Digital Commons Network^™

An Investigation Of The Sociality And Behaviour Of Captive Polar Bears Housed In Bachelor Groups, A Cavalleri, A Bell, K Wilkins, J Brereton, R Preziosi, Pastorino G Quintavalle

School of Biological and Marine Sciences

The polar bear (Ursus maritimus) is a popular and easily recognisable species and has a long history of being housed in zoological collections. However, due to concerns regarding space requirements and welfare, many zoos have since removed this species from their collection plans. Polar bears require spacious enclosures with considerable amounts of enrichment and are susceptible to stereotypy if their needs are not met. Yorkshire Wildlife Park, UK, has set up a large enclosure to demonstrate best-practice care of polar bears. Observations of four male captive polar bears were conducted at the collection, to investigate behaviour and sociality between the …

Expandable Intervertebral Cage, Kamran Aghayev, James J. Doulgeris, Sabrina A. Gonzalez Blohm, Frank D. Vrionis

USF Patents

A method and system for performing bone fusion and/or securing one or more bones, such as adjacent vertebra, are disclosed.

29 M 6 A-Rna Methylation (Epitranscriptomic) Regulators Are Regulated In 41 Diseases Including Atherosclerosis And Tumors Potentially Via Ros Regulation - 102 Transcriptomic Dataset Analyses, Ming Liu, Keman Xu, Fatma Saaoud, Ying Shao, Ruijing Zhang, Yifan Lu, Yu Sun, Charles Drummer Iv, Li Li, Sheng Wu, Satya P Kunapuli, Gerard J Criner, Jianxin Sun, Huimin Shan, Xiaohua Jiang, Hong Wang, Xiaofeng Yang

Center for Translational Medicine Faculty Papers

We performed a database mining on 102 transcriptomic datasets for the expressions of 29 m6A-RNA methylation (epitranscriptomic) regulators (m6A-RMRs) in 41 diseases and cancers and made significant findings: (1) a few m6A-RMRs were upregulated; and most m6A-RMRs were downregulated in sepsis, acute respiratory distress syndrome, shock, and trauma; (2) half of 29 m6A-RMRs were downregulated in atherosclerosis; (3) inflammatory bowel disease and rheumatoid arthritis modulated m6A-RMRs more than lupus and psoriasis; (4) some organ failures shared eight upregulated m6A-RMRs; end-stage renal failure (ESRF) downregulated 85% of m6A-RMRs; (5) Middle-East respiratory syndrome coronavirus infections modulated m6A-RMRs the most among viral infections; …

Independent - Feb. 15, 2022, Monty Stites

The Independent (1988-present)

No abstract provided.

Micelles Inhibit Electro-Oxidation Degradation Of Nonylphenol Ethoxylates, Yangyuan Ji, Junfeng Niu, Yuhang Fang, Alliyan Tan Nou, David M. Warsinger

School of Mechanical Engineering Faculty Publications

Nonylphenol ethoxylates (NEPOs) are widely used as nonionic surfactant in the industry, which pose a threat to environment and human health. In this study, we conducted kinetic experiments and chemical analysis to investigate the effects of NEPOs micelles on degradation kinetics and electro-oxidation degradation mechanism. The electro-oxidation degradation of NEPOs followed pseudo-first order kinetics and more than 92% of NEPOs was degraded. Furthermore, the hydroxyl radicals generated by the Ti4O7 anode contributed to 41% of degradation performance. During the entire degradation process, the micelles of NEPOs undergo growth, and the steric hindrance phenomenon of micelles prevents NEPOs from being attack …

Biogeosciences Perspectives On Integrated, Coordinated, Open, Networked (Icon) Science, D. Dwivedi, A. L. D. Santos, M. A. Barnard, T. M. Crimmins, A. Malhotra, K. A. Rod, K. S. Aho, S. M. Bell, B. Bomfim, F. Q. Brearley, H. Cadillo-Quiroz, J. Chen, C. M. Gough, E. B. Graham, C. R. Hakkenberg, L. Haygood, G. Koren, E. A. Lilleskov, L. K. Meredith, S. Naeher, Z. L. Nickerson, O. Pourret, H.-S. Song, M. Stahl, N. Taş, R. Vargas, S. Weintraub-Leff

Department of Food Science and Technology: Faculty Publications

This article is composed of three independent commentaries about the state of Integrated, Coordinated, Open, Networked (ICON) principles in the American Geophysical Union Biogeosciences section, and discussion on the opportunities and challenges of adopting them. Each commentary focuses on a different topic: (a) Global collaboration, technology transfer, and application (Section 2), (b) Community engagement, community science, education, and stakeholder involvement (Section 3), and (c) Field, experimental, remote sensing, and real-time data research and application (Section 4). We discuss needs and strategies for implementing ICON and outline short- and long-term goals. The inclusion of global data and international …

A Novel Non‑Selective Atypical Pkc Agonist Could Protect Neuronal Cell Line From A Β ‑Oligomer Induced Toxicity By Suppressing A Β Generation, Dongmei Zou, Qian Li, Wenyang Pan, Peng Chen, Miao Sun, Xiaofeng Bao

Publications and Research

Atypical protein kinase C (aPKCs) serve key functions in embryonic development by regulating apical-basal polarity. Previous studies have shed light on their roles during adulthood, especially in the development of Alzheimer's disease (AD). Although the crystal structure of PKCι has been resolved, an agonist of aPKCs remains to be discovered. In the present study, by using the Discovery Studio program and LibDock methodology, a small molecule library (K66-X4436 KINA Set) of compounds were screened for potential binding to PKCι. Subsequently, the computational docking results were validated using affinity selection-mass spectrometry, before in vitro kinase activity was used to determine the …

The Prospector, February 15, 2022, Utep Student Publications

The Prospector

Headline: Natalicio's Legacy

Fully Resolved Assembly Of Cryptosporidium Parvum, Vipin K Menon, Pablo C Okhuysen, Cynthia L Chappell, Medhat Mahmoud, Medhat Mahmoud, Qingchang Meng, Harsha Doddapaneni, Vanesa Vee, Yi Han, Sejal Salvi, Sravya Bhamidipati, Kavya Kottapalli, George Weissenberger, Hua Shen, Matthew C Ross, Kristi L Hoffman, Sara Javornik Cregeen, Donna M Muzny, Ginger A Metcalf, Richard A Gibbs, Joseph F Petrosino, Fritz J Sedlazeck

Faculty, Staff and Student Publications

BACKGROUND: Cryptosporidium parvum is an apicomplexan parasite commonly found across many host species with a global infection prevalence in human populations of 7.6%. Understanding its diversity and genomic makeup can help in fighting established infections and prohibiting further transmission. The basis of every genomic study is a high-quality reference genome that has continuity and completeness, thus enabling comprehensive comparative studies.

FINDINGS: Here, we provide a highly accurate and complete reference genome of Cryptosporidium parvum. The assembly is based on Oxford Nanopore reads and was improved using Illumina reads for error correction. We also outline how to evaluate and choose from …

Cell Specific Peripheral Immune Responses Predict Survival In Critical Covid-19 Patients, Junedh M Amrute, Alexandra M Perry, Gautam Anand, Carlos Cruchaga, Karl G Hock, Christopher W Farnsworth, Gwendalyn J Randolph, Kory J Lavine, Ashley L Steed

Open Access Publications

SARS-CoV-2 triggers a complex systemic immune response in circulating blood mononuclear cells. The relationship between immune cell activation of the peripheral compartment and survival in critical COVID-19 remains to be established. Here we use single-cell RNA sequencing and Cellular Indexing of Transcriptomes and Epitomes by sequence mapping to elucidate cell type specific transcriptional signatures that associate with and predict survival in critical COVID-19. Patients who survive infection display activation of antibody processing, early activation response, and cell cycle regulation pathways most prominent within B-, T-, and NK-cell subsets. We further leverage cell specific differential gene expression and machine learning to …

A Diffusion Mri-Based Spatiotemporal Continuum Of The Embryonic Mouse Brain For Probing Gene-Neuroanatomy Connections, Dan Wu, Linda J Richards, Zhiyong Zhao, Zuozhen Cao, Wanrong Luo, Wei Shao, Song-Hai Shi, Michael I Miller, Susumu Mori, Seth Blackshaw, Jiangyang Zhang

Open Access Publications

The embryonic mouse brain undergoes drastic changes in establishing basic anatomical compartments and laying out major axonal connections of the developing brain. Correlating anatomical changes with gene-expression patterns is an essential step toward understanding the mechanisms regulating brain development. Traditionally, this is done in a cross-sectional manner, but the dynamic nature of development calls for probing gene-neuroanatomy interactions in a combined spatiotemporal domain. Here, we present a four-dimensional (4D) spatiotemporal continuum of the embryonic mouse brain from E10.5 to E15.5 reconstructed from diffusion magnetic resonance microscopy (dMRM) data. This study achieved unprecedented high-definition dMRM at 30- to 35-µm isotropic resolution, …

The Cynics' Understanding Of And Contribution To Philosophy, Yossra Hamouda

Theses and Dissertations

The Cynics are an understudied school in the history of philosophy especially, if we compare the amount of literature written on the Cynics to the amount of literature written on Socrates, Plato, Aristotle and other Greek schools like the Epicureans, the Neo-Platonists and even the Stoics. The lack of research interest in the Cynics, both from the side of philosophers and historians, is possibly grounded in a lack of interest in understanding the Cynical conception of philosophy. Unless we take a serious interest in understanding the Cynical conception of philosophy, we risk reducing the Cynics to the historical clowns of …

Animal Abuse In Egypt: An Assessment Of Attitudes, Behaviors And Protective Factors Among University Students And Graduates., Salma El Saedy

Theses and Dissertations

Animal abuse is an understudied problem in Egypt with possible ramifications on both non-human and human animals and links to interpersonal violence and conduct problems. This study aims to explore the attitudes and behaviors of Egyptian university students and graduates towards the treatment and use of animals in society and to test if exposure to animal abuse is associated with abusive behavior. The study also aims to identify possible protective factors against animal abuse among a group of positive deviants. A mixed-methods approach was used to study these questions; an online survey was disseminated over social media platforms, and 99 …

Fully Resolved Assembly Of Cryptosporidium Parvum, Vipin K Menon, Pablo C Okhuysen, Cynthia L Chappell, Medhat Mahmoud, Medhat Mahmoud, Qingchang Meng, Harsha Doddapaneni, Vanesa Vee, Yi Han, Sejal Salvi, Sravya Bhamidipati, Kavya Kottapalli, George Weissenberger, Hua Shen, Matthew C Ross, Kristi L Hoffman, Sara Javornik Cregeen, Donna M Muzny, Ginger A Metcalf, Richard A Gibbs, Joseph F Petrosino, Fritz J Sedlazeck

Faculty, Staff and Students Publications

BACKGROUND: Cryptosporidium parvum is an apicomplexan parasite commonly found across many host species with a global infection prevalence in human populations of 7.6%. Understanding its diversity and genomic makeup can help in fighting established infections and prohibiting further transmission. The basis of every genomic study is a high-quality reference genome that has continuity and completeness, thus enabling comprehensive comparative studies.

FINDINGS: Here, we provide a highly accurate and complete reference genome of Cryptosporidium parvum. The assembly is based on Oxford Nanopore reads and was improved using Illumina reads for error correction. We also outline how to evaluate and choose from …

Enhanced Anticancer Activity Of Nedaplatin Loaded Onto Copper Nanoparticles Synthesized Using Red Algae, Nada Mostafa Aboeita, Sherif Ashraf Fahmy, Mayyada M. H. El-Sayed, Hassan Mohamed El-Said Azzazy

Faculty Journal Articles

Marine algae are a rich source of biologically active compounds that can be utilized in various food and pharmaceutical applications. In this study, ultrasound-assisted extraction (UAE) was optimized to maximize yield and total carbohydrate content extracted from the red algae, Pterocladia capillacea. The extract was shown to possess potent antioxidant activity of up to ~70%, and was successfully used as a reducing and capping agent in the green synthesis of copper nanoparticles, which were characterized by UV-spectroscopy, Fourier transform infrared (FTIR) spectroscopy, X-ray diffraction (XRD), transmission electron microscopy (TEM), and dynamic light scattering (DLS). Primarily, CuO nanoparticles with an average …

Therapeutic Efficacy Of 177lu-Labeled A20fmdv2 Peptides Targeting Ανβ6, Truc Thao Huynh, Sreeja Sreekumar, Cedric Mpoy, Buck Edward Rogers

2020-Current year OA Pubs

Integrin α

Covid-19 Newsletter (Vol. 106), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Fusarium And Verticillium Wilts Of Vegetables, Nick Volesky, Marion Murray, Claudia Nischwitz

All Current Publications

Fusarium wilt and Verticillium wilt are soilborne plant diseases that attack vascular tissue. They cause similar symptoms in their hosts and are difficult to manage as they can survive in the soil for many years. Once a plant is infected, there is no treatment or cure. Therefore, management should focus on preventive and cultural control practices. This fact sheet identifies the many vegetables susceptible to these pathogens in Utah and reviews symptoms, diagnosis, and ways to prevent these diseases.

Butterfly Eyespots Evolved Via Cooption Of An Ancestral Gene-Regulatory Network That Also Patterns Antennae, Legs, And Wings, Suriya Narayanan Murugesan, Heidi Connahs, Yuji Matsuoka, Mainak Das Gupta, Galen J. Tiong, Manizah Huq, Thomas Werner, Et. Al.

Michigan Tech Publications, Part 1

Butterfly eyespots are beautiful novel traits with an unknown developmental origin. Here we show that eyespots likely originated via cooption of parts of an ancestral appendage gene-regulatory network (GRN) to novel locations on the wing. Using comparative transcriptome analysis, we show that eyespots cluster most closely with antennae, relative to multiple other tissues. Furthermore, three genes essential for eyespot development, (), (), and (), share similar regulatory connections as those observed in the antennal GRN. CRISPR knockout of -regulatory elements (CREs) for and led to the loss of eyespots, antennae, legs, and also wings, demonstrating that these CREs are highly …

Hydraulic Permeability And Compressive Properties Of Porcine And Human Synovium, Milad Rohanifar, Benjamin B Johnston, Alexandra L Davis, Young Guang, Kayla Nommensen, James A J Fitzpatrick, Christine N Pham, Lori A Setton

2020-Current year OA Pubs

The synovium is a multilayer connective tissue separating the intra-articular spaces of the diarthrodial joint from the extra-synovial vascular and lymphatic supply. Synovium regulates drug transport into and out of the joint, yet its material properties remain poorly characterized. Here, we measured the compressive properties (aggregate modulus, Young's modulus, and Poisson's ratio) and hydraulic permeability of synovium with a combined experimental-computational approach. A compressive aggregate modulus and Young's modulus for the solid phase of synovium were quantified from linear regression of the equilibrium confined and unconfined compressive stress upon strain, respectively (H

Being Brave: Easier Than It Sounds, Aren E. Gerdon

Teaching and Learning Together in Higher Education

No abstract provided.

Belonging In Biology: Working Through Pedagogical Partnership For Social Justice In Stem, Angelina Latin

Teaching and Learning Together in Higher Education

No abstract provided.

Launching The Community Learning And Inclusivity Partnership (Clip) Program At Emmanuel College, Anupama Seshan

Teaching and Learning Together in Higher Education

No abstract provided.

Launching A Pedagogical Partnership Program At Emmanuel College, Nandeeta Bala

Teaching and Learning Together in Higher Education

No abstract provided.

Podiatric Medicine And Surgery Journal Club, Tyler Coye, Courtney Foote, Aaren Harrington, Ryan Thurston, Eileen Farley, Gaurav Singh

Advances in Clinical Medical Research and Healthcare Delivery

The general purpose of this and future journal club columns is to facilitate the review of specific research studies and to discuss implications of each study for clinical practice as it relates to the lower extremity. Each column will be dedicated to a specific topic relevant to the treatment of a Foot and Ankle pathology. Each article chosen and reviewed will reflect the most recent advancements in Foot and Ankle Surgery and Medicine. We hope that you, the reader, find value and pleasure in the articles reviewed.

Challenging Times In Academia, Editorial Board

Spora: A Journal of Biomathematics

With volume 8, Spora is well on its way to be a highly respected platform for student-driven research in mathematics, biology, and related fields. Spora's role in disseminating work especially accessible to students makes this journal a unique platform to expand the body of knowledge in mathematical biology. Spora welcomes submissions related to Ph.D. dissertations, master's theses, and undergraduate research projects.

Silage Preparation And Fermentation Characteristics Of Pearl Millet Stover Treated With Microbial Additive In West Africa, Y. Cai, Z. Du, S. Yamasaki, D. Jethro, M. Nignan

IGC Proceedings (1977-2023)

Pearl millet (Pennisetum glaucum L.) stover is one of the main crop by-products in West Africa. To effectively use the crop by-product resources as roughage for ruminant to cover the feed shortage in the dry season, the millet stover silage was prepared using laboratory-scale fermentation system without (control) or with lactic acid bacteria inoculant (LP, Lactobacillus plantarum) and cellulase enzyme (AC, Acremonium) in Burkina Faso, and their fermentation characteristics and chemical composition were analyzed. The dry matter (DM) of fresh millet before ensiling was 44.3%, and their organic matter, crude protein (CP), ether extract, neutral detergent fiber …

Seasonal Patterns Of Herbage Accumulation Dynamics In Marandu Palisadegrass Subjected To Intensities Of Continuous Stocking Management, André F. Sbrissia, Daniel Schmitt, Paulo G. Duchini, Sila C. Da Silva

IGC Proceedings (1977-2023)

It is relatively well reported in the literature that pastures can have similar forage net accumulation when managed with contrasting structures. However, we hypothesized that the patterns of forage accumulation dynamics of pastures managed at different canopy heights is dependent on environmental conditions. The experimental treatments were four canopy heights (10, 20, 30, and 40 cm), allocated to experimental units according to a randomized complete block design with four replicates and evaluated throughout four contrasting environmental seasons (Summer, Autumn, Winter-Early Spring, and Late Spring). Under favourable growing conditions greater forage accumulation was observed in pastures maintained taller; on the contrary, …

Screening Of Napier Grass (Pennisetum Purpureum Schumac.) Clones For Stunt Disease In Western Kenya, Caroline A. O. Kute

IGC Proceedings (1977-2023)

Napier stunt disease (NSD) is a threat to Napier grass farming in the smallholder dairy industry in east and central Africa. NSD in Kenya is caused by Candidatus Phytoplasma oryzae (Ns-phytoplasma) belonging to the 16SrXI group; vectored by a leaf hopper Maiestas banda. The objective of the study was to determine the incidence (proportion of diseased leaves) and severity (proportion of leaf area diseased [PLAD]) of stunt disease in Napier clones by screening in Bungoma, Kakamega and Busia Counties in Western Kenya. The Napier clones were germplasm collections maintained at KALRO Kitale and Muguga nurseries and in farmers’ fields. …

Revisiting Nitrogen Fertilisation Rates Of Kikuyu And Kikuyu-Ryegrass Pastures, C. Viljoen, Janke Van Der Colf, Pieter A. Swanepoel

IGC Proceedings (1977-2023)

Irrigated pastures are used for dairy production in South Africa. Minimum-tillage and nitrogen (N) fertilisation are important management practices for kikuyu (Pennisetum clandestinum) and ryegrass (Lolium spp.) pastures. Nitrogen fertiliser application rates as high as 500 kg N ha^-1 year^-1 have been reported. Conventional tillage as well as cutting and removal of herbage material (opposed to removal through grazing) are the basis on which these fertiliser guidelines were developed. The current management practices have substantially changed the soil organic carbon and N stoichiometry. The aim of this study was to determine an optimum rate of …