Digital Commons Network^™

Expression Of Dementia Biomarkers In Appalachian And Non-Appalachian Elvo Patients During Thrombectomy, Neha Anil, Christopher J. Mclouth, Hunter S. Hazelwood, Elise Dahlke, Jacqueline A. Frank, Nathan Millson, Mais Al-Kawaz, Jordan P. Harp, Will Cranford, Shivani Pahwa, David Dornbos Iii, Justin F. Fraser, Keith R. Pennypacker

University Faculty Publications and Creative Works

Vascular Cognitive Impairment and Dementia (VCID) affects 25-30% of stroke patients and includes cognitive impairments caused by vascular injury, such as post-stroke dementia. Rehabilitation has the potential to improve the quality of life for patients at risk of developing dementia. However, there is currently no reliable method to identify those at risk of dementia after a stroke. Several biomarkers, including ADRD (Alzheimer’s disease and related dementias) biomarkers (Ab, tau, NfL, and GFAP) and angiogenic factors (VEGF, Flt-1, Tie-2, PIGF, and FGF) have been associated with the development of dementia. Populations in Appalachia experience a higher incidence of stroke and related …

The Web Of Tpd Reform: A Reflective Tool For Analyzing And Improving Teaching Professional Development Programs For Teaching Assistants, Adam J. Chouinard, Diyala S. Shihadih, Star W. Lee, Stephanie J. Gutzler, Kaleb K. Heinrich, Mitra Asgari, Erin Shortlidge

Biology Faculty Publications and Presentations

Teaching assistants (TAs) play a pivotal role in the teaching mission of higher education, but too often they are asked to do this important job without adequate teaching professional development (TPD). By receiving training in inclusive and evidence-based teaching practices, TAs can in turn help disseminate effective teaching methods for the benefit of students throughout the nation; as future faculty, TPD also better prepares TAs for their careers, helps solve longstanding problems of inclusion and retention in STEM, and reforms disciplinary educational norms through cultural evolution. Thanks to prior research and advocacy efforts, there is a growing awareness that STEM …

Postmortem Vitreous Humor As An Alternative Matrix To Peripheral Blood For Benzodiazepine Detection, Sara Bussey

Honors Theses

Benzodiazepines are commonly prescribed secondary drugs of abuse that cause Central Nervous System depression through the neurotransmitter gamma aminobutyric acid. While not commonly fatal on their own, benzodiazepines have a minor risk for physical dependence and abuse. They also can have cumulative effects with other medications that can lead to overdose situations; thus, they are considered secondary drugs of abuse. While peripheral blood is considered the standard for xenobiotic detection in postmortem forensic toxicology, it is important to consider the validity of alternative matrices that could be analyzed in the event that blood was not available due to circumstances like …

Association Between Adherence Barriers, Self-Reported Adherence, And Psychiatric Symptoms Among Adults With Bipolar Disorder, Martha Sajatovic, Jennifer B. Levin, Clara Adeniyi, Jessica Black, Celeste Weise, Nicole Fiorelli, Erika Kelley

Faculty Scholarship

Aims: While suboptimal medication adherence is a widely recognized problem for people with bipolar disorder (BD), it is less clear how individual characteristics are associated with varying levels of adherence and how specific adherence barriers impact behaviors. This interim analysis from an ongoing randomized controlled trial (RCT) examined associations between patient-reported adherence, adherence barriers, and mood symptoms among poorly adherent individuals with BD. Methods: RCT participants were adults age ≥ 18 years old with BD Type 1 or 2, difficulties with medication adherence, and actively symptomatic as measured by Brief Psychiatric Rating Scale (BPRS) score ≥ 36, Young Mania Rating …

Cardiac Sr-Mitochondria Contacts-Impact On Cardiac Physiology And Mitochondrial Fitness, Celia Fernandez-Sanz, Shey-Shing Sheu, Sergio De La Fuente

Center for Translational Medicine Faculty Papers

In adult cardiomyocytes, within the Mitochondrial Associated Membranes (MAMs), the sarcoplasmic reticulum (SR) and mitochondria juxtapose each other, forming a unique and highly repetitive functional structure throughout the cells. These SR-mitochondria contact sites have emerged as critical structures that regulate various physiological processes, including lipid exchange, calcium (Ca²⁺) communication, control of excitation-contraction bioenergetics coupling, and reactive oxygen species (ROS) production. Over the years, several scientific studies have reported the accumulation of diverse proteins within these SR-mitochondria close contacts. Some proteins strategically accumulate in these areas to enhance their function, such as the mitochondrial Ca²⁺ uniporter, while others …

Exploring Counselor Perspectives On The Role Of Ecotherapy In Mental Health Treatment: A Qualitative Study, Kimberly Seid

Walden Dissertations and Doctoral Studies

This grounded qualitative study explored the common themes of ecotherapy in practice. The research problem was the limited understanding of how counselors implement ecotherapy in clinical practice, hindering the field’s ability to fully integrate nature-based approaches into mental health treatment. The purpose of this grounded theory study was to explore counselor perspectives on ecotherapy using the biophilia hypothesis and Swarbrick’s wellness model. The research questions focused on how licensed mental health counselors understood, implemented, and evaluated the impact of ecotherapy. Qualitative data were collected through an online survey with open-ended questions from 15 licensed counselors across the United States who …

Hydration Strategies In Ultra-Endurance Running: A Narrative Review Of Programmed Versus Thirst-Driven Approaches, Shawn C. Wierick, Rosie I. Perez, Xiujing Zhao, Brendon P. Mcdermott

Health, Human Performance and Recreation Faculty Publications and Presentations

Background/Objectives: Ultra-endurance running (UER) presents unique hydration challenges due to prolonged duration, variable terrain, environmental extremes, and gastrointestinal limitations. Athletes often use either programmed fluid intake (PFI), which prescribes fluid volumes based on estimated sweat rate, or thirst-driven fluid intake (TDFI), which relies on internal cues. This review examines the effectiveness and limitations of each strategy in the context of UER performance and safety. Methods: A narrative review was conducted using a targeted selection of peer-reviewed studies. Both laboratory- and field-based research were included to evaluate the physiological rationale, practical feasibility, and outcomes associated with PFI and TDFI. A total …

The Impact Of Microaggression Exposure On Emotional Reactivity And Distress Following An Emotionally Provocative Movie Scene, Gwendolyn Jefferson

Walden Dissertations and Doctoral Studies

This quantitative study explored how past experiences with racial microaggressions affect emotional reactions to racially charged media and whether factors like age and gender influence that response. Using Minority Stress Theory as a guide, 183 African American adults completed the Racial and Ethnic Microaggressions Scale and the State-Trait Anxiety Inventory before and after watching a racially provocative film clip. The first analysis found no direct link between microaggression exposure and emotional change. However, further testing with analysis of variance showed that people with higher exposure reported much stronger emotional distress than those with lower exposure, F(1,180) = 38.12, p < .001, η² = .175. When demographic factors were added in a hierarchical regression, the model became significant, F(7,175) = 2.06, p = .036, R² = .076, showing that age (β = .086, p = .009) and gender (β = 1.505, p = .039) influenced emotional responses. Thus, older African American women showed the strongest distress, suggesting that the combined effects of race, gender, and age increase vulnerability to racial stress. These findings support the idea that racial trauma is complex and shaped by overlapping social identities. The study highlights the need for culturally sensitive mental health support, inclusive media portrayals, and greater awareness of generational and caregiving stress among African American women. By showing how overlapping identities shape emotional well-being, this research advances social change through empathy, reduced stigma, and institutional accountability, encouraging equity-driven practices that foster racial healing, fairness, and psychological resilience across communities.

Infection After Cd19 Chimeric Antigen Receptor T-Cell Therapy For Large B-Cell Lymphoma: Real-World Analysis From Cibmtr, Kitsada Wudhikarn, Megan M Herr, Min Chen, Michael J Martens, John H Baird, Lohith Gowda, Hemalatha G Rangarajan, Muhammad Bilal Abid, Mohamed A Kharfan-Dabaja, Kirsten M Williams, Siddhartha Ganguly, Jo-Anne H Young, Akshay Sharma, Giancarlo Fatobene, Tania Jain, Christopher G Kanakry, Dipenkumar Modi, Natalie S Grover, Baheyeldin Salem, Marjorie Vieira Batista, Paschalis Vergidis, Dwight E Yin, Amer M Beitinjaneh, Amar H Kelkar, Taiga Nishihori, Jennifer Holter Chakrabarty, Usama Gergis, Melody Smith, Zeinab El Boghdadly, Christopher E Dandoy, Hemant S Murthy, Anna R Huppler, Miguel-Angel Perales, Roy F Chemaly, Joshua A Hill, Marcie Riches, Jeffery J Auletta

Faculty, Staff and Students Publications

Infection is increasingly recognized as a significant cause of morbidity and mortality in patients with relapsed/refractory (R/R) large B-cell lymphoma (LBCL) receiving CD19 chimeric antigen receptor (CAR) T-cell therapy. The current study analyzed the natural history, risk factors, and outcomes of infection in 3350 patients with R/R LBCL receiving commercial CD19 CAR T-cell therapy (n = 2804 axicabtagene ciloleucel [axi-cel], n = 546 tisagenlecleucel) from December 2017 to June 2022. Infection developed in 834 patients (24.9%) within 100 days after infusion, resulting in an infection density of 0.43 per 100 patient days and a 100-day cumulative incidence of 22%. Bacterial, …

Geneseo Authors Celebration 2025, Milne Library

Geneseo Authors Celebration

Milne Library began a tradition of celebrating faculty authorship in 2009 with a series of workshops and a celebration in collaboration with the Teaching and Learning Center. Over the years it has evolved to more accurately reflect on the variety of academic and creative work done here at Geneseo. The annual Geneseo Authors Celebration is an opportunity for the Library and the campus to celebrate the faculty and truly acknowledge the time and effort that faculty have invested into creating exceptional works that contribute to the scholarly discussions taking place in their disciplines.

Books authored or edited by Geneseo faculty …

The Lived Experiences Of Imposter Syndrome Among Women Of Color Professors In Higher Education, Adrianna Marie Hooker

Walden Dissertations and Doctoral Studies

This qualitative phenomenological study explored the unique challenges faced by women of color professors in higher education, who often experience imposter syndrome due to systemic barriers and underrepresentation. The purpose of this study was to gain an in-depth understanding of how these professors experienced and made meaning of imposter syndrome in academic settings. The central research question examined the meaning of imposter syndrome among women of color professors in higher education. This study was grounded in intersectionality and self-determination theory, which provided frameworks for understanding how multiple identities influenced feelings of inadequacy and professional identity. Participants included 12 women of …

Epigenetic Landscape In Lysosomal Storage Disorders: Mechanisms And Modulation, Andrés Felipe Leal, Harry Pachajoa, Shunji Tomatsu

Department of Pediatrics Faculty Papers

Lysosomal storage disorders (LSDs) are rare substrate-accumulating diseases primarily characterized by mutations in genes encoding proteins involved in lysosomal function, most of which have enzymatic activity. Resulting lysosomal dysfunction leads to the overaccumulation of non- or partially degraded substrates. While it is true that enzyme deficiency is the primary cause of LSDs, the epigenetic alterations in DNA methylation, miRNA expression, and histone modifications appear to be critical mechanisms involved in the pathogenesis of LSDs. As epigenetic marks are, in most cases, reversible, their study becomes vital to developing strategies aimed at reversing epigenome alterations. Although classical therapeutic alternatives aim to …

Preclinical Efficacy Of Tasquinimod-Based Combinations In Advanced Myeloproliferative Neoplasms In Blastic Phase, Warren Fiskus, Lucia Masarova, Christopher P Mill, Christine E Birdwell, Kaberi Das, Hanxi Hou, John A Davis, Antrix Jain, Anna Malovannaya, Taghi Manshouri, Andrew Dunbar, Surbhi Sharma, Tapan M Kadia, Courtney D Dinardo, Prithviraj Bose, Naveen Pemmaraju, Sanam Loghavi, Xiaoping Su, Raajit K Rampal, Marie Törngren, Kapil N Bhalla

Faculty, Staff and Students Publications

The alarmins, S100A8 (A8) and S100A9 (A9), are low molecular weight proteins belonging to the S100 protein family. A8 and A9 are secreted into the extracellular space and plasma, in which they interact with Toll-like receptor 4, receptor for advanced glycation end products, and CD33. In these studies, we determined the preclinical efficacy of tasquinimod (TQ) against advanced myeloproliferative neoplasm (MPN) cell lines and patient-derived (PD) CD34+ blastic phase (BP; >5% blasts in the peripheral blood) MPN cells. TQ induced loss of viability in cell lines and PD MPN-BP cells, but not in normal CD34+ progenitor cells. In TQ-treated PD …

Real-World Outcomes Of Infections Following Tisagenlecleucel In Patients With B-Cell All: A Cibmtr Analysis, Hemalatha G Rangarajan, Prakash Satwani, Megan M Herr, Min Chen, Michael J Martens, Kitsada Wudhikarn, Samuel John, Vanessa A Fabrizio, Emily M Hsieh, Amar H Kelkar, Erin Doherty, David I Marks, Olle Ringden, Brian Friend, Matthew S Kelly, Nosha Farhadfar, Tim Prestidge, Nasheed M Hossain, Hongtao Liu, Shahrukh Hashmi, Dipenkumar Modi, Lena E Winestone, Zeinab El Boghdadly, Hemant S Murthy, Miguel-Angel Perales, Roy F Chemaly, Christopher E Dandoy, Joshua A Hill, Anna Huppler, Marcie Riches, Jeffery J Auletta

Faculty, Staff and Students Publications

Tisagenlecleucel (tisa-cel) is a CD19-directed chimeric antigen receptor T-cell therapy for relapsed/refractory precursor B-cell acute lymphoblastic leukemia (R/R B-ALL). We report infectious complications for 100 days (D100) following tisa-cel therapy in 471 pediatric and young adults (median age 13.8 years) with R/R B-ALL reported from September 2017 to June 2022. By D100, 137 (29%) patients had an infectious event, with an infection density of 0.542 per 100 person-days at risk. D100 cumulative incidences of bacterial, viral, and fungal infections were 14.1%, 11.6%, and 1.3%, corresponding to infection density scores of 0.296, 0.213, and 0.033 per 100 person-days at risk, respectively. …

Hepatic Ischemia-Reperfusion Injury: Underlying Mechanisms And Concepts In Liver Surgery And Liver Transplantation, Jie Zhao, Lidan Hou, Kenneth J Dery, Xiaoyi Yuan, Kang Ho Kim, Jerzy W Kupiec-Weglinski, David R Hall, Caitlin J Thornley, Mark J Hobeika, Holger K Eltzschig, Cynthia Ju

Faculty, Staff and Student Publications

Hepatic ischemia-reperfusion injury (H-IRI) is a critical complication in liver surgery and liver transplantation, contributing to graft dysfunction and poor clinical outcomes. When hepatocyte protective mechanisms are insufficient to counteract energy depletion and oxidative stress during ischemia, cell death occurs. Tissue damage during H-IRI leads to the release of damage-associated molecular patterns (DAMPs), which recruit and activate immune cells such as neutrophils and monocytes, orchestrating the initiation, progression, and eventual resolution of sterile inflammation. Extended criteria donor (ECD) livers, particularly steatotic ones, are more vulnerable to H-IRI, leading to poorer outcomes and limiting expansion of the donor pool. However, the …

Reprogramming Tumor Microenvironment Via Systemic Delivery Of Tlr3 Agonist And Manganese Nanoparticle, Young Seok Cho, Xingwu Zhou, Xiaoqi Sun, Ziye Wan, Julia Crowther, Mariko Takahashi, Swetha Kodamasimham, Qi Wu, May Thazin Phoo, Youngseo Na, Kai Han, Zaiye Li, Anna Schwendeman, Steven P Schwendeman, Yu Leo Lei, James J Moon

Faculty, Staff and Student Publications

Toll-like receptor (TLR) agonists, as potent immunostimulatory adjuvants, play a critical role in linking the innate and adaptive immune responses. However, their antitumor effects as cancer immunotherapeutic agents have been limited. Here, we report our finding that manganese ion (Mn2+) potentiates various TLR agonists, leading to robust activation of the TLR pathway and the stimulator of interferon genes (STING) pathway among innate immune cells. In particular, we have observed robust antitumor efficacy after intratumoral administration of a TLR3 agonist and Mn2+. To achieve systemic codelivery of TLR3 agonist and Mn2+, we have developed a low-molecular-weight poly(inosinic:cytidylic acid)-Mn2+ coordination lipid nanoparticle …

Cerebral Malaria And Multi-Organ Dysfunction Caused By Plasmodium Vivax In An Adult: A Case From Oman With A Literature Review, Saba M. Al Kindi, Shabnam Chhetri, Zahrah Z. Al Aamri, Suchata D. Dhuri, Zakariya Y. Al Balushi, Faryal Khamis

Sultan Qaboos University Medical Journal

Cerebral malaria is a life-threatening complication most commonly associated with Plasmodium falciparum. To the best of the authors’ knowledge, this is the first documented case in Oman of a previously healthy 38-year-old Pakistani male who presented to the Emergency Department of a tertiary care hospital in 2025 with cerebral malaria and multi-organ dysfunction syndrome (MODS) caused by Plasmodium vivax, confirmed by peripheral blood smear and polymerase chain reaction (PCR). The patient was treated with intravenous (IV) artesunate and supportive intensive care, resulting in full neurological recovery. This case highlights the importance of considering P. vivax as a potential …

Targeted Injection Therapies For Temporomandibular Joint Disorders: A Comparative Review Of Hyaluronic Acid And Botox Techniques, Timothy Alexander, Marissa Siegel, Noah Schnoor, Elizabeth A. Starns

Journal of Sports Medicine and Allied Health Sciences: Official Journal of the Ohio Athletic Trainers Association

Purpose: This study aimed to evaluate the effectiveness of different injection therapies for temporomandibular joint disorders (TMD) and answer the research question: how do botulinum toxin (onabotulinumtoxinA, Botox) and hyaluronic acid (HA) injections affect symptoms of temporomandibular joint disorder (TMD)? Methods: An electronic search of three databases was performed using the search terms “Treatment of TMD or TMJ” and one of the following: 1) “Hyaluronic Acid Injection” or 2) “Intramuscular Botox Injection”. Based on studies done with human patients, the effects of both hyaluronic acid and Botox injections as treatments for TMD were observed and analyzed. Inclusion criteria were: full …

Instructors’ Needs For Teaching And Mentoring Undergraduate Students In The Water Sciences, Silvia-Jessica Mostacedo-Marasovic, Kristin Raub, Deanna Mccay, Cory Forbes

Journal of Contemporary Water Research and Education

Undergraduate education in water resources is crucial, involving faculty from diverse disciplines and providing meaningful learning and mentoring experiences. In 2022, the Consortium of Universities for the Advancement of Hydrologic Science, Inc. (CUAHSI) launched a national survey and organized a virtual collaborative session with respondents to better understand: 1) What are the primary needs faced by faculty members who teach and mentor water science to undergraduate students? and 2) How can academic institutions and external organizations effectively support faculty members in meeting the needs associated with teaching and mentoring water science to undergraduate students? We collected data from N = …

Developmental Effects On Zebrafish Embryos Exposed To Alcohol, Tamya Mchaney

Science University Research Symposium (SURS)

Zebrafish are a good organism model due to their similarities with human biology. The transparency of their embryos allows for an easier view to see the developmental stages of the embryos, and easily and accurately note any mutations or defects in any of the embryos. In addition, they make excellent candidates to track potential effects that mirror human embryos with ethanol and alcohol will have on their developmental stages. The aim of this study was to measure the genetic size developmental differences of the embryo’s lens, eyes, and heart that are given 1% alcohol and 2% alcohol. This study’s experimental …

The Effect Of Leaf Composition And Structure On Decomposition Rates In Primula Sp. And Allium Schoenoparsum, Tatum P. Fortney, Kidist Aklile, Matty Mackay, Solomon Kap

Science University Research Symposium (SURS)

Decomposition is the process by which dead organic matter is broken down by bacteria and fungi. Leaves are a prominent form of organic matter that decomposes and enriches soil by returning nutrients. In this experiment, chive and primrose leaves were investigated. Chive leaves are thinner and softer, while primrose leaves are thicker and more dense, supporting our hypothesis that Chive leaf litter will decompose faster than primrose leaf litter because chives have a lower lignin content and are structurally narrower, making them easier to decompose. For this experiment, we placed around 4 grams of both species into a series of …

Patient Safety In Ambulatory Hysteroscopy, Myko Lanier

Walden Dissertations and Doctoral Studies

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Epithelial Collective Response To Immune Cells, Matrix Proteins, And Mechanical Cues, Hannah Maria Zmuda

McKelvey School of Engineering Graduate Student Theses & Dissertations

Epithelial cells form complex and dynamic tissue structures within the human body. During these processes, cells must come in contact with a variety of dissimilar cell types, extracellular matrix (ECM) proteins, and mechanical changes not aligned with homeostasis. In this thesis, we explore how changes to the surrounding environment can impact mechanoresponse of epithelial cells. We developed an in vitro system by using elastically tunable polyacrylamide substrates with collagen coating to understand how mechanics can affect collective cell migration. In the first aim, we added macrophages chemically polarized as M0, M1, or M2-like macrophages co-cultured with epithelial cells. We found …

Assessing The Role Of Social Media As A Complementary Source In Pharmacovigilance: Insights From Faers, X (Formerly Twitter), And Askapatient Data Across Multiple Drug Classes, Nwanneka Okere

Dissertations

Background: Adverse drug reactions (ADRs) pose significant public health challenges yet remain substantially underreported in traditional pharmacovigilance systems. Social media platforms and patient-reported outcome forums have emerged as potential complementary sources for capturing real-time patient experiences with medications, but their integration with established surveillance systems remains underexplored.

Purpose: This study examined ADR reporting patterns across FDA Adverse Event Reporting System (FAERS), X (formerly Twitter), and Askapatient to evaluate whether patient-generated digital data can complement traditional pharmacovigilance systems for enhanced drug safety monitoring.

Methods: An explanatory sequential mixed-methods design analyzed 107,753 reports representing 289,740 individual ADR occurrences for …

The Effect Of Leaf Composition And Structure On Decomposition Rates In Primula Sp. And Allium Schoenoparsum, Tatum P. Fortney, Darlene Panvini, Kidist Aklile, Matty Mackay, Solomon Kap

Science University Research Symposium (SURS)

Decomposition is the process by which dead organic matter is broken down by bacteria and fungi. Leaves are a prominent form of organic matter that decomposes and enriches soil by returning nutrients. In this experiment, chive and primrose leaves were investigated. Chive leaves are thinner and softer, while primrose leaves are thicker and more dense, supporting our hypothesis that Chive leaf litter will decompose faster than primrose leaf litter because chives have a lower lignin content and are structurally narrower, making them easier to decompose. For this experiment, we placed around 4 grams of both species into a series of …

Evaluating The Effects Of Water Quality And Anthropogenic Disturbance On Salamander Species Diversity, Abundance And Health In Warner Parks, Tatum P. Fortney, Chase Kinsey

Science University Research Symposium (SURS)

Salamanders utilize cutaneous respiration, making them vulnerable to pollution, shifts in water chemistry, and habitat degradation. Increased anthropogenic habitat use may be a detriment to local salamander populations and pollution increases with land use. Understanding how water quality influences salamander abundance, diversity and physiological condition is crucial for amphibian conservation and for assessing freshwater ecosystem health, as they serve as a key bioindicator species. The objective of this study was to examine how variation in water quality parameters influences salamander species abundance, diversity and locomotor performance across stream sites within Warner Parks in Nashville, Tennessee. Field sampling was conducted weekly …

Pd-1 Blockade Induced Bone Loss Occurs In A T-Cell Dependent Manner And May Be Mediated By Ifnγ-Driven Osteoclast Activation, Elena Amonette, Paige M. Hill

Science University Research Symposium (SURS)

PD-1 Blockade Induced Bone Loss Occurs in a T-Cell Dependent Manner and May Be Mediated by IFNγ-Driven Osteoclast Activation

^†Elena Amonette¹, ^†Paige Hill¹, Gwenyth J. Joseph², Rachelle W. Johnson^2,3

¹Belmont University, Nashville, TN; ²Vanderbilt University, Nashville, TN; ³Vanderbilt University Medical Center, Nashville, TN

^†These authors contributed equally to this work

Immune checkpoint inhibitors (ICIs) are becoming increasingly prevalent in the treatment of various cancers due to their ability to reduce tumor mediated T cell death and lengthen the anti-tumor response. One such therapy that is increasingly utilized …

Bonita - Euthynnus Alletteratus Neurocranium, Daniella M. Acosta Reyes, Matthew Mcmanus, Morgan Michalek, David W. Kerstetter

All Scans: Kerstetter Fisheries and Avian Ecology 3D Scan Series

No abstract provided.

Synthesis And Characterization Of Eco-Engineered Hollow Fe2o3/Carbon Nanocomposite Spheres: Evaluating Structural, Optical, Antibacterial, And Lead Adsorption Properties, Islam Gomaa, Nikita Yushin, Mekki Bayachou, Vojislav Stani´, Inga Zinicovscaia

Chemistry Faculty Publications

This work presents a facile mechano-thermal route for the synthesis of carbon-decorated, hollow, mesoporous alpha-Fe2O3 microspheres. Comprehensive characterization (XRD, XPS, FT-IR, SEM/EDX, TGA, zeta-potential) confirmed the formation of phase-pure hematite with nanoscale crystallites (similar to 19 nm), substantial residual surface carbon (similar to 40 wt%) consistent with Fe-O-C linkages, and a positive surface charge (+15.9 mV). The hierarchical hollow/mesoporous architecture enables fast ion transport and provides extensive interior binding sites, resulting in rapid Pb(II) uptake that reaches 92% removal in approximate to 15 min at pH 5.0. The adsorption follows a Langmuir isotherm (q(max) approximate to 70.6 mg/g) and pseudo-second-order …

Editorial: Bridging Inflammation, Oxidative Stress, And Metabolic Dysfunction In Brain Disorders, Ansab Akhtar

School of Medicine Faculty Publications

We present this Special Issue of Brain Sciences, titled "Role of Inflammation, Oxidative Stress, and Metabolic Dysfunction in Neurodevelopmental and Neurodegenerative Diseases: Pharmacological Targets and Therapeutic Interventions", which brings together research and review articles that explore the molecular crosstalk between neuroinflammatory, oxidative stress, and metabolic pathways underlying both neurodegenerative and neurodevelopmental disorders [...].