Digital Commons Network^™

Dietary Strawberries Improve Serum Metabolites Of Cardiometabolic Risks In Adults With Features Of The Metabolic Syndrome In A Randomized Controlled Crossover Trial, Arpita Basu, Kenneth Izuora, Andrew Hooyman, Hal R. Scofield, Jeffrey L. Ebersole

Physical Therapy Faculty Articles and Research

Dietary strawberries have been shown to improve cardiometabolic risks in multiple clinical trials. However, no studies have reported effects on serum metabolomic profiles that may identify the target pathways affected by strawberries as underlying mechanisms. We conducted a 14-week randomized, controlled crossover study in which participants with features of metabolic syndrome were assigned to one of the three arms for four weeks separated by a one-week washout period: control powder, 1 serving (low dose: 13 g strawberry powder/day), or 2.5 servings (high dose: 32 g strawberry powder/day). Blood samples, anthropometric measures, blood pressure, and dietary and physical activity data were …

Utilizing Drones To Streamline Wildlife Hazard Management Efforts By Airport Operators, Flavio A. C. Mendonca Ph.D., Ryan Wallace, Jose Cabrera, Cole Mcnall

National Training Aircraft Symposium (NTAS)

Airports operating under the Code of Federal Regulations Part 139 should conduct a wildlife hazard assessment (WHA) when some wildlife-strike events have occurred at or near the airport. The WHA must be conducted by a Qualified Airport Wildlife Biologist (QAWB). The required elements in a WHA include the identification of the wildlife species observed and their numbers, and the location of features on and near the airport that could attract wildlife. Service learning and research projects enable undergraduate students to develop transferable skills that are highly valued by the aviation industry, including critical thinking, self-confidence, the ability to integrate theory …

Improved Feedback Mechanisms Of The Hydraulics Sandbox Simulator, Karen J. Johnson, Martin Hebel

National Training Aircraft Symposium (NTAS)

The proposed presentation will include the following project and results from implementation in an aircraft hydraulic systems course.

In 2020 we developed a digital hydraulics system schematic sandbox for use in an FAA Part 147 airframe maintenance technician training program (See Figure 1). The sandbox allows students to drag-drop-connect components used in systems such as those found in aircraft. It allows them to ‘test-connect’ the components to get feedback on correct and incorrect ‘construction’. As shown in Figure 1, light green ‘hoses’ are correct supply connections, dark green are correct return connections and red are incorrect connections per established rules …

556 U.S. 662

Civil Matter Files

No abstract provided.

Ashcroft V. Iqbal

Civil Matter Files

No abstract provided.

The Adaptive Capacity To Implement Climate Migration Policy In Response To Sea-Level Rise In The Maldives, Kelsey Garrett

Capstone Collection

This exploratory study is centered on the increasing harmful impacts of climate change and its connection to human life. The effects are exacerbating the current drivers of migration like livelihoods, security, and politics. People are losing their homes and livelihoods because of drought, rising seas, or increasing natural disasters. Millions of people are. Displaced by climate events every year, the number is expected to increase. Due to this, there is value in studying climate change and migration. Amongst the most vulnerable are those living in Small Island Developing States (SIDS). This exploratory study examined the Maldives to understand their adaptive …

Static And Dynamic Analysis Of A Bistable Frequency Up-Converter Piezoelectric Energy Harvester, Mohammad Atmeh, Alwathiqbellah Ibrahim, Abdallah Ramini

Mechanical Engineering Faculty Publications and Presentations

Using energy harvesting to convert ambient vibrations efficiently to electrical energy has become a worthy concept in recent years. Nevertheless, the low frequencies of the ambient vibrations cannot be effectively converted to power using traditional harvesters. Therefore, a frequency up-conversion harvester is presented to convert the low-frequency vibrations to high-frequency vibrations utilizing magnetic coupling. The presented harvester consists of a low-frequency beam (LFB) and a high-frequency beam (HFB) with identical tip magnets facing each other at the same polarity. The HFB, fully covered by a piezoelectric strip, is utilized for voltage generation. The dynamic behavior of the system and the …

Issue 410: January 19-February 2, 2023, The Local Voice

The Local Voice

Townies Favorites 2023

Trisomy 21 Induces Pericentrosomal Crowding Delaying Primary Ciliogenesis And Mouse Cerebellar Development., Cayla E Jewett, Bailey L Mccurdy, Eileen T O'Toole, Alexander J Stemm-Wolf, Katherine S Given, Carrie H Lin, Valerie Olsen, Whitney Martin, Laura G Reinholdt, Joaquín M Espinosa, Kelly D Sullivan, Wendy B Macklin, Rytis Prekeris, Chad G Pearson

Faculty Research 2023

Trisomy 21, the genetic cause of Down syndrome, disrupts primary cilia formation and function, in part through elevated Pericentrin, a centrosome protein encoded on chromosome 21. Yet how trisomy 21 and elevated Pericentrin disrupt cilia-related molecules and pathways, and the in vivo phenotypic relevance remain unclear. Utilizing ciliogenesis time course experiments combined with light microscopy and electron tomography, we reveal that chromosome 21 polyploidy elevates Pericentrin and microtubules away from the centrosome that corral MyosinVA and EHD1, delaying ciliary membrane delivery and mother centriole uncapping essential for ciliogenesis. If given enough time, trisomy 21 cells eventually ciliate, but these ciliated …

The Indiana Statesman, January 19, 2023, Indiana State University

Student Newspaper

New section debuts for the Statesman; Bingo begins again; ISU celebrates MLK day with service; Child molester pleads guilty; Founders Day celebration set for end of January

Usage Statistics: Project Counter R5 Dr_D1 Report Fy2022 - Database Search And Item Usage, Andrée J. Rathemacher

Technical Services Reports and Statistics

Project COUNTER R5 Report DR_D1 for the University of Rhode Island for the period from July 1, 2021 - June 30, 2022. The DR_D1 report is defined as "Database Search and Item Usage." This report presents an annual total only and only includes those platforms successfully configured for automated harvesting via SUSHI.

File for download is Excel spreadsheet generated by Alma Analytics.

Results:

Searches Automated - 316,771

Searches Federated - 52,533

Searches Regular - 768,218

Total Item Investigations - 930,171

Total Item Requests - 251,936

The Student Movement Volume 107 Issue 12: Revisiting "The Dream": Students Celebrate Mlk Day, Grace No, Nora Martin, Gloria Oh, Ysabelle Fernando, Solana Campbell, Amelia Stefanescu, Brendan Oh, Julia Randall, Gabriela Francisco, Peter Lyons, Anthony Bosman, Martin Hanna, Ryan T. Hayes, Karin Thompson, Melissa Moore, Wambui Karanja, Desmond H. Murray, Scott Moncrieff

The Student Movement v. 107 (2022-2023)

HUMANS

Andrews Gaming Club, Interviewed by: Grace No

Meet Gio Lee, Interviewed by: Nora Martin

New Year, Happier Me, Gloria Oh

ARTS & ENTERTAINMENT

Art @ AU: Harrigan's Gallery, Ysabelle Fernando

Currently: The Way of Water, Solana Campbell

Ode to 2022, Amelia Stefanescu

Where Do I Find God - Part I, Anonymous

NEWS

Honoring Martin Luther King Jr.'s Legacy, Brendan Oh

Is America Safe?: First Grader Shoots Teacher, Julia Randall

A House Divided: Current Issues Within the School of Architecture and Interior Design, Student Movement Editorial Staff

IDEAS

Harry & Meghan: Unpacking Royal Pains, Gabriela Francisco

A New Space for …

Researchers Find That Chromatically Simulated Myopic Blur May Be Useful As A Myopia Control Therapy, Anna Jones

Browse All News

No abstract provided.

The Murder Of George Floyd: A Case Study Examining How The Policing Of Black Men And Grassroots Activism Influence The Will Of Black Women To Lead, Ella Gates-Mahmoud

Doctorate in Education

This study's objective investigates the viewpoints held by Black women in two urban areas of Minnesota about the social upheaval that followed the murder of George Floyd in 2020 for using a counterfeit $20 bill. In the last decade, police killings of innocent Black people in the United States have received more attention, and Floyd's death is only one example of this phenomenon. In the U.S., the likelihood of a police officer taking the life of a Black man is higher than that of a White man. Between 2013-2019 there have been 1,641 fatal shootings of defenseless Black men by …

The Association Between Civic Engagement Via Participatory Art And Adolescents’ Self-Esteem And Self-Efficacy, Michaela Ann Hayes

Theses and Dissertations

Civic engagement refers to actions taken by individuals to address issues of public concern, which can come in many forms including engagement in art. Participation in these activities can have positive impacts on the individual, including improved mental and physical health, as well as on the community through increased appreciation for differences and acquisition of values such as tolerance. The Bioecological Model suggests that an individual's participation in civic activities is influenced by the various levels of their environment. These experiences may be particularly impactful for adolescents. Indeed, adolescents who participated in civic engagement activities have been found to have …

The Inbio Barcoding Initiative Database: Dna Barcodes Of Iberian Trichoptera, Documenting Biodiversity For Freshwater Biomonitoring In A Mediterranean Hotspot, Joana Pauperio, Luis Martin Gonzalez, Jesus Martinez, Marcos A. González, Filipa Ms Martins, Joana Veríssimo, Pamela Puppo, Joana Pinto, Cátia Chaves, Catarina J. Pinho, José Manuel Grosso-Silva, Lorenzo Quaglietta, Teresa Luísa L. Silva, Pedro Sousa, Paulo Celio Alves, Nuno Fonseca, Pedro Beja, Sónia Ferreira

Biological Sciences Faculty Research

Background

The Trichoptera are an important component of freshwater ecosystems. In the Iberian Peninsula, 380 taxa of caddisflies are known, with nearly 1/3 of the total species being endemic in the region. A reference collection of morphologically identified Trichoptera specimens, representing 142 Iberian taxa, was constructed. The InBIO Barcoding Initiative (IBI) Trichoptera 01 dataset contains records of 438 sequenced specimens. The species of this dataset correspond to about 37% of Iberian Trichoptera species diversity. Specimens were collected between 1975 and 2018 and are deposited in the IBI collection at the CIBIO (Research Center in Biodiversity and Genetic Resources, Portugal) or …

Virome Analysis And Association Of Positive Coxsackievirus B Serology During Pregnancy With Congenital Heart Disease, Mathieu Garand, Susie S Y Huang, Lisa S Goessling, Fei Wan, Donna A Santillan, Mark K Santillan, Anoop Brar, Todd N Wylie, Kristine M Wylie, Pirooz Eghtesady

2020-Current year OA Pubs

BACKGROUND: We have previously shown coxsackievirus B (CVB) to be a potent inducer of congenital heart disease (CHD) in mice. The clinical relevance of these findings in humans and the roles of other viruses in the pathogenesis of CHD remain unknown.

METHODS: We obtained plasma samples, collected at all trimesters, from 89 subjects (104 pregnancies), 73 healthy controls (88 pregnancies), and 16 with CHD-affected birth (16 pregnancies), from the Perinatal Family Tissue Bank (PFTB). We performed CVB IgG/IgM serological assays on plasma. We also used ViroCap sequencing and PCR to test for viral nucleic acid in plasma, circulating leukocytes from …

Rogue Entrepreneurship, Russ Mcbride, Mark D. Packard, Brent B. Clark

Marketing & Entrepreneurship Faculty Publications

We suggest a new category of “rogue entrepreneurship,” that describes entrepreneurial activity where the core business idea violates established or expert consensus, to be contrasted with “conforming entrepreneurship,” where it does not. There are large entrepreneurial rents hidden behind a bulwark of expert consensus that predicts doom for a venture based upon a rogue and unlikely claim. The “rogue” cases, where the predominant assessment context is different from the entrepreneur’s, result in broad skepticism against the entrepreneurial claim. We explain what rogue entrepreneurship is and how it works.

“What important truth do very few people agree with you on? A …

Investigating Stigma During The Early Stages Of A Pandemic Through The Lens Of Covid-19, Zach Thornton, Bethany Hodge, Sheridan Langford

The University of Louisville Journal of Respiratory Infections

Background: Individuals face stigma associated with numerous health conditions. Stigma can arise rapidly during the early spread of a new disease, adding to the burden felt by those affected. COVID-19 can be used as an example to study stigma during the early phases of a pandemic. This narrative review is a descriptive analysis that tracks the ways in which COVID-19 stigma was discussed in the scholarly literature during the first year of the pandemic to understand how stigma was viewed in the context of a rapidly spreading pandemic.

Methods: PubMed was used as a non-exhaustive sample of the literature. Searches …

Usage Statistics: Project Counter R5 Tr_B1 Report Fy2022 - Book Requests (Excluding Oa_Gold) By Title, Andrée J. Rathemacher

Technical Services Reports and Statistics

Project COUNTER R5 Report TR_B1 for the University of Rhode Island for the period from July 1, 2021 - June 30, 2022. The TR_B1 report is defined as "Book Requests (Excluding OA_Gold)." This report presents an annual total only and only includes those platforms successfully configured for automated harvesting via SUSHI.

File for download is Excel spreadsheet generated by Alma Analytics.

Results:

Total Item Requests - 92,619

Unique Title Requests - 43,012

Usage Statistics: Project Counter R5 Ir_M1 Report Fy2022 - Multimedia Item Requests, Andrée J. Rathemacher

Technical Services Reports and Statistics

Project COUNTER R5 Report IR_M1 for the University of Rhode Island for the period from July 1, 2021 - June 30, 2022. The IR_M1 report is defined as "Multimedia Item Requests." This report presents an annual total only and only includes those platforms successfully configured for automated harvesting via SUSHI.

File for download is Excel spreadsheet generated by Alma Analytics.

Results:

Total Item Requests - 4,309

Usage Statistics: Project Counter R5 Tr_J1 Report Fy2022 - Journal Requests (Excluding Oa_Gold) By Title, Andrée J. Rathemacher

Technical Services Reports and Statistics

Project COUNTER R5 Report TR_J1 for the University of Rhode Island for the period from July 1, 2021 - June 30, 2022. The TR_J1 report is defined as "Journal Requests (Excluding OA_Gold)." This report presents an annual total only and only includes those platforms successfully configured for automated harvesting via SUSHI.

File for download is Excel spreadsheet generated by Alma Analytics.

Results:

Total Item Requests - 771,947

Unique Item Requests - 578,437

Development Of Food-Based Recommendation And Nutrient-Dense Meal For Female Shift Workers In West Java, Indonesia, Shanti Puji Lestari, Nuri Purwito Adi, Umi Fahmida, Dian Kusuma Dewi, Muchtaruddin Mansyur

Occupational and Environmental Medicine Journal of Indonesia

Introduction. Some manufacturing industries employ not only male workers but also female workers, who are required to undergo shift work. Given the altered eating habits as well as metabolic and endocrine profiles of shift workers, this will affect their nutritional needs. Considering that anemia that occurs in female workers is primarily nutritional anemia, this becomes a challenge in the field of occupational nutrition, especially in terms of preparing food for female workers in accordance with their nutritional needs. The aim of the study is to develop a set of FBR for female shift workers using the Linear Programming (LP) approach. …

Pgc-1Α Senses The Cbc Of Pre-Mrna To Dictate The Fate Of Promoter-Proximally Paused Rnapii, Xavier Rambout, Hana Cho, Roméo Blanc, Qing Lyu, Joseph M Miano, Joe V Chakkalakal, Geoffrey M Nelson, Hari K Yalamanchili, Karen Adelman, Lynne E Maquat

Children’s Nutrition Research Center Staff Publications

PGC-1α is well established as a metazoan transcriptional coactivator of cellular adaptation in response to stress. However, the mechanisms by which PGC-1α activates gene transcription are incompletely understood. Here, we report that PGC-1α serves as a scaffold protein that physically and functionally connects the DNA-binding protein estrogen-related receptor α (ERRα), cap-binding protein 80 (CBP80), and Mediator to overcome promoter-proximal pausing of RNAPII and transcriptionally activate stress-response genes. We show that PGC-1α promotes pausing release in a two-arm mechanism (1) by recruiting the positive transcription elongation factor b (P-TEFb) and (2) by outcompeting the premature transcription termination complex Integrator. Using mice …

Utilizing Neoantigen-Specific Cd4* T Cells And Immune Checkpoint Modulation To Advance Adoptive Cell Therapy With Tumor-Infiltrating Lymphocytes For Metastatic Melanoma Patients, Maclean Scott Hall

USF Tampa Graduate Theses and Dissertations

Adoptive cell therapy (ACT) with tumor-infiltrating lymphocytes (TIL) is a promising immunotherapeutic approach for patients with advanced solid tumors. Metastatic melanoma is a tumor type amenable to immunotherapy in part due to the presence of antigen-specific TIL. These T cells can be activated and expanded for ACT, which has resulted in relatively high rates of clinical responses. While numerous advances have been made, the inclusion of neoantigen-specific CD4+ T cells within TIL infusion products remains underexplored and therefore offers a significant opportunity for progress. Similarly, immune checkpoint inhibitors, specifically PD-1 blocking antibodies, augment antitumor immunity and may improve the outcomes …

2023 January 19 - From My Notepads Newsletter, Office Of The President, East Tennessee State University, Brian Noland

From My Notepads: A Newsletter from President Brian Noland

No abstract provided.

Semi-Quantitative Detection Of Pseudouridine Modifications And Type I/Ii I/Ii Hypermodifications In Human Mrnas Using Direct Long-Read Sequencing, Sepideh Tavakoli, Mohammad Nabizadeh, Amr Makhamreh, Howard Gamper, Caroline A Mccormick, Neda K Rezapour, Ya-Ming Hou, Meni Wanunu, Sara H Rouhanifard

Department of Biochemistry and Molecular Biology Faculty Papers

Here, we develop and apply a semi-quantitative method for the high-confidence identification of pseudouridylated sites on mammalian mRNAs via direct long-read nanopore sequencing. A comparative analysis of a modification-free transcriptome reveals that the depth of coverage and specific k-mer sequences are critical parameters for accurate basecalling. By adjusting these parameters for high-confidence U-to-C basecalling errors, we identify many known sites of pseudouridylation and uncover previously unreported uridine-modified sites, many of which fall in k-mers that are known targets of pseudouridine synthases. Identified sites are validated using 1000-mer synthetic RNA controls bearing a single pseudouridine in the center position, demonstrating systematic …

Board Of Mgrs. Of The Charleston Condominium V. Oppenheim

All Decisions

No abstract provided.

The Effect Of Alcohol On Lipid Membrane-Membrane Fusion And Snare Proteins, Robert E. Coffman

Theses and Dissertations

Currently the treatment of alcohol use disorder is very difficult and often requires the combination of therapy and medications, with many who undertake treatment experiencing relapse over time. There is also no treatment in use to prevent the development of alcohol use disorder. It is the aim of this work to provide information that may be useful for the development of a preventative treatment for developing alcohol use disorder by elucidating more of the acute effects of alcohol use. It is known that these effects originate in the brain. Within the brain are circuits made up of neurons that communicate …

Control Of Craniofacial Development By The Collagen Receptor, Discoidin Domain Receptor 2, Fatma F Mohamed, Chunxi Ge, Shawn A Hallett, Alec C Bancroft, Randy T Cowling, Noriaki Ono, Abdul-Aziz Binrayes, Barry Greenberg, Benjamin Levi, Vesa M Kaartinen, Renny T Franceschi

Faculty, Staff and Student Publications

Development of the craniofacial skeleton requires interactions between progenitor cells and the collagen-rich extracellular matrix (ECM). The mediators of these interactions are not well-defined. Mutations in the discoidin domain receptor 2 gene (DDR2), which encodes a non-integrin collagen receptor, are associated with human craniofacial abnormalities, such as midface hypoplasia and open fontanels. However, the exact role of this gene in craniofacial morphogenesis is not known. As will be shown, Ddr2-deficient mice exhibit defects in craniofacial bones including impaired calvarial growth and frontal suture formation, cranial base hypoplasia due to aberrant chondrogenesis and delayed ossification at growth plate …