Digital Commons Network^™

Ethnomedicinal Importance Of Family Lamiaceae And Family Rosaceae Among Local Communities Of Dir Kohistan, Khyber Pakhtunkhwa, Pakistan, Midrar Ullah, Atta Ullah, Akhtar Aman, Hamid Hussain Afridi, Muhammad Afzal Naeem

Journal of Bioresource Management

The present study was conducted to document the medicinal uses of Family Lamiaceae and Rosaceae in Dir Kohistan during the summer of 2016. Field visits were arranged to different resource-based areas of Dir Kohistan and plants were identified according to their phytogeographic locations. The study revealed that nine species of the family Lamiaceae and seven species of the family Rosaceae are used by the local community for the treatment of human ailments. They utilized these plants through personal experiences and ancestral prescriptions. The plants were used for different health disorders like kidney pain, lung infections, jaundice, as carminative, antimicrobial, antifungal, …

Effects Of Bacillus Thuringiensis, Beauveria Bassiana, Neem, And A Tomato Inter-Crop On Diamondback Moth (Plutella Xylostella L.) (Lepidoptera: Plutellidae) In Tharaka-Nithi County, Kenya, Ceciliah N. Ngugi, Jesca N. Mbaka Mbaka, Hellen W. Muthengi

Tanzania Journal of Science

Cabbage (Brassica oleracea var. capitata) is an important crop in Kenya, ranked 3rd among the exotic vegetables. Diamondback moth (DBM) is a major cabbage pest that can cause a 100% loss in yield if not well managed. Farmers indiscriminately use synthetic pesticides associated with environmental, health, and pest resistance concerns to manage the DBM. To increase the availability of technologies for effective management of DBM in Kenya, three biopesticides; BioPower (Beauveria bassiana 1.0 x 108 CFUs/g), Dipel DF® (Bacillus thuringiensis subsp. kurstaki), Neemraj Super 3000 (Azadirachtin 0.3% EC), and a tomato inter-crop were evaluated. Cabbages (30 plants) spaced at 40 …

Hydro-Geochemistry And Related Processes Controlling The Composition Of Thermal Waters In The Lake Natron Basin, Northern Tanzania, Edista A. Abdallah, Charles H. Kasanzu, Crispin P. Kinabo, Akira Imai

Tanzania Journal of Science

Lake Natron Basin (LNB) forms part of the eastern branch of the East African Rift System (EARS) in Tanzania. The basin is endowed with thermal springs flowing towards the lake from the western, northwestern, southwestern and eastern parts. The western, northwestern and south-western thermal springs emanate from fractures in the basaltic rocks while in the east, they originate from the western flank of the Gelai volcano. There are limited studies on these springs, thus their geochemical differences and distributions of physicochemical parameters are not well understood. A hydrogeochemical study was conducted to interpret available geochemical data from the LNB springs, …

Microplastics In Marine Sediments From Dar Es Salaam Coast: Spatial Distribution And Characterization, Macarius P. Mtega, Matobola J. Mihale, Kessy F. Kilulya

Tanzania Journal of Science

The purpose of the research was to determine the spatial distribution and characterization of microplastics in marine sediments of beaches along the Indian Ocean of Dar es Salaam coast. The sediment samples were extracted in triplicate using floatation method followed by digestion of organic debris, then analyzed using At-FTIR spectrophotometer and stereomicroscope. The mean concentrations of microplastics for Kijichi Beach were 700 ± 907 particles/m2 at 1 cm, 859 ± 839 particles/m2 at 5 cm and 590 ± 782 particles/m2 at 10 cm; from Palm Beach were 157 ± 15 particles/m2 at 1 cm, 130 ± 182 particles/m2 at 5 …

Enhancing Service Restoration In Tanzanian Power Grid Using Internet Of Things Sensors And Renewable Energy Sources, Rukia J. Mwifunyi, Daudi C. Mnyanghwalo, Shamte J. Kawambwa

Tanzania Journal of Science

The increased dependence on the electric power grid, coupled with the increasing number of new customers, motivates the need to improve the reliability and resilience of the electric distribution systems. Modern distribution systems are becoming more resilient against power outages due to the increasing integration of Distributed Energy Resources (DERs) and the availability of efficient mechanisms for load shedding. Several studies considered fault detection and Service Restoration (SR) as separate problems without considering the implementation feasibility of integrating both solutions. To ensure the resiliency in the power system, it is important to have proper mechanisms which integrate sensing, detection, and …

Public Perceptions Of Water Quality In The Lake Bunyonyi Sub-Catchment, Western Uganda, Alex Saturday, Thomas J. Lyimo, Siajali Pamba, Susan Kangume, Jeniffer Turyatemba

Tanzania Journal of Science

Lake Bunyonyi ecosystem plays vital roles in water resource conservancy and tourism. Nevertheless, the rapid increase in human population and the unrelenting human activities are threatening the values, functions, and ecological integrity of the lake. In this study, the public perceptions of drinking water quality and its health implications in the Lake Bunyonyi Sub-catchment, Western Uganda are presented. A closed-ended questionnaire was administered to 267 respondents living within one Kilometre away from the lake shores. Besides, observation and interview methods were used to complement data collected by the questionnaire method. Results indicate that the prominent activities around the lake are …

Existing Evidence For Influenza B Virus Adaptations To Drive Replication In Humans As The Primary Host, Matthew J. Pekarek, Eric A. Weaver

Nebraska Center for Virology: Faculty Publications

Influenza B virus (IBV) is one of the two major types of influenza viruses that circulate each year. Unlike influenza A viruses, IBV does not harbor pandemic potential due to its lack of historical circulation in non-human hosts. Many studies and reviews have highlighted important factors for host determination of influenza A viruses. However, much less is known about the factors driving IBV replication in humans. We hypothesize that similar factors influence the host restriction of IBV. Here, we compile and review the current understanding of host factors crucial for the various stages of the IBV viral replication cycle. While …

Purification And Characterization Of Mitochondrial Mg2+-Independent Sphingomyelinase From Rat Brain, Seok Kyun Kim, Jong Hoon Won, Jae Hong Lee, Ji Min Jang, In Chul Shin, Zhicheng Fu, Sung Yun Jung, Eui Man Jeong, Dae Kyong Kim

Faculty, Staff and Students Publications

Sphingomyelinase (SMase) catalyzes ceramide production from sphingomyelin. Ceramides are critical in cellular responses such as apoptosis. They enhance mitochondrial outer membrane permeabilization (MOMP) through self-assembly in the mitochondrial outer membrane to form channels that release cytochrome c from intermembrane space (IMS) into the cytosol, triggering caspase-9 activation. However, the SMase involved in MOMP is yet to be identified. Here, we identified a mitochondrial Mg

Trimeric Complex Interactions Of Antp-Tbp With Tfiieb And Exd Are Involved In The Genetic Control Of Drosophila Melanogaster, Gustavo Jiménez Mejía, Ruben De Jesus Montalvo Mendez, Claudia Dalila Altamirano Torres, Diana Reséndez Pérez

Research Symposium

Background: Homeoproteins are transcriptional factors (TFs) that shape animal body axes during development. These TFs are highly conserved and represent one of the most fascinating groups of regulatory molecules. Reports shown the multiplicity of interactions in hox proteins, as complexes trimeric involved to transcriptional activity. The study of trimeric complexes in Hox interactome will allow the better understanding of Hox genetic regulation during embryonic development.

Methodology: Using a new combination BiFCFRET approach performed in HEK293, the quantification was performed by FRETTY of ImageJ. Fly crosses were incubated at 25ºC on standard yeast-agar-cornmeal medium. Embryo cuticle preparations were carried out according …

The Impact Of Biological Sex On Motor Function And Responses To Novel Environments In The Gray Short-Tailed Opossum (Monodelphis Domestica), Esperanza I. Alaniz, Ismael Perez, Sasawan Heingraj, Katelynn Renteria, Cristian M. Botello, Joseph C. Cantu, John L. Vandeberg, Mario Gil

Research Symposium

Background: Understanding the different stress reactions in different environments can help us understand stress factors. Studying animal behavior is important for translational research for mental health improvement.

Previous literature has shown that stress is a risk factor for higher cancer incidence and poorer cancer survival. (Klejbor & Turlejski., 2012), as well as mental health outcomes. Understanding of how stress is related to cancer can help improve therapeutic outcomes as preventive measures (Glaser et al., 1987).

Methods: Using the Rota Rod apparatus, 12 animals (3 males, 9 females) were tested at 36 rpm for a maximum of 400 seconds (Madroñal et …

Investigating Monodelphis Domestica As An Alternative To The Mus Musculus As An Animal Model, Cristian M. Botello, John L. Vandeberg, Mario Gil

Research Symposium

Background: Mus Musculus is one of the first and one of the most widely used animal models in current neuroscience literature (Phifer-Riley & Nachmann, 2015). However, the research community needs alternatives to rodent models to study the mammalian brain. Research is needed to see if antibodies that target tyrosine hydroxylase, which are well researched in mice, can also be used to study the Monodelphis domestica brain.

Methods: Following transcardial perfusions and brain extractions, mouse and opossum brains were processed and stained for tyrosine hydroxylase (and with Nissl). Opossum brains will then be sliced and processed using IHC methods to compare …

Whole Genome Sequence Data Implicate Rbfox1 In Epilepsy Risk In Baboons, Mark Z. Kos, Melanie A. Carless, Lucy Blondell, Mary M. Leland, Koyle D. Knape, Harald H. H. Goring, Charles A. Szabo

Research Symposium

Background: Baboons exhibit a genetic generalized epilepsy (GGE) that resembles juvenile myoclonic epilepsy and may represent a suitable genetic model for human epilepsy. The genetic underpinnings of epilepsy were investigated in a baboon colony at the Southwest National Primate Research Center (San Antonio, TX) through the analysis of whole-genome sequence (WGS) data.

Methods: Baboon WGS data were obtained for 38 cases and 19 healthy controls from the NCBI Sequence Read Archive and, after standard QC filtering, two subsets of variants were examined: (1) 20,881 SNPs from baboon homologs of 19 candidate GGE genes; and (2) 36,169 protein-altering SNPs. Association tests …

Characterization Of Epithelial Growth Factor Transcripts Identified In Crotalus Atrox Venom, Ivan Lopez, Ying Jia

Research Symposium

Epithelial Growth Factor (EGF) is the primary source in regeneration and stimulation of essential fibroblasts cells commonly found in epithelium. Studies have shown that snake venom components are becoming a growing factor in treating illnesses such as cancer, muscular dystrophy, chronic pain, blood pressure, blood clotting, etc. EGF in human cells contains a promising quaternary structure that can bind to snake venom metalloproteinases, proposing a means of activating biochemical responses through protein-protein interactions to regulate unwanted cellular functions. This supports promising research in achieving a greater understanding of regulation along cellular pathways through ligands, increasing the likelihood of targeting unwanted …

Knowing The Unknowable: Visions Of Troubled Lands, Estella C. Kuchta

Journal of Contemplative and Holistic Education

This paper describes the author’s clairvoyant visions of war and personal experiences of transrational knowledges. It is an account of one Westerner coming to know outside of and despite Western episteme. Transrational knowing was modelled by companion dogs in the author’s childhood and literary figures in early adulthood, and was experienced as a means of self-protection. Western culture fosters skepticism about transrational knowledges, such as psychic visions and telepathic connections. This paper asserts that transrational knowing—whether between humans, other species, or humans and other species—is a valid and readily available form of knowing that exists outside of and in spite …

Free, Prior Informed Consent And Extractive Industry: Indigenous Action Is The Past, Present, And Future Of Global Environmental Justice, Paige Bellamy

Environmental and Earth Law Journal (EELJ)

Free, Prior Informed Consent ("FPIC") from the UN Declaration on the Rights of Indigenous Peoples has been central to global Indigenous action against extractive industries’ harmful practices. Yet, it is often not fully recognized as a sovereign right, which hinders Indigenous peoples’ ability to use it to its full potential. Historically, FPIC has been deemed a consultation right, not a right to “veto” industry action on Indigenous land. Countries that have interpreted FPIC as a mere consultation right have allowed further exploitation of Indigenous peoples, usually leading to environmental and humanitarian disasters. However, when courts have respected the right to …

Soaps And Shampoos: Proposals To Reform Regulation In The United States Personal Care Market To Decrease Deforestation From Palm Oil Imports, Kelsey Weston

Environmental and Earth Law Journal (EELJ)

Palm oil is the world's most highly sought-after vegetable oil due to its multifaceted uses and cheap cost of production. However, producing this versatile oil comes at a high cost to one of the largest biodiversity on the planet. Over the last two centuries, Indonesia and Malaysia have become the main producers and exporters of palm oil but they are also home to the largest number of mammal species in the world that have seen a staggering decline in populations. Furthermore, palm oil production has caused excessive release of greenhouse gases, increased disruption of forestland, and economic poverty for smallholders …

Nuclear Powered International Commercial Shipping: A Note On The Greenest Solution And The Challenges Of International Regulation, Rebecca Mcreynolds

Environmental and Earth Law Journal (EELJ)

To meet the environmental demands imposed by the International Maritime Organization, the commercial shipping industry’s use of predominantly marine diesel fuel will need to change drastically. Current answers to these environmental concerns include the use of biofuels, battery packs, and liquified natural gas, but these are short-term solutions that will not fully meet environmental demands in the long run. Nuclear propulsion, however, is a tried-and-true resolution. The use of nuclear energy results in virtually no environmental impact and has successfully been used by the US Navy for the past 75 years. Unfortunately, the commercial use of nuclear propulsion is stalled …

Reversing Quiet Destruction: Florida's Attempt To Regulate Pfas Known As Forever Chemicals, A. Colleen Donald

Environmental and Earth Law Journal (EELJ)

Introduced by manufacturing companies in the 1940s, Per-and polyfluorinated substances (“PFAS”) which consist of a group of over 6,000 chemicals, have insidiously made their way into the bloodstream of humans and into the environment. These nearly indestructible, “forever chemicals” that were once thought to be safe for use in firefighting foams, cosmetics, food packaging, non-stick cookware, and water-resistant clothing, are now found to be toxic. PFAS have been found in animals, aquatic life, and natural resources, and are associated with illnesses in humans: PFAS have been linked to various cancers, reproductive issues in women, and birth defects in children. As …

A 3d Printed Microneedle System For Transdermal Drug Delivery Of Anticancer Drugs, Md Jasim Uddin, Tanvir Ahmed, Dennis Douroumis

Research Symposium

Background: Transdermal delivery of drugs is an attractive alternative to the conventional route of administration as oral delivery. The hypodermic injections are painful and less patient compliance. Microneedles (MNs) are micron-sized, minimally invasive needles to deliver a wide range of molecules (e.g., small, DNA, vaccines etc.) to the upper portion of the dermis in a sustained and controlled manner, without causing any pain. The introduction of 3D printing technologies in the fabrication of MN will promote one-step manufacturing tools and scale-up for the delivery devices of anticancer drugs.

Methods: The 3D printed MN (3DMN) arrays were fabricated using Stereolithography (SLA), …

Systems Network Analysis Of Protein Interaction Network (Pin) For Deducing Molecular Mechanistic Action Of Bap Induced Carcinogenesis, Anukriti ., Anupam Dhasmana, Uma Bhardwaj

Research Symposium

Background: Benzo[a]pyrene (BaP), a polycyclic aromatic hydrocarbon, has been placed in group 1 by IARC which indicates that it is a potential carcinogen to human beings. It has shown tumorigenic properties in approximately all animal model systems. In the current study, we have tried to identify the most probable biomolecular targets of BaP using systems biology approach.

Method: All the proteins that interact with BaP were extracted from T3DB. STRING-db was used to generate the Protein- protein interaction network (PPIN). Various apps of cytoscape software were used for network analysis, modulation and GO enrichment analysis. By developing biokinetic …

From Bench To Bedside: Bridging The Gap Between Animal Behavior Research And The Study Of Human Personality And Psychopathology, William Reckley, Mario Gil

Research Symposium

Background: Most psychopathology focuses on the current mental picture of an individual with some including relations to the past experience. One problem with the biomedical studies of psychopathologies is the difficulty in using animals to describe and model these mental states in humans. This difficult task has been confounded by the inability to classify animals in a way that will provide general models that will allow better translation to hypotheses in humans. Therefore, the present investigation explores statistical/research strategies to organize variables using lab animals to facilitate the translation of this information to humans.

Methods: Factor analysis/PCA was used to …

2023 15th Annual Student Center For Science Engagement Research Symposium, Student Center For Science Engagement

Student Center for Science Engagement Research Symposium

Student presentations in Biology, Chemistry, Physics, Earth Science, Environmental Science, Computer Science, Mathematics, & Psychology

The Student Movement Volume 108 Issue 3: Todos Unidos: Andrews Celebrates Hispanic Heritage Month, Grace No, Nehemiah Sitler, Savannah Tyler, Nathaniel Miller, Katrina Johnson, Nailea Soto, Amelia Stefanescu, Reagan Mccain, Melissa Moore, Andrew Francis, Robert Zhang, Charisse Lapuebla, Katherine Pierre, Caitlin Adap, Rodney Bell Ii, Wambui Karanja

The Student Movement v. 108 (2023-2024)

HUMANS

Hispanic Heritage Month, Grace No

Bigger and Better! Hailey and AUSA Coming With New Events for This Year!, Nehemiah Sitler

Say Hello to Professor Harris, Grace No

Welcome to the Writing Center, Savannah Tyler

ARTS & ENTERTAINMENT

An Evening with Ada Limón, Nathaniel Miller

AU Architecture Program Part I, Katrina Johnson (senior, architecture)

Makarios: Hispanic Expression through Ministry, Nailea Soto

Stitch by Stitch We Cross-Stitch, Amelia Stefanescu

This Semester at HPAC: The Power of Live Music, Reagan McCain

NEWS

AULA Goes Back-to-School, Melissa Moore

International Students Share Thoughts on International Basketball, Andrew Francis

Science Complex Hosts Panel on Faith …

"The Rat Trap" By Pandora Pound, Andrew Rowan

Tales of WellBeing

The book critically analyzes animal research and argues for greater emphasis on human cell technologies and clinical research.

Laboratory Animals And Non-Animal Alternatives, Andrew Rowan

Tales of WellBeing

The use of animals in laboratories is declining worldwide as new non-animal methods become more sophisticated and relevant.

Elephant Care And Welfare In Southeast Asia Today: Part 3, Bjarne Clausen, Taweepoke Angkawanish

Tales of WellBeing

Elephant care traditions in Southeast Asia are changing as elephant welfare becomes a growing issue.

Effects Of Cortisol, Epinephrine, And Bisphenol Contaminants On The Transcriptional Landscape Of Marine Mammal Blubber, Lauren Kashiwabara, Laura Pirard, Cathy Debier, Daniel Crocker, Jane Khudyakov

Pacific Faculty Work

Top ocean predators such as marine mammals are threatened by intensifying anthropogenic activity, and understanding the combined effects of multiple stressors on their physiology is critical for conservation efforts. We investigated potential interactions between stress hormones and bisphenol contaminants in a model marine mammal, the northern elephant seal (NES). We exposed precision-cut adipose tissue slices (PCATS) from blubber of weaned NES pups to cortisol (CORT), epinephrine (EPI), bisphenol A (BPA), bisphenol S (BPS), or their combinations (CORT-EPI, BPA-EPI, and BPS-EPI) ex vivo and identified hundreds of genes that were differentially regulated in response to these treatments. CORT altered expression of …

Full Issue, The Stimulus Team

Stimulus: A Medical Humanities Journal

No abstract provided.

Opioid Impacts On Cardiovascular Health, Erjola Toska, Harvey N. Mayrovitz

HPD Articles

The prevalence of opioid use in the current opioid epidemic era has led to a public health emergency due to the ties to mortality and morbidity. Studies have investigated opioids’ impacts on different aspects of cardiovascular health, although there seems to be a lack of a current concise review. Therefore, the aim of this literature review is to provide a summary of the most recent studies from the past decade that postulate a connection between opioids and their impact on cardiovascular health while highlighting conflicting areas among published research. For this literature review, three databases, PubMed (NLM), EMBASE, and Web …

Adaptive Octree Meshes For Simulation Of Extracellular Electrophysiology, Christopher Bc Girard, Dong Song

Engineering Faculty Articles and Research

Objective. The interaction between neural tissues and artificial electrodes is crucial for understanding and advancing neuroscientific research and therapeutic applications. However, accurately modeling this space around the neurons rapidly increases the computational complexity of neural simulations. Approach. This study demonstrates a dynamically adaptive simulation method that greatly accelerates computation by adjusting spatial resolution of the simulation as needed. Use of an octree structure for the mesh, in combination with the admittance method for discretizing conductivity, provides both accurate approximation and ease of modification on-the-fly. Main results. In tests of both local field potential estimation and multi-electrode stimulation, dynamically adapted meshes …