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2022

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Could Car-T Cell Therapy Be Promising Agent In Acute Lymphoblastic Leukemia?, Omar Khafagy, Shaimaa El-Ashwah, Ashraf Shoma Apr 2022

Could Car-T Cell Therapy Be Promising Agent In Acute Lymphoblastic Leukemia?, Omar Khafagy, Shaimaa El-Ashwah, Ashraf Shoma

Mansoura Medical Journal

CAR T-cell therapy is a recent modality which uses the own T cells of the patient, CAR which represents the genetically engineered and modified fraction of the T cells, includes protein that permit T cells to attack the malignant cells. CAR T can provide long term control of the disease and potential protection against relapse. Chimeric antigen receptor (CAR) T-cell therapy is considered a novel powerful treatment for hematological malignancies. Toxicity still the most common challenge for CAR use. Most common toxicities are cytokine release syndrome and neurologic toxicity. Different factors may influence toxicities as disease burden, conditioning regimens, CAR …

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Immunotherapy Forthyroid Eye Disesase, Aliaa Shohieb, Nashat Shawky, Ashraf Shoma Apr 2022

Immunotherapy Forthyroid Eye Disesase, Aliaa Shohieb, Nashat Shawky, Ashraf Shoma

Mansoura Medical Journal

Thyroid eye disease (TED) is a complex autoimmune disorder that may lead to fundamental morbidity. TED presents with wide range of manifestations originating radically from orbital inflammation which leading to exophthalmos, vision impairment, double vision, severe eye dryness and in advance cases vision loss may occur. On top of that, it has also series of negative impacts on the patient quality of life, psychological and emotional well-being. The full clinical picture of thyroid eye disease (TED) can be explained by the enlargement of the orbit Corticosteroids are the gold stone of treatment in TED. However, in case of steroids withdrawal …

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Pediatric Inflammatory Multisystem Syndrome, Temporally Associated With Sars-Cov-2 (Pims-Ts), Firdaus Hakimi Abdullah, Ashraf Shoma, Ahmed Darwish Apr 2022

Pediatric Inflammatory Multisystem Syndrome, Temporally Associated With Sars-Cov-2 (Pims-Ts), Firdaus Hakimi Abdullah, Ashraf Shoma, Ahmed Darwish

Mansoura Medical Journal

This essay will delve into the knowledge circling the new emerging disease after COVID-19 has spread over the whole world and it affects children for the most part. PIMS-TS symptoms overlapped with Kawasaki Disease (KD) which is hyperinflammatory and multiorgan involvement. PIMS-TS incidence is unknown as of date. Albeit little is known about this disease, reports had shown that this disease is prevalent in the region where KD is not a familiar disease while regions that are famous with KD reported no case of PIMS-TS. While some symptoms overlapped with KD, the difference now is PIMS-TS affect the child of …

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A Phenomenological Study Examining The Experiences Of Single Parents Who Are Rearing Elementary-Aged Children Enrolled In A Public School In A Rural Community, Jenine Lavonne Cotman Apr 2022

A Phenomenological Study Examining The Experiences Of Single Parents Who Are Rearing Elementary-Aged Children Enrolled In A Public School In A Rural Community, Jenine Lavonne Cotman

Doctoral Dissertations and Projects

Abstract The purpose of this qualitative transcendental phenomenological study was to examine the experiences of single parents who are rearing elementary-aged children enrolled in a public school in a rural community. Vygotsky’s sociocultural theory of cognitive development was used to guide this study. Vygotsky’s theory focuses on cognitive development being fundamentally framed by social interaction. Vygotsky also believed that cognitive development is strengthened when a child is encouraged to learn within their zone of proximal development, which refers to a person’s current cognitive space that can be further developed with social interaction and help from a teacher, peer, or parent. …

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Leadership Influence: Adoption Professional, Birth Mother, And Adoptive Parents’ Knowledge Of Open Adoption, Vicki K. Colls Apr 2022

Leadership Influence: Adoption Professional, Birth Mother, And Adoptive Parents’ Knowledge Of Open Adoption, Vicki K. Colls

Doctoral Dissertations and Projects

Adoption needs a minimum of three sets of participants: the birth mother, the adoptive parents, and the adoptive professionals. Being the adoption expert, the adoption professional leads all parties through the process of adoption. However, as adoption research grows, it focuses on the adoptee, birth mother, and adoptive parents but rarely on the adoption professional. As the central figure in the adoption process, the assumption is the adoption professional would be the primary influencer affecting the culture of adoption practices. The purpose of this quantitative descriptive, correlational study was to evaluate if a relationship exists between the adoptive professional's leadership …

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A Phenomenological Study On The Experiences And Needs Of Disabled Students In Higher Education, Alanka Babb Apr 2022

A Phenomenological Study On The Experiences And Needs Of Disabled Students In Higher Education, Alanka Babb

Doctoral Dissertations and Projects

The purpose of this phenomenological study was aimed to describe the experiences of twelve students with disabilities at a higher education institution in Maryland. The theory that guided this study was Luigi Taparelli d’Azeglio’s (1843) and John Rawls’s social justice theory. The social justice theory addresses the importance of equality, access, liberty, and the fair distribution of resources in society to promote social and economic development for all. A qualitative methodology was used to execute the study. Data was collected using focus groups, interviews, and letters. The data was analyzed using Moustaka’s (1994) modification of Van Kaam’s method of phenomenological …

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How Christian Teachers Perceive Their Engagement Facilitates Spiritual Formation Within At-Risk Male Students: A Case Study, Stephanie Eldridge Apr 2022

How Christian Teachers Perceive Their Engagement Facilitates Spiritual Formation Within At-Risk Male Students: A Case Study, Stephanie Eldridge

Doctoral Dissertations and Projects

The purpose of this qualitative intrinsic case study was to understand the experiences of teacher’s perception of their engagement to facilitate spiritual formation within at-risk students at Southeast Christian Alternative School (pseudonym). This participating school is recognized by the North Carolina Department of Administration as a non-public school. The program uses a Wilderness Therapeutic approach to learning. Four essential elements were explored. Teacher’s engagement concerning behavior management was assessed through processes that tactically managed disorderly conduct or acts of misbehavior. Implementation of any behavior plans or behavior models were applicable. Teacher’s engagement concerning spirituality was assessed through active practices of …

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Act Score And Sub Score As Predictors Of Pass/Fail On The Credentialing For Registered Dietitian Nutritionist, Jeanna Marie Haggard Apr 2022

Act Score And Sub Score As Predictors Of Pass/Fail On The Credentialing For Registered Dietitian Nutritionist, Jeanna Marie Haggard

Doctoral Dissertations and Projects

The profession of nutrition and dietetics is currently experiencing a significant change in the educational process with the conversion to a competency based graduate program for the process of licensure and ability to practice in the profession. In addition, the overall pass rate has declined nationwide, thus creating the need for accurate academic predictors for passing. For many health science programs, standardized exams continue to be an effective predictor of passing licensure exams. With many of the institutions of higher education dropping the requirement for test scores as part of the admission process, this is a consideration for many programs …

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Emotional Disconnection Between Parents And Adolescents: Communication Obstacles Among Immigrant Chinese American Christian Families, Agnes Yinshan Man Apr 2022

Emotional Disconnection Between Parents And Adolescents: Communication Obstacles Among Immigrant Chinese American Christian Families, Agnes Yinshan Man

Doctoral Dissertations and Projects

The purpose of this transcendental phenomenological study was to understand and describe the lived experiences of communication that lead to emotional connection issues between Chinese immigrant parents and their American-born adolescent children, particularly in families attending Chinese American Christian churches in Massachusetts. The theory guiding this study was social constructivism, which posits that family members may interpret and experience the same interactions differently from one another. The research questions of the study include: (1) How do first-generation Chinese American Christian parents and second-generation Chinese American Christian adolescent children experience their interaction with each other? (2) How do American-born Chinese Christian …

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Fire Prevention Education For Boys And Girls Who Misuse Fire: A Quasi-Experimental Mixed Methods Analysis Of Effective Intervention Programming, Matthew B. Ferdock Apr 2022

Fire Prevention Education For Boys And Girls Who Misuse Fire: A Quasi-Experimental Mixed Methods Analysis Of Effective Intervention Programming, Matthew B. Ferdock

Doctoral Dissertations and Projects

A child referred for an assessment following fire misuse (e.g., setting a fire intentionally) triggers an intervention strategist who constructs a program that almost universally includes fire safety education (FSE). While FSE media tailored by age and grade is available from the U.S. Federal Government, most youth fire misuse intervention educational programming differentiates children by age. However, program designers rarely consider gender, racial differences, and socioeconomic factors during education design and delivery. Limited research demonstrates efficacious FSE. However, since almost no FSE accounts for differences beyond age, no empirical evidence exists examining its efficacy by demographic or socioeconomic differences. Using …

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Differences Of Attitudes And Norms Toward Plagiarism Between First- And Continuing-Generation College Students, Michael Owen Harris Apr 2022

Differences Of Attitudes And Norms Toward Plagiarism Between First- And Continuing-Generation College Students, Michael Owen Harris

Doctoral Dissertations and Projects

This quantitative, causal-comparative study examines differences in attitudes and subjective norms between first- and continuing-generation college students toward plagiarism. Research studies have reported that up to 90% of college students admitted having committed plagiarism. Plagiarism harms the student who cheats, the reputation of the school, and all associated. First-generation college students experience greater challenges in their first years of college than their continuing-generation peers and may be more at risk for resorting to plagiarism. The researcher employed the Attitude Toward Plagiarism Questionnaire (Cronbach’s score of .79) to measure attitudes and norms toward plagiarism. The findings from the administration form the …

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Childhood Trauma: Nobody Told Me It Would Impact My Marriage Too, Charles Matthew Houston Apr 2022

Childhood Trauma: Nobody Told Me It Would Impact My Marriage Too, Charles Matthew Houston

Doctoral Dissertations and Projects

This thesis project addressed the couple’s ministry life group class at Ridgeville Church of God, as it intends to address how childhood trauma affects married couples. The purpose was to provide proper tools and resources through an education process such as a marriage conference. Chapter One introduces the church’s historical context, mission statement, vision statement, the possible limitations of implementing such a class, and the pastor’s professional background. The literature review in Chapter Two highlights the powerful effects of childhood trauma, especially in individuals’ marriages, more specifically, couples’ intimacy. Survey-style data was the selected method used in this research due …

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Biblical Pastoral Counseling: An Integrative Approach To Healing, Sonya Cook Apr 2022

Biblical Pastoral Counseling: An Integrative Approach To Healing, Sonya Cook

Doctoral Dissertations and Projects

Biblical Pastoral Counseling: An Integrative Approach to Healing, seeks to address the gap in the current biblical counseling service offered at Calvary Baptist Church. The problem with the current biblical counseling service is the lack of a holistic approach to the congregates presenting problem. This current approach takes a strictly biblical approach excluding the mental/behavioral health component from the therapeutic process. The purpose of this study is to provide justification and support of an integrative approach in bridging the gap between biblical counseling and pastoral counseling. This integrative approach would serve to broaden the scope of the current counseling service, …

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Pastoral Counseling Marriage Ministry, Chris Schroeder Apr 2022

Pastoral Counseling Marriage Ministry, Chris Schroeder

Doctoral Dissertations and Projects

Marriage ministry is the topic for this thesis project. Several aspects of marriage ministry at First Baptist Church of Texarkana were evaluated. First, a young single adult group at the church participated in a curriculum for dating before marriage. After being taught the reasons for marriage and dating, the class filled out a survey to evaluate the class’ effectiveness. Next, the pre-marriage counseling at FBC Texarkana was evaluated for effectiveness. Third, crisis marriage counseling at FBC Texarkana was evaluated by the writer to determine if marriages were finding healing. Fourth, a marriage class was offered at FBC Texarkana for a …

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A Phenomenological Study Of The Student Engagement Experiences Of African Americans Formerly Attending Urban Public High Schools, Sohn A. Butts Apr 2022

A Phenomenological Study Of The Student Engagement Experiences Of African Americans Formerly Attending Urban Public High Schools, Sohn A. Butts

Doctoral Dissertations and Projects

The purpose of this hermeneutic phenomenological study was to interpret the student engagement experiences of African Americans formerly attending urban public high schools in a major city in the Mid-Atlantic region of the United States. Self-determination theory, established by Ryan and Deci (1985), is the theoretical framework for this study, and was used to understand motivation in terms of basic psychological needs satisfaction and fulfillment, and how those motivations influence human behavior. The central research question was: What were the student engagement experiences of African Americans formerly attending urban public high schools? The three research sub-questions were: (1) what instructional …

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The Effectiveness Of Attachment Injury Resolution Protocol (Airp) In Reducing Marital Distress And Improving Marital Satisfaction In The Areas Of Communication, Commitment, And Trust In High-Conflict Couples Affected By Infidelity, Sarah R. Cordonnier Apr 2022

The Effectiveness Of Attachment Injury Resolution Protocol (Airp) In Reducing Marital Distress And Improving Marital Satisfaction In The Areas Of Communication, Commitment, And Trust In High-Conflict Couples Affected By Infidelity, Sarah R. Cordonnier

Doctoral Dissertations and Projects

A quasi-experimental pilot study of fourteen heterosexual couples, twenty-eight participants, was conducted to assess whether Attachment Injury Resolution Protocol (AIRP) was effective in reducing marital distress and improving marital satisfaction in the areas of communication, commitment, and trust post infidelity for high-conflict couples. This study was important due to the fact that roughly thirty percent of couples engaged in marital infidelity (Norona et al., 2018). Fourteen heterosexual couples volunteered and were chosen from the clinician’s private mental-health practice to participate in a quasi-experimental pilot study. Four self-report assessments were implemented, including the Kansas Marital Conflict Scale (KMCS), Interpersonal Communication Skills …

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Prevalence And Correlates Of Food And Housing Insecurities At A Historically Black College, Melissa Massey Lockard Apr 2022

Prevalence And Correlates Of Food And Housing Insecurities At A Historically Black College, Melissa Massey Lockard

Doctoral Dissertations and Projects

The purpose of this quantitative, predictive correlational study was to determine the prevalence of food and housing insecurities at one historically Black college and explore whether these insecurities influence students’ academic performance or their mental health quality. The study also explored possible predictors of students at risk of experiencing these basic needs challenges. A convenience sample of 175 participant surveys was collected in the fall 2021 semester at the small, private, liberal arts college in urban South Carolina. The instruments used in the survey included the USDA’s 6-item Household Food Security Survey Module, the Housing Insecurity and Homelessness Module, the …

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Benefits Of Mental Illness Training Programs In The Church, Blessed Onaiwu Apr 2022

Benefits Of Mental Illness Training Programs In The Church, Blessed Onaiwu

Doctoral Dissertations and Projects

The church consists of God’s people. It is the assembly of believers in Jesus Christ. The physical buildings facilitate the fellowship, worship, and ministry of God’s people. According to Matthew 10:8, one of the mandates given to the body of Christ is to heal the sick. Mental illness of any form is an illness that requires proper care and attention. And we know Jesus came to comfort us in all our afflictions which include mental illness; most churches do not address this topic due to stigma. There is often a greater shame regarding this illness within the church than outside, …

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From Mocker To Martyr: The Unlikely Conversion Of James The Brother Of Jesus, Brian Lewis Cunningham Apr 2022

From Mocker To Martyr: The Unlikely Conversion Of James The Brother Of Jesus, Brian Lewis Cunningham

Doctoral Dissertations and Projects

For many years, James, the brother of Jesus, was all but neglected when it came to biblical scholarship. Around four decades ago, there was a resurgence of serious inquiry about James. Since that time, a considerable amount of scholarly material has been published about him, including a possible connection between James and a first-century ossuary box that bears his name. But one aspect of James’s life has not enjoyed such widespread discussion, namely, his conversion. The reason his conversion has been ignored is because there is so little prominent information. The only glimpse afforded to us comes from Jesus appearing …

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Using Spiritual Coping For Compassion Fatigue In Emergency Responders, Elliott Dix Apr 2022

Using Spiritual Coping For Compassion Fatigue In Emergency Responders, Elliott Dix

Doctoral Dissertations and Projects

This thesis project identified areas of improvement concerning compassion fatigue and spiritual coping mechanisms related to emergency responders. This research was unique because it considered how emergency responders served during the Covid-19 pandemic. The research used qualitative methods. Data collection was completed via telephone and in-person interviews. This project may influence others in the field to offer various options, including spiritual measures, when providing coping mechanisms.

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The Decline Of Youth At Ministry Under The Sky, Wanda Elaine Belvin Apr 2022

The Decline Of Youth At Ministry Under The Sky, Wanda Elaine Belvin

Doctoral Dissertations and Projects

The decline of youth attending their services is no secret for many churches. The influences of the world, technology, wanting to fit in are just a few reasons youth find other things to do than attend their church services faithfully. Ministry Under The Sky is a small ministry with a big heart. At its birth in 2001, Ministry Under The Sky’s start was in the researcher’s home and her husband, the Overseer of the ministry. God blessed Ministry Under The Sky with its first building in 2007. The church outgrew the first two buildings less than two years each. The …

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Aging Voices In The American Church Choir: A Study In Ethnomusicology And Ethnodoxology, Shirley Claudeen Ehler Apr 2022

Aging Voices In The American Church Choir: A Study In Ethnomusicology And Ethnodoxology, Shirley Claudeen Ehler

Doctoral Dissertations and Projects

Despite American church choirs being a distinct culture across all denominations and independent church entities, this traditional worship community of singers is a minority culture in the United States. Furthermore, existing journal literature frequently features young voices, e.g., children's, middle school, teen, and university choirs and choruses. Aging-voice research literature began to appear in the 1990s for individual voices or voices in community choirs. Aging voices are a unique ethnicity found in every race within the church choir culture. Researched literature on the aging voice in the American church choir is conspicuous by its absence, pushing American church choir aging …

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Lived Experiences Of Mental Health Professionals Using Resilience To Resist Burnout, Kristen Shawn Cummins Apr 2022

Lived Experiences Of Mental Health Professionals Using Resilience To Resist Burnout, Kristen Shawn Cummins

Doctoral Dissertations and Projects

The purpose of this qualitative transcendental phenomenological study was to describe the lived experiences of mental health professionals (MHPs) in California who have worked in private practice settings. The three research questions that framed this study were: what resilience-promoting mindsets do these mental health professionals rely upon, what resilience-promoting behaviors or practices do they demonstrate, and how do these mindsets and behaviors protect MHPs in private practice from experiencing burnout? The theory guiding this study was the metatheory of resilience and resiliency by Glenn E. Richardson (2002; 2016) as it provided a framework to assess how these professionals utilized resilience …

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Lived Experiences Of Parents And Professionals With Technology And Emotional Dysregulation In Children, Ages 3-5-Years-Old: A Phenomenological Study, Angela P. Rathkamp Apr 2022

Lived Experiences Of Parents And Professionals With Technology And Emotional Dysregulation In Children, Ages 3-5-Years-Old: A Phenomenological Study, Angela P. Rathkamp

Doctoral Dissertations and Projects

Digital devices have become more extensively used and have created a dramatic shift in how children, adolescents, and families use this technology. Excessive screen time has been associated with increased behavioral health problems, sleep disturbances, anxiety, depression, and decreased family functioning. The relationship between problematic technology use and emotional dysregulation in young children is just emerging, therefore leaving a gap in research literature. The purpose of this study was to explore the lived experiences of parents and professionals with technology and emotional dysregulation in children ages 3-5-years-old and to identify emotional characteristics specific to technology and emotional dysregulation. It further …

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An Investigation Of The Impacts Of Locus Of Control On Marital Satisfaction Among Wives Of Combat Veterans With Ptsd In The U.S., Rachel Sims Apr 2022

An Investigation Of The Impacts Of Locus Of Control On Marital Satisfaction Among Wives Of Combat Veterans With Ptsd In The U.S., Rachel Sims

Doctoral Dissertations and Projects

Posttraumatic stress disorder (PTSD) is a significant cause of marital instability and divorce among PTSD veterans, which researchers have cited in the field of psychological disorders. The current study investigated the psychological structure of how marital satisfaction was related to the locus of control among wives of veterans with PTSD diagnosis. No prior studies have explored this relationship, as shown from an extensive search in current literature. The study compared the reported marital satisfaction of women with the locus of control to fill this gap. The family systems theory was applied to guide this research study. In addition, the study …

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God-Image And Romantic Partner Relationships: Emotional Neglect And Adult Women, Danette Alene Buchanan Apr 2022

God-Image And Romantic Partner Relationships: Emotional Neglect And Adult Women, Danette Alene Buchanan

Doctoral Dissertations and Projects

Childhood emotional neglect often leads to relationship dissatisfaction, psychopathology, decline in physical health, and permanent scars from a lack of emotional validation. Women who have grown up with a history of emotional invalidation are at risk for suicide, divorce, emotional instability, unstable relationships, and a chronic belief that they are not enough. Lacking emotional attachment from parents and other primary figures, girls and young women may transition into adulthood either anxiously attached, avoidant attached, or both. This state of dysphoria may extend into their perceptions of God and other authority figures. Counselors and other professional helpers such as clergy, teachers, …

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Examining The Correlation Between Childhood Trauma And Suicidal Ideation Among Air Force Airmen, Jennifer L. Thomas Apr 2022

Examining The Correlation Between Childhood Trauma And Suicidal Ideation Among Air Force Airmen, Jennifer L. Thomas

Doctoral Dissertations and Projects

For decades, the United States military has been concerned about high suicide rates. Due to the increasing suicide rate within the armed forces, the need to better understand suicide-associated factors such as childhood trauma exposure is imperative. It is important to identify the research gaps that exist for promoting understanding of suicide and suicidal behavior and to enhance identification of those at risk for suicide. While there have been many published studies on the topic, conspicuously absent are studies that have included U.S. Air Force personnel. This research will examine the correlation between childhood trauma and suicidal ideation among Air …

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Evangelical Mental Health During A Pandemic: A Three-Way Interaction Analysis, Michael Sean Williams Apr 2022

Evangelical Mental Health During A Pandemic: A Three-Way Interaction Analysis, Michael Sean Williams

Doctoral Dissertations and Projects

COVID-19 quickly became a global pandemic and a biological disaster. Mental health deteriorated due to fear, stress, isolation, and loneliness. Symptoms of anxiety, depression, stress, and disturbed sleep have been associated with COVID-19. There is limited research on mental health and well-being among evangelical Christians. A primary concern is that church congregants and leaders are tired and struggle with mental health issues. Thus, care for the congregation and community is limited. The rate of distress and depression among the religious is on the rise. The purpose of this quantitative research is to evaluate the interaction of perceived stress and emotional …

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Case Study: Exploration Into Principal's Educational Leadership Training And Their Preparation To Lead Special Education Programs In Schools, Tyriq D'Shon Simmons Apr 2022

Case Study: Exploration Into Principal's Educational Leadership Training And Their Preparation To Lead Special Education Programs In Schools, Tyriq D'Shon Simmons

Doctoral Dissertations and Projects

The purpose of this case study was to explore the educational leadership training experiences in special education for school principals of public charter schools in Washington D.C. Guiding this study, is the theory of pedagogical content knowledge (PCK), contributed by Shulman (1986), and the social constructivist theory contributed by Lev Vygotsky (1978). These theories seek to explain the relationship between what principals are expected to know and do based on leadership content knowledge and practical application, specifically in terms of leading special education programs in schools. The central question of this study is: What are the experiences of school principals …

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The Significance Of Trauma In The Relationship Between Co-Occurring Disorders And Recidivism Among Participants Of A Community Mental Health's Jail Diversion Program, Emily A. Schott Apr 2022

The Significance Of Trauma In The Relationship Between Co-Occurring Disorders And Recidivism Among Participants Of A Community Mental Health's Jail Diversion Program, Emily A. Schott

Doctoral Dissertations and Projects

Abstract Individuals with a psychiatric diagnosis have higher levels of criminal justice involvement compared to the general population. Multiple programs have been developed through grant monies utilizing various models to allow these individuals to be linked to mental health services in the community for the treatment of symptoms which may contribute to recidivism. These programs are designed to provide an encounter with mental health professionals who collaborate with law enforcement and other agencies to intercept these individuals at various points of justice involvement and possibly prevent further entanglements with the legal system. This study explores how trauma may impact justice …

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