Digital Commons Network^™

2022-2023 Nursing Undergraduate Student Handbook, Morehead State University. Nursing Department.

Nursing Department Publications Archive

2022-2023 Undergraduate Student Handbook of the Department of Nursing at Morehead State University.

Bibliometric Study On The Literature Related To Dental Research And Education Published In Journal Of Pakistan Medical Association, Samira Adnan, Kamil Zafar, Farhan Raza Khan, Rizwan Ullah

Section of Dental-Oral Maxillofacial Surgery

Objective: To analyse characteristics of literature related to dental research and education published in a single medical journal, The Journal of Pakistan Medical Association.
Method: The bibliometric study was conducted at the Sindh Institute of Oral Health Sciences, Jinnah Sindh Medical University from March till May 2020, and comprised electronic and hand search of scientific literature relevant to dentistry published in the Journal of Pakistan Medical Association from the first issue published in 1953 till March 2020. The selected articles were analysed for year of publication, field of study, type of article, institute and country of first author, number of …

Impact Of Co-Culturing Bacteria Upon Antibiotic Production, Zora Westwalewicz

Senior Honors Theses and Projects

The lack of new antibiotics capable of treating the ever-increasing number of antibiotic-resistant bacterial infections reflects the difficulty of finding new antimicrobial compounds. Most antibiotics were originally discovered from microorganisms that were grown in isolation. The interspecies interactions involved in co-culturing microbes, growing two or more strains together, can impact the types and increase production levels of antimicrobial compounds compared to monocultures. The purpose of this study was to determine whether co-culturing antibacterial producers would result in increased antibiotic production. Mixed student samples from the EMU Tiny Earth lab were utilized for this study because there was a higher chance …

Decomposition Of Organic Matter Above And Below Dams, Olivia Muntz

Senior Honors Theses and Projects

Dams produce hydroelectric power and control flooding, but they also cause negative ecological consequences such as habitat fragmentation and altered water quality. The goal of this study was to determine whether dams alter rates of organic matter decomposition. Decomposition rates in impoundments and in free-flowing sections of the Huron River were measured using the cotton strip assay. We hypothesized that if water temperature is the main driver of decomposition rates, then higher rates of decomposition would be expected behind dams due to anticipated warmer water temperatures in the impoundment. If oxygen concentrations are a main driver of decomposition rates, lower …

Vocal Analysis Of The Newly Described Atlantic Coast Leopard Frog, Carrie J. Kosiba

Senior Honors Theses and Projects

Urbanization alters animal behaviors and especially impacts amphibians due to their sensitivity to environmental change, small home ranges, and reliance on acoustic communication to locate mates. A newly discovered leopard frog species, Rana kauffeldi, was recently described from the New York City metro area. This species was previously characterized as R. sphenocephala due to their nearly identical morphology, but the two species are distinguished based on genetics and calling characteristics. The goal of this project was to document calling intensity and phenology (timing) differences between urban and rural populations of R. kauffeldi, as well as describe variation across …

How To Vocally Train Transgender Singers: A Thorough Literature Review, Sydney A. Timmer

Senior Honors Theses and Projects

The knowledge of training transgender voices is just beginning to make its way into mainstream music education. However, there needs to be more known and a curriculum in place to address this critical topic. Transgender students face many unique challenges in the voice studio, and educators must have the knowledge to teach these students. There are several elements to consider when training transgender students. These elements include the anatomical changes of masculinizing hormones on the body and voice, the anatomical changes of feminizing hormones on the body and voice, vocal exercises for both transfeminine and transmasculine students, how to choose …

Transition To Race-Free Egfr Formula At Lvhn: Quantitative Analysis Of Impact On Ckd Classification And Management Among African Americans, Frank Lee, Amy Slenker Md, Sharon E. Maynard Md

USF-LVHN SELECT

No abstract provided.

Vermin Of Proof: Arguments For The Admissibility Of Animal Model Studies As Proof Of Causation In Toxic Tort Litigation, Kristen Ranges, Jessica Owley

Articles

Toxic torts is a body of law that aims to compensate individuals for harms they suffer from exposure to hazardous substances. To successfully bring a toxic tort claim, a plaintiff must prove the main elements of a general tort cause of action: duty, breach, causation, and damages. Causation in a toxic tort case is particularly challenging to prove given the nature of toxic substances. To prove the toxicant in question caused the damages alleged, plaintiffs often present expert testimony based on scientific studies. Animal model studies, in particular, can help factfinders understand the health implications of the toxicants at issue. …

An Analysis Of The Use Of The Terms Sex And Gender In Research Reported In Nursing Journals, John R. Blakeman, Valentina M. Fillman

Faculty Publications - Mennonite College of Nursing

Accurately measuring and reporting the demographic characteristics of research participants are imperative to provide consumers of research with an understanding of who was included in a study. While researchers often, incorrectly, use the variables sex and gender interchangeably, these 2 variables are different. We conducted a content analysis of 239 randomly selected research articles, with the purpose of describing how researchers have used sex and gender in studies published in nursing journals and identifying opportunities for improved clarity and precision in measuring these 2 variables. We found that significant improvement is needed in the way these variables are used/reported.

Basic Psychological Needs Satisfaction, Autonomy Support, And Mindsets As Predictors Of Self-Regulation In University Online Learners, Ting Jin

Dissertations

Problem

In contrast to more traditional learning environments, it can be difficult to "see and hear" both the instructor and, more crucially, the students when engaging in online education. This has been one of the most common criticisms leveled against online education for a long time. The COVID-19 disruption and transformation of online learning in higher education underlines the fact that variance among online learners in terms of academic success and psychological well-being are determined by the level and quality of self-regulation. What is the degree of self-regulation among American university students who study online because of the COVID-19 pandemic's …

Land Grant Report 2020-2021, Tennessee. Higher Education Commission.

Land Grant Funding Report

No abstract provided.

Articulation And Transfer In Tennessee Higher Education 2021 Report, Tennessee. Higher Education Commission.

Academic Programs and Workforce Reports

No abstract provided.

Academic Supply And Occupational Demand Report 2021, Tennessee. Higher Education Commission.

Academic Programs and Workforce Reports

No abstract provided.

Beginnings, Elizabeth Becker

Dance (MFA) Theses

Researcher Elizabeth Becker uses personal experiences of pregnancy alongside scholarly research on the developmental movement patterns of the human embryo, fetus, and newborn’s first year of life to explore the multiplicity of these movement patterns within and outside the womb. Becker explores the relationship between the fertilization, germinal, embryonic, and fetal stages in relation to a newborn and its mother. These movement patterns within the beginning stages of life are valuable to research because they simulate neurodevelopmental patterns, which help wire the central nervous system in early childhood. These movements also help lay the foundation for sensory-motor development and life-long …

An Integrated Computational Pipeline To Construct Patient-Specific Cancer Models, Daniel Plaugher

Theses and Dissertations--Mathematics

Precision oncology largely involves tumor genomics to guide therapy protocols. Yet, it is well known that many commonly mutated genes cannot be easily targeted. Even when genes can be targeted, resistance to therapy is quite common. A rising field with promising results is that of mathematical biology, where in silico models are often used for the discovery of general principles and novel hypotheses that can guide the development of new treatments. A major goal is that eventually in silico models will accurately predict clinically relevant endpoints and find optimal control interventions to stop (or reverse) disease progression. Thus, it is …

Design Of A Wearable Multi-Sensory Based Chest Belt Integrated With Iot Functions For Respiration Monitoring, Gozde Cay

Open Access Dissertations

The world is witnessing a rising number of preterm infants who are at significant risk of medical conditions. This situation demands innovative solutions for medical monitoring in the Neonatal Intensive Care Unit (NICU). Medical parameters such as heart rate (HR), respiration rate (RR), and blood oxygen level (SpO₂) are continuously monitored in premature infants in the NICU using a set of wired, sticky electrodes attached to the body. Even though medical adhesives are used, they are still harmful for preterm babies’ underdeveloped skin. Also, development of an accurate and sophisticated technology to monitor respiration rate is a …

Regulation Of Composition And Functions Of Swi/Snf Chromatin Remodeling Complex, Kathleen Diep Tran

Open Access Dissertations

The multi-subunit chromatin remodeler, SWI/SNF, is evolutionarily conserved from yeast to humans. The general function of this remodeler is in gene regulation and manipulation of chromatin architecture. In yeast, SWI/SNF acts upon only a subset of genes but under stress conditions, SWI/SNF is targeted to a greater set of genes. The human SWI/SNF has vital roles in cell differentiation, development, and cellular processes and variations of the complex can exist across tissues and cells. SWI/SNF is recruited to chromatin via two methods: covalent modifications of histones and interaction with transcription factors. Specific subunits of the complex contain domains that can …

What Is The Sound Of Holiness? The Regulation Of Sound And Silence In Early Medieval Monastic Communities, 600-900, Melissa Kapitan

Theses and Dissertations--History

This dissertation explores how the regulation of sound and silence in the early medieval monastery formed a distinct soundscape imbued with personal, communal, and theological resonances. More narrowly, this investigation focuses on the Frankish empire of the ninth century, which saw a series of monastic reforms led by the Carolingian royal family and ecclesiastical figures and consolidated in imperial legislation and treatises on the monastic life.

These ninth-century reforms witnessed not only the promotion of a single rule and custom to guide monastic life, but also a great flowering of liturgical texts, including the earliest treatises on musical theory. These …

Cover And Contents

Turkish Journal of Physics

No abstract provided.

Deletion Of Period Genes Exacerbates Diet-Induced Obesity In Female, But Not Male, Mice, Elizabeth Kantra

Theses and Dissertations--Biology

Sex differences in obesity in mice are mediated by differential responses of circadian rhythms to high-fat feeding in males and females. Other studies also showed circadian Period genes regulate diet-induced obesity in mice. In this study, we investigated the role of the Period genes in regulating sex differences in obesity. Male and female C57BL/6J wild type, Per1/2 KO, and Per1/2/3 KO mice were housed in 12L:12D and fed high-fat diet for 12 weeks. We found a striking sex difference in obesity such that disabling the Period genes exacerbated adiposity in female, but not male, mice. Increased adiposity in female Period …

Understanding The Effects Of Embryonic Hyperglycemia On Retinal Development And Maintenance, Kayla Titialii-Torres

Theses and Dissertations--Biology

Hundreds of millions of people are affected by diabetes worldwide. Whether they are diagnosed with prediabetes or Type I or II diabetes, there are a variety of mechanisms in the pathogenesis of diabetes. Diabetes is a disease which consists of recurring states of hyperglycemia that can be difficult to manage due to either lack of insulin production or improper utilization of insulin. While these mechanisms of action differ, complications induced by diabetes occur in both poorly regulated Type I and II. Common complications of diabetes include nerve damage, kidney damage, and eye damage. Eye damage specifically is called diabetic retinopathy …

Identifying Epidermal Enriched Genes Required For Planarian Regeneration- Sp. Schmidtea Mediterranea, Pallob Barai

Theses and Dissertations--Biology

The outer epithelial layer covering an organism, commonly known as the epidermis, is crucial for maintaining homeostasis and for the wound healing processes after injury. The planarian epidermis allows flatworms to heal their wounds and virtually restore any missing tissues. Immediately after amputation, planarians contract their muscle and stretch their epidermis to heal the wound area. However, how the planarian epidermis coordinates with other tissues and mechanisms after the initial wound healing processes begins is not understood in detail. I hypothesized that epidermal cell stretching upon wound healing induces transcriptional changes that are required for effective regeneration. To test this …

Assessing Ear Pinna Repair In The Mrl/Mpj Mouse Strain, Fatemeh Safaee

Theses and Dissertations--Biology

The outcome of tissue repair varies across species. Vertebrates such as salamanders have the ability to not only heal scar-free but also completely regenerate lost appendages. In contrast, most mammals heal their wounds with fibrotic scarring. Understanding the key drivers of these divergent injury responses remains a major unanswered question in animal biology. Previous work with the Murphy’s Roth Large (MRL/MpJ) inbred mouse strain suggested they have the ability to rapidly close small (2mm) ear holes. While this ability was originally published as an example of regeneration, subsequent work by other groups suggested that it might represent something more akin …

The Role Of Protein Tyrosine Phosphatase Receptor Type F In Intestinal Homeostasis And Colorectal Cancer, Ashley T. Skaggs

Theses and Dissertations--Molecular and Cellular Biochemistry

Protein phosphorylation defines one of the most important regulatory mechanisms in cell signaling. PTPRF, protein tyrosine phosphatase receptor type F, belongs to the class I R2A subfamily of protein tyrosine phosphatases (PTP). The overall objective of this dissertation is to investigate the molecular mechanisms by which PTPRF regulates normal and cancer stem cells by controlling Wnt signaling.

Dysregulation of Wnt signaling promotes the initiation and progression of colorectal cancer (CRC). We first determined the functional important of PTPRF in regulating Wnt signaling in CRC. Combining cell culture, 3D tumor organoid and xenograft models, results from our study establish PTPRF as …

A Multidisciplinary Characterization Of The Enzymology And Biology Of Reversible Glucan Phosphorylation In Toxoplasma Gondii , Robert Murphy

Theses and Dissertations--Molecular and Cellular Biochemistry

Toxoplasma gondii is an opportunistic, protozoan parasite of all warm-blooded animals, infecting roughly one-third of humans worldwide. Humans acquire infections by consuming T. gondii tissue cysts in undercooked meat or from oocysts shed in cat feces. Encysted parasites convert into rapidly growing tachyzoites that disseminate throughout the body, defining the acute phase of infection. Under host immune pressure, tachyzoites convert into bradyzoites that populate tissue cysts found in CNS or muscle tissue and persist for the lifetime of the host, defining the chronic phase of infection. Tissue cysts are responsible for transmission via carnivory, but also possess the ability to …

Defining Patient Cohorts For Guiding Clinical Trials And Treatment In Lafora Disease: A Model For The Rare Disease Community, Katherine Janae Donohue

Theses and Dissertations--Molecular and Cellular Biochemistry

In the US, approximately 8000 rare diseases have been identified. Combined, rare diseases impact more than 30 million people in the U.S. alone, with 75% of those being children. However, research, funding, and therapeutic development for the rare disease community remains challenging because of the incredible diversity – not only between diseases, but often even within a single disease.

LD is an ultra-rare childhood dementia and epilepsy caused by mutations in one of two driver genes: EPM2A, which encodes for the glycogen phosphatase laforin, and EPM2B/NHLRC1, which encodes the E3 ubiquitin ligase malin. Children with LD …

Simple Control For Complex Pandemics, Sarah C. Fay, Dalton J. Jones, Munther A. Dahleh, A.E. Hosoi

Engineering: Faculty Publications

he COVID-19 pandemic began over two years ago, yet schools, businesses, and other organiza- tions are still struggling to keep the risk of disease outbreak low while returning to (near) normal functionality. Observations from these past years suggest that this goal can be achieved through the right balance of mitigation strategies, which may include some combination of mask use, vac- cinations, viral testing, and contact tracing. The choice of mitigation measures will be uniquely based on the needs and available resources of each organization. This article presents practical guidance for creating these policies based on an analytical model of disease …

Tirso De Molina’S El Melancólico And The Performative Authenticity Of Early Modern (Pseudo-)Melancholy, Paul Michael Johnson

Global Language Studies Faculty publications

La melancolía se ha convertido casi en sinónimo de la temprana modernidad, no ya como una aflicción crónica de la psicología médica, sino como un sentimiento definitorio del periodo en términos generales. Esto es de aplicación especial para el caso de España, cuya reputación como creadora de melancólicos fue legendaria dentro y fuera de sus fronteras. Recientemente se ha dudado sobre su autenticidad, y los estudiosos han cuestionado cuánto en esa melancolía era condición psicológica, o bien moda pasajera, obsesión auto-creada, histeria colectiva imaginada o performance dramática. Este ensayo analiza las implicaciones mutuas de la melancolía y la incertidumbre en …

Coming Of Age In Post-Climate Change Florida In Karen Russell's "The Gondoliers", Christopher Nank

The Marjorie Kinnan Rawlings Journal of Florida Literature

No abstract provided.

The Case For Alternate Media Requirement Expressions In Systems Engineering, Jason Kolligs

Dissertations

“Requirements” are often presented as a necessary, if not mandated, component or tool of the systems engineering process. Despite their place in engineering, low quality requirements are the first potential mistakes of an engineering project and their effects are potentially felt downstream in the form of increased costs and schedule overruns. Innovations to improve requirements engineering have historically omitted the requirement media. This research provides the rationale and process heuristics to include alternate media requirement expressions within systems engineering which shifts accountability to higher context requirement expressions that may require less cognitive load while decreasing effort and schedule thereby potentially …