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Ucc Minutes October 11, 2022, Angela Brock

UCC Agendas/Minutes

No abstract provided.

Bioactive Food Components And Their Inhibitory Actions In Multiple Platelet Pathways, Diptimayee Das, Shubhamay Adhikary, Ranjit Kumar Das, Antara Banerjee, Arun Kumar Radhakrishnan, Sujay Paul, Surajit Pathak, Asim K. Duttaroy

Health & Biomedical Sciences Faculty Publications

In addition to hemostasis and thrombosis, blood platelets are involved in various processes such as inflammation, infection, immunobiology, cancer metastasis, wound repair and angiogenesis. Platelets' hemostatic and non-hemostatic functions are mediated by the expression of various membrane receptors and the release of proteins, ions and other mediators. Therefore, specific activities of platelets responsible for the non-hemostatic disease are to be inhibited while leaving the platelet's hemostatic function unaffected. Platelets' anti-aggregatory property has been used as a primary criterion for antiplatelet drugs/bioactives; however, their non-hemostatic activities are not well known. This review describes the hemostatic and non-hemostatic function of human blood …

Expert Clinical Management Of Severe Immune-Related Adverse Events: Results From A Multicenter Survey On Hot Topics For Management, Mar Riveiro-Barciela, Maria Jose Soler, Ana Barreira-Diaz, Sheila Bermejo, Sebastian Bruera, Maria E Suarez-Almazor

Faculty, Staff and Students Publications

There are differences in recommendations for the management of immune-related adverse events (irAEs) associated with immune checkpoint inhibitors (ICIs). To assess the real-world management of irAEs, three surveys regarding ICI-induced hepatitis (IIH), renal irAEs, and myositis were developed and sent to experts in each area. Fifty-six surveys were completed (17 IIH, 20 renal irAEs, and 19 myositis). All experts agreed on performing imaging in every suspected case of severe IIH. Sixty-five percent agreed on performing a liver biopsy in patients not responding to corticosteroids. The most common indication for corticosteroid use (59%) was for severe IIH not improving after discontinuation …

Ez Clear For Simple, Rapid, And Robust Mouse Whole Organ Clearing, Chih-Wei Hsu, Juan Cerda, Jason M Kirk, Williamson D Turner, Tara L Rasmussen, Carlos P Flores Suarez, Mary E Dickinson, Joshua D Wythe

Faculty, Staff and Students Publications

Tissue clearing for whole organ cell profiling has revolutionized biology and imaging for exploration of organs in three-dimensional space without compromising tissue architecture. But complicated, laborious procedures, or expensive equipment, as well as the use of hazardous, organic solvents prevent the widespread adoption of these methods. Here, we report a simple and rapid tissue clearing method, EZ Clear, that can clear whole adult mouse organs in 48 hr in just three simple steps. Samples stay at room temperature and remain hydrated throughout the clearing process, preserving endogenous and synthetic fluorescence, without altering sample size. After wholemount clearing and imaging, samples …

Maternal Gut Microbiota Mediate Intergenerational Effects Of High-Fat Diet On Descendant Social Behavior, Claudia M Di Gesù, Lisa M Matz, Ian J Bolding, Robert Fultz, Kristi L Hoffman, Antonella Marino Gammazza, Joseph F Petrosino, Shelly A Buffington

Faculty, Staff and Students Publications

Dysbiosis of the maternal gut microbiome during pregnancy is associated with adverse neurodevelopmental outcomes. We previously showed that maternal high-fat diet (MHFD) in mice induces gut dysbiosis, social dysfunction, and underlying synaptic plasticity deficits in male offspring (F1). Here, we reason that, if HFD-mediated changes in maternal gut microbiota drive offspring social deficits, then MHFD-induced dysbiosis in F1 female MHFD offspring would likewise impair F2 social behavior. Metataxonomic sequencing reveals reduced microbial richness among female F1 MHFD offspring. Despite recovery of microbial richness among MHFD-descendant F2 mice, they display social dysfunction. Post-weaning Limosilactobacillus reuteri treatment increases the abundance of short-chain …

Whole Genome Sequence Analysis Of Blood Lipid Levels In >66,000 Individuals, Margaret Sunitha Selvaraj, Lisa De Las Fuentes, Susan K. Dutcher, Et Al.

2020-Current year OA Pubs

No abstract provided.

Telling Trauma: Resisting Through Embroidery Stories, Jharna Choudhury

Journal of International Women's Studies

As a contemporary mode of subversion, the art of needlework has been revived from the category of the merely “aesthetic” to the expansive category of the “powerful.” Freestyle hand embroidery enables the socially disabled women of South Asia and other regions of the world to vent their trauma within the walls of their households. The select set of embroideries displayed here is expressionistic in art-style, presenting three micro-stories on bride burning, female foeticide, and Eve-teasing, as part of my personal project named “Embroidery Stories.”

“Gender At The Root Of Everyday Life”: Equity, Activism, And The Perspectives Of Diana J. Fox, Goutam Karmakar

Journal of International Women's Studies

This in-depth conversation with Diana J. Fox, Professor of Anthropology at Bridgewater State University, Massachusetts, United States, and a cultural and applied anthropologist, scholar-activist, and documentary film producer, puts emphasis on how Fox’s research demonstrates that a decolonial feminist viewpoint inspires and even necessitates that Indigenous feminisms be at the center, and that researchers from the global north have a responsibility to do so. In this interview, Fox talks about how, as a feminist decolonial/anticolonial anthropologist, she has worked for global gender justice and equality throughout her career, especially within the Anglophone Caribbean, which is where the bulk of her …

Unbearable Weight: Women And The Shaping Of Political Subjects Through The Politics Of Corporeality, Meenakshi Malhotra, Krishna Menon

Journal of International Women's Studies

This article explores three moments in recent history where Indian women’s bodies—seen and unseen—highlight the centrality of the female body in the changing political discourse of India. The first moment, the Shaheen Bagh moment, is characterized by the body marked as “Muslim woman” and her occupation of public squares and streets (the protests in 2019-20 against the Citizenship Amendment Act). The second moment is the female body that engaged in unprecedented care work while being subjected to heightened levels of violence in the times of the pandemic, and the third moment is the resilient female body in struggle against neo-liberal …

Comprehending The Bleeding Body: Epistemological Violence And (Un)Tabooing Menstruation In Selective Media Texts In India, Argha Basu, Priyanka Tripathi

Journal of International Women's Studies

The representation of menstruation in Indian media texts (films, short films, and advertisements) is limited. Besides the advertisement of industrially produced sanitary napkins, we hardly come across their mention. Even in cinematic spaces with female leads, the issue remains unuttered. Since the last half of the previous decade, there has been a conscious attempt to raise awareness around menstruation. Considering menstruation as a socially mediated biological process, in which bodies become sites where social constructions of differences are mapped onto human beings to inflict violence upon the subject, these works have resisted this systematic patriarchal oppression by asking an appropriate …

Women In Afghanistan: The Ambivalence Of The Prison In Nadia Hashimi’S A House Without Windows, Tooba Rasheed

Journal of International Women's Studies

“A house without windows” literally translates to a prison. Nadia Hashimi’s novel A House without Windows (2016) personifies Afghan women’s lives as prisoners in their own bodies while also dialogically situating their stories inside a prison–Chil Mahtab. This article focuses on the semiotic relationship between the spatial prison of Chil Mahtab and the temporal prison that women live in under the hegemony of men. The violated bodies of characters like “the little girl” carry the burden of patriarchal injustices in Afghanistan. And the horrifying stories of being rejected by male institutions, particularly the law, paint a picture of Afghan society …

The Caged Bird Sings: Resilience And Resistance Against The Afghan Patriarchal Culture In Nadia Hashimi’S One Half From The East, Avijit Das, Shri Krishan Rai

Journal of International Women's Studies

In a highly conservative society like Afghanistan, which is mainly governed by ancient codes of conduct and tribal laws, the discourse concerning the rights of women is primarily framed by misogynistic men. As portrayed by Nadia Hashimi in her book One Half from the East (2016), every aspect of women’s lives, from education to expression to movement, is monitored and checked by the patriarchy through the perpetration of rigid cultural codes of conduct for women. But even within such strict patriarchal domination, women can create space for themselves to subvert such repressive hegemony and articulate strategic resistance in a culture …

Bodies In Transit: Women, War, And Violence In Select Fiction From Nepal, Lakhipriya Gogoi

Journal of International Women's Studies

The figures of women in conflict zones have been presented in South Asian literature chiefly as torn and battered bodies/souls, usually carrying an irremediable suffering and sense of loss that they bear as wives, mothers, and daughters while their male compatriots participate in the zone of war. The twentieth century surge in identity movements and political conflicts in South Asia, however, offers us new figures of women as “warriors” or direct participants in the zones of violence. The usurpation of such new bodies, on the one hand, defies the hegemonic feminization of women’s bodies as caregivers, and on the other …

Gender, Sexuality And Representation In Pakistani Literature: Qandeel Baloch As A Victim Of Honor Killing, Nukhbah Taj Langah, Sumera Umrani

Journal of International Women's Studies

The article discusses women’s bodies as victims of violence by regarding gender as a stereotype as compared to a social construct within the context of Pakistan. The primary sources for this analysis are a sample of investigative journalism based on the life of a Pakistani social media figure Qandeel Baloch as depicted in The Sensational Life and Death of Qandeel Baloch (2018) by Sanam Maher. We contend that the conventional expectations of women in Pakistan have resulted in crimes like honor killing. Through textual analysis of Maher’s account, we debate the concept of honor killing within the Pakistani context, with …

Cultural Violence, Violent Gendering, And Abjection: Discourses On Sites Of Violence Through Trans Women’S Narratives From India, Tanupriya, Dhishna Pannikot

Journal of International Women's Studies

The conventional cultural construct of gender and sexuality embedded in the dichotomous paradigm makes it challenging for people with queer and trans identities to fit into an assigned social role. Violent gendering takes place where women are seen as second-order beings, disciplined and controlled by men, the first-order beings. The process of feminization and femininity is linked to women, which fixates on the idea that “one is born a woman” rather than “one becomes a woman.” This violent process of acculturation to these set norms comes with a lot of vulnerability for trans people in the form of abiding by …

Labour As Violence In Dalit Households: Reading Autobiographical Narratives By Dalit Women, Pratibha

Journal of International Women's Studies

The everyday concerns of Dalit women are frequently overlooked in discourses about the emancipation of Dalits from Brahminical hegemony in favor of issues deemed weightier, such as reform ideology, caste conflicts, and political power struggles. The micro-politics of the sexual division of labour in Dalit households, with its corrosive effects on the well-being and self-perception of Dalit women, has remained side-lined. Even when discussed with reference to caste and gender intersectionality, the labour consigned to Dalit women is spoken of in additive terms to explicate their “double oppression” or victimisation through sexual exploitation at the hands of upper caste men. …

Of Contested Landscapes And Women’S Bodies: Rape As An Invasive Weapon In Malsawmi Jacob’S Zorami, Debajyoti Biswas, Zothanchhingi Khiangte

Journal of International Women's Studies

The geopolitical history of India’s Northeast replicates the history of the struggle of the ethnic communities living along what is often referred to as a “troubled periphery.” The fictionalised stories produced in this region, therefore, often betray the wounds inflicted on people living in this contested territory. As such, the history of this place and the story of its people lose their distinctions, allowing ethnographic study and the fluidity of personal narrative to converge and inform each other. Malsawmi Jacob’s Zorami (2018) encapsulates this history of strife and contestation through emphasizing a double significance in the eponymous character symbolising both …

On Violence And Resistance: Narratives Of Women In South Asia, Goutam Karmakar

Journal of International Women's Studies

No abstract provided.

Keys To Genus Of Calanoid Copepods Of China Seas, Chang-Tai Shih, Qing-Chao Chen, Yang-Chi Lan, Shih-Hui Hsiao, Chi-Yu Weng

Journal of Marine Science and Technology–Taiwan

No abstract provided.

Calanoid Copepods Of China Seas, Chang-Tai Shih, Qing-Chao Chen, Yang-Chi Lan, Shih-Hui Hsiao, Chi-Yu Weng

Journal of Marine Science and Technology–Taiwan

Calanoid copepods are a well-recognized taxonomic group of Crustacea. They were already placed, with one cyclopoid (Scribella) and five calanoid (Acartia, Calanus, Candacia, Euchirus (= Euchaeta), and Pontella) genera, under a single taxonomic unit, the Calanidae, by Dana [1]. Giesbrecht and Sars are the two early principal contributors to the taxonomy of Copepoda, including the Calanoida.

Based on the location of the body articulation, Giesbrecht [2] divided copepods into two groups, the Gymnopleoden and Podopleoden. All copepods, characterized by an articulation between the fifth pedigerous (leg-bearing) somite and genital somite, separating the body into an anterior part (prosome) and a …

Calanoid Copepods Of China Seas-Introduction And Acknowledgement, Chang-Tai Shih, Qing-Chao Chen, Yang-Chi Lan, Shih-Hui Hsiao, Chi-Yu Weng

Journal of Marine Science and Technology–Taiwan

No abstract provided.

التحرر العقلاني واللاعقلاني للمرأة في ظل المجتمع: دراسة تحليلية نقدية لـ رواية (سولا) لتوني مورسون, م.م. محمد صبار عبد الباقي

Midad AL-Adab Refereed Quarterly Journal

تعد توني مورسون (18 فبراير، 1931) من ابرز الروائيات الامريكيات من اصل افريقي والتي سعت بكل الوسائل لتحقيق تحرر المرأة. تعد مورسون واحدة من اهم مناصري النسوية واكثرهم شهرة وذلك من خلال رواياتها المتضمنة اصداء التحرر. يسلط البحث الضوء على عقلانية قرارات المرأة ومواقفها في بحثها عن التحرروبصورة خاصة لشخصيتي سولا ونيل. يهدف البحث اولا الى مناقشة اهمية عقلانية المرأة في مجتمعها وثانيا الى تجنب انحرافات المرأة التي قد تمحو مكانتها وتقلل من فرصها للتحرر. يدور البحث حول الالتزام العقلاني والاخلاقي لـ(نيل) والذي يعزز تحررها الاجتماعي ويحلل كذلك لا عقلانية (سولا) الذي يؤدي الى تحرر عابرومشين وذلك لما يتضمنه من …

Genomic Data Mining Reveals Abundant Uncharacterized Transporters In Coccidioides Immitis And Coccidioides Posadasii, Hong Cai, Hao Zhang, Daniel H. Guo, Yufeng Wang, Jianying Gu

Publications and Research

Coccidioides immitis and Coccidioides posadasii are causative agents of coccidioidomycosis, commonly known as Valley Fever. The increasing Valley Fever cases in the past decades, the expansion of endemic regions, and the rising azole drug-resistant strains have underscored an urgent need for a better understanding of Coccidioides biology and new antifungal strategies. Transporters play essential roles in pathogen survival, growth, infection, and adaptation, and are considered as potential drug targets. However, the composition and roles of transport machinery in Coccidioides remain largely unknown. In this study, genomic data mining revealed an abundant, uncharacterized repertoire of transporters in Coccidioides genomes. The catalog …

Kyle Adams And Ummu Bah Are The 2022-2023 Mr. And Ms. Uab, Shannon Thomason

Browse All News

No abstract provided.

Unique Thermal Sensitivity Imposes A Cold-Water Energetic Barrier For Vertical Migrators, Brad Seibel, Matthew A. Birk

Marine Science Faculty Publications

Alterations of marine species’ ranges with climate change are often attributed to oxygen limitation in warming oceans. Here we report unique metabolic temperature sensitivities for the myriad of vertically migrating oceanic species that daily cross depth-related gradients in temperature and oxygen. In these taxa, selection favours high metabolic activity for predator–prey interactions in warm shallow water and hypoxia tolerance in the cold at depth. These diverging selective pressures result in thermal insensitivity of oxygen supply capacity and enhanced thermal sensitivity of active metabolic rate. Aerobic scope is diminished in the cold, well beyond thermodynamic influences and regardless of ambient oxygen …

Direct Measurement Of Stokes–Einstein Diffusion Of Cowpea Mosaic Virus With 19 Μs-Resolved Xpcs, Kacper Switalski, Jingyu Fang, Luxi Li, Miaoqi Chu, Erik Sarnello, Pete Jemian, Tao Li, Qian Wang, Qingteng Zhang

Faculty Publications

Brownian motion of Cowpea mosaic virus (CPMV) in water was measured using small-angle X-ray photon correlation spectroscopy (SA-XPCS) at 19.2 mu s time resolution. It was found that the decorrelation time tau(Q) = 1/DQ(2) up to Q = 0.091 nm(-1). The hydrodynamic radius R-H determined from XPCS using Stokes-Einstein diffusion D = kT/(6 pi eta R-H) is 43% larger than the geometric radius R-0 determined from SAXS in the 0.007 M K3PO4 buffer solution, whereas it is 80% larger for CPMV in 0.5 M NaCl and 104% larger in 0.5 M (NH4)(2)SO4, a possible effect of aggregation as well as …

Factors Influencing Terrestriality In Primates Of The Americas And Madagascar, Timothy M. Eppley, Selwyn Hoeks, Colin A. Chapman, Joerg U. Ganzhorn, Katie Hall, Megan A. Owen, Dara B. Adams, Néstor Allgas, Multiple Additional Authors

Anthropology Faculty Publications and Presentations

Among mammals, the order Primates is exceptional in having a high taxonomic richness in which the taxa are arboreal, semiterrestrial, or terrestrial. Although habitual terrestriality is pervasive among the apes and African and Asian monkeys (catarrhines), it is largely absent among monkeys of the Americas (platyrrhines), as well as galagos, lemurs, and lorises (strepsirrhines), which are mostly arboreal. Numerous ecological drivers and species-specific factors are suggested to set the conditions for an evolutionary shift from arboreality to terrestriality, and current environmental conditions may provide analogous scenarios to those transitional periods. Therefore, we investigated predominantly arboreal, diurnal primate genera from the …

Direct Material Property Determination: One-Dimensional Formulation Utilising Full-Field Deformation Measurements, Sreehair Rajan-Kattil, Michael A. Sutton, Subramani Sockalingam, Frank Thomas, Tusit Weerasooriya, Stephen Alexander

Faculty Publications

A direct approach is described to determine the elastic modulus distribution in a nominally heterogeneous material subject to tensile/compression loading and primarily experiencing deformations in the axial direction. The formulation is developed for uniaxial applications using basic theoretical constructs, resulting in a computational framework that has a matrix form [A] {E} = {R}, where the [A] matrix components are known functions of measured axial strains and axial positions, {R} components are known functions of axial body forces, applied loads and reactions and {E} components are the unknown elastic moduli at discrete locations along the length of the specimen. For a …

The Exercise Metabolome: Acute Aerobic And Anaerobic Signatures, Joseph K. Pellegrino, Tracy G. Anthony, Peter Gillies, Shawn M. Arent

Faculty Publications

Background

Exercise modality differentially alters body composition and physical performance. Metabolic changes underlying these outcomes can be tracked through assessment of circulating metabolites. Here, global responses to an acute bout of aerobic or anaerobic exercise were compared in the serum of male and female subjects using a discovery-based metabolomics platform.

Methods

On separate days, 40 healthy, active participants completed 45 min of aerobic cycling or resistance exercise, and blood samples were collected at rest, immediately after (T1) and 1 hour post-exercise (T2) to examine the serum metabolomic landscape.

Results

The two exercise metabolomes appeared more similar than different in this …

Attenuation Of Relapsing Fever Neuroborreliosis In Mice By Il-17a Blockade, Meihui Cheng, Jingwen Xu, Kaiyun Ding, Jing Zhang, Wei Lu, Jiansheng Liu, Jiahong Gao, Kishore R Alugupalli, Hongqi Liu

Department of Microbiology and Immunology Faculty Papers

Relapsing fever due to Borrelia hermsiiis characterized by recurrent bacteremia episodes. However, infection of B. hermsii, if not treated early, can spread to various organs including the central nervous system (CNS). CNS disease manifestations are commonly referred to as relapsing fever neuroborreliosis (RFNB). In the mouse model of B. hermsiiinfection, we have previously shown that the development of RFNB requires innate immune cells as well as T cells. Here, we found that prior to the onset of RFNB, an increase in the systemic proinflammatory cytokine response followed by sustained levels of IP-10 concurrent with the CNS disease phase. RNA sequencing …