Determinants Of Agro-Pastoralists’ Willingness To Pay For Improved Contagious Caprine Pleuropneumonia Vaccine In Kenya, Fredrick Ochieng Ouya, Eric Bett, Purity Nguhiu, Stella Makokha, Harrison Lutta, Willis Adero Abwao, Martin Mwirigi

All Peer-Reviewed Publications

Animal health care is critical for livestock production especially in arid and semi-arid areas where majority are agro-pastoralists. Contagious caprine pleuropneumonia (CCPP) is a highly contagious and fatal disease which commonly affects goats in arid and semi-arid areas. The government has been the major provider of CCPP vaccine and few large-scale farmers who are licensed and able to purchase directly from the vaccine producer. Although the vaccine is sold to farmers at a subsidized price by the government, its distribution has been characterized by scarcity, irregular and late administration by the authority concerned. It is envisioned that if the willingness …

Philanthropy’S Uneasy Journey Into Mental Health Grantmaking, Mallet R. Reid, Robert J. (Bob) Reid, Ximena Murillo, Anna Bobb

The Foundation Review

The increasing prevalence of mental illness and addiction in the United States has drawn considerable attention from grantmakers, which could catalyze the development and delivery of innovative approaches to these complex and difficult-to-treat behavioral health disorders. Relatively little is known, however, of the perspectives of these funders on how best to undertake this work.

To assist foundations in meaningful engagement with the field of behavioral health, this article shares the responses of 17 highly experienced behavioral health grantmakers to two research questions: What are the experiences of foundations that have funded behavioral health initiatives? What issues should be considered by …

Assessing Chondrocyte Viability Of Articular Cartilage Using Label-Free Imaging Methods, Hongming Fan

All Dissertations

ABSTRACT

Articular cartilage covers the ends of bones, providing a protective layer that can endure forces during movement. Chondrocytes, the only cell type found in articular cartilage, produce collagen fibers and proteoglycans that maintain the extracellular matrix (ECM). Cartilage damage impairs chondrocytes and their ability to maintain tissue stability. There are various factors that can cause cell death, which can be broadly classified into two categories: programmed cell death (apoptosis) and non-programmed cell death (necrosis). The consequences of cell death can have significant impacts on the extracellular matrix (ECM). The ECM is a complex network of proteins and carbohydrates that …

An In Vitro Platform To Characterize Myocardial Wound Remodeling, Jonathan Heywood

All Dissertations

Heart Failure, sometimes called Congestive Heart Failure, is a collection of pathological disruptions in which the heart is unable to pump blood properly. It affects over 6 million people in the United States, with the cost-per-patient at approximately $30,000 and the total cost estimated to be $160 billion by 2030. There is no single cause of heart failure, as it can manifest as a varying array of diseases, disorders, and syndromes. However, many of these underlying diseases result specifically from dysregulation of mechanically active cells called cardiac fibroblasts, which play a critical role in the remodeling of the extracellular matrix …

How Is Wildlife Poaching Changing In Uganda And How Can We Understand The Contribution Of Wildlife Protection Efforts At Multiple Scales: Murchison Falls National Park, Uganda., Ingrid Nyonza Nyakabwa

All Dissertations

Wildlife poaching is a critical global issue that poses significant threats to biodiversity, ecological balance, and the long-term sustainability of wildlife in Sub-Saharan Africa. The illicit trade in wildlife and their derivatives continues to grow, fueled by various socio-economic, cultural, and environmental factors. As the demand for wildlife products persists, it is imperative to understand the underlying causes, impacts, and potential solutions to combat this detrimental practice.

This research examined the dimensions of wildlife poaching in and around the area of Murchison Falls National Park in Uganda, the largest and oldest National Park in Uganda. Uganda has experienced success in …

A Burkean Herstory: Liminal Narratives In The Life And Work Of Kenneth Burke, Heather F. Hartness

All Dissertations

Women’s contributions to the world are mostly absent from the traditional historical narrative. Who is anonymous and what is invisible often proves challenging and difficult to imagine. We build our understanding of possibilities from what we learn, read, and see. Half of the world’s population accounting for less than one-fifth of historical narratives indicates a liminal chasm; notable people are missing from history. Time marches on, and if the contributions of historically marginalized people continue to be silenced, their contributions will continue to be invisible and unvalued. Histories and herstories are not neutral accounts. Even though most histories are partial, …

Delineating The Impact Of Vascular Smooth Muscle Cell Abca1/G1 And Mir-33a Expression On Atherosclerosis, Olanrewaju Oladosu

All Dissertations

Atherosclerotic cardiovascular disease is the leading cause of mortality worldwide due to being the predominant factor in heart attack and stroke deaths. Atherosclerotic cardiovascular disease is caused by cholesterol accumulating in arteries. It is historically thought that the cell type most responsible for causing atherosclerosis via excessive cholesterol accumulation is intimal monocyte-derived macrophages. However, macrophage-like cells (MLC) of vascular smooth muscle cell (VSMC) origin have now been proposed as another cell type to trigger atherosclerosis, since VSMC cholesterol accumulation results in these cells to trans-differentiate into a MLC phenotype. Three major genes involved in cholesterol metabolism are ABCA1, ABCG1, and …

Educational Robotics And Computational Thinking In Elementary School Students, Sonia D. Jordan

Electronic Theses and Dissertations

This study examined the role of educational robotics in fostering computational thinking in elementary settings, both in classrooms and extracurricular programs. Among growing concerns over K–12 students’ computational thinking deficits, the research evaluated the impact of Lego EV3 and VEX IQ platforms. Data was sourced from lesson plans, student work surveys, and teacher interviews and then subjected to thematic analysis using a qualitative approach. The participants were Texas educators engaged in robotics instruction, even though specific robotics statistics are absent in the Texas Education Agency. Instructional strategies varied from hands-on experiences to translating mathematical concepts into robotic actions. A key …

Coopen: An Open Innovation Process Triggering Collaboration Between Ngos And Innovators In Africa — The Case Of Fondazione Cariplo And Fondazione Compagnia Di San Paolo, Fulvio Bersanetti, Alessandro Masciadri, Ilaria Caramia, Cristina Toscano

The Foundation Review

This article explores how the two main Italian foundations of banking origin, Fondazione Cariplo and Fondazione Compagnia di San Paolo, are internationally contributing to the United Nations Sustainable Development Goals agenda through Coopen, a cross-fertilization process between nonprofit organizations and the innovation ecosystem.

Guided by the United Nations 2030 Agenda’s Sustainable Development Goals, which identify innovation as a focal point in SDG 9, the foundations recognize the value that product, process, and methodological innovation can bring to Italy’s international development cooperation sector and its partnerships.

Coopen encourages the development and implementation of innovative solutions in Africa to respond to specific …

An Integrative Approach To Managing A Species Of Conservation Concern: Resource Selection, Spatial Ecology, And Population Genetics Of The Green Salamander (Aneides Aeneus), Megan Novak

All Dissertations

The relationship between wildlife and the environment they inhabit is dependent on both spatial and temporal scales. It is therefore crucial that biological investigations account for ecological scale when analyzing patterns and processes established, particularly when such investigations inform conservation management plans. This dissertation provides extensive insight into the conservation biology of the green salamander (Aneides aeneus), a critically imperiled species in South Carolina. The green salamander is a species that exists in a patchy network of rock outcrops within mountainous forest landscapes, and most studies on habitat suitability for green salamanders have been conducted on the macrohabitat, …

Understanding The Interaction Of Environmental Contaminants With Polystyrene Nanoparticles And Dna Using Nuclear Magnetic Resonance Spectroscopy And Density Functional Theory, Saduni Arachchi

All Dissertations

The objective of the thesis is to study the effect of environmental pollutants on polystyrene nanoparticles and biomolecules. This is done in two different techniques, particularly NMR and density functional theory. In this thesis, we use a combination of 1H NMR, Saturation-Transfer Difference (STD) NMR and relaxation experiments to study the interactions, kinetics and dynamics of antibiotics with polystyrene nanoparticles. (PS NPs) Density functional theory (DFT) is used to study the binding of commonly used non-oxidative hair dyes to biomolecules (DNA and amino acids) and PS particles.

The Pacifican December 2023, University Of The Pacific

All Issues - Student Newspaper, The Pacifican, Pacific Weekly

No abstract provided.

Estimating The Chemical Composition Of Secondary Compounds Of Iraqi Wild Agaricus Bellaniae Characterized Morphologically And Genetically, Ziena M. Abdul-Qader, Rukiabaa A. Chechan, Sudad K.M. Al-Taweel

Baghdad Science Journal

This study, which is considered the first of its kind in the world and the Arab homeland, was carried out in the laboratory of mushroom production belonging to the Medicinal Plant Unit/ College Of Agricultural Engineering Sciences/ University of Baghdad during the period from July 21, 2016, to December 30, 2018, aiming to isolate and purify the mycelium of the wild isolation in addition to the genetic and morphological identification of the mushroom Agaricus bellaniae. The obtained pure isolation was tagged in the American National Center for Biotechnology Information (NCBI) with symbol MF987843.1, thus Iraq would be the second country …

Control Pepper Fusarium Wilting By Biocontrol Agent Trichoderma Harzianum And Chelated Iron Fe-Eddha, Ali Nasser Ali Al-Aamel, Bushra Subair Abdulsada Al-Maliky

Baghdad Science Journal

Sweet pepper (Capsicum annuum L.) is an economically important vegetable crop. Wilt disease caused by Fusarium oxysporum f. sp. capsici is a specific pathogen that affects the pepper. Four isolates of F. oxysporum f. sp. capsici Fo3, Fo6, Fo7 and Fo8 were obtained from diseased pepper plants that were collected from different pepper fields in Baghdad. Fo6 isolate that has high pathogenicity to pepper seeds, Trichoderma harzianum (Th) was tested in vitro against F. oxysporum f. sp. capsici showed a high inhibition rate for the isolate Fo6, the concentration of chelated iron Fe-EDDHA 0.5% reduced the radial growth of Fo6 …

Numerical Investigation Of Physical Parameters In Cardiac Vessels As A New Medical Support Science For Complex Blood Flow Characteristics, Defrianto, Toto Saktioto, Yan Soerbakti, Andika Thoibah, Bunga Meyzia, Romi Fadli Syahputra, Okfalisa, Syamsudhuha, Dedi Irawan, Haryana Hairi

Baghdad Science Journal

This study proposes a mathematical approach and numerical experiment for a simple solution of cardiac blood flow to the heart's blood vessels. A mathematical model of human blood flow through arterial branches was studied and calculated using the Navier-Stokes partial differential equation with finite element analysis (FEA) approach. Furthermore, FEA is applied to the steady flow of two-dimensional viscous liquids through different geometries. The validity of the computational method is determined by comparing numerical experiments with the results of the analysis of different functions. Numerical analysis showed that the highest blood flow velocity of 1.22 cm/s occurred in the center …

Taxonomic And Morphological Studies On The Genus Chrotogonus Serville, 1838 (Pyrgomorphidae: Orthoptera) From Pakistan, With Reference To Their Habitats, Samiullah Soomro, Riffat Sultana

Baghdad Science Journal

Species of genus Chrotogonus (surface grasshoppers) are phytophagous and damaging to various economical important plants in their seedling stages. In order to know the biodiversity of surface grasshoppers, the detailed study has been conducted from four provinces of Pakistan. During this study, biodiversity, taxonomy, diagnosis, morphometric analysis, habitat, global distribution, and remarks of each species have been described. Total of 826 specimens were collected and sorted out into three species and three subspecies: C. (Chrotogonus) homalodemus homalodemus (Blanchard, 1836), C. (Chrotogonus) homalodemus (Blanchard, 1836), C. (Chrotogonus) trachypterus trachypterus (Blanchard, 1836), C. (Chrotogonus) trachypterus robertsi Kirby, 1914, C. (Chrotogonus) trachypterus (Blanchard, …

Determining Ace-2 Level And Some Relevant Biochemical Parameters And Studying The Effect Of Gender In Iraqi Diabetic Patients With Glomeruli And Renal Tubules Fibrosis As Early Prediction Marker, Reham Khuldon Ibrahim, Kadhim K. Ghudhaib, Ali Abdulmajid Dyab Allawi

Baghdad Science Journal

Diabetic kidney disease is an illness of the glomerulus that interferes with the glomerular filtration barrier (GFB), which is worked to enable kidney to selective purification of water and solutes in addition to limiting the movement of large macromolecules such as albumin. In the glomerular endothelium, mesangial cells, foot cells, and the brush border of the proximal tubules, ACE-2 is expressed and that the kidneys represent the highest-expressing region of this enzyme. Thus, the current study aimed to evaluate ACE-2 level in this case compared to healthy condition. The study Conducted with 120 male and female ranging in age (30-65) …

Solving The Hotdog Problem By Using The Joint Zero-Order Finite Hankel - Elzaki Transform, Roqia Khaled Rdwan, Mohammed Mahmoud Amer

Baghdad Science Journal

This paper is concerned with combining two different transforms to present a new joint transform FHET and its inverse transform IFHET. Also, the most important property of FHET was concluded and proved, which is called the finite Hankel – Elzaki transforms of the Bessel differential operator property, this property was discussed for two different boundary conditions, Dirichlet and Robin. Where the importance of this property is shown by solving axisymmetric partial differential equations and transitioning to an algebraic equation directly. Also, the joint Finite Hankel-Elzaki transform method was applied in solving a mathematical-physical problem, which is the Hotdog Problem. A …

A Study Of Policies And Responses To Chronically Absent Students In Illinois High Schools In The Four Southern Most Regions Of The Illinois Associaiton Of School Administrators, Charles Shain Crank

Dissertations

No abstract

Festival Of Christmas (2023), St. Norbert College Music Department

Music Performances

SNC Music Department presents: the Festival of Christmas Concert, featuring Concert Choir, Bell Choir, Chamber Choir, Concert Band, String Orchestra, Wind Ensemble, & the Jazz Ensemble (2023).

In Satan We Trust: The Satanic Temple’S Ongoing Crusade To Protect Abortion Rights, Bradley Koberg

Cardozo Law Review

In the summer of 2022, the Supreme Court overruled the nearly fifty-year-old precedent of Roe v. Wade, eliminating the constitutional right to an abortion. This was one of several decisions in which the newly minted conservative supermajority undermined what could be seen as progressive precedents. At the same time, the Court has been elevating religious liberty claims and strengthening legal protections for religious individuals and organizations (predominantly Christian). For anybody who cares about the “so-called separation of . . . church and state,” this conservative Christian reformation taking place in the nation’s highest court is a cause for concern.

However, …

Using Retrieval Practice, Variability, And Spacing To Facilitate Understanding Of Complex Information, Rachel Peirce

Arts & Sciences Graduate Student Theses and Dissertations

Combining the learning strategies of retrieval practice and variability has been shown to be effective in student learning (Butler et al., 2017; Pan & Rickard, 2018), but the temporal structuring of these learning strategies (i.e., massing versus spacing of practice) may benefit or hinder learning. Study 1 investigated whether the benefits of variable retrieval practice relative to repeated retrieval practice that occurs with massed practice extends to spaced practice. Participants watched geology videos that contained a total of 12 concepts, and then either answered three questions or read three study points about each concept. Each of the three questions and …

A New Era For Myelin Research In Neurofibromatosis Type 1, Peter De Blank, Akiko Nishiyama, Alejandro Lopez-Juarez

Health & Biomedical Sciences Faculty Publications

Evidence for myelin regulating higher-order brain function and disease is rapidly accumulating; however, defining cellular/molecular mechanisms remains challenging partially due to the dynamic brain physiology involving deep changes during development, aging, and in response to learning and disease. Furthermore, as the etiology of most neurological conditions remains obscure, most research models focus on mimicking symptoms, which limits understanding of their molecular onset and progression. Studying diseases caused by single gene mutations represents an opportunity to understand brain dys/function, including those regulated by myelin. Here, we discuss known and potential repercussions of abnormal central myelin on the neuropathophysiology of Neurofibromatosis Type …

Sonographic Characteristics And Pathology Correlation Of Breast Imaging Reporting And Data System (Bi-Rads) Category 4 Lesions, Poonum Khan, Imrana Masroor, Muhammad S Alam, Abdus Salam, Yasir Ali, Muhammad Salman Khan

Faculty, Staff and Student Publications

Introduction: The Breast Imaging-Reporting and Database System (BI-RADS) category 4 is designated for breast lumps that do not display the typical features of malignancy but still raise enough suspicion to warrant a recommendation for a biopsy, as malignancy cannot be ruled out through imaging alone. The main objective of this study was to investigate the sonographic characteristics and pathology correlation of BI-RADS 4 breast lesions and determine the positive predictive rate of BI-RADS 4 lesions in diagnosing breast cancer, using histopathology as the gold standard.

Methods: This was a cross-sectional study conducted at the Department of Radiology, Aga Khan University …

“Be Sustainable”: Eosc-Life Recommendations For Implementation Of Fair Principles In Life Science Data Handling, Romain David, Arina Rybina, Jean-Marie Burel, Jean-Karim Heriche, Pauline Audergon, Jan-Willem Boiten, Frederik Coppens, Sara Crockett, Katrina Exter, Sven Fahrner, Maddalena Fratelli, Carole Goble, Philipp Gormanns, Tobias Grantner, Björn Grüning, Kim Tamara Gurwitz, John M Hancock, Henriette Harmse, Petr Holub, Nick Juty, Geoffrey Karnbach, Emma Karoune, Antje Keppler, Jessica Klemeier, Carla Lancelotti, Jean-Luc Legras, Allyson L Lister, Dario Livio Longo, Rebecca Ludwig, Bénédicte Madon, Marzia Massimi, Vera Matser, Rafaele Matteoni, Michaela Th Mayrhofer, Christian Ohmann, Maria Panagiotopoulou, Helen Parkinson, Isabelle Perseil, Claudia Pfander, Roland Pieruschka, Michael Raess, Andreas Rauber, Audrey S Richard, Paolo Romano, Antonio Rosato, Alex Sánchez-Pla, Susanna-Assunta Sansone, Ugis Sarkans, Beatriz Serrano-Solano, Jing Tang, Ziaurrehman Tanoli, Jonathan Tedds, Harald Wagener, Martin Weise, Hans V Westerhoff, Rudolf Wittner, Jonathan Ewbank, Niklas Blomberg, Philip Gribbon

Faculty, Staff and Student Publications

The main goals and challenges for the life science communities in the Open Science framework are to increase reuse and sustainability of data resources, software tools, and workflows, especially in large-scale data-driven research and computational analyses. Here, we present key findings, procedures, effective measures and recommendations for generating and establishing sustainable life science resources based on the collaborative, cross-disciplinary work done within the EOSC-Life (European Open Science Cloud for Life Sciences) consortium. Bringing together 13 European life science research infrastructures, it has laid the foundation for an open, digital space to support biological and medical research. Using lessons learned from …

Systematic Analysis Of Proximal Midgut- And Anorectal-Originating Contractions In Larval Zebrafish Using Event Feature Detection And Supervised Machine Learning Algorithms, Ryan M Cassidy, Erika M Flores, Anh K Trinh Nguyen, Sai S Cheruvu, Rosa A Uribe, Anne Marie Krachler, Max A Odem

Faculty, Staff and Student Publications

Background: Zebrafish larvae are translucent, allowing in vivo analysis of gut development and physiology, including gut motility. While recent progress has been made in measuring gut motility in larvae, challenges remain which can influence results, such as how data are interpreted, opportunities for technical user error, and inconsistencies in methods.

Methods: To overcome these challenges, we noninvasively introduced Nile Red fluorescent dye to fill the intraluminal gut space in zebrafish larvae and collected serial confocal microscopic images of gut fluorescence. We automated the detection of fluorescent-contrasted contraction events against the median-subtracted signal and compared it to manually annotated gut contraction …

Cbx4 Promotes Antitumor Immunity By Suppressing Pdcd1 Expression In T Cells, Liwei Ren, Ziyin Li, Yu Zhou, Jun Zhang, Ziheng Zhao, Zhaofei Wu, Ye Zhao, Yurong Ju, Xuewen Pang, Xiuyuan Sun, Wei Wang, Yu Zhang

Faculty, Staff and Student Publications

E3 SUMO-protein ligase CBX4 (CBX4), a key component of polycomb-repressive complexes 1 (PRC1), has been reported to regulate a variety of genes implicated in tumor growth, metastasis, and angiogenesis. However, its role in T-cell-mediated antitumor immunity remains elusive. To shed light on this issue, we generated mice with T-cell-specific deletion of Cbx4. Tumor growth was increased in the knockout mice. Additionally, their tumor-infiltrating lymphocytes exhibited impaired tumor necrosis factor-alpha (TNF-α) and interferon-gamma (IFN-γ) production, with an elevated programmed cell death protein 1 (PD-1) level. In fact, dysregulated Pdcd1 expression was observed in all major subsets of peripheral T cells from …

A Comprehensive Assessment Of Anthropogenic And Natural Sources And Sinks Of Australasia's Carbon Budget, Yohanna Villalobos, Josep G. Canadell, Elizabeth D. Keller, Peter R. Briggs, Beata Bukosa, Donna L. Giltrap, Ian Harman, Timothy W. Hilton, Miko U. F. Kirschbaum, Ronny Lauerwald, Liyin L. Liang, Taylor Maavara, Sara E. Mikaloff-Fletcher, Peter J. Rayner, Laure Resplandy, Judith Rosentreter, Eva M. Metz, Oscar Serrano, Benjamin Smith

Research outputs 2022 to 2026

Regional carbon budget assessments attribute and track changes in carbon sources and sinks and support the development and monitoring the efficacy of climate policies. We present a comprehensive assessment of the natural and anthropogenic carbon (C-CO2) fluxes for Australasia as a whole, as well as for Australia and New Zealand individually, for the period from 2010 to 2019, using two approaches: bottom-up methods that integrate flux estimates from land-surface models, data-driven models, and inventory estimates; and top-down atmospheric inversions based on satellite and in situ measurements. Our bottom-up decadal assessment suggests that Australasia's net carbon balance was close to carbon …

Nutritional Strategies To Optimise Musculoskeletal Health For Fall And Fracture Prevention: Looking Beyond Calcium, Vitamin D And Protein, James Webster, Jack Dalla Via, Christina Langley, Cassandra Smith, Craig Sale, Marc Sim

Research outputs 2022 to 2026

Falls and osteoporotic fractures are a major public health problem, particularly among older adults. A third of individuals aged 65 years and over fall at least once each year, with up to 20 % of these resulting in serious injury, including fracture. In conjunction with regular exercise, the importance of diet for musculoskeletal health has largely focused upon calcium, vitamin D, and protein, particularly in the context of preventing falls and fractures. Whilst there is evidence for the benefits of these nutrients for musculoskeletal health, other aspects of the diet remain largely underexplored. For example, vegetables are rich sources of …

Protecting Brazilian Amazon Indigenous Territories Reduces Atmospheric Particulates And Avoids Associated Health Impacts And Costs, Paula R. Priest, Florencia Sangermano, Allison Bailey, Victoria Bugni, María Del Carmen Villalobos-Segura, Nataly Pimiento-Quiroga, Peter Daszak, Carlos Zambrana-Torrelio

Geography

Indigenous territories are considered important for conservation, but little is known about their role in maintaining human health. Here we quantified the potential human health and economic benefits of protecting these territories in the Brazilian Amazon, by using cardiovascular and respiratory diseases cases, pollutant and forest cover data. Between 2010 and 2019, 1.68 tons of Particulate Matter of small size (PM_2.5) were released every year, with negative effects for human health. A lower number of infections was also found in municipalities with more forested areas, and with a low level of fragmentation, which probably is related to the …