Digital Commons Network^™

Political Ecology For Environmental And Life Sciences Maf-Saf 547, Joanna Burkhardt

Library Impact Statements

No abstract provided.

Medical School Watercooler Newsletter - March 3, 2022, Lindsey Lyle

Watercooler Newsletter

This is the March 3, 2022 edition of the Frederick P. Whiddon College of Medicine's newsletter - Watercooler.

Contents include:

• USA Health physician-scientist awarded $1.9 million grant to study acidosis in the lungs
• Class of 2022 to celebrate Match Day
• Distinguished Scientist Seminars to return March 10
• USA College of Medicine alumnus appointed Mobile County Health Department’s health officer
• MAA Reunion set for June at the Grand Hotel
• Meet A Med Student: Natalie Kidd

Judicial Depictions Of Responsibility And Risk: The Erasure Of State Accountability In Canadian Sentencing Judgments Involving Indigenous People, Sarah Jane Nussbaum

PhD Dissertations

This dissertation is set within the context of Canadas mass imprisonment of Indigenous people and centres on a critical evaluation of reported sentencing judgments. In particular, the dissertation examines some of the ways in which sentencing judges both draw attention to, and obscure, state accountability. The dissertation demonstrates that sentencing judges erase the role of the state in the criminalization of Indigenous people and in the construction of Indigenous people as risky. The result is that sentencing judgments rationalize and support the re-entrenchment, rather than the redressing, of the states oppression of Indigenous people. The dissertation is theoretical and descriptive, …

Imidazole-Based Ph-Sensitive Convertible Liposomes For Anticancer Drug Delivery, Ruiqi Huang, Vijay Gyanani, Shen Zhao, Yifan Lu, Xin Guo

School of Pharmacy Faculty Articles

In efforts to enhance the activity of liposomal drugs against solid tumors, three novel lipids that carry imidazole-based headgroups of incremental basicity were prepared and incorporated into the membrane of PEGylated liposomes containing doxorubicin (DOX) to render pH-sensitive convertible liposomes (ICL). The imidazole lipids were designed to protonate and cluster with negatively charged phosphatidylethanolamine-polyethylene glycol when pH drops from 7.4 to 6.0, thereby triggering ICL in acidic tumor interstitium. Upon the drop of pH, ICL gained more positive surface charges, displayed lipid phase separation in TEM and DSC, and aggregated with cell membrane-mimetic model liposomes. The drop of pH also …

Stem Cell Architecture Drives Myelodysplastic Syndrome Progression And Predicts Response To Venetoclax-Based Therapy, Irene Ganan-Gomez, Hui Yang, Feiyang Ma, Guillermo Montalban-Bravo, Natthakan Thongon, Valentina Marchica, Guillaume Richard-Carpentier, Kelly Chien, Ganiraju Manyam, Feng Wang, Ana Alfonso, Shuaitong Chen, Caleb Class, Rashmi Kanagal-Shamanna, Justin P. Ingram, Yamini Ogoti, Ashley Rose, Sanam Loghavi, Pamela Lockyer, Benedetta Cambo, Muharrem Muftuoglu, Sarah Schneider, Vera Adema, Michael Mclellan, John Garza, Matteo Marchesini, Nicola Giuliani, Matteo Pellegrini, Jing Wang, Jason Walker, Ziyi Li, Koichi Takahashi, Joel D. Leverson, Carlos Bueso-Ramos, Michael Andreeff, Karen Clise-Dwyer, Guillermo =Garcia-Manero, Simona Colla

Scholarship and Professional Work – COPHS

Myelodysplastic syndromes (MDS) are heterogeneous neoplastic disorders of hematopoietic stem cells (HSCs). The current standard of care for patients with MDS is hypomethylating agent (HMA)-based therapy; however, almost 50% of MDS patients fail HMA therapy and progress to acute myeloid leukemia, facing a dismal prognosis due to lack of approved second-line treatment options. As cancer stem cells are the seeds of disease progression, we investigated the biological properties of the MDS HSCs that drive disease evolution, seeking to uncover vulnerabilities that could be therapeutically exploited. Through integrative molecular profiling of HSCs and progenitor cells in large patient cohorts, we found …

Curriculum Subcommittee Minutes March 3, 2022, Utah State University

Educational Policies Committee

• Approval of 3 February 2022 Minutes
• Program Proposals
• Semester Course Approval Reviews
• Other Business
• Adjourn: 2:49 pm

Curriculum Subcommittee Meeting Agenda, March 3, 2022, Utah State University

Educational Policies Committee

Agenda

• Approval of 3 February 2022 Minutes
  
• Program Proposals
• Semester Course Approval Reviews https://usu.curriculog.com/
• College of Agriculture and Applied Sciences AVTE = 27
• Emma Eccles Jones College of Education and Human Services COMD = 11 ELED = 1 HDFS = 1 KHS = 1 ITLS = 12 SPED = 2 TEAL = 1
• College of Humanities and Social Sciences SOCA = 1 IELI = 2
• S.J. & Jessie E. Quinney College of Natural Resources WILD = 2
• Other Business

Educational Policies Committee Agenda, March 3, 2022, Utah State University

Educational Policies Committee

Agenda

• Approval of 3 February 2022 Minutes.
  
• Subcommittee Reports
• Curriculum Subcommittee (Matthew Sanders) Course Approvals – 61
• Academic Standards Subcommittee (Renee Galliher) Minutes – No meeting
• General Education Subcommittee (Lee Rickords) Minutes – January 18, 2022 and February 15, 2022
• Other Business
• Department of Landscape Architecture and Environmental Planning CIP Code Change

The Rattler (Volume 110, Issue 6), St. Mary's University

The Rattler (Previous issues)

Founded in 1919, The Rattler is the student voice of St. Mary’s University in San Antonio, Texas. The newspaper documents campus life, academic and social issues, student opinion, and local and national events as they relate to the University community. Content typically includes news articles, editorial commentary, arts and culture coverage, sports reporting, and advertisements.

An Interactive Game With Virtual Reality Immersion To Improve Cultural Sensitivity In Healthcare, Paul J. Hershberger, Yong Pei, Timothy N. Crawford, Sabrina M. Neeley, Thomas Wischgoll, Dixit B. Patel, Miteshkumar M. Vasoya, Angie Castle, Sankalp Mishra, Lahari Surapaneni, Aman A. Pogaku, Aishwarya Bositty, Todd Pavlack

Computer Science and Engineering Faculty Publications

Purpose: Biased perceptions of individuals who are not part of one’s in-groups tend to be negative and habitual. Because health care professionals are no less susceptible to biases than are others, the adverse impact of biases on marginalized populations in health care warrants continued attention and amelioration. Method: Two characters, a Syrian refugee with limited English proficiency and a black pregnant woman with a history of opioid use disorder, were developed for an online training simulation that includes an interactive life course experience focused on social determinants of health, and a clinical encounter in a community health center utilizing virtual …

Covid-19 In Cns And Pns: Basic And Clinical Focus On The Mechanisms Of Infection And New Tools For The Therapeutic Approach, Jorge Matias-Guiu, Jordi A. Matias-Guiu, Carmen Garrido, Genaro Pimienta, Patricio F. Reyes, Abdul Mannan Baig, Ulises Gomez-Pinedo

Department of Biological & Biomedical Sciences

No abstract provided.

Aerosolization Of Catalytic Rna For Prebiotic Transport And In Situ Reactivity, Brennan Roland Farrell

Dissertations and Theses

Recent theoretical and experimental work suggests that aqueous aerosols in the early Earth's atmosphere might have been an essential component to the development of life. These complex droplets would have served to compartmentalize emerging biomolecules, thereby concentrating them, increasing reactivity, and facilitating transport and exchange between ocean and atmosphere. This project tests an underexplored but potentially important environmental paradigm for the RNA world hypothesis of prebiotic evolution, probing the effects of aerosolization on catalytic RNA using a model ribozyme. Here we demonstrate the successful transport and in situ self-assembly of the Azoarcus ribozyme from multiple independent fragments via a laboratory-constructed …

Faculty Senate Chronicle March 3, 2022, Heather M. Loughney

The University of Akron Faculty Senate Chronicle

No abstract provided.

Gene-Based Association Tests Using Gwas Summary Statistics And Incorporating Eqtl, Xuewei Cao, Xuexia Wang, Shuanglin Zhang, Qiuying Sha

Michigan Tech Publications, Part 1

Although genome-wide association studies (GWAS) have been successfully applied to a variety of complex diseases and identified many genetic variants underlying complex diseases via single marker tests, there is still a considerable heritability of complex diseases that could not be explained by GWAS. One alternative approach to overcome the missing heritability caused by genetic heterogeneity is gene-based analysis, which considers the aggregate effects of multiple genetic variants in a single test. Another alternative approach is transcriptome-wide association study (TWAS). TWAS aggregates genomic information into functionally relevant units that map to genes and their expression. TWAS is not only powerful, but …

Event-Related Correlates Of Evolving Trust Evaluations, Ariel W. Snowden, Allison S. Hancock, Catalin V. Buhusi, Christopher M. Warren

Psychology Student Research

Accurate decisions about whether to trust someone are critical for adaptive social behavior. Previous research into trustworthiness decisions about face stimuli have focused on individuals. Here, decisions about groups of people are made cumulatively on the basis of sequences of faces. Participants chose to either increase or withdraw an initial investment in mock companies based on how trustworthy the company representatives (face stimuli) appeared. Companies were formed using participant trust ratings from the previous week, to create strong trustworthy, weak trustworthy, weak untrustworthy, and strong untrustworthy companies. Participants made faster, more accurate decisions for companies carrying stronger evidence (e.g., faces …

Uncertainty And Unrest: A Collaborative Pedagogical Response To Pandemics, Protests, And Policy, Jodi Benenson, Tara Kolar Bryan, Carol Ebdon, Theresa Glanz, James Harrold, Thomas Jamieson, Njoki Mwarumba

Public Administration Faculty Publications

This article presents the pedagogical, observational, and empirical findings from a social equity centered team-taught course that served as an effective learning approach for both students and faculty during a time of great uncertainty and unrest in 2020. The article begins by describing the context for why this course was offered, outlining the need to use a collaborative teaching approach that centers social equity and interdisciplinary expertise when issues such as a global pandemic and racial injustice arise. The authors then describe the methodology and findings associated with surveying students and faculty members who were engaged with the course and …

The Effects Of Curricular Change On Student Learning And Well-Being In Biomedical And Clinical Education, Rachel Jalaire Tomco Novak

Theses and Dissertations

The implementation of curriculum change, and innovative pedagogical theory, can help educators and administrators in higher education further the learning gains of students in the sciences. But the introduction of new methods of teaching, or curricular restructuring, can be interpreted by students differently, potentially affecting students' emotional states as well as their relationships with peers. To support not only the learning of students, but also their emotional and social well-being, pedagogical and curricular theory should be enacted in ways that take into consideration the full scope of the student experience. In this dissertation, the implementation of curriculum and pedagogical theory, …

Developing A Method For Quantifying Hip Joint Angles And Moments During Walking Using Neural Networks And Wearables, Megan V. Mccabe, Douglas W. Van Citters, Ryan M. Chapman

Kinesiology Faculty Publications

Quantifying hip angles/moments during gait is critical for improving hip pathology diagnostic and treatment methods. Recent work has validated approaches combining wearables with artificial neural networks (ANNs) for cheaper, portable hip joint angle/moment computation. This study developed a Wearable-ANN approach for calculating hip joint angles/moments during walking in the sagittal/frontal planes with data from 17 healthy subjects, leveraging one shin-mounted inertial measurement unit (IMU) and a force-measuring insole for data capture. Compared to the benchmark approach, a two hidden layer ANN (n = 5 nodes per layer) achieved an average rRMSE = 15% and R²=0.85 across outputs, subjects …

Edney Works To Widen The Ladder Of Opportunity For All, J. B. Clark

University of Mississippi News

New assistant vice chancellor has helped increase student access to university

Faculty Senate Chronicle March 3, 2022, Heather M. Loughney

The University of Akron Faculty Senate Chronicle

No abstract provided.

Challenges Of The Industrial Revolution Era 1.0 To 5.0 : University Digital Library In Indoensia, Merlin Apriliyanti, Ilham M

Library Philosophy and Practice (e-journal)

This study explains the development of the world of libraries to establish a very close relationship with the world of information technology. For this reason, facilities and infrastructure are needed to facilitate data and information retrieval quickly and accurately. Facing the challenges of the Industrial Revolution 5.0 era by utilizing information technology, libraries must also adapt to the times. Because the library has an important role, among others, as a source of information and the development of knowledge. Used libraries are still conventional to be converted into digital libraries. In essence, this development represents the desire of library users for …

Understanding The Microbial Biogeography Of Ancient Human Dentitions To Guide Study Design And Interpretation, Zandra Fagernäs, Domingo C. Salazar-Garcia, Maria Hadar Uriarte, Azucena Avilés Fernández, Amanda G. Henry, Joaquín Lomba Maurandi, Andrew T. Ozga, Irina M. Velsko, Christina Warinner

Biology Faculty Articles

The oral cavity is a heterogeneous environment, varying in factors such as pH, oxygen levels, and salivary flow. These factors affect the microbial community composition and distribution of species in dental plaque, but it is not known how well these patterns are reflected in archaeological dental calculus. In most archaeological studies, a single sample of dental calculus is studied per individual and is assumed to represent the entire oral cavity. However, it is not known if this sampling strategy introduces biases into studies of the ancient oral microbiome. Here, we present the results of a shotgun metagenomic study of a …

Clinically Adjudicated Deceased Donor Acute Kidney Injury And Graft Outcomes, Sherry G Mansour, Nadeen Khoury, Ravi Kodali, Sarthak Virmani, Peter P Reese, Isaac E Hall, Yaqi Jia, Yu Yamamoto, Heather R Thiessen-Philbrook, Wassim Obeid, Mona D Doshi, Enver Akalin, Jonathan S Bromberg, Meera N Harhay, Sumit Mohan, Thangamani Muthukumar, Pooja Singh, Francis L Weng, Dennis G Moledina, Jason H Greenberg, Francis P Wilson, Chirag R Parikh

Department of Medicine Faculty Papers

Background: Acute kidney injury (AKI) in deceased donors is not associated with graft failure (GF). We hypothesize that hemodynamic AKI (hAKI) comprises the majority of donor AKI and may explain this lack of association.

Methods: In this ancillary analysis of the Deceased Donor Study, 428 donors with available charts were selected to identify those with and without AKI. AKI cases were classified as hAKI, intrinsic (iAKI), or mixed (mAKI) based on majority adjudication by three nephrologists. We evaluated the associations between AKI phenotypes and delayed graft function (DGF), 1-year eGFR and GF. We also evaluated differences in urine biomarkers among …

Human Endothelial Cells Promote Arsenic-Transformed Lung Epithelial Cells To Induce Tumor Growth And Angiogenesis Through Interleukin-8 Induction, Lei Zhao, Yi-Fang Wang, Jie Liu, Bing-Hua Jiang, Ling-Zhi Liu

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Arsenic exposure is associated with lung cancer. Angiogenesis is essential for tumor development. However, the role and mechanism of human vascular endothelial cells in tumor growth and angiogenesis induced by arsenic-transformed bronchial epithelial (As-T) cells remain to be elucidated. In this study, we found that endothelial cells significantly increased As-T cell-induced tumor growth compared to those induced by As-T cells alone. To understand the molecular mechanism, we found that endothelial cells co-cultured with As-T cells or cultured in conditioned medium (CM) prepared from As-T cells showed much higher cell migration, proliferation, and tube formation compared to those co-cultured with BEAS-2B …

Can The Concepts Of Energy And Psychological Energy Enrich Our Understanding Of Psychosocial Adaptation To Traumatic Experiences, Chronic Illnesses And Disabilities?, Hanoch Livneh

Counselor Education Faculty Publications and Presentations

The aim of this paper is to familiarize the reader with the concept of psychological energy (PE), and the role it plays in deepening our understanding of psychosocial adaptation to traumatic life events and, more pointedly, the onset of chronic illness and disability (CID). In order to implement this aim, the following steps were undertaken: First, a brief historical review of the nature of energy, force and action, as traditionally conceived in the field of physics, is provided. Second, an overview of PE is presented, with a shared emphasis on both its historical underpinnings and its present conceptualizations in the …

Albumin Knockout Mice Exhibit Reduced Plasma Free Fatty Acid Concentration And Enhanced Insulin Sensitivity, Afsoun Abdollahi, Brianna N. Dowden, Kimberly K. Buhman, Alyssa S. Zembroski, Gregory C. Henderson

Purdue University Libraries Open Access Publishing Fund

Circulating albumin is expected to play a significant role in the trafficking of plasma free fatty acids (FFA) between tissues, such as FFA transfer from adipose tissue to the liver. However, it was not yet known how disrupting FFA binding to albumin in circulation would alter lipid metabolism and any resulting impacts upon control of glycemia. To improve understanding of metabolic control, we aimed to determine whether lack of serum albumin would decrease plasma FFA, hepatic lipid storage, whole body substrate oxidation, and glucose metabolism. Male and female homozygous albumin knockout mice and C57BL/6J wild type controls, each on a …

All Aboard For Ocean Literacy: Marine Outdoor Environmental Learning In The South West Of England, A Morgan, J Hepburn

Plymouth Institute of Education

No abstract provided.

Vitamin D Supplementation For The Treatment Of Depressive Symptoms In Women With Type 2 Diabetes: A Randomized Clinical Trial, Sue Penckofer Phd, Monique Ridosh, William Howard Adams, Meghan Grzesiak, Jennifer Woo, Mary Byrn, Joanne Kouba Phd, Rdn, Ldn, Patricia M. Sheean, Colleen Kordish, Ramon Durazo-Arvizu, Diane Wallis, Mary Ann Emanuele, Angelos Halaris

Nursing: School of Nursing Faculty Publications and Other Works

Aim. To determine the efficacy and safety of vitamin D₃ supplementation in reducing depressive symptoms in women with type 2 diabetes (T2D), depression, and low vitamin D. Methods. In this double-blind randomized active comparator-controlled trial, women with significant depressive symptoms as assessed by the Center for Epidemiologic Studies Depression (CES-D) scale received weekly oral vitamin D₃ supplementation (50,000 IU) or an active comparator (5,000 IU) for 6 months. Assessments of vitamin D, 25-hydroxyvitamin D [25 (OH) D], and depression were measured at baseline, 3 months, and 6 months. Results. A total of 129 women were …

March 2022 Faculty Senate Packet, University Of Nebraska At Kearney Faculty Senate

Faculty Senate Packets

No abstract provided.

On The Importance Of The Newborn Stage When Learning Patterns With The Spatial Pooler, D Dobric, A Pech, B Ghita, T Wennekers

School of Engineering, Computing and Mathematics

Hierarchical Temporal Memory (HTM-CLA) - Spatial Pooler (SP) is a Cortical Learning Algorithm for learning inspired by the neocortex. It is designed to learn the spatial pattern by generating the Sparse Distributed Representation code (SDR) of the input. It encodes the set of active input neurons as SDR defined by the set of active neurons organized in groups called mini-columns. This paper provides additional findings extending the previous work, that demonstrates how and why the Spatial Pooler forgets learned SDRs in the training progress. The previous work introduced the newborn stage of the algorithm, which takes a control of the …