Digital Commons Network^™

Void-Semiconductor Gaas Photonic Crystal Surface-Emitting Lasers By Epitaxial Regrowth And Single-Epitaxy Methods, Kevin James Reilly

Nanoscience and Microsystems ETDs

Monolithic semiconductor lasers including edge-emitting lasers (EELs) and vertical-cavity surface-emitting lasers (VCSELs) fail to realize simultaneous achievement of both high-power high-quality beams due to intrinsic limitations of their resonant cavity. Photonic crystal surface emitting lasers (PCSELs) address these structural limitations through employment of a two-dimensional photonic crystal (PC) cavity that creates feedback at a single wavelength for laterally scalable devices. This function of the PC allows PCSELs to power scale with area while maintaining single-mode emission required for diffraction-limited beams. In this way, PCSELs fulfill an industry demand for high-power high-quality lasing from a single chip.

Early PCSELs were fabricated …

On The Effects Of Geometrical And Fluid Conditions On Thermal-Hydraulics Of Miniature Heat Sinks, Mahyar Pourghasemi

Mechanical Engineering ETDs

During the past three years, miniature heat sinks have been integrated into the cooling loop of devices such as MW-class gyrotron resonators and high-power laser arrays. These applications involve high cooling rates in the range of 20-25 MW/m². Liquid metals such as Na and NaK offer very high thermal conductivity in the range of 16-79 W/mK, while their dynamic viscosities are only slightly higher than water viscosity. They can also be used in applications with operating temperatures varying from 25 ^oC to as high as 800 ^oC due to their very high boiling points. Several research …

Cyber-Secure Distributed Control Of Microgrids With Improved Communication And Control Protocols, Jee Won Choi

Mechanical Engineering ETDs

This dissertation proposes a cyber-secure distributed control of microgrids with improved communication and control protocols. The finite-time event-triggered control protocol for islanded AC and DC secondary control is introduced. For AC microgrids, the proposed strategy can effectively perform frequency restoration and voltage regulations while sharing the active and reactive power among the distributed generators (DGs) based on their power ratings. For DC microgrids, the proposed control protocol can provide accurate current sharing and critical bus voltage regulation. The finite-time control enables a system to reach a consensus in a finite period of time enhanced from asymptotic convergence. The event-triggered communication …

Spatial Single-Cell Identification Of Cell Layers Within Mouse Brain Using A Novel Spatially Resolved Transcriptomics Technology, Radha Swaminathan

Biomedical Engineering ETDs

Spatially resolved transcriptomics technologies investigate gene expression in the context of a tissue. While imaging-based technologies enable gene expression quantification at a single-cell level, only two NGS-based technologies are currently capable of single-cell resolution. Both Stereo-seq and Seq-Scope involve two rounds of sequencing: one to sequence the location of spatial barcodes and the other to obtain sequence of cDNA. Thus, the objective of the research study is to develop a technology that can capture transcripts from every cell of a tissue without the need for two rounds of sequencing. To this end, a capture surface or barcoded array (similar to …

The Heart And Soul Of Engagement In The Float Pool Team, Kymberly Dexter

Master's Projects and Capstones

Problem: The assistant nurse manager (ANM) role is considered an entry-level management position and is not intended as a permanent career role. The unintended consequence is that there is a high rate of organizational turnover, making it challenging to build and retain a solid, cohesive, and productive team.

Context: A new manager of a float pool team in a 166-bed community hospital found that with little financial investment, a significant impact is made by holding a safe space for listening to the ANM team and designing education and training around what is most important to frontline managers.

Interventions: A baseline …

Perinatal Exercise Effectiveness To Prevent Offspring High-Altitude Pulmonary Hypertension, Eric Leslie

Health, Exercise, and Sports Sciences ETDs

The effectiveness of perinatal exercise (i.e., exercise by mothers immediately prior to, throughout, and after pregnancy) to attenuate high-altitude pulmonary hypertension and associated health consequences in the offspring exposed to chronic hypoxia in early life was investigated. Four groups were used to compare the effects of perinatal exercise to offspring exposed to low altitude (i.e., normoxic) conditions or simulated 4500 meters of high altitude (i.e., hypoxic) as well as their respective, sedentary controls. Offspring in the hypoxic groups had lower body weights and tail lengths as well as higher hematocrits, right ventricular systolic pressures, and right heart weights. The hypoxic …

In Vitro Anti-Helicobacter Pylori And Antioxidant Activities Of Plants Used In Algerian Traditional Medicine For Gastrointestinal Disorders, Souhila Tabak, Bendif Hamdi, Mohamed Djamel Miara, Luca A. Vitali

Journal of Bioresource Management

It has been recognized that gastric colonization with Helicobacter pylori (H. pylori) induces a risk of developing ulcer disease and gastric cancer. The interest of this research relates for the first time to the study of the Anti-Helicobacter pylori activities of three medicinal plants methanolic extracts, namely Allium sativum, Allium cepa and Foeniculum vulgare. The activity of the methanolic extracts was assessed against two strains of H. pylori (SAN158 and 26659) by the disc diffusion method on Muller Hinton agar. The content of phenolic compounds (TPC) was determined by the Folin-Ciocalteu test and the antioxidant …

Christopher A. Johnson

African American Funeral Programs

Funeral Program for Christopher A. Johnson on Dec. 17, 2022 at Holy Spirit Lutheran Church

Evaluation Of Antibacterial Potential Of Artemisinin Extracts Of Artemisia Annua In Vivo And In Vitro, Arsalan Khan, Akhtar Ali, Imtiaz Ali Shah, Umm-E- Aimen, Waseem Ullah, Imtiaz Khan

Journal of Bioresource Management

To ensure universal health care, the World Health Organization recognized the significance of complementary and alternative medicines (CAM) and recommended the use of natural herbs and plants bearing therapeutic potential and fewer adverse effects. Therefore, Artemisia annua herb was evaluated for its antibacterial potential and therapeutic efficacy against Staphylococcus aureus, Streptococcus and Escherichia coli both in vitro and in vivo. Artemisinin was extracted from Artemisia annua by chemical treatment. Subsequently, the culture sensitivity tests were performed on MHA by disk diffusion method to determine the antibacterial potential of the Artemisinin extracts against the test bacteria (in vitro phase). …

Comparison Of Maize Hybrids For Production Of Quality Fodder And Silage In Faisalabad, Punjab, Pakistan, Ali Hamed, Muhammad Shahid Ibni Zamir, Asif Tanveer, Muhammad Yaseen

Journal of Bioresource Management

Fodder crops have to compete with those of field crops, and the majority of farmers are smallholders in the circumstances of Pakistan. Therefore, this study was planned to search for the best maize hybrid which would serve dual purposes, i.e. for grain production as well as its later usage as fodder and silage. So, seven maize hybrids most commonly grown in the vicinity were selected and compared for their forage production. Maize hybrids were sown on ridges followed by all cultural operations as carried out by farmers. At harvest, plant morphological parameters were measured before ensiling the whole maize plant. …

The Pain Of Helping: Crisis Response Teams Experiences With College Student Suicide, Audra E. Dowling

Graduate Theses, Dissertations, and Capstones

This qualitative multicase study explores the lived experiences of seven higher education professionals who serve or have served on a crisis response team at the time of a college student suicide. It asks the following research question: How has a college student suicide impacted the individual psychological needs (safety, trust, esteem, intimacy, control) of those serving on a crisis response team? Using constructivist self-development theory (McCann & Pearlman, 1990) as a lens, psychological needs have been analyzed as fulfilled needs or distorted needs across two interviews and three journaling prompts to assess the impact on seven participants in this qualitative …

Formation And Interrogation Of A Modeling Excel Database For Sorbent Preconcentrate With Gc/Ms, Lisa Caravello

Chemical and Biological Engineering ETDs

Volatile organic compounds (VOCs) are of great interest and the subject of much research, as they can be used in various applications. Preconcentrating this class of analytes is necessary as they can be elusive with simple sampling techniques. VOCs are often captured using sorbents in thermal desorption tubes as preconcentrates prior to analysis, commonly gas chromatography mass spectroscopy (GCMS). There are gaps in knowledge in behavior of materials used as sorbents i.e., if they will retain an analyte of interest appropriately. In this research I seek to eliminate speculation and unknown variables of analyte and sorbent combinations by creating a …

Inheritance Of 2,4‑Dichlorophenoxyacetic Acid (2,4‑D) Resistance In Amaranthus Palmeri, Chandrima Shyam, Dallas E. Peterson, Amit J. Jhala, Mithila Jugulam

Department of Agronomy and Horticulture: Faculty Publications

In this study, the inheritance of 2,4-D resistance in a multiple herbicide-resistant Palmer amaranth (KCTR) was investigated. Direct and reciprocal crosses were performed using 2,4-D-resistant KCTR and susceptible KSS plants to generate F₁ progenies. 2,4-D dose–response assays were conducted to evaluate the response of progenies from each F₁ family along with KCTR and KSS plants in controlled environmental growth chambers. Additionally, 2,4-D-resistant male and female plants from each of the F₁ families were used in pairwise crosses to generate pseudo-F₂ families. Segregation (resistance or susceptibility) of progenies from the F₂ families in response to a …

Using A Stakeholder-Engaged, Iterative, And Systematic Approach To Adapting Collaborative Decision Skills Training For Implementation In Va Psychosocial Rehabilitation And Recovery Centers, Emily B. H. Treichler, Robert Mercado, David Oakes, Dimitri Perivoliotis, Yuliana Gallegos‑Rodriguez, Elijah Sosa, Erin Cisneros, William D. Spaulding, Eric Granholm, Gregory A. Light, Borsika Rabin5,6

Department of Psychology: Faculty Publications

Background: Adaptation of interventions is inevitable during translation to new populations or settings. Systematic approach to adaptation can ensure that fidelity to core functions of the intervention are preserved while optimizing implementation feasibility and effectiveness for the local context. In this study, we used an iterative, mixed methods, and stakeholder-engaged process to systematically adapt Collaborative Decision Skills Training for Veterans with psychosis currently participating in VA Psychosocial Rehabilitation and Recovery Centers.

Methods: A modified approach to Intervention Mapping (IM-Adapt) guided the adaptation process. An Adaptation Resource Team of five Veterans, two VA clinicians, and four researchers was formed. …

Musikah V’Ḥalil, “Music And The Flute”: The Use Of Jewish Prayer In Flute And Piano Music, Kathryn L. Rudnik

Dissertations, 2020-current

Music has been a part of Jewish life since Biblical times and remains an integral part of the culture. Within Jewish music, instruments have also played an important role historically. The flute has been traced through Judaism back to Biblical times; however, it has lost prominence in modern synagogue and religious services. As Western music has developed into the twenty-first century, composers, both Jewish and Gentile, have been exposed to the music of the Jewish communities, some of whom have utilized it in their own compositions. Compositions based on Jewish prayer melodies have brought up the question of whether the …

Activist, Entrepreneur, Leader: The Influence Of Social Justice Advocacy And Entrepreneurial Orientation On Leader Self-Efficacy, Kathleen Q. Johnson

Dissertations, 2020-current

This quantitative study examined individual entrepreneurial orientation and social justice advocacy as antecedents to leader self-efficacy in the complex and dynamic context of the opioid epidemic. Throughout history, leaders have emerged in response to societal challenges; leadership is not restricted to the boundaries of hierarchical, administrative, bureaucratic organizational frameworks. Complexity leadership theory and its recognition of leadership in complex adaptive systems provides an overarching framing. Five characteristics of individual entrepreneurial orientation were incorporated: risk-taking, innovativeness, perseverance, passion and proactiveness (Santos et al., 2020). Social advocacy activity was measured using the social issues advocacy scale (Nilsson et al., 2011). The dependent …

Identifying Systems Of Support In High Schools For Gender And Sexually Diverse Youth Living In Conservative Communities: A Phenomenological Qualitative Study, Nuriyah Bender

Masters Theses, 2020-current

Within the first few months of 2022 more than 300 anti-LGBTQ+ bills were introduced in states across the country (Human Rights Campaign, 2022). Many of these bills, some of which are now laws, discriminate against transgender students or restrict instruction and materials related to LGBTQ+ topics in schools. Gender and Sexually Diverse (GSD) students often do not feel safe in schools (Kosciw et al., 2020). Using a phenomenological approach, this qualitative study sought to identify the factors that helped GSD students feel the most supported in high schools in order to assist educators with actionable ways they can support students …

Medicinal Bismuth: Bismuth-Organic Frameworks As Pharmaceutically Privileged Compounds, Shaila A. Shetu, Luis M. Sanchez-Palestino, Gildardo Rivera-Sanchez, Debasish Bandyopadhyay

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Chemistry)

Historically organometallic compounds have been used to cure certain diseases with limited applications. Although bismuth belongs to the category of heavy metals, many of its derivatives have found applications in modern drug discovery research, mainly because of its low toxicity and higher bioavailability. Being an eco-friendly mild Lewis acid, compounds having bismuth as a central atom are capable of binding several proteins in humans and other species. Bismuth complexes demonstrated antibacterial potential in syphilis, diarrhea, gastritis, and colitis. Apart from antibacterial activities, bismuth compounds exhibited anticancer, antileishmanial, and some extent of antifungal and other medicinal properties. This article discusses major …

Integrated Multi-Omic Analysis Of Low-Grade Ovarian Serous Carcinoma Collected From Short And Long-Term Survivors, Kwong-Kwok Wong, Nicholas W Bateman, Chun Wai Ng, Yvonne T M Tsang, Charlotte S Sun, Joseph Celestino, Tri V Nguyen, Anais Malpica, R Tyler Hillman, Jianhua Zhang, P Andrew Futreal, Christine Rojas, Kelly A Conrads, Brian L Hood, Clifton L Dalgard, Matthew D Wilkerson, Neil T Phippen, Thomas P Conrads, George L Maxwell, Anil K Sood, David M Gershenson

Faculty, Staff and Student Publications

BACKGROUND: Low-grade serous ovarian cancer (LGSOC) is a rare disease that occurs more frequently in younger women than those with high-grade disease. The current treatment is suboptimal and a better understanding of the molecular pathogenesis of this disease is required. In this study, we compared the proteogenomic analyses of LGSOCs from short- and long-term survivors (defined as < 40 and > 60 months, respectively). Our goal was to identify novel mutations, proteins, and mRNA transcripts that are dysregulated in LGSOC, particularly in short-term survivors.

METHODS: Initially, targeted sequencing of 409 cancer-related genes was performed on 22 LGSOC and 6 serous borderline ovarian tumor samples. …

Research Infrastructure Core Facilities At Research Centers In Minority Institutions: Part I-Research Resources Management, Operation, And Best Practices, Paul B Tchounwou, Mohamad Malouhi, Elizabeth O Ofili, Emma Fernández-Repollet, Daniel F Sarpong, Richard Yanagihara, Renato J Aguilera, Cecilia Ayón, Xiaoxin Chen, Asok Dasmahapatra, Song Gao, Cimona V Hinton, Robert Holt, Vladimir Kolesnichenko, Michael D Powell, Fatima Merchant, Kinfe K Redda, Abiel Roche-Lima, Cecilia M Shikuma, Jacqueline J Stevens, Jose A Torres, Robert T Trotter, James Wachira, Paul Wang, Kristen J Wells, Jason White, Yanyuan Wu

Faculty, Staff and Student Publications

Funded by the National Institutes of Health (NIH), the Research Centers in Minority Institutions (RCMI) Program fosters the development and implementation of innovative research aimed at improving minority health and reducing or eliminating health disparities. Currently, there are 21 RCMI Specialized (U54) Centers that share the same framework, comprising four required core components, namely the Administrative, Research Infrastructure, Investigator Development, and Community Engagement Cores. The Research Infrastructure Core (RIC) is fundamentally important for biomedical and health disparities research as a critical function domain. This paper aims to assess the research resources and services provided and evaluate the best practices in …

Toward An Informal Informed Classrooms: Professional Musicians' Informal Music Learning Experiences, Rachel M. Smith

Masters Theses, 2020-current

Authors have studied informal music learning with different age groups. Lucy Green (2005) studied the topic with adolescents and identified it an intuitive and natural way children learn. Chad West and Radio Cremata (2016) studied informal music learning at the collegiate level, and Martina Vasil (2019) studied secondary music teachers who implemented informal music learning strategies in their teaching practices. Informal music learning in adults is relatively under-explored compared to adolescent and collegiate age groups. Utilizing lenses drawn from John Dewey’s curricular ideas to help students find meaning in learning and motivation as viewed through Self-Determination Theory, I sought to …

Two Studies On Binary Program Stylometry: A White-Box Analysis And A Deep Learning Analysis On Some Crypto Ransomware, Alexander Mitchell

Masters Theses, 2020-current

Computer programmers often leave their individual programming styles in source code. Recent studies show that contrary to a popular belief, many of such programming styles can survive, in controlled environments, code compilation into binary. From the binary programming styles can be effectively retrieved for enhanced binary authorship attribution; such binary authorship attribution is often called binary program stylometry. In this thesis, we first perform a white-box impact analysis of various factors in code compilation on programming styles. For the MS Windows platform, we study the impact of multiple compilers, including gcc, Clang, and MSVC, their optimization levels, symbol stripping, and …

Registered Nurse-Led Annual Wellness Visits In Rural Health Clinics: A Program Evaluation Of A New Role, Tina Switzer

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

The passage of the Patient Portability and Affordable Care Act had a goal of increasing access for preventive care. The Medicare Annual Wellness Visit (AWV) has been a free yearly, comprehensive preventive care opportunity for most Medicare beneficiaries since 2011. Because of the time intensive nature of these visits, the overall national completion rate for them has been low as providers often perceive time and resource constraints. Registered Nurses (RNs) have the skill set to complete these visits with minimal provider involvement. Rural residents often face health care access barriers and outcome disparities, and Rural Health Clinics (RHCs) are a …

Improving Access For Medicare Inpatient Psychiatric Patients: A Health Policy Analysis, Malinda B. Whitfield

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

The Medicare Inpatient Psychiatric Services (IPS) policy, originally developed in the 1960s and without any significant or meaningful updates since the 1980’s, is physician specific, does not reflect the current model of care for psychiatric inpatients, and is restrictive for psychiatric mental health nurse practitioner (PMHNP) practice. The policy is complex, consists of outdated regulations, and results in millions of dollars in compliance costs for Inpatient Psychiatric Facilities (IPFs) annually (NABH, 2019). Although clearly an important part of the inpatient psychiatric services team, PMHNPs are not identified or defined in the policy (Center for Medicare and Medicaid Services [CMS], 2019). …

Developing A Quality Improvement Process: Impacting Patient Outcomes And Achieving Ambulatory Accreditation, Colleen E. Nappi

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

Colon cancer is the second leading cause of cancer deaths in the United States (US) and colonoscopy is the best method for screening and detecting cancer before symptoms are present. A colonoscopies' ability to detect precancerous lesions or identify colorectal cancer (CRC) relies on patients having a high-quality bowel preparation. The US Multi Society Task Force (USMSTF) on colorectal cancer set quality standards for colonoscopy including bowel preparation quality, adenoma detection, and cecal intubation times. As a private gastroenterology practice in Northern Virginia was preparing for re-accreditation with the Accreditation Association for Ambulatory Health Care (AAAHC) it was determined that …

Improving Glycemic Control During The Covid-19 Pandemic: A Quality Improvement Project, Megan Henderson

Doctors of Nursing Practice (DNP) Final Projects, 2020-current

Diabetes is a costly, chronic health condition. The COVID-19 pandemic has significantly impacted the delivery of health care and exacerbated chronic health conditions, such as diabetes. Diabetes is one of the most significant comorbid conditions associated with poor COVID-19 outcomes (Cariou et al., 2020). Control of blood glucose levels during the COVID-19 pandemic has proved challenging to maintain. The purpose of this quality improvement project is to identify gaps in diabetic self-care and then implement a diabetic toolkit to improve self-efficacy of diabetes self-management. According to the American Diabetes Association (2022), self-management of diabetes, education, and support from providers is …

Sequencing An Inserted Concatemer In Caenorhabditis Elegans Strain Hlh-29::Gfp, Simon T. Anderson

Senior Honors Projects, 2020-current

Hairy/Enhancer of Split (HES) proteins and their homologs play vital roles in the development of animals, and in the regulation of cancer and other diseases. HLH-29 is an REF-1 family protein and a Caenorhabditis elegans homolog of human HES proteins. A transgenic animal model has been developed to facilitate analyses of this protein, containing an inserted concatemer of the green fluorescent protein reporter gene, regulated by the hlh-29 promoter, and a mutant rol-6 allele. Though the strain has been used previously, the location and structure of the insertion has been unknown. Sequencing of the whole hlh-29::gfp genome with high-molecular weight …

Life Story Narratives Of Adults With Intellectual Disability And Mental Health Problems: Personal Identity, Quality Of Life And Future Orientation, Hefziba Batya Lifshitz, Ayelet Shahar

The Qualitative Report

The narrative is a functional skill and a means for sharing stories which consist of a single event or events causally related to the individual’s past, present, and future. In this study we aimed to explore the narratives of a voiceless population in society and in research: adults with a dual diagnosis of intellectual disability (ID) and a mental health problem (MHP). Our operative goals were to explore the meaning of their lives as people with a dual diagnosis, their quality of life, and their aspirations for the future. The core questions of the study were: which type of disability …

Comparison Of Arctic Alaska Historical Snow Data With Satellite-Derived Benchmarks And Model Results Using Ilamb Software, Mary Szatkowski

Engineering

Understanding and modeling the permafrost system, hydrologic cycle, energy balance, and biologic systems in the Arctic are dependent, in part, on snow depth and snow distribution. Point-source snow measurements provide ground-truth observations of snow depth and snow water equivalent, although these measurements may be limited in their spatial and temporal distributions. Satellite-derived remote sensing products and gridded model output provide spatial coverage of snow properties, but their applicability is affected by their balance of resolution, computational speed, and accuracy confidence. The goal of this research is to assess the performance of three snow data products derived from remote sensing techniques …

Development Of An Active Vacuum Insulation Panel For Use In Building Applications, Haley D. Nelson

Engineering

Vacuum insulation panels, or VIPs, are among the highest performing forms of building insulation available on the commercial market, with some per inch R-values advertised as 60°F·ft²·hr/(BTU·inch). Though there is strong market demand for high-performing forms of insulation, the adoption of VIPs is hindered by their relatively high costs, uncertain service lifespans, sensitivity to internal pressure changes, susceptibility to thermal bridging along their edges, and other issues. Particularly in building applications, typical VIPs are often passed over in favor of insulation types that can be easily customized on-site, are produced to larger dimensions, and are not as vulnerable to damage …