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Relationship Of Microplastics To Body Size For Two Estuarine Fishes, Ahmed K. Gad, Stephen R. Midway

Faculty Publications

No abstract provided.

Gingival Transcriptome Of Innate Antimicrobial Factors And The Oral Microbiome With Aging And Periodontitis, Jeffrey L. Ebersole, Sreenatha Kirakodu, Linh Nguyen, Octavio A. Gonzalez

Dental Medicine Faculty Research

The epithelial barrier at mucosal sites comprises an important mechanical protective feature of innate immunity, and is intimately involved in communicating signals of infection/tissue damage to inflammatory and immune cells in these local environments. A wide array of antimicrobial factors (AMF) exist at mucosal sites and in secretions that contribute to this innate immunity. A non-human primate model of ligature-induced periodontitis was used to explore characteristics of the antimicrobial factor transcriptome (n = 114 genes) of gingival biopsies in health, initiation and progression of periodontal lesions, and in samples with clinical resolution. Age effects and relationship of AMF to the …

Keynote Address: Unlocking Africa’S Potential In A Time Of Competition Between Rising And Global Powers, Landry Signé

Proceedings: 2022 Global Voices on the University of Dayton Campus

Trade and investment are not just about money and prosperity. They also bring and support peace, stability, and security. In my book Unlocking Africa’s Business Potential, I explore key trade and investment trends, opportunities, challenges, and strategies that illustrate the tremendous potential of Africa and explain the complex competition between emerging and established powers on the continent. The following key trends are critical for policymaking, given their implications for trade investment, economic transformation, inclusive prosperity, and geopolitical dynamics in a time of competition between rising and global powers.

Adverse Childhood Experiences And Sleep Difficulties Among Young Adult College Students, Larisa D. Albers, Timothy J. Grigsby, Stephanie M. Benjamin, Christopher J. Rogers, Jennifer B. Unger, Myriam Forster

Environmental & Global Health Faculty Research

Although adverse childhood experiences (traumatic events such as maltreatment and household dysfunction) are associated with increased risk for sleep difficulties among adults, the association between adverse childhood experiences and poor sleep health among young adult college populations is understudied. This study examined the adverse childhood experience–sleep health (self-reported sleep difficulty and diagnosis of insomnia or “other” sleep disorder) association among college students. Data are from the 2018/2019 American College Health Association-National College Health Assessment II (ACHA-NCHA-II) survey administered at public universities in California (n = 3606) and Texas (n = 407). Logistic regression models investigated the relative effect of adverse …

Possessing Intangibles, João Marinotti

Northwestern University Law Review

The concept of possession is currently considered inapplicable to intangible assets, whether data, cryptocurrency, or NFTs. Under this view, intangible assets categorically fall outside the purview of property law’s foundational doctrines. Such sweeping conclusions stem from a misunderstanding of the role of possession in property law. This Article refutes the idea that possession constitutes—or even requires—physical control by distinguishing possession from another foundational concept, that of thinghood. It highlights possession’s unique purpose within the property process: conveying the status of in rem claims. In property law, the concept of possession conveys to third parties the allocation of property rights and …

Intrathecal And Epidural Dexmedetomidine For Obstetric Patients, Sarah Tobias, Addison Hohner

Doctor of Nursing Practice Projects

The use of dexmedetomidine in spinals and epidurals can be beneficial for obstetric patients. The combination of dexmedetomidine with local anesthetics for neuraxial anesthesia potentiates the effect of the blockade while eliminating the undesirable side effects associated with opioid administration. This project used a non-experimental, pre-test/post-test design to assess key stakeholders' current use and intended future use of dexmedetomidine in neuraxial anesthesia for obstetrical patients. The goal of this project was to review current evidence-based literature regarding the use of dexmedetomidine as a neuraxial adjunct for obstetric anesthesia. The aim of this project was to summarize the results of the …

Undergraduate Session Iiic Natural Sciences: Presentation 4 - Development Of The Pertussis Vaccine, Chase Mckinney

Life of the Scholar Multidisciplinary Conference

An overview of pertussis and a history of the vaccine

Undergraduate Session Iiia English: Presentation 3 - I Work Alone: Fatherhood And Masculinity In Batman Comics, Claire Allen

Life of the Scholar Multidisciplinary Conference

No abstract provided.

Undergraduate Session Iic Natural Sciences: Presentation 1 - A Survey Of Undocumented Species In Cleveland County, North Carolina (Poster), Cullen Fields

Life of the Scholar Multidisciplinary Conference

Cleveland County's species are not as well documented as surrounding counties. This study focused on identifying various species throughout the county to help create a more accurate measure of the species located within its borders.

Rising Demand For Meat And Milk In Developing Countries: Implications For Grasslands-Based Livestock Production, C. L. Delgado

IGC Proceedings (1977-2023)

Key points

1. Meat and milk consumption in developing countries has grown three times as fast as in developed countries over the past 30 years.

2. By 2020, developing countries will consume 72 million metric tons (mmt) more meat and 152 mmt more milk compared to 2002/3, dwarfing developed-country increases of 9 mmt for meat and 18 mmt for milk.

3. Ruminant livestock will account for 27% of the increase in global meat consumption between 2003 and 2020, up from 23% over the previous two decades.

4. The inflation-adjusted prices of livestock and feed grains are expected to fall only …

Grassland In Ireland And The Uk, Myles Rath, S. Peel

IGC Proceedings (1977-2023)

Key points

1. Grassland is the dominant land use option in Ireland and the UK, and is characterised by a long growing season.

2. Dynamic, interactive systems of grassland management have been developed which combine high grass dry matter intakes with good sward quality. In the better grassland areas milk yields in excess of 7000 kg/cow are attainable with low levels of concentrate supplementation.

3. In the times to come, measures to protect the environment will constrain stocking rates, and fertiliser and manure use on intensive grassland enterprises.

4. A high proportion of beef and sheep farms participate in voluntary, …

From Family Storytelling To Emancipatory Knowing: Bearing Witness To The Resistance Of Black Women Leaders In Higher Education, Eboni Sterling

Dissertations

We, in the Black community, have preserved our existence and histories through storytelling. The blessing of stories passed from one generation to the next serves as survival signposts. Amidst this tradition, ongoing dominant narratives work to mischaracterize and dehumanize members of the Black community, specifically Black women. The unique and intersectional position of Black women leaders invites an onslaught of racial challenges in any sector. However, a complex relationship exists between Black women leaders in academia and the metanarratives manufactured by dominant groups. While often viewed as entertainment, the cultural practice of storytelling can incite empowerment and emancipation of the …

Rotenone Induces Regionally Distinct Α-Synuclein Protein Aggregation And Activation Of Glia Prior To Loss Of Dopaminergic Neurons In C57bl/6 Mice, Savannah M Rocha, Collin M Bantle, Tawfik Aboellail, Debotri Chatterjee, Richard Jay Smeyne, Ronald B Tjalkens

Department of Neuroscience Faculty Papers

Rotenone is a naturally occurring insecticide that inhibits mitochondrial complex I and leads to neurochemical and neuropathological deficits closely resembling those in Parkinson's disease (PD). Deficits include loss of dopaminergic neurons (DAn) in the substantia nigra pars compacta (SNpc), decreased dopamine levels and aggregation of misfolded alpha-synuclein (p129). In rat models of rotenone-induced parkinsonism, the progression of neuronal injury has been associated with activation of microglia and astrocytes. However, these neuroinflammatory changes have been challenging to study in mice, in part because the systemic rotenone exposure model utilized in rats is more toxic to mice. To establish a reproducible murine …

Disruption Of Claudin-Made Tight Junction Barriers By Clostridium Perfringens Enterotoxin: Insights From Structural Biology, Chinemerem P. Ogbu, Sourav Roy, Alex J. Vecchio

Department of Biochemistry: Faculty Publications

Claudins are a family of integral membrane proteins that enable epithelial cell/cell interactions by localizing to and driving the formation of tight junctions. Via claudin self-assembly within the membranes of adjoining cells, their extracellular domains interact, forming barriers to the paracellular transport of small molecules and ions. The bacterium Clostridium perfringens causes prevalent gastrointestinal disorders in mammals by employing an enterotoxin (CpE) that targets claudins. CpE binds to claudins at or near tight junctions in the gut and disrupts their barrier function, potentially by disabling their assembly or via cell signaling means—the mechanism(s) remain unclear. CpE ultimately destroys claudin-expressing cells …

Influence Of Fertilizer Rate On Swollen Stem Formation (“Bulbing”) And Vitamin C Content In Different Kohlrabi Cultivars, Mark Iradukunda, Paul E. Read

Honors Program: Senior Projects (Public)

Kohlrabi (Brassica oleracea Gongylodes Group) is a vegetable crop found in the Brassicaceae, and it is rich in antioxidants such as vitamin C. Vitamin C helps in oxidative damage repair and strengthens the immune system, so exploring vitamin C sources may contribute to improving human health. The objective of this study was to determine the effect of different fertilizer rates on kohlrabi yield, in terms of the swollen stem and the vitamin C content, and if those effects are similar in different kohlrabi cultivars. In this greenhouse study, we fertilized four potted kohlrabi cultivars with a common water-soluble greenhouse fertilizer …

Lipid Based Nanoparticles As A Novel Treatment Modality For Hepatocellular Carcinoma: A Comprehensive Review On Targeting And Recent Advances, Khaled Mahmoud, Shady Swidan, Mohamed A. El-Nabarawi, Mahmoud H. Teaima

Pharmacy

Liver cancer is considered one of the deadliest diseases with one of the highest disease burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is considered to be the most common type. Multiple conventional approaches are being used in treating hepatocellular carcinoma. Focusing on drug treatment, regular agents in conventional forms fail to achieve the intended clinical outcomes. In order to improve the treatment outcomes, utilizing nanoparticles—specifically lipid based nanoparticles—are considered to be one of the most promising approaches being set in motion. Multiple forms of lipid based nanoparticles exist including liposomes, solid lipid nanoparticles, nanostructured lipid carriers, …

A Glass Bead Semi‑Hydroponic System For Intact Maize Root Exudate Analysis And Phenotyping, Martha G. Lopez-Guerrero, Peng Wang, Felicia Phares4, Daniel P. Schachtman, Sophie Alvarez, Karin Van Dijk

Department of Biochemistry: Faculty Publications

Background: Although there have been numerous studies describing plant growth systems for root exudate collection, a common limitation is that these systems require disruption of the plant root system to facilitate exudate collection. Here, we present a newly designed semi-hydroponic system that uses glass beads as solid support to simulate soil impedance, which combined with drip irrigation, facilitates growth of healthy maize plants, collection and analysis of root exudates, and phenotyping of the roots with minimal growth disturbance or root damage.

Results: This system was used to collect root exudates from seven maize genotypes using water or 1 mM CaCl …

Expanding Cherenkov Imaging Applications In Radiotherapy: Clinic-Wide In Vivo Treatment Monitoring And Mr-Linac Quality Assurance, Daniel A. Alexander

Dartmouth College Ph.D Dissertations

Radiation therapy treatments have become increasingly complex, striving to improve patient outcomes by delivering sufficient dose for tumor control while sparing more normal tissue. This trend has necessitated the development of additional workflows, such as multilayered incident mitigation strategies and advanced techniques for adapting treatments to account for time-sensitive patient factors. Novel technologies such as optical 3D surface monitoring and magnetic resonance-guided linear accelerators have been developed to assist clinicians in implementing these workflows. We hypothesize that optical imaging methods developed for radiotherapy dose monitoring and measurement can be used to positively impact modern radiation therapy challenges. Cherenkov imaging allows …

Dimensions And Strategies Of Sustainable Rural Entrepreneurship Ecosystem: An Explorative-Mixed Research Study, Mehdi Zivdar, Hadi Sanaeepour

The Qualitative Report

With regards to the concept of sustainability, the dimensions and strategies of the rural entrepreneurship ecosystem have not been identified in most of valid literature of entrepreneurship discipline yet. The aim of this study is to conceptualize dimensions and strategies of Sustainable Rural Entrepreneurship Ecosystem (SREE) phenomenon for clarifying its dimensions and proposing regarding strategies for development of SREE. This study was conducted in two stages using an explorative mixed research design. In the first step, using a qualitative design, SREE was conceptualized, and its dimensions and strategies were developed. Therefore 6 dimensions and 36 strategies were conceptualized based on …

Exploring Ghanaian Adolescent Sexual And Reproductive Health (Srh) Information Source(S): A Qualitative Approach, Daniel Edem Adzovie, Rita Holm Adzovie

The Qualitative Report

Adolescents require information on several issues including sexual and reproductive health (SRH), which most of them receive from numerous sources. The study explored the kinds of SRH information sources adolescents in Ghana are exposed to and the source(s) which serve as their trusted one(s) vis-à-vis reasons given for trusting their sources. Using the Qualitative method of inquiry, the authors employed purposive and snowball sampling techniques to sample and interview twenty-one (n=21) adolescents (female and male) of the university of Cape Coast, Ghana. Results revealed that parents, especially mothers, are the most trusted sources of SRH information to adolescents in Ghana. …

High Potential Antimicrobial Hit-Rate Of A Natural Product Fragment Reassembly Library, Evelyn Schwartz

UM Graduate Student Research Conference (GradCon)

Introduction of new antibiotics into the market is important and urgent. Over the past decade there have been few novel antibiotics and cases of antimicrobial resistance infections is expected to increase. Most antibiotics have been developed with structure-based drug design of known target mechanisms, or from natural products. The limit of using natural products is that many are already diverse and complex in structure and have limited synthetic flexibility. Fragments of natural products are more synthetically pliable and can be linked together similar to amino acids in peptide synthesis. An in-slica library of natural product fragment reassembly (NPFR) would provide …

Sex Determination Of Ritual Violence Victims At Paquimé In Chihuahua, Mexico, Lacy Hazelwood

UM Graduate Student Research Conference (GradCon)

At the prehistoric site of Paquimé in northwestern Chihuahua, Mexico, violence has been linked to the development and maintenance of ritual and social inequality through human sacrifice and performance violence. Across pre-colonial Mexico, human sacrifice coincided with the end or beginning of new seasons, maintenance of hierarchical structures, and offerings to the gods of rain, fertility, and agriculture. Research indicates that preferences for certain demographic variables such as age and sex may have played a significant role in the recruitment of sacrificial victims, and that these were often matched with the deities to whom they were offered. To aid in …

The Forgotten Epidemic: Identification Of Mtbc In The Neolithic Trypillia Of Verteba Cave, Ukraine, Tre Blohm

UM Graduate Student Research Conference (GradCon)

Microorganisms have plagued humankind for millennia and frequently participate in an evolutionary arms race against their hosts. Diseases from various microorganisms have crippled entire countries or led to massive population declines in recent history. However, much is unknown about epidemiology in ancient times. My project will be the first comprehensive paleoepidemiological approach to understand disease across populations in Europe during the Neolithic era (7000-1700BC). The Neolithic was one of the most profound transformations in human history, both culturally and biologically. Massive migrations, formations of the earliest settlements in Europe, and introduction of agriculture and pastoralism led to new environments for …

Assessing The Vulnerability Of At-Risk Amphibians To Regional Climate Change, Ross K. Hinderer

UM Graduate Student Research Conference (GradCon)

Title: Assessing the Vulnerability of At-Risk Amphibians to Regional Climate Change

Purpose: Climate change threatens the persistence of many species worldwide. However, the effects of climate change on a particular species or in a particular location vary based on many factors. Some amphibians may benefit from climate changes while others will not, so understanding the factors associated with higher risks of detrimental effects will allow decision-makers to focus on protecting particularly vulnerable species and populations. Unfortunately, many amphibian species are not well-studied so ecologists are missing key details about their habitat use or life cycle making typical methods …

K-2 Foundational Science, Cassandra Armstrong

Professional Learning Day

During this session, we will explore the progression of science content and skills as presented in the Next Generation Science Standards as they build from Pre-K forward, with a focus on the expectations for K-2 students. By participating in three-dimensional activities, teachers will develop strategies to provide students with opportunities to build a strong foundation in science and STEAM.

Health, Land, And Heritage: Understanding Montana Suicide Through Culture, Emory C. Padgett

UM Graduate Student Research Conference (GradCon)

From Norman Maclean’s A River Runs Through It (1976) to the popular series Yellowstone, stories loom large in Montana, and their use goes beyond entertainment. Stories about the state are informative in understanding Montana culture and heritage because the myths, perspectives, and truths revealed through literature, art, and television are closely intertwined with the memories and values of its people; in an ongoing feedback, stories simultaneously originate in lived experience and actively shape experiences. Grounded in this cultural significance, I use media as an ethnographic lens through which to study social change in rural Montana, which has faced economic …

Predicting Huckleberry Habitat Using Species Distribution Models, Rebekah Brassfield

UM Graduate Student Research Conference (GradCon)

Geographic distribution of plants and animals is determined by a variety of overlapping habitat factors like soil type, elevation, or canopy cover. Understanding the complicated interactions between these factors and the impacts they have on species’ distributions is increasingly important in the face of changing environments and climates. Species distribution models (SDM) measure the importance of habitat variables in determining the spatial distribution of certain species. Because SDMs include a variety of habitat variables, they can be used to answer questions about habitat suitability, predict future distributions, and inform conservation efforts.

Huckleberries (Vaccinium spp.) are a common understory …

Philadelphia Story: Florida Gives William Bartram A Second Chance, Charlotte M. Porter

Florida Historical Quarterly

William Bartram’s book, Travels Through North & South Carolina, Georgia, East & West Florida . . ., published in 1791, presented the most “consistent aesthetic theory produced in America up to his day.“ 1 Two hundred years later, appreciation of this complex work requires an understanding of the author’s intellectual growth, for the Travels is both a volume of natural history and autobiography.

William Bartram's Travels In The Indian Nations, Charlotte M. Porter

Florida Historical Quarterly

In 1773, the famous American naturalist William Bartram returned to the southeast portion of what is now the United States. The region was a more dangerous place than he realized. American “patriots” from Georgia were making troublesome border raids into East Florida. Many of the English plantations were owned in absentia, and the lives of the resident managers were, as Bartram knew from personal experience, isolated. Indian groups far outnumbered white residents in the Floridas, and they were becoming increasingly hostile. With an estimated 4,500 warriors, the Lower Creeks seriously impeded any colonial presence in the East Florida interior. In …

Review Essay: A River Of Peace? The South Florida Frontier In The Nineteenth Century, Gary R. Mormino

Florida Historical Quarterly

Napoleon Bonaparte, a mover and shaper of national boundaries, once insisted that Italy was too long to be a country. Might not reasonable people arrive at the same conclusion about another peninsula, namely, that Florida is too long to be a state?