Digital Commons Network^™

September 29, 2023 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

A Machine Learning Approach For Dyslexia Detection Using Turkish Audio Records, Tuğberk Taş, Muhammed Abdullah Bülbül, Abas Haşi̇moğlu, Yavuz Meral, Yasi̇n Çalişkan, Gunay Budagova, Mücahi̇d Kutlu

Turkish Journal of Electrical Engineering and Computer Sciences

Dyslexia is a learning disorder, characterized by impairment in the ability to read, spell, and decode letters. It is vital to detect dyslexia in earlier stages to reduce its effects. However, diagnosing dyslexia is a time-consuming and costly process. In this paper, we propose a machine-learning model that predicts whether a Turkish-speaking child has dyslexia using his/her audio records. Therefore, our model can be easily used by smart phones and work as a warning system such that children who are likely to be dyslexic according to our model can seek an examination by experts. In order to train and evaluate, …

Physicochemical Standardisation Of The Homoeopathic Drug, Apis Mellifica: A Preliminary Attempt, Bibaswan Biswas, Satyajit Maity, En Sundaram, Gv Narasimha Kumar, Satish Patel

Indian Journal of Research in Homoeopathy

Background: Unlike the mainstream biomedical system, honeybees’ therapeutic use has long been well documented in the homoeopathic system. The medicine prepared from the whole honeybee, Apis mellifica, is on the Essential Drug List. Objective: An in-depth physicochemical standardisation of this homoeopathic drug is attempted. Material and Methods: In this study, first the raw drug was authenticated, and then its pharmacopoeial parameters were measured, e.g. moisture content, foreign matter, different ash values, alcohol and water-soluble extractive values. Further, the mother tincture of Apis mellifica was prepared from the authentic raw drug. The pharmacopeial parameters of in-house mother tincture …

Homoeopathic Medicines Modulate Inflammatory Functions And Adhesion Receptor Expression In Human Blood Cells: An In Vitro Study, Nibedita Dalpati, Shubham Kumar Rai, Divya Singh, Shiba Prasad Dash, Sukanti S. Sarangi, Mahabahu Nayak, Pranita P. Sarangi

Indian Journal of Research in Homoeopathy

Background: Homoeopathic medicines are used extensively for the treatment of many human diseases and are shown to affect immune cell functions. However, our understanding of the immunomodulatory effects of such medicines and associated mechanisms of action remains limited. Objectives: The present study aims to investigate the immunomodulatory effects of Arsenic album, Rhus toxicodendron, Hepar sulphuris and Bryonia alba on lipopolysaccharide (LPS) induced peripheral blood neutrophils and monocytes. Materials and Methods: In this work, neutrophils and monocytes were treated with different homoeopathic dilutions of 30C potency separately, followed by stimulation with the LPS, to examine the immunomodulatory effects of these …

Research Highlights, Arti Goyal, Anamika Singh

Indian Journal of Research in Homoeopathy

Research Highlights

September 29, 2023 Minutes, Swosu Faculty Senate

Faculty Senate Minutes

No abstract provided.

Effect Of Sex And Cross-Sex Hormone Treatment On Renal Monocarboxylate-Transporter Expression In Rats, Hao Wei, Annie Lee, Qing Zhang, Melanie A. Felmlee

Pacific Faculty Work

Proton- and sodium-dependent monocarboxylate transporters (MCTs/SMCTs) are determinants of renal clearance through the renal reabsorption of monocarboxylate substrates. Prior studies with intact females and males, ovariectomized females and castrated males have revealed the hormonal regulation of renal monocarboxylate-transporter expression, prompting investigation into the regulatory role of individual hormones. The aim of the present study is to evaluate the effect of exogenous sex and cross-sex hormones on renal MCT1, MCT4, CD147 and SMCT1 mRNA and membrane-bound protein expression. Ovariectomized (OVX) females and castrated (CST) male Sprague Dawley rats received estrogen and/or progesterone, testosterone, or a corresponding placebo treatment for 21 days …

Stepwise Dynamic Nearest Neighbor (Sdnn): A New Algorithm For Classification, Deni̇z Karabaş, Derya Bi̇rant, Peli̇n Yildirim Taşer

Turkish Journal of Electrical Engineering and Computer Sciences

Although the standard k-nearest neighbor (KNN) algorithm has been used widely for classification in many different fields, it suffers from various limitations that abate its classification ability, such as being influenced by the distribution of instances, ignoring distances between the test instance and its neighbors during classification, and building a single/weak learner. This paper proposes a novel algorithm, called stepwise dynamic nearest neighbor (SDNN), which can effectively handle these problems. Instead of using a fixed parameter k like KNN, it uses a dynamic neighborhood strategy according to the data distribution and implements a new voting mechanism, called stepwise voting. Experimental …

An Improved Binary Quadratic Interpolation Optimization For 0-1 Knapsack Problems, Sara Salem

Sustainable Machine Intelligence Journal

This paper presents a new binary optimization technique for solving the 0–1 knapsack problem. This algorithm is based on converting the continuous search space of the recently proposed quadratic interpolation optimization (QIO) into discrete search space using various V-shaped and S-shaped transfer functions; this algorithm is abbreviated as BQIO. To further improve its performance, it is effectively integrated with a uniform crossover operator and a swap operator to explore the discrete binary search space more effectively. This improved variant is called BIQIO. Both BQIO and BIQIO are assessed using 20 well-known knapsack instances and compared to four recently published metaheuristic …

An Improved Light Spectrum Optimizer For Parameter Identification Of Triple-Diode Pv Model, Safaa Saber, Sara Salem

Sustainable Machine Intelligence Journal

Over the last few decades, researchers have paid attention to finding an effective and efficient metaheuristic algorithm that can determine the ideal parameters for PV models. In this study, to determine the TDM’s nine unknown parameters, we will examine the efficacy of a recently proposed metaheuristic algorithm called light spectrum optimizer (LSO). To further enhance the effectiveness of LSO in estimating those unknown parameters, a new improved variant called ILSO is developed. This variant employs LSO in conjunction with two newly developed update systems to improve its exploration and exploitation operators. We compare the best fitness value, worst fitness value, …

Volume Cxliii, Number 2, September 29, 2023, Lawrence University

The Lawrentian

No abstract provided.

Luna, Cami Henyan

Stimulus: A Medical Humanities Journal

A piece on my expericne with with pet therapy

Creator Biographies, The Stimulus Team

Stimulus: A Medical Humanities Journal

No abstract provided.

Tmem135 Links Peroxisomes To The Regulation Of Brown Fat Mitochondrial Fission And Energy Homeostasis, Donghua Hu, Min Tan, Dongliang Lu, Brian Kleiboeker, Xuejing Liu, Hongsuk Park, Alexxai V Kravitz, Kooresh I Shoghi, Yu-Hua Tseng, Babak Razani, Akihiro Ikeda, Irfan J Lodhi

2020-Current year OA Pubs

Mitochondrial morphology, which is controlled by mitochondrial fission and fusion, is an important regulator of the thermogenic capacity of brown adipocytes. Adipose-specific peroxisome deficiency impairs thermogenesis by inhibiting cold-induced mitochondrial fission due to decreased mitochondrial membrane content of the peroxisome-derived lipids called plasmalogens. Here, we identify TMEM135 as a critical mediator of the peroxisomal regulation of mitochondrial fission and thermogenesis. Adipose-specific TMEM135 knockout in mice blocks mitochondrial fission, impairs thermogenesis, and increases diet-induced obesity and insulin resistance. Conversely, TMEM135 overexpression promotes mitochondrial division, counteracts obesity and insulin resistance, and rescues thermogenesis in peroxisome-deficient mice. Mechanistically, thermogenic stimuli promote association between …

Sglt2 Inhibitors Among Patients With Heart Failure With Preserved Ejection Fraction: A Meta-Analysis Of Randomised Controlled Trials, Akash Jaiswal, Vikash Jaiswal, Song Peng Ang, Muhammad Hanif, Ananya Vadhera, Vibhor Agrawal, Tushar Kumar, Anagha M. Nair, Vamsikalayan Borra, Vamsi Garimella

School of Medicine Publications

Background: Sodium-glucose co-transporter 2 (SGLT2) inhibitors have been recommended in the practice guidelines for the treatment of patients with heart failure with reduced ejection fraction; however, their effects among patients with preserved ejection fraction have been debatable.

Objective: We aim to evaluate the SGLT2 inhibitor effect among patients with heart failure with reduced ejection fraction, including DELIVER and EMPEROR-Preserved trials.

Methods: We performed a systematic literature search using the PubMed, Embase, Scopus, and Cochrane libraries for relevant articles from inception until August 30th, 2022. Statistical analysis was performed by calculating hazard ratio (HR) using the random effect model with a …

Elastic Stable Intramedullary Nail Fixation Versus Submuscular Plate Fixation Of Pediatric Femur Shaft Fractures In School Age Patients: A Prisma-Compliant Systematic Review And Meta-Analysis, Donglai Hu, Zihang Xu, Tao Shi, Hui Zhong, Yuting Xie

Faculty, Staff and Student Publications

BACKGROUND: Studies of clinical outcomes that compare the elastic stable intramedullary nail (ESIN) with the submuscular plate (SMP) were controversial. The meta-analysis was performed to summarize existing evidence, aiming to determine whether ESIN was superior to SMP in pediatric femur shaft fractures.

METHODS: Search strategies followed the recommendations of the Cochrane collaboration. Electronic searches such as PubMed, Embase, Web of Science, Cochrane were systematically searched for publications concerning ESIN and SMP from the inception date to March 2023. Two investigators independently searched, screened, and reviewed the full text of the article. Disagreements generated throughout the process were resolved by consensus, …

New Jak3-Insl3 Fusion Transcript-An Oncogenic Event In Cutaneous T-Cell Lymphoma, Loka Reddy Velatooru, Cheng Hui Hu, Pedram Bijani, Xiaohong Wang, Pierr Bojaxhi, Madeleine Duvic

Faculty, Staff and Student Publications

Constitutively activated tyrosine kinase JAK3 is implicated in the pathogenesis of cutaneous T-cell lymphomas (CTCL). The mechanisms of constitutive JAK3 activation are unknown although a JAK3 mutation was reported in a small portion of CTCL patients. In this study, we assessed the oncogenic roles of a newly identified JAK3-INSL3 fusion transcript in CTCL. Total RNA from malignant T-cells in 33 patients with Sézary syndrome (SS), a leukemic form of CTCL, was examined for the new JAK3-INSL3 fusion transcript by RT-PCR followed by Sanger sequencing. The expression levels were assessed by qPCR and correlated with patient survivals. Knockdown and/or knockout assays …

Evaluation Of The Effectiveness Of Foot-And-Mouth Disease Vaccination Of Animals In The Buffer Zone Of The Republic Of Armenia In 2016–2020, Pertsh Tumanyan, Gayane Chobanyan, Jenna E Achenbach

Faculty, Staff and Student Publications

BACKGROUND: Foot-and-mouth disease (FMD) is a high impact viral disease of livestock for which vaccines are extensively used for limiting the spread of infection. Armenia shares a border with both Turkey and Iran where FMD is endemic, making vaccination an important component of Armenia's control strategy. Additionally, Armenian veterinary services utilize both passive and active monitoring for prevention control.

METHODS: We sought to determine the immune status of animals vaccinated against FMD and to evaluate the effectiveness of our vaccination policy in Armenia. This was conducted in three regions including Shirak, Armavir, and Ararat Region which are located in the …

Learning To Care For Dangaba, Anne Poelina, Yin Paradies, Sandra Wooltorton, Edwin L. Mulligan, Laurie Guimond, Libby Jackson-Barrett, Mindy Blaise

Research outputs 2022 to 2026

In a Kimberley place-based cultural story, Dangaba is a woman whose Country holds poison gas. Her story shows the importance of cultural ways of understanding and caring for Country, especially hazardous places. The authors contrast this with a corporate story of fossil fuel, illustrating the divergent discourses and approaches to place. Indigenous and local peoples and their knowledge, cultures, laws, philosophies and practices are vitally important to Indigenous lifeways and livelihoods, and critically significant to the long-term health and well-being of people and place in our locality, region and world. We call for storying and narratives from the pluriverse of …

The No-Self Thesis: Counterarguments From Abnormal Psychology, Elma Berisha

UBT International Conference

The no-self thesis is said to originate in David Hume’s (1739) “bundle theory of self,” questioning the human self as a mere bundle of fleeting perceptions without ontological reality. In contemporary discourse, the self is sandwiched between top-down and bottom-up reductionisms: those with biological and cognitive arguments that reduce the self to a lower, ontological level, on the one hand, and those who hold cultural-linguistic constructionist positions, on the other hand, reducing the self to a higher level. In both cases, self reductionism is a prelude to complete self elimination. On these conceptions, what we call “self” may be nothing …

A Neurodevelopmental Perspective To Improve Innovation In Preventive Treatment Of Substance Use Disorders, Ismael Perez, John Vandeberg, Mario Gil

Research Symposium

Background: Midbrain dopaminergic neurons have been associated with substance use disorders (Blaess & Ang, 2015). Understanding their neurodevelopment during early stages of life is fundamental for innovating preventive care treatments. The animal model Monodelphis domestica has been proposed as an excellent candidate to study neurodevelopmental changes due to the ease of access to see changes in their embryonic development (Mate et al., 1994). The purpose of our study is to inform how brain cells, including and especially dopaminergic neurons, mature by quantifying their number during early development. Additionally, the study aims to compare different midbrain areas and track neurodevelopmental changes …

Beta-3 Adrenergic Receptor Blockade Prevents Alterations In Feeding Behavior In Lymphoma-Bearing Mice In A Sex-Dependent Manner, Isaias Gutierrez-Leal, Diana Caballero-Hernández, Alonso Orozco-Flores, Moises Franco-Molina, Ricardo Gomez-Flores, Patricia Tamez-Guerra, Cristina Rodríguez-Padilla

Research Symposium

Introduction: Cancer cachexia is a metabolic syndrome defined by an ongoing loss of adipose and muscular tissue and is characterized by a reduced food intake. Local b-3 adrenergic receptor activation in adipose tissue induces lipolysis, whereas b-3 signaling in tumors has been shown to be tumorigenic in some cancer models. Therefore, b-3 signaling may be a therapeutic target in cancer cachexia. The aim of this study was to assess the role of b-3 adrenergic signaling in feeding behavior, body composition, and tumor progression in the L5178Y-R murine lymphoma model.

Methods: In our study we used BALB/c mice of both sexes, …

Watermelon Seed Extract Inhibits Protein Aggregation And Formation Of Advanced Glycation End-Products, Faiyaz Ahmed, Satish A

International Journal of Health and Allied Sciences

BACKGROUND: Glycation of proteins is a key element in the onset of diabetes consequences. The potential of medicinal plants to inhibit the progression of glycation complications provides a significant opportunity as an alternative therapy. METHODS: The effect of watermelon seed extract (WMSE) on antioxidant capacity was assessed based on radical scavenging activity and metal chelation activity. Further the inhibition of Advanced glycation end-products (AGEs) formation was assessed by using different sources of amine (haemoglobin, bovine serum albumin, G.K peptide) and sugar sources (δ-gluconolactone, methylglyoxal, ribose). Aminoguanidine (AG) used as standard drug. RESULTS: Due to the presence of various phytochemicals that …

Geospatial Artificial Intelligence (Geoai): Applications In Health Care, K S Sahana, C B Karthik, Mounika M Sree, M Chaithra, Stavelin K Abhinandithe, B Snehalatha, R Sridhar, S Balasubramanian, B Madhu

International Journal of Health and Allied Sciences

GeoAI is a new emerging research area that refers to set of technologies that integrate AI technology with a diversity of GIS (Geographic Information System) techniques. The present study observed that GeoAI goes beyond current GIS expectations and into the domain of possibility in the not-too-distant future. This emerging interdisciplinary science will lead us to sustainable decisions and explore the most suitable solutions to the existing problems. GeoAI has the potential to transform current geography and geomatics programs by incorporating a GeoAI dimension into modern GIS curricula. In this review, we have studied the application GeoAI in various healthcare fields. …

Plant Derived Bioactive Compounds, Their Anti-Cancer Effects As An Alternative Target Treatment Strategy For Breast Cancer: An Updated Overview, Pruthvish Reddy, Sushma Pradeep, S.M. Gopinath, Shiva Prasad Kollur, Chandan Shivamallu

International Journal of Health and Allied Sciences

For decades, cancer has been a major public health concern worldwide owing to its high mortality rate. Many therapeutic strategies have come up in the scientific world, but it's pitiful to know that synthetic chemotherapeutic agents either cause adverse effects or cancer cells develop resistance to these agents. Plant-derived chemotherapeutic agents present a wide range of therapeutics and most are yet to be discovered. In the current review, we have discussed the tumoricidal properties of Mucuna pruriens (seed), Withania coagulans (berry), Anacyclus pyrethrum (rhizome), Arachis hypogea (leaf), Rhizaoma polygoni (root) and Terminalia chebula (fruit). We have also tried to summarize …

Molecularly Imprinted Electrochemical Sensor Based On Poly (O-Phenylenediamine) For Sensitive Detection Of Oxycodone In Water, Pranaya Charkravarthula, Amos Mugweru

College of Science & Mathematics Departmental Research

This work was aimed at the development of a sensitive electrochemical detection method for oxycodone in water. Molecularly imprinted electrodes were formed by electro-polymerization process using o-phenylenediamine as a monomer. The electro-polymerization was performed on glassy carbon electrodes in the presence of oxycodone before the extraction of entrapped oxycodone molecules. Various electrochemical techniques were employed to monitor the polymerization and response of the fabricated electrodes toward oxycodone. These techniques included cyclic voltammetry (CV), square wave voltammetry (SWV), differential pulse voltammetry (DPV) and electrochemical impedance spectroscopy (EIS). The oxycodone concentration was determined using SWV by measuring the change in the oxidation …

The Indiana Statesman, September 28, 2023, Indiana State University

Student Newspaper

President Curtis delivers address; US soldier expelled from North Korea; Doctor charged with sexual assault; Neighbor dispute prompts SWAT standoff near SW Atlanta school

Genomic And Transcriptomic Analyses Reveal Polygenic Architecture For Ecologically Important Traits In Aspen (Populus Tremuloides Michx.), Jennifer F. L. Riehl, Christopher T. Cole, Clay J. Marrow, Hilary L. Barker, Carolina Bernhardsson, Kennedy Rubert-Nason, Pär K. Ingvarsson, Richard L. Lindroth

Aspen Bibliography

Intraspecific genetic variations in foundation species such as aspen (Populus tremuloides Michx.) shapes their impact on forest structure and function. Identifying genes underlying ecologically important traits is key to understanding that impact. Previous studies, using single-locus genome-wide association (GWA) analyses to identify candidate genes, have identified fewer genes than anticipated for highly heritable quantitative traits. Mounting evidence suggests that polygenic control of quantitative traits is largely responsible for this "missing heritability" phenomenon. Our research characterized the genetic architecture of 30 ecologically important traits using a common garden of aspect through genomic and transcriptomic analyses. A multilocus association model revealed …

Europe’S Animal Welfare Reforms Are Under Threat, Lewis Bollard

General – Farm Animal Issues

The article discusses the European Union’s stalled efforts to implement comprehensive farm animal welfare reforms, highlighting political, economic, and lobbying challenges.

Faculty Senate Committee Agenda October 2, 2023, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• 3:00 Call to Order. Maureen Hearns
• 3:05 University Business. Elizabeth Cantwell, President | Larry Smith, Provost
• 3:20 Faculty Senate Business. Maureen Hearns | John Ferguson | Grant Cardon
• 3:25 Information
• 3:40 Reports
• 3:50 Old Business
• 4:05 New Business
• Adjourn: