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A Framework For Addressing Foster Care Trauma In The Public Education System: Perceptions And Implications, Valerie A. Storey, Fletcher Roschanda

All Faculty and Staff Scholarship

BACKGROUND

It is estimated that approximately 90% of children in foster care have experienced a traumatic event, with nearly half reporting exposure to 4 or more types of traumatic events. Educators must remain alert to indicators suggesting a history of trauma and understand the difficulties foster youth may face regulating their emotions and behavior while in school.

METHODS

A framework for foster youth trauma in the public education system identifies the interplay between macro-level forces, such as federal and state policy, and school and teacher micro-level forces.

RESULTS

The framework highlights the inadequacy of educators in identifying the manifestations of …

Mechanisms Of Recovery: Community Perceptions Of Change And Growth Following Multiple Disasters, Howard Osofsky, Joy Osofsky, Leia Y. Saltzman, Estilla Lightfoot, Jule De King, Tonya C. Hansel

School of Medicine Faculty Publications

Introduction and purpose: The geographic location of the Gulf South leaves communities in continuous threat, response, and recovery disaster cycles. Hurricane Katrina in 2005 provided an opportunity to study disaster mental health. Less than 5 years after the storm, many Hurricane Katrina survivors were impacted again by the Deepwater Horizon Gulf oil spill. Despite adversities impacting Gulf communities, over 90% of participants reported they were resilient. The purpose of this study was to improve the understanding of the mechanisms that contribute to strengths following adversity in communities affected by repeated disasters. Specifically, we focused on survivor perceptions of personal, spiritual, …

Applying Biomimetic Passive Dynamics To A Quadruped Robot Leg, Emma Krnacik

Dissertations and Theses

The study of synthetic nervous systems is an emerging field within biomimetic robotics as an alternative to more classic control techniques. As the modeling of these nervous systems becomes more accurate, it is important to note that the nervous system and physical system co-evolved and continue to operate in an interdependent fashion. Many legged robots, including the existing quadruped in the AARL, have leg systems that may have similar geometrical properties to that of a mammal, but have significantly different dynamic properties. This paper presents a method for designing a limb so that the passive dynamics more accurately represent that …

Hematophagy And Tick-Borne Rickettsial Pathogen Shape The Microbial Community Structure And Predicted Functions Within The Tick Vector, Amblyomma Maculatum., Abdulsalam Adegoke, Deepak Kumar, Khemraj Budachetri, Shahid Karim

Faculty Publications

Background: Ticks are the primary vectors of emerging and resurging pathogens of public health significance worldwide. Analyzing tick bacterial composition, diversity, and functionality across developmental stages and tissues is crucial for designing new strategies to control ticks and prevent tick-borne diseases.

Materials and methods: Here, we explored the microbial communities across the developmental timeline and in different tissues of the Gulf-Coast ticks (Amblyomma maculatum). Using a high-throughput sequencing approach, the influence of blood meal and Rickettsia parkeri, a spotted fever group rickettsiae infection in driving changes in microbiome composition, diversity, and functionality was determined.

Results: This study …

Post-Developmental Plasticity Of The Primary Rod Pathway Allows Restoration Of Visually Guided Behaviors, Yan Cao, Diego Fajardo, Debbie Guerrero-Given, Melanie A Samuel, Toshihisa Ohtsuka, Shannon E Boye, Naomi Kamasawa, Kirill A Martemyanov

Center on Aging Staff Publications

Formation of neural circuits occurs in a programmed fashion, but proper activity in the circuit is essential for refining the organization necessary for driving complex behavioral tasks. In the retina, sensory deprivation during the critical period of development is well known to perturb organization of the visual circuit making the animals unable to use vision for behavior. However, the extent of plasticity, molecular factors involved and malleability of individual channels in the circuit to manipulations outside of the critical period are not well understood. In this study we selectively disconnected and reconnected rod photoreceptors in mature animals after completion of …

Depletion Of Cd206+ M2-Like Macrophages Induces Fibro-Adipogenic Progenitors Activation And Muscle Regeneration, Allah Nawaz, Muhammad Bilal, Shiho Fujisaka, Tomonobu Kado, Muhammad Rahil Aslam, Saeed Ahmed, Keisuke Okabe, Yoshiko Igarashi, Yoshiyuki Watanabe, Takahide Kuwano, Koichi Tsuneyama, Ayumi Nishimura, Yasuhiro Nishida, Seiji Yamamoto, Masakiyo Sasahara, Johji Imura, Hisashi Mori, Martin M Matzuk, Fujimi Kudo, Ichiro Manabe, Akiyoshi Uezumi, Takashi Nakagawa, Yumiko Oishi, Kazuyuki Tobe

Faculty, Staff and Students Publications

Muscle regeneration requires the coordination of muscle stem cells, mesenchymal fibro-adipogenic progenitors (FAPs), and macrophages. How macrophages regulate the paracrine secretion of FAPs during the recovery process remains elusive. Herein, we systemically investigated the communication between CD206+ M2-like macrophages and FAPs during the recovery process using a transgenic mouse model. Depletion of CD206+ M2-like macrophages or deletion of CD206+ M2-like macrophages-specific TGF-β1 gene induces myogenesis and muscle regeneration. We show that depletion of CD206+ M2-like macrophages activates FAPs and activated FAPs secrete follistatin, a promyogenic factor, thereby boosting the recovery process. Conversely, deletion of the FAP-specific follistatin gene results in …

Structural Basis Of Synthetic Agonist Activation Of The Nuclear Receptor Rev-Erb, Meghan H Murray, Aurore Cecile Valfort, Thomas Koelblen, Céline Ronin, Fabrice Ciesielski, Arindam Chatterjee, Giri Babu Veerakanellore, Bahaa Elgendy, John K Walker, Lamees Hegazy, Thomas P Burris

2020-Current year OA Pubs

The nuclear receptor REV-ERB plays an important role in a range of physiological processes. REV-ERB behaves as a ligand-dependent transcriptional repressor and heme has been identified as a physiological agonist. Our current understanding of how ligands bind to and regulate transcriptional repression by REV-ERB is based on the structure of heme bound to REV-ERB. However, porphyrin (heme) analogues have been avoided as a source of synthetic agonists due to the wide range of heme binding proteins and potential pleotropic effects. How non-porphyrin synthetic agonists bind to and regulate REV-ERB has not yet been defined. Here, we characterize a high affinity …

Sub-Recent Microfauna Within Allogenic Sediments At The Bottom Of A Deep Cave, Njemica (Biokovo Mt., Croatia), Tomislav Kurečić, Valentina Hajek Tadesse, Lara Wacha, Marija Horvat, Nina Trinajstić, Ivan Mišur

International Journal of Speleology

Clastic sediments deposited at the bottom of the vertical, nearly 1000 m deep Njemica Cave (Biokovo Mountain, Croatia) were analysed. Owing to the vertical morphology of the cave, the occurrences of clastic sediments are sparse. Small, up to decimetre-thick, undisturbed sediment accumulations situated near the siphon lake revealed interesting palaeontological and mineralogical data. These data are used as a useful proxy for discussing depositional processes, the provenance of the sediments and paleo-habitats of the subterranean fauna.

The sub-recent assemblages of ostracods were discovered within the sediment, and they were shown to be correlative to the known endemic species in the …

Effectiveness Of A Program Based On Stem In Developing Critical Thinking Skills In Mathematics Among Eleventh Grade Scientific Students In Gaza, Mohammed Asqule, Rana Ziada

An-Najah University Journal for Research - B (Humanities)

The study aimed to investigate the effectiveness of a program based on STEM approach in developing critical thinking skills in Mathematics for the students in GAZA. To achieve the study objectives, the researchers adopted the experimental approach. A program based on STEM, teacher guide has been prepared. To verify the effectiveness of the program, the study tool was a critical thinking skills test. This test has undergone pre and post application on a sample consisted of a group of (86) female students selected from Al-Zahraa Secondary School. The study results revealed that there were statistically significant differences at the level …

Saint Jude's, November 20, 2022

Saint Jude's

A newsletter published for Deaf Catholics in Waltham, MA

Saint Jude's Finding Aid

Are We Ovary-Acting? All Visuospatial Abilities May Not Be Equally Affected Throughout The Menstrual Cycle., Caroline G. Haynes, Audrey N. Wade

Science University Research Symposium (SURS)

Are we ovary-acting? All visuospatial abilities may not be equally affected throughout the menstrual cycle.

Department of Psychological Sciences & Neuroscience, Belmont University, Nashville, TN

Visuospatial skills pertain to the ability to conceptualize and comprehend visual representations of objects and the spatial relationships among objects. They are integral for the proper functioning of other cognitive systems such as memory, attention, and reasoning (Kaufman, 2007). Sex hormones are one of many factors reported to affect visuospatial processing, with estrogen specially being associated with poor performance on visuospatial tasks in females (Hausmann, 2000). The current study investigated performance differences on three visuospatial …

A Field Synopsis, Systematic Review, And Meta-Analyses Of Cophylogenetic Studies: What Is Affecting Congruence Between Phylogenies?, Valeria Trivellone, Bernd Panassiti

MANTER: Journal of Parasite Biodiversity

We conducted a field synopsis and systematic meta-analysis of studies that carried out cophylogenetic analyses using algorithms and available software. We evaluated the influence of three factors—namely, cophylogenetic method, association, and ecosystem type—on the outcome of the analyses, that is, the degree of congruence between phylogenies of interacting species.

The published papers were identified using 4 different databases and 13 keywords; we included all studies for which statistical approaches to compare phylogenies (cophylogenetic analyses) of interacting lineages were used. After the initial screening, 296 studies were selected to extract response variable (outcome of the cophylogenetic analyses, i.e., congruent, incongruent, or …

Coordinate The Five-Pool Functions Of Ecosystem And Build Strong National Ecological Infrastructures—Ecological Construction Ideology, Tasks And Goals In The New Developing Era Of China, Guirui Yu, Meng Yang, Tianxiang Hao

Bulletin of Chinese Academy of Sciences (Chinese Version)

No abstract provided.

Overview Of The Role Of The Party’S Scientific Authority In Implementation Of Convention On International Trade In Endangered Species Of Wild Fauna And Flora, Jiang Zhu, Fuwen Wei

Bulletin of Chinese Academy of Sciences (Chinese Version)

Convention on International Trade in Endangered Species of Wild Fauna and Flora (CITES) aims to ensure the survival of endangered wildlife species from the threat of international trade, and is one of the powerful international conventions in the field of wildlife conservation. As an important part of the party's compliance body, scientific authority (SA) is responsible for ensuring the international wildlife trade to meet the requirements of sustainability, legality and traceability. The mandate of SA is involved into many aspects, like starting up the scientific research program for obtaining the basic information on wildlife species, providing the scientific advice for …

Research On Ecological Protection Compensation Mechanism Based On Carbon Sink Value, Lifei Jin, Haidong Zhou, Ruilin Liu

Bulletin of Chinese Academy of Sciences (Chinese Version)

The establishment of ecological protection compensation mechanism is a critical content and an important institutional guarantee for the construction of ecological civilization. Carbon peak and carbon neutrality have been included in the overall layout of the construction of ecological civilization. The optimization of ecological protection mechanism based on carbon sink value plays a pivotal role in promoting the construction of ecological civilization in China, which is an important means of regulating the fairness of "carbon neutrality" process, and will also promote the transformation of ecological protection compensation policy to refinement. Based on the connotation, attribute and realization path of carbon …

Space Science In Manned Space Flight, Deep Space Exploration And Scientific Satellite Programs, Ji Wu

Bulletin of Chinese Academy of Sciences (Chinese Version)

In order to implement President Xi's instruction on promoting space science, space technology, and space application all together, national space programs have been developed fast, which are witnessed recently. Space science has become the hot research topic for more and more universities and research institutions. Nevertheless, there are still questions and puzzles about how could space science play its role in manned spaceflight, deep space exploration, and scientific satellites. This paper discusses the role of space science in all three kinds of space programs, starting from the history of space science, and the characteristics of manned space flight, deep space …

Phase Ii Study Of Venetoclax Added To Cladribine Plus Low-Dose Cytarabine Alternating With 5-Azacitidine In Older Patients With Newly Diagnosed Acute Myeloid Leukemia, Tapan M Kadia, Patrick K Reville, Xuemei Wang, Caitlin R Rausch, Gautam Borthakur, Naveen Pemmaraju, Naval G Daver, Courtney D Dinardo, Koji Sasaki, Ghayas C Issa, Maro Ohanian, Guillermo Montalban-Bravo, Nicholas J Short, Nitin Jain, Alessandra Ferrajoli, Kapil N Bhalla, Elias Jabbour, Koichi Takahashi, Rashmi Malla, Kelly Quagliato, Rashmi Kanagal-Shamanna, Uday R Popat, Michael Andreeff, Guillermo Garcia-Manero, Marina Y Konopleva, Farhad Ravandi, Hagop M Kantarjian

Faculty, Staff and Student Publications

PURPOSE: The combination of venetoclax and 5-azacitidine (5-AZA) for older or unfit patients with acute myeloid leukemia (AML) improves remission rates and survival compared with 5-AZA alone. We hypothesized that the addition of venetoclax to cladribine (CLAD)/low-dose araC (low-dose cytarabine [LDAC]) alternating with 5-AZA backbone may further improve outcomes for older patients with newly diagnosed AML.

METHODS: This is a phase II study investigating the combination of venetoclax and CLAD/LDAC alternating with venetoclax and 5-AZA in older (≥ 60 years) or unfit patients with newly diagnosed AML. The primary objective was composite complete response (CR) rate (CR plus CR with …

Bob: Bayesian Optimal Design For Biosimilar Trials With Co-Primary Endpoints, Xiaohan Chi, Zhangsheng Yu, Ruitao Lin

Faculty, Staff and Student Publications

For regulatory approval of a biosimilar product, extensive evaluations should be performed by rigorous clinical trials to establish the similarity between the reference product and the proposed biosimilar in terms of both efficacy and safety. Existing designs for biosimilar trials often use a single primary efficacy endpoint in trial monitoring, and then separately evaluate the safety of the biosimilar product in a secondary analysis at the trial completion. However, ignoring the safety endpoint and the correlation between safety and efficacy in trial monitoring may lead to a high false positive rate, or it may delay the termination of the trial …

Reflecting On Unclos Forty Years Later: What Worked, What Failed, Raul (Pete) Pedrozo

International Law Studies

The United Nations Convention on the Law of the Sea (UNCLOS) was opened for signature on December 10, 1982, after nine years of painstaking debate. Hailed as “A Constitution for the Oceans,” the Convention was immediately signed by 119 States, a remarkable number given the contentious and complex nature of the negotiations, and today has 168 parties. The intent of the Conference that drafted the treaty was to produce a comprehensive and universally accepted convention covering every aspect of the uses and resources of the oceans that would stand the test of time. This article analyzes the various provisions of …

Monitoring The Recruitment And Fusion Of Autophagosomes To Phagosomes During The Clearance Of Apoptotic Cells In The Nematode Caenorhabditis Elegans, Omar Peña-Ramos, Zheng Zhou

Faculty, Staff and Students Publications

During an animal's development, a large number of cells undergo apoptosis, a suicidal form of death. These cells are promptly phagocytosed by other cells and degraded inside phagosomes. The recognition, engulfment, and degradation of apoptotic cells is an evolutionarily conserved process occurring in all metazoans. Recently, we discovered a novel event in the nematode Caenorhabditis elegans: the double-membrane autophagosomes are recruited to the surface of phagosomes; subsequently, the outer membrane of an autophagosome fuses with the phagosomal membrane, allowing the inner vesicle to enter the phagosomal lumen and accumulate there over time. This event facilitates the degradation of the apoptotic …

Orthochirus Katerinae Sp. N. (Scorpiones: Buthidae) From Saudi Arabia, František Kovařík, Pavel Just

Euscorpius

We describe a new species Orthochirus katerinae sp. n. from Saudi Arabia, previously cited as Orthochirus innesi Simon 1910, ssp. ?, the name many years used as an ‘umbrella’ for various Orthochirus from North Africa and Arabia. The new species is described based on males characterized mainly by: total length 26–30 mm; pectinal teeth number 16–20; movable finger of pedipalps with 7–8 rows of denticles, 8–9 ID and 7 OD; tarsomere I of legs I–III with 3–5 long setae; ratio length/width of metasoma V 1.13–1.16; pedipalp femur length/width ratio 3.30–3.32.

Il-33 Promotes Increased Replication Of Theiler’S Murine Encephalomyelitis Virus In Raw264.7 Macrophage Cells With An Irf3-Dependent Response, Ahmed Esmael, Thomas M. Petro

Nebraska Center for Virology: Faculty Publications

Interleukin-33 (IL-33), which promotes M2 macrophage development, may influence the control of viruses, such as Theiler’s Murine Encephalomyelitis Virus (TMEV) that infect macrophages. Because Interferon Regulatory Factor-3 (IRF3) is also critical to control of TMEV infection in macrophages, information on the relationship between IL-33 and IRF3 is important. Thus, RAW264.7 Lucia murine macrophage lineage cells with an endogenous IRF3-ISRE promoter driving secreted luciferase and IRF3KO RAW Lucia, a subline deficient in IRF3, were challenged with TMEV. After the challenge, considerable TMEV RNA detected at 18 and 24 h in RAW cells was significantly elevated in IRF3KO RAW cells. TMEV induction …

Transposable Element-Mediated Rearrangements Are Prevalent In Human Genomes., Parithi Balachandran, Isha A Walawalkar, Jacob I Flores, Jacob N Dayton, Peter A Audano, Christine R Beck

Faculty Research 2022

Transposable elements constitute about half of human genomes, and their role in generating human variation through retrotransposition is broadly studied and appreciated. Structural variants mediated by transposons, which we call transposable element-mediated rearrangements (TEMRs), are less well studied, and the mechanisms leading to their formation as well as their broader impact on human diversity are poorly understood. Here, we identify 493 unique TEMRs across the genomes of three individuals. While homology directed repair is the dominant driver of TEMRs, our sequence-resolved TEMR resource allows us to identify complex inversion breakpoints, triplications or other high copy number polymorphisms, and additional complexities. …

The Socialization Experiences Of African American Women In Higher Education Student Affairs, Erica Ogburn

Doctoral Dissertations

A qualitative, instrumental case study approach with multiple embedded cases guided the examination of each African American woman’s experience in socialization across various higher education institutions. Due to the intersectional identities of African American women, the theoretical framework for the current study uses both the newcomer’s adjustment framework and Black feminist thought (BFT). The findings include the following: 1) African American women in higher education student affairs experience a lack of official training and onboarding, 2) In the various roles held by African American women, they take on advanced commitments to Black and minority student populations, causing feelings of being …

Effectiveness Of Clay Nanotube Blended Coating Materials For Thermal Insulation, Hawa Hashm

Doctoral Dissertations

Studies conducted by the U.S. Department of Energy reported that heating and cooling systems use nearly 60% of the total energy consumed in a building, while approximately 31% of that energy loss occurs through the improperly insulated floor, walls, and ceiling. Hot summers or severely cold weather can make these problems worse. The passing of conditioned air through these building materials is a substantial source of energy loss, which has driven significant investigation into new environmentally friendly, sustainable, and cost-effective solutions. The main objective of the research was to experimentally evaluate the thermal conductivity of paints blended with halloysite nanotubes …

Lewis-Base Thioacetamide Assisted Crystallization Of Lead-Free Perovskite Solar Cells For Improved Efficiency, Raja Sekhar Bobba

Dissertations - ALL

High-efficiency perovskite solar cells that are also very cheap to produce have been rapidly developed in response to the growing global demand for electricity. However, the light absorber materials used in cutting-edge perovskite solar cells include lead, which has been linked to health risks for people and other living organisms. Accordingly, the developing front in photovoltaic research is the discovery and development of new lead-free perovskite materials for the future global commercialization of non-toxic, stable, and efficient perovskite solar cells, by replacing hazardous lead with non-toxic metal elements in the same group as lead in the periodic table, lead-free PSCs …

Faith Integration In Stem Courses For Undergraduates: Exemplars Of Pedagogical Practices, David Klanderman, Clayton Carlson, Tina Decker, Fred Haan, Victor T. Norman, Abbie Schrotenboer, Derek Schuurman, James Turner

University Faculty Publications and Creative Works

In his book On Christian Teaching, David Smith offers multiple ways in which one’s Christian faith commitments influence pedagogical practices. Specific examples are drawn from the humanities, particularly from languages and literature. Some may conclude that such discussions are less appropriate in areas such as science, technology, engineering, and mathematics (STEM). We disagree and offer exemplars aligned with a set of six curricular criteria identified by Wayne Au. We argue that these exemplars emerge naturally from our Christian beliefs and are “faith-influenced” even if not every strategy embodies a narrower integration of faith and pedagogy.

Postdigital Soundscapes: Sonics, Pedagogies, Technologies, Derek Ford

Education Studies Faculty publications

No abstract provided.

Cardiovascular/Stroke Risk Stratification In Diabetic Foot Infection Patients Using Deep Learning-Based Artificial Intelligence: An Investigative Study., Narendra N Khanna, Mahesh A Maindarkar, Vijay Viswanathan, Anudeep Puvvula, Sudip Paul, Mrinalini Bhagawati, Puneet Ahluwalia, Zoltan Ruzsa, Aditya Sharma, Raghu Kolluri, Padukone R Krishnan, Inder M Singh, John R Laird, Mostafa Fatemi, Azra Alizad, Surinder K Dhanjil, Luca Saba, Antonella Balestrieri, Gavino Faa, Kosmas I Paraskevas, Durga Prasanna Misra, Vikas Agarwal, Aman Sharma, Jagjit S Teji, Mustafa Al-Maini, Andrew Nicolaides, Vijay Rathore, Subbaram Naidu, Kiera Liblik, Amer M Johri, Monika Turk, David W Sobel, Martin Miner, Klaudija Viskovic, George Tsoulfas, Athanasios D Protogerou, Sophie Mavrogeni, George D Kitas, Mostafa M Fouda, Mannudeep K Kalra, Jasjit S Suri

Heart and Vascular Articles

A diabetic foot infection (DFI) is among the most serious, incurable, and costly to treat conditions. The presence of a DFI renders machine learning (ML) systems extremely nonlinear, posing difficulties in CVD/stroke risk stratification. In addition, there is a limited number of well-explained ML paradigms due to comorbidity, sample size limits, and weak scientific and clinical validation methodologies. Deep neural networks (DNN) are potent machines for learning that generalize nonlinear situations. The objective of this article is to propose a novel investigation of deep learning (DL) solutions for predicting CVD/stroke risk in DFI patients. The Preferred Reporting Items for Systematic …

An Interactionist Approach To Btlg Pride, Lain A.B. Mathers, Jason E. Sumerau

The Qualitative Report

Within and beyond Symbolic Interactionism, sociological studies of bisexual, transgender, lesbian, and gay (BTLG) populations have expanded dramatically in the past two decades. Although such studies have invigorated our understanding of many aspects of BTLG life and experience, they have thus far left BTLG Pride relatively unexplored. How do BTLG populations experience Pride, and what insights might such efforts have for sociologically understanding such populations and events? We examine these questions through an interview study of bi+ people (i.e., sexually fluid people who identify as bisexual, pansexual, or otherwise outside of gay/straight binaries; Eisner, 2013). Specifically, we analyze how bi+ …