Digital Commons Network^™

Bisphenol A Affects Neurodevelopmental Gene Expression, Cognitive Function, And Neuromuscular Synaptic Morphology In Drosophila Melanogaster, Chloe Welch, Eden Johnson, Angelina Tupikova, Judith Anderson, Brendan Tinsley, Johnathan Newman, Erin Widman, Adam Alfareh, Alexandra Davis, Lucero Rodriguez, Clayton Visger, Justin P. Miller-Schulze, Wendy Lee, Kimberly Mulligan

Faculty Research, Scholarly, and Creative Activity

Bisphenol A (BPA) is an environmentally prevalent endocrine disrupting chemical that can impact human health and may be an environmental risk factor for neurodevelopmental disorders. BPA has been associated with behavioral impairment in children and a variety of neurodevelopmental phenotypes in model organisms. We used Drosophila melanogaster to explore the consequences of developmental BPA exposure on gene expression, cognitive function, and synapse development. Our transcriptome analysis indicated neurodevelopmentally relevant genes were predominantly downregulated by BPA. Among the misregulated genes were those with roles in learning, memory, and synapse development, as well as orthologs of human genes associated with neurodevelopmental and …

Hope Dies Last: The Progressive Potential And Regressive Reality Of The Antibalkanization Approach To Racial Equality, David Simson

Articles & Chapters

This Article relies on Critical Race Theory concepts and social science research to make an important and timely contribution to a debate in law and public policy that is both longstanding and of immense current importance: What is the relationship between social cohesion on the one hand, and racial equality progress on the other. Events over the last year have put this question into sharp relief. On the one hand, portions of the general public and at least some policymakers have signaled support for the demands of racial justice activists to reduce and eliminate systemic racism after too many tragedies …

Psychophysiological Predictors Of Change In Emotion Dysregulation 6 Months After Traumatic Injury, Jacklynn M. Fitzgerald, Sydney Clare Timmer-Murillo, Claire Sheeran, Hailey Begg, Morgan Christoph, Terri A Deroon-Cassini, Christine L. Larson

Psychology Faculty Research and Publications

Emotional dysregulation that occurs after trauma conveys risk for multiple disorders, including posttraumatic stress disorder, depression, and anxiety. Psychophysiological data (e.g., skin conductance level [SCL]) may be a useful biomarker for quantifying emotion dysregulation given that autonomic nervous system (ANS)-mediated arousal may underlie this feature. In this longitudinal study, we tested whether SCL collected following a single-incident traumatic injury could predict changes in emotion dysregulation over 6 months. Sixty-six adults were recruited from the emergency department; SCL was quantified during an active trauma narrative, in which participants re-told their traumatic event to a research staff member, as well as a …

Cognitive Control Processes In Behavior Therapy For Youth With Tourette’S Disorder, Joseph F. Mcguire, Alexandra Sturm, Emily J. Ricketts, Gabrielle E. Montalbano, Susanna W. Chang, Sandra K. Loo, Douglas W. Woods, James T. Mccracken, John Piacentini

Psychology Faculty Research and Publications

Background

Cognitive control processes are implicated in the behavioral treatment of Tourette’s disorder (TD). However, the influence of these processes on treatment outcomes has received minimal attention. This study examined whether cognitive control processes and/or tic suppression predicted reductions in tic severity and treatment response to behavior therapy.

Method

Fifty-three youth with TD or a pervasive tic disorder participated in a randomized wait list-controlled trial of behavior therapy. Following a baseline assessment to evaluate psychiatric diagnoses, tic severity, and cognitive control processes (e.g., response selection, inhibition, and suppression), youth were randomly assigned to receive eight sessions of behavior therapy ( …

Examining Differences In Parenting Stress, Parenting Efficacy, And Household Context Among Mothers Of Youth With Autism And/Or Adhd, Hillary K. Schiltz, Alana J. Mcvey, Kelsey Gonring, Angela D. Haendel, Christina Murphy, Amy V. Van Hecke, Alyson C. Gerdes

Psychology Faculty Research and Publications

Parents of youth with neurodevelopmental disorders experience unique stressors in family functioning when compared to parents of neurotypical youth. A paucity of research, however, has examined differences in parenting experiences across families of youth with varying neurodevelopmental disorder presentations. This paper focuses on two common and frequently co-occurring conditions: autism spectrum disorder and attention-deficit/hyperactivity disorder (ADHD). In this study, we compared parenting stress, parenting efficacy, and the household context across a sample of 90 mothers of adolescents ages 11–16 years with (1) autism, (2) ADHD, or (3) autism and clinically-elevated ADHD symptoms (Autism + ADHD). Our findings demonstrated differences in …

Vitamin D Deficiency And Its Associated Factors Among Female Migrants In The United Arab Emirates, Fatme Al Anouti, Luai A. Ahmed, Azmat Riaz, William B. Grant, Nadir Shah, Raghib Ali, Juma Alkaabi, Syed M. Shah

All Works

Vitamin D is important for bone health, and vitamin D deficiency could be linked to noncommunicable diseases, including cardiovascular disease. The purpose of this study was to determine the prevalence of vitamin D deficiency and its associated risk factors among female migrants from Philippines, Arab, and South Asian countries residing in the United Arab Emirates (UAE). We used a cross-sectional study to recruit a random sample (N = 550) of female migrants aged 18 years and over in the city of Al Ain, UAE. Vitamin D deficiency was defined as serum 25-hydroxyvitamin D concentrations ≤20 ng/mL (50 nmol/L). We used …

Vitamin D Supplementation And Sleep: A Systematic Review And Meta-Analysis Of Intervention Studies, Myriam Abboud

All Works

Background: Vitamin D deficiency is associated with sleep disorders and poor sleep quality. Whether vitamin D supplementation (VDS) helps resolve these problems remains unclear. Objective: To systematically review the effect of VDS on sleep quantity, quality, and disorders, and perform a meta-analysis of available data. Methods: The reporting of this review followed the PRISMA statement. VDS human interventions studies that reported on sleep quality, quantity, or disorders were included. Medline, CINAHL, EMBASE, PsycInfo, the Cochrane Library, Clinicaltrials.gov, and the ICTRP were searched, in addition to the references of the included articles and previous relevant reviews, without language or time restrictions. …

The Association Between Peptide Hormones With Obesity And Insulin Resistance Markers In Lean And Obese Individuals In The United Arab Emirates, Manal Ali Ahmad, Mirey Karavetian, Carole Ayoub Moubareck, Gabi Wazz, Tarek Mahdy, Koen Venema

All Works

Peptide hormones play a crucial role in body weight and glucose homeostasis. In this study, we aimed to explore this association and recruited 43 obese and 31 age-and sex-matched lean participants. We assessed their body mass index (BMI), waist circumference (WC), waist-to-height ratio (WtHR), percentage body fat (PBF), fasting blood levels of peptide hormones (GLP-1, GLP-2, insulin, leptin, ghrelin, CCK, and PYY), fasting blood sugar (FBS), and Homeostatic Model Assessment of Insulin Resistance (HOMA-IR). We tested the associations between peptide hormones and markers of obesity and insulin resistance (IR) by using the Independent-Samples t-test and Mann-Whitney U test, partial correlation, …

Quantitative Analysis Of Methodological And Environmental Influences On Survival Of Planted Mangroves In Restoration And Afforestation, Daniel Gorman, Mathew A. Vanderklift, Anna Lafratta

Research outputs 2022 to 2026

Mangrove planting has been employed for decades to achieve aims associated with restoration and afforestation. Often, survival of planted mangroves is low. Improving survival might be aided by augmenting the understanding of which planting methods and environmental variables most influence plant survival across a range of contexts. The aim of this study was to provide a global synthesis of the influence of planting methods and background environment on mangrove survival. This was achieved through a global meta-analysis, which compiled published survival rates for the period 1979–2021 and analyzed the influence of decisions about minimum spacing and which life stage to …

Determinant Of Repeat Revascularization Within 5 Years Of Percutaneous Coronary Lntervention At A Tertiary Care Hospital, Karachi: A Matched Case-Control Study, Komal Valliani, Azmina Artani, Iqbal Azam, Javed Tai, M. Masood Kadir

Community Health Sciences

Objective: To determine factors associated with repeat revascularization among adults aged 25 years and above within 5 years of first Percutaneous Coronary Intervention (PCI) at a tertiary care hospital.
Methods: A matched case-control study was conducted through a hospital records review. A total of 90 cases with repeat revascularization and 180 controls without repeat revascularization were included. Data was analyzed using Multiple Conditional Logistic Regression.
Results: The mean age was similar in cases and controls (60.05 ± 10.01 vs 62.20 ± 10.43 years) and sex (male: 77.8% vs. 76.1%). History of being an ever-smoker (40% vs. 25%), overweight (36.3% vs. …

Jagged1/Notch3 Activation Promotes Aortic Hypermuscularization And Stenosis In Elastin Deficiency, Jui M. Dave, Robert Mecham, Et Al

Open Access Publications

Obstructive arterial diseases, including supravalvular aortic stenosis (SVAS), atherosclerosis, and restenosis, share 2 important features: an abnormal or disrupted elastic lamellae structure and excessive smooth muscle cells (SMCs). However, the relationship between these pathological features is poorly delineated. SVAS is caused by heterozygous loss-of-function, hypomorphic, or deletion mutations in the elastin gene (ELN), and SVAS patients and elastin-mutant mice display increased arterial wall cellularity and luminal obstructions. Pharmacological treatments for SVAS are lacking, as the underlying pathobiology is inadequately defined. Herein, using human aortic vascular cells, mouse models, and aortic samples and SMCs derived from induced pluripotent stem cells of …

Fk506-Binding Protein-Like And Fk506-Binding Protein 8 Regulate Dual Leucine Zipper Kinase Degradation And Neuronal Responses To Axon Injury, Bohm Lee, Yeonsoo Oh, Eunhye Cho, Aaron Diantonio, Valeria Cavalli, Jung Eun Shin, Hae Woong Choi, Yongcheol Cho

Open Access Publications

The dual leucine zipper kinase (DLK) is a key regulator of axon regeneration and degeneration in response to neuronal injury; however, regulatory mechanisms of the DLK function via its interacting proteins are largely unknown. To better understand the molecular mechanism of DLK function, we performed yeast two-hybrid screening analysis and identified FK506-binding protein-like (FKBPL, also known as WAF-1/CIP1 stabilizing protein 39) as a DLK-binding protein. FKBPL binds to the kinase domain of DLK and inhibits its kinase activity. In addition, FKBPL induces DLK protein degradation through ubiquitin-dependent pathways. We further assessed other members in the FKBP protein family and found …

Social Isolation And Incident Heart Failure Hospitalization In Older Women: Women's Health Initiative Study Findings, Crystal W Cené, Xiaoyan Iris Leng, Khushnood Faraz, Matthew Allison, Khadijah Breathett, Chloe Bird, Mace Coday, Giselle Corbie-Smith, Randi Foraker, Nkechinyere N Ijioma, Milagros C Rosal, Shawnita Sealy-Jefferson, Tetyana P Shippee, Candyce H Kroenke

Open Access Publications

Background The association of social isolation or lack of social network ties in older adults is unknown. This knowledge gap is important since the risk of heart failure (HF) and social isolation increase with age. The study examines whether social isolation is associated with incident HF in older women, and examines depressive symptoms as a potential mediator and age and race and ethnicity as effect modifiers. Methods and Results This study included 44 174 postmenopausal women of diverse race and ethnicity from the WHI (Women's Health Initiative) study who underwent annual assessment for HF adjudication from baseline enrollment (1993-1998) through …

Transcriptomic Profile Investigations Highlight A Putative Role For Nudt16 In Sepsis, Susie Shih Yin Huang, Darawan Rinchai, Mohammed Toufiq, Basirudeen Syed Ahamed Kabeer, Jessica Roelands, Wouter Hendrickx, Sabri Boughorbel, Davide Bedognetti, Nicholas Van Panhuys, Damien Chaussabel, Mathieu Garand

Open Access Publications

Sepsis is an aberrant systemic inflammatory response mediated by the acute activation of the innate immune system. Neutrophils are important contributors to the innate immune response that controls the infection, but harbour the risk of collateral tissue damage such as thrombosis and organ dysfunction. A better understanding of the modulations of cellular processes in neutrophils and other blood cells during sepsis is needed and can be initiated via transcriptomic profile investigations. To that point, the growing repertoire of publicly accessible transcriptomic datasets serves as a valuable resource for discovering and/or assessing the robustness of biomarkers. We employed systematic literature mining, …

Commissioning A Secondary Dose Calculation Software For A 0.35 T Mr-Linac, Alex T Price, Nels C Knutson, Taeho Kim, Olga L Green

Open Access Publications

Secondary external dose calculations for a 0.35 T magnetic resonance image-guided radiation therapy (MRgRT) are needed within the radiation oncology community to follow safety standards set forth within the field. We evaluate the commercially available software, RadCalc, in its ability to accurately perform monitor unit dose calculations within a magnetic field. We also evaluate the potential effects of a 0.35 T magnetic field upon point dose calculations. Monitor unit calculations were evaluated with (wMag) and without (noMag) a magnetic field considerations in RadCalc for the ViewRay MRIdian. The magnetic field is indirectly accounted for by using asymmetric profiles for calculation. …

Effects Of Methyl Salicylate (Mesa) On The Physiology And Biochemical Characteristics Of Rice Under Salinity Stress At Seedling Stage, Thu Ha Thi Pham, Truong Minh Tuan, Pham Thi Thu Hien, Tran Thi My Hiep, Chau Thi Da

The Philippine Agricultural Scientist

Salt stress negatively affects crop survival, growth, development, and yield. Methyl salicylate (MeSA) is synthesized from salicylic acid (SA) which is a volatile organic compound that is responsible for inducing defense mechanisms in plants and also has a protective role in stress sensitivity. The objective of this study was to examine the effect of different concentrations of methyl salicylate (MeSA) on the physiological and biochemical characteristics of two rice varieties GRIS4 (G1) and GRIS5 (G2) under salt stress at the seedling stage. Five hundred seeds of each variety were treated with different doses of MeSA (0, 0.1, 0.5, and 1.0 …

Effect Of Workers Density On Insect Pest Incidence And Colony Development Of Bumblebees, Bombus Terrestris (L.) (Hymenoptera: Apidae), Marium Fatima, Asim Gulzar, Munir Ahmed, Farid Asif Shaheen, Muhammad Tariq, Tariq Mukhtar

The Philippine Agricultural Scientist

Insect pollination improves essential nutrients and qualities of pollinating plants. Approximately 90% of flowering plants and 35% of crops require insect pollination. Bees play a vital role in pollination in natural and agricultural systems. Managed bees have extensively been used for pollination. Unfortunately, the native bee population has been waning globally. Commercial bee-rearing experiences different rearing problems i.e. food, environment, and spatial conditions within colonies. In this research, the impact of different densities of workers within colonies of Bombus terrestris L. was observed on colony development and pest incidence. Different worker densities i.e. 60-70, 80-90,110-120 and 140-150, respectively, were maintained …

Opposition To Renewable Energy Facilities In The United States: March 2022 Edition, Hillary Aidun, Jacob Elkin, Radhika Goyal, Kate Marsh, Neely Mckee, Maris Welch, Leah Adelman, Shane Finn

Sabin Center for Climate Change Law

Achieving lower carbon emissions in the United States will require developing a very large number of wind, solar, and other renewable energy facilities, as well as associated storage, distribution, and transmission, at an unprecedented scale and pace. Although host community members are often enthusiastic about renewable energy facilities’ economic and environmental benefits, local opposition often arises. This report updates a previous Sabin Center report, published in February 2021, and documents local restrictions on and opposition to siting renewable energy projects for the period from 1995 to early 2022. Importantly, the authors do not make normative judgments as to the legal …

Identifying Causative Microorganisms In Left Ventricular Assist Device Infections As A Guide For Developing Bacteriophage Therapy, Ishan Kamat, Harveen Lamba, Casey Hines-Munson, Samuel Hudson, Kenneth Liao, Kenneth L Muldrew, Sabrina Green, Austen Terwilliger, Heidi B Kaplan, Robert F Ramig, Anthony Maresso, Barbara W Trautner

Faculty, Staff and Students Publications

BACKGROUND: As more left ventricular-assist devices (LVADs) are implanted, multidrug-resistant LVAD infections are becoming increasingly common, partly due to bacterial biofilm production. To aid in developing bacteriophage therapy for LVAD infections, we have identified the most common bacterial pathogens that cause LVAD driveline infections (DLIs) in our heart transplant referral center.

MATERIALS AND METHODS: We studied a retrospective cohort of patients who received LVADs from November 2003 to August 2017 to identify the common causative organisms of LVAD infection. We also studied a prospective cohort of patients diagnosed with DLIs from October 2018 to May 2019 to collect bacterial strains …

Apgar Values Lower Than 7 Associated With Mortality In Premature Newborns: A Retrospective Study, Nayeri Reyes-Saavedra, Patricia C. Castelán-Villagrana, Ivette Mata-Maqueda, Juan C. Solís-Sáinz

Saudi Medical Journal

Objectives: To determine the risk factors associated with mortality in premature newborns (PNB). Methods: An observational, descriptive, and retrospective study, carried out at the General Hospital of San Juan del Rio, Queretaro, Mexico. The medical records of PNB admitted to the Neonatal Intensive Care Unit from January until December 2018 were studied. Results: A total of 136 PNB were included (74 males and 62 females) of whom 16 (11.7%) died (9 males and 7 females). A correlation was observed between gestational age and birth weight with Apgar values at 1 and 5 minutes (r=0.37, p <0.001). A lower birth weight was found in premature infants with infectious diseases, as well as a lower gestational age in relation to respiratory diseases ( p <0.0001). The PNB with Apgar values lower than 7 points at 1 and 5 minutes were more likely to die ( p <0.0001). The PNB with very low birth weight (1-1.49 kg), with less than 28 weeks of gestation, and with infectious pathology showed more probabilities of dying ( p <0.05). Conclusion: Apgar values lower than 7 points in the PNB are associated with the presence of infectious diseases and mortality. Likewise, a lower gestational age represents a lower birth weight, with a higher risk for respiratory and infectious diseases, and consequently an elevated mortality.

Surgical Outcomes Of Severe Spinal Deformities Exceeding 100° Or Treated By Vertebral Column Resection (Vcr). Does Implant Density Matter?: An Observational Study Of Deformity Groupings, Oheneba Boachie-Adjei, Henry Ofori Duah, Arthur Sackeyfio, Kwadwo P. Yankey, Lawrence G. Lenke, Paul Sponseller, Amer F. Samdani, Daniel J. Sucato, Brenda Sides, Peter Newton, Suken Shah, Harry Akoto, Munish Gupta, Fox Pediatric Spinal Deformity Study

College of Nursing Faculty Research and Publications

Study design

Prospective multicenter international observational study.

Objective

To investigate the effect of implant density on clinical outcomes in complex pediatric spine reconstruction.

Summary of background data

Implant density in spine deformity surgery has been a subject of much debate with some authors advocating higher density for better correction. Few studies have looked at the effect of implant density on severe curves > 100 deg or treated with vertebral column resection (VCR).

Methods

250/311 pts with 2-year f/u enrolled in the FOX pediatric database from 17 international sites were queried for the impact of implant density and surgical outcomes. Patients were …

Comorbid Patterns In The Homeless Population: A Theoretical Model To Enhance Patient Care, Kanwalgeet Hans, Luke Mike, Robert Heidel, Paula Benavides, Robert Arnce, Jan Talley

Faculty and Staff Publications

Introduction:

From the perspective of social determinants, homelessness perpetuates poor health and creates barriers to effective chronic disease management, necessitating frequent use of emergency department (ED) services. In this study we developed a screening algorithm (checklist) from common comorbidities observed in the homeless population in the United States. The result was a theoretical screening tool (checklist) to aid healthcare workers in the ED, including residents, medical students, and other trainees, to provide more efficacious treatment and referrals for discharge.

Methods:

In this retrospective cohort study we used the Nationwide Emergency Department Sample (NEDS) to investigate comorbidities and ED utilization patterns …

The Evolutionary History Of An Accidental Model Organism, The Leopard Gecko Eublepharis Macularius (Squamata: Eublepharidae), Ishan Agarwal, Aaron M. Bauer, Tony Gamble, Varad B. Giri, Daniel Jablonski, Akshay Khandekar, Pratyush P. Mohapatra, Rafaqat Masroor, Anurag Mishra, Uma Ramakrishnan

Biological Sciences Faculty Research and Publications

The leopard gecko, Eublepharis macularius, is a widely used model organism in laboratory and experimental studies. The high phenotypic diversity in the pet trade, the fact that the provenance of different breeding lines is unknown, and that distinct Eublepharis species are known to hybridize, implies that the continued use of E. macularius as a model requires clarity on the origin of the lineages in the pet trade. We combine multi-locus sequence data and the first range-wide sampling of the genus Eublepharis to reconstruct the evolutionary history of the Eublepharidae and Eublepharis, with an updated time-tree for the Eublepharidae. …

Convergent Developmental Patterns Underlie The Repeated Evolution Of Adhesive Toe Pads Among Lizards, Aaron H. Griffing, Tony Gamble, Martin J. Cohn, Thomas J. Sanger

Biological Sciences Faculty Research and Publications

How developmental modifications produce key innovations, which subsequently allow for rapid diversification of a clade into new adaptive zones, has received much attention. However, few studies have used a robust comparative framework to investigate the influence of evolutionary and developmental constraints on the origin of key innovations, such as the adhesive toe pad of lizards. Adhesive toe pads evolved independently at least 16 times in lizards, allowing us to examine whether the patterns observed are general evolutionary phenomena or unique, lineage-specific events. We performed a high-resolution comparison of plantar scale development in 14 lizard species in Anolis and geckos, encompassing …

The Modern Homeland Security Struggle: Divisive Disinformation, Stephen H. Dickerson

Doctoral Dissertations and Projects

This research introduces the concepts surrounding disinformation and misinformation campaigns, along with their standing as significant homeland security threats. The piece starts with a brief introduction that focuses in on current examples of how these campaigns are being utilized, to include introductory discussion of theory and strategy. This is followed by a literature review, which explores a wide variety of disinformation related topics, including pieces that help in defining the matter and others that introduce related psychological theories. In addition to the literature that discusses real world examples, current instances are discussed, allowing for a more comprehensive view of not …

Can A Lack Of Early Attachment To A Primary Caregiver Contribute To Aged-Out Kinship Foster Youth Sexual Employment?, Judith M. Malik

Doctoral Dissertations and Projects

This study investigated the relationship between lack of early attachment with a primary caregiver and survival sex employment in aged-out kinship care youth. Literature has shown that multiple situations have occurred to AFCY. While in kinship care, youth may have experienced physical abuse, sexual abuse, neglect, inappropriate discipline, and exposure to domestic violence, homicide, and pornography. Of the estimated 250,000 children who exited kinship care in 2018, 49% were reunited with their natural parent or primary caretaker, 25% were adopted, 11% went to live with a guardian, 7% were aged out, 7% went to live with another relative, and 1% …

The Experiences Of African American Graduate Students Attending Colleges Of Chiropractic: A Hermeneutical Phenomenology, Darren De'un Howland

Doctoral Dissertations and Projects

The purpose of this hermeneutical phenomenological study is to discover and interpret the campus experiences of African American graduate students attending colleges of chiropractic in the United States. A sense of belonging within a campus environment is essential to all students that encounter a university. The campus environment has an important role in the retention of African American students. The theory guiding this study is the Culturally Engaging Campus Environment Model which examines cultural engagement within the campus environment. The central question leading this research study asks, “What are the lived experiences of African American graduate students attending colleges of …

Learning Loss In Passage Reading Fluency For Elementary Students During Covid-19 School Closure, David Neil Stone

Doctoral Dissertations and Projects

The onset of the COVID-19 pandemic in 2020 caused public schools across the United States to suddenly close and interrupt face-to-face instruction for all students for a sustained period of time. It remains uncertain the total effect of the prolonged closure on student learning. This study provides a historical research review of the effect of previous school closures, such as traditional summer breaks and explores the phenomenon of learning loss that occurs when instruction is paused. This causal-comparative study examined the effect on passage reading fluency and reading comprehension of fourth grade elementary students following an unprecedented 24-week disruption of …

Dmp1 Lineage Cells Contribute Significantly To Periosteal Lamellar Bone Formation Induced By Mechanical Loading But Are Depleted From The Bone Surface During Rapid Bone Formation, Taylor L Harris, Matthew J Silva

2020-Current year OA Pubs

Previous work has shown that osteoprogenitor cells (Prx1+) and pre-osteoblasts (Osx+) contribute to mechanical loading-induced bone formation. However, the role of mature Dmp1-expressing osteoblasts has not been reported. In this study we assessed the contribution of osteoblast lineage cells to bone formation at an early time point following mechanical loading (day 8 from onset of loading). We labeled Osx-expressing and Dmp1-expressing cells in inducible Osx and Dmp1 reporter mice (iOsx-Ai9, iDmp1-Ai9), respectively, 3 weeks before loading. Mice were then loaded daily for 5 days (days 1-5) and were dosed with 5-ethynyl-2'-deoxyuridine (EdU) in their drinking water until euthanasia on day …

A Tail Of Plumage Colouration: Disentangling Geographic, Seasonal And Dietary Effects On Plumage Colour In A Migratory Songbird, Sean M. Mahoney, Matthew W. Reudink, Andrea Contina, Kelly A. Roberts, Veronica T. Schabert, Emily G. Gunther, Kristen M. Covino

School of Integrative Biological & Chemical Sciences Faculty Publications

Plumage ornamentation in birds serves critical inter- and intra-sexual signaling functions. While carotenoid-based plumage colouration is often viewed as a classic condition-dependent sexually selected trait, plumage colouration can be influenced by a wide array of both intrinsic and extrinsic factors. Understanding the mechanisms underlying variation in colouration is especially important for species where the signaling function of ornamental traits is complex or when the literature is conflicting. Here, we examined variation in the yellow/orange tail feathers of American redstarts Setophaga ruticilla passing through two migratory stopover sites in eastern North America during both spring and fall migration to assess the …