Digital Commons Network^™

Pd-1/Pd-L1 Pathway: A Therapeutic Target In Cd30+ Large Cell Lymphomas, Wei Xie, L Jeffrey Medeiros, Shaoying Li, Guilin Tang, Guang Fan, Jie Xu

Faculty, Staff and Student Publications

The programmed death-ligands, PD-L1 and PD-L2, reside on tumor cells and can bind with programmed death-1 protein (PD-1) on T-cells, resulting in tumor immune escape. PD-1 ligands are highly expressed in some CD30+ large cell lymphomas, including classic Hodgkin lymphoma (CHL), primary mediastinal large B-cell lymphoma (PMBL), Epstein-Barr virus (EBV)-positive diffuse large B-cell lymphoma (EBV+ DLBCL), and anaplastic large cell lymphoma (ALCL). The genetic alteration of the chromosome 9p24.1 locus, the location of

Predicting The Topographic Zonation Of Vegetation In A Salt Playa In Utah, Usa, Roger T. Koide, Jakob Garlick, Spencer Klatt, Noah Boekweg, Augustine Tambe, Katherine Jensen, Emily Weatherhead

Western North American Naturalist

Vegetation in salt playas—iconic landforms in the Great Basin of the western United States—exhibits a striking topographical zonation that has remained unexplained. In particular, a distinctive pattern is exhibited by salt-succulent species in the Amaranthaceae wherein Allenrolfea occidentalis occurs in monospecific stands at the highest topographic position in the playa, Sarcocornia utahensis occurs in monospecific stands in the middle position, and Salicornia rubra occurs in monospecific stands at the lowest topographic position. Because salt playas feature a shallow, temporary winter lake that recedes as it evaporates throughout the summer and because vegetation zones closely follow the contours of the temporary …

Aroma And Baking Characteristics Of Kiwifruit And Its Bread Fermented By Pediococcus Pentosaceus, Huang Jing, Iang Li-Ting, Chen Cheng, Guo Rui-Jun, Huang Wei-Ning, Zeng Yong-Qing, Li Ning, Gao Tie-Cheng, Zhou Li-Yuan

Food and Machinery

Objective:This study aimed to explore the effect of Pediococcus pentosaceus J8 fermented kiwifruit on bread baking and flavor profile characteristics of wheat bread. Methods: The changes in β glucosidase enzyme activity, organic acids and flavor compounds during kiwifruit fermentation were analyzed. The physical and chemical properties of wheat dough incorporated with fermented kiwifruit were determined. Moreover, the changes in total dietary fiber and total amino acid content, bread quality and flavor characteristics of the resulted bread were also determined. Results: After 15.5 hours of fermentation, the β glucosidase activity reached 55.13 U/L, and the content of lactic acid and …

Comparison Of Active Components And Antioxidant Activity Of Non-Medicinal Parts Of Polygonatum Cyrtonema, Wang Tian-Mei, Wang Hua-Lei, Li Dan-Dan, Chen Song-Shu, Pan Ke-Qin

Food and Machinery

Objective:This study focuses on improving the comprehensive utilization rate of Polygonatum cyrtonema.Methods:The contents of total flavonoids, total saponins and total phenols from roots, stems, leaves, flowers and buds, of P. cyrtonema were determined. The scavenging rates of DPPH·, ·OH and nitrites in extracts of above tissue were measured and compared as well. Results:The contents of total flavonoids and total phenols five different kinds of non-medicinal tissue were in the same order, in which from highest to lowest was, leaves, buds, flowers, stems and roots, and the content of total saponins in flower was the highest In terms of …

Detection Device For Microfluidic Molds Airborne In Food (Beverage) Processing Workshop, Zhao Zhong-Ying, Xu Pei-Feng, Yan Fang

Food and Machinery

Objective:To monitor and control mold spores contamination effectively in food (beverage) processing workshops.Methods:The mold spores are enriched and classified by microfluidic chip, and the air aerosol was collected in 2~10 micron channel and prepared on film. Finally, spore images were taken by camera and electron microscope, and spores were detected, distinguished and counted by Canny algorithm.Results:Compared with the traditional falling plate method, the detection device designed in this paper could detect 103cell/mL mold spores sprayed in the air within 20 minutes.Conclusion:Using airborne UAV to detect mold pollution in food (beverage) processing workshop in the air …

Effects Of Heat Pump Drying Temperature On Drying Characteristics And Quality Of Persimmon Slices, Tang Xiao-Xian, Zheng Jing, Ren Ai-Qing, Duan Zhen-Hua, Wei Zhen-Zhen, Qin Yan-Ting, Fu Hai-Ping

Food and Machinery

Objective:In order to explore the effect of heat pump drying temperature on the drying characteristics and quality of persimmon slices;Methods:Taking persimmon as the raw material, the effects of different drying temperatures were compared, on the drying time, drying rate, color, hardness, rehydration rate, tannin content, total sugar, vitamin C and total acid content of dried persimmon slices.Results:when the heat pump drying temperature was 65 ℃, the drying rate was higher and the drying time was shorter. The dried persimmon slices dried at 65 ℃ had bright color, similar to fresh fruit color, good rehydration performance, the lowest …

Purification Processing Of Pigment From Boletus Eduliswith Macroporous Resin And Its Antioxidant Capacity, Guo Lei, Zi Lu-Xi, Cui Qi, Zhou Yu, Qiu Hui-Ting, Kan Huan

Food and Machinery

Objective:The aim of this work is to obtain the optimal purification process of pigment from Boletus edulis by macroporous resin, and study its antioxidant activity. Methods:Based on the static and dynamic test, the influence of resin type, sample concentration, pH, loading flow ratio, ethanol concentration and elution flow ratio on the adsorption and desorption activity of Boletus edulis pigment were investigated to determine the optimal purification conditions. Then the structure, the DPPH·, ABTS+· and ·OH scavenging activity of the Boletus edulis pigment purified was also evaluated. Results:AB-8 was the most suitable type of macroporous resin and the optimum …

Auxiliary Hypoglycemic Effect Of Compound Nutritional Powder On Stz Rats, Sheng Qing-Hai, Liu Cheng, Pan Li-Na, Wang Jia-Qi, Jia Yan-Ju

Food and Machinery

Objective:This study focuses on evaluating the auxiliary blood glucose-lowering function of self-made compound nutritional powder in type 2 diabetic rats.Methods:SD rats were intravenously injected with STZ to construct a pancreatic islet injury type 2 diabetes model. The compound nutritional powder was given by oral gavage at doses of 1.68, 3.35 and 6.70 g/kg for 30 days. Fasting blood glucose and blood glucose were measured after 30 days. Glucose tolerance index to investigate the effect of compound nutrients on STZ rats.Results:The compound nutritional powder was positive for the fasting blood glucose and glucose tolerance indexes of STZ rats; …

Study On The Effect Of Chrysanthemum Polysaccharide On Hypoglycemic In Type 2 Diabetic Rats, Zhao Kai-Di, Wang Qiu-Dan, Lin Chang-Qing

Food and Machinery

Objective:This study aimed to investigate the hypoglycemic effect of chrysanthemum polysaccharide on type 2 diabetes (T2DM) rats.Methods:The chrysanthemum polysaccharides were extracted by water extraction and alcohol precipitation. After feeding rats with high-fat and high-sugar feed for 6 weeks, STZ (30 mg/kg·BW) was injected intraperitoneally to establish a T2DM rat model, and records were recorded during the experiment. Rat body weight, food intake, water consumption, fasting blood glucose (FBG) was measured every two weeks, and glucose tolerance (OGTT) test was performed in the last week of the test; the insulin (INS) level was measured by Elisa method, and insulin resistance …

Dcs At The Center Of Help: Origins And Evolution Of The Three-Cell-Type Hypothesis, Renee Wu, Kenneth M Murphy

2020-Current year OA Pubs

Last year was the 10th anniversary of Ralph Steinman's Nobel Prize awarded for his discovery of dendritic cells (DCs), while next year brings the 50th anniversary of that discovery. Current models of anti-viral and anti-tumor immunity rest solidly on Steinman's discovery of DCs, but also rely on two seemingly unrelated phenomena, also reported in the mid-1970s: the discoveries of "help" for cytolytic T cell responses by Cantor and Boyse in 1974 and "cross-priming" by Bevan in 1976. Decades of subsequent work, controversy, and conceptual changes have gradually merged these three discoveries into current models of cell-mediated immunity against viruses and …

Sentience In Decapods: An Open Question, Mark Briffa

School of Biological and Marine Sciences

No abstract provided.

Activation Of Autophagic Flux Maintains Mitochondrial Homeostasis During Cardiac Ischemia/Reperfusion Injury, Lihao He, Sumanth D Prabhu, Et Al

2020-Current year OA Pubs

Reperfusion injury after extended ischemia accounts for approximately 50% of myocardial infarct size, and there is no standard therapy. HDAC inhibition reduces infarct size and enhances cardiomyocyte autophagy and PGC1α-mediated mitochondrial biogenesis when administered at the time of reperfusion. Furthermore, a specific autophagy-inducing peptide, Tat-Beclin 1 (TB), reduces infarct size when administered at the time of reperfusion. However, since SAHA affects multiple pathways in addition to inducing autophagy, whether autophagic flux induced by TB maintains mitochondrial homeostasis during ischemia/reperfusion (I/R) injury is unknown. We tested whether the augmentation of autophagic flux by TB has cardioprotection by preserving mitochondrial homeostasis both …

Building Bridges Between Natural And Social Science Disciplines: A Standardized Methodology To Combine Data On Ecosystem Quality Trends, I. Richter, B. R. Roberts, S. F. Sailley, E. Sullivan, V. V. Cheung, J. Eales, M. Fortnam, J. B. Jontila, C. Maharja, T. Ha Nguyen, S. Pahl, R. A. Praptiwi, J. Sugardjito, J. D.C. Sumeldan, W. M. Syazwan, A. Y. Then, M. C. Austen

School of Psychology

Despite a growing interest in interdisciplinary research, systematic ways of how to integrate data from different disciplines are still scarce. We argue that successful resource management relies on two key data sources: natural science data, which represents ecosystem structure and processes, and social science data, which describes people's perceptions and understanding. Both are vital, mutually complementing information sources that can underpin the development of feasible and effective policies and management interventions. To harvest the added value of combined knowledge, a uniform scaling system is needed. In this paper, we propose a standardized methodology to connect and explore different types of …

Predicting Suicide In Counties: Creating A Quantitative Measure Of Suicide Risk, Kate Mobley, Gita Taasoobshirazi

Faculty Articles

Rising rates of suicide over the past two decades have increased the need for wide-ranging suicide prevention efforts. One approach is to target high-risk groups, which requires the identification of the characteristics of these population sub-groups. This suicidology study was conducted using large-scale, secondary data to answer the question: using the research on suicide, are there variables studied at the community level that are linked to suicide and are measurable using quantitative, demographic data that are already collected and updated? Data on deaths from suicide in U.S. counties for the years 2000, 2005, 2010 and 2015 were analyzed using multiple …

Using Data Mining Techniques To Improving Key Performance Indicators, Assem Khalaf Ahmed [email protected], [email protected]

Future Computing and Informatics Journal

The study provides a framework for improving the most key performance indicators and arranging them according to the degree of impact in order to enhance decision-making, speed and increase accuracy in data analysis, reduce mismanagement and time to take appropriate decisions a timely manner and ensure that the organization is moving towards achieving its goals, through one of the techniques of business intelligence (Data Mining and Knowledge discovery) and choosing the best technique that can be used to improve the key performance indicators.

Breeding Ecology Of Mottled Ducks In Southwestern Louisiana, Elizabeth Sophia Bonczek

LSU Doctoral Dissertations

Mottled ducks are a resident species found in the southern United States that rely on coastal marsh and associated habitat to fulfill the needs of the entirety of their annual cycle. Population monitoring has revealed declines in western Gulf Coast (WGC) mottled ducks since 2008. Mottled duck populations are influenced by survival and recruitment, and changes in these factors may contribute to population declines. The overarching goal of this project was to identify the mechanisms potentially limiting WGC mottled ducks.

I captured adult female mottled ducks during molt on Rockefeller Wildlife Refuge and adjacent lands in southwestern Louisiana from 2017–2019. …

Chloride Channels That Mediate A Transient Nitric Oxide-Dependent Synaptic Polarity Switch In Retinal Amacrine Cells., Tyler Christopher Rodriguez

LSU Doctoral Dissertations

Cytosolic chloride (Cl^-) concentration determines whether GABAergic and glycinergic synapses are inhibitory or excitatory. Ionotropic GABA and glycine receptors passively conduct Cl­^- leading to membrane depolarization or hyperpolarization depending on the Cl^- equilibrium potential. Accordingly, the distribution of Cl^- across the plasma membrane has the potential to determine the properties of networks of retinal amacrine cells (ACs) and their postsynaptic partners. Ion channels are responsible for establishing Cl^- reversal potential. Nitric oxide (NO) is a signaling molecule that can be generated in the inner retina where ACs form synapses. We have shown that NO …

Shared Voices Of Indonesian Teacher-Educators From Virtual Research-Workshop-Series: Reflections On Covid-19 Pandemic Driven Professional Development, Dyah Sunggingwati, Sudarman Sudarman, Abdul Hakim, Haviluddin Haviluddin

The Qualitative Report

This study aims to explore the perceptions and experiences of Teacher-Educators (TEs) who participated in virtual research-workshop-series as professional development programs. Six TEs, three from natural science and three from social science, participated in a nine-month virtual research workshop series organized by the faculty. In the frame of a case study, the data were gathered from in-depth interviews and a set of questions. The findings revealed that TEs had sufficient research knowledge as they were able to identify good quality of research, read relevant reading research, and signified the importance of research as part of their professional identity. Completion of …

The Adaptation Of Export-Scale Urban Farmers Amid The Covid-19 Pandemic In Bandung Metropolitan, Kinanti Indah Safitri, Oekan Soekotjo Abdoellah, Budhi Gunawan, Parikesit -, Yusep Suparman, Akhmad Zainal Mubarak, Margareth Pardede

The Qualitative Report

These days, urban agriculture is more than a hobby. It has expanded into a local commercial business, even to an export scale. However, urban farmers who have commercialized their products must adapt to the COVID-19 pandemic situation, which has impacted many aspects of global life. This research used a mixed-method approach. We collected quantitative data from 107 respondents on the household commercialization index, income level, and education level of export-scale-urban farmers in the Bandung metropolitan area, West Java, Indonesia. We also used qualitative data to determine how farmers were adapting to difficult situations due to the COVID-19 pandemic. This information …

The Role Of Protein Palmitoylation In Two Disorders; X-Linked Intellectual Disability And Covid-19, Ahmed A. Ramadan

USF Tampa Graduate Theses and Dissertations

The spike proteins of enveloped viruses are transmembrane glycoproteins that typically undergo post-translational attachment of palmitate on cysteine residues on the cytoplasmic facing tail of the protein. The role of spike protein palmitoylation in virus biogenesis and infectivity is being actively studied as a potential target of novel antivirals. Here, we report that palmitoylation of the first five cysteine residues of the C-terminal cysteine-rich domain of the SARS-CoV-2 S protein are indispensable for infection, and palmitoylation-deficient spike mutants are defective in membrane fusion. The DHHC9 palmitoyltransferase interacts with and palmitoylates the spike protein in the ER and Golgi, and knockdown …

Plastic And Evolved Responses In The Eastern Oyster, Crassostrea Virginica, To Environmental Variation In The Northern Gulf Of Mexico, Kyle Sirovy

LSU Doctoral Dissertations

Climate change and other anthropogenic impacts are causing rapid alterations to many of the world’s most productive coastal ecosystems and there is an urgent need to understand how species will respond to these environmental changes. Organisms may respond through plasticity, evolution, or the evolution of plasticity. In this dissertation, I evaluate the role of plastic and evolved responses in the eastern oyster, Crassostrea virginica, to environmental variation in the northern Gulf of Mexico. I use comparative transcriptomics, physiology, and morphology to examine the relative contribution of plastic and evolved responses for oysters exposed to low salinity and outplant sites …

Review Of Emerging Approaches Utilizing Alternative Physiological Human Body Fluids In Non- Or Minimally Invasive Glucose Monitoring, Sunghoon Jang, Yu Wang, Andre Jang

Publications and Research

Diabetes can cause various acute as well as long-term complications in patients, with blood sugar levels of over 600 mg/dL, such as blindness, kidney disease, nervous & circulatory system disease, limb amputations, stroke, and cardiovascular disease (CVD). Frequent and regular blood glucose monitoring by diabetics and physicians is an essential step in the management of diabetes. Over the last five decades, there have been numerous attempts to develop viable painless non- or minimally invasive blood glucose monitoring techniques to replace all existing invasive methods, such as home blood glucose monitoring, which usually require drawing a blood sample by piercing the …

Exploring The Potential Of Halal Tourism Through Institutional Analysis Of Halal Certifiers In The Philippines, Steven Von Cuevas, Cristopher Allen Franco, Robert Charles Capistrano, Junnell Guia

International Journal of Religious Tourism and Pilgrimage

This study analyses various institutions’ halal certification and standards in the Philippines and their potential for halal tourism. The demand for halal services and products has been increasing in the Philippines, however, the major halal certifiers in the country uphold different standards, leading to confusion and abuse in halal accreditation and certification. The unification of halal standards is a complex process due to varying interpretations and thus, this research utilised case study methods to analyse the similarities and differences of the three major halal certifiers in the country within the lenses of the Work System Elements Framework and the Institutional …

Florida Historical Quarterly, Volume 96, Number 3, Florida Historical Society

Florida Historical Quarterly

No abstract provided.

La Florida In The Creole Imaginary: The Frontier Of New Spain In Francisco De Florencia's Historia De La Provincia (1694), Jason Dyck

Florida Historical Quarterly

"Are our oldest heroes only to be found in the colonial history of the "Thirteen Original States?""1 Jose Manuel Espinosa posed this question in 1935 in a brief article on the Jesuit Francisco de Florencia (1620-1695), one of the most prolific sacred historians of Spanish America. As a student of Herbert E. Bolton-a pioneering historian of the borderlands-Espinosa argued that Florida should be considered part of the colonial history of the United States even if it was mostly under Spanish rule until 1821.2 Since Florencia was born in Saint Augustine, Espinosa debunked what he called the "Brooke legend," the belief …

Title Page, Florida Historical Society

Florida Historical Quarterly

Title page for Volume 96, Number 4. Includes the Table of Contents

Why Africa? Towards A Materialist Understanding Of Racism And The African Slave Trade, Giacomo F. Green

Swarthmore Undergraduate History Journal

Common historical interpretations of the Atlantic slave system often lose the position Africa within the political-economic haze of the era, either producing confused accounts or eliding the question of causality altogether. I argue that this tendency stems from the corrosive effects of the historian’s position as an observer from the present, and that to understand why Africa was the prime location for the source of human slaves, one needs to take a materialist approach to the problem of origins. Only through careful examination of empire, the plantation complex, and the genesis of the Atlantic working classes can one arrive at …

Medicinal Plants And Herbs For Cancer Prevention, Madeline Mctigue, Julianna Goelzer, William Ranahan

Research Symposium

Modern medicine has yet to produce selective treatments for the vast majority of cancer types. Most chemotherapies, though complex, remain non-specific, and thus destroy healthy cells. Over 25% of cancer patients die from the effects of chemotherapy before the actual tumor would have progressed to the point of organismal death (Megget 2008). Early detection remains the most accurate indicator of successful treatment outcome. But why wait until the disease presents to deal with it? Here the authors argue that a well supported immune system coupled with a dietary regimen of key food-based medicines is a far superior strategy. Given that …

Eeg Neurofeedback And Isolation Stressor. A Systematic Review, Kacper Gotner, Marcin Dornowski

Baltic Journal of Health and Physical Activity

Introduction. One of the factors increasing the body's response to a stressful situation is isolation. The feeling of loneliness in isolation can be caused by biological, psychological or medical factors. Material and methods: This paper is a review of publications issued in 2009–2021, the most up-to-date in terms of information on the topic of stress and its links with EEG neurofeedback. Results: 5 publications on stress caused by isolation and the reaction of the human body in a stressful situation were selected. The papers were selected based on the use of EEG neurofeedback in reducing the body's stress reactions to …

Gendered Political Violence As A Legal Framework: An Analysis Of The Brazilian Reality, Adriana Jacob Carneiro, Farida Jalalzai, Pedro A. G. Dos Santos

Political Science Faculty Publications

In August of 2021, the Brazilian government sanctioned in the Electoral Code and the Penal Code the typification of violence against women in politics (VAWIP) as a punishable crime. This research provides a critical analysis of the implementation of the 2021 Law n. 14.192 that typifies VAWIP as a crime. To do so we discuss how the law addresses, in theory, the types of VAWIP identified in the extant literature (physical, psychological, sexual, economic, and semiotic). We then discuss Brazil’s VAWIP law contextualizing it within the Brazilian political landscape, regional (as well as global) perspectives on the issue, and comparing …