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2023

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Goal-Directed Haemodynamic Therapy Improves Patient Outcomes In Kidney Transplantation, J Fabes, Midani A Al, As Sarna, Dh Hadi, Sa Naji, Nr Banga, Gl Jones, Pd Berry, Md Wittenberg Jan 2023

Goal-Directed Haemodynamic Therapy Improves Patient Outcomes In Kidney Transplantation, J Fabes, Midani A Al, As Sarna, Dh Hadi, Sa Naji, Nr Banga, Gl Jones, Pd Berry, Md Wittenberg

Peninsula Medical School

Introduction: Kidney transplant graft function depends on optimised haemodynamics. However, high fluid volumes risk hypervolaemic complications. The Edwards Lifesciences ClearSight™ device permits fluid titration through markers of preload and beat-to-beat blood pressure monitoring. We evaluated the implementation of a novel goal-directed haemodynamic therapy protocol to determine whether patient outcomes had improved. Design: A retrospective evaluation of standard care versus goal-directed haemodynamic therapy in adults undergoing kidney transplantation was performed in a single centre between April 2016 and October 2019. Twenty-eight standard-of-care patients received intraoperative fixed-rate infusion and 28 patients received goal-directed haemodynamic therapy. The primary outcome was volume of fluid …


Climate Action And Sdg Synergies: Strengthening The Evidence Base For Synergistic Action, Souran Chatterjee Jan 2023

Climate Action And Sdg Synergies: Strengthening The Evidence Base For Synergistic Action, Souran Chatterjee

School of Geography, Earth and Environmental Sciences

No abstract provided.


Exploring Supervisory Experiences After The Legalization Of Recreational Marijuana In Colorado, Charles Daniel Mason Jan 2023

Exploring Supervisory Experiences After The Legalization Of Recreational Marijuana In Colorado, Charles Daniel Mason

Walden Dissertations and Doctoral Studies

AbstractColorado became the first state to decriminalize recreational marijuana in 2014. This new public policy resulted in unproven regulatory changes in any population in the United States. The purpose of the study was to discover the core perspective and experiences of 12 supervisors who experienced this phenomenon in their professional occupations, through the lens of accountability. The risk perceptions of supervisors’ due to policy shifts regarding recreational marijuana in Colorado were analyzed using the Delve system and hand coding. Findings indicated employees’ use of marijuana had a direct impact on productivity, which decreased significantly over time. Employees displayed signs of …


Generational Information Security Awareness And The Role Of Big Five Personality Traits, Gloria Mccue Jan 2023

Generational Information Security Awareness And The Role Of Big Five Personality Traits, Gloria Mccue

Walden Dissertations and Doctoral Studies

AbstractTechnological change drives organizations to safeguard information systems. However, such safeguards are dependent upon people to follow security rules. This study examined generational cohorts and personality traits and their impact on information security awareness. Participants in this study were 137 volunteers who completed an anonymous survey online. Two tools were utilized to collect data from the participants: the Human Aspects of Information Security Questionnaire and the Big Five Inventory, which captured behaviors and personality traits, respectively. The three main generational cohorts represented in the study, Baby Boomers, Generation X, and Generation Y, were in today’s workforce. The results of the …


Nurse Practitioner Education On Caring For Patients Using Medical Marijuana, Zainab Kalokoh Mansaray Jan 2023

Nurse Practitioner Education On Caring For Patients Using Medical Marijuana, Zainab Kalokoh Mansaray

Walden Dissertations and Doctoral Studies

AbstractNurse practitioners are crucial components of community health care because they treat and manage individuals who use medical marijuana. Overuse of medical marijuana without proper examination and certification may result in undesirable patient outcomes, such as increased patient dependency and death, which may have a severe impact on society. The medical marijuana primary care clinic for which this Doctor of Nursing Practice project was developed lacked the information required to certify and evaluate qualifying conditions for medicinal marijuana users. The practice-focused questions investigated how nurse practitioners caring for patients using medical marijuana education based on the National Council of State …


Strategies To Implement Efficient Manufacturing Systems To Improve Companies’ Performance, Ihebuche Miracle Okorie Jan 2023

Strategies To Implement Efficient Manufacturing Systems To Improve Companies’ Performance, Ihebuche Miracle Okorie

Walden Dissertations and Doctoral Studies

Researchers have demonstrated that many manufacturing managers have used successful manufacturing strategies to improve their company’s performance. Manufacturing managers search for successful strategies to implement efficient manufacturing systems because inefficient manufacturing systems can negatively affect their company’s performance. Using transformational leadership as a conceptual framework, the purpose of this qualitative single case study was to explore six U.S. manufacturing managers’ strategies to implement efficient manufacturing systems to improve their company’s performance. The participants were six manufacturing leaders of a company who had successfully employed strategies to implement efficient manufacturing systems. Data were collected from semistructured, open-ended interviews and a review …


Dietary Changes In Preventing Type Ii Diabetes Mellitus Among Young Hispanic Adults, Taiwo Onipede Jan 2023

Dietary Changes In Preventing Type Ii Diabetes Mellitus Among Young Hispanic Adults, Taiwo Onipede

Walden Dissertations and Doctoral Studies

Diabetes mellitus continues to be a major chronic disease affecting the global population today with more prevalence amongst minority groups in the United States. The genetic susceptibility to obesity and higher insulin resistance seen in the Hispanic population puts them at the highest risk for development of Type II Diabetes (T2DM). The alarming increase in young adult T2DM diagnosis led to the project question: How can teaching on dietary changes affect Type II Diabetes diagnosis in predisposed young Hispanic adults? The purpose of this project is to accomplish the goal of Healthy People 2020 towards improving the quality of life …


Adolescent Rejection Sensitivity And Anxiety: The Moderating Effects Of Problem-Solving Skills And Gender, Kathleen Naumann Jan 2023

Adolescent Rejection Sensitivity And Anxiety: The Moderating Effects Of Problem-Solving Skills And Gender, Kathleen Naumann

Walden Dissertations and Doctoral Studies

AbstractRejection sensitivity is the ongoing anxious or angry expectation of interpersonal rejection. Anxiety can potentially have a significant detrimental impact on the mental health of adolescents who are characterized as having rejection sensitivity. Although negative consequences of anxiety on mental health have been studied, there is a limited understanding regarding how rejection sensitive adolescents are at risk for anxiety. This study involved examining relations between adolescent rejection sensitivity and anxiety and whether they were moderated by problem-solving skills, an indicator of resiliency, as well as gender. Theoretical frameworks in this study were the rejection sensitivity model and resilience theory. This …


Community-Based Organization Leaders’ Communication Effectiveness And Effects On Performance Outcomes, Troy N. Nicholas Jan 2023

Community-Based Organization Leaders’ Communication Effectiveness And Effects On Performance Outcomes, Troy N. Nicholas

Walden Dissertations and Doctoral Studies

The purpose of this study was to determine if effective leader communication builds employee relationships that improves organizational performance. Organizational communication is a prominent factor that impacts the outcome of an organization’s goals and assists in executing its mission. There remain some gaps in the current literature considering the work environment and the attitudes of employees as they relate to organizational communication. To address the gap, the constructive grounded theory model was used to construct and analyze a theory of organizational communication. The sample for the study included 12 participants who were leaders or employees in a community-based organizations in …


Teacher Perspectives Regarding Low Teacher Retention In Rural Primary Schools In Tanzania, Tumaini Urio Morgan Jan 2023

Teacher Perspectives Regarding Low Teacher Retention In Rural Primary Schools In Tanzania, Tumaini Urio Morgan

Walden Dissertations and Doctoral Studies

Tanzania, similar to other nations in Sub-Saharan Africa, has been experiencing a severe teacher shortage. The problem that was addressed is that factors influencing rural primary school teachers’ decision to continue teaching in Northeast Tanzania are unknown. The purpose of this qualitative descriptive study was to investigate teachers’ perceptions on teaching in rural primary schools in Northeast Tanzania and the reasons why they remain. This study was guided by self-efficacy theory, a subset of Bandura's social cognitive theory. This descriptive qualitative study explored how rural primary school teachers in northeast Tanzania describe the challenges that cause them to consider abandoning …


Perspectives On Instructional Barriers To Inclusion At Primary Schools In Jamaica, Marcia Hillary Peak Jan 2023

Perspectives On Instructional Barriers To Inclusion At Primary Schools In Jamaica, Marcia Hillary Peak

Walden Dissertations and Doctoral Studies

AbstractInclusive education, which is a global practice in schools, recognizes the rights of all children to equal educational opportunities, including those with special needs or disabilities; however, educators in low-income countries like Jamaica struggle with its implementation. This basic qualitative study explored teachers’ and principals’ perceptions toward instructional and curricular barriers to inclusion in primary level schools. The theory supporting this study is Bronfenbrenner’s development ecology model. Research questions focused on educators’ perspectives of instructional barriers to inclusion. Twelve participants from seven mainstream schools in a single region were interviewed. Data were analyzed using open coding to determine patterns, and …


Strategies To Meet The Budgeted Ratio Between Adjunct And Full-Time Faculty, Tanja Pennino Jan 2023

Strategies To Meet The Budgeted Ratio Between Adjunct And Full-Time Faculty, Tanja Pennino

Walden Dissertations and Doctoral Studies

Human resource managers are concerned that the budgeted ratio between adjunct and full-time faculty will not meet certification standards, but human resource managers lack faculty hiring strategies to manage the budgeted ratio between adjunct and full-time faculty to maintain the institutional operating budget and meet certification standards. Grounded in the human capital theory, the purpose of this qualitative multiple case study was to explore the strategies used by human resource managers to manage the ratio between adjunct faculty and full-time faculty to maintain the institutional operating budget. The participants comprised of four human resource managers within 4-year state colleges in …


Laboratory Practices And Antimicrobial Resistance In A Florida Hospital, Crispina Marie Sy-Trias Jan 2023

Laboratory Practices And Antimicrobial Resistance In A Florida Hospital, Crispina Marie Sy-Trias

Walden Dissertations and Doctoral Studies

Antibiotic resistance is a health threat affecting millions of Americans. Microorganisms develop resistance to antibiotics, rendering them useless for treating infections. The purpose of this quantitative study was to assess the associations between sample processing time and antibiotic resistance and is based on the health belief model. A retrospective specimen tracking activity of data from November 2019 to November 2020 was obtained by random sampling of 246 bacterial cultures. One hundred ninety-six (80%) samples were processed on time, and 50 (20%) were delayed; 167 (68%) samples were determined to have the presence of antimicrobial resistance (AMR), and 79 (32%) with …


Nursing Knowledge And Breastfeeding Education, Mary Aguirre Jan 2023

Nursing Knowledge And Breastfeeding Education, Mary Aguirre

Walden Dissertations and Doctoral Studies

According to the Centers for Disease Control and Prevention, the Healthy People 2020 breastfeeding goal immediately after birth of 81.9% was surpassed in 2016, with approximately 83.8% of babies breastfed shortly after delivery. However, by seven days post birth, this number decreased to 82.9%, reduced even more for infants who were exclusively breastfed to 64.7%. Local research has shown that breastfeeding decreases at one week after discharge, which may be due, in part, to the lack of nurses' knowledge related to breastfeeding. This lack of knowledge related to breastfeeding by the nurses, in turn, may negatively impact the support staff …


Right Treatment Wrong Time: Immunotherapy Administration Post-Radiotherapy Decreases Tumor Burden In A Preclinical Model Of Brain Metastasis, Kathryn Elizabeth Blethen Jan 2023

Right Treatment Wrong Time: Immunotherapy Administration Post-Radiotherapy Decreases Tumor Burden In A Preclinical Model Of Brain Metastasis, Kathryn Elizabeth Blethen

Graduate Theses, Dissertations, and Problem Reports (ETD)

This dissertation (a) provided an in-depth literature review of methods to modulate the blood-brain and blood-tumor barriers to increase drug delivery and efficacy in brain metastases, (b) evaluated the effects of whole-brain radiation therapy on the blood-brain barrier in immunocompetent and immunocompromised mouse models and proposed a mechanism by which the immune response to radiation disrupts the blood-brain barrier, and (c) developed a syngeneic lung cancer brain metastasis model to determine the impact of coordinated immunotherapy administration with radiotherapy. The blood-brain barrier is an impediment to drug delivery to the brain. The inherent leakiness of the blood-tumor barrier does not …


Glial Cell-Specific Contribution Of Pkr-Like Er Kinase (Perk) In Neuroinflammation And Behavior, Anirudhya Lahiri Jan 2023

Glial Cell-Specific Contribution Of Pkr-Like Er Kinase (Perk) In Neuroinflammation And Behavior, Anirudhya Lahiri

Graduate Theses, Dissertations, and Problem Reports (ETD)

Neurological disorders such as multiple sclerosis (MS) are a major public health concern in the US, with no available therapeutic cure. Chronic neuroinflammation and aberrant proteostasis in the central nervous system (CNS) are the major hallmarks of neurological diseases. Endoplasmic Reticulum (ER) is a major cellular organelle involved in protein synthesis, folding and maturation of various secretory and transmembrane proteins. Pathophysiological stressors such as trauma and infection result in misfolded protein accumulation in the endoplasmic reticulum (ER) lumen, which results in ER stress. To regain proteostasis (protein homeostasis), cells activate the unfolded protein response (UPR). UPR is an evolutionarily conserved …


Organizational Continuity Planning For Small Nonprofit Organizations, Lucy Castro Jan 2023

Organizational Continuity Planning For Small Nonprofit Organizations, Lucy Castro

Walden Dissertations and Doctoral Studies

Natural and manufactured disasters may negatively affect a nonprofit organization’s ability to meet its mission. Organizational continuity planning is one tool to help an organization remain practical and mission focused when faced with a natural or manufactured disaster. This qualitative case study explored the essential elements of organizational continuity planning for small nonprofit organizations. Disaster management theory and emergency management theory were used to frame the study. Three research questions guided the study exploring the internal organizational infrastructure challenges organizational leaders face during natural or manufactured disasters; the ways organizational continuity planning assisted nonprofit leaders in providing needed services during …


Strategies Hotel Leaders Use To Improve Employee Engagement, O'Neil Orlando Dacres Jan 2023

Strategies Hotel Leaders Use To Improve Employee Engagement, O'Neil Orlando Dacres

Walden Dissertations and Doctoral Studies

Employee engagement is a significant factor that drives performance and productivity in many organizations. Hotel leaders are typically concerned with the negative impact of disengaged employees, which reduces profitability. Grounded in Herzberg’s two-factor theory, the purpose of this qualitative multiple-case study was to explore strategies hotel leaders use to improve employee engagement. The participants were five hotel leaders in Jamaica who have successfully implemented strategies to improve employee engagement. Data were collected from semistructured interviews and a review of organizational documents. Data were analyzed using thematic analysis, and five themes emerged: staff engagement, communication, rewards and recognition, employee training and …


Carceral Control: A Nationwide Survey Of Criminal Court Supervision Rules, Kate Weisburd Jan 2023

Carceral Control: A Nationwide Survey Of Criminal Court Supervision Rules, Kate Weisburd

Faculty Scholarship

The day-to-day operation of criminal court supervision—including probation, parole, and electronic ankle monitoring—is understudied and undertheorized. To better understand the mechanics of these systems, this study comprehensively analyzes the rules governing people on criminal court supervision in the United States. Drawing on the analysis of 187 public records from all fifty states, this study documents how criminal court supervision functions and impacts daily life. In particular, this study examines the various ways that supervision rules limit or restrict privacy, bodily autonomy, liberty, dignity, speech, and financial independence. This study also explores the nature and prevalence of supervision rules across the …


Scientific Guidelines For Evaluating The Validity Of Forensic Feature-Comparison Methods, David L. Faigman, Nicholas Scurich, Thomas D. Albright Jan 2023

Scientific Guidelines For Evaluating The Validity Of Forensic Feature-Comparison Methods, David L. Faigman, Nicholas Scurich, Thomas D. Albright

Faculty Scholarship

When it comes to questions of fact in a legal context— particularly questions about measurement, association, and causality—courts should employ ordinary standards of applied science. Applied sciences generally develop along a path that proceeds from a basic scientific discovery about some natural process to the formation of a theory of how the process works and what causes it to fail, to the development of an invention intended to assess, repair, or improve the process, to the specification of predictions of the instrument’s actions and, finally, empirical validation to determine that the instrument achieves the intended effect. These elements are salient …


Federal Nonenforcement At A Crossroads, Zachary Price Jan 2023

Federal Nonenforcement At A Crossroads, Zachary Price

Faculty Scholarship

As a novel aspect of “presidential administration”—the president- centered approach to federal governance discussed in a 2001 article by then-Professor and future Supreme Court Justice Elena Kagan—broad federal nonenforcement policies have been a major source of controversy in the past decade. As illustrated by the Obama Administration’s ex- pansive nonenforcement policies relating to marijuana, immigration, and Affordable Care Act implementation, recent presidents have recog- nized nonenforcement’s potential to reshape statutory law to suit an administration’s policy aims. This Article takes stock of this develop- ment as it relates to the past three presidential administrations. While advocating a limited view of …


A Trip To The Border: Legal History And Apa Originalism, Reuel E. Schiller Jan 2023

A Trip To The Border: Legal History And Apa Originalism, Reuel E. Schiller

Faculty Scholarship

This article examines originalist interpretations of the Administrative Procedure Act (APA) from the perspective of a legal historian. After ex­ amining two pieces of originalist scholarship, it concludes that the histor­ ical record may not produce narratives of enough specificity or coherence to assist the originalist project. Nonetheless, it highlights three under-examined subjects of historical inquiry that have the most potential to aid APA originalists: the nature of administrative procedure during the first three decades of the twentieth century when the modem "appellate model" of judicial review emerged; the actual practice of ad­ ministrative law during the New Deal, both …


Administrative Constitutionalism And The History Of The Administrative State, Reuel E. Schiller Jan 2023

Administrative Constitutionalism And The History Of The Administrative State, Reuel E. Schiller

Faculty Scholarship

No abstract provided.


Suing Spacs, Emily Strauss Jan 2023

Suing Spacs, Emily Strauss

Faculty Scholarship

In 2020, the financial world became transfixed by a massive increase in the number of firms going public through special purpose acquisition company (“SPAC”) transactions. A SPAC is a publicly traded company formed solely for the purpose of raising money from investors and choosing a merger partner, thereby bringing the target company public. SPAC shareholders vote on the proposed transaction, but also have the option to redeem their shares for the price paid plus interest prior to the merger. SPACs have always been controversial; they make risky ventures available to unsophisticated investors, may involve acute conflicts of interest, and do …


Rewarding Failure With Patents, Robin Feldman Jan 2023

Rewarding Failure With Patents, Robin Feldman

Faculty Scholarship

It is axiomatic that patents promote success. And yet, a contrary notion—that the patent incentive for medicine should be sufficient to compensate for the losses incurred when other research fails—is quietly permeating modern court decisions, commentary, and Congressional discussions, coloring debates relating to pricing and regulation of medicine. The conceptualization is moving forward unchallenged, as if failure compensation follows logically from the innovation incentives built into the patent construct. As this Article demonstrates, however, the notion is antithetical to patent law, putting modern conceptualizations on a collision course with the history and theory of patents reaching back to this nation’s …


Examining Mental Health Literacy As A Predictor Of Mental Health Service Utilization Among Florida Foster Parents, Adam Johnson Jan 2023

Examining Mental Health Literacy As A Predictor Of Mental Health Service Utilization Among Florida Foster Parents, Adam Johnson

Walden Dissertations and Doctoral Studies

The focus of this study was to examine mental health literacy as a predictor of the mental health service utilization of foster parents after controlling for age. There is an absence of research addressing variables that contribute to the use of mental health services by foster parents. In this nonexperimental study, survey data were collected in an electronic format. Statistical analysis was performed through use of a logistic regression. A mental health literacy conceptual framework was the theoretical foundation of the study. The sample consisted of 42 foster parents from the northwest panhandle of Florida. The study yielded findings indication …


Secondary Teacher Needs To Support Social And Emotional Learning In The Classroom, Ryeneshia Antreanna Hutchinson Jan 2023

Secondary Teacher Needs To Support Social And Emotional Learning In The Classroom, Ryeneshia Antreanna Hutchinson

Walden Dissertations and Doctoral Studies

Survey data from students in Grades 9–12 at L High School (a pseudonym) in an urban district in the southeastern United States suggested that students lack social and emotional learning (SEL) competencies. Efforts to address SEL at the study site have been ineffective. The purpose of this basic qualitative study was to explore secondary teachers’ perceptions of why the efforts to address SEL have been ineffective and to determine what supports teachers believe are needed to address SEL at L High School. The research questions were used to explore teachers’ views on the implementation of SEL, support needed for SEL, …


Challenges In Improving Private Early Childhood Program Quality In Trinidad And Tobago From The Perspectives Of Program Administrators, Elizabeth Josephine King Oliver Jan 2023

Challenges In Improving Private Early Childhood Program Quality In Trinidad And Tobago From The Perspectives Of Program Administrators, Elizabeth Josephine King Oliver

Walden Dissertations and Doctoral Studies

In 2003, the Trinidad and Tobago Ministry of Education recommended that the early childhood care and education sector be regulated to improve the quality of programs. The problem is that the sector remains unregulated, and improving program quality in the private sector remains a challenge. This basic qualitative study examined private early childhood program administrators’ perspectives on challenges to improve program quality in Trinidad and Tobago. The research questions investigated the challenges private early childhood program administrators encountered in improving program quality and support needed for improvement. Ten purposively sampled private early childhood program administrators shared their perspectives. The conceptual …


Strategies For Proper Security Practices In Small Financial Institutions, Adam Leffell Jan 2023

Strategies For Proper Security Practices In Small Financial Institutions, Adam Leffell

Walden Dissertations and Doctoral Studies

Financial institutions remain high targets for threat actors because of potentially lucrativefinancial gains from security breaches. Information technology (IT) security professionals in financial institutions are concerned about weak security strategies that could lead to security breaches. Grounded in the technology acceptance model (TAM), the purpose of this qualitative multiple case study was to explore strategies IT security professionals use to implement proper security practices to prevent security breaches. The participants were three IT security professionals from three different financial institutions that oversee the implementation of security policies and procedures. Data collection involved conducting semi-structured interviews and public documents. Through thematic …


Strategies To Reduce Employee Turnover In The Insurance Industry, Ebony Phillips Jan 2023

Strategies To Reduce Employee Turnover In The Insurance Industry, Ebony Phillips

Walden Dissertations and Doctoral Studies

Employee turnover continues to increase in the insurance industry because no minimum skill or education level is required to enter the U.S. insurance industry. Insurance leaders are concerned with reducing employee turnover, as it creates a risk to employee productivity and profitability. Grounded in Herzberg’s two-factor theory of motivation, the purpose of this qualitative multiple-case study was to explore strategies five insurance leaders from central Kansas used to reduce employee turnover. Data were collected using semistructured virtual interviews and a review of company records. Data were analyzed using Yin’s five-step approach, and three themes emerged: (a) supportive leadership, (b) incentives/benefits, …