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Articles 73411 - 73440 of 73789
Full-Text Articles in Entire DC Network
Investigating Signs Of Orbital Decay In The Tres-1 Exoplanetary System, Amanda F. Wester
Investigating Signs Of Orbital Decay In The Tres-1 Exoplanetary System, Amanda F. Wester
Honors Theses and Capstones
Transit observations of exoplanetary systems can be used to investigate orbital decay. TrES-1b is an exoplanet hypothesized to be experiencing orbital decay due to observed transit timing variations (TTVs) [12]. Numerous transits must be observed to establish a long term pattern to conclusively determine if the planet’s orbit is decaying. Measurements were made using the UNH Observatory where 2 transits were observed of the TrES-1b transiting system on February 27, 2022 and March 5, 2022. A CCD camera was used to image the transit and capture calibration images. The software AstroImageJ (AIJ) was used to calibrate the images and perform …
Introduction: Special Issue On Racial Capitalism And Law, Carmen G. Gonzalez, Athena D. Mutua
Introduction: Special Issue On Racial Capitalism And Law, Carmen G. Gonzalez, Athena D. Mutua
Journal Articles
No abstract provided.
Rethinking Economics For Tax Law And Political Economy, Martha T. Mccluskey
Rethinking Economics For Tax Law And Political Economy, Martha T. Mccluskey
Journal Articles
No abstract provided.
Perspectives On Determinism In Quantum Mechanics: Born, Bohm, And The 'Quantal Newtonian' Laws, Viraht Sahni
Perspectives On Determinism In Quantum Mechanics: Born, Bohm, And The 'Quantal Newtonian' Laws, Viraht Sahni
Publications and Research
Quantum mechanics has a deterministic Schrödinger equation for the wave function. The Göttingen-Copenhagen statistical interpretation is based on the Born Rule that interprets the wave function as a ‘probability amplitude’. A precept of this interpretation is the lack of determinism in quantum mechanics. The Bohm interpretation is that the wave function is a source of a field experienced by the electrons, thereby attributing determinism to quantum theory. In this paper we present a new perspective on such determinism. The ideas are based on the equations of motion or ‘Quantal Newtonian’ Laws obeyed by each electron. These Laws, derived from the …
Extractable Entanglement From A Euclidean Hourglass, Takanori Anegawa, Norihiro Iizuka, Daniel Kabat
Extractable Entanglement From A Euclidean Hourglass, Takanori Anegawa, Norihiro Iizuka, Daniel Kabat
Publications and Research
We previously proposed that entanglement across a planar surface can be obtained from the partition function on a Euclidean hourglass geometry. Here we extend the prescription to spherical entangling surfaces in conformal field theory. We use the prescription to evaluate log terms in the entropy of a conformal field theory in two dimensions, a conformally coupled scalar in four dimensions, and a Maxwell field in four dimensions. For Maxwell we reproduce the extractable entropy obtained by Soni and Trivedi. We take this as evidence that the hourglass prescription provides a Euclidean technique for evaluating extractable entropy in quantum field theory.
John Copeland Nagle: A Man For All Seasons, Patricia A. O'Hara
John Copeland Nagle: A Man For All Seasons, Patricia A. O'Hara
Journal Articles
Many fine law schools have faculty members who are outstanding teachers, preeminent scholars, and generous colleagues. Few law schools are as blessed as we were at Notre Dame to have someone as singular as John Copeland Nagle—a person who was all those things professionally, but who was also a man without self-serving ego or guile; a man possessed of a moral compass that made him "true north" to so many of us; a person who consistently acted out of charity in an effort to do the right thing in all things.
John was genuine, authentic, self-giving, and humble with every …
Coming Full Circle On Human Rights In The Global Economy: International Economic Law Tools To Realize The Right To Development, Diane A. Desierto
Coming Full Circle On Human Rights In The Global Economy: International Economic Law Tools To Realize The Right To Development, Diane A. Desierto
Journal Articles
From the Article
This article argues that the discipline and profession of international economic law has undergone a significant architectural change to focus on human rights law as both the premise and promise of the international economic system. Contrary to prevailing currents that focus on the irrelevance of the global economic system to realize human rights, this article argues that international economic law tools have already been converging within the last decade to authentically realize the Right to Development of individuals, groups, and populations. The Draft Convention on the Right to Development defines the right as the enjoyment, participation, and …
Landslide Inventory Dataset Post Hurricane Stan (2005), Lake Atitlan Region, Guatemala, Elia Axinia Machado, Yuri Gorokhovich, Mahta Ghahremani
Landslide Inventory Dataset Post Hurricane Stan (2005), Lake Atitlan Region, Guatemala, Elia Axinia Machado, Yuri Gorokhovich, Mahta Ghahremani
Publications and Research
Landslides are a global hazard of devastating impacts resulting in thousands of fatalities every year, substantial economic losses, and long-term economic disruption. Examining the frequency and distribution of landslides is important to better understand their associated factors and to identify where future landslides may occur. The dataset described in this article consists of landslides digitized as polygons using high resolution aerial photography collected after Hurricane Stan (October 2005), which caused severe damages in Central America. In Guatemala, the total economic impact of Hurricane Stan has been estimated at US$983 Million dollars, with 719,000 ha of land lost due to flooding, …
Quark And Gluon Entanglement In The Proton On The Light Cone At Intermediate X, Adrian Dumitru, Eric Kolbusz
Quark And Gluon Entanglement In The Proton On The Light Cone At Intermediate X, Adrian Dumitru, Eric Kolbusz
Publications and Research
In QCD with $N_c$ colors the antisymmetric valence quark color space singlet state $\sim \epsilon_{i_1\cdots i_{N_c}} |i_1,\cdots, i_{N_c}\rangle$ of the proton corresponds to the reduced density matrix $\rho_{ij}=(1/N_c) \delta_{ij}$ for a single color degree of freedom. Its degenerate spectrum of eigenvalues, $\lambda_i=1/N_c$, the purity $\tr \rho^2 = 1/N_c$, and the von Neumann entropy $S_\mathrm{vN}=\log(N_c)$ all indicate maximal entanglement of color. On the other hand, for $N_c\to\infty$ the spatial wave function of the proton factorizes into valence quark wave functions determined by a mean field [E. Witten, Nucl. Phys. B160, 57 (1979)] where there is no entanglement of spatial degrees of …
A Framework For Near-Real Time Monitoring Of Diversity Patterns Based On Indirect Remote Sensing, With An Application In The Brazilian Atlantic Rainforest, Andrea Paz, Thiago S. Silva, Ana C. Carnaval
A Framework For Near-Real Time Monitoring Of Diversity Patterns Based On Indirect Remote Sensing, With An Application In The Brazilian Atlantic Rainforest, Andrea Paz, Thiago S. Silva, Ana C. Carnaval
Publications and Research
Monitoring biodiversity change is key to effective conservation policy. While it is difficult to establish in situ biodiversity monitoring programs at broad geographical scales, remote sensing advances allow for near-real time Earth observations that may help with this goal. We combine periodical and freely available remote sensing information describing temperature and precipitation with curated biological information from several groups of animals and plants in the Brazilian Atlantic rainforest to design an indirect remote sensing framework that monitors potential loss and gain of biodiversity in near-real time. Using data from biological collections and information from repeated field inventories, we demonstrate that …
Bft2: A General Class Of 2d N = (0, 2) Theories, 3-Manifolds And Toric Geometry, Sebastían Franco, Xingyang Yu
Bft2: A General Class Of 2d N = (0, 2) Theories, 3-Manifolds And Toric Geometry, Sebastían Franco, Xingyang Yu
Publications and Research
We introduce and initiate the study of a general class of 2d N = (0, 2) quiver gauge theories, defined in terms of certain 2-dimensional CW complexes on oriented 3- manifolds. We refer to this class of theories as BFT2’s. They are natural generalizations of Brane Brick Models, which capture the gauge theories on D1-branes probing toric Calabi-Yau 4-folds. The dynamics and triality of the gauge theories translate into simple transformations of the underlying CW complexes. We introduce various combinatorial tools for analyzing these theories and investigate their connections to toric Calabi-Yau manifolds, which arise as their …
Magnetoexcitons In Phosphorene Monolayers, Bilayers, And Van Der Waals Heterostructures, Roman Ya. Kezerashvili, Anastasia Spiridonova, Andrew Dublin
Magnetoexcitons In Phosphorene Monolayers, Bilayers, And Van Der Waals Heterostructures, Roman Ya. Kezerashvili, Anastasia Spiridonova, Andrew Dublin
Publications and Research
We study direct and indirect excitons in Rydberg states in phosphorene monolayers, bilayers, and van der Waals (vdW) heterostructure in an external magnetic field within the framework of the effective-mass approximation. The magnetic field is applied perpendicular to the monolayer or heterostructure and is varied between 0 and 60 T. Binding energies of magnetoexcitons are calculated by numerical integration of the Schrödinger equation using the Rytova-Keldysh potential for direct magnetoexcitons and both the Rytova-Keldysh and Coulomb potentials for indirect magnetoexcitons. The latter aids in the understanding of the role of screening in phosphorene. We report the magnetic field energy contribution …
Fano 3-Folds, Reflexive Polytopes And Brane Brick Models, Sebastían Franco, Rak-Kyeong Seong
Fano 3-Folds, Reflexive Polytopes And Brane Brick Models, Sebastían Franco, Rak-Kyeong Seong
Publications and Research
Reflexive polytopes in n dimensions have attracted much attention both in mathematics and theoretical physics due to their connection to Fano n-folds and mirror symmetry. This work focuses on the 18 regular reflexive polytopes corresponding to smooth Fano 3-folds. For the first time, we show that all 18 regular reflexive polytopes have corresponding 2d (0, 2) gauge theories realized by brane brick models. These 2d gauge theories can be considered as the worldvolume theories of D1-branes probing the toric Calabi-Yau 4-singularities whose toric diagrams are given by the associated regular reflexive polytopes. The generators of the mesonic moduli …
Characterizing Changes In Extreme Ozone Levels Under 2050s Climate Conditions: An Extreme-Value Analysis In California, Bradley Wilson, Mariah Pope, Jeremy R. Porter, Edward Kearns, Evelyn Shu, Mark Bauer, Neil Freeman, Mike Amodeo, David Melecio-Vazquez, Ho Hsieh, Maggie Tarasovitch
Characterizing Changes In Extreme Ozone Levels Under 2050s Climate Conditions: An Extreme-Value Analysis In California, Bradley Wilson, Mariah Pope, Jeremy R. Porter, Edward Kearns, Evelyn Shu, Mark Bauer, Neil Freeman, Mike Amodeo, David Melecio-Vazquez, Ho Hsieh, Maggie Tarasovitch
Publications and Research
Ground-level ozone has a well established climate penalty associated with changing meteorological conditions under future climate change, but most existing research focuses exclusively on ozone-temperature relationships defined at specific locations. Using an extreme-value theory approach, we model relationships between temperature, humidity, and vapor pressure deficit and maximum daily 8 h ozone concentrations (MDA8) across California using a combination of ozone station network data and Community Multiscale Air Quality Modeling System (CMAQ) model output from 2008 to 2017. We use a spatial regression with time varying bias coefficients to fuse station observations and modeled output into a spatially explicit gridded ozone …
The Octagon At Large M, Riccardo Argurio, Matteo Bertolini, Sebastían Franco, Eduardo García-Valdecasas, Shani Meynet, Antoine Pasternak, Valdo Tatitscheff
The Octagon At Large M, Riccardo Argurio, Matteo Bertolini, Sebastían Franco, Eduardo García-Valdecasas, Shani Meynet, Antoine Pasternak, Valdo Tatitscheff
Publications and Research
Recently, the first instance of a model of D-branes at Calabi-Yau singularities where supersymmetry is broken dynamically into stable vacua has been proposed. This construction was based on a system of N regular and M = 1 fractional branes placed at the tip of the so-called (orientifolded) Octagon singularity. In this paper we show that this model admits a large M generalization, having the same low energy effective dynamics. This opens up the possibility that the effect on geometry is smooth, and amenable to describing the gauge theory all along the RG flow, including the deep IR, in terms of …
A Horor Theory For Introspective Consciousness, Adriana Renero, Richard Brown
A Horor Theory For Introspective Consciousness, Adriana Renero, Richard Brown
Publications and Research
Higher-order theories of consciousness typically account for introspection in terms of one’s higher-order thoughts being conscious, which would require a third-order thought—i.e., a thought about a thought about a mental state. In this work, we offer an alternative account of introspection that builds on the recent Higher-Order Representation of a Representation (HOROR) theory of phenomenal consciousness. According to HOROR theory, phenomenal consciousness consists in having the right kind of higher-order representation. We claim that this theory can be extended to introspection by recognizing that there is a distinctive kind of consciousness—i.e., introspective consciousness—which can be accounted for as the theory …
Non-Physician’S Challenges In Sexual And Reproductive Health Care Provision For Women Of Reproductive Age With Cancer: A Scoping Review Of Barriers And Facilitators, Qi Chen, Emma Carpenter, Kari White
Non-Physician’S Challenges In Sexual And Reproductive Health Care Provision For Women Of Reproductive Age With Cancer: A Scoping Review Of Barriers And Facilitators, Qi Chen, Emma Carpenter, Kari White
Publications and Research
Purpose: The American Society of Clinical Oncology Clinical Practice guidelines recommend that non-physicians such as nurses, social workers, psychologists should be prepared to discuss fertility and sexual concerns with patients. However, literature showed that the utilization rate of sexual and reproductive care for women with cancer remained low. We conducted a scoping review to describe non-physicians’ roles, barriers and facilitators providing sexual and reproductive health (SRH) care to women of reproductive age with cancer.
Methods: We searched six databases for articles that met the following criteria: 1) English-language; 2) original research; 3) non-physician providers; 4) women with cancer under …
The Indian Mission Of The Institute Of Blessed Virgin Mary (Ibvm) Nuns: Convents, Curriculum, And Indian Women, Nilanjana Paul
The Indian Mission Of The Institute Of Blessed Virgin Mary (Ibvm) Nuns: Convents, Curriculum, And Indian Women, Nilanjana Paul
History Faculty Publications
This study focuses on the Indian mission of IBVM nuns, and the role played by them in the spread of female education in India. While acknowledging that missionaries were part of the imperial process, this study analyzes the work of Catholic nuns in India, their convents, and curriculum to show how their work advanced women’s educational opportunities in India. In the process the study examines how Catholic nuns resisted the dominating attitude of the Catholic Church in India. The last section of the article examines how Christian influence under missionaries not only prepared good mothers and wives but also trained …
Harnessing The Power Of Interdisciplinary Research With Psychology-Informed Cyberbullying Detection Models, Deborah Hall, Yasin N. Silva, Brittany Wheeler, Lu Cheng, Katie Baumel
Harnessing The Power Of Interdisciplinary Research With Psychology-Informed Cyberbullying Detection Models, Deborah Hall, Yasin N. Silva, Brittany Wheeler, Lu Cheng, Katie Baumel
Computer Science: Faculty Publications and Other Works
Cyberbullying has become increasingly prevalent, particularly on social media. There has also been a steady rise in cyberbullying research across a range of disciplines. Much of the empirical work from computer science has focused on developing machine learning models for cyberbullying detection. Whereas machine learning cyberbullying detection models can be improved by drawing on psychological theories and perspectives, there is also tremendous potential for machine learning models to contribute to a better understanding of psychological aspects of cyberbullying. In this paper, we discuss how machine learning models can yield novel insights about the nature and defining characteristics of cyberbullying and …
Magi1 Inhibits Interferon Signaling To Promote Influenza A Infection, Yin Wang, Jun-Ichi Abe, Khanh M Chau, Yongxing Wang, Hang Thi Vu, Loka Reddy Velatooru, Fahad Gulraiz, Masaki Imanishi, Venkata S K Samanthapudi, Minh T H Nguyen, Kyung Ae Ko, Ling-Ling Lee, Tamlyn N Thomas, Elizabeth A Olmsted-Davis, Sivareddy Kotla, Keigi Fujiwara, John P Cooke, Di Zhao, Scott E Evans, Nhat-Tu Le
Magi1 Inhibits Interferon Signaling To Promote Influenza A Infection, Yin Wang, Jun-Ichi Abe, Khanh M Chau, Yongxing Wang, Hang Thi Vu, Loka Reddy Velatooru, Fahad Gulraiz, Masaki Imanishi, Venkata S K Samanthapudi, Minh T H Nguyen, Kyung Ae Ko, Ling-Ling Lee, Tamlyn N Thomas, Elizabeth A Olmsted-Davis, Sivareddy Kotla, Keigi Fujiwara, John P Cooke, Di Zhao, Scott E Evans, Nhat-Tu Le
Faculty, Staff and Student Publications
We have shown that membrane-associated guanylate kinase with inverted domain structure-1 (MAGI1), a scaffold protein with six PSD95/DiscLarge/ZO-1 (PDZ) domains, is involved in the regulation of endothelial cell (EC) activation and atherogenesis in mice. In addition to causing acute respiratory disease, influenza A virus (IAV) infection plays an important role in atherogenesis and triggers acute coronary syndromes and fatal myocardial infarction. Therefore, the aim of this study is to investigate the function and regulation of MAGI1 in IAV-induced EC activation. Whereas, EC infection by IAV increases MAGI1 expression, MAGI1 depletion suppresses IAV infection, suggesting that the induction of MAGI1 may …
The Potential Of Biology-Guided Radiation Therapy In Thoracic Cancer: A Preliminary Treatment Planning Study, Steven N Seyedin, Rostem Bassalow, Osama R Mawlawi, Lehendrick M Turner, Roshal R Patel, Samuel R Mazin, Oluwaseyi M Oderinde, Yevgen Voronenko, Cody A Wages, Peter D Olcott, Joe Y Chang, Peter A Balter, James W Welsh
The Potential Of Biology-Guided Radiation Therapy In Thoracic Cancer: A Preliminary Treatment Planning Study, Steven N Seyedin, Rostem Bassalow, Osama R Mawlawi, Lehendrick M Turner, Roshal R Patel, Samuel R Mazin, Oluwaseyi M Oderinde, Yevgen Voronenko, Cody A Wages, Peter D Olcott, Joe Y Chang, Peter A Balter, James W Welsh
Faculty, Staff and Student Publications
PURPOSE: We investigated the feasibility of biology-guided radiotherapy (BgRT), a technique that utilizes real-time positron emission imaging to minimize tumor motion uncertainties, to spare nearby organs at risk.
METHODS: Volumetric modulated arc therapy (VMAT), intensity-modulated proton (IMPT) therapy, and BgRT plans were created for a paratracheal node recurrence (case 1; 60 Gy in 10 fractions) and a primary peripheral left upper lobe adenocarcinoma (case 2; 50 Gy in four fractions).
RESULTS: For case 1, BgRT produced lower bronchus V40 values compared to VMAT and IMPT. For case 2, total lung V20 was lower in the BgRT case compared to VMAT …
Development Of A Piezo-Mechanical Battery, Caleb Aba-Onukaogu Aba-Onukaogu
Development Of A Piezo-Mechanical Battery, Caleb Aba-Onukaogu Aba-Onukaogu
Theses and Dissertations
The piezo-mechanical battery is designed to store energy in a flat spiral spring and harvest the kinetic energy of the unwinding spring using piezoelectric unimorph cantilever beams. The system, initially proposed on a micro scale, was designed to function on a macro scale. The power spring of the system was designed to deliver enough torque to run the system and provide enough force to the escapement mechanism to excite the cantilever beams. The gear system is designed as a compound epicyclic gear system with a gear ratio of 55:1. The cantilever beams were designed to act as springs as well …
Role Of Aurora Kinase A, Rab4a, And Endolysosomes In The Development Of Alzheimer’S Disease-Like Pathology, Zahra Afghah
Role Of Aurora Kinase A, Rab4a, And Endolysosomes In The Development Of Alzheimer’S Disease-Like Pathology, Zahra Afghah
Theses and Dissertations
Endosomes and lysosomes (endolysosomes) are organelles that play key roles in cell survival and cell death. These acidic intracellular organelles are the principal sites for intracellular hydrolytic activity required for the maintenance of cellular homeostasis. Endolysosomes are involved in the degradation of plasma membrane components, extracellular macromolecules, as well as intracellular macromolecules and cellular fragments. Understanding the physiological significance and pathological relevance of endolysosomes is now complicated by relatively recent findings of physical and functional interactions between endolysosomes and other intracellular organelles including endoplasmic reticulum, mitochondria, plasma membranes, and peroxisomes. Indeed, evidence clearly indicates that endolysosome dysfunction and inter-organellar signaling …
The Experience Of Saudi Students Writing Academic English In Sex-Separated Classrooms, Rana Alsaadi
The Experience Of Saudi Students Writing Academic English In Sex-Separated Classrooms, Rana Alsaadi
Theses and Dissertations
This is a qualitative research that investigates the experiences of undergraduate Saudi female and male students majoring in English at Taif University, Saudi Arabia. These students were part of different sections of a course that teaches academic English writing and research in an English as a Foreign Language context. These Saudi female and male students draw on their perceptions of three main points; First, how they experienced the academic English writing course in sex-separated classrooms. Second, how the current sex-separated classrooms influence their learning of English and how if this hypothetically change to mixed-sex classrooms their experiences in learning English …
Energy Harvesting & Wing Morphing Design Using Piezoelectric Macro Fiber Composites, Md Saifuddin Ahmed Atique
Energy Harvesting & Wing Morphing Design Using Piezoelectric Macro Fiber Composites, Md Saifuddin Ahmed Atique
Theses and Dissertations
Energy harvesting from vibration sources was a very promising field of research throughout the last few decades among the engineers and scientist as considering the necessity of renewable/green energy for the welfare of mankind. Unused vibration energy exists in the surrounding or machineries was always tried to be utilized. Since then, by using piezoelectric transduction, researchers started to harvest the vibration energy. However, after the invention of piezo ceramics Macro Fiber Composites (MFC) by NASA, the research in this field augmented a lot due to its high efficiency to convert mechanical strain or vibration to useful electrical power and vice …
Traditional And Technology-Enhanced Learning: Faculty Perspectives And Student Experiences And Satisfaction In An Art & Design Program During The Covid-19 Pandemic, Cynthia Margaret Boehm
Traditional And Technology-Enhanced Learning: Faculty Perspectives And Student Experiences And Satisfaction In An Art & Design Program During The Covid-19 Pandemic, Cynthia Margaret Boehm
Theses and Dissertations
Digital skills are essential in today’s digital age, which means that students require technology-enhanced skills in higher education to succeed in their future careers. In this study, faculty and students in an Art & Design (A&D) program at a Midwestern university were surveyed regarding their perspectives and experiences. During the COVID-19 pandemic, this university changed its teaching and learning strategy by offering courses online during the Fall 2020 and Spring 2021 semesters, where quarantine was mandatory. Still, the A&D program did not provide all courses online. This study included online surveys based on three constructs of quality of studio learning, …
Real-Time Machine Learning Models To Detect Cyber And Physical Anomalies In Power Systems, Zakaria El Mrabet
Real-Time Machine Learning Models To Detect Cyber And Physical Anomalies In Power Systems, Zakaria El Mrabet
Theses and Dissertations
A Smart Grid is a cyber-physical system (CPS) that tightly integrates computation and networking with physical processes to provide reliable two-way communication between electricity companies and customers. However, the grid availability and integrity are constantly threatened by both physical faults and cyber-attacks which may have a detrimental socio-economic impact. The frequency of the faults and attacks is increasing every year due to the extreme weather events and strong reliance on the open internet architecture that is vulnerable to cyber-attacks. In May 2021, for instance, Colonial Pipeline, one of the largest pipeline operators in the U.S., transports refined gasoline and jet …
A Novel Numerical Model For Transient Mixed-Flow Analysis In Pipe And Conduit Systems, David B. Khani
A Novel Numerical Model For Transient Mixed-Flow Analysis In Pipe And Conduit Systems, David B. Khani
Theses and Dissertations
While responding to a wet weather flow event, stormwater pipe systems experience complex transient flow in which both open channel and pressurized flow regimes may coexist. The resulting transient flows may induce significant positive and negative pressure surges that can be intense enough to compromise the integrity of the system such as pipe rupture or flooding the streets and damage to properties. Unfortunately, available off-the-shelf software such as InfoWorks, Mike Urban, etc. are not comprehensive enough to capture all features of the resulting transient flows. When the elastic feature of the flow system becomes of significant importance, these models fail …
Efficient Distance Accuracy Estimation Of Real-World Environments In Virtual Reality Head-Mounted Displays, Fatima Kuehn
Efficient Distance Accuracy Estimation Of Real-World Environments In Virtual Reality Head-Mounted Displays, Fatima Kuehn
Theses and Dissertations
Virtual reality (VR) is a very promising technology with many compelling industrial applications. As many advancements have been made recently to deploy and use VR technology in virtual environments, they are still less mature to be used to render real environments. The current VR systems settings, which are developed for virtual environments rendering, fail to adequately address the challenges of capturing and displaying real-world virtual reality that these systems entail. Before these systems can be used in real life settings, their performance needs to be investigated, more specifically, depth perception and how distances to objects in the rendered scenes are …
The Architecture And Dynamics Of Gene Regulatory Networks Directing Cell-Fate Choice During Murine Hematopoiesis, Joanna Handzlik
The Architecture And Dynamics Of Gene Regulatory Networks Directing Cell-Fate Choice During Murine Hematopoiesis, Joanna Handzlik
Theses and Dissertations
Mammals produce hundreds of billions of new blood cells every day througha process known as hematopoiesis. Hematopoiesis starts with stem cells that develop into all the different types of cells found in blood by changing their genome-wide gene expression. The remodeling of genome-wide gene expression can be primarily attributed to a special class of proteins called transcription factors (TFs) that can activate or repress other genes, including genes encoding TFs. TFs and their targets therefore form recurrent networks called gene regulatory networks (GRNs). GRNs are crucial during physiological developmental processes, such as hematopoiesis, while abnormalities in the regulatory interactions of …