Digital Commons Network^™

Characterization Of The Responses To Chronic Stress In Caenorhabditis Elegans, Amy Laura Knight

Theses and Dissertations

Exposure to chronic temperature stress influences organismal phenotypes that are important for human health, agriculture, and ecology. In this thesis, the model organism Caenorhabditis elegans was used to study the effects of temperature stress on reproduction and lifespan. It was found that worms demonstrated a rapid shut down in egg-laying between 18-24 hours of exposure to 28°C. Despite this reproductive defect, the overall lifespan of worms was unaffected. At the molecular level, heat shock factor 1 (HSF-1), a regulator of the protective molecular pathway known as the heat shock response (HSR), was identified as important for progeny production during heat …

A Review On Recirculating Aquaculture System: Influence Of Stocking Density On Fish And Crustacean Behavior, Growth Performance, And Immunity, Muziri Mugwanya, Mahmoud A.O. Dawood, Fahad Kimera, Hani Sewilam

Faculty Journal Articles

No abstract provided.

Press Release - 2022-23 June S. Stillman Memorial Endowed Scholarship Winner, University Libraries, Libraries Dean's Advisory Group

Libraries' Documents

Press Release announcing the winner of the 2022-2023 June S. Stillman Memorial Endowed Scholarship, Crystal Lu.

Killing Rarity, Shahrokh Falati

Articles & Chapters

On May 22, 2019, Botswana decided after many years to lift its ban on hunting elephants and in February 2020 held its first auctions for the right to hunt elephants. This turnaround change in their law coincides with a rapidly changing legal landscape in the United States related to the practice of trophy hunting of rare, intelligent animals, including elephants. This Article analyzes the fluid legal landscape surrounding this uncommon form of hunting of rare animals and possible ways of using the Administrative Procedures Act and the Federal Advisory Committee Act as a means of challenging the government’s rapidly changing …

Association Of Underweight And Weight Loss With Poor Prognosis And Poor Therapy Effectiveness In Brain Metastases: A Retrospective Study, Yan He, Yu Zhang, Weelic Chong, Yiyan Pei, Renjie Zhang, Zheran Liu, Jiayi Yu, Xingchen Peng, Fang Fang

Department of Medical Oncology Faculty Papers

Background: The prognostic role of body mass index (BMI) in patients with brain metastases is controversial. We aim to investigate the impact of BMI on prognosis and anti-cancer therapy effectiveness in brain metastases.

Methods: Patients diagnosed with brain metastases between Oct 2010 and July 2019 were followed for mortality through April 2021. The prognostic role of BMI on overall survival was assessed by a restricted cubic spline (RCS) using a flexible model to visualize the relationship between the BMI values and hazard ratios of all-cause mortality, followed by a cox regression model. The disparity of survival outcomes in patients receiving …

Gender-Based Violence In Pakistan And Public Health Measures: A Call To Action, Azza Sarfraz, Zouina Sarfraz, Muzna Sarfraz, Zul Qarnain

Department of Paediatrics and Child Health

No abstract provided.

Expression Of Atwri1 And Atdgat1 During Soybean Embryo Development Influences Oil And Carbohydrate Metabolism, Cintia Lucía Arias, Truyen Quach, Tu Huynh, Hanh Nguyen, Ademar Moretti, Yu Shi, Ming Guo, Amira Rasoul, Kyujung Van, Leah Mchale, Thomas E. Clemente, Ana Paula Alonso, Chi Zhang

Department of Agronomy and Horticulture: Faculty Publications

Soybean oil is one of the most consumed vegetable oils worldwide. Genetic improvement of its concentration in seeds has been historically pursued due to its direct association with its market value. Engineering attempts aiming to increase soybean seed oil presented different degrees of success that varied with the genetic design and the specific variety considered. Understanding the embryo’s responses to the genetic modifications introduced, is a critical step to successful approaches. In this work, the metabolic and transcriptional responses to AtWRI1 and AtDGAT1 expression in soybean seeds were evaluated. AtWRI1 is a master regulator of fatty acid (FA) biosynthesis, and …

Tennessee Farm Bureau News - July 2022, Tennessee Farm Bureau Federation

Tennessee Farm Bureau News

No abstract provided.

Spatial Analysis Of Drug Absorption, Distribution, Metabolism, And Toxicology Using Mass Spectrometry Imaging, Michelle L Spruill, Mirjana Maletic-Savatic, Howard Martin, Feng Li, Xinli Liu

Faculty, Staff and Students Publications

Mass spectrometry imaging (MSI) is emerging as a powerful analytical tool for detection, quantification, and simultaneous spatial molecular imaging of endogenous and exogenous molecules via in situ mass spectrometry analysis of thin tissue sections without the requirement of chemical labeling. The MSI generates chemically specific and spatially resolved ion distribution information for administered drugs and metabolites, which allows numerous applications for studies involving various stages of drug absorption, distribution, metabolism, excretion, and toxicity (ADMET). MSI-based pharmacokinetic imaging analysis provides a histological context and cellular environment regarding dynamic drug distribution and metabolism processes, and facilitates the understanding of the spatial pharmacokinetics …

What Are Mycorrhizal Traits?, V. Bala Chaudhary, E. Penelope Holland, Suw Charman-Anderson, Aidee Guzman, Lukas Bell-Dereske, Tanya E. Cheeke, Adriana Corrales, Jessica Duchicela, Cameron Egan, Pushpa G. Soti

School of Integrative Biological & Chemical Sciences (Formerly Dept. of Biology)

Highlights

• Applying trait-based approaches to ecological research on mycorrhizal symbioses broadens ecological inferences, but there is no single unified framework to unite disparate language, terminology, and methods across the many multidisciplinary scientists studying mycorrhizas.
• We propose an inclusive framework for trait-based mycorrhizal ecology aimed to stimulate scientists around the world to collect and use more mycorrhizal trait data, particularly in understudied areas. This would widen our understanding regarding the ecological role of mycorrhizal symbioses at individual, species, community, and ecosystem scales.
• Analyzing how mycorrhizal symbioses fit within existing trait definitions highlights significant theoretical and empirical knowledge gaps, novel questions, and …

Building Services Engineering July/August 2022

Building Services Engineering

No abstract provided.

Characterization And Assessment Of Barriers And Facilitators To The Decision-Making Process For Blood And Blood Donor Safety In The United States: A Collective Case Study, Lauren A. Crowder

Doctor of Philosophy in Translational Health Sciences Dissertations

Background: Over 16 million blood components are transfused to patients in need every year in the United States (Jones et al., 2021). Because of the reliance on human blood donors, the donation and transfusion of blood will always be associated with some level of risk for both donors and recipients; the tolerability of these risks may vary from stakeholder to stakeholder. While the U.S. Food and Drug Administration (FDA) concedes that attaining a blood supply with zero risk for transmission of infectious diseases may be unattainable (U.S. Food and Drug Administration, 2019), they continue to strive for the lowest …

Non-Gaussian Analysis Of Herbarium Specimen Damageto Optimize Specimen Collection Management, Aris Yaman, Yulia Aris Kartika, Ariani Indrawati, Zaenal Akbar, Lindung P. Manik, Wita Wardani, Tutie Djarwaningsih, Taufik Mahendra, Dadan R. Saleh

Knowledge Engineering and Data Science

Damage to specimen collections occurs in practically every herbarium across the world. Hence, some precautions must be taken, such as investigating the factors that cause specimen damage in their collections and evaluating their herbarium collection handling and usage policy. However, manual investigation of the causes of herbarium collection damage requires a lot of effort and time. Only a few studies have attempted to investigate the causes of herbarium collection damage. So far, the non-gaussian approach to detecting the causes of damage to herbarium specimens has not been studied before. This study attempted to explore the effect of species type, time, …

How And Why Do Judges Cite Academics? Evidence From The Singapore High Court, Jerrold Soh, Yihan Goh

Research Collection Yong Pung How School Of Law

Legal academics were once thought to be parasitic on the work of judges, so much so that citing academic work was said to weaken a judgment’s authority. Recent times have however seen prominent academics appointed to the highest courts, and judicial engagement with academic materials appears to have increased. In this light, this article empirically studies academic citation practices in the Singapore High Court. Using a dataset of 2,772 High Court judgments, we show that citation counts have indeed increased over time, even in this first-instance court. This increase was distributed across most legal areas, and was not limited to, …

Reduced Chest Computed Tomography Scan Length For Patients Positive For Coronavirus Disease 2019: Dose Reduction And Impact On Diagnostic Utility, Sara Principi, Stacy D. O'Connor, Frank Luba, Taly Gilat Schmidt

Biomedical Engineering Faculty Research and Publications

Objective

This work aimed to retrospectively evaluate the potential of dose reduction on chest computed tomography (CT) examinations by reducing the longitudinal scan length for patients positive for coronavirus disease 2019 (COVID-19).

Methods

This study used the Personalized Rapid Estimation of Dose in CT (PREDICT) tool to estimate patient-specific organ doses from CT image data. The PREDICT is a research tool that combines a linear Boltzmann transport equation solver for radiation dose map generation with deep learning algorithms for organ contouring. Computed tomography images from 74 subjects in the Medical Imaging Data Resource Center–RSNA International COVID-19 Open Radiology Database data …

Onasemnogene Abeparvovec For Presymptomatic Infants With Two Copies Of Smn2 At Risk For Spinal Muscular Atrophy Type 1: The Phase Iii Spr1nt Trial, Kevin A Strauss, Craig M Zaidman, Et Al

2020-Current year OA Pubs

SPR1NT ( NCT03505099 ) was a Phase III, multicenter, single-arm study to investigate the efficacy and safety of onasemnogene abeparvovec for presymptomatic children with biallelic SMN1 mutations treated at ≤6 weeks of life. Here, we report final results for 14 children with two copies of SMN2, expected to develop spinal muscular atrophy (SMA) type 1. Efficacy was compared with a matched Pediatric Neuromuscular Clinical Research natural-history cohort (n = 23). All 14 enrolled infants sat independently for ≥30 seconds at any visit ≤18 months (Bayley-III item #26; P < 0.001; 11 within the normal developmental window). All survived without permanent ventilation at 14 months as per protocol; 13 maintained body weight (≥3rd WHO percentile) through 18 months. No child used nutritional or respiratory support. No serious adverse events were considered related to treatment by the investigator. Onasemnogene abeparvovec was effective and well-tolerated for children expected to develop SMA type 1, highlighting the urgency for universal newborn screening.

Financial Aid, Saint Mary's College Of California

Academic Catalog

No abstract provided.

Core-Designated Courses, Saint Mary's College Of California

Academic Catalog

No abstract provided.

2022-2023 Academic Catalog, Saint Mary's College Of California

Academic Catalog

No abstract provided.

Course Descriptions, Saint Mary's College Of California

Academic Catalog

No abstract provided.

Majors And Minors, Saint Mary's College Of California

Academic Catalog

No abstract provided.

Student Life, Saint Mary's College Of California

Academic Catalog

No abstract provided.

Interdiscipliarity Evolution Of Disciplines: A Perspective Of Nsfc, Xiaolan Wu, Chengzhi Zhang

Journal of Scientific Information Research

[Purpose/significance]With the development of science and technology,disciplines crossing and permeating is increasing.Therefore,it is of great significance for the development of interdisciplinary research and science and technology planning to explore the evolution trend of interdisciplinary research.[Method/process]Based on the output of NSFC papers and the hierarchical classification of NSFC projects from 2008 to 2016,this paper analyzes the interdisciplinary evolution trend of the disciplines of VIP journals by using Brillouin index and three-dimensional indexes of balance,disparity and variety.[Result/conclusion]The research shows that the interdisciplinary of all disciplines is rising steadily in 2008-2016.In addition, the balance of most disciplines is declining,the disparity and variety of …

Correlation Between Body Mass Index And Serum Calcium Levels In Adults Sudanese People, Gezira State: Correlation Between Body Mass Index And Serum Calcium Levels In Adults Sudanese People, Gezira State, Nesreen Alrayah, Ahmed Mak, Osman Saeed, Gadallah Modawe

Iraqi National Journal of Medicine

Background; Calcium is necessary nutrient for normal growth and development. The study aimed to document the normal values of serum calcium levels in healthy Sudanese adults in gezira state and its relation to the body mass index (BMI). Patients and Methods: A cross-sectional study was conducted during 2018 to 2021 in Gezira state on 534 adults,42.3% (226) were males and 57.7% (308) were females, age ranged from 20 and 60 years. A questionnaire was used for data collection to assess the essential demographic data. Three ml of blood was collected in heparin vacuum tubes and serum calcium was measured by …

Odontometric Sex Estimation Using A Modern Forensic Skeletal Collection, Andrea Sbei

Department of Anthropology: Theses and Student Research

Forensic anthropologists are responsible for estimating the biological profile—the age, sex, population affinity, and stature—of unknown deceased individuals. Many methods used for estimating the biological profile are sex-specific, which implicates sex estimation as one of the most important components of the biological profile. Historically, the skull and postcranial elements have been heavily utilized for morphological and metric sex estimation methods, whereas odontometric methods have been overlooked and underutilized. Odontometric data has proven to be a worthwhile avenue for the estimation of sex in several population-based studies (Acharya et al., 2011; Adams & Pilloud, 2019; Angadi et al., 2013; Cardoso, 2008; …

One Space Can Put Her In A Different Place - How Do We Inhabit Spaces Differently?, Farida Youssef

Theses and Dissertations

In Egypt, a male-dominated society, women are forced to constantly negotiate with patriarchal systems. Dichotomies and paradoxes between principles governing different gendered roles, religion and cultural codes and westernization and commercialization have been continuously shaping Egyptian women’s status over the past decades. This is exhibited in public spaces, where women’s current preferences, perceptions and behavior emphasize the dominance of one gender over the other. This research aims for a better understanding of space inhabitance through a gendered lens. It questions the roles the society and the urban spaces play in the daily lives of women through examining women’s perception of …

Self-Supervised Video Representation Learning By Uncovering Spatio-Temporal Statistics, Jiangliu Wang, Jianbo Jiao, Linchao Bao, Shengfeng He, Wei Liu, Yun-Hui Liu

Research Collection School Of Computing and Information Systems

This paper proposes a novel pretext task to address the self-supervised video representation learning problem. Specifically, given an unlabeled video clip, we compute a series of spatio-temporal statistical summaries, such as the spatial location and dominant direction of the largest motion, the spatial location and dominant color of the largest color diversity along the temporal axis, etc. Then a neural network is built and trained to yield the statistical summaries given the video frames as inputs. In order to alleviate the learning difficulty, we employ several spatial partitioning patterns to encode rough spatial locations instead of exact spatial Cartesian coordinates. …

Designing Flipped Learning Activities For Beginner Programming Course, Benjamin Gan, Eng Lieh Ouh

Research Collection School Of Computing and Information Systems

This study focuses on designing flipped classroom learning activities across pre-class problem-based exercises; with in-class active discussions and practical problem-solving sessions; and follow up with postclass problem-based labs and assessments. We evaluate the effectiveness of our learning activities based on student surveys, course feedback, grades, and teacher feedback for a beginner programming course with non-IS students. We describe detail programming learning activities with comparisons to existing practices based on related work. Our findings are that majority of students (86%) agreed with flipped classroom, but teachers should be aware of the 14% who disagreed and cater for them. Teachers should avoid …

Docee: A Large-Scale And Fine-Grained Benchmark For Document-Level Event Extraction, Meihan Tong, Bin Xu, Shuai Wang, Meihuan Han, Yixin Cao, Jiangqi Zhu, Siyu Chen, Lei Hou, Juanzi Li

Research Collection School Of Computing and Information Systems

Event extraction aims to identify an event and then extract the arguments participating in the event. Despite the great success in sentencelevel event extraction, events are more naturally presented in the form of documents, with event arguments scattered in multiple sentences. However, a major barrier to promote documentlevel event extraction has been the lack of large-scale and practical training and evaluation datasets. In this paper, we present DocEE, a new document-level event extraction dataset including 27,000+ events, 180,000+ arguments. We highlight three features: largescale manual annotations, fine-grained argument types and application-oriented settings. Experiments show that there is still a big …

Unm Pathology Pathfinder Summer 2022, Unm Department Of Pathology

Newsletters

No abstract provided.