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2022

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Perspectives Of Power: Phenomenological Inquiry Exploring The Manifestation Of Power In Doctoral Programs, Sharazazi Dyson Jan 2022

Perspectives Of Power: Phenomenological Inquiry Exploring The Manifestation Of Power In Doctoral Programs, Sharazazi Dyson

Graduate Research Theses & Dissertations

The research questions guiding this study include: How do doctoral-level students or recent graduates of color within counselor education and supervision programs describe the manifestations of power in the context of their program and university? What experiences with power do counselor educators in training (CEITs) cite as memorable in their counseling program? A phenomenological-based approach was chosen to understand the experiences with power. Using purposive and criterion sampling methods, three participants were recruited and selected. Rich descriptions of participants’ experiences with power were obtained by conducting semi-structured interviews composed of open-ended questions. Using the modified Stevick-Colaizzi-Keen method as described by …

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Nutrient Scarcity And Cellular Cooperation In A Clonal Hydroid, Weam S. El Rahmany Jan 2022

Nutrient Scarcity And Cellular Cooperation In A Clonal Hydroid, Weam S. El Rahmany

Graduate Research Theses & Dissertations

Biological complexity forms when lower-level units (e.g., genes, cells, organisms) cooperatively band together. This complexity may be exemplified by multicellularity, the cooperation between the cells of the same species, or symbiosis, cooperation between the cells of different species. This cooperation is under continual threat, as defection, the opposite of cooperation, is favored by default by lower-level units (i.e., cells). Animal cancers may be the most well-known phenomena that exemplify the concept of cellular defection. Cancer cells have been shown to feature morphological and metabolic traits, developed through differential gene expression or mutations, that favor their growth at the cost of …

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Postsecondary Course-Taking And Academic Performance Of Transitional Math Completers: A Quantitative Study Of Students In Illinois, Gina Caronna Jan 2022

Postsecondary Course-Taking And Academic Performance Of Transitional Math Completers: A Quantitative Study Of Students In Illinois, Gina Caronna

Graduate Research Theses & Dissertations

This quantitative study investigated the academic outcomes of high school students from one community college district in Illinois who took a high school transitional math course designed to give them direct placement into a college-level math course. The goal of successful completion of a transitional math course is to allow students direct placement into college-level math courses. This study provides a correlational analysis of specific academic success metrics between students who took transitional math and those who did not at one Illinois community college. The sample for this study included 100 students who completed a transitional math course and 525 …

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A Qualitative Case Study Examining Women Of Color’S Experiences As They Pursue A Criminal Justice Degree, David John Dammon Ii Jan 2022

A Qualitative Case Study Examining Women Of Color’S Experiences As They Pursue A Criminal Justice Degree, David John Dammon Ii

Graduate Research Theses & Dissertations

This dissertation examined the experiences of women of color (WOC), defined as African American and Latina women for this study, as they pursued a degree in a criminal justice program at a Midwest community college. Utilizing Schlossberg’s transition theory, the qualitative case study sought to learn how WOC experience the transition to being students in a criminal justice program and the support and strategies they utilized to adjust to and navigate it. The study sought to fill a gap in the literature on WOC seeking degrees in criminal justice programs. The study also sought to learn more about student experience …

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The Psychological Roots Of William James's Thought, David E. Leary Jan 2022

The Psychological Roots Of William James's Thought, David E. Leary

Psychology Faculty Publications

"... [H]ow exactly did James’s personal characteristics, experiences, and concerns impact upon his philosophy? To answer that question we will need to look further back, well before he started publishing the works for which he is best known within philosophy: before, that is, Prag-matism (1907), A Pluralistic Universe (1909), The Meaning of Truth (1909), and the posthumously collected Essays in Radical Empiricism (1912). Before and behind these works was the work that Santayana (among many others) called James’s greatest achievement (Santayana 1920/2009: 585); namely, his monumental Principles of Psychology (1890).2 So the questions we need to ask are: (1) What …

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Early Life Stress Inoculation Effects On Adult Behaviors, Oreoluwa Ibukunolupo Akinbo Jan 2022

Early Life Stress Inoculation Effects On Adult Behaviors, Oreoluwa Ibukunolupo Akinbo

Graduate Research Theses & Dissertations

Chronic and acute stressors are implicated in mental illnesses such as depression, anxiety and posttraumatic disorder. These adulthood disorders may be influenced by stressor exposure during early life. However, controlled mild stressors are linked to the building of resiliency towards later intense stressors. Previously, rodent models have been used to investigate the resilience-promoting effects of early life stress inoculation protocols. For example, the presentation of mild stressors (such as an experimenter handling a rodent for brief periods of time) or exposure to environmental enrichment (such as a presenting a variety of items and activities in the home cage of a …

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Termination Of Parental Rights As A Private Remedy: Rationales, Realities, And Remedies, Deirdre M. Smith Jan 2022

Termination Of Parental Rights As A Private Remedy: Rationales, Realities, And Remedies, Deirdre M. Smith

Faculty Publications

Terminating a parent’s rights—a drastic measure—is commonly associated with public child welfare proceedings, where a state or county child protective services agency has removed a child from their home based on findings of abuse or neglect. In fact, state laws across the country also permit private individuals to petition a court to terminate another person’s parental rights. While private termination actions are not uncommon, there has been scant scholarly examination of these matters, their underlying purposes, and their role in contemporary family law. Termination of parental rights orders in any context interfere with parents’ fundamental constitutional rights, but parents in …

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The Boundaries Of Multi-Parentage, Jessica Feinberg Jan 2022

The Boundaries Of Multi-Parentage, Jessica Feinberg

Faculty Publications

Multi-parentage has arrived. In recent years, a growing number of courts and legislatures have recognized that a child may have more than two legal parents. A number of significant societal, medical, and legal developments have contributed to the trend toward multi-parentage recognition. The traditional family structure of a married different-sex couple and their biological children currently represents only a minority of U.S. families. Stepparents, non-marital partners of legal parents, and extended family members often play a significant role in children’s lives, and it has become increasingly common for same-sex couples to welcome children into their families. In addition, advancements in …

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Sars-Cov-2 Vaccine: First-Month Results Of A Six-Month Follow-Up Study, Burak Mete, Ferdi̇ Tanir, Hakan Demi̇rhi̇ndi̇, Ertan Kara, Fi̇li̇z Ki̇bar, Sali̇h Çeti̇ner, Aslihan Candevi̇r, Rabi̇a Adevi̇yye Dal Jan 2022

Sars-Cov-2 Vaccine: First-Month Results Of A Six-Month Follow-Up Study, Burak Mete, Ferdi̇ Tanir, Hakan Demi̇rhi̇ndi̇, Ertan Kara, Fi̇li̇z Ki̇bar, Sali̇h Çeti̇ner, Aslihan Candevi̇r, Rabi̇a Adevi̇yye Dal

Turkish Journal of Medical Sciences

Background/aim: Various COVID-19 vaccines are being developed around the world. Important questions to be answered regarding vaccines are efficacy, safety, and whether antibodies are protective when used in different communities. This study aimed to determine seroconversion rates of the inactivated SARS-CoV-2 vaccine in healthcare workers in a hospital and short-term adverse events due to the vaccine. Materials and methods: The study carried out in Çukurova University, Turkey, comprised of 282 healthcare workers who received two doses of the inactivated SARS-CoV-2 vaccine administered in two 3 μg doses, 28 days apart. On day 28, after the second dose, anti- S-RBD IgG …

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Efficacy Of Eltrombopag In Thrombocytopenia After Hematopoietic Stem Celltransplantation, Ayşe Karataş, Hakan Göker, Haluk Demi̇roğlu, Ümi̇t Yavuz Malkan, Mustafa Velet, Olgu Erki̇n Çinar, Batuhan Erdoğdu, Mi̇ne Karadeni̇z, Ni̇lgün Sayinalp, Sali̇h Aksu, İbrahi̇m Celaletti̇n Haznedaroğlu, Osman İlhami̇ Özcebe, Yahya Büyükaşik Jan 2022

Efficacy Of Eltrombopag In Thrombocytopenia After Hematopoietic Stem Celltransplantation, Ayşe Karataş, Hakan Göker, Haluk Demi̇roğlu, Ümi̇t Yavuz Malkan, Mustafa Velet, Olgu Erki̇n Çinar, Batuhan Erdoğdu, Mi̇ne Karadeni̇z, Ni̇lgün Sayinalp, Sali̇h Aksu, İbrahi̇m Celaletti̇n Haznedaroğlu, Osman İlhami̇ Özcebe, Yahya Büyükaşik

Turkish Journal of Medical Sciences

Background/aim: Thrombocytopenia is a common complication following hematopoietic stem cell transplantation (HSCT). Eltrombopag has been used in thrombocytopenia treatment after HSCT in recent years. Herein, we present our experience of 25 patients treated with eltrombopag for post-HSCT thrombocytopenia. Materials and methods: Fifteen autologous hematopoietic stem cell transplantation (AHSCT) and 10 allogenic hematopoietic stem cell transplantation (allo-HSCT) recipients treated with eltrombopag for treatment of prolonged isolated thrombocytopenia (PIT) or secondary failure of platelet recovery (SFPR) in the stem cell transplantation unit of Hacettepe University Hematology Department between 2017 and 2021 were included in the study. The primary endpoint of this study …

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The Clinical Follow-Up And Management Of Covid-19 In Children And Adolescents Withan Immunocompromised State Or A Malignancy, İrem Ceren Erbaş, Hati̇ce Karaoğlu Asrak, Ayşe Çakil Güzi̇n, Şi̇lem Özdem Alataş, Şefi̇ka Akyol, Meral Torun Bayram, Refi̇k Emre Çeçen, Di̇lek İnce, Özlem Tüfekçi̇, Nurşen Belet Jan 2022

The Clinical Follow-Up And Management Of Covid-19 In Children And Adolescents Withan Immunocompromised State Or A Malignancy, İrem Ceren Erbaş, Hati̇ce Karaoğlu Asrak, Ayşe Çakil Güzi̇n, Şi̇lem Özdem Alataş, Şefi̇ka Akyol, Meral Torun Bayram, Refi̇k Emre Çeçen, Di̇lek İnce, Özlem Tüfekçi̇, Nurşen Belet

Turkish Journal of Medical Sciences

Background/aim: It is still not known how an immunosuppressive state affects the response to coronavirus disease 2019 (COVID-19) in children and adolescents. The aim of this study was to evaluate clinical characteristics, outcomes, and follow-up results of COVID-19 in pediatric patients with a history of immunocompromise or malignancy, retrospectively. Materials and methods: Patients with a diagnosis of COVID-19 who were under 18 years of age and had a history of immunosuppressive chronic disease or under immunosuppressant treatment were included in the study. Patients were applied to our outpatient clinic or consulted to our department in a tertiary center during the …

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Evaluation Of Plasma Carnitine Status In Patients Diagnosed With Juvenile Idiopathic Arthritis, Ayşe Çi̇ğdem Aktuğlu Zeybek, Ertuğrul Kiykim, Kenan Barut, Tanyel Zübari̇oğlu, Mehmet Şeri̇f Cansever, Özgür Kasapçopur Jan 2022

Evaluation Of Plasma Carnitine Status In Patients Diagnosed With Juvenile Idiopathic Arthritis, Ayşe Çi̇ğdem Aktuğlu Zeybek, Ertuğrul Kiykim, Kenan Barut, Tanyel Zübari̇oğlu, Mehmet Şeri̇f Cansever, Özgür Kasapçopur

Turkish Journal of Medical Sciences

No abstract provided.

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The Validity And Clinical Utility Of Axillary Ultrasonography-Guided Fine Needle Aspiration Biopsy In Detection Of Nodal Metastasis In Early-Stage Breast Cancer Patients: A Retrospective Single-Center Experience, Fi̇li̇z Taşçi, Yavuz Meti̇n, Nurgül Orhan Meti̇n, Maksude Esra Kadioğlu, Meli̇h Gaffar Gözükara, Si̇bel Kul Jan 2022

The Validity And Clinical Utility Of Axillary Ultrasonography-Guided Fine Needle Aspiration Biopsy In Detection Of Nodal Metastasis In Early-Stage Breast Cancer Patients: A Retrospective Single-Center Experience, Fi̇li̇z Taşçi, Yavuz Meti̇n, Nurgül Orhan Meti̇n, Maksude Esra Kadioğlu, Meli̇h Gaffar Gözükara, Si̇bel Kul

Turkish Journal of Medical Sciences

Background/aim: Assessing the validity and clinical utility of axillary ultrasonography (AUS)-guided fine needle aspiration biopsy (FNAB) in detection of nodal metastasis during preoperative axillary investigation in comparison to the histopathologic diagnosis in early-stage breast cancer. Materials and methods: A total of 279 operated primary breast cancer patients (age: 55.3 ± 12.8, ranged 17-90 years) were included. Data on AUS findings at the time of initial diagnosis (first look AUS), second-look AUS findings performed by the breast radiologist during breast biopsy procedure and the AUS-guided FNAB findings were evaluated with respect to the final histopathology report obtained through axillary surgery via …

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The Clinical, Pathological, And Genetic Characteristics Of Lipid Storage Myopathy In Northern China, Jingzhe Han, Shan Lu, Xueqin Song, Guang Ji, Yanan Xie, Hongran Wu Jan 2022

The Clinical, Pathological, And Genetic Characteristics Of Lipid Storage Myopathy In Northern China, Jingzhe Han, Shan Lu, Xueqin Song, Guang Ji, Yanan Xie, Hongran Wu

Turkish Journal of Medical Sciences

Background/aim: The lipid storage myopathy (LSM) diagnosis is based on the patient's clinical manifestations and muscle pathology. However, when genetic testing is lacking, there is a high rate of misdiagnosis of the disease. This study aimed to investigate the clinical and pathological features of genetically diagnosed LSM in northern China, analyze genetic mutations' characteristics, and improve the LSM diagnostic rate. Materials and methods: Twenty patients with LSM diagnosed were collected; meanwhile, the clinical data, muscle samples, and routine pathological staining of muscle specimens were collected. The morphological changes of muscle fibers were observed under an optical microscope. Results: Among the …

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Egfr Blocker Lapatinib Inhibits The Synthesis Of Matrix Metalloproteinases From Synovial Fibroblasts, Demet Yalçin Kehri̇bar, Hakan Emmungi̇l, Neşe Başak Türkmen, Osman Çi̇ftçi̇, Emi̇ne Şalva, Meti̇n Özgen Jan 2022

Egfr Blocker Lapatinib Inhibits The Synthesis Of Matrix Metalloproteinases From Synovial Fibroblasts, Demet Yalçin Kehri̇bar, Hakan Emmungi̇l, Neşe Başak Türkmen, Osman Çi̇ftçi̇, Emi̇ne Şalva, Meti̇n Özgen

Turkish Journal of Medical Sciences

Background/aim: Epidermal growth factor receptor (EGFR) family members and their associated ligands may be related to bone and joint destruction in rheumatoid arthritis. Matrix metalloproteinases are responsible for joint and bone tissue degradation. This study is intended to investigate the effect of epidermal growth factor receptor inhibition by lapatinib on the synthesis of matrix metalloproteinases in in vitro. Materials and methods: Synovial fibroblast cell culture was obtained from a patient with rheumatoid arthritis who underwent knee arthroplasty. Interleukin-1ß (IL-1ß) and tumor necrosis factor-∝ (TNF-∝) were added to the cell culture to stimulate synovial fibroblast cells and create an inflammatory character. …

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What Is The Protective Effect Of Preischemic Kisspeptin-10 Administration Against Ischemia/Reperfusion Injury Of Striatum On Mice?, Hati̇ce Akkaya, Engi̇n Sümer, Seli̇m Kutlu, Hati̇ce Solak, Bayram Yilmaz Jan 2022

What Is The Protective Effect Of Preischemic Kisspeptin-10 Administration Against Ischemia/Reperfusion Injury Of Striatum On Mice?, Hati̇ce Akkaya, Engi̇n Sümer, Seli̇m Kutlu, Hati̇ce Solak, Bayram Yilmaz

Turkish Journal of Medical Sciences

Background/aim: Kisspeptin is a neuropeptide with a primary role on the onset of puberty and has beneficial effects on ischemia/ reperfusion (I/R) injury. In this study, we aimed to investigate the effect of kisspeptin administration on striatal I/R injury in mice. Material and methods: Forty adult C57/BL6 mice were randomly divided into four groups: Sham, Kisspeptin, I/R, and I/R + Kisspeptin groups. The groups were administered with either physiological saline (Sham and I/R groups) or kisspeptin (Kisspeptin and I/R + Kisspeptin groups) intraperitoneally 40 min before the operation. A microdialysis probe was placed in the right striatum according to stereotaxic …

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Frailty In Community-Dwelling Older Adults: Reliability And Validity Of The Turkish Version Of The Gérontopôle Frailty Screening Tool, Serdar Ceylan, Merve Güner Oytun, Arzu Okyar Baş, Meltem Koca, Burcu Balam Doğu, Meltem Gülhan Hali̇l, Mustafa Cankurtaran, Cafer Balci Jan 2022

Frailty In Community-Dwelling Older Adults: Reliability And Validity Of The Turkish Version Of The Gérontopôle Frailty Screening Tool, Serdar Ceylan, Merve Güner Oytun, Arzu Okyar Baş, Meltem Koca, Burcu Balam Doğu, Meltem Gülhan Hali̇l, Mustafa Cankurtaran, Cafer Balci

Turkish Journal of Medical Sciences

Background/aim: Recognizing frailty had a great importance in countries with an increasing geriatric population. The study aims to evaluate the reliability and validation of the Gérontopôle frailty screening tool (GFST), which was developed to screen frailty in the community-dwelling older adults, for the Turkish population. Materials and methods: In this crosssectional study, participants who applied to the geriatrics outpatient clinic of a university hospital were included. Comprehensive geriatric assessments of all patients were performed. The validity of the GFST was tested by its concordance with the FRAIL scale. Test-retest and interrater reliability analyses were made. Results: Ninety-six patients were included …

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Copper(Ii) And Silver(I)‑1,10‑Phenanthroline‑5,6‑Dione Complexes Interact With Double‑Stranded Dna: Further Evidence Of Their Apparent Multi‑Modal Activity Towards Pseudomonas Aeruginosa, Anna Clara Milesi Galdino, Lívia Viganor, Matheus Mendonça Pereira, Michael Devereux, Malachy Mccann, Marta Helena Branquinha, Zara Molphy, Sinéad O'Carroll, Conor Bain, Georgia Menounou, Andrew Kellett, André Luis Souza Dos Santos Jan 2022

Copper(Ii) And Silver(I)‑1,10‑Phenanthroline‑5,6‑Dione Complexes Interact With Double‑Stranded Dna: Further Evidence Of Their Apparent Multi‑Modal Activity Towards Pseudomonas Aeruginosa, Anna Clara Milesi Galdino, Lívia Viganor, Matheus Mendonça Pereira, Michael Devereux, Malachy Mccann, Marta Helena Branquinha, Zara Molphy, Sinéad O'Carroll, Conor Bain, Georgia Menounou, Andrew Kellett, André Luis Souza Dos Santos

Articles

Tackling microbial resistance requires continuous efforts for the development of new molecules with novel mechanisms of action and potent antimicrobial activity. Our group has previously identified metal-based compounds, [Ag(1,10-phenanthroline-5,6-dione)2]ClO4 (Ag-phendione) and [Cu(1,10-phenanthroline-5,6-dione)3](ClO4)2.4H2O (Cu-phendione), with efficient antimicrobial action against multidrug-resistant species. Herein, we investigated the ability of Ag-phendione and Cu-phendione to bind with double-stranded DNA using a combination of in silico and in vitro approaches. Molecular docking revealed that both phendione derivatives can interact with the DNA by hydrogen bonding, hydrophobic and electrostatic interactions. Cu-phendione exhibited the highest binding affinity to either major (− 7.9 kcal/mol) or minor (− 7.2 kcal/mol) …

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Role Of Host Restriction Factors On Porcine Reproductive And Respiratory Syndrome Virus (Prrsv) Replication, Pratik Katwal Jan 2022

Role Of Host Restriction Factors On Porcine Reproductive And Respiratory Syndrome Virus (Prrsv) Replication, Pratik Katwal

Electronic Theses and Dissertations

In this study, the role of IFITM3 on PRRSV replication was studied in vitro by expressing exogenous IFITM3 in MARC-145 cells. An average of 31% reduction in PRRSV N protein expression and an average of 5.4 fold decrease in virus titer in the supernatant were observed in IFITM3 overexpressing cells as compared to vector control cells at 24 hours post infection (hpi). Moreover, there was a positive correlation between interferon- induced IFITM3 up-regulation and reduced PRRSV replication. To determine the role of endogenous IFITM3 in PRRSV replication, siRNA induced knockdown of IFITM3 was employed. RT-PCR validated the successful silencing of …

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Curriculum Development Of Agricultural Educators In South Dakota, Mercedes Lemke Jan 2022

Curriculum Development Of Agricultural Educators In South Dakota, Mercedes Lemke

Electronic Theses and Dissertations

Curriculum development is an essential component of teaching. Understanding how agriculture education teachers utilize, develop, and adapt content to curriculum can benefit teachers to spend less time on curriculum development. Recognizing the way agriculture education teachers use content in curriculum implementation will allow curriculum developers to create materials that can effectively be used by teachers. This study also looked at the affects of how COVID19 pandemic affected the way teachers locate and develop curriculum. The purpose of this study was to evaluate the way agriculture education instructor’s usage of content for curriculum development, implementation decisions and the affects of the …

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Application Of Pork Checkoff We Care Sustainability Principles To Pork Production: Water, Nutrition, And Biosecurity, Hannah Miller Jan 2022

Application Of Pork Checkoff We Care Sustainability Principles To Pork Production: Water, Nutrition, And Biosecurity, Hannah Miller

Electronic Theses and Dissertations

The Pork Checkoff program was founded in 1986 as a means to strengthen U.S. pork in the market place (Pork Checkoff). Under this program all U.S. pork producers and importers pay $0.40 for every $100 worth of pigs is sold (Pork Checkoff). Funds are then used for pork promotion, research, and education for producers and consumers (Pork Checkoff). The Pork Checkoff program uses the We Care ethical principles as a means to address “continuous improvement in the pork industry’s production practices and promote a strong record of responsible farming to those outside of the industry” (National Pork Board, 2018a). The …

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Decoding The Mystery Of Antibiotic Persistence, Tahmina Hossain Jan 2022

Decoding The Mystery Of Antibiotic Persistence, Tahmina Hossain

Electronic Theses and Dissertations

This work combines microbiology, molecular biology, Next-Generation Sequencing and system biology approaches to explore the mechanism of antibiotic persistence: a multi-drug tolerant, non-dividing, and metabolically altered state present in a subpopulation of cells due to phenotypic diversity rather than genetic variation (i.e. mutations). Persister can survive lethal antibiotic state and resuscitate after the treatment period is over. They are considered as the major contributing factor behind recurring infections. They also have a high mutation rate, which increases the chances of bacteria gaining antibiotic resistance. The formation of this phenotypic variant (persister) threatens the therapeutic effectiveness of antibiotics and understanding how …

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Effect Of Essential Oils In The Control Of Fungal Diseases In Small Grains, Esneider Mahecha Bojaca Jan 2022

Effect Of Essential Oils In The Control Of Fungal Diseases In Small Grains, Esneider Mahecha Bojaca

Electronic Theses and Dissertations

Spring wheat (Triticum aestivum L.) and oats (Avena sativa L.) are important crops due to their high consumption in our daily diet worldwide. They are the main food of consumption per capita due to the high amino-acid content as well of vitamins. However, grain production is limited due to the negative impact of the diseases that cause significant yield loss. Diseases in oats, such as crown rust caused by Puccinia coronata f. sp. avenae (Pca), and in wheat such as Fusarium head blight (FHB) caused by the fungus Fusarium graminearum. Foliar diseases such as tan spot incited by the fungi …

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High Protein Yeast-Based Ddgs As An Alternative To Commonly Used Protein Sources In Pig Diets, Yesid Ricardo Garavito Duarte Jan 2022

High Protein Yeast-Based Ddgs As An Alternative To Commonly Used Protein Sources In Pig Diets, Yesid Ricardo Garavito Duarte

Electronic Theses and Dissertations

Alternative ingredients and co-products from ethanol and biofuel industries represent an opportunity for utilization in swine diets. In this context, understanding nutritional value to practical swine feeding begins with product characterization and determination of nutrient digestibility. The objective of this research was to test the hypothesis: yeast-based high-protein DDGS (HP-GDDY) has comparable AA and metabolizable energy (ME) digestibility to feedstuffs commonly used in swine diets and that it could be included as an alternative protein source in nursery diets without negative impact on growth performance. Cornstarch-based diets were formulated using six ingredients as the sole source of AA: spray dried …

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Dental Pulp Stem Cell Heterogeneity: Finding Superior Quality “Needles” In A Dental Pulpal “Haystack” For Regenerative Medicine-Based Applications, Zi Y. Kok, Nadia Y.A. Alaidaroos, Amr Alraies, John S. Colombo, Lindsay C. Davies, Rachel J. Waddington, Alastair J. Sloan, Ryan Moseley Jan 2022

Dental Pulp Stem Cell Heterogeneity: Finding Superior Quality “Needles” In A Dental Pulpal “Haystack” For Regenerative Medicine-Based Applications, Zi Y. Kok, Nadia Y.A. Alaidaroos, Amr Alraies, John S. Colombo, Lindsay C. Davies, Rachel J. Waddington, Alastair J. Sloan, Ryan Moseley

Dental Medicine Faculty Research

Human dental pulp stem/stromal cells (hDPSCs) derived from the permanent secondary dentition are recognised to possess certain advantageous traits, which support their potential use as a viable source of mesenchymal stem/stromal cells (MSCs) for regenerative medicine-based applications. However, the well-established heterogeneous nature of hDPSC subpopulations, coupled with their limited numbers within dental pulp tissues, has impeded our understanding of hDPSC biology and the translation of sufficient quantities of these cells from laboratory research, through successful therapy development and clinical applications. This article reviews our current understanding of hDPSC biology and the evidence underpinning the molecular basis of their heterogeneity, which …

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Toward Building Science Literacy, Kathryn Rafferty Jan 2022

Toward Building Science Literacy, Kathryn Rafferty

UNLV Best Teaching Practices Expo

Reading scientific literature is a critical science competency that proves difficult to “teach.” Students enter our classes with varying science vocabularies, and many suffer imposter syndrome when reading technical reports because they do not yet identify as capable scientists. The “Science Literacy” assignment guides students to develop and expand strategies to read science articles. Over the semester, students read 5 to 6 articles ranging from peer-reviewed manuscripts to popular science magazines to science blogs about sequencing Ozzy Osbourne's DNA. In Canvas Discussion boards, they a guiding set of questions and then respond to their peers. This assignment is a low-stakes …

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An Integrative Approach To Teaching In Precalculus And Calculus Classes, Aleksei Talonov Jan 2022

An Integrative Approach To Teaching In Precalculus And Calculus Classes, Aleksei Talonov

UNLV Best Teaching Practices Expo

We would like to present practices of using problem-based learning activities in Mathematics classroom. We mostly concentrated our attention on Precalculus and Calculus classes which have had low success rates and retention. During the last couple of years, we developed a set of course specific materials in the form of lecture notes and inclass and out-of-class assignments. Each major assignment is accompanied by clear and coherent guidelines explaining what kind of skills will be attained by practicing this assignment, how it can be done, what amount of time can it reasonably take, when is it due, and where to get …

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Xrcc4 And Mre11 Roles And Transcriptional Response To Repair Of Talen-Induced Double-Strand Dna Breaks, Ronald Benjamin, Atoshi Banerjee, Xiaogang Wu, Corey Geurink, Lindsay Buczek, Danielle Eames, Sara G. Trimidal, Janice M. Pluth, Martin R. Schiller Jan 2022

Xrcc4 And Mre11 Roles And Transcriptional Response To Repair Of Talen-Induced Double-Strand Dna Breaks, Ronald Benjamin, Atoshi Banerjee, Xiaogang Wu, Corey Geurink, Lindsay Buczek, Danielle Eames, Sara G. Trimidal, Janice M. Pluth, Martin R. Schiller

Health Physics and Diagnostic Sciences Faculty Research

Double-strand breaks (DSB) are one of the most lethal forms of DNA damage that, if left unrepaired, can lead to genomic instability, cellular transformation, and cell death. In this work, we examined how repair of transcription activator-like effector nuclease (TALEN)-induced DNA damage was altered when knocking out, or inhibiting a function of, two DNA repair proteins, XRCC4 and MRE11, respectively. We developed a fluorescent reporter assay that uses TALENs to introduce DSB and detected repair by the presence of GFP fluorescence. We observed repair of TALEN-induced breaks in the XRCC4 knockout cells treated with mirin (a pharmacological inhibitor of MRE11 …

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Mobile Health App For Adolescents: Motion Sensor Data And Deep Learning Technique To Examine The Relationship Between Obesity And Walking Patterns, Sungchul Lee, Eunmin Hwang, Yanghee Kim, Fatih Demir, Hyunhwa Lee, Joshua J. Mosher, Eunyoung Jang, Kiho Lim Jan 2022

Mobile Health App For Adolescents: Motion Sensor Data And Deep Learning Technique To Examine The Relationship Between Obesity And Walking Patterns, Sungchul Lee, Eunmin Hwang, Yanghee Kim, Fatih Demir, Hyunhwa Lee, Joshua J. Mosher, Eunyoung Jang, Kiho Lim

Nursing Faculty Research

With the prevalence of obesity in adolescents, and its long-term influence on their overall health, there is a large body of research exploring better ways to reduce the rate of obesity. A traditional way of maintaining an adequate body mass index (BMI), calculated by measuring the weight and height of an individual, is no longer enough, and we are in need of a better health care tool. Therefore, the current research proposes an easier method that offers instant and real-time feedback to the users from the data collected from the motion sensors of a smartphone. The study utilized the mHealth …

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Power In A Pandemic: Teachers’ Unions And Their Responses To School Reopening, Bradley D. Marianno, Annie A. Hemphill, Ana Paula S. Loures-Elias, Libna Garcia, Deanna Cooper, Emily Coombes Jan 2022

Power In A Pandemic: Teachers’ Unions And Their Responses To School Reopening, Bradley D. Marianno, Annie A. Hemphill, Ana Paula S. Loures-Elias, Libna Garcia, Deanna Cooper, Emily Coombes

Educational Psychology, Leadership, and Higher Education Faculty Research

Drawing on Bachrach and Baratz’s first and second faces of interest group power, we explore the relationship between teachers’ union power and reopening decisions during the fall 2020 semester in 250 large districts around the United States. We leverage a self-collected panel data set of reopening decisions coupled with measures of teachers’ union first face power (drawn from social media postings on teachers’ unions’ Facebook pages) and second face power (operationalized as district size, whether the school district negotiates a collective bargaining agreement with the teachers’ union, the length of the collective bargaining agreement, and the amount of revenue raised …

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