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A Spectrophotometric Determination Of Barium Complexation With Methylthymol Blue, Wesley Alexander

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In this work, a spectrophotometric titration of methylthymol blue (MTB) with barium chloride was performed at pH = 7.5, 9.6, and 12.2 to determine the stoichiometry of complexation between the two as well as formation constants and absorptivity coefficients. Complexes of 1:1, 2:1, and 3:1 Ba:MTB were suggested by the experimental data upon fitting with appropriate models using Beer’s Law. The molar absorptivities of free MTB species at 605 nm were determined to be ����2������4− = 5.0 (± 0.2) x 103 L·mol-1·cm-1, ����������5− = 7.3 (± 0.3) x 103 L·mol-1·cm-1, ��������6− = 1.3 (± 0.2) x 104 L·mol-1·cm-1. At pH …

Modeling Als-Associated Matrin-3 Toxicity In Yeast, Widad El-Zein

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ALS is a neurodegenerative disease characterized by degeneration of upper and lower motor neurons in the brain and spinal cord leading to progressive paralysis and ultimately death. Perturbations in RNA metabolism and RNA binding proteins have emerged as underlying defects in ALS pathogenesis. Matrin-3 is a multifunctional RNA binding protein that has been linked to familial and sporadic ALS. Matrin-3 is normally found in the nucleus, but mutations in the gene cause mislocalization of the protein from the nucleus into the cytoplasm of neuronal cells where it forms protein aggregates. In this study, we show that over-expressing human MATR3 in …

Estimation Of The Amount Of Active Pharmaceutical Ingredient In Over-The-Counter Available Aspirin Formulations Using Titrimetry, Uv-Visible Spectrophotometry And Raman Spectroscopy, Harismranjeet K. Chahal

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Counterfeit pharmaceuticals are a serious threat to public safety worldwide. Adverse health effects including resistance to treatment and death have resulted from the consumption of such medicines. Aspirin, which is a non-steroidal anti-inflammatory drug, has been counterfeited in the past due to its increasing demand. Rapid and easy analytical methods are needed to detect these counterfeit medicines and put a halt to the growing number of such incidents. In this study, quantitative estimation of active pharmaceutical ingredient (API) content in different over-the-counter available aspirin tablets was done using titrimetry and UV- Visible spectrophotometry. Qualitative analysis was done using Raman spectroscopy. …

The Role Of Pi4kb In Cellular Localization Of Small Gtpases, Parisa Sadrpour

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Constitutively active oncogenic mutant K-Ras is one the principal contributors to human cancers including 90% of pancreatic, 50% of colorectal and 32% of non-small cell lung cancers. However, except for K-Ras G12C oncogenic mutant, which only presents in about 13% of non-small cell lung cancer patients, there is no anti-K-Ras therapy for a considerable subset of K-Ras mutations in human tumors, reflecting challenges for targeting oncogenic K-Ras activity. K-Ras is a membrane-bound small GTPase; when active, it triggers multiple signaling pathways regulating a variety of key cellular functions such as cell growth, proliferation and survival. To initiate these signaling cascades, …

Reconstruction Of Gut Microbiome Via Intermittent Feeding, Kourtney Sprague

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The benefits of intermittent fasting have been studied across many facets of health. It is known that physiologically fasting results in a metabolic switch from liver-derived glucose to adipose cell derived ketones to be used as energy and signaling molecules. Fasting down-regulates inflammation, increases expression of antioxidant defenses, and activates pathways for DNA repair and autophagy. While fasting or intermittent feeding effects on host physiology have been identified, the relationship between fasting and gut microbiome is not as well known. In times of gut rest, resident microbes undergo detoxication and motility, and in times of activity, gut microbes undergo DNA …

Shenandoah Valley Partnership: Growing And Enhancing The Food And Beverage Manufacturing Industry, Justin Williams

Master of Urban and Regional Planning Capstone Projects

This plan analyzes how the Shenandoah Valley Partnership can grow and enhance its food and beverage manufacturing industry. To answer this question, I interviewed and surveyed food and beverage manufacturers to understand their business needs, as well as interviewed service providers to identify their relationships with this industry. The four main results from the plan were:

• There is a need for more capital for the businesses.

• There is a labor shortage in the industry.

• The Shenandoah Valley has an excellent distribution location.

• The industry has a poor relationship with the region’s service providers.

The plan outlines recommendations on how institutions …

Northern Neck Economic Development Plan: Improving Connectivity Within The Food Industry, Annie Weidhaas

Master of Urban and Regional Planning Capstone Projects

The Northern Neck region seeks a better understanding of its food industry and how the industry contributes to economic growth and development. This plan examines the food industry in the Northern Neck to identify existing assets and missing linkages that can improve regional economic development.

The Northern Neck faces challenges to its regional economic growth and development. This plan uses a rural and regional perspective and interviews with local food-related businesses and stakeholders to answer the following research questions: 1) What is currently happening within the region’s food industry? 2) Can connectivity within the region’s food industry improve? And 3) …

Rejuvenate: North Church Street Corridor Plan, Robert J. Tate

Master of Urban and Regional Planning Capstone Projects

The city of Burlington is facing a waning issue to stimulate economic growth in neighborhoods in its eastern portion. The Rejuvenate: North Church Street Corridor Plan strives to use equitable development and smart growth strategies to uplift the economic prosperity of the North Church Street corridor. This plan recommends improving pedestrian infrastructure, fostering sustainable development growth patterns, beautifying streetscapes, and increasing social and civic capital. The recommendations proposed collectively work towards re-imagining the American suburban landscape into walkable mixed-use communities.

The Reconstructing Randolph Project, Latoya Gray-Sparks

Master of Urban and Regional Planning Capstone Projects

The Reconstructing Randolph Project is an in-depth historical case study of one of the last thriving and intact Black neighborhoods in Richmond to be disrupted by urban renewal. The case study utilizes a Black geographical lens, historic preservation practices and counter cartography to illuminate the rich history and people who made up the Randolph neighborhood. The plan also outlines policies and strategies that can be implemented to 1) amplify and preserve the history of Randolph and (2) protect long-term Black residents who wish to remain in a city that is quickly changing due to gentrification.

Richmond Community Compost Initiative Plan, Brendan Mcdowell

Master of Urban and Regional Planning Capstone Projects

The City of Richmond is beginning the process of creating a composting program for the first time in the city’s history. It is part of a cross-departmental collaborative plan to divert food waste from the landfill and into a new composting program. The Office of sustainability is in the process of drafting the RVAGreen 2050 Climate and Equity Master Plan for Richmond, which includes an ambitious zero-waste goal. In order to accomplish this future goal, the city must begin setting up the infrastructure to begin diverting waste from the landfill.

The purpose of the Community Composting Initiative Plan is to …

Revitalization Strategies For Downtown Elkton, Virginia, Gabrielle Dean

Master of Urban and Regional Planning Capstone Projects

Elkton is a rural Virginia town eager to revitalize its downtown. After years of decline, there is a newfound interest in developing the downtown commercial district. This plan addresses community goals and current market conditions to provide implementable recommendations for revitalization in a rural context. The recommendations are modeled after the Main Street America Community Transformation strategy and primarily focus on vacant property abatement and utilizing urban design tactics to create a walkable district.

Williamsburg Road Commercial Corridor Revitalization Plan, Rachael B. Thayer

Master of Urban and Regional Planning Capstone Projects

Sandston is the second oldest established neighborhood in the County of Henrico, and the commercial corridor found along Williamsburg Road has served this community for over a century. This corridor developed during a time when Williamsburg Road, or Route 60, was the primary roadway between the City of Richmond and Williamsburg. As seen with other American corridors that emerged before the Federal-Aid Highway Act of 1956, the Sandston corridor has experienced a halt in the economic development and decrease in the vitality of the economic base in recent decades. The Williamsburg Road Commercial Corridor Revitalization Plan strives to identify key …

A New Normal: How Covid-19 And Digital Contact Tracing Highlight A Need For New Fourth Amendment Norms, Danielle J. Fong

Emory Law Journal

Contact tracing helps epidemiologists identify individuals who have been exposed to a virus. Manual contact tracing has been used for decades to interrupt the transmission of disease and reduce the number of infections within a population. It is a pillar of disease control. But the manual process has certain limitations—it is time-intensive, expensive, and subject to human error. Digital contact tracing overcomes these limitations. Using GPS and Bluetooth technologies, digital contact tracing applications automate and expedite the tracing and notification processes, with life-saving implications. In 2020, countries that implemented contact tracing technology in response to COVID-19 contained outbreaks, minimized incidence …

Having Your Cake And Eating It Too: Why Voluntary Post-Petition 401(K) Contributions Are Disposable Income, Austin S. Howell

Emory Bankruptcy Developments Journal

Following the 2005 amendments to the Bankruptcy Code, the majority of chapter 13 debtors have been successful in minimizing their repayment obligations to creditors while bolstering their financial stability during retirement. The Bankruptcy Code allows chapter 13 debtors to retain their assets and repay their debts to creditors using their earned income. Alternatively, debtors may simply avoid some of the liability by dedicating a portion of their earned income for reasonably necessary expenses. Judicial inconsistencies have emerged concerning whether voluntary post-petition 401(k) retirement contributions for chapter 13 debtors constitute disposable income in accordance with Sections 541(b)(7) and 1325(b) of the …

The "Ideal Debtor" And The "Traditional" American Household, A. Mechele Dickerson

Emory Bankruptcy Developments Journal

Laws that award governmental benefits reflect an archetype of the type of person deemed worthy of governmental assistance and generally favor and reward people who have specific personal attributes or who engage in activities deemed socially desirable. Just as the Bankruptcy Code favors the “Ideal Debtor,” state and federal laws favor and subsidize Americans who live in a “traditional household.” Historically, this household consisted of husbands who earned income in the paid labor market and wives who stayed home to provide unpaid care for their husbands and minor children. Households that deviated from that norm rarely received the full range …

The Hardship Discharge And How It Can Improve Debtor Success, Abbie Schmadeke

Emory Bankruptcy Developments Journal

Chapter 13 bankruptcy has long been heralded as a moral alternative to chapter 7 liquidations. Despite this, success among chapter 13 debtors is limited, and debtors who opt for this route face other challenges. The hardship discharge allows chapter 13 debtors to receive a discharge of their debts without plan completion. While the provision has been a piece of the bankruptcy law for nearly a century, little research on its effects on debtors exists. The struggles that chapter 13 debtors face underlies the need for more research on the hardship discharge as a potential solution. This Comment seeks to utilize …

Membranoproliferative Glomerulonephritis With Monoclonal Igg Deposits, Jennifer Lamar, Leela Kantamneni, Farrah Ibrahim

UAB Huntsville Research Day - All Presentations

2022 oral presentation

Case Presentation: Abdominal Pain, Caitlyn Tomblin, Jesse Faulk

UAB Huntsville Research Day - All Presentations

2022 oral presentation

Manly Man Nearly Kicks The Can: Testosterone Supplementation Induced Polycythemia In Acute Cva, Jesse Zheng, Alan Baggett

UAB Huntsville Research Day - All Presentations

2022 oral presentation

Microrna Correlates Of Childhood Maltreatment And Suicidality, Clinton Martin, Janaki Nimmagadda, Anupama Yedla, Richard Shelton, Yogesh Dwivedi, Matthew Bonds

UAB Huntsville Research Day - All Presentations

2022 research poster

Evaluating Clinical Outcomes Of Tranexemic Acid Administration In Cranial Vault Reconstruction For Craniosynostosis, P White, E Soto, A R. Clark, J Lepard, J Johnston, K Niedermeier, C J. Rozelle, J H. Grant, R P. Myers

UAB Huntsville Research Day - All Presentations

2022 research poster

Evaluating Microsurgical Pedicle Lengthening In Free Tissue Transfer, A Review Of The Literature, Anthony Wilson, Edgar Soto, Sharon D. Lawson, Ali Kilic, René P. Myers, Jorge I. De La Torre

UAB Huntsville Research Day - All Presentations

2022 research poster

An Unusual Presentation Of Alpha-1 Antitrypsin Deficiency, Khalid Ameen, Anthony Wilson, Farrah Ibrahim

UAB Huntsville Research Day - All Presentations

2022 clinical vignette poster

Infected Native Aortic Valve Aneurysm In A Patient With Streptococcus Viridans Infective Endocarditis, Khalid Ameen, Maha Al-Baghdadi, John Fanning

UAB Huntsville Research Day - All Presentations

2022 clinical vignette poster

A Case Of Postural Orthostatic Tachycardia Syndrome And Anxiety, Nadia Anabtawi, Clinton Martin, Janaki Nimmagadda, Richard Shelton

UAB Huntsville Research Day - All Presentations

2022 clinical vignette poster

A Rare Case Of Hemophagocytic Lymphohistiocytosis (Hlh), Lauren Beggs, Dyan Alvarez Dupaya, Farrah Ibrahim, Katie Glosemeyer

UAB Huntsville Research Day - All Presentations

2022 clinical vignette poster

A Case Of Hepatocellular Carcinoma (Hcc) Presenting With Peritoneal Metastasis (Pm), Rafik Elbeblawy, Christopher Terrell, Farrah Ibrahim, Ali Hachem

UAB Huntsville Research Day - All Presentations

2022 clinical vignette poster

Human Immunodeficiency Virus (Hiv) Infection Presenting With Progressive Rash, Rafik Elbeblawy, Christopher Terrell, Nate Moore, Ali Hassoun

UAB Huntsville Research Day - All Presentations

2022 clinical vignette poster

When Surgery Tips The Patient Over … (Postoperative Hepatic Encephalopathy In A Cirrhotic Patient With Tips), Rafik Elbeblawy, Oseyime Okoeguale, Jimmy Molyneux, Roger Smalligan

UAB Huntsville Research Day - All Presentations

2022 clinical vignette poster

Treating An Adult Likea Child: A Rare Inflammatory Myofibroblastic Tumor, Kyle Hornbuckle, Marc Zelickson

UAB Huntsville Research Day - All Presentations

2022 clinical vignette poster