Digital Commons Network^™

Heart Disease Prediction Under Machine Learning And Association Rules Under Neutrosophic Environment, Ahmed A. El-Douh, Songfeng Lu, Ahmed Abdelhafeez, Ahmed M. Ali, Alber S. Aziz

Neutrosophic Systems with Applications

Early identification and precise prediction of heart disease have important implications for preventative measures and better patient outcomes since cardiovascular disease is a leading cause of death globally. By analyzing massive amounts of data and seeing patterns that might aid in risk stratification and individualized treatment planning, machine learning algorithms have emerged as valuable tools for heart disease prediction. Predictive modeling is considered for many forms of heart illness, such as coronary artery disease, myocardial infarction, heart failure, arrhythmias, and valvar heart disease. Resource allocation, preventative care planning, workflow optimization, patient involvement, quality improvement, risk-based contracting, and research progress are …

Creating Land With Artificial Oyster Rings: Legal Challenges From State Owned Bottom Land To Living Shorelines, Faith Parker, Will Reach

Virginia Coastal Policy Center

The Virginia Sea Grant program approached VCPC to conduct research in partnership with the William & Mary Public Policy Program and a James Madison University (JMU) architecture professor, Jori Erdman. Professor Erdman is researching the viability of creating land with artificial oyster rings based on similar projects seen in Louisiana. Professor Erdman has provided the diagrams of the project used throughout this paper. Ultimately, this paper examines some legal issues raised by the use of these rings to prevent coastal erosion or act as a flooding buffer for commercial or residential buildings. With this goal in mind, this paper addresses …

Christine Helmer And Shannon Craigo-Snell, Eds., Claiming God: Essays In Honor Of Marilyn Mccord Adams, Claire Brown Peterson

Faith and Philosophy: Journal of the Society of Christian Philosophers

No abstract provided.

Growing South Dakota (Fall 2023), College Of Agriculture, Food And Environmental Sciences

Growing South Dakota (Publication of the College of Agriculture, Food and Environmental Sciences)

[Page] 3 Back-to-Back Champions: SDSU Quarter Scale Tractor Team Repeats International Win
[Page] 6 CAFES Welcomes New Members to College Leadership Team
[Page] 9 Vikram Mistry Retires After Nearly 40-Year Career at SDSU
[Page] 12 Bill Gibbons Retires After 36 Years at SDSU
[Page] 13 Nic Uilk: Klingbeil Endowed Educator in Precision Agriculture
[Page] 15 SDSU Students Study Abroad
[Page] 19 CAFES Faculty Claim National Awards
[Page] 21 Dairy Alum Sanne de Bruijn Grabs Global Opportunities
[Page] 23 SDSU Extension Cohort Programs
[Page] 25 Summer Field Day Highlights
[Page] 29 Jackrabbits Now and Then

Deep Learning For Studying Materials Stability And Solving Thermodynamically Consistent Pdes With Dynamic Boundary Conditions In Arbitrary Domains, Chunyan Li

Theses and Dissertations

Deep learning has achieved remarkable success in various fields, including image processing, natural language processing, and signal processing, ushering in a transformative era in research and real-life applications. This rise underscores the transformative capabilities of deep learning, with its innovative approach to function approximation. Traditionally, approximation theory relied on additive constructions, but deep neural networks have introduced a compositional approach, reshaping the landscape of function approximation. This thesis explores the efficacy of this compositional construction within the realm of material science and the solution of thermodynamically consistent partial differential equations with thermodynamically consistent dynamic boundary conditions in arbitrary domains. As …

Oscars Vs. Ozone: The Motion Picture Industry’S Impact On Climate Change And What They Are Doing About It, Alexis J. Simpson

Senior Theses

This thesis focuses on demonstrating that the motion picture industry, which includes film and television production (and thus will also be called ‘the film and television industry’), has notably contributed to the global effects of climate change. Such contributions can stem from the industry’s emissions and waste, with examples including travel for cast and crew, energy use for production equipment (some of which run on diesel), and disposable physical sets and costumes. The intention here is to give an accurate picture of current production practices and share examples of progress in the industry that are combating the negative impacts of …

Beneath The Surface: An Investigation Into The Relation Between Power, Dehumanization, And Objectification In And Initial Social Interaction, Lillian Hefner

Honors Program: Senior Projects (Public)

Objectification theory suggests that women are disproportionately affected by objectification leading them to experience more negative health outcomes such as depression and eating disorders. Further research on objectification and synthesis of leading theories in the area suggest that power may be one factor likely to predict the objectification and dehumanization of women. One important dimension of this objectification and dehumanization is the environment in which it occurs. Few studies examine a social/dating context as the current study does. We expected the men in the study who felt a stronger sense of power during the interaction would exhibit more objectification of …

A Prescription For Deceit: Pharmaceutical Frauds’ Dangerous Side Effects, Calvin Mcmurtrey

The Synapse: Intercollegiate science magazine

No abstract provided.

Scouring For Meaning, And Hope, In The Rubble Of Gaza, Karim Haggag, Firas Al-Atraqchi

Faculty Journal Articles

The latest war in Gaza has shocked the world by its sheer violence, and the potential to escalate into a full-blown regional conflict. Worst of all has been the international community’s deafening silence.

Reciprocity And Beyond: Explaining Meat Transfers In Savanna-Dwelling Chimpanzees At Fongoli, Senegal, Angela M. Achorn, Stacy Lindshield, Papa Ibnou Ndiaye, Jeffrey Winking, Jill D. Pruetz

Anthropology Faculty Publications

Objectives

To understand the function of food sharing among our early hominin ancestors, we can turn to our nonhuman primate relatives for insight. Here, we examined the function of meat sharing by Fongoli chimpanzees, a community of western chimpanzees (Pan troglodytes verus) in southeastern Sénégal.

Materials and Methods

We tested three non-mutually exclusive hypotheses that have been used to explain patterns of food sharing: kin selection, generalized reciprocity, and meat-for-mating opportunities. We analyzed meat sharing events (n = 484) resulting from hunts, along with data on copulations, age-sex class, and kinship to determine which variables predict the …

Unruly Ideas: A History Of Kitawala In Congo, Nicole Eggers

Ohio University Press Open Access Books

Original oral and ethnographic sources inform this conceptual history of power in central Africa, imagined through the lens of Kitawala religious practices.

Unruly Ideas: A History of Kitawala in Congo recounts the multifaceted history of the Congolese religious movement Kitawala from its colonial beginnings in the 1920s through its continued practice in some of the most conflict-riven parts of the eastern Democratic Republic of Congo today. Drawing on a rich body of original oral, ethnographic, and archival research, Nicole Eggers uses Kitawala as a lens through which to address the complex relationship between politics, religion, healing, and violence in central …

Richmond Law Magazine: Autumn 2023

Richmond Law Magazine

The technology battlefield

Beacons for equal justice

An inspiring, intentional new space

Podcasting As A Pedagogy: Teacher Perceptions Of Podcast Use And Creation In The Classroom, Rebecca J. Hobby

Selected Honors Theses

Podcasting is an innovative technology medium that has impacted the world with its new ideas, perspectives, and connections between listeners and hosts. While this medium has grown exponentially in many spheres, it is relatively new in educational settings. This thesis seeks to determine whether educators are ready to implement podcast listening and producing in their classrooms. It also seeks to ascertain educators’ perceptions of the benefits and challenges of podcasting. A survey was conducted asking teachers and college students preparing to become teachers about their observations and understandings of podcast use in classrooms. The findings indicated that access to professional …

Signs & Symbols, Fall 2023, Illinois State University, Department Of Sociology And Anthropology

Signs & Symbols

Newsletter of the Illinois State University Department of Sociology and Anthropology. An email newsletter version of this document is available at https://web.archive.org/web/20260223213535/https://news.illinoisstate.edu/newsletters/signs-symbols-fall-23/.

Revisiting “Sites Of Spiritan Spirituality, May 14-June 3, 2023” (Supplemental Content), Dora Janeway Odarenko

Spiritan Horizons

No abstract provided.

The Spiritan Mission & Communication: Guided By The Spirit To Respond And Adapt To The World, Lazarus Langbiir Cssp

Spiritan Horizons

No abstract provided.

Education In The Spiritan Mission In Congo-Brazzaville: A Historical-Critical Overview, Alphée Mpassi Cssp

Spiritan Horizons

No abstract provided.

Review Of Toxocariasis At A Children's Hospital Prompting Need For Public Health Interventions, Karina M Robinson, Megan N Carey, Sarah J Smith, Brendan Sullivan, Alisa R Nelson, Sarah M Gunter, Jill E Weatherhead

Faculty, Staff and Students Publications

BACKGROUND: Toxocariasis, caused the by dog and cat roundworm, is one of the most common zoonotic helminth infections in the United States and can lead to severe lifelong morbidity in children. Although historical seroprevalence studies have identified a high frequency of toxocariasis regionally in the United States, there are few studies linking epidemiology and clinical disease in children. The study objective was to examine the contemporary epidemiology of pediatric toxocariasis within an endemic US region.

METHODS: We conducted an epidemiologic study analyzing children diagnosed with toxocariasis presenting to a tertiary pediatric hospital in Texas from 2010 to 2021. We examined …

Molecular Insights Using Spatial Transcriptomics Of The Distal Lung In Congenital Diaphragmatic Hernia, Manuel Eliezer Cantu Gutierrez, Nahir Cortes-Santiago, J D Hammond, Jamie Gilley, Joselyn Rojas Quintero, Hui Li, Francesca Polverino, Jason P Gleghorn, Sundeep G Keswani

Faculty, Staff and Students Publications

Abnormal pulmonary vascular development and function in congenital diaphragmatic hernia (CDH) is a significant factor leading to pulmonary hypertension. The lung is a very heterogenous organ and has marked cellular diversity that is differentially responsive to injury and therapeutic agents. Spatial transcriptomics provides the unmatched capability of discerning the differences in the transcriptional signature of these distinct cell subpopulations in the lung with regional specificity. We hypothesized that the distal lung parenchyma (selected as a region of interest) would show a distinct transcriptomic profile in the CDH lung compared with control (normal lung). We subjected lung sections obtained from male …

Obesity Paradox Or Hypoxia Preconditioning: How Obstructive Sleep Apnea Modifies The Obesity-Mi Relationship, Ahmed Bahammam, Javad Razjouyan

Faculty, Staff and Students Publications

OBJECTIVES: The objective of this study was to evaluate the interaction between obesity and obstructive sleep apnea on acute MI in hospital mortality.

METHODS: This retrospective cohort study utilized Veterans Health Administration data from years 1999-2020. Participants were categorized according to their body mass index (BMI) to non-obese (BMI

RESULTS: Among 72,036 veterans with acute-MI hospitalization, individuals with obesity and obstructive sleep apnea (OB-SA) had the lowest in-hospital mortality rate (1.0%) compared to those without obesity and obstructive sleep apnea (nOB-nSA, 2.8%), with obesity but without obstructive sleep apnea (OB-nSA, 2.4%), and with obesity and obstructive sleep apnea (nOB-SA, 1.4%). …

Human Intestinal Organoids As Models To Study Enteric Bacteria And Viruses

Faculty, Staff and Students Publications

Laboratory studies of host-microbe interactions have historically been carried out using transformed cell lines and animal models. Although much has been learned from these models, recent advances in the development of multicellular, physiologically active, human intestinal organoid (HIO) cultures are allowing unprecedented discoveries of host-microbe interactions. Here, we review recent literature using HIOs as models to investigate the pathogenesis of clinically important enteric bacteria and viruses and study commensal intestinal microbes. We also discuss limitations of current HIO culture systems and how technical advances and innovative engineering approaches are providing new directions to improve the model. The studies discussed here …

Neurodevelopmental Deficits And Cell-Type-Specific Transcriptomic Perturbations In A Mouse Model Of Hnrnpu Haploinsufficiency, Andrew K Ressler, Elizabeth E Rafikian, Sabrina Petri, Verity A Letts, Jiajie Teoh, Junqiang Ye, Sophie Colombo, Yueqing Peng, Mu Yang, Michael J Boland, Wayne N Frankel, David B Goldstein

Faculty, Staff and Students Publications

Heterozygous de novo loss-of-function mutations in the gene expression regulator HNRNPU cause an early-onset developmental and epileptic encephalopathy. To gain insight into pathological mechanisms and lay the potential groundwork for developing targeted therapies, we characterized the neurophysiologic and cell-type-specific transcriptomic consequences of a mouse model of HNRNPU haploinsufficiency. Heterozygous mutants demonstrated global developmental delay, impaired ultrasonic vocalizations, cognitive dysfunction and increased seizure susceptibility, thus modeling aspects of the human disease. Single-cell RNA-sequencing of hippocampal and neocortical cells revealed widespread, yet modest, dysregulation of gene expression across mutant neuronal subtypes. We observed an increased burden of differentially-expressed genes in mutant excitatory …

Mammalian Aging Driven By Transcription Going Awry

Faculty, Staff and Students Publications

The mechanisms that underlie increased cryptic transcription during senescence and aging have been poorly understood. Sen et al. recently identified cryptic transcription start sites (cTSSs) and chromatin state changes that may contribute to cTSS activation in mammals. Their results indicate that enhancer-promoter conversion may drive cryptic transcription in senescence.

Bronchopulmonary Dysplasia – Associated Pulmonary Hypertension: An Updated Review, Natalie Villafranco, Bheru Gandhi, Milenka Cuevas Guaman, Binoy Shivanna

Faculty, Staff and Students Publications

Bronchopulmonary dysplasia (BPD) is the leading cause of chronic lung disease in infants and the commonest complication of prematurity. Advances in respiratory and overall neonatal care have increased the survival of extremely low gestational age newborns, leading to the continued high incidence of BPD. Pulmonary hypertension (PH) represents the severe form of the pulmonary vascular disease associated with BPD, and affects almost one-third of infants with moderate to severe BPD. PH responds suboptimally to pulmonary vasodilators and increases morbidity and mortality in BPD infants. An up-to-date knowledge of the pathogenesis, pathophysiology, diagnosis, treatment, and outcomes of BPD-PH can be helpful …

A Novel Pathogenic Mutation Of Mecp2 Impairs Chromatin Association Independent Of Protein Levels, Harini P Tirumala, Carlo Vetralla, Sameer S Bajikar, Yan Li, Hu Chen, Qi Wang, Zhenyu Wu, Bing Tang, Mahla Zahabiyon, Aleksandar Bajic, Xiangling Meng, Jack J Ferrie, Anel Lagrone, Ping Zhang, Jean J Kim, Jianrong Tang, Zhandong Liu, Xavier Darzacq, Nathaniel Heintz, Robert Tjian, Huda Y Zoghbi

Faculty, Staff and Students Publications

Loss-of-function mutations in MECP2 cause Rett syndrome (RTT), a severe neurological disorder that mainly affects girls. Mutations in MECP2 do occur in males occasionally and typically cause severe encephalopathy and premature lethality. Recently, we identified a missense mutation (c.353G>A, p.Gly118Glu [G118E]), which has never been seen before in MECP2, in a young boy who suffered from progressive motor dysfunction and developmental delay. To determine whether this variant caused the clinical symptoms and study its functional consequences, we established two disease models, including human neurons from patient-derived iPSCs and a knock-in mouse line. G118E mutation partially reduces MeCP2 abundance …

Time To Establish An International Vaccine Candidate Pool For Potential Highly Infectious Respiratory Disease: A Community’S View, Esayas Kebede Gudina, Asma Khalil, Rahaman Ahmed, Ayorinde Babatunde James, Anna Roca, Mosoka Papa Fallah, Andrew Macnab, William C Cho, John Eikelboom, Farah Naz Qamar, Peter Kremsner, Miquel Oliu-Barton, Ivan Sisa, Birkneh Tilahun Tadesse, Florian Marks, Lishi Wang, Jerome H Kim, Xia Meng, Yongjun Wang, Alyce D Fly, Cong-Yi Wang, Sara W Day, Scott C Howard, J Carolyn Graff, Marcello Maida, Kunal Ray, Carlos Franco-Paredes, Tapfumanei Mashe, Ngashi Ngongo, Jean Kaseya, Nicaise Ndembi, Yu Hu, Maria Elena Bottazzi, Peter J Hotez, Ken J Ishii, Gang Wang, Dianjun Sun, Lotfi Aleya, Weikuan Gu

Faculty, Staff and Students Publications

In counteracting highly infectious and disruptive respiratory diseases such as COVID-19, vaccination remains the primary and safest way to prevent disease, reduce the severity of illness, and save lives. Unfortunately, vaccination is often not the first intervention deployed for a new pandemic, as it takes time to develop and test vaccines, and confirmation of safety requires a period of observation after vaccination to detect potential late-onset vaccine-associated adverse events. In the meantime, nonpharmacologic public health interventions such as mask-wearing and social distancing can provide some degree of protection. As climate change, with its environmental impacts on pathogen evolution and international …

Convergent Escape Behaviour From Distinct Visual Processing Of Impending Collision In Fish And Grasshoppers, Alexander F Mendoza, Bidisha Halder, Thomas Preuss, Fabrizio Gabbiani

Faculty, Staff and Students Publications

In animal species ranging from invertebrate to mammals, visually guided escape behaviours have been studied using looming stimuli, the two-dimensional expanding projection on a screen of an object approaching on a collision course at constant speed. The peak firing rate or membrane potential of neurons responding to looming stimuli often tracks a fixed threshold angular size of the approaching stimulus that contributes to the triggering of escape behaviours. To study whether this result holds more generally, we designed stimuli that simulate acceleration or deceleration over the course of object approach on a collision course. Under these conditions, we found that …

The 2017 American College Of Cardiology/American Heart Association Hypertension Guideline And Blood Pressure In Older Adults, Kathryn Foti, Stephen P Juraschek, John W Mcevoy, Vijay Nambi, Mercedes R Carnethon, Erin D Michos, Sadiya S Khan

Faculty, Staff and Students Publications

Introduction: The 2017 American College of Cardiology/American Heart Association blood pressure guideline redefined hypertension and lowered the blood pressure treatment target. Empirical data on the guideline's impact are needed.

Methods: Data were analyzed from Atherosclerosis Risk in Communities study participants who attended baseline pre-guideline (2016-2017) and post-guideline (2018-2019) visits with baseline systolic blood pressure between 120 and 159 mmHg. Participants were grouped according to baseline systolic blood pressure by change in classification under the new guideline as follows: not reclassified (120-129 mmHg), reclassified to Stage 1 hypertension (130-139 mmHg), and reclassified to Stage 2 hypertension (140-159 mmHg). Means and 95% …

A Pilot Genome-Wide Association Study Meta-Analysis Of Gastroparesis, Emily Mitchell, Anita Pandit, Suraj Pullapantula, Cheryl Bernard, Maris Teder-Laving, Francine Z Marques, Tonu Esko, Braden Kuo, Robert J Shulman, Bruno P Chumpitazi, Kenneth L Koch, Irene Sarosiek, Thomas L Abell, Richard W Mccallum, Henry P Parkman, Pankaj J Pasricha, Frank A Hamilton, James Tonascia, Matthew Zawistowski, Gianrico Farrugia, Madhusudan Grover, Mauro D'Amato

Faculty, Staff and Students Publications

BACKGROUND: Gastroparesis (GP) is characterized by delayed gastric emptying in the absence of mechanical obstruction.

OBJECTIVE: Genetic predisposition may play a role; however, investigation at the genome-wide level has not been performed.

METHODS: We carried out a genome-wide association study (GWAS) meta-analysis on (i) 478 GP patients from the National Institute of Diabetes and Digestive and Kidney Diseases Gastroparesis Clinical Research Consortium (GpCRC) compared to 9931 population-based controls from the University of Michigan Health and Retirement Study; and (ii) 402 GP cases compared to 48,340 non-gastroparesis controls from the Michigan Genomics Initiative. Associations for 5,811,784 high-quality SNPs were tested on …

Predictors And Moderators Of Treatment Outcomes For Anxious Children Randomized To Computer-Assisted Cognitive Behavioral Therapy Or Standard Community Care, Alison Salloum, Eric A Storch

Faculty, Staff and Students Publications

Introduction:

Computer-assisted cognitive behavioral therapy (CCBT) for childhood anxiety disorders may aid the dissemination of CBT, while maintaining treatment fidelity. Although CCBT is an effective intervention, not everyone benefits equally from treatment. Identifying patient characteristics that predict who will benefit from treatment and to what extent can help with matching patients to suitable interventions, and allow researchers and clinicians to modify, and individualize, their treatment formats more effectively. Such predictors and moderators have not yet been examined for CCBT outcomes in anxious children and studies of more traditional treatment formats have yielded inconsistent results.

Methods:

Using data from a randomized …