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Additional Curricular Changes Proposed For 2023-2025 Morris Catalog Pt. 2, Curriculum Committee

Curriculum Committee Reports

No abstract provided.

Does The Osteopathic Pedal Pump Reduce Lower Limb Volume In Healthy Subjects?, Jill S. Adams, Sahil H. Parikh, Brandon J. Goodwin, Donald R. Noll

Rowan-Virtua School of Osteopathic Medicine Departmental Research

CONTEXT: Lymphatic treatments are gentle and passive techniques believed to enhance movement of lymph back into the central circulatory system. Animal studies provide supportive evidence, yet there are few studies in humans.

OBJECTIVES: The aim of this study is to investigate whether the osteopathic pedal pump protocol reduces volume in the lower limbs of healthy subjects.

METHODS: A total of 30 first- and second-year medical students were recruited. Subjects were excluded from participating if they had acute asthma, chronic obstructive pulmonary disease (COPD), congestive heart failure, active infections, fractures of the lower extremities, or metastatic cancer. A within-subjects study design …

Human Hematopoietic Stem Cell Engrafted Il-15 Transgenic Nsg Mice Support Robust Nk Cell Responses And Sustained Hiv-1 Infection., Shawn A Abeynaike, Tridu R Huynh, Abeera Mehmood, Teha Kim, Kayla Frank, Kefei Gao, Cristina Zalfa, Angel Gandarilla, Leonard D. Shultz, Silke Paust

Faculty Research 2023

Mice reconstituted with human immune systems are instrumental in the investigation of HIV-1 pathogenesis and therapeutics. Natural killer (NK) cells have long been recognized as a key mediator of innate anti-HIV responses. However, established humanized mouse models do not support robust human NK cell development from engrafted human hematopoietic stem cells (HSCs). A major obstacle to human NK cell reconstitution is the lack of human interleukin-15 (IL-15) signaling, as murine IL-15 is a poor stimulator of the human IL-15 receptor. Here, we demonstrate that immunodeficient NOD.Cg-Prkdcscid Il2rgtm1Wjl/SzJ (NSG) mice expressing a transgene encoding human IL-15 (NSG-Tg(IL-15)) have physiological levels of …

Faculty Senate Agenda, February 6, 2023, Utah State University

Faculty Senate & Faculty Senate Executive Committee

• Call to Order
  • Approval of Minutes
• University Business
• Faculty Senate Presidency Business
• Information
  • Educational Policies Committee
  • Export Control Policy
  • Policy 369 – Other Leave
• Reports
  • Professional Responsibilities & Procedures Committee Annual Report
  • Office of Research Annual Report
  • School of Graduate Studies Annual Report
  • Faculty Diversity, Development & Equity Annual Report
  • Faculty Composition AY 2021
• Old Business
• New Business
  • Committee to Investigate Divestment
  • Amend Agenda to include Faculty Senate President Reports
• Adjourn

Codebase Relationship Visualizer: Visualizing Relationships Between Source Code Files, Jesse Hines

MS in Computer Science Project Reports

Understanding relationships between files and their directory structure is a fundamental part of the software development process. However, it can be hard to grasp these relationships without a convenient way to visualize how files are connected and how they fit into the directory structure of the codebase. In this paper we describe CodeBase Relationship Visualizer (CBRV), a Visual Studio Code extension that interactively visualizes the relationships between files. CBRV displays the relationships between files as arrows superimposed over a diagram of the codebase's directory structure. CBRV comes bundled with visualizations of the stack trace path, a dependency graph for Python …

Integrating Multiliteracies In A Third Grade Classroom To Enhance Student Engagement And Motivation, Rebecca K. Mcdonough

Theses and Dissertations

The purpose of the study is to investigate the growth in student motivation and engagement through a multiliteracy lens. The specific aim is to explore what happens when a traditional writing unit is replaced with a multiliteracy writing unit that utilizes multimodal components. The students demonstrated changes in how they perceived themselves as writers and how they viewed writing in general. The implications for teaching writing with a multiliteracy approach is also discussed.

God Games: An Experimental Study Of Uncertainty, Superstition, And Cooperation, Aidin Hajikhameneh, Laurence R. Iannaccone

Economics Faculty Articles and Research

This paper uses a novel lab experiment to test claims about the origins and functions of religion. We modify the standard public goods game, adding a computer-based agent that adjusts earnings in ways that might depend on players' contributions. Our treatments employ three different descriptions of the adjustment process that loosely correspond to monotheistic, atheistic, and agnostic interpretations of the computer's role. The adjustments neither mask players' contributions nor magnify their impact. Yet players in all three adjustment treatments contribute much more than those who play the standard public goods game. Players' contributions and survey responses show that adjustments induce …

Soil Microbial Legacies Influence Freeze–Thaw Responses Of Soil, Melissa A. Pastore, Aimee T. Classen, Marie E. English, Serita D. Frey, Melissa A. Knorr, Karin Rand, E. Carol Adair

Faculty Publications

Warmer winters with less snowfall are increasing the frequency of soil freeze–thaw cycles across temperate regions. Soil microbial responses to freeze–thaw cycles vary and some of this variation may be explained by microbial conditioning to prior winter conditions, yet such linkages remain largely unexplored. We investigated how differences in temperature history influenced microbial community composition and activity in response to freeze–thaw cycles.

We collected soil microbial communities that developed under colder (high elevation) and warmer (low elevation) temperature regimes in spruce-fir forests, then added each of these soil microbial communities to a sterile bulk-soil in a laboratory microcosm experiment. The …

An American Freedom: The Intelligentsia And Freedom Of The Press After Blackstone, Matthew Schafer

Penn State Law Review (2003 - Present)

No abstract provided.

Accomplishments And Challenges Of The Research On Antillean Manatee: A Bibliometric Analysis, Delma Nataly Castelblanco-Martínez, Daniel Gonzalez-Socoloske, Leslie Cabrias, Natalia Garcés-Cuartas, Gloria Katerin Arévalo-González, João Carlos Gomes Borges, Miriam Marmontel

Faculty Publications

The Antillean manatee (Trichechus manatus manatus) is an endangered subspecies of the West Indian manatee inhabiting countries of South America, Meso America and the Caribbean. Basic and applied research is necessary to inform management plans for the effective recovery of this subspecies. The purpose of this study was to systematically review literature regarding Antillean manatees, without restriction of the research topic. Article selection and screening process are described. Our final database consisted of 456 publications, of which peer-reviewed literature (articles, reviews, and notes in research journals) represent the most important type (63.4%), followed by BSc, MSc, and PhD theses (28.1%). …

Gold Nanoparticle-Enhanced X-Ray Microtomography Of The Rodent Reveals Region-Specific Cerebrospinal Fluid Circulation In The Brain, Shelei Pan, Peter H Yang, Dakota Defreitas, Sruthi Ramagiri, Peter O Bayguinov, Carl D Hacker, Abraham Z Snyder, Jackson Wilborn, Hengbo Huang, Gretchen M Koller, Dhvanii K Raval, Grace L Halupnik, Sanja Sviben, Rui Tang, Gabriel Haller, James D Quirk, James A J Fitzpatrick, Prabagaran Esakky, Jennifer M Strahle, Et Al.

2020-Current year OA Pubs

Cerebrospinal fluid (CSF) is essential for the development and function of the central nervous system (CNS). However, the brain and its interstitium have largely been thought of as a single entity through which CSF circulates, and it is not known whether specific cell populations within the CNS preferentially interact with the CSF. Here, we develop a technique for CSF tracking, gold nanoparticle-enhanced X-ray microtomography, to achieve micrometer-scale resolution visualization of CSF circulation patterns during development. Using this method and subsequent histological analysis in rodents, we identify previously uncharacterized CSF pathways from the subarachnoid space (particularly the basal cisterns) that mediate …

Kenyon Collegiate - January 27, 2023

Kenyon Collegiate

No abstract provided.

Seeing In The Dark: A Review Of The Use Of Side-Scan Sonar To Detect And Study Manatees, With An Emphasis On Latin America, Daniel Gonzalez-Socoloske, León David Olivera-Gómez

Faculty Publications

Manatees are aquatic mammals that live in a variety of environments. Many of those shallow water environments have murky water, making detection using traditional visual surveys very challenging. Side-scan sonar was first proposed as a tool to detect and study manatees in these complicated habitats in 2005. Here, we summarize the use of this tool from 2005 to 2022 by searching the available literature. Our literature search revealed that this tool is being widely used in more than 20 locations and over 15 countries. All three manatee species are being studied with side-scan sonar. It is most useful in murky …

Discerning The Effect Of The Relationship Between Disclosure And Responsiveness On Depression, Anxiety, And Compassion Fatigue Among Veterinarians, Carrie Reif-Stice, Sarah Smith-Frigerio, Cheryl Auch Lawson, Steven Venette

Faculty Publications

OBJECTIVE

Previous scholarship has posited that veterinarians experience more anxiety, depression, and compassion fatigue symptoms than the general population. Disclosure of psychological stressors, combined with positive responsiveness, may reduce psychological symptoms. The goal of this study was to test the relationships between disclosure, responsiveness, compassion fatigue, anxiety, and depression.

SAMPLE

230 veterinarians from a private Facebook online support group.

PROCEDURES

Veterinarians from a private Facebook online support group were administered a cross-sectional survey using established scales measuring disclosure, responsiveness, compassion fatigue, anxiety, and depression. All scales reported strong reliability and validity.

RESULTS

Pearson correlations and mediation models were used to …

Hunting Behavior Of A Solitary Sailfish Istiophorus Platypterus And Estimated Energy Gain After Prey Capture, Ryan K. Logan, Sarah M. Luongo, Jeremy Vaudo, Bradley M. Wetherbee, Mahmood Shivji

Biology Faculty Articles

Foraging behavior and interaction with prey is an integral component of the ecological niche of predators but is inherently difficult to observe for highly mobile animals in the marine environment. Billfishes have been described as energy speculators, expending a large amount of energy foraging, expecting to offset high costs with periodic high energetic gain. Surface-based group feeding of sailfish, Istiophorus platypterus, is commonly observed, yet sailfish are believed to be largely solitary roaming predators with high metabolic requirements, suggesting that individual foraging also represents a major component of predator–prey interactions. Here, we use biologging data and video to examine daily …

Displaying And Delivering Viral Membrane Antigens Via Ww Domain–Activated Extracellular Vesicles, Sengjin Choi, Zhiping Yang, Qiyu Wang, Zhi Qiao, Maoyun Sun, Joshua Wiggins, Shi-Hua Xiang, Quan Lu

Nebraska Center for Virology: Faculty Publications

Membrane proteins expressed on the surface of enveloped viruses are conformational antigens readily recognized by B cells of the immune system. An effective vaccine would require the synthesis and delivery of these native conformational antigens in lipid membranes that preserve specific epitope structures. We have created an extracellular vesicle–based technology that allows viral membrane antigens to be selectively recruited onto the surface of WW domain–activated extracellular vesicles (WAEVs). Budding of WAEVs requires secretory carrier-associated membrane protein 3, which through its proline-proline-alanine-tyrosine motif interacts with WW domains to recruit fused viral membrane antigens onto WAEVs. Immunization with influenza and HIV viral …

Displaying And Delivering Viral Membrane Antigens Via Ww Domain–Activated Extracellular Vesicles, Sengjin Choi, Zhiping Yang, Qiyu Wang, Zhi Qiao, Maoyun Sun, Joshua Wiggins, Shi-Hua Xiang, Quan Lu

School of Veterinary and Biomedical Sciences: Faculty Publications

Membrane proteins expressed on the surface of enveloped viruses are conformational antigens readily recognized by B cells of the immune system. An effective vaccine would require the synthesis and delivery of these native conformational antigens in lipid membranes that preserve specific epitope structures. We have created an extracellular vesicle–based technology that allows viral membrane antigens to be selectively recruited onto the surface of WW domain–activated extracellular vesicles (WAEVs). Budding of WAEVs requires secretory carrier-associated membrane protein 3, which through its proline-proline-alanine-tyrosine motif interacts with WW domains to recruit fused viral membrane antigens onto WAEVs. Immunization with influenza and HIV viral …

Educational Policies Committee Agenda, February 2, 2023, Utah State University

Educational Policies Committee

• Approval of Minutes
• Subcommittee Reports
  • Curriculum Subcommittee
    • Course Approvals
  • Academic Standards Subcommittee
    • Minutes
  • General Education Subcommittee
    • Minutes
• Other Business
  • New English Prefix TCR
  • Research, Scholarship and Creative Inquiry (RSCI) Designation
• Adjourn

The Diamond, January 27, 2023, Dordt University

Dordt Diamond

• Front Page: Remembering Emma Nibbelink; Progress Through Collaboration; East Campus Apartments to Get New Appliances
• News: Increased Vandalism Prompts Mandatory Meeting; Goodbye Twosdays; Howard Wilson Retires
• Feature: Swimming into the Future; Winter Storms Impact
• Opinion: America's Health Literacy Crisis; Conservatives on Campus Need Coordination
• Art & Entertainment: The 13-Year Sequel - Avatar: The Way of Water Film Review; Puss in Boots: The Last Wish; Beloved Video Game "The Last of Us" Turned into Live-Action TV; The Art of War; First High School Art Exhibit to Begin March 1st; New Sports Broadcasting Class …

Integration Of Transcriptome-Wide Association Study With Neuronal Dysfunction Assays Provides Functional Genomics Evidence For Parkinson’S Disease Genes, Akash Tarkunde, Katy Fan Zhu, Alma Perez, Megan Mair, Justin Moore, Joshua M Shulman, Ismael Al-Ramahi, Juan Botas

Faculty, Staff and Students Publications

Genome-wide association studies (GWAS) have markedly advanced our understanding of the genetics of Parkinson's disease (PD), but they currently do not account for the full heritability of PD. In many cases it is difficult to unambiguously identify a specific gene within each locus because GWAS does not provide functional information on the identified candidate loci. Here we present an integrative approach that combines transcriptome-wide association study (TWAS) with high-throughput neuronal dysfunction analyses in Drosophila to discover and validate candidate PD genes. We identified 160 candidate genes whose misexpression is associated with PD risk via TWAS. Candidates were validated using orthogonal …

Digital Surveillance Of Covid-19: Privacy And Equity Considerations, Elaine Gibson, Cal Dewolfe, Ilana Luther

Canadian Journal of Law and Technology

In this paper, we examine the potentially deleterious effects of surveillance on vulnerable Canadians. A wide range of digital surveillance technologies have either been deployed or considered for deployment both in Canada and around the world in response to the international emergency created by the COVID-19 pandemic. Some of these technologies are highly effective in predicting or identifying individual cases and/or outbreaks; others assist in tracing contacts or enforcing compliance with quarantine and isolation measures. However, there are necessarily risks associated with their deployment. First are the infringements on privacy rights of citizens and groups. Second, these technologies run the …

Recognizing Operators’ Duties To Properly Select And Supervise Ai Agents – A (Better?) Tool For Algorithmic Accountability, Richard Zuroff

Canadian Journal of Law and Technology

In November of 2020, the Privacy Commissioner of Canada proposed creating GDPR-inspired rights for decision subjects and allowing financial penalties for violations of those rights. Shortly afterward, the proposal to create a right to an explanation for algorithmic decisions was incorporated into Bill C-11, the Digital Charter Implementation Act. This commentary proposes that creating duties for operators to properly select and supervise artificial agents would be a complementary, and potentially more effective, accountability mechanism than creating a right to an explanation. These duties would be a natural extension of employers’ duties to properly select and retain human employees. Allowing victims …

Vaccines Against Group B Coxsackieviruses And Their Importance, Kiruthiga Mone, Ninaad Lasrado, Meghna Sur, Jay Reddy

School of Veterinary and Biomedical Sciences: Faculty Publications

The group B coxsackieviruses (CVBs) exist in six serotypes (CVB1 to CVB6). Disease associations have been reported for most serotypes, and multiple serotypes can cause similar diseases. For example, CVB1, CVB3, and CVB5 are generally implicated in the causation of myocarditis, whereas CVB1 and CVB4 could accelerate the development of type 1 diabetes (T1D). Yet, no vaccines against these viruses are currently available. In this review, we have analyzed the attributes of experimentally tested vaccines and discussed their merits and demerits or limitations, as well as their impact in preventing infections, most importantly myocarditis and T1D.

Displaying And Delivering Viral Membrane Antigens Via Ww Domain–Activated Extracellular Vesicles, Sengjin Choi, Zhiping Yang, Qiyu Wang, Zhi Qiao, Maoyun Sun, Joshua Wiggins, Shi-Hua Xiang, Quan Lu

Nebraska Center for Virology: Faculty Publications

Membrane proteins expressed on the surface of enveloped viruses are conformational antigens readily recognized by B cells of the immune system. An effective vaccine would require the synthesis and delivery of these native conformational antigens in lipid membranes that preserve specific epitope structures. We have created an extracellular vesicle–based technology that allows viral membrane antigens to be selectively recruited onto the surface of WW domain–activated extracellular vesicles (WAEVs). Budding of WAEVs requires secretory carrier-associated membrane protein 3, which through its proline-proline-alanine-tyrosine motif interacts with WW domains to recruit fused viral membrane antigens onto WAEVs. Immunization with influenza and HIV viral …

The Double-Edged Sword Of Social Media Usage During The Covid-19 Pandemic: Demographical And Cultural Analyses, Khaled A. Alshare, Murad Moqbel, Mohammad I. Merhi

Information Systems Faculty Publications

Purpose

This exploratory research aims to (1) investigate the bright and dark sides of social media use during the COVID-19 pandemic; (2) explore the impact of demographic factors on social media usage; and (3) assess the effects of cultural dimensions on social media usage.

Design/methodology/approach

The data are collected through an online survey. Factors derived from grounded theories and models such as affordance theory and Hofstede's cultural framework were considered. Spearman correlation and nonparametric analysis were used to test the hypotheses.

Findings

The results revealed that social media usage was positively associated with healing and affiliation, and negatively associated with …

Regenerative Agriculture - A Literature Review On The Practices And Mechanisms Used To Improve Soil Health, Ravjit Khangura, David Ferris, Cameron Wagg, Jamie Bowyer

Natural Resources Research Articles

Conventional farming practices can lead to soil degradation and a decline in productivity. Regenerative agriculture (RA) is purported by advocates as a solution to these issues that focuses on soil health and carbon sequestration. The fundamental principles of RA are to keep the soil covered, minimise soil disturbance, preserve living roots in the soil year round, increase species diversity, integrate livestock, and limit or eliminate the use of synthetic compounds (such as herbicides and fertilisers). The overall objectives are to rejuvenate the soil and land and provide environmental, economic, and social benefits to the wider community. Despite the purported benefits …

Development Of De Novo Nonalcoholic Fatty Liver Disease Following Pancreatectomy, Vanisha Patel, Parth Shah, Daniel R. Ludwig, Chet W. Hammill, Motaz Ashkar

2020-Current year OA Pubs

De novo non-alcoholic fatty liver disease (NAFLD) after pancreatectomy is a recognized phenomenon; however, its pathophysiology is poorly understood. This study aimed to determine the incidence and identify peri-operative risk factors for the development of de novo NAFLD within various pancreatectomy groups. This single-center retrospective cohort study included patients who underwent pancreatectomy between 2000 and 2020. The incidence rate of de novo NAFLD and time to diagnosis were recorded across patients with malignant versus benign indications for pancreatectomy. The overall incidence of de novo NAFLD after pancreatectomy was 17.5% (24/136). Twenty-one percent (20/94) of patients with malignant indications for surgery …

Monitoring And Modulating Diet And Gut Microbes To Enhance Response And Reduce Toxicity To Cancer Treatment, Anne Knisely, Yongwoo David Seo, Jennifer A Wargo, Manoj Chelvanambi

Faculty, Staff and Student Publications

The gut microbiome comprises a diverse array of microbial species that have been shown to dynamically modulate host immunity both locally and systemically, as well as contribute to tumorigenesis. In this review, we discuss the scientific evidence on the role that gut microbes and diet play in response and toxicity to cancer treatment. We highlight studies across multiple cancer cohorts that have shown an association between particular gut microbiome signatures and an improved response to immune checkpoint blockade, chemotherapy, and adoptive cell therapies, as well as the role of particular microbes in driving treatment-related toxicity and how the microbiome can …

Inhibition Of Colorectal Cancer Tumorigenesis By Ursolic Acid And Doxorubicin Is Mediated By Targeting The Akt Signaling Pathway And Activating The Hippo Signaling Pathway, Dan Hu, Ruo Yu Meng, Thi Van Nguyen, Ok Hee Chai, Byung Hyun Park, Soo Mi Kim

Faculty, Staff and Student Publications

Colorectal cancer (CRC) is one of the deadliest malignant tumors worldwide and its prevalence is increasing in South Korea. The efficacy of combined treatment with natural product‑derived and chemotherapy agents including curcumin combined with 5‑fluorouracil, resveratrol combined with cisplatin and epigallocatechin‑3‑gallate (EGCG) combined with cisplatin in preventing cancer progression and killing cancer cells has emerged. The Akt and Hippo signaling pathways serve a key role in colorectal tumor growth; however, the exact role of the crosstalk between Akt and Hippo signaling pathways in CRC remains poorly elucidated. The combined effect of UA and DOX on the cell proliferation, apoptosis, migration …

A Pilot Study On Cannabidiol (Cbd) And Eccentric Exercise: Impact On Inflammation, Performance, And Pain, Whitley J. Stone, Danilo Tolusso, Guillermo Pacheco, Shea M. Brgoch, Van T. Nguyen

International Journal of Exercise Science

International Journal of Exercise Science 16(2): 109-117, 2023. Cannabidiol (CBD) is a non-psychoactive cannabinoid purported to reduce symptoms of discomfort. Individuals are now using CBD to treat symptoms of multiple sclerosis, seizures, and chronic pain. Animal models indicate that CBD may be effective at reducing inflammation post fatiguing exercise. However, little evidence is available to evaluate these findings in humans. Therefore, the purpose of this investigation was to evaluate the impact of two doses of CBD oil on inflammation (IL-6), performance, and pain after an eccentric loading protocol. Participants (n = 4) participated in three conditions (placebo, low dose, …