rodriguez, Stephanie V. Koebele, Kenneth Buetow, Bret Beheim, Riana Minocher, Maguin Gutierrez, Gregory S. Thomas, Margaret Gatz, Jonathan Stieglitz, Caleb E. Finch, Hillard Kaplan, Michael Gurven Aug 2023

Apolipoprotein-Ε4 Is Associated With Higher Fecundity In A Natural Fertility Population, Benjamin Trumble, Mia Charifson, Tom Kraft, Angela R. Garcia, Daniel K. Cummings, Paul L. Hooper, Amanda J. Lea, Daniel Eid Rodriguez, Stephanie V. Koebele, Kenneth Buetow, Bret Beheim, Riana Minocher, Maguin Gutierrez, Gregory S. Thomas, Margaret Gatz, Jonathan Stieglitz, Caleb E. Finch, Hillard Kaplan, Michael Gurven

ESI Publications

In many populations, the apolipoprotein-ε4 (APOE-ε4) allele increases the risk for several chronic diseases of aging, including dementia and cardiovascular disease; despite these harmful effects at later ages, the APOE-ε4 allele remains prevalent. We assess the impact of APOE-ε4 on fertility and its proximate determinants (age at first reproduction, interbirth interval) among the Tsimane, a natural fertility population of forager-horticulturalists. Among 795 women aged 13 to 90 (20% APOE-ε4 carriers), those with at least one APOE-ε4 allele had 0.3 to 0.5 more children than (ε3/ε3) …


The Minutes Of The Marshall University Board Of Governors Meeting, August 8, 2023, Marshall University Board Of Governors Aug 2023

The Minutes Of The Marshall University Board Of Governors Meeting, August 8, 2023, Marshall University Board Of Governors

Board of Governors Minutes

No abstract provided.


Ten Questions Concerning Smart And Healthy Built Environments For Older Adults, Sanjay Kumar, Samuel H. Underwood, Julie L. Masters, Natalie A. Manley, Iason Konstantzos, Josephine Lau, Ryan Haller, Lily M. Wang Aug 2023

Ten Questions Concerning Smart And Healthy Built Environments For Older Adults, Sanjay Kumar, Samuel H. Underwood, Julie L. Masters, Natalie A. Manley, Iason Konstantzos, Josephine Lau, Ryan Haller, Lily M. Wang

Durham School of Architectural Engineering and Construction: Faculty Publications

In the past decade, the term ‘global aging’ has gained much attention among researchers, policymakers, civil societies, and governments worldwide. The continuous decline in fertility rates and increased life expectancy have resulted in an ongoing demographic transition where the share of adults aged 65 or older is increasing and outnumbering children younger than five years. In the United States and other developed countries, this rapid demographic transition is expected to continue to strain the existing health infrastructure as it becomes increasingly challenging to ensure healthy living environments for older adults. The ten questions and answers in this paper have been …


Reduce Extended Length Of Stay By Reducing In-Hospital Falls, Norberto Benitez Aug 2023

Reduce Extended Length Of Stay By Reducing In-Hospital Falls, Norberto Benitez

Master's Projects and Capstones

Abstract

Problem: Every year, there are many in-hospital falls (IHFs). Nationally there are between 700,000 to 1 million falls recorded each year. Hospital falls financially burden our healthcare industry, costing approximately 34 billion annually. Context: In a local hospital in Northern California, Marin County, the microsystem has had an extraordinary number of in-hospital falls (IHFs). To date (June 2023), 13 falls have been recorded thus far; the microsystem is on track to beat the previous year's record number of 21 falls in a calendar year. Interventions: The MSN–CNL student proposed re-educating staff, resetting expectations, and reestablishing workflow. We also sought …