Digital Commons Network^™

Research On Iterative Calculation And Optimization Methods Of Aero-Engine On-Board Model, Xinghua Luo, Jia Geng, Ming Li, Bei Liu, Lei Wang, Zhiping Song

Journal of System Simulation

Abstract: Aeroengine is a complex and time-varying multivariable thermophysical system. The research on the convergence accuracy and rate of the component-level model is of great significance to the model-based engine health management, performance and fault-tolerant control. The existing engine component-level models are generally based on the traditional quasi-Newton method to solve the equilibrium equations simultaneously. Compared with the traditional Newton-Raphson method (N-R method), the convergence speed is optimized, but it is difficult to meet accuracy and real-time requirements of the dynamic model airborne applications within the full envelope. An adaptive variable step factor quasi-Newton method is proposed, which can reduce …

Reliability Parameter Optimization Complex System Simulation Based On R-Vikor Method, Zhiguang Wang, Baiting Liu, Xiaolei Wang, Tao Liu, Zhaowei Yang

Journal of System Simulation

Abstract: The operation of complex simulation system is not isolated, and always affected by multiple external factors and its own performance. In simulation reliability calculation, parameters need to be chosen, and different performance indexes need to be taken into account when comparing with the reference model. The research is transformed into the multi-attribute decision. An system simulation trusted parameter optimization method based on R-VIKOR(resist rank reversal of visekriterijumska optimizacija | kompromisno resenje) is proposed. Multiple sets of aerodynamic parameters of the new model are obtained through model migration theory, and similarity calculation is carried out with the optimal parameters of …

Development Of Tool To Measure Mechanics Of Cylindrical Soft Tissue Samples, Perry Brody

Mechanical Engineering and Materials Science Independent Study

The objective of this study was to develop a tool to measure the mechanics of cylindrical soft tissue samples, specifically applied to the mouse uterus. Specialized equipment is required to perform such testing at the desired scale and sensitivity. An adjustable fixture was developed to mount mouse uterine ring samples with a method that allowed us to perform tensile testing using the ElectroForce 3200 Mechanical Testing System. The geometric parameters of the sample were determined by front and side-angled cameras throughout the test. Using the collected force-displacement data from the ElectroForce and the video recordings, the mechanical response of tissue …

The Negative Effects Of Arbitration Clauses In Meal Delivery Service Subscriptions, Amanda Pasternak

Cardozo Journal of Conflict Resolution (CJCR) Blog

This past June, Daily Harvest, a vegan meal delivery service that sells soups, smoothies, and more recalled one of its products, French Lentil + Leek Crumbles, after hundreds of consumer reports of gastrointestinal illness, potential liver function issues, and other adverse reactions. According to the Food and Drug Administration (FDA), from April 28 to June 17, 2022, around 28,000 units of the recalled product were distributed to consumers throughout the United States via online sales, direct delivery, and retail sales. Samples were also given to a small number of consumers. Daily Harvest received around 470 reports of illness, which the …

Sis-Based Modeling And Simulation Analysis On Exercise Benefit Perception Transmission, Lei Wang, Jinhai Sun, Tuojian Li

Journal of System Simulation

Abstract: In order to distinguish the relationship between individual health behavior change and collective health behavior emergence, deal with the challenges of mathematical description of typical health information dissemination processes in social networks and social experiments, SIS(susceptible-infected-susceptible)model is introduced to simulate the dissemination process of classical health information exercise effect perception to meet the requirements of social system complexity, individual diversity and intelligence. To carry out numerical experiments on the propagation process of exercise effect perception to identify the phase change process of the collective health behavior emergence, agent-based modeling and simulation are utilized through NetLogo. Experimental results show …

Implementing Dei In Aviation Education: Coping And Addressing Mental Health Concerns, Jorge L. D. Albelo Ph.D., Michael F. O'Toole Ph.D., Samantha Bowyer

Publications

In recent years, different global events have led to increased awareness of the benefits of promoting diversity, equity, and inclusion in the workplace and education. Notably, the aviation industry is seeing increased research initiatives to promote DEI among all generations. Nevertheless, given the rising concerns about mental health in higher education, this paper sought to connect coping and addressing mental health through implementing DEI teachings in aviation education. Integrating DEI in the aviation classroom can be challenging, as many faculty members might feel uncomfortable addressing the topic in their courses. Consequently, the researchers proposed and tested an aviation education approach …

Matter Of Ruotolo V. State Of New York Div. Of Hous. & Community Renewal

All Decisions

Court affirms DHCR decision to dismiss landlord's Article 78 petition to deregulate a unit and evict tenant, and claim for money damages against DHCR. Landlord petitioner has received the exact relief sought, as they have obtained possession and the apartment is now deregulated. The Supreme Court has no jurisdiction over petitioner's claim for money damages, Court of Claims does.

Activation Of Basal Forebrain-To-Lateral Habenula Circuitry Drives Reflexive Aversion And Suppresses Feeding Behavior, Jessica L Swanson, Joshua Ortiz-Guzman, Snigdha Srivastava, Pey-Shyuan Chin, Sean W Dooling, Elizabeth Hanson Moss, Mikhail Y Kochukov, Patrick J Hunt, Jay M Patel, Brandon T Pekarek, Qingchun Tong, Benjamin R Arenkiel

Faculty, Staff and Student Publications

Environmental cues and internal states such as mood, reward, or aversion directly influence feeding behaviors beyond homeostatic necessity. The hypothalamus has been extensively investigated for its role in homeostatic feeding. However, many of the neural circuits that drive more complex, non-homeostatic feeding that integrate valence and sensory cues (such as taste and smell) remain unknown. Here, we describe a basal forebrain (BF)-to-lateral habenula (LHb) circuit that directly modulates non-homeostatic feeding behavior. Using viral-mediated circuit mapping, we identified a population of glutamatergic neurons within the BF that project to the LHb, which responds to diverse sensory cues, including aversive and food-related …

Tennessee Annual Comprehensive Financial Report For The Fiscal Year Ended June 30, 2022, Tennessee. Department Of Finance & Administration.

Annual Comprehensive Financial Reports

No abstract provided.

Spaci: Deciphering Spatial Cellular Communications Through Adaptive Graph Model, Ziyang Tang, Tonglin Zhang, Baijian Yang Ph.D., Jing Su, Qianqian Song

Publications

Cell-cell communications are vital for biological signalling and play important roles in complex diseases. Recent advances in single-cell spatial transcriptomics (SCST) technologies allow examining the spatial cell communication landscapes and hold the promise for disentangling the complex ligand-receptor (L-R) interactions across cells. However, due to frequent dropout events and noisy signals in SCST data, it is challenging and lack of effective and tailored methods to accurately infer cellular communications. Herein, to decipher the cell-to-cell communications from SCST profiles, we propose a novel adaptive graph model with attention mechanisms named spaCI. spaCI incorporates both spatial locations and gene expression profiles of …

Physical Model Of Cilia Motion, Toby Utterback

Mechanical Engineering and Materials Science Independent Study

The motion of cilia could be further understood by creating and analysing a large scale model with similar stiffness and property values. Varying amounts of vibrating HEXBUG robots, representing motion and active particles, were placed in series with different segment lengths connecting them. The oscillating motion of a ciliium was able to be replicated and analyzed using autotracing and autotracking programs. The amplitude of the model increased with increasing length, while increasing length had an inconclusive effect on period. Furthermore, the visual path of a marked end segment repeated with each oscillation recorded.

Influence Of Reading Habit On Perception And Use Of Reference Sources By Postgraduate Students In The Faculty Of Education Of Ibadan, Nigeria, Sunday A. Oluwaniyi, Lawrence Akingbade

Library Philosophy and Practice (e-journal)

Abstract

Libraries play a critical role in promoting reading habits. If postgraduate students cultivate the habits of reading, their perception and use of reference sources will be enhanced. The main objective is to determine the influence of reading habits on the perception and use of reference sources by postgraduates in the Faculty of Education, University of Ibadan. Descriptive survey research design was adopted for the study and the study population consisted of 2503 postgraduate students of the Faculty of Education, University of Ibadan, Nigeria, Stratified random sampling technique was used to select the sample size of 337 and tie questionnaire …

Knowing The Biosphere: Documentation, Specimens, Archives, And Names Reveal Environmental Change And Emerging Pathogens, Eric P. Hoberg, Valeria Trivellone, Joseph A. Cook, Jonathan L. Dunnum, Walter A. Boeger, Daniel R. Brooks, Salvatore J. Agosta, Jocelyn P. Colella

MANTER: Journal of Parasite Biodiversity

One Health programs and trajectories are now the apparent standard for exploring the occurrence and distribution of emerging pathogens and disease. By definition, One Health has been characterized as a broadly inclusive, collaborative, and transdisciplinary approach with connectivity across local to global scales, which integrates the medical and veterinary community to recognize health outcomes emerging at the environmental nexus for people, animals, plants, and their shared landscapes. One Health has been an incomplete model, conceptually and operationally, focused on reactive and response-based foundations, to limit the impact of emerging pathogens and emerging infectious diseases and, as such, lacks a powerful …

Medical Racism: Comparing Prenatal Care Across Races In The United States, Rubina Cheema

Student Research

Prenatal care describes any care a woman receives during her pregnancy. It is intended to keep both the mother and the child healthy and also to reduce the risk of complications during and after birth. This care is especially important for women with high-risk factors so that doctors and nurses are able to monitor their health and the health of their baby during the duration of their pregnancy. For prenatal care to be most effective, it is imperative to begin prenatal care within the first trimester of a woman's pregnancy. However, in the United States, medical racism creates a major …

2022 Holidays In New Hampshire Wrapup: More Travel, More Stress, Fake Christmas Trees 12/21/2022, Unh Survey Center

All UNH Survey Center Polls

Most New Hampshire residents plan to travel or host for the December holidays this year, up significantly since 2020. Artificial Christmas trees remain more popular than real trees among Granite Staters, and one in five will not have any tree this year. One in five report high levels of stress related to the holidays, up slightly since last year. Christmas Vacation, It's a Wonderful Life, and Die Hard are mentioned most often by Granite Staters as their favorite holiday movie.

Implementation Of The Family Help Protocol: A Feasibility Project For A West Texas Icu, Rebecca Mcclay

Dissertations

The purpose of this project was to determine if there is sufficient bedside ICU nurse buy-in to the Family HELP protocol to make implementation feasible at one county hospital in West Texas.

Living Tree Doctrines Of The Canadian Constitution And Indigenous Law, Emma C. Howes

Dalhousie Journal of Legal Studies

The living tree doctrine of the Canadian Constitution uses the metaphor of a tree to present the Constitution as a dynamic organism which can evolve over time to accommodate new influences. This essay examines the history of this doctrine along with its possible Indigenous counterparts. In this examination, both the arboreal imagery of such doctrines and their dynamic approach to law are considered. The essay explores the benefits and disadvantages of employing a living tree approach to accommodate Indigenous legal traditions within the Canadian formal legal system.

Gatekeeping Admissions: Access To Justice And Inclusive Admissions Processes, Sarah Kriekle

Dalhousie Journal of Legal Studies

Law schools are the gatekeepers to the legal profession, and there are multiple social barriers that impact access to a legal education across a proportionally diverse range of people. This article will first rely on existing literature to demonstrate why diversity in the legal profession is an access to justice issue and to illustrate the current homogeneity that exists within the profession. This article will then argue that two primary factors prevent law schools from attracting a more diverse student body. The first factor is the over-reliance on numerical statistics like grade point average (GPA) and Law School Admissions Test …

Mental Age V Chronological Age: Rethinking Our Approach To Criminal Responsibility For Developmentally Delayed Young Persons Under The Youth Criminal Justice Act, Michael Michel

Dalhousie Journal of Legal Studies

The Youth Criminal Justice Act (YCJA) is meant to ensure that only the most serious cases warrant imprisonment. Both in the pre- and post-trial stages of a criminal proceeding, the YCJA contains safeguards designed to divert youth away from correctional institutions and encourage the use of community-based services. Yet, for youth suffering from mental disorders or injuries that cause significant cognitive impairment, these safeguards can be inadequate, detrimental, or simply unavailable. To resolve this shortcoming, this article advocates using mental age, rather than chronological age, as the benchmark for determining criminal responsibility under the YCJA.

Weakly-Supervised Learning Method For The Recognition Of Potato Leaf Diseases, Junde Chen, Xiaofang Deng, Yuxin Wen, Weirong Chen, Adnan Zeb, Defu Zhang

Engineering Faculty Articles and Research

As a crucial food crop, potatoes are highly consumed worldwide, while they are also susceptible to being infected by diverse diseases. Early detection and diagnosis can prevent the epidemic of plant diseases and raise crop yields. To this end, this study proposed a weakly-supervised learning approach for the identification of potato plant diseases. The foundation network was applied with the lightweight MobileNet V2, and to enhance the learning ability for minute lesion features, we modified the existing MobileNet-V2 architecture using the fine-tuning approach conducted by transfer learning. Then, the atrous convolution along with the SPP module was embedded into the …

The U.S. Supreme Court And Democratic Backsliding, Thomas Keck

Political Science - All Scholarship

This paper assesses the performance of the Supreme Court as democratic guardrail during five prior periods of democratic crisis in the United States. It finds that most such periods witnessed efforts by the governing regime to entrench themselves in power, and that the Court has rarely provided an effective check on such democratic abuses. Rather than serving as a reliable democratic guardrail, the Court has regularly exercised what Dixon and Landau call “weak-form abusive judicial review”; that is, it has declined to check attacks on democracy emerging from other centers of power. On one occasion, the Court has undermined democracy …

Machine Learning And Protein Allostery, Sian Xiao, Gennady M. Verkhivker, Peng Tao

Mathematics, Physics, and Computer Science Faculty Articles and Research

The fundamental biological importance and complexity of allosterically regulated proteins stem from their central role in signal transduction and cellular processes. Recently, machine-learning approaches have been developed and actively deployed to facilitate theoretical and experimental studies of protein dynamics and allosteric mechanisms. In this review, we survey recent developments in applications of machine-learning methods for studies of allosteric mechanisms, prediction of allosteric effects and allostery-related physicochemical properties, and allosteric protein engineering. We also review the applications of machine-learning strategies for characterization of allosteric mechanisms and drug design targeting SARS-CoV-2. Continuous development and task-specific adaptation of machine-learning methods for protein allosteric …

Factors Influencing Young Consumers’ Impulse Intentions Toward Visiting Pop-Up Stores In South Africa, Miriam-Miri Retief, Bertha Jacobs, Ann-Marie Fiore

Journal of Marketing and Consumer Behaviour in Emerging Markets

Consumers are constantly seeking out new and memorable experiences. This study empirically examines how external factors, such as the characteristics of innovation (relative advantage, trialability, observability, low complexity, compatibility) and exterior store design, and internal factors (positive mood, hedonic motivations, consumer innovativeness) aff ect young consumers’ impulse intention toward visiting pop-up stores in the South African context. Survey data was collected from a convenient sample of 461 students from two universities in South Africa via a self-administered questionnaire. Multiple regression analysis revealed that (a) external factors related to the characteristics of innovation (i.e., compatibility and low complexity), (b) exterior store …

Four Students Receive Grants For Ideas Through Titan New Venture Challenge, Mj Soria

News and Events (Discontinued Series)

No abstract provided.

Creating And Sustaining Democratic Spaces In Education, Joanna Haynes, Judith Suissa

Plymouth Institute of Education

This article explores the context for the accompanying suite of papers on creating and sustaining democratic spaces in education. Prompted by the centenary of Summerhill, the internationally famous democratic school founded in Suffolk, England, in 1921, by A.S. Neill, this collection of papers explores and broadens out the central questions at the heart of experiments in democratic education. We suggest that, at a time of distrust in and questioning of the central institutions of democratic government, and in the wake of challenges to the mainstream system of state schooling, these questions are more relevant than ever. We argue that detailed …

Molecular Markers In Maternal Blood Exosomes Allow Early Detection Of Fetal Alcohol Spectrum Disorders, Nune Darbinian, Armine Darbinyan, John Sinard, Gabriel Tatevosian, Nana Merabova, Faith D'Amico, Tarek Khader, Ahsun Bajwa, Diana Martirosyan, Alina K Gawlinski, Richa Pursnani, Huaqing Zhao, Shohreh Amini, Mary Morrison, Laura Goetzl, Michael E Selzer

Faculty, Staff and Student Publications

Prenatal alcohol exposure can cause developmental abnormalities (fetal alcohol spectrum disorders; FASD), including small eyes, face and brain, and neurobehavioral deficits. These cannot be detected early in pregnancy with available imaging techniques. Early diagnosis could facilitate development of therapeutic interventions. Banked human fetal brains and eyes at 9−22 weeks’ gestation were paired with maternal blood samples, analyzed for morphometry, protein, and RNA expression, and apoptotic signaling. Alcohol (EtOH)-exposed (maternal self-report) fetuses were compared with unexposed controls matched for fetal age, sex, and maternal race. Fetal brain-derived exosomes (FB-E) were isolated from maternal blood and analyzed for protein, RNA, and apoptotic …

Dissecting The Recruitment And Self-Organization Of Αsma-Positive Fibroblasts In The Foreign Body Response, Maria Parlani, Matthew L Bedell, Antonios G Mikos, Peter Friedl, Eleonora Dondossola

Faculty, Staff and Student Publications

The foreign body response (FBR) is a clinically relevant issue that can cause malfunction of implanted medical devices by fibrotic encapsulation. Whereas inflammatory aspects of the FBR have been established, underlying fibroblast-dependent mechanisms remain unclear. We here combine multiphoton microscopy with ad hoc reporter mice expressing α-smooth muscle actin (αSMA) protein to determine the locoregional fibroblast dynamics, activation, and fibrotic encapsulation of polymeric materials. Fibroblasts invaded as individual cells and established a multicellular network, which transited to a two-compartment fibrotic response displaying an αSMA cold external capsule and a long-lasting, inner αSMA hot environment. The recruitment of fibroblasts and extent …

Systemic Delivery Of Divalent Europium From Ligand Screening With Implications To Direct Imaging Of Hypoxia, Md Mamunur Rashid, Brooke A Corbin, Pavan Jella, Caitlyn J Ortiz, Md Abul Hassan Samee, Robia G Pautler, Matthew J Allen

Faculty, Staff and Students Publications

Hypoxia is a hallmark of many diseases, including cancer, arthritis, heart and kidney diseases, and diabetes, and it is often associated with disease aggressiveness and poor prognosis. Consequently, there is a critical need for imaging hypoxia in a noninvasive and direct way to diagnose, stage, and monitor the treatment and development of new therapies for these diseases. Eu-containing contrast agents for magnetic resonance imaging have demonstrated potential for in vivo imaging of hypoxia via changes in metal oxidation state from +2 to +3, but rapid oxidation in blood limits EuII-containing complexes to only studies compatible with direct injection to sites. …

Concurrent Mutations In Sf3b1 And Phf6 In Myeloid Neoplasms, Zhuang Zuo, L Jeffrey Medeiros, Sofia Garces, Mark J Routbort, Chi Young Ok, Sanam Loghavi, Rashmi Kanagal-Shamanna, Fatima Zahra Jelloul, Guillermo Garcia-Manero, Kelly S Chien, Keyur P Patel, Rajyalakshmi Luthra, C Cameron Yin

Faculty, Staff and Student Publications

It has been reported that gene mutations in SF3B1 and PHF6 are mutually exclusive. However, this observation has never been rigorously assessed. We report the clinicopathologic and molecular genetic features of 21 cases of myeloid neoplasms with double mutations in SF3B1 and PHF6, including 9 (43%) with myelodysplastic syndrome, 5 (24%) with acute myeloid leukemia, 4 (19%) with myeloproliferative neoplasms, and 3 (14%) with myelodysplastic/myeloproliferative neoplasms. Multilineage dysplasia with ring sideroblasts, increased blasts, and myelofibrosis are common morphologic findings. All cases but one had diploid or non-complex karyotypes. SF3B1 mutations were detected in the first analysis of all the …

Ototoxicity Of Topical Antibiotic Ear Drops In Chronic Suppurative Otitis Media In Humans: A Review Of The Literature, Syed Zohaib Maroof Hussain, Syed S Hashmi, Asad Qayyum

Faculty, Staff and Student Publications

An electronic search of the literature was performed for reported cases of ototoxicity associated with the use of topical antibiotic ear drops in humans. The dosage, duration, and type of ototoxic preparations involved were recorded. Due to the scant quantity of low-quality information that is currently available, there was uncertainty about the usefulness of topical antibiotics in enhancing the resolution of ear discharge in patients with chronic suppurative otitis media. However, despite this uncertainty, there are some data to show that using topical antibiotics in comparison to a placebo or in conjunction with a systemic antibiotic may be useful. Additionally, …