Digital Commons Network^™

Approved Courses 12-6-22, Angela Brock

Individual Course Committee (ICC)

No abstract provided.

Isolation And Characterization Of Chi-Like Salmonella Bacteriophages Infecting Two Salmonella Enterica Serovars, Typhimurium And Enteritidis, Addisu D. Teklemariam, Mona G. Alharbi, Rashad R. Al-Hindi, Ibrahim Alotibi, Abdullah A. Aljaddawi, Sheren A. Azhari, Ahmed Esmael

Nebraska Center for Virology: Faculty Publications

Salmonella enterica Serovar Typhimurium and Salmonella enterica Serovar Enteritidis are well-known pathogens that cause foodborne diseases in humans. The emergence of antibiotic-resistant Salmonella serovars has caused serious public health problems worldwide. In this study, two lysogenic phages, STP11 and SEP13, were isolated from a wastewater treatment plant in Jeddah, KSA. Transmission electron microscopic images revealed that both phages are new members of the genus “Chivirus” within the family Siphoviridae. Both STP11 and SEP13 had a lysis time of 90 min with burst sizes of 176 and 170 PFU/cell, respectively. The two phages were thermostable (0 ^◦C …

Use Of Modeling To Support Students’ Learning Of Energy Concepts, Delaney Carone, Ashley Perkins

Honors Theses

This paper presents a method for teaching energy concepts to children to children. By implementing modeling and the predict-observe-explain method, teachers can greatly improve critical thinking skills and abstract conception capacity in young students. The main focus of this lesson is based on the disciplinary core idea of Energy, and specifically on 4-PS3-1: Use evidence to construct an explanation relating the speed of an object to the energy of that object (NGSS Lead States, 2012). Aligned with the Next Generation Science Standard 4.PS3.1, the lesson gives examples of activities and tips on how teachers can teach students to explain how …

Unh Announces Winners Of 10th Annual N.H. Social Venture Innovation Challenge, Erika Mantz

Media Relations

No abstract provided.

Enhancing The Wettability Of Polyetheretherketone (Peek) Membrane With Ozone For Improving Fuel Cell Performance, Hunter Heineman, Omran Omar, Benjamin Rippel, Ryan Keeley, Michael Mehan, Surendra K. Gupta, Gerald A. Takacs

Articles

Ozone was reacted with the aromatic membrane polyetheretherketone (PEEK) to form oxidized functional groups on the surface to enhance the attraction and transport of protons in fuel cells. Ozonation of unsaturated C-C sp2 bonds in PEEK formed a primary ozonide which dissociated to primarily produce O=C-O/O=C-OH moieties, and the root mean squared roughness factor (Rq) decreased from 7.4 nm, for the untreated sample, down to 3.1 nm. The oxidation of the surface and decrease in surface roughness made the surface increase in hydrophilicity as observed by the decrease in the water contact angle (CA) from 80.3° for untreated PEEK down …

Tumor-Infiltrating Lymphocytes For Adoptive Cell Therapy, Amod A. Sarnaik, Shari Pilon-Thomas, Mark Mclaughlin, Hao Liu

USF Patents

Disclosed are compositions and methods for ex vivo expansion of tumor-infiltrating lymphocytes for use in adoptive cell therapy (ACT). Also disclosed are compositions and method for identifying an agent for ex vivo expansion of tumor-infiltrating lymphocytes for use in ACT. Also disclosed are methods for treating cancer using tumor-infiltrating lymphocytes expanded by the disclosed methods.

Assessing Broad-Scale Stony Coral Tissue Loss Disease Intervention Activities In Southeast Florida, Usa, Kathryn Toth

All HCAS Student Capstones, Theses, and Dissertations

Reef-building corals are crucial to the long-term existence of Caribbean coral reef ecosystems, providing both direct and indirect, local and global, ecological, economic, and social benefits. Stony coral tissue loss disease (SCTLD) is endemic in southeast Florida first appearing in 2014 and present in 2022. Effective in situ disease intervention treatments using antibiotic paste stop disease progression ~ 90% of the time. Between May 2019 and April 2022, 1,037 corals, >85% of which were Montastraea cavernosa, were treated during disease intervention dives in southeast Florida. This study investigated intervention activities over three years in an effort to make them more …

Ten Considerations For Solar-Powered Irrigation In Utah, Ngonidzashe Mufute, Matt Yost, Burdette Barker, Kalen Taylor, Mark Nelson, Randall Violett, Jody Gale

All Current Publications

This fact sheet outlines considerations for using solar-powered irrigation in Utah:

• Solar powered irrigation (SPI) is becoming more cost effective and practical to consider on the farm as the cost of alternative sources of energy are rising.
• Irrigators can now benefit from incentives such as tax credits to help offset costs.
• Investing in solar provides more independence from price fluctuations and energy shortages.
• Considerations for SPI systems include energy demand of the irrigation system, type and value of crops grown, available incentives and support, cost and accessibility of alternative energy sources, and multiple uses of the …

Approved Programs 12-6-22, Angela Brock

Programs Committee (PC)

No abstract provided.

December 6, 2022, The Dakota Student

The Dakota Student

No abstract provided.

Construction And Case Study Of A Novel Lung Cancer Risk Index, Ali Faghani, Lei Guo, Mahdi Vaezi, Margaret Wright Geise, M. Courtney Hughes

Faculty Articles, Papers, and Other Scholarship

Purpose

This study constructs a lung cancer risk index (LCRI) that incorporates many modifiable risk factors using an easily reproducible and adaptable method that relies on publicly available data.

Methods

We used meta-analysis followed by Analytic Hierarchy Process (AHP) to generate a lung cancer risk index (LCRI) that incorporates seven modifiable risk factors (active smoking, indoor air pollution, occupational exposure, alcohol consumption, secondhand smoke exposure, outdoor air pollution, and radon exposure) for lung cancer. Using county-level population data, we then performed a case study in which we tailored the LCRI for use in the state of Illinois (LCRIIL).

Results

For …

Independent - Dec. 6, 2022, Monty Stites

The Independent (1988-present)

No abstract provided.

Ucc Minutes 12-6-22, Angela Brock

UCC Agendas/Minutes

No abstract provided.

Understanding Cnc Capacity Through Production Time Estimation, Kaitlin Bluhm

Honors Theses

Landscape Forms is a high-end outdoor furniture company. This thesis was completed at the Landscape Forms woodshop located in Kalamazoo, MI. Landscape Forms initially reached out regarding their CNC machines being the bottleneck and it was determined that the current product standards and capacity of the CNC machines at Landscape Forms were not accurate. This causes issues when planning and scheduling their incoming orders. During this thesis, two tools were developed over the course of two semesters. The first tool helped to create accurate product standards for their CNC machines depending on the different product types and second, a CNC …

Industry 4.0, Zachary Zeitler

Honors Theses

The ultimate goal of this project is to automate quality control processes on various machines which include 3D printers, welders, routers, CNCs, and more. Using the “Digital Twin” approach, we want to automate monitoring, data collection, data analysis, and corrective action. Our involvement begins with building a new piece of software that can perform two specific functions and collect data from cameras. We are not attempting to analyze the data, make corrective action, or design a final version of the physical attributes. Our software provides the user with the ability to capture an image set or a 3D scan and …

A High-Accuracy Detection System: Based On Transfer Learning For Apical Lesions On Periapical Radiograph, Yueh Chuo, Wen-Ming Lin, Tsung-Yi Chen, Mei-Ling Chan, Yu-Sung Chang, Yan-Ru Lin, Yuan-Jin Lin, Yu-Han Shao, Chiung-An Chen, Patricia Angela R. Abu

Department of Information Systems & Computer Science Faculty Publications

Apical Lesions, one of the most common oral diseases, can be effectively detected in daily dental examinations by a periapical radiograph (PA). In the current popular endodontic treatment, most dentists spend a lot of time manually marking the lesion area. In order to reduce the burden on dentists, this paper proposes a convolutional neural network (CNN)-based regional analysis model for spical lesions for periapical radiographs. In this study, the database was provided by dentists with more than three years of practical experience, meeting the criteria for clinical practical application. The contributions of this work are (1) an advanced adaptive threshold …

The Double Silence: Reflections On Music And Musicians, Antoni Pizà

Publications and Research

A translation of EL DOBLE SILENCI, published in Catalan in 2003. The book is a compilation of essays originally published in Diario de Mallorca (2000-2003).

The Challenge Of Space, Susan Dumais

UNH Today Archive

No abstract provided.

Ai And The Regulatory Paradigm Shift At The Fda, Catherine M. Sharkey, Kevin M. K. Fodouop

Duke Law Journal Online

No abstract provided.

Open-Source Benchmarking Of Ibd Segment Detection Methods For Biobank-Scale Cohorts, Degui Zhi

Faculty, Staff and Student Publications

In the recent biobank era of genetics, the problem of identical-by-descent (IBD) segment detection received renewed interest, as IBD segments in large cohorts offer unprecedented opportunities in the study of population and genealogical history, as well as genetic association of long haplotypes. While a new generation of efficient methods for IBD segment detection becomes available, direct comparison of these methods is difficult: existing benchmarks were often evaluated in different datasets, with some not openly accessible; methods benchmarked were run under suboptimal parameters; and benchmark performance metrics were not defined consistently. Here, we developed a comprehensive and completely open-source evaluation of …

Remote Reef Cryptobenthic Diversity: Integrating Autonomous Reef Monitoring Structures And In Situ Environmental Parameters, M Steyaert, M Lindhart, A Khrizman, Rb Dunbar, Mb Bonsall, Da Mucciarone, E Ransome, N Santodomingo, P Winslade, Cei Head

School of Biological and Marine Sciences

Coral reef sessile organisms inhabiting cryptic spaces and cavities of the reef matrix perform vital and varied functional roles but are often understudied in comparison to those on exposed surfaces. Here, we assess the composition of cryptobenthic taxa from three remote tropical reef sites (Central Indian Ocean) alongside a suite of in situ environmental parameters to determine if, or how, significant patterns of diversity are shaped by local abiotic factors. To achieve this, we carried out a point-count analysis of autonomous reef monitoring structure (ARMS) plate images and employed in situ instrumentation to recover long-term (12 months) profiles of flow …

Mechanical Engineering News, Georgia Southern University

Mechanical Engineering: News & Publications (2013-2023)

• Graduate Students Present Combustion Research

Clove Essential Oil And Nanoclays-Based Active Food Packaging, Kalpani Y. Perera, Shubham Sharma, Amit K. Jaiswal, Swarna Jaiswal

Articles

Active food packaging materials enhance the shelf-life of food products while reducing food waste. The current study aims to develop a biodegradable active food packaging material. The food packaging material was developed with the incorporation of clove essential oil, sodium alginate, gelatin, and nanoclay films were prepared. The influences of nanoclay and clove on the surface, optical, mechanical, chemical, barrier, and pH-indicating properties were studied. The lightness and yellowness increased by 1.06 folds and 3.34 folds when compared to clove (control), respectively. The UV barrier property 0.08±0.01nm in all films, while 8.37 folds reduction in transparency has been observed as …

Ultrafast Electron Diffraction: Visualizing Dynamic States Of Matter, D. Filippetto, P. Musumeci, R. K. Li, B. J. Siwick, M. R. Otto, Martin Centurion, J. P. F. Nunes

Department of Physics and Astronomy: Faculty Publications

Since the discovery of electron-wave duality, electron scattering instrumentation has developed into a powerful array of techniques for revealing the atomic structure of matter. Beyond detecting local lattice variations in equilibrium structures with the highest possible spatial resolution, recent research efforts have been directed toward the long-sought-after dream of visualizing the dynamic evolution of matter in real time. The atomic behavior at ultrafast timescales carries critical information on phase transition and chemical reaction dynamics, the coupling of electronic and nuclear degrees of freedom in materials and molecules, and the correlation among structure, function, and previously hidden metastable or nonequilibrium states …

Nanoclays And Curcumin Based Food Packaging Material For Intelligent Food Packaging Applications, Kalpani Y. Perera, Swarna Jaiswal, Amit K. Jaiswal, Shubham Sharma

Articles

Bionanocomposite packaging eco-friendly alternatives with enhanced characteristics. This study aimed to develop a bionanocomposite intelligent packaging. Sodium alginate, gelatin, Curcumin (Cur), glycerol, and Nanoclay (NC) films were prepared. The influences of nanoclay and curcumin on the surface, optical, mechanical, chemical, barrier, and pH-indicating properties were studied. The results showed that the lightness of films was reduced by 1.28 folds compared to NC (control) film, while the yellowness of films increased by 5.82 folds. Film transparency was reduced by 9.3 folds and a 3.46 folds increase in UV barrier properties was observed compared to NC (control) film. The highest tensile strength …

A Synopsis Of Institutional Repositories In Nigerian University System: Advantages And Challenges, Samson Adesina Akinola, Dolapo P. Olagoke, Opeyemi F. Opawale

Library Philosophy and Practice (e-journal)

The academic communities have undoubtedly been struggling for some years now with difficulties in disseminating and communicating research findings. This is as a result of the ever increasing high cost of journals, which are the traditional medium for research communication and how this as affected libraries budget, most especially in the depressed economy of developing countries. The financial difficulties being experienced by academic publishers have also added to this pain. Many academics have their research work stored in Microsoft (MS) words and other digital formats on their computers, but only very few of them ponder on the long term preservation …

Possibilities For Inertial Electrostatic Confinement Fusion, Jeffrey Edward Black

Dissertations and Theses

While most of the fusion energy research is focused on magnetic confinement, there have been several alternative confinement methods aimed at the development of smaller and less expensive reactors. A number of these devices utilize a spherically convergent beam of recirculating ions, a technique known as inertial electrostatic confinement (IEC). This study looks at several aspects of IEC devices, including measurements of the fusion rate of an IEC device with a wire mesh electrode cathode, and a solid titanium cathode. In addition, several computational studies were performed to explore the possibilities for IEC fusion. These include development of a 1D-1P …

Modulation Of Sirtuins During Monolayer Chondrocyte Culture Influences Cartilage Regeneration Upon Transfer To A 3d Culture Environment, David A Lee

Faculty, Staff and Student Publications

This study examined the role of sirtuins in the regenerative potential of articular chondrocytes. Sirtuins (SIRT1-7) play a key role in regulating cartilage homeostasis. By inhibiting pro-inflammatory pathways responsible for cartilage degradation and promoting the expression of key matrix components, sirtuins have the potential to drive a favourable balance between anabolic and catabolic processes critical to regenerative medicine. When subjected to osmolarity and glucose concentrations representative of the in vivo niche, freshly isolated bovine chondrocytes exhibited increases in SIRT1 but not SIRT3 gene expression. Replicating methods adopted for the in vitro monolayer expansion of chondrocytes for cartilage regenerative therapies, we …

Identification Of Acenkps, A Committed Common Progenitor Population Of The Ilc1 And Nk Cell Continuum, Bernhard Kerscher, Meera Sivasubramaniam, Luisa Pedro, Jennifer A Walker, Morgan W D Heycock, Jacqueline D Shields, Jillian L Barlow, Andrew N J Mckenzie

Faculty, Staff and Student Publications

The development of innate lymphoid cell (ILC) transcription factor reporter mice has shown a previously unexpected complexity in ILC hematopoiesis. Using novel polychromic mice to achieve higher phenotypic resolution, we have characterized bone marrow progenitors that are committed to the group 1 ILC lineage. These common ILC1/NK cell progenitors (ILC1/NKP), which we call "aceNKPs", are defined as lineage-Id2+IL-7Rα+CD25-α4β7-NKG2A/C/E+Bcl11b-. In vitro, aceNKPs differentiate into group 1 ILCs, including NK-like cells that express Eomes without the requirement for IL-15, and produce IFN-γ and perforin upon IL-15 stimulation. Following reconstitution of Rag2-/-Il2rg-/- hosts, aceNKPs give rise to a spectrum of mature ILC1/NK cells …

The Rheumatoid Arthritis Drug Auranofin Lowers Leptin Levels And Exerts Antidiabetic Effects In Obese Mice, Aaron R Cox, Peter M Masschelin, Pradip K Saha, Jessica B Felix, Robert Sharp, Yan Xia, David A Bader, Kang Ho Kim, Xin Li, Jun Yoshino, Xin Li, Gang Li, Zheng Sun, Huaizhu Wu, Cristian Coarfa, David D Moore, Samuel Klein, Kai Sun, Sean M Hartig

Faculty, Staff and Student Publications

Low-grade, sustained inflammation in white adipose tissue (WAT) characterizes obesity and coincides with type 2 diabetes mellitus (T2DM). However, pharmacological targeting of inflammation lacks durable therapeutic effects in insulin-resistant conditions. Through a computational screen, we discovered that the FDA-approved rheumatoid arthritis drug auranofin improved insulin sensitivity and normalized obesity-associated abnormalities, including hepatic steatosis and hyperinsulinemia in mouse models of T2DM. We also discovered that auranofin accumulation in WAT depleted inflammatory responses to a high-fat diet without altering body composition in obese wild-type mice. Surprisingly, elevated leptin levels and blunted beta-adrenergic receptor activity achieved by leptin receptor deletion abolished the antidiabetic …