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2022

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The First Report Of Lissomus Dalman (Coleoptera: Elateridae: Lissominae) From The Greater Antilles, With Two New Species From The Dominican Republic, Paul J. Johnson Feb 2022

The First Report Of Lissomus Dalman (Coleoptera: Elateridae: Lissominae) From The Greater Antilles, With Two New Species From The Dominican Republic, Paul J. Johnson

Insecta Mundi

Lissomus quisqueya new species and L. woodruffi new species are described. Both species are reported from the Dominican Republic on the island of Hispaniola. These are the first species of Lissomus Dalman reported from the Greater Antilles. Lissomus quisqueya is recorded from montane mesic forests in the Cordillera Central from Dajadon and La Vega provinces. Lissomus woodruffi is recorded from Barahona, Independencia and Pedernales provinces from montane mesic forest in the Sierra de Bahoruco. Morphologically, these species are most similar to members of the L. discedens Bonvouloir species group from Mesoamerica and South America. Known sites of occurrence of L. …


A Third Species Of Haroldiellus Gordon And Skelley, 2007 From Mexico And Central America (Coleoptera: Scarabaeidae: Aphodiinae: Aphodiini), Paul E. Skelley, Oliver Keller Feb 2022

A Third Species Of Haroldiellus Gordon And Skelley, 2007 From Mexico And Central America (Coleoptera: Scarabaeidae: Aphodiinae: Aphodiini), Paul E. Skelley, Oliver Keller

Insecta Mundi

Haroldiellus woodruffi Skelley and Keller, new species, (Coleoptera: Scarabaeidae: Aphodiinae: Aphodiini), from Costa Rica, Guatemala, Mexico, and Panama is described. An updated key for the genus, updated distributions, and diagnoses for the other two species are provided.

Se describe la nueva especie Haroldiellus woodruffi Skelley y Keller (Coleoptera: Sacarabaeidae: Aphodiinae: Aphodiinae) de Costa Rica, Guatemala, México y Panamá. Se provee una clave, distribuciones y diagnosis actualizadas para las otras dos especies.

Worldwide, the scarabaeid subfamily Aphodiinae Leach, 1815 (when including Aegialiinae Laporte, 1840) con­sists of about 3200 species in 14 tribes and around 280 genera (Nikolajev 2008; Skelley 2008; …


A New Species Of Phyllophaga Harris (Coleoptera: Scarabaeidae: Melolonthinae) From Puerto Rico, Kyle E. Schnepp Feb 2022

A New Species Of Phyllophaga Harris (Coleoptera: Scarabaeidae: Melolonthinae) From Puerto Rico, Kyle E. Schnepp

Insecta Mundi

Phyllophaga bobevelynorum Schnepp, new species (Coleoptera: Scarabaeidae: Melolonthinae), is described from Puerto Rico. The species is illustrated and diagnosed, and a checklist of the species in Puerto Rico is given.

The genus Phyllophaga Harris is extremely diverse, with over 850 species currently assigned to it, all occurring in the New World. As with almost all Phyllophaga in the West Indies, this new species belongs to the subgenus Cne­marachis Saylor, whose members have the outer surface of the metatibia with an incomplete carina. As discussed by Smith and Paulsen (2015), this subgenus is endemic to the West Indies and has a …


A New Genus Of Predatory Midge In The Monohelea Complex From Eocene Baltic Amber (Diptera: Ceratopogonidae), Ryszard Szadziewski, William L. Grogan Jr., Elżbieta Sontag, Błażej Bojarski Feb 2022

A New Genus Of Predatory Midge In The Monohelea Complex From Eocene Baltic Amber (Diptera: Ceratopogonidae), Ryszard Szadziewski, William L. Grogan Jr., Elżbieta Sontag, Błażej Bojarski

Insecta Mundi

Monogedania, a new fossil monotypic genus of predatory midge (Diptera: Ceratopogonidae) is described from Eocene Baltic amber and its position within the Monohelea complex is discussed. We dis­covered that the membranous portion of the aedeagus is extended in Monogedania clunipes (Loew), new combination, which suggests that the aedeagus of some extinct predatory midges can be penis-like. The Eocene Monohelea baltica Szadziewski, is transferred to the genus Schizohelea Kieffer, new combination, and, the previously unknown female is described, and key characters are included in color photographs of its entire habitus, head, distal hind tarsomeres and claws.

The Monohelea …


Extinct Or Extant? A New Species Of Termitodius Wasmann, 1894, (Coleoptera: Scarabaeidae: Aphodiinae: Rhyparini) With A Short Review Of The Genus, Paul E. Skelley, Julian Clavijo-Bustos, Oliver Keller Feb 2022

Extinct Or Extant? A New Species Of Termitodius Wasmann, 1894, (Coleoptera: Scarabaeidae: Aphodiinae: Rhyparini) With A Short Review Of The Genus, Paul E. Skelley, Julian Clavijo-Bustos, Oliver Keller

Insecta Mundi

A new species of Termitodius Wasmann (Coleoptera: Scarabaeidae: Aphodiinae: Rhyparini) is de­scribed from Colombia, Termitodius woodruffi Skelley, Clavijo-Bustos, and Keller, new species. This species is both extant and abundantly preserved in copal. The genus Termitodius is reviewed with a key and brief accounts to all species.

Una nueva especie de Termitodius Wasmann (Coleoptera: Scarabaeidae: Aphodiinae: Rhyparini) es descrita de Colombia, Termitodius woodruffi Skelley, Clavijo-Bustos, y Keller, nueva especie. Esta especie es existente y abundantemente preservada en copal. El género Termitodius es revisado con una clave y reseñas breves para todas las especies.

The pantropical tribe Rhyparini is represented …


Dichotomius Woodruffi, A New Dichotomius Species Of The Agenor Group From Costa Rica And Nicaragua (Coleoptera: Scarabaeidae: Scarabaeinae), Ángel Solis, Burt Kohlmann Feb 2022

Dichotomius Woodruffi, A New Dichotomius Species Of The Agenor Group From Costa Rica And Nicaragua (Coleoptera: Scarabaeidae: Scarabaeinae), Ángel Solis, Burt Kohlmann

Insecta Mundi

We describe a new species of Dichotomius Hope, 1838, from the D. agenor species-group from Costa Rica and Nicaragua: D. woodruffi Solís and Kohlmann, new species (Coleoptera: Scarabaeidae: Scara­baeinae). Based on this discovery, we confirm that Dichotomius enioi Montoya-Molina and Vaz-de-Mello, 2021 and D. agenor (Harold, 1869) are not currently distributed in Costa Rica. Instead, the only species of Dichotomius that are currently distributed in Costa Rica from the D. agenor species-group are D. centralis (Harold, 1869) and D. woodruffi. We discuss the distribution of the Dichotomius agenor species-group in Central America.

In …


Variable Anterior Segment Dysgenesis And Cardiac Anomalies Caused By A Novel Truncating Variant Of Foxc1, Mariya R. Ahmed, Saumil Sethna, Laura A. Krueger, Michael B. Yang, Robert B. Hufnagel Feb 2022

Variable Anterior Segment Dysgenesis And Cardiac Anomalies Caused By A Novel Truncating Variant Of Foxc1, Mariya R. Ahmed, Saumil Sethna, Laura A. Krueger, Michael B. Yang, Robert B. Hufnagel

Biology Graduate Research

Anterior segment dysgenesis (ASD) encompasses a wide spectrum of developmental abnormalities of the anterior ocular segment, including congenital cataract, iris hypoplasia, aniridia, iridocorneal synechiae, as well as Peters, Axenfeld, and Rieger anomalies. Here, we report a large five-generation Caucasian family exhibiting atypical syndromic ASD segregating with a novel truncating variant of FOXC1. The family history is consistent with highly variable autosomal dominant symptoms including isolated glaucoma, iris hypoplasia, aniridia, cataract, hypothyroidism, and congenital heart anomalies. Whole-exome sequencing revealed a novel variant [c.313_314insA; p.(Tyr105*)] in FOXC1 that disrupts the α-helical region of the DNA-binding forkhead box domain. In vitro studies …


Helminth Products Modulate Innate Immune Recognition Of Nucleic Acids In Systemic Lupus Erythematosus, Laura B. Dall, Bent Deleuran, Lars Østergaard, Maibritt Mardahl, Paul Denton, Peter Nejsum Feb 2022

Helminth Products Modulate Innate Immune Recognition Of Nucleic Acids In Systemic Lupus Erythematosus, Laura B. Dall, Bent Deleuran, Lars Østergaard, Maibritt Mardahl, Paul Denton, Peter Nejsum

Biology Faculty Publications

Aim

Current treatment of Systemic Lupus Erythematosus (SLE) is suboptimal and causes broad immunosuppression. Therapeutic use of helminths or helminth products has been suggested for autoimmune diseases such as SLE. In the present study, we evaluated possible immunomodulating effects of adult body fluid (ABF) from Ascaris suum on peripheral blood mononuclear cells (PBMCs) from SLE patients in an ex vivo setup.

Methods

PBMCs from SLE patients and healthy controls (HC) were isolated and stimulated ex vivo with ABF and Toll-like receptor agonists or activators of the stimulator of interferon genes (STING) or mitochondrial antiviral signaling protein (MAVS) pathways. After 24 …


Definición De La Dinámica De Problemas, Clarissa Gaona Romero, Katherine Curi-Quinto, Laura Guzmán Abello, Carmen Quinteros-Reyes, Paraskevi Seferidi, Antonio Bernabe-Ortiz, Lindsey Pawlowski, Ellis Ballard Feb 2022

Definición De La Dinámica De Problemas, Clarissa Gaona Romero, Katherine Curi-Quinto, Laura Guzmán Abello, Carmen Quinteros-Reyes, Paraskevi Seferidi, Antonio Bernabe-Ortiz, Lindsey Pawlowski, Ellis Ballard

Social System Design Lab

Las herramientas de dinámica de sistemas nos ayudan a descubrir las estructuras del sistema que producen los problemas que nos importan para que podamos identificar mejores soluciones.Como ilustra esta cita, el primer paso, y posiblemente el más importante, en cualquier proceso de resolución de problemas es definir claramente el problema que se desea resolver. En otras disciplinas científicas, esta definición de un problema puede ser estática, o instantánea, ya que analiza un problema particular en un momento dado. Esto puede parecer un único punto de datos, resultado o evento. En la dinámica de sistemas, sin embargo, definimos los problemas como …


Acumulaciones Y Diagramas De Niveles Y Flujos, Clarissa Gaona Romero, Laura Guzmán Abello, Carmen Quinteros-Reyes, Paraskevi Seferidi, Antonio Bernabe-Ortiz, Lindsey Pawlowski, Ellis Ballard Feb 2022

Acumulaciones Y Diagramas De Niveles Y Flujos, Clarissa Gaona Romero, Laura Guzmán Abello, Carmen Quinteros-Reyes, Paraskevi Seferidi, Antonio Bernabe-Ortiz, Lindsey Pawlowski, Ellis Ballard

Social System Design Lab

Existen varias características de los sistemas complejos que dificultan la creación de cambios en la salud de la comunidad, los cuales incluyen los siguientes: retrasos entre la intervención y el resultado, respuestas inesperadas o confusas a intervenciones, y diferencias en las formas en que los individuos y los grupos experimentan el mismo sistema. El concepto de “acumulación” brinda información importante sobre la forma en que se generan las percepciones erróneas, retrasos y respuestas contradictorias al sistema dentro de los esfuerzo de la salud que se llevan a cabo. Los diagramas de niveles y flujos son herramientas que sirven para identificar …


Iceberg Del Pensamiento Sistémico: Buceando Bajo La Superficie, Clarissa Gaona Romero, Laura Guzmán Abello, Carmen Quinteros-Reyes, Paraskevi Seferidi, Antonio Bernabe-Ortiz, Lindsey Pawlowski, Ellis Ballard Feb 2022

Iceberg Del Pensamiento Sistémico: Buceando Bajo La Superficie, Clarissa Gaona Romero, Laura Guzmán Abello, Carmen Quinteros-Reyes, Paraskevi Seferidi, Antonio Bernabe-Ortiz, Lindsey Pawlowski, Ellis Ballard

Social System Design Lab

El iceberg es una metáfora clásica que se aplica en diversas disciplinas más allá del pensamientosistémico. La metáfora describe una situación en la cual solo se observa la punta del iceberg, es decir solouna pequeña parte de la totalidad que no se puede ver en la superficie (la gran masa de hielo escondidadebajo de la superficie). En el pensamiento sistémico, se usa la metáfora del iceberg para pensar sobre loque está “bajo la superficie” impulsando los eventos que observamos (punta del Iceberg): (1) Patrones decomportamiento a lo largo del tiempo, (2) Estructuras del sistema que dan lugar a estos patrones …


Modelos Mentales, Clarissa Gaona Romero, Katherine Curi-Quinto, Laura Guzmán Abello, Carmen Quinteros-Reyes, Paraskevi Seferidi, Antonio Bernabe-Ortiz, Lindsey Pawlowski, Ellis Ballard Feb 2022

Modelos Mentales, Clarissa Gaona Romero, Katherine Curi-Quinto, Laura Guzmán Abello, Carmen Quinteros-Reyes, Paraskevi Seferidi, Antonio Bernabe-Ortiz, Lindsey Pawlowski, Ellis Ballard

Social System Design Lab

Un principio central de la perspectiva del pensamiento sistémico es que las estructuras del sistema están respaldadas y permanecen por nuestras creencias, formas de pensar, y objetivos subyacentes (Ver Serie de Informes de Métodos 1.08). Por lo tanto, para transformar y rediseñar los sistemas también debemos transformar nuestra mentalidad. El propósito de este breve documento es introducir el concepto de modelos mentales y discutir cómo las herramientas de dinámica de sistemas se pueden usar para identificarlos, negociarlos y transformarlos.


Wooster Magazine: Spring 2022, Caitlin Paynich Stanowick Feb 2022

Wooster Magazine: Spring 2022, Caitlin Paynich Stanowick

Wooster Magazine: 2021-2030

The spring 2022 issue of Wooster magazine recognizes the legacy of Black voices and student activism at The College of Wooster. While founded on principles of equity and inclusion, throughout history reality has not always met these ideals and the work to ensure that every individual thrives on the Wooster campus, free from bias, harassment, and discrimination remains ongoing. This issue of the magazine outlines Black history and some of the student activism that has driven needed change at the College. It also features the stories of some of the many Wooster alumni who have gone on to make powerful …


The Montclarion February 24, 2022, The Montclarion Feb 2022

The Montclarion February 24, 2022, The Montclarion

The Montclarion

Student Newspaper of Montclair State University


Recommendations For Infection Control In Congregate Shelters Following A Natural Disaster, Megan Schultz, Blaine Winters Feb 2022

Recommendations For Infection Control In Congregate Shelters Following A Natural Disaster, Megan Schultz, Blaine Winters

Student Works

Infection control is at the forefront of nurses’ minds, particularly following a natural disaster. Natural disasters often displace people from their homes, requiring them to stay in congregate shelters for a short period of time. The risk of infection is significantly increased in shelters environments. The purpose of this literature review is to determine the appropriate strategies to mitigate the spread of infection in congregate shelters following a natural disaster. Implications for practice are identified.


Cheminformatics Application In The Phytochemical And Biological Study Of Eucalyptus Globulus L. Bark As A Potential Hepatoprotective Drug, Khaled Nematallah, Sahar Elmekkawy, Maha Abdollah, Mohamed Elmazar, Essam Abdel Sattar, Meselhy R. Meselhy Feb 2022

Cheminformatics Application In The Phytochemical And Biological Study Of Eucalyptus Globulus L. Bark As A Potential Hepatoprotective Drug, Khaled Nematallah, Sahar Elmekkawy, Maha Abdollah, Mohamed Elmazar, Essam Abdel Sattar, Meselhy R. Meselhy

Pharmacy

Natural products are considered as a good source of antifibrotic agents, but identifying and isolating bioactive molecule(s) is still challenging. Fortunately, numerous computational techniques have evolved to save time and efforts in this field. The aim of the current study was to utilize several cheminformatics software to study the chemical and biological features of the bark of Eucalyptus globulus cultivated in Egypt. Sirius software, with the aid of online databases, was used to process liquid chromatography–mass spectrometry (LC–MS) chemical profiling and predict precise molecular formulae, chemical classes, and structures. Accordingly, 37 compounds were tentatively identified, including 15 reported here for …


Trophic Relationships In Larval California Newts (Taricha Torosa), Michael P. Marchetti, Kirsti Dunkel, Charlotte Moxley Feb 2022

Trophic Relationships In Larval California Newts (Taricha Torosa), Michael P. Marchetti, Kirsti Dunkel, Charlotte Moxley

Western North American Naturalist

The larval stage of the California newt (Taricha torosa) has been little studied despite the presence and abundance of the species throughout much of California. During the 2017–2018 time period, the diet and life history characteristics of this cohort of stream-dwelling newt larvae were examined, using gut contents and stable isotopes, in order to better understand the ecological niche and trophic relationships of the life stage. Our results suggest that the newt larvae consume Chironomidae as a major part of their diet and that this reliance decreases as the larvae age. Newt larvae also feed more widely and …


Neighborhood Deprivation And Risk Of Mortality Among Men With Prostate Cancer: Findings From A Long-Term Follow-Up Study, Madhav Kc, Evrim Oral, Ariane L. Rung, Edward J. Trapido, Laura S. Rozek, Elizabeth T.H. Fontham, Jeannette T. Bensen, Laura Farnan, Susan E. Steck, Lixin Song, James L. Mohler, Edward S. Peters Feb 2022

Neighborhood Deprivation And Risk Of Mortality Among Men With Prostate Cancer: Findings From A Long-Term Follow-Up Study, Madhav Kc, Evrim Oral, Ariane L. Rung, Edward J. Trapido, Laura S. Rozek, Elizabeth T.H. Fontham, Jeannette T. Bensen, Laura Farnan, Susan E. Steck, Lixin Song, James L. Mohler, Edward S. Peters

School of Public Health Faculty Publications

Background: The overall survival rate of prostate cancer (PCa) has improved over the past decades. However, huge socioeconomic and racial disparities in overall and prostate cancer-specific mortality exist. The neighborhood-level factors including socioeconomic disadvantage and lack of access to care may contribute to disparities in cancer mortality. This study examines the impact of neighborhood deprivation on mortality among PCa survivors. Methods: North Carolina–Louisiana Prostate Cancer Project (PCaP) data were used. A total of 2113 men, 1046 AA and 1067 EA, with PCa were included in the analysis. Neighborhood deprivation was measured by the Area Deprivation Index (ADI) at the census …


Viral Ejection Proteins: Mosaically Conserved, Conformational Gymnasts, Nicholas A. Swanson, Chun-Feng Hou, Gino Cingolani Feb 2022

Viral Ejection Proteins: Mosaically Conserved, Conformational Gymnasts, Nicholas A. Swanson, Chun-Feng Hou, Gino Cingolani

Department of Biochemistry and Molecular Biology Faculty Papers

Bacterial viruses (or bacteriophages) have developed formidable ways to deliver their genetic information inside bacteria, overcoming the complexity of the bacterial-cell envelope. In short-tailed phages of the Podoviridae superfamily, genome ejection is mediated by a set of mysterious internal virion proteins, also called ejection or pilot proteins, which are required for infectivity. The ejection proteins are challenging to study due to their plastic structures and transient assembly and have remained less characterized than classical components such as the phage coat protein or terminase subunit. However, a spate of recent cryo-EM structures has elucidated key features underscoring these proteins’ assembly and …


Neighborhood Deprivation And Risk Of Mortality Among Men With Prostate Cancer: Findings From A Long-Term Follow-Up Study, Madhav K.C., Ariane L. Rung, Edward J. Trapido, Laura S. Rozek, Elizabeth T.H. Fontham, Jeannette T. Bensen, Laura Farnan, Susan E. Steck Phd, Mph, Rd, Lixin Song, James L. Mohler, Edward S. Peters Feb 2022

Neighborhood Deprivation And Risk Of Mortality Among Men With Prostate Cancer: Findings From A Long-Term Follow-Up Study, Madhav K.C., Ariane L. Rung, Edward J. Trapido, Laura S. Rozek, Elizabeth T.H. Fontham, Jeannette T. Bensen, Laura Farnan, Susan E. Steck Phd, Mph, Rd, Lixin Song, James L. Mohler, Edward S. Peters

Faculty Publications

Background The overall survival rate of prostate cancer (PCa) has improved over the past decades. However, huge socioeconomic and racial disparities in overall and prostate cancer-specific mortality exist. The neighborhood-level factors including socioeconomic disadvantage and lack of access to care may contribute to disparities in cancer mortality. This study examines the impact of neighborhood deprivation on mortality among PCa survivors. Methods North Carolina–Louisiana Prostate Cancer Project (PCaP) data were used. A total of 2113 men, 1046 AA and 1067 EA, with PCa were included in the analysis. Neighborhood deprivation was measured by the Area Deprivation Index (ADI) at the census …


A Descriptive Mixed-Methods Study Examining Resilience And Transitioning To Adulthood Among Emerging Adults With Disabilities, Jennifer Emilie Mannino Feb 2022

A Descriptive Mixed-Methods Study Examining Resilience And Transitioning To Adulthood Among Emerging Adults With Disabilities, Jennifer Emilie Mannino

Dissertations

Transitioning to adulthood is not without challenges. The move away from family influence towards independence and self-determination is filled with uncertainty. Increased challenges and vulnerabilities in transitioning are evident among emerging adults with disabilities because they face additional challenges related to their disability over and above what others of this developmental stage experience.


Increased Drp1 Promotes Autophagy And Escc Progression By Mtdna Stress Mediated Cgas-Sting Pathway., Yujia Li, Hui Chen, Qi Yang, Lixin Wan, Jing Zhao, Yuanyuan Wu, Jiaxin Wang, Yating Yang, Menglan Niu, Hongliang Liu, Junqi Liu, Hushan Yang, Shaogui Wan, Yanming Wang, Dengke Bao Feb 2022

Increased Drp1 Promotes Autophagy And Escc Progression By Mtdna Stress Mediated Cgas-Sting Pathway., Yujia Li, Hui Chen, Qi Yang, Lixin Wan, Jing Zhao, Yuanyuan Wu, Jiaxin Wang, Yating Yang, Menglan Niu, Hongliang Liu, Junqi Liu, Hushan Yang, Shaogui Wan, Yanming Wang, Dengke Bao

Department of Medical Oncology Faculty Papers

Background: Mitochondrial dynamics homeostasis is important for cell metabolism, growth, proliferation, and immune responses. The critical GTPase for mitochondrial fission, Drp1 is frequently upregulated in many cancers and is closely implicated in tumorigenesis. However, the mechanism underling Drp1 to influence tumor progression is largely unknown, especially in esophageal squamous cell carcinoma (ESCC).

Methods: Immunohistochemistry was used to examine Drp1 and LC3B expression in tissues of ESCC patients. Autophagic vesicles were investigated by transmission electron microscopy. Fluorescent LC3B puncta and mitochondrial nucleoid were observed by fluorescent and confocal microscopy. Mitochondrial function was evaluated by mitochondrial membrane potential, ROS and ATP levels. …


Labor Induction With Oxytocin In Pregnant Rats Is Not Associated With Oxidative Stress In The Fetal Brain, Tusar Giri, Jia Jiang, Zhiqiang Xu, Ronald Mccarthy, Carmen M Halabi, Eric Tycksen, Alison G Cahill, Sarah K England, Arvind Palanisamy Feb 2022

Labor Induction With Oxytocin In Pregnant Rats Is Not Associated With Oxidative Stress In The Fetal Brain, Tusar Giri, Jia Jiang, Zhiqiang Xu, Ronald Mccarthy, Carmen M Halabi, Eric Tycksen, Alison G Cahill, Sarah K England, Arvind Palanisamy

Open Access Publications

Despite the widespread use of oxytocin for induction of labor, mechanistic insights into fetal/neonatal wellbeing are lacking because of the absence of an animal model that recapitulates modern obstetric practice. Here, we create and validate a hi-fidelity pregnant rat model that mirrors labor induction with oxytocin in laboring women. The model consists of an implantable preprogrammed microprocessor-controlled infusion pump that delivers a gradually escalating dose of intravenous oxytocin to induce birth at term gestation. We validated the model with molecular biological experiments on the uterine myometrium and telemetry-supported assessment of changes in intrauterine pressure. Finally, we applied this model to …


The Bidirectional Relationship Between Posttraumatic Stress Symptoms And Social Support In A 9/11-Exposed Cohort: A Longitudinal Cross-Lagged Analysis, Sze Yan Liu, Jiehui Li, Lydia F. Leon, Ralf Schwarzer, James E. Cone Feb 2022

The Bidirectional Relationship Between Posttraumatic Stress Symptoms And Social Support In A 9/11-Exposed Cohort: A Longitudinal Cross-Lagged Analysis, Sze Yan Liu, Jiehui Li, Lydia F. Leon, Ralf Schwarzer, James E. Cone

Department of Public Health Scholarship and Creative Works

Research on the longitudinal relationship between posttraumatic stress disorder (PTSD) and social support among survivors of large-scale trauma is limited. This study assessed bidirectional relationships between PTSD and perceived social support in a large sample of the 9/11-exposed cohort over a 14-year follow-up. We used data from 23,165 World Trade Center Health Registry (WTCHR) enrollees who were exposed to the 9/11 attacks and participated in the first four WTCHR surveys (Wave 1 (2003–2004) to Wave 4 (2015–2016)). PTSD symptoms were measured using the 17-item PTSD Checklist. Perceived social support was measured using the five-item version of the Modified Social Support …


Covid-19 Pandemic Analysis By The Volterra Integral Equation Models: A Preliminary Study Of Brazil, Italy, And South Africa, Yajni Warnapala, Emma Dehetre, Kate Gilbert Feb 2022

Covid-19 Pandemic Analysis By The Volterra Integral Equation Models: A Preliminary Study Of Brazil, Italy, And South Africa, Yajni Warnapala, Emma Dehetre, Kate Gilbert

Arts & Sciences Faculty Publications

The COVID-19 pandemic has affected many people throughout the world. The objective of this research project was to find numerical solutions through the Gaussian Quadrature Method for the Volterra Integral Equation Model. The non-homogenous Volterra Integral Equation of the second kind is used to capture a broader range of disease distributions. Volterra Integral equation models are used in the context of applied mathematics, public health, and evolutionary biology. The mathematical models of this integral equation gave valid convergence results for the COVID-19 data for 3 countries Italy, South Africa and Brazil. The modeling of these countries was done using the …


Addressing The Disparities In Dementia Risk, Early Detection And Care In Latino Populations: Highlights From The Second Latinos & Alzheimer's Symposium, Yakeel T. Quiroz, Michele Solis, María P. Aranda, Alicia I. Arbaje, Mirna Arroyo-Miranda, Laura Y. Cabrera, Minerva Maria Carrasquillo, Maria M. Corrada, Gladys E. Maestre, Rosa V. Pirela Feb 2022

Addressing The Disparities In Dementia Risk, Early Detection And Care In Latino Populations: Highlights From The Second Latinos & Alzheimer's Symposium, Yakeel T. Quiroz, Michele Solis, María P. Aranda, Alicia I. Arbaje, Mirna Arroyo-Miranda, Laura Y. Cabrera, Minerva Maria Carrasquillo, Maria M. Corrada, Gladys E. Maestre, Rosa V. Pirela

School of Medicine Publications

The Alzheimer's Association hosted the second Latinos & Alzheimer's Symposium in May 2021. Due to the COVID-19 pandemic, the meeting was held online over 2 days, with virtual presentations, discussions, mentoring sessions, and posters. The Latino population in the United States is projected to have the steepest increase in Alzheimer's disease (AD) in the next 40 years, compared to other ethnic groups. Latinos have increased risk for AD and other dementias, limited access to quality care, and are severely underrepresented in AD and dementia research and clinical trials. The symposium highlighted developments in AD research with Latino populations, including advances …


Improving Prediction Of Amyloid Deposition In Mild Cognitive Impairment With A Timed Motor Task, Sydney Y. Schaefer, Kevin Duff, Andrew Hooyman, John M. Hoffman Feb 2022

Improving Prediction Of Amyloid Deposition In Mild Cognitive Impairment With A Timed Motor Task, Sydney Y. Schaefer, Kevin Duff, Andrew Hooyman, John M. Hoffman

Physical Therapy Faculty Articles and Research

Cortical amyloid deposition is one of the hallmark biomarkers of Alzheimer’s disease (AD). However, given how cost- and time-intensive amyloid imaging can be, there is a continued need for a low-cost, non-invasive, and accessible enrichment strategy to pre-screen individuals for their likelihood of amyloid prior to imaging. Previous work supports the use of coordinated limb movement as a potential screening tool, even after controlling for cognitive and daily function. Thirty-six patients diagnosed with amnestic mild cognitive impairment over the age of 65 underwent 18F-Flutemetamol amyloid-positron emission tomography Cortical amyloid deposition is one of the hallmark biomarkers of Alzheimer’s disease (AD). …


Pollen-Based Maps Of Past Regional Vegetation Cover In Europe Over Twelve Millennia - Evaluation And Potential, Esther Githumbi, Behnaz Pirzamanbein, Johan Lindström, Anneli Poska, Ralph Fyfe, Florence Mazier, Anne Brigitte Nielsen, Shinya Sugita, Anna Kari Trondman, Jessie Woodbridge, Marie José Gaillard Feb 2022

Pollen-Based Maps Of Past Regional Vegetation Cover In Europe Over Twelve Millennia - Evaluation And Potential, Esther Githumbi, Behnaz Pirzamanbein, Johan Lindström, Anneli Poska, Ralph Fyfe, Florence Mazier, Anne Brigitte Nielsen, Shinya Sugita, Anna Kari Trondman, Jessie Woodbridge, Marie José Gaillard

School of Geography, Earth and Environmental Sciences

No abstract provided.


Synthesis And Structure-Activity Relationship Of Thioacetamide-Triazoles Against Escherichia Coli, Suresh Dharuman, Miranda J Wallace, Stephanie M Reeve, Jürgen B Bulitta, Richard E Lee Feb 2022

Synthesis And Structure-Activity Relationship Of Thioacetamide-Triazoles Against Escherichia Coli, Suresh Dharuman, Miranda J Wallace, Stephanie M Reeve, Jürgen B Bulitta, Richard E Lee

Open Access Publications

Infections due to Gram-negative bacteria are increasingly dangerous due to the spread of multi-drug resistant strains, emphasizing the urgent need for new antibiotics with alternative modes of action. We have previously identified a novel class of antibacterial agents, thioacetamide-triazoles, using an antifolate targeted screen and determined their mode of action which is dependent on activation by cysteine synthase A. Herein, we report a detailed examination of the anti-


Kenyon Collegian - February 24, 2022 Feb 2022

Kenyon Collegian - February 24, 2022

The Kenyon Collegian

No abstract provided.