Digital Commons Network^™

Enabling The Human Perception Of A Working Camera In Web Conferences Via Its Movement, Anish Shrestha

LSU Master's Theses

In recent years, video conferencing has seen a significant increase in its usage due to the COVID-19 pandemic. When casting user’s video to other participants, the videoconference applications (e.g. Zoom, FaceTime, Skype, etc.) mainly leverage 1) webcam’s LED-light indicator, 2) user’s video feedback in the software and 3) the software’s video on/off icons to remind the user whether the camera is being used. However, these methods all impose the responsibility on the user itself to check the camera status, and there have been numerous cases reported when users expose their privacy inadvertently due to not realizing that their camera is …

Metformin Increases Natural Killer Cell Functions In Head And Neck Squamous Cell Carcinoma Through Cxcl1 Inhibition, Mckenzie Crist, Benyamin Yaniv, Sarah Palackdharry, Maria A. Lehn, Mario Medvedovic, Timothy Stone, Shuchi Gulati, Vidhya Karivedu, Michael Borchers, Bethany Fuhrman, Audrey Crago, Joseph Curry, Ubaldo Martinez-Outschoorn, Vinita Takiar, Trisha M. Wise-Draper

Department of Otolaryngology - Head and Neck Surgery Faculty Papers

BACKGROUND: Metformin slows tumor growth and progression in vitro, and in combination with chemoradiotherapy, resulted in high overall survival in patients with head and neck cancer squamous cell carcinoma (HNSCC) in our phase 1 clinical trial (NCT02325401). Metformin is also postulated to activate an antitumor immune response. Here, we investigate immunologic effects of metformin on natural killer (NK) and natural killer T cells, including results from two phase I open-label studies in patients with HNSCC treated with metformin (NCT02325401, NCT02083692).

METHODS: Peripheral blood was collected before and after metformin treatment or from newly diagnosed patients with HNSCC. Peripheral immune cell …

Building And Supporting A Research To Publication Pipeline, Sowmya Anjur, Jean Bigger, Joyce Symoniak

Publications & Research

Participants in this session will learn how IMSA is generating and disseminating scholarship and incorporating students into its research to publication pipeline.

We will also be discussing the benefits of including our student’s best work in DigitalCommons; students having the opportunity to own a publication before leaving high school and inspiring other students to do the same, witnessing their own growth in critical thinking and written communication skills, developing student portfolios, and graduating with an understanding of the importance and benefit of being connected to a global community of scholars.

The Open Educational Resources (OERs) being shared through IMSA’s institutional …

Complete Genome Sequences Of Genamy16 And Novasharks, Two Gordonia Rubripertincta Bacteriophages Isolated From Soil In Southeastern Florida, Julie Torruellas Garcia, Sarah Ballarin, Neel Balusa, Melissa Bell, Samia Caballero, Joshua Chan, Maria Farez, Ashley J. Guillen-Tapia, Kristin Parent, Nashrah Pierre-Louis, Victoria Polishuk, Bhavya Soni, Sundharraman Subramanian, Katie E. Crump

Biology Faculty Articles

We report on two actinobacteriophages, Genamy16 and NovaSharks, that were isolated from soil in Florida using Gordonia rubripertincta NRRL B-16540. The genomes of both phages are ~65,000 bp, with similar GC contents, and, based on gene content similarity to phages in the Actinobacteriophage Database, were assigned to phage cluster DV.

Population Structure, Diet, And Bioenergetics Of Introduced Smallmouth Bass In An Intermountain West Reservoir, Skylar L. Wolf, Natalie Boren, Benjamin Vasquez, Jack Dudding, Robert Shields

Western North American Naturalist

Smallmouth Bass Micropterus dolomieu is a recreationally important sport fish throughout much of North America, but population metrics are lacking in the Intermountain West, where the species is not native and where its performance may differ from other geographic portions of its range. We characterized population structure and condition, growth, and the feeding habitats and bioenergetics of a self-sustaining Smallmouth Bass population in Starvation Reservoir, located in northeast Utah. In this reservoir, Smallmouth Bass may experience environmental conditions (e.g., shorter growing season and greater water-level fluctuation) that are uncommon to other portions of its range. We found growth rates to …

November 2022 Faculty Senate Packet, University Of Nebraska At Kearney Faculty Senate

Faculty Senate Packets

No abstract provided.

Racial/Ethnic Disparities Of Cancer, Metabolic Syndrome, And Lifestyle Behaviors In People Under 50: A Cross-Sectional Study Of Data From The National Health And Nutrition Examination Survey, Lin Zhu, Areebah Rahman, Ming-Chin Yeh, Grace X. Ma

Publications and Research

Introduction: Recent epidemiological studies have suggested a trend of increasing preva- lence of metabolic syndrome (MetS) and certain types of cancer among adults under age 50. How MetS is associated with cancer in adults under the age of 50, however, remains unclear. Furthermore, it remains unknown whether associations between MetS and cancer vary by racial/ethnic group and whether modifiable lifestyle factors influence MetS–cancer relationships. Methods: We used data from the 2011–2018 National Health and Nutrition Examination Survey (NHANES) to define a case-control sample to examine potential racial/ethnic disparities associated with MetS and cancer of any type. We used a chi-square …

Characterization Of Bcma Expression In Circulating Rare Single Cells Of Patients With Plasma Cell Neoplasms, Libere J Ndacayisaba, Kate E Rappard, Stephanie N Shishido, Sonia M Setayesh, Guilin Tang, Pei Lin, Nicholas Matsumoto, Ching-Ju Hsu, Rafael Nevarez, Carmen Ruiz Velasco, Amin Naghdloo, Eric Yang, Kevin Kelly, James Hicks, Jeremy Mason, Robert Z Orlowski, Elisabet E Manasanch, Peter Kuhn

Faculty, Staff and Student Publications

B-cell maturation antigen (BCMA), a key regulator of B-cell proliferation and survival, is highly expressed in almost all cases of plasma cell neoplasms and B-lymphoproliferative malignancies. BCMA is a robust biomarker of plasma cells and a therapeutic target with substantial clinical significance. However, the expression of BCMA in circulating tumor cells of patients with hematological malignancies has not been validated for the detection of circulating plasma and B cells. The application of BCMA as a biomarker in single-cell detection and profiling of circulating tumor cells in patients' blood could enable early disease profiling and therapy response monitoring. Here, we report …

The Cowl - V. 87 N. 6 - November 3, 2022

The Cowl

The Cowl - student newspaper of Providence College. Vol. 87 No. 6 - November 3, 2022. 20 pages.

Exceptional Larval Morphology Of Nine Species Of The Anastrepha Mucronota Species Group (Diptera: Tephritidae), Erick J. Rodriguez, Gary J. Steck, Matthew R. Moore, Allen L. Norrbom, Jessica Diaz, Louis A. Somma, Raul Ruiz-Arce, Bruce D. Sutton, Norma Nolazco, Alies Muller, Marc A. Branham

Papers in Evolution

Anastrepha is the most diverse and economically important genus of Tephritidae in the American tropics and subtropics. The striking morphology of the third instars of Anastrepha caballeroi Norrbom, Anastrepha crebra Stone, Anastrepha haplacantha Norrbom & Korytkowski, Anastrepha korytkowskii Norrbom, Anastrepha nolazcoae Norrbom & Korytkowski, and three newly discovered and as yet formally unnamed species (Anastrepha sp. Peru-82, Anastrepha sp. nr. protuberans, and Anastrepha sp. Sur-16), and the more typical morphology of Anastrepha aphelocentema Stone, are described using light and scanning electron microscopy. To contribute to a better understanding of the interspecific and intraspecific variation among species in the mucronota …

Correctness And Response Time Distributions In The Memtrax Continuous Recognition Task: Analysis Of Strategies And A Reverse-Exponential Model, J. Wesson Ashford, James O. Clifford, Sulekha Anand, Michael F. Bergeron, Curtis B. Ashford, Peter J. Bayley

Faculty Research, Scholarly, and Creative Activity

A critical issue in addressing medical conditions is measurement. Memory measurement is difficult, especially episodic memory, which is disrupted by many conditions. On-line computer testing can precisely measure and assess several memory functions. This study analyzed memory performances from a large group of anonymous, on-line participants using a continuous recognition task (CRT) implemented at https://memtrax.com. These analyses estimated ranges of acceptable performance and average response time (RT). For 344,165 presumed unique individuals completing the CRT a total of 602,272 times, data were stored on a server, including each correct response (HIT), Correct Rejection, and RT to the thousandth of a …

The Public Perception Of The #Geneeditedbabies Event Across Multiple Social Media Platforms: Observational Study, Ellen W. Clayton, Congning Ni, Et Al.

Vanderbilt Law School Faculty Publications

In November 2018, a Chinese researcher reported that his team had applied clustered regularly interspaced palindromic repeats or associated protein 9 to delete the gene C-C chemokine receptor type 5 from embryos and claimed that the 2 newborns would have lifetime immunity from HIV infection, an event referred to as #GeneEditedBabies on social media platforms. Although this event stirred a worldwide debate on ethical and legal issues regarding clinical trials with embryonic gene sequences, the focus has mainly been on academics and professionals. However, how the public, especially stratified by geographic region and culture, reacted to these issues is not …

The Montclarion, November 03, 2022, The Montclarion

The Montclarion

Student Newspaper of Montclair State University

Deepdemod: Bpsk Demodulation Using Deep Learning Over Software-Defined Radio, Arhum Ahmad, Satyam Agarwal, Sam Darshi, Sumit Chakravarty

Open Access Publishing Fund Collection

In wireless communication, signal demodulation under non-ideal conditions is one of the important research topic. In this paper, a novel non-coherent binary phase shift keying demodulator based on deep neural network, namely DeepDeMod, is proposed. The proposed scheme makes use of neural network to decode the symbols from the received sampled signal. The proposed scheme is developed to demodulate signal under fading channel with additive white Gaussian noise along with hardware imperfections, such as phase and frequency offset. The time varying nature of hardware imperfections and channel poses a additional challenge in signal demodulation. In order to address this issue, …

Sexual Dysfunction And Sexual Distress In Lymphoma Patients: A Mixed Methods Pilot Study, Dorothie S. Durosier Mertilus

USF Tampa Graduate Theses and Dissertations

Lymphoma, especially non-Hodgkin lymphoma (NHL), is among the most common categories of cancer in the United States (National Cancer Institute [NCI], 2019). The survival rate for lymphoma has significantly improved over the last few decades due to advances in therapy. However, despite these advances, lymphoma patients experience many negative consequences of cancer treatment, including sexual dysfunction (NCI, 2021b). The purpose of this mixed methods pilot study was to explore the presence and experiences of sexual dysfunction and related sexual distress in both male and female lymphoma patients during cancer treatment. A concurrent triangulated design was used to: 1) evaluate the …

A Comprehensive Review On Nutraceuticals: Therapy Support And Formulation Challenges, Vivek Puri, Manju Nagpal, Inderbir Singh, Manjinder Singh, Gitika Arora Dhingra, Kampanart Huanbutta, Divya Dheer, Ameya Sharma, Tanikan Sangnim

Faculty, Staff and Student Publications

Nutraceuticals are the nourishing components (hybrid of nutrition and pharmaceuticals) that are biologically active and possess capability for maintaining optimal health and benefits. These products play a significant role in human health care and its endurance, most importantly for the future therapeutic development. Nutraceuticals have received recognition due to their nutritional benefits along with therapeutic effects and safety profile. Nutraceuticals are globally growing in the field of services such as health care promotion, disease reduction, etc. Various drug nutraceutical interactions have also been elaborated with various examples in this review. Several patents on nutraceuticals in agricultural applications and in various …

Dll3 As An Emerging Target For The Treatment Of Neuroendocrine Neoplasms, James Yao, Emily Bergsland, Rahul Aggarwal, Ana Aparicio, Himisha Beltran, Judy S Crabtree, Christine L Hann, Toni Ibrahim, Lauren A Byers, Hironobu Sasano, John Umejiego, Marianne Pavel

Faculty, Staff and Student Publications

INTRODUCTION: Neuroendocrine neoplasms (NEN) are heterogeneous malignancies that can arise at almost any anatomical site and are classified as biologically distinct well-differentiated neuroendocrine tumors (NET) and poorly differentiated neuroendocrine carcinomas (NEC). Current systemic therapies for advanced disease, including targeted therapies, chemotherapy, and immunotherapy, are associated with limited duration of response. New therapeutic targets are needed. One promising target is delta-like ligand 3 (DLL3), an inhibitory ligand of the Notch receptor whose overexpression on the surface of NEN is associated with tumorigenesis.

METHODS: This article is a narrative review that highlights the role of DLL3 in NEN progression and prognosis, the …

Epacadostat Plus Pembrolizumab And Chemotherapy For Advanced Solid Tumors: Results From The Phase I/Ii Echo-207/Keynote-723 Study, John D Powderly, Samuel J Klempner, Aung Naing, Johanna Bendell, Ignacio Garrido-Laguna, Daniel V T Catenacci, Matthew H Taylor, James J Lee, Fred Zheng, Feng Zhou, Xiaohua Gong, Hema Gowda, Gregory L Beatty

Faculty, Staff and Student Publications

Background: Epacadostat, an oral, selective inhibitor of IDO1, has shown activity when administered with pembrolizumab. We evaluated the addition of chemotherapy to epacadostat and pembrolizumab in patients with advanced or metastatic solid tumors. One proposed mechanism of resistance to PD-1 checkpoint inhibition is through immunosuppression mediated by L-kynurenine. IDO1, indoleamine-2,3-dioxygenase 1 is the rate-limiting enzyme catalyzing the conversion of L-tryptophan to L-kynurenine. If IDO1 is a mechanism of tumor escape from checkpoint inhibition, then addition of an IDO1 inhibitor with a PD-1 checkpoint inhibitor could enable tumor response to immunotherapy.

Methods: Patients received one of 7 tumor-appropriate chemotherapy regimens. Pembrolizumab …

Zebras Of All Stripes Repel Biting Flies At Close Range, Kaia J. Tombak, Andrew S. Gersick, Lily V. Reisinger, Brenda Larison, Daniel I. Rubenstein

Publications and Research

The best-supported hypothesis for why zebras have stripes is that stripes repel biting flies. While this effect is well-established, the mechanism behind it remains elusive. Myriad hypotheses have been suggested, but few experiments have helped narrow the field of possible explanations. In addition, the complex visual features of real zebra pelage and the natural range of stripe widths have been largely left out of experimental designs. In paired-choice field experiments in a Kenyan savannah, we found that hungry Stomoxys flies released in an enclosure strongly preferred to land on uniform tan impala pelts over striped zebra pelts but exhibited no …

Effect Of Canopy Competition On Tree Growth And Development In Pine Hardwood Mixtures, Jacob Alexander Olichney

LSU Master's Theses

Mixed species forests may benefit from the reduction in intraspecific competition, although the benefit of species mixing has been shown to vary depending on mixture composition and environmental conditions. This study sought to test the effect of species composition in mixed forest stands on canopy development and growth of loblolly pine (Pinus taeda), cherrybark oak (Quercus pagoda), and sweetgum (Liquidambar styraciflua). Even-aged, grid planted monoculture and mixed species forest plots were established with hardwood monoculture plots at a 741 Trees Per Hectare (TPH), and pine monoculture and mixed species plots established at 1482 TPH. …

Esterase Mediated Insecticide Resistance In The Southern House Mosquito, Culex Quinquefasciatus, Vivek Pokhrel

LSU Doctoral Dissertations

Much is known about the development of insecticide resistance associated with targeted application against insect populations. However, off-target selection by applications of insecticides in agricultural and residential sites also impacts development of insecticide resistance and is understudied. Similarly, the impact of selecting one life stage of mosquitoes on the insecticide susceptibility of different life stages is largely unknown. The first part of this study shows that susceptibility to chlorantraniliprole, which is applied in rice and sugarcane fields in LA, decreased (5.7 to12-fold) in populations of Culex quinquefasciatus collected from near these fields compared to a reference field strain. In addition, …

Spam Detection Using Machine Learning And Deep Learning, Olubodunde Agboola

LSU Doctoral Dissertations

Text messages are essential these days; however, spam texts have contributed negatively to the success of this communication mode. The compromised authenticity of such messages has given rise to several security breaches. Using spam messages, malicious links have been sent to either harm the system or obtain information detrimental to the user. Spam SMS messages as well as emails have been used as media for attacks such as masquerading and smishing ( a phishing attack through text messaging), and this has threatened both the user and service providers. Therefore, given the waves of attacks, the need to identify and remove …

Sers Platform For Single Fiber Endoscopic Probes, Debsmita Biswas

LSU Doctoral Dissertations

Molecular detection techniques have huge potential in clinical environments. In addition to many other molecular detection techniques, endoscopic Raman spectroscopy has great ability in terms of minimal invasiveness and real-time spectra acquisition. However, Raman Effect is low in sensitivity, limiting the application. Surface-Enhanced Raman Scattering (SERS), addresses this limitation. SERS brings rough nano-metallic surfaces in contact with specimen molecules which enormously enhances Raman signals. This provides Raman spectroscopy with immense capabilities for diverse fields of applications.

Generally, in clinical probe applications, the spectrometer is brought near the target molecules for detection. Typically, optical fibers are used to couple spectrometers to …

From Biowaste To Product: The Functionalization Of Biochar For Agricultural And Environmental Applications, Baoyue Zhou

LSU Doctoral Dissertations

Biochar is a porous carbonated substance that is manufactured through pyrolysis of biomass feedstocks in an oxygen-deficiency environment. The production of biochar from agricultural waste materials provides a potential solution for eliminating pollution while improving carbon sequestration. While biochar is shown to provide multiple benefits to soil health and fertility, its use in environmental remediation has been hampered by its low affinity for hazardous anionic species and the difficulty in isolating from water phase. To overcome these obstacles, various efforts have been made to modify biochar surface chemistry and morphology.

Fe/Mg co-doped biochar composites from sugarcane harvest residue were prepared …

The Role Of Kisspeptins In Trophoblast Cell Dynamics: Comparative Studies Using The Horse And The Preeclamptic-Like Bph/5 Mouse As Animal Models, Viviane Cristine Leite Gomes

LSU Doctoral Dissertations

Kisspeptins, a family of small peptides derived from the Kiss1 gene, have been described in trophoblast cell dynamics, placentation, and pregnancy outcomes. Furthermore, many other physiological functions have been attributed to kisspeptins, including neuroendocrine regulation of puberty and cyclicity, and peripheral and central regulation of metabolism and adipogenesis. Herein, studies were performed in the Blood Pressure High Subline 5 (BPH/5) mouse and the horse to further investigate the role of kisspeptins in pregnancy. The BPH/5 mouse recapitulates the main features of human preeclampsia (PE), a hypertensive disorder of pregnancy associated with maternal and fetal adverse outcomes. BPH/5 phenotypic characteristics include …

November 3, 2022, James Madison University

The Breeze, 2020-

The Breeze is the student newspaper of James Madison University in Harrisonburg, Virginia.

The Childhood Acute Illness And Nutrition (Chain) Network Nested Case-Cohort Study Protocol: A Multi-Omics Approach To Understanding Mortality Among Children In Sub-Saharan Africa And South Asia, James M. Njunge, Kirkby Tickell, Abdoulaye Hama Diallo, Abu Sadat Mohammad Sayeem Bin Shahi, Md Amran Gazi, Ali Faisal Saleem, Zaubina Kazi, Syed Ali, Caroline Tigoi, Ezekiel Mupere

Department of Paediatrics and Child Health

Introduction: Many acutely ill children in low- and middle-income settings have a high risk of mortality both during and after hospitalisation despite guideline-based care. Understanding the biological mechanisms underpinning mortality may suggest optimal pathways to target for interventions to further reduce mortality. The Childhood Acute Illness and Nutrition (CHAIN) Network ( www.chainnnetwork.org) Nested Case-Cohort Study (CNCC) aims to investigate biological mechanisms leading to inpatient and post-discharge mortality through an integrated multi-omic approach.
Methods and analysis; The CNCC comprises a subset of participants from the CHAIN cohort (1278/3101 hospitalised participants, including 350 children who died and 658 survivors, and …

The Student Movement Volume 107 Issue 7: Hot Drinks & Hayrides: Barn Party Comes To Campus, Kavya Mohanram, Anna Pak, Amelia Stefanescu, Solana Campbell, Lily Rodriguez, Hannah Cruse, Nicholas C. Gunn, Alannah Tjhatra, Nora Martin, Terika Williams, Grace No, Valerie Akinyi, Ralph Gifford, Abraham Bravo, Gloria Oh, Melissa Moore

The Student Movement v. 107 (2022-2023)

HUMANS

Meet David Springer: AUGSA President, Interviewed by: Kavya Mohanram

Meet Rock Choi: AUSA Presidential Assistant, Interviewed by: Anna Pak

Women in Stem: Minseo Kang, Interviewed by: Anna Pak

ARTS & ENTERTAINMENT

Creatives on Campus: Passion Through A New Lens, Amelia Stefanescu

Currently..., Solana Campbell

Fatphobic or Sensitive?, Lily Rodriguez

Take 3: Is Love Truly Blind?, Hannah Cruse

NEWS

AUSA & AFIA End Filipino American History Month On A High Note, Nicholas C. Gunn

AUSA Hosts Barn Party, Alannah Tjhatra

Honors Outing to Chicago Shakespeare Theater, Nora Martin

IDEAS

Reader's Digest: Midterm Election, Terika Willliams

The Death of the Rom-Com, …

Phenome-Wide Analysis Of Taiwan Biobank Reveals Novel Glycemia-Related Loci And Genetic Risks For Diabetes, Chia-Jung Lee, Ting-Huei Chen, Aylwin Ming Wee Lim, Chien-Ching Chang, Jia-Jyun Sie, Pei-Lung Chen, Su-Wei Chang, Shang-Jung Wu, Chia-Lin Hsu, Ai-Ru Hsieh, Wei-Shiung Yang, Cathy S J Fann

2020-Current year OA Pubs

To explore the complex genetic architecture of common diseases and traits, we conducted comprehensive PheWAS of ten diseases and 34 quantitative traits in the community-based Taiwan Biobank (TWB). We identified 995 significantly associated loci with 135 novel loci specific to Taiwanese population. Further analyses highlighted the genetic pleiotropy of loci related to complex disease and associated quantitative traits. Extensive analysis on glycaemic phenotypes (T2D, fasting glucose and HbA

Metabolic Pathways Enriched According To Erg Status Are Associated With Biochemical Recurrence In Hispanic/Latino Patients With Prostate Cancer, Natalia L. Acosta-Vega, Rodolfo Varela, Jorge Andrés Mesa, Jone Garai, Melody C. Baddoo, Alberto Gómez-Gutiérrez, Silvia J. Serrano-Gómez, Marcela Nuñez Lemus, Martha Lucía Serrano, Jovanny Zabaleta, Alba L. Combita, María Carolina Sanabria-Salas

School of Medicine Faculty Publications

Background: The role of ERG-status molecular subtyping in prognosis of prostate cancer (PCa) is still under debate. In this study, we identified differentially expressed genes (DEGs) according to ERG-status to explore their enriched pathways and implications in prognosis in Hispanic/Latino PCa patients. Methods: RNA from 78 Hispanic PCa tissues from radical prostatectomies (RP) were used for RNA-sequencing. ERGhigh/ERGlow tumor groups were determined based on the 1.5-fold change median expression in non-tumor samples. DEGs with a False Discovery Rate (FDR) < 0.01 and a fold change >2 were identified between ERGhigh and ERGlow tumors and submitted to enrichment analysis in MetaCore. Survival and association analyses were performed …