Digital Commons Network^™

Terminal Field Volume Of The Glossopharyngeal Nerve In Adult Rats Reverts To Prepruning Size Following Microglia Depletion With Plx5622, Andrew J. Riquier, Suzanne I. Sollars

Psychology Faculty Publications

Programmed reduction of synapses is a hallmark of the developing brain, with sensory systems emerging as useful models with which to study this pruning. The central projections (terminal field) of the gustatory glossopharyngeal nerve (GL) of the rat are a prime example of developmental pruning, undergoing an approximate 66% reduction in volume from postnatal day 15 (P15) to P25. Later in adulthood, developmental GL pruning can be experimentally reversed, expanding to preweaning volumes, suggesting mature volumes may be actively maintained throughout the life span. Microglia are central nervous system glia cells that perform pruning and maintenance functions in other sensory …

Administration Of Broadly Neutralizing Anti-Hiv-1 Antibodies At Art Initiation Maintains Long-Term Cd8+ T Cell Immunity, Miriam Rosás-Umbert, Jesper D. Gunst, Marie H. Pahus, Rikke Olesen, Mariane H. Schleimann, Paul W. Denton, Victor Ramos, Adam R. Ward, Natalie N. Kinloch, Dennis C. Copertino, Tuixent Escribà, Anuska Llano, Zabrina L. Brumme, R. Brad Jones, Beatriz Mothe, Christian Brander, Julie Fox, Michel C. Nussenzweig, Sarah Fidler, Marina Caskey, Martin Tolstrup, Ole S. Søgaard

Biology Faculty Publications

In simian-human immunodeficiency virus (SHIV)-infected non-human primates, broadly neutralizing antibodies (bNAbs) against the virus appear to stimulate T cell immunity. To determine whether this phenomenon also occurs in humans we measured HIV-1-specific cellular immunity longitudinally in individuals with HIV-1 starting antiviral therapy (ART) with or without adjunctive bNAb 3BNC117 treatment. Using the activation-induced marker (AIM) assay and interferon-γ release, we observe that frequencies of Pol- and Gag-specific CD8+ T cells, as well as Gag-induced interferon-γ responses, are significantly higher among individuals that received adjunctive 3BNC117 compared to ART-alone at 3 and 12 months after starting ART. The observed changes in …

International Conference On Architecture And Spatial Planning, University For Business And Technology - Ubt

UBT International Conference

UBT Annual International Conference is the 11th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make them be aware of the recent …

International Conference On Food Science, University For Business And Technology - Ubt

UBT International Conference

UBT Annual International Conference is the 11th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make them be aware of the recent …

International Conference On Computer Science, University For Business And Technology - Ubt

UBT International Conference

UBT Annual International Conference is the 11th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make them be aware of the recent …

International Conference On Mechatronic, University For Business And Technology - Ubt

UBT International Conference

UBT Annual International Conference is the 11th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make them be aware of the recent …

International Conference On Political Science, University For Business And Technology - Ubt

UBT International Conference

UBT Annual International Conference is the 11th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make them be aware of the recent …

A Membrane Transporter Required For Quorum Sensing And Virulence Of The Rice Pathogen Burkholderia Glumae, Asif Iqbal

LSU Doctoral Dissertations

Burkholderia glumae is a Gram-negative bacterium causing bacterial panicle blight (BPB) in rice. BPB can cause severe damage to rice and reduce rice yield up to 75%, while no effective treatment has been developed to control the disease. B. glumae produces and secretes an essential virulence factor, toxoflavin, which is mainly responsible for the symptoms of BPB. Synthesis and transport of toxoflavin are regulated in a quorum-sensing dependent manner. Members of the DedA superfamily are putative membrane transporters and found in nearly all species. Mutation of dedA in Burkholderia species results in sensitivity to colistin, an antibiotic belonging to the …

International Conference On Dental Science, University For Business And Technology - Ubt

UBT International Conference

UBT Annual International Conference is the 11th international interdisciplinary peer reviewed conference which publishes works of the scientists as well as practitioners in the area where UBT is active in Education, Research and Development. The UBT aims to implement an integrated strategy to establish itself as an internationally competitive, research-intensive university, committed to the transfer of knowledge and the provision of a world-class education to the most talented students from all background. The main perspective of the conference is to connect the scientists and practitioners from different disciplines in the same place and make them be aware of the recent …

Mirnas: The Key Regulator Of Covid-19 Disease, Leyla T. Hardin, Nan Xiao

Pacific Faculty Work

As many parts of the world continue to fight the innumerable waves of COVID-19 infection, SARS-CoV-2 continues to sculpt its antigenic determinants to enhance its virulence and evolvability. Several vaccines were developed and used around the world, and oral antiviral medications are being developed against SARS-CoV-2. However, studies showed that the virus is mutating in line with the antibody's neutralization escape; thus, new therapeutic alternatives are solicited. We hereby review the key role that miRNAs can play as epigenetic mediators of the cross-talk between SARS-CoV-2 and the host cells. The limitations resulting from the "virus intelligence"to escape and antagonize the …

Effective Integration Of Molecular Spectroscopy In Undergraduate Research Experiences, Khalique Ahmed

Faculty and Staff Publications & Presentations

STEM research has proven to be beneficial in students learning, retention and graduation rates, entry into to the graduate and professional programs, and development of the critical thinking and soft skills. Considering this, it would not be wrong to classify STEM research engagement as a panacea of quality student outcomes. Keeping this in mind, over the last two decades as a professor at mainly an undergraduate institution in South Florida, I have engaged students in assortment of highly practical and publishable research topics in the area of molecular spectroscopy. Whereas at most institutions the focus of molecular spectroscopy is mainly …

Establishing The Non-Canonical Nature Of A Leucyl-Trna Synthetase Paralog In Sulfolobus Islandicus, Jonathan Blair Brewster

Theses and Dissertations

Aminoacyl-tRNA synthetases (aaRSs) are essential proteins. Their canonical function is to catalyze the attachment of amino acids to cognate tRNA. The organism Sulfolobus islandicus contains two aaRSs for leucine. These leucyl-tRNA synthetase (LeuRS) paralogs were previously studied using a single tRNALeu isoacceptor, tRNALeu-UAG. One leucyl-tRNA synthetase, LeuRS-F, was shown to faithfully perform the necessary function of charging, the process of catalytically attaching leucine to tRNALeu. Furthermore, the essentiality of LeuRS-F was emphasized by an inability to remove its gene from S. islandicus. The paralog, LeuRS-I, was shown to have no aminoacylation activity, compared to LeuRS-F, even though it could activate …

Inhibition Of Colorectal Cancer Tumorigenesis By Ursolic Acid And Doxorubicin Is Mediated By Targeting The Akt Signaling Pathway And Activating The Hippo Signaling Pathway, Masashi Fujita, Mei-Ju May Chen, Doris Rieko Siwak, Shota Sasagawa, Ayako Oosawa-Tatsuguchi, Koji Arihiro, Atsushi Ono, Ryoichi Miura, Kazuhiro Maejima, Hiroshi Aikata, Masaki Ueno, Shinya Hayami, Hiroki Yamaue, Kazuaki Chayama, Ju-Seog Lee, Yiling Lu, Gordon B Mills, Han Liang, Satoshi S Nishizuka, Hidewaki Nakagawa

Faculty, Staff and Student Publications

Primary liver cancer is a heterogeneous disease in terms of its etiology, histology, and therapeutic response. Concurrent proteomic and genomic characterization of a large set of clinical liver cancer samples can help elucidate the molecular basis of heterogeneity and thus serve as a valuable resource for personalized liver cancer treatment. In this study, we perform proteomic profiling of ~300 proteins on 259 primary liver cancer tissues with reverse-phase protein arrays, mutational analysis using whole genome sequencing and transcriptional analysis with RNA-Seq. Patients are of Japanese ethnic background and mainly HBV or HCV positive, providing insight into this important liver cancer …

Proteo-Genomic Characterization Of Virus-Associated Liver Cancers Reveals Potential Subtypes And Therapeutic Targets, Masashi Fujita, Mei-Ju May Chen, Doris Rieko Siwak, Shota Sasagawa, Ayako Oosawa-Tatsuguchi, Koji Arihiro, Atsushi Ono, Ryoichi Miura, Kazuhiro Maejima, Hiroshi Aikata, Masaki Ueno, Shinya Hayami, Hiroki Yamaue, Kazuaki Chayama, Ju-Seog Lee, Yiling Lu, Gordon B Mills, Han Liang, Satoshi S Nishizuka, Hidewaki Nakagawa

Faculty, Staff and Student Publications

Primary liver cancer is a heterogeneous disease in terms of its etiology, histology, and therapeutic response. Concurrent proteomic and genomic characterization of a large set of clinical liver cancer samples can help elucidate the molecular basis of heterogeneity and thus serve as a valuable resource for personalized liver cancer treatment. In this study, we perform proteomic profiling of ~300 proteins on 259 primary liver cancer tissues with reverse-phase protein arrays, mutational analysis using whole genome sequencing and transcriptional analysis with RNA-Seq. Patients are of Japanese ethnic background and mainly HBV or HCV positive, providing insight into this important liver cancer …

Desmoglein-2 Is Important For Islet Function And Β-Cell Survival, Kay K. Myo Min, Darling Rojas-Canales, Daniella Penko, Mark Denichilo, Michaelia P. Cockshell, Charlie B. Ffrench, Emma J. Thompson, Olof Asplund, Christopher J. Drogemuller, Rashmi B. Prasad, Leif Groop, Shane T Grey, Helen E. Thomas, Thomas Loudovaris, Thomas W. Kay, My G. Mahoney, Claire F. Jessup, P. Toby Coates, Claudine S. Bonder

Department of Dermatology and Cutaneous Biology Faculty Papers

Type 1 diabetes is a complex disease characterized by the lack of endogenous insulin secreted from the pancreatic β-cells. Although β-cell targeted autoimmune processes and β-cell dysfunction are known to occur in type 1 diabetes, a complete understanding of the cell-to-cell interactions that support pancreatic function is still lacking. To characterize the pancreatic endocrine compartment, we studied pancreata from healthy adult donors and investigated a single cell surface adhesion molecule, desmoglein-2 (DSG2). Genetically-modified mice lacking Dsg2 were examined for islet cell mass, insulin production, responses to glucose, susceptibility to a streptozotocin-induced mouse model of hyperglycaemia, and ability to cure diabetes …

Concentration Of Heavy Metals In Three Distinct Algae Families From Humboldt County, California, Kodiak E. Miller, Caleb J. Strait, Jacob I. Begorre, Brittney L. Mitchell, Claire P. Till

IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt

Anthropogenic impacts on marine environments can impact metal fluxes and concentrations available to marine species. Monitoring these impacts is necessary to better understand the interactions between the biotic and abiotic components of these ecosystems and mitigate the risk posed by harmful toxins introduced by human activities. Biomoniters, like macroscopic algae, are useful indicators that illuminate the bioaccumulation of toxins commonly introduced from anthropogenic activity. With this in mind, the concentrations of heavy metals zinc (Zn), nickel (Ni), and copper (Cu) were analyzed via the assessment of algae (Representatives from Ulva, Mastocarpus, Fucus) in two sites in Humboldt County: …

List Of Fish Species Present In Galápagos, Ecuador, And California, U.S.A., With Notes On Their Commercial Importance And Conservation Status, Erin J. Hanson, Jose R. Marin Jarrin

IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt

No abstract provided.

Variation In Coastal Macroinvertebrate Species Diversity On Intertidal Boulders In Trinidad, California., Louis Antonelli, Alexandra Winkler, Theron Taylor, Natalie Greenleaf

IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt

Coastal environments of Humboldt County provide an optimal habitat for a diversity of macroinvertebrates. This study’s focus is to determine the differences in diversity of coastal macroinvertebrate (CM) species on intertidal boulders. Eleven CM species were visually counted within a one-square-meter quadrat along two height strata of five intertidal boulders. Based upon the Shannon-Wiener diversity index, diversity was measured between the CM species in the lower region (0-1 meter from base of boulder) and the upper region (1-2 meters from base of boulder). The resulting data showed the lower regions of the boulders had a higher average diversity rating, as …

S.O.S., Sondra P. Schwetman

IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt

There are two major bodies of work I generate: one is based on three-dimensional clothing construction, and the other is allegorical figurative work. Both bodies of work display their own poetry. Working with materials such as: Forton MG resin, fibers, bronze, found objects, etc., I feel that possessing knowledge in as many mediums as possible is necessary so that one can achieve a “vision” that is a basis for communication. It is my desire to start a dialogue about women’s issues, cultural change, and contemporary miasma. S.O.S. addresses a variety of related issues: bearing witness to our current times, social …

Full Issue 2022 (Vol 6)

IdeaFest: Interdisciplinary Journal of Creative Works and Research from Cal Poly Humboldt

No abstract provided.

Coral X-Radiograph Densitometry System, Nova Southeastern University

NSU Software

The Coral X-radiograph Densitometry System (CoralXDS) is a Windows-based program which provides a tool for measurement of linear extension, density, and calcification from coral X-radiographs. These quantities are determined for high-density, low-density, and annual bands. CoralXDS operates in two "modes": full mode and extension/luminance mode. Full mode measures linear extension, density, and calcification, while extension/luminance mode measures only linear extension. Extension/luminance mode requires only a coral image with scaling information. CoralXDS allows user specification of transect location and orientation on the coral image, and provides several options for automated and manual band selection. The output measurements …

Cpce Software, Nova Southeastern University

NSU Software

The CPCe (Coral Point Count with Excel extensions) program is a Windows-based software (PC use only) that provides a tool for the determination of coral cover using transect photographs. A specified number of spatially random points are distributed on a transect image and the features underlying the points are user-identified. Coverage statistics are then calculated and the results sent to Excel spreadsheets automatically.

Additionally, CPCe can be used for image calibration and area analysis of benthic features. Excel sheets are automatically generated to summarize the area calculations for each image.

Using CPCe

Using CPCe is simple and straightforward. The main …

The Fierce Green Fire: Vol. 13 Issue 6, Wofford College. Department Of Environmental Studies

The Fierce Green Fire

No abstract provided.

Ca2+ Entry Units In A Superfast Fish Muscle, James Matthew Kittelberger, Clara Franzini-Armstrong, Simona Boncompagni

Biology Faculty Publications

Over the past two decades, mounting evidence has demonstrated that a mechanism known as store-operated Ca2+ entry (SOCE) plays a crucial role in sustaining skeletal muscle contractility by facilitating Ca2+ influx from the extracellular space during sarcoplasmic reticulum (SR) Ca2+ depletion. We recently demonstrated that, in exercised fast-twitch muscle from mice, the incidence of Ca2+ entry units (CEUs), newly described intracellular junctions between dead-end longitudinal transverse tubular (T-tubule) extensions and stacks of sarcoplasmic reticulum (SR) flat cisternae, strictly correlate with both the capability of fibers to maintain contractions during fatigue and enhanced Ca2+ influx via SOCE. Here, we tested the …

Rodgers & Hammerstein's Cinderella (Program)

Theatre Programs and Posters

Performed October 28-29, 2022 at 8 p.m. in the Benson Auditorium as part of the Homecoming festivities.

Cast:
Ella: Emma Myhan
Topher: Asher Patten
Marie: Jonna Marie Fields
Madame: Hannah Haddix
Gabrielle: Josie Holman
Charlotte: Anna Kate Wright
Jean-Michel: Keller Montgomery
Sebastian: Merek Hailey
Lord Pinkerton: Jackson Samuel
Ensemble: Chip Ashley, Kessler Baker, McKinlee Bailey, Trey Bailey, Daniel Bennett, T.J. Brown, Julie Cmelik, Rachel Deidiker, Matthew Floyd, Campbell Gilreath, Audra Graves, Aubrey Jones, Stella Jones, Ethan Killie, Andrew Medley, Janie Shasteen, Nicole Randall, Corinne Tabor, Mckenna Watts

Curriculum Subcommittee Agenda, November 3, 2022, Utah State University

Educational Policies Committee

• Approval of Minutes - October 6, 2022
• Program Proposals
• Semester Course Approval Reviews
• Other Business
• Adjourn: 3:00 pm

Microalbuminuria And Hypertension Among Immigrants With Type 2 Diabetes: A Community-Based Cross-Sectional Study, Shiryn D. Sukhram, Gustavo G. Zarini, Lemia H. Shaban, Joan A. Vaccaro, Fatma G. Huffman

Publications and Research

Purpose: This study examined the association of microalbuminuria (MAU), as determined by albumin-to-creatinine ratio (ACR), with hypertension (HTN) among Turkish immigrants with type 2 diabetes (T2D) living in deprived neighborhoods of The Hague, Netherlands. Methods: A total of 110 participants, physician-diagnosed with T2D, aged ≥ 30 years were recruited from multiple sources from The Hague, Netherlands in a cross-sectional design. Systolic blood pressure (SBP) and diastolic blood pressure (DBP) were measured using automated office blood pressure equipment. Urine albumin was measured by immunoturbidimetric assay. Urine creatinine was determined using the Jaffe method. MAU was defined as ACR ≥ 3.5 mg/mmol …

Novel Thioglycosides As Versatile Glycosyl Donors For Oligosaccharide Synthesis, Ganesh Shrestha

Dissertations

This thesis is dedicated to the development of new methodologies for efficient synthesis of carbohydrate building blocks and their application to chemical glycosylation. S-Indolyl (SIn) anomeric moiety was investigated as a new leaving group. Understanding of the reaction pathways for the SIn moiety activation was achieved via the extended mechanistic study. The activation profile of indolylthio glycosides required large excess of activators. This drawback was partially addressed by the development of N-alkylated SInR derivatives. The activation process was studied by NMR and the increased understanding of the mechanism led to a discovery of different activation pathways taking place with …

Host Selection And Nesting Behavior Of Nearctic Trapdoor Spider-Hunting Spider Wasps (Hymenoptera: Pompilidae: Pepsinae, Pompilinae), Frank E. Kurczewski, Rick C. West

Insecta Mundi

Host records and nesting behavior of the Nearctic trapdoor spider-hunting spider wasps (Hy­menoptera: Pompilidae) Calopompilus Ashmead and Priocnemissus Haupt (Pepsinae: Pepsini) and Aporus Spinola and Psorthaspis Banks (Pompilinae: Aporini) are reviewed, investigated, compared, and discussed. First time incidental trapdoor spider host records for Priocnemis (Priocnemissus) minorata Banks (Pepsi­nae: Pepsini), Anoplius (Lophopompilus) carolina (Banks) (Pompilinae: Pompilini), and Notocyphus dorsalis dorsalis Cresson (Notocyphinae: Notocyphini) are included, although they are not typical trapdoor spider-hunting spider wasp species. The Palearctic Aporus (Aporus) unicolor Spinola, A. (Aporus) bicolor Spinola and A. (Aporus) planiceps (Latreille) are …

First Host Record, Nesting Behavior, And Taxonomic Position Of The Spider Wasp Genus Hesperopompilus Evans And Some Other Evans Genera (Hymenoptera: Pompilidae), Frank E. Kurczewski, Rick C. West, James P. Pitts

Insecta Mundi

First host record, prey transport, and burrow excavation are described for Hesperopompilus sp., an undescribed, rare spider wasp (Hymenoptera: Pompilidae) from Texas. Taxonomic, ecological, and behav­ioral examination of the genus subsequently led to an investigation of the previously related Perissopompilus Evans and Xerochares Evans. Taxonomic, host preference, nesting behavior, and phylogenomic relationships of the three taxa are discussed along with those of Xenopompilus Evans. The molecular connection of Perisso­pompilus and Allochares Banks is supported by their common use of host species of Filistatidae.

Evans (1951), in his taxonomic study of the spider wasp tribe Pompilini (Hymenoptera: Pompilidae: Pompilinae), described the …