Digital Commons Network^™

Fall/Winter 2022: Fresh Look At A Fraught History, St. Norbert College

St. Norbert College Magazine 2019-2023

St. Norbert College faculty and staff engaged with Israeli and Palestinian communities on a summer trip exploring the region’s history, religious perspectives, and human rights issues—including water access—through immersive, multi-disciplinary learning experiences.

Fall/Winter 2022: Fund Of Knowledge, Trisha Lawless

St. Norbert College Magazine 2019-2023

A magnanimous total of five National Science Foundation grants are among multiple sources currently financing cutting-edge research at St. Norbert. The thrill of discovery is an essential part of the educational journey for students and faculty at St. Norbert College. It’s a journey in which the college finds willing partners – among them the National Science Foundation (NSF). SNC currently has five active research grants from the influential federal agency.

Fall/Winter 2022: A Ministry Of Presence, St. Norbert College

St. Norbert College Magazine 2019-2023

St. Norbert College’s Norbertine clergy for 2022–23 provide a “ministry of presence” by engaging students through liturgy, academics, faith programs, and recreational activities, supporting spiritual growth and fostering community on campus.

Exploring Physiology Instructors’ Use Of Core Concepts: Pedagogical Factors That Influence Choice Of Course Topics, Jeremy L. Hsu, Patricia A. Halpin

Biology, Chemistry, and Environmental Sciences Faculty Articles and Research

The physiology core concepts are designed to guide instructors in undergraduate physiology courses. However, although past work has characterized the alignment of physiology programs with the core concepts, it is unclear to what extent these core concepts have influenced instructors’ pedagogical decisions or how represented these core concepts are across physiology courses. We surveyed undergraduate physiology instructors to determine their familiarity with the core concepts, the impact of the core concepts on their teaching, as well as the alignment of their courses with these core concepts. Instructors report predominantly relying on textbooks and past syllabi of their courses as resources …

Effects Of A Professional Learning Experience On Middle School Teachers’ Perceptions, Experiences, And Implementation Of Curricular-Embedded Self-Regulated Learning And Motivation, Samuel Baillie

Doctor of Education in Teacher Leadership Dissertations

During the middle school transitional years, students face potential obstacles that can affect their achievement and motivation. It is essential that they learn how to self-regulate their learning and motivation so that they can persevere in an increasingly challenging academic environment. Teachers may support students directly or indirectly by embedding various practices and strategies into extant curricula. This two-phase qualitative case study provided four purposively selected teachers with a professional learning (PL) experience on self-regulated learning (SRL) and self-regulated motivation (SRM). The purpose of this study was to understand the perceptions and experiences of middle school teachers regarding the training …

Intouch Week Of October 31, 2022, New York Medical College

InTouch

• NYMC Honors Distinguished Faculty and Alumni at Annual Founder’s Dinner
• Students Get Creative with Pumpkin Carving
• NYMC Participates in Black Men in White Coats Youth Summit
• SHSP Participates in United Nations Day
• NYMC and TU Present 22nd COVID-19 Symposium
• Skyline Café Food Mart Set to Open November 3

Altering Brain Amyloidosis By Intra-Lingual And Extra-Nasal Exposure Of Aβ Aggregates, Nazaret Gamez, Javiera Bravo-Alegria, Yumeng Huang, Nelson Perez-Urrutia, Deepa Dongarwar, Claudio Soto, Rodrigo Morales

Faculty, Staff and Student Publications

Extensive experimental and human-derived evidence suggest that misfolded Aβ particles spread similarly to infectious prions. Moreover, peripheral administration of Aβ seeds accelerates brain amyloidosis in both susceptible experimental animals and humans. The mechanisms and elements governing the transport of misfolded Aβ from the periphery to the brain are not fully understood, although circulation and retrograde axonal transport have been proposed. Here, we demonstrate that injection of Aβ seeds in the tongue, a highly innervated organ, substantially accelerates the appearance of plaques in Tg2576 mice. In addition, the extra-nasal exposure of Aβ aggregates increased amyloid pathology in the olfactory bulb. Our …

Analisis Bibliometrik Penelitian Dengan Tema "Digital Archive", Edi Wibowo, Tamara Adriani Salim

Jurnal Ilmu Informasi, Perpustakaan, dan Kearsipan

This study aims to analyze the development of the topic of digital archives in order to find solutions to various problems in managing digital archives with the risks caused by the creation of digital archives. The method used is literature review related to digital archives published between 1982 and 2022 taken from Scopus database. “Digital archives” is used as a keyword to reach relevant publications. VOSviewer was applied to perform a bibliometric analysis of this article. A total of 1218 publications on the topic of digital archives with a total link strength of 1821 appeared as the most frequent keywords, …

Improving Students' Critical Thinking In Biology Learning Through Reading, Concept Mapping-Team Quiz, Meiliana Dwi Cahya, Siti Zubaidah, Munzil Munzil, Azizul Ghofar Candra Wicaksono

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

This study aimed to examine an increase in students' critical thinking in biology following the implementation of the Reading Concept Mapping-Team Quiz (Remap-TQ). The study employed a quasi-experimental pretest-posttest non-equivalent control group design. The research population contained all eleventh graders from seven science classes at SMAN 2 Tanggul Jember, East Java, and the total number of respondents was 105 students. This study's critical thinking indicators include applying, evaluating, using data to develop critical insight, analysing, and synthesising. The analysis showed that the Remap-TQ students achieved better than the TQ and conventional students in terms of critical thinking, indicated by their …

The Effects Of Surface Composition On 6-Weeks Of Plyometric Training, Cameron D. Addie, Richard S. Farley, Sandra L. Stevens, Halle J. Brandt3, Jocelyn E. Arnett, Jennifer L. Caputo

Department of Nutrition and Health Sciences: Faculty Publications

Background: Plyometric training programs may be performed on a hard surface or a soft surface to target specific training adaptations and enhance jump performance. However, it is unknown how surface compliance impacts jump performance. Objective: To compare changes in horizontal lower body power following a 6-week plyometric training program performed on a soft surface (n = 9) and a hard surface (n = 11). Methods: This was a quasi-experimental study. University students (N = 20; males = 11, females = 9; age: 20.4 ± 3.7 yr; body mass: 68.4 ± 12.5 kg; height 1.7 …

Increased Nitrate Intake From Beetroot Juice Does Not Alter Soluble Cellular Adhesion Molecules And Circulating Inflammatory Cytokines In Individuals With Treated Hypertension: A Randomised, Controlled Trial, Kyle Raubenheimer, Alex H. Liu, Henrietta Koch, Erika Bosio, Nicola P. Bondonno, Vance Matthews, Marc Sim, Lauren Blekkenhorst, Richard J. Woodman, Kevin Murray, Kevin Croft, Oliver Neubauer, Jonathan M. Hodgson, Catherine P. Bondonno

Research outputs 2022 to 2026

Dietary nitrate, found predominantly in green leafy vegetables and other vegetables such as radish, celery, and beetroot, has been shown to beneficially modulate inflammatory processes and immune cell function in animals and healthy individuals. The impact of increased nitrate intake on soluble inflammatory mediators in individuals with hypertension is unclear. We assessed whether the daily consumption of dietary nitrate via beetroot juice for 1-week lowered levels of circulating inflammatory markers in men and women with treated hypertension. Twenty-seven male and female participants were recruited to a randomized, placebo-controlled, double-blind crossover trial. The effects of 1-week intake of nitrate-rich beetroot juice …

Coarse-Grained Modeling Studies Of Entangled Semiflexible Polymers: Melts, Glasses, And Granular Media, Joseph Fox D. Dietz

USF Tampa Graduate Theses and Dissertations

This dissertation is devoted to the computational study of model semiflexible polymers using a coarse-grained bead-spring approach and molecular dynamics (MD) simulations. Much of the work presented here is motivated by the need to derive predictive models for describing polymeric materials’ macroscopic mechanical response from the underlying local structure or local chain parameters. This dissertation describes polymeric materials in the context of granular media, melts, and glasses with a focus on relating characteristics such as chain stiffness and local structure to systems’ solidification, rheology, and fracture mechanisms.

Chain stiffness κ and structural properties like chains’ characteristic bond angle θ0 are …

Do Sociability Expectancies Moderate Social Anxiety Predicting Alcohol Consumption Following A Social Stressor Speech Task, Jacob A. Levine

USF Tampa Graduate Theses and Dissertations

Alcohol use disorder (AUD) and social anxiety disorder (SAD) are two of the most common and chronic psychiatric conditions in the United States. Research indicates individuals with SAD are more likely to meet lifetime criteria for AUD and experience greater AUD symptomatology and severity. Theories explaining this connection are limited, with most built upon tension reduction principles not specific to SAD; however, a recent biopsychosocial model focuses on factors specific to SAD, such as drinking to cope with states of high negative affectivity and arousal. Despite high rates of comorbidity, and more severe AUD presentation, the literature is mixed regarding …

African American Males' Perception Of Factors That Contribute To Success In Higher Education, Gary D. Oliver

USF Tampa Graduate Theses and Dissertations

Over the past decades, many studies have concluded that African American students' college completion rate and success lag far behind other students attending college in the United States (The JBHE Foundation, Inc., 2006). More specifically, these studies have confirmed that African American male students' success rates remain disproportionally low compared to other ethnic male groups. Unfortunately, few notable studies identifying African American males achieving higher education or completing their academic pursuits have been presented as part of the Black male student narrative.

This study aimed to understand better the resources and experiences that positively affect African American males who completed …

Study-Aid Books, Workbooks, And It Equipment As New Materials For School Students In Japanese Public Libraries, Keita Tsuji

Jurnal Ilmu Informasi, Perpustakaan, dan Kearsipan

Japan is no longer a rich country. The poverty rate for “a single adult household with at least one child” is the third highest among the 44 countries of OECD. Public libraries should provide study-aid books, workbooks, and IT equipment to poor students. Based of this idea, we first identified 129 study-aid books and workbooks for junior high and high school students. Next, we investigated whether public libraries of all 1,392 Japanese local governments held them. Then, we asked 631 students whether they wanted public libraries to hold the books and IT equipment such as Nintendo Switch and iPad. Furthermore, …

The Development Of Project Based Learning Model Based On Local Wisdom, Tri Kuat, I Ketut Yudiana, A. Shah

Jurnal Pendidikan: Teori, Penelitian, dan Pengembangan

This study aimed to analyze the implementation of Project Based Learning (PjBL) on Creative Products and Entrepreneurship subject in SMK, develop PjBL based on local wisdom in Creative Products and Entrepreneurship subject, and analyze the effectiveness of developed PjBL in Creative Products and Entrepreneurship. This research design was R&D. PjBL development used the ADDIE model. The research location is at SMK Bima Sakti Batanghari Nuban class XI TP totaling 29 students. Data were obtained through interview and questionnaires. The current PjBL result showed ineffectiveness to be applied. Then, the development of PjBL based on local wisdom showed the significant feasibility …

Naphthoquinones Oxidize H2s To Polysulfides And Thiosulfate, Implications For Therapeutic Applications, Kenneth R Olson, Kasey J Clear, Paul J Derry, Yan Gao, Zhilin Ma, Nathaniel M Cieplik, Alyssa Fiume, Dominic J Gaziano, Stephen M Kasko, Kathleen Narloch, Cecilia L Velander, Ifeyinwa Nwebube, Collin J Pallissery, Ella Pfaff, Brian P Villa, Thomas A Kent, Gang Wu, Karl D Straub

Faculty, Staff and Student Publications

1,4-Napththoquinones (NQs) are clinically relevant therapeutics that affect cell function through production of reactive oxygen species (ROS) and formation of adducts with regulatory protein thiols. Reactive sulfur species (RSS) are chemically and biologically similar to ROS and here we examine RSS production by NQ oxidation of hydrogen sulfide (H2S) using RSS-specific fluorophores, liquid chromatography-mass spectrometry, UV-Vis absorption spectrometry, oxygen-sensitive optodes, thiosulfate-specific nanoparticles, HPLC-monobromobimane derivatization, and ion chromatographic assays. We show that NQs, catalytically oxidize H2S to per- and polysulfides (H2Sn, n = 2−6), thiosulfate, sulfite and sulfate in reactions that consume oxygen and are accelerated by superoxide dismutase (SOD) and …

Dnaja1- And Conformational Mutant P53-Dependent Inhibition Of Cancer Cell Migration By A Novel Compound Identified Through A Virtual Screen., Shigeto Nishikawa, Atsushi Kaida, Alejandro Parrales, Atul Ranjan, Mohamed A.A. Alalem, Hongyi Ren, Frank J. Schoenen, David K. Johnson, Tomoo Iwakuma

Manuscripts, Articles, Book Chapters and Other Papers

Cancers are frequently addicted to oncogenic missense mutant p53 (mutp53). DNAJA1, a member of heat shock protein 40 (HSP40), also known as J-domain proteins (JDPs), plays a crucial role in the stabilization and oncogenic activity of misfolded or conformational mutp53 by binding to and preventing mutp53 from proteasomal degradation. However, strategies to deplete mutp53 are not well-established, and no HSP40/JDPs inhibitors are clinically available. To identify compounds that bind to DNAJA1 and induce mutp53 degradation, we performed an in silico docking study of ~10 million of compounds from the ZINC database for the J-domain of DNAJA1. A compound 7-3 was …

A Machine Learning-Based Method For Automatically Identifying Novel Cells In Annotating Single-Cell Rna-Seq Data, Ziyi Li, Yizhuo Wang, Irene Ganan-Gomez, Simona Colla, Kim-Anh Do

Faculty, Staff and Student Publications

MOTIVATION: Single-cell RNA sequencing (scRNA-seq) has been widely used to decompose complex tissues into functionally distinct cell types. The first and usually the most important step of scRNA-seq data analysis is to accurately annotate the cell labels. In recent years, many supervised annotation methods have been developed and shown to be more convenient and accurate than unsupervised cell clustering. One challenge faced by all the supervised annotation methods is the identification of the novel cell type, which is defined as the cell type that is not present in the training data, only exists in the testing data. Existing methods usually …

Standards In Semen Examination: Publishing Reproducible And Reliable Data Based On High-Quality Methodology, Lars Björndahl, Christopher L R Barratt, David Mortimer, Ashok Agarwal, Robert J Aitken, Juan G Alvarez, Natalie Aneck-Hahn, Stefan Arver, Elisabetta Baldi, Lluís Bassas, Florence Boitrelle, Riana Bornman, Douglas T Carrell, José A Castilla, Gerardo Cerezo Parra, Jerome H Check, Patricia S Cuasnicu, Sally Perreault Darney, Christiaan De Jager, Christopher J De Jonge, Joël R Drevet, Erma Z Drobnis, Stefan S Du Plessis, Michael L Eisenberg, Sandro C Esteves, Evangelini A Evgeni, Alberto Ferlin, Nicolas Garrido, Aleksander Giwercman, Ilse G F Goovaerts, Trine B Haugen, Ralf Henkel, Lars Henningsohn, Marie-Claude Hofmann, James M Hotaling, Piotr Jedrzejczak, Pierre Jouannet, Niels Jørgensen, Jackson C Kirkman Brown, Csilla Krausz, Maciej Kurpisz, Ulrik Kvist, Dolores J Lamb, Hagai Levine, Kate L Loveland, Robert I Mclachlan, Ali Mahran, Liana Maree, Sarah Martins Da Silva, Michael T Mbizvo, Andreas Meinhardt, Roelof Menkveld, Sharon T Mortimer, Sergey Moskovtsev, Charles H Muller, Maria José Munuce, Monica Muratori, Craig Niederberger, Cristian O'Flaherty, Rafael Oliva, Willem Ombelet, Allan A Pacey, Michael A Palladino, Ranjith Ramasamy, Liliana Ramos, Nathalie Rives, Eduardo Rs Roldan, Susan Rothmann, Denny Sakkas, Andrea Salonia, Maria Cristina Sánchez-Pozo, Rosanna Sapiro, Stefan Schlatt, Peter N Schlegel, Hans-Christian Schuppe, Rupin Shah, Niels E Skakkebæk, Katja Teerds, Igor Toskin, Herman Tournaye, Paul J Turek, Gerhard Van Der Horst, Monica Vazquez-Levin, Christina Wang, Alex Wetzels, Theodosia Zeginiadou, Armand Zini

Faculty, Staff and Student Publications

Biomedical science is rapidly developing in terms of more transparency, openness and reproducibility of scientific publications. This is even more important for all studies that are based on results from basic semen examination. Recently two concordant documents have been published: the 6th edition of the WHO Laboratory Manual for the Examination and Processing of Human Semen, and the International Standard ISO 23162:2021. With these tools, we propose that authors should be instructed to follow these laboratory methods in order to publish studies in peer-reviewed journals, preferable by using a checklist as suggested in an Appendix to this article.

Three Generations Later; Examining Transnationalism, Cultural Preservation, And Transgenerational Trauma In United States Indo Population, Jamie D. Stern

Wacana, Journal of the Humanities of Indonesia

This paper examines the relationship between transnationalism, cultural preservation, and transgenerational trauma in the United States (US) Indo population. The information being analysed was compiled by the author from two separate surveys which took place between 2012 and 2021. This data was initially intended to act as a census for the scattered US Indo community however the salient information necessitated that the census be ongoing and that another survey be developed to measure effects of lingering trauma which has been passed down generationally. The two surveys invited Indos from around the globe to participate in data collection, which led to …

Genetic Testing To Inform Epilepsy Treatment Management From An International Study Of Clinical Practice, Dianalee Mcknight, Ana Morales, Kathryn E. Hatchell, Sara L. Bristow, Joshua L. Bonkowsky, Michael Scott Perry, Anne T. Berg, Felippe Borlot, Edward D. Esplin, Chad Moretz, Katie Angione, Loreto Ríos-Pohl, Robert L. Nussbaum, Swaroop Aradhya, Chad R. Haldeman-Englert, Rebecca J. Levy, Venu G. Parachuri, Guillermo Lay-Son, David J. Dávila-Ortiz De Montellano, Miguel Angel Ramirez-Garcia, Edmar O. Benítez Alonso, Julie Ziobro, Adela Chirita-Emandi, Temis M. Felix, Dianne Kulasa-Luke, Andre Megarbane, Shefali Karkare, Sarah L. Chagnon, Jennifer B. Humberson, Melissa J. Assaf, Sebastian Silva, Katherine Zarroli, Oksana Boyarchuk, Gary R. Nelson, Rachel Palmquist, Katherine C. Hammond, Sean T. Hwang, Susan B. Boutlier, Melinda Nolan, Kaitlin Y. Batley, Devraj Chavda, Carlos Alberto Reyes-Silva, Oleksandr Miroshnikov, Britton Zuccarelli, Louise Amlie-Wolf, James W. Wheless, Syndi Seinfeld, Manoj Kanhangad, Jeremy L. Freeman, Susana Monroy-Santoyo, Natalia Rodriguez-Vazquez, Monique M. Ryan, Michelle Machie, Patricio Guerra, Muhammad Jawad Hassan, Meghan S. Candee, Caleb P. Bupp, Kristen L. Park, Eric Muller, Pamela Lupo, Robert C. Pedersen, Amir M. Arain, Andrea Murphy, Krista Schatz, Weiyi Mu, Paige M. Kalika, Lautaro Plaza, Marissa A. Kellogg, Evelyn G. Lora, Robert P. Carson, Victoria Svystilnyk, Viviana Venegas, Rebecca R. Luke, Huiyuan Jiang, Tetiana Stetsenko, Milagros M. Dueñas-Roque, Joseph Trasmonte, Rebecca J. Burke, Anna C. E. Hurst, Douglas M. Smith, Lauren J. Massingham, Laura Pisani, Carrie E. Costin, Betsy Ostrander, Francis M. Filloux, Amitha L. Ananth, Ismail S. Mohamed, Alla Nechai, Jasmin M. Dao, Michael C. Fahey, Ermal Aliu, Stephen Falchek, Craig A. Press, Lauren Treat, Krista Eschbach, Angela Starks, Ryan Kammeyer, Joshua J. Bear, Mona Jacobson, Veronika Chernuha, Bailey Meibos, Kristen Wong, Matthew T. Sweney, A. Chris Espinoza, Colin B. Van Orman, Arie Weinstock, Ashutosh Kumar, Claudia Soler-Alfonso, Danielle A. Nolan, Muhammad Raza, Miguel David Rojas Carrion, Geetha Chari, Eric D. Marsh, Yael Shiloh-Malawsky, Sumit Parikh, Ernesto Gonzalez-Giraldo, Stephen Fulton, Yoshimi Sogawa, Kaitlyn Burns, Myroslava Malets, Johnny David Montiel Blanco, Christa W. Habela, Carey A. Wilson, Guillermo G. Guzmán, Mariia Pavliuk

Department of Pediatrics Faculty Papers

IMPORTANCE: It is currently unknown how often and in which ways a genetic diagnosis given to a patient with epilepsy is associated with clinical management and outcomes.

OBJECTIVE: To evaluate how genetic diagnoses in patients with epilepsy are associated with clinical management and outcomes.

DESIGN, SETTING, AND PARTICIPANTS: This was a retrospective cross-sectional study of patients referred for multigene panel testing between March 18, 2016, and August 3, 2020, with outcomes reported between May and November 2020. The study setting included a commercial genetic testing laboratory and multicenter clinical practices. Patients with epilepsy, regardless of sociodemographic features, who received a …

The Risks Of Birth Defects And Childhood Cancer With Conception By Assisted Reproductive Technology, Barbara Luke, Morton B Brown, Ethan Wantman, Maria J Schymura, Marilyn L Browne, Sarah C Fisher, Nina E Forestieri, Chandrika Rao, Hazel B Nichols, Mahsa M Yazdy, Susan T Gershman, Caitlin R Sacha, Melanie Williams, Mary K Ethen, Mark A Canfield, Kevin J Doody, Michael L Eisenberg, Valerie L Baker, Carrie Williams, Alastair G Sutcliffe, Melissa A Richard, Philip J Lupo

Center for Medical Ethics and Health Policy Staff Publications

Study question: Is there an association between fertility status, method of conception and the risks of birth defects and childhood cancer?

Summary answer: The risk of childhood cancer had two independent components: (i) method of conception and (ii) presence, type and number of birth defects.

What is known already: The rarity of the co-occurrence of birth defects, cancer and ART makes studying their association challenging. Prior studies have indicated that infertility and ART are associated with an increased risk of birth defects or cancer but have been limited by small sample size and inadequate statistical power, failure to adjust for …

Steroid Receptor Coactivator-3 Inhibition Generates Breast Cancer Antitumor Immune Microenvironment, Sang Jun Han, Nuri Sung, Jin Wang, Bert W O'Malley, David M Lonard

Faculty, Staff and Students Publications

BACKGROUND: The tumor immune microenvironment (TIME) generated by cancer-infiltrating immune cells has a crucial role in promoting or suppressing breast cancer progression. However, whether the steroid receptor coactivator-3 (SRC-3) modulates TIME to progress breast cancer is unclear. Therefore, the present study evaluates whether SRC-3 generates a tumor-promoting TIME in breast tumors using a syngeneic immune-intact mouse model of breast cancer.

METHODS: We employed E0771 and 4T1 breast cancer in immune-intact syngeneic female C57BL/6 and BALB/c mice, respectively. SI-2, a specific small-molecule inhibitor of SRC-3, was administered daily (2.5 mg/kg) to E0771 and 4T1 breast tumor-bearing immune-intact mice. In addition, SRC-3 …

Identification Of Novel Genes And Proteoforms In Angiostrongylus Costaricensis Through A Proteogenomic Approach, Esdras Matheus Gomes Da Silva, Karina Mastropasqua Rebello, Young-Jun Choi, Vitor Gregorio, Alexandre Rossi Paschoal, Makedonka Mitreva, James H Mckerrow, Ana Gisele Da Costa Neves-Ferreira, Fabio Passetti

2020-Current year OA Pubs

RNA sequencing (RNA-Seq) and mass-spectrometry-based proteomics data are often integrated in proteogenomic studies to assist in the prediction of eukaryote genome features, such as genes, splicing, single-nucleotide (SNVs), and single-amino-acid variants (SAAVs). Most genomes of parasite nematodes are draft versions that lack transcript- and protein-level information and whose gene annotations rely only on computational predictions.

The Effects Of Teaching Undergraduate Freshmen Biology Courses In Spanish And English, Angela M. Chapman, Amy A. Weimer, Mirayda Torres-Avila, Cristina Trejo, Alexis Racelis

Teaching and Learning Faculty Publications

This study examines the attitudes and experiences of bilingual learners across two instructional types, identifying how the language of instruction affects the context of learning, and how the experience of the learners differs. Participants included 269 predominantly Hispanic undergraduate students in a general biology course attending a Hispanic Serving Institution in a bilingual community along the US-Mexico border. A bilingual faculty member, who recognizes the sociocultural and contextual factors that affect student learning and adopts a teaching philosophy founded in Culturally Responsive Practices (CRP) and valuing students’ Funds of Knowledge taught the class. This study utilized a mixed method design …

Microrna Content Of Ewing Sarcoma Derived Extracellular Vesicles Leads To Biomarker Potential And Identification Of A Previously Undocumented Ews-Fli1 Translocation., Jennifer Crow, Glenson Samuel, Emily G. Farrow, Margaret Gibson, Jeffrey J. Johnston, Erin M. Guest, Neil Miller, Dong Pei, Devin Koestler, Harsh Pathak, Xiaobo Liang, Cooper Mangels, Andrew K. Godwin

Manuscripts, Articles, Book Chapters and Other Papers

Objective: Ewing Sarcoma Family of Tumors (ESFT) are a highly aggressive pediatric bone and soft tissue malignancy with poor outcomes in the refractory and recurrent setting. Over 90% of Ewing Sarcoma (ES) tumors are driven by the pathognomonic EWS-ETS chimeric transcripts and their corresponding oncoproteins. It has been suggested that the EWS-ETS oncogenic action can mediate microRNA (miRNA) processing. Importantly, small extracellular vesicles (sEVs), including those frequently referred to as exosomes have been shown to be highly enriched with tumor-derived small RNAs such as miRNAs. We hypothesized that ESFT-specific sEVs are enriched with certain miRNAs which could be utilized toward …

Problems Facing Dentists In The North Region In Jordan, Zuhair Al-Sharae

An-Najah University Journal for Research - B (Humanities)

This study aims at identifying the problems facing dentists in the North Region in Jordan, Where the population of the study consisted of all dentists working in health centers located in the North Region, which fall within the range of the governorates (Ajloun, Irbid, Jerash, and Mafraq), and their number was (171) dentists, and the study sample consisted of (154) dentists, who were selected from the study population. The study was implemented during the period from (1/25/2020 to 07/30/2020). The study relied on the descriptive approach, and a questionnaire was built to collect data, containing three fields: (personal and social …

Environmental Influence On Stickleback Fish Phenotype, Alaina A. Young

RURALS: Review of Undergraduate Research in Agricultural and Life Sciences

Abstract

Sticklebacks have grown to be a model organism in the last few decades because they have undergone a rapid adaptive radiation event. Portions of the original marine population have migrated to isolated freshwater ecosystems and their fundamental niche has expanded. Variation among select phenotypic traits is a direct result of selective pressures imposed by new environment types. Lateral plates have been the most widely analyzed trait, it is hypothesized that great variation in plate quantity has resulted from expansion events. Lateral plates are pieces of an exoskeleton in addition to the already established endoskeleton. This study aims to assess …

Antiproliferative Effects Of Some Medicinal Plants On Colorectal Cancer: A Mini Review, Jamilah Borjac

BAU Journal - Health and Wellbeing

Colorectal cancer (CRC) is one of the highly prevalent and deadly cancers worldwide. Surgery, chemotherapy and radiotherapy are the conventional treatment modalities for CRC; however, they cause adverse side effects and can be associated with cancer resistance and relapse. Currently, traditional herbal medicine is becoming increasingly studied and used in combination with conventional treatments in CRC. Various medicinal plants have shown promising anticancer effects against CRC concomitant with negligible side effects. For example, Annona muricata (soursop), Chenopodium quinoa (quinoa), Matricaria chamomilla (chamomile), and Moringa oleifera (moringa) have shown remarkable antiproliferative effects against CRC both in vitro and in vivo. Therefore, …