Digital Commons Network^™

Temperature And Predators As Interactive Drivers Of Community Properties, John Delong, Kyle E. Coblentz, Stella F. Uiterwaal, Chika Akwani, Miranda E. Salsbery

School of Biological Sciences: Faculty Publications

The effects of warming on ecological communities emerge from a range of potentially asymmetric impacts on individual physiology and development. Understanding these responses, however, is limited by our ability to connect mechanisms or emergent patterns across the many processes that drive variation in demography. Further complicating this understanding is the gain or loss of predators to many communities, which may interact with changes in temperature to drive community change. Here we conducted a factorial warming and predation experiment to test generalized predictions about responses to warming. We used microcosms with a range of protists, rotifers, and a gastrotrich, with and …

Use And Effectiveness Of Wildlife Exits Designed For Ocelots And Other Mesocarnivores On A South Texas Highway, Zarina N. Sheikh, Jamie E. Langbein, Kevin W. Ryer, Md Saydur Rahman, Christopher A. Gabler, John H. Young Jr., Richard Kline

School of Earth, Environmental, & Marine Sciences Faculty Publications

Movement is a key component of survival and reproduction, often causing wildlife to cross heavily trafficked highways, resulting in road mortalities by oncoming vehicles. Fencing and crossing structures are commonly regarded as effective mitigation structures to reduce these mortalities. In south Texas, ten wildlife exits (WE) were installed along State Highway 100 in conjunction with existing mitigation structures to provide the US endangered ocelot (Leopardus pardalis), a medium-sized spotted wild cat, a safe option to escape the right of way (ROW). The objectives of this study were to determine the effectiveness and species usage and to estimate the …

Interval-Valued Fermatean Neutrosophic Shortest Path Problem Via Score Function, Said Broumi, S. Krishna Prabha, Vakkas Uluçay

Neutrosophic Systems with Applications

Contemporary mathematical techniques have been crafted to address the uncertainty of numerous real-world settings, including Fermatean neutrosophic fuzzy set theory. Fermatean neutrosophic fuzzy set is an extension of combining Fermatean and neutrosophic sets. A Fermatean neutrosophic set was developed to enable the analytical management of ambiguous data from relatively typical real-world decision-making scenarios. Decision-makers find it challenging to determine the degree of membership (MG) and non-membership (NG) with sharp values due to the insufficient data provided. Intervals MG and NG are suitable options in these circumstances. In this article, the shortest route issue is formulated using an interval set of …

A Retrospective, Observational Study Of 12 Cases Of Expanded-Access Customized Phage Therapy: Production, Characteristics, And Clinical Outcomes, Sabrina I Green, Justin R Clark, Haroldo H Santos, Kyle E Weesner, Keiko C Salazar, Saima Aslam, J William Campbell, Sarah B Doernberg, Emily Blodget, Michele I Morris, Gina A Suh, Karam Obeid, Fernanda P Silveira, Andrey A Filippov, Katrine L Whiteson, Barbara W Trautner, Austen L Terwilliger, Anthony Maresso

Faculty, Staff and Students Publications

BACKGROUND: Antimicrobial resistance (AMR) is undermining modern medicine, a problem compounded by bacterial adaptation to antibiotic pressures. Phages are viruses that infect bacteria. Their diversity and evolvability offer the prospect of their use as a therapeutic solution. Reported are outcomes of customized phage therapy for patients with difficult-to-treat antimicrobial resistant infections.

METHODS: We retrospectively assessed 12 cases of customized phage therapy from a phage production center. Phages were screened, purified, sequenced, characterized, and Food and Drug Administration-approved via the IND (investigational new drug) compassionate-care route. Outcomes were assessed as favorable or unfavorable by microbiologic and clinical standards. Infections were device-related …

The George-Anne Inkwell Edition, Georgia Southern University

The Inkwell

No abstract provided.

Ppp1r12c Promotes Atrial Hypocontractility In Atrial Fibrillation, Srikanth Perike, Francisco J Gonzalez-Gonzalez, Issam Abu-Taha, Frederick W Damen, Laurin M Hanft, Ken S Lizama, Anahita Aboonabi, Andrielle E Capote, Yuriana Aguilar-Sanchez, Benjamin Levin, Zhenbo Han, Arvind Sridhar, Jacob Grand, Jody Martin, Joseph G Akar, Chad M Warren, R John Solaro, Sang-Ging Ong, Dawood Darbar, Kerry S Mcdonald, Craig J Goergen, Beata M Wolska, Dobromir Dobrev, Xander H T Wehrens, Mark D Mccauley

Faculty, Staff and Students Publications

Background: Atrial fibrillation (AF)-the most common sustained cardiac arrhythmia-increases thromboembolic stroke risk 5-fold. Although atrial hypocontractility contributes to stroke risk in AF, the molecular mechanisms reducing myofilament contractile function remain unknown. We tested the hypothesis that increased expression of PPP1R12C (protein phosphatase 1 regulatory subunit 12C)-the PP1 (protein phosphatase 1) regulatory subunit targeting MLC2a (atrial myosin light chain 2)-causes hypophosphorylation of MLC2a and results in atrial hypocontractility.

Methods: Right atrial appendage tissues were isolated from human patients with AF versus sinus rhythm controls. Western blots, coimmunoprecipitation, and phosphorylation studies were performed to examine how the PP1c (PP1 catalytic subunit)-PPP1R12C interaction …

The Diamond, October 13, 2023, Dordt University

Dordt Diamond

• Front Page: Defender Crazies Re-Ignites Dordt Athletics; Somdi Baccam: The Man Behind the Camera; Marine Band Shares Gift of Music with Dordt Community
• News: Dordt Adds Off Campus Study Program in Baltimore; What Happens if the Government Shuts Down?; Caleb Meulenberg Brings Industry Experience to the Ag Teach [sic] Program
• Feature: International Friendship Family Program Shares Culture; Senior Recital Highlights Violin and Organ; Dordt Chapel: Hearing God's Voice; What Do Professors Do Over Heartland?
• Arts & Entertainment: Kylie Sorensen Takes the Stage in Senior Voice Recital; Beautiful Things: Dordt Worship Releases New Singles; D'Arte Club Hosts …

Taoisigh And The Arts (Kevin Rafter: Martello, 2022)., Connell Vaughan

Research Outputs: 2025-Present

Kevin Rafter’s short book is an entertaining taste of the use and abuse of the arts in Ireland by successive Taoisigh(the plural form of the title of the Irish elected head of state, ‘Taoiseach’). It covers a century of cultural policy juxtaposed with artistic responses of the times, to reveal a story of official neglect and the privileging of economic concerns. Until the establishment of the Department of Arts in 1993 only one Taoiseach truly embraced his responsibilities to the arts and Charles J. Haughey would do so in a way that emphasised grand gestures to support his image all …

The Faithful Vassal: The Suzerain-Vassal Covenant Relationship As A Biblical-Theological Theme Connecting The Old And New Testament Narratives, Tyler Matthew Brown

Doctoral Dissertations and Projects

Much has been written within the scholarly literature regarding the nature of the Mosaic Law as being one which reflects a suzerain-vassal covenant between Yahweh and the nation of Israel in the Old Testament, and particularly in the book of Deuteronomy. Likewise, it has been well established by scholars that this covenant relationship serves as a key biblical-theological theme within the narrative of the former prophets, the so-called “Deuteronomistic history.” At the same time, however, there have been relatively few attempts to examine the ways in which this critical theme features throughout the remainder of the biblical narratives, from the …

Synthesis And Antitumor Activity Of Brominated-Ormeloxifene (Br-Orm) Against Cervical Cancer, Mohammed Sikander, Shabnam Malik, John Apraku, Sonam Kumari, Parvez Khan, Hassan Mandil, Sheema Khan, Murali M. Yallapu, Meena Jaggi, Subhash C. Chuahan

School of Medicine Publications

Aberrant regulation of β-catenin signaling is strongly linked with cancer proliferation, invasion, migration, and metastasis, thus, small molecules that can inhibit this pathway might have great clinical significance. Our molecular modeling studies suggest that ormeloxifene (ORM), a triphenylethylene molecule that docks with β-catenin, and its brominated analogue (Br-ORM) bind more effectively with relatively less energy (−7.6 kcal/mol) to the active site of β-catenin as compared to parent ORM. Herein, we report the synthesis and characterization of a Br-ORM by NMR and FTIR, as well as its anticancer activity in cervical cancer models. Br-ORM treatment effectively inhibited tumorigenic features (cell proliferation …

Introduction To Scholarly Communication, Nicole Webber

Bear GRADS

Academic professionals are sharing their research, scholarship, and creative works in more formats and to wider audiences than ever before. As this system of communication evolves, the opportunities for scholars expand, and so do their responsibilities as both consumers and producers of information. Maximizing the influence of our work means understanding and managing how it is affected by various methods of dissemination, evaluation, access, and preservation. This session will introduce the system of scholarly communication and highlight the issues most pertinent to graduate students and early career researchers.

My Summer Girl, Jai Ahluwalia

Quill & Scope

No abstract provided.

The Difficult Search For Life After Death, Corinne Stonebraker

Quill & Scope

No abstract provided.

Requiem: Heart-Wrenching “Mass Song” Or A Smoke Screen?, Marie Peteuil

Quest

Bibliographic Trace

Research in progress for ENGL 2333: World Literature II

Faculty Mentor: W. Scott Cheney, Ph.D.

In an 1870 letter, Emily Dickinson described poetry this way: “If I read a book and it makes my whole body so cold no fire can ever warm me, I know that is poetry. If I feel physically as if the top of my head were taken off, I know that is poetry. These are the only way I know it. Is there any other way?” During the twentieth century, the Russian poet Anna Akhmatova wrote poetry that embodies Dickinson’s intense definition. My …

Spartan Daily, October 12, 2023, San Jose State University, School Of Journalism And Mass Communications

Spartan Daily, 2023

Volume 161, Issue 23

Vulnerability Of Elevation-Restricted Endemic Birds Of The Cordillera De Talamanca (Costa Rica And Panama) To Climate Change, Zhen Lui, Luis Sandoval, Lauren B. Sherman, Andrew M. Wilson

Environmental Studies Faculty Publications

Animals endemic to tropical mountains are known to be especially vulnerable to climate change. The Cordillera de Talamanca (Costa Rica and Panama) is a geographically isolated mountain chain and global biodiversity hotspot, home to more than 50 endemic bird species. We used eBird community science observations to predict the distributions of a suite of 48 of these endemic birds in 2006–2015, and in 2070, under four climate change scenarios. Species distributions were predicted using program Maxent, incorporating elevation, satellite derived habitat data, and WorldClim climate variables. Model fit, as assessed by Area under the Receiver Operator Curve (AUC), was very …

Archaeology And Hauntology: An Ongoing, Stalled Conversation, Colby Dickinson

Theology: Faculty Publications and Other Works

It is certainly possible that we might learn to better acknowledge the spirits of our ancestors who came before us, as well as to recognize them in such ways that we also learn to embrace the ‘woven density’ of our own lives, our histories and our communities. By doing so, we might begin to discover that the spirits we had thought were removed from our modern, secularized world never fully left us, just as the irrationality of our humanity cannot be fully tamed via a reductive, rational and scientific outlook on life. There are, as Bruno Latour had frequently argued, …

Learning And Gender In Everyday Life, Jocey Quinn

Plymouth Institute of Education

This paper focuses on the learning that happens in everyday life, beyond the formal learning environments of schools, colleges, and universities or even beyond community and adult education. It draws on posthuman concepts of ‘learning affect’ and ‘new worlds’ to conceptualise this as ‘invisible education’, affective and transformative, unrecognised but powerful and formative. Such invisible education has a powerful impact on formations of gender, class, race, sexuality, and disability and is thus a key field of enquiry with important consequences for gender equality. The paper will draw on a diverse range of grant funded qualitative, research projects to focus on …

Vista: October 12, 2023, University Of San Diego

USD Vista (1965-)

No abstract provided.

Fibroblast Growth Factor 21 Has A Diverse Role In Energetic And Reproductive Physiological Functions Of Female Beef Cattle, Ligia D. Prezotto, Jessica A. Keane, Andrea S. Cupp, Jennifer F. Thorson

Department of Animal Science: Faculty Publications

Fibroblast growth factor 21 (FGF21) has been identified in multiple mammalian species as a molecular marker of energy metabolism while also providing negative feedback to the gonads. However, the role of FGF21 in regulating the energetic and reproductive physiology of beef heifers and cows has yet to be characterized. Herein, we investigated the temporal concentrations of FGF21 in female beef cattle from the prepubertal period to early lactation. Circulating concentrations of FGF21, non-esterified fatty acids, plasma urea nitrogen, glucose, and progesterone were assessed. Ultrasonography was employed to determine the onset of puberty and resumption of postpartum ovarian cyclicity as well …

Burrowing Owl Skull, Nicolas M. Caracuel, Hannah Lesko, David Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

October 12, 2023, Csusb

Coyote Chronicle (1984-)

No abstract provided.

Ryan Hyslope, Trombone, With Sean Botkin, Piano, October 12, 2023 [Program], University Of Northern Iowa. School Of Music.

Music Recital Programs

Program of a music recitals given by faculty, students, or guest artists from the School of Music at the University of Northern Iowa.

Perinatal Murine Cytomegalovirus Infection Reshapes The Transcriptional Profile And Functionality Of Nk Cells, Carmen Rožmanić, Eugene Park, Wayne M Yokoyama, Et Al.

2020-Current year OA Pubs

Infections in early life can elicit substantially different immune responses and pathogenesis than infections in adulthood. Here, we investigate the consequences of murine cytomegalovirus infection in newborn mice on NK cells. We show that infection severely compromised NK cell maturation and functionality in newborns. This effect was not due to compromised virus control. Inflammatory responses to infection dysregulated the expression of major transcription factors governing NK cell fate, such as Eomes, resulting in impaired NK cell function. Most prominently, NK cells from perinatally infected mice have a diminished ability to produce IFN-γ due to the downregulation of long non-coding RNA …

Scoping Potential Routes To Uk Civil Unrest Via The Food System: Results Of A Structured Expert Elicitation, A Jones, S Bridle, K Denby, R Bhunoo, D Morton, L Stanborough, B Coupe, V Pilley, T Benton, P Faloon, T Matthews, C Pettinger

School of Health Professions

We report the results of a structured expert elicitation to identify the most likely types of potential food system disruption scenarios for the UK, focusing on routes to civil unrest. We take a backcasting approach by defining as an end-point a societal event in which 1 in 2000 people have been injured in the UK, which 40% of experts rated as “Possible (20–50%)”, “More likely than not (50–80%)” or “Very likely (>80%)” over the coming decade. Over a timeframe of 50 years, this increased to 80% of experts. The experts considered two food system scenarios and ranked their plausibility …

Addressing Ambiguities In One Of Life’S Two Certainties: The New Jersey Law Revision Commission’S Examination Of Selected Tax Statutes, Laura C. Tharney, Samuel M. Silver, Whitney G. Schlimbach

Seton Hall Journal of Legislation and Public Policy

No abstract provided.

Widespread Dominance Of Methane Ebullition Over Diffusion In Freshwater Aquaculture Ponds, Renske J. E. Vroom, Sarian Kosten, Rafael M. Almeida, Raquel Mendonça, Ive S. Muzitano, Icaro Barbosa, Jonas Nasário, Ernandes S. Oliveira Junior, Alexander S. Flecker, Nathan Barros

School of Earth, Environmental, & Marine Sciences Faculty Publications

An ever-increasing demand for protein-rich food sources combined with dwindling wild fish stocks has caused the aquaculture sector to boom in the last two decades. Although fishponds are potentially strong emitters of the greenhouse gas methane (CH₄), little is known about the magnitude, pathways, and drivers of these emissions. We measured diffusive CH₄ emissions at the margin and in the center of 52 freshwater fishponds in Brazil. In a subset of ponds (n = 31) we additionally quantified ebullitive CH₄ fluxes and sampled water and sediment for biogeochemical analyses. Sediments (n = 20) were …

Next-Generation Crispr Gene-Drive Systems Using Cas12a Nuclease, Sara Sanz Juste, Emily M Okamoto, Christina Nguyen, Xuechun Feng, Víctor López Del Amo

Faculty, Staff and Student Publications

One method for reducing the impact of vector-borne diseases is through the use of CRISPR-based gene drives, which manipulate insect populations due to their ability to rapidly propagate desired genetic traits into a target population. However, all current gene drives employ a Cas9 nuclease that is constitutively active, impeding our control over their propagation abilities and limiting the generation of alternative gene drive arrangements. Yet, other nucleases such as the temperature sensitive Cas12a have not been explored for gene drive designs in insects. to address this, we herein present a proof-of-concept gene-drive system driven by Cas12a that can be regulated …

Vulnerability Of Elevation-Restricted Endemic Birds Of The Cordillera De Talamanca (Costa Rica And Panama) To Climate Change, Zhen Liu, Luis Sandoval, Lauren B. Sherman, Andrew M. Wilson

Neotropical Biodiversity

No abstract provided.

Pseudomonas Aeruginosa Kills Staphylococcus Aureus In A Polyphosphate-Dependent Manner, Ritika Sujit Shah

Theses and Dissertations

Due to their frequent coexistence in many polymicrobial infections, including in patients with wounds and cystic fibrosis, recent studies have started to investigate how the opportunistic pathogens Pseudomonas aeruginosa and Staphylococcus aureus interact with each other. P. aeruginosa rapidly outcompetes S. aureus under in vitro co-cultivation conditions, which is mediated by several of P. aeruginosa’s virulence factors. Here, we report that polyphosphate (polyP), an efficient stress defense system and virulence factor in P. aeruginosa, plays a role for the pathogen’s ability to inhibit and kill S. aureus in a contact-independent manner. We show that P. aeruginosa cells characterized by low …