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Structure-Property Investigations In Urea Tethered Iodinated Triphenylamines, Muhammad Saddam Hossain, Fiaz Ahmed, Stavros G. Karakalos, Mark D. Smith, Namrata Pant, Sophya V. Garashchuk, Andrew B, Greytak, Pablo Docampo, Linda S. Shimizu

Faculty Publications

Herein, we report structural, computational, and conductivity studies on urea-directed self-assembled iodinated triphenylamine (TPA) derivatives. Despite numerous reports of conductive TPAs, the challenges of correlating their solid-state assembly with charge transport properties hinder the efficient design of new materials. In this work, we compare the assembled structures of a methylene urea bridged dimer of di-iodo TPA (1) and the corresponding methylene urea di-iodo TPA monomer (2) with a di-iodo mono aldehyde (3) control. These modifications lead to needle shaped crystals for 1 and 2 that are organized by urea hydrogen bonding, π⋯π stacking, I⋯I, and I⋯π interactions as determined by …

Maintaining Yoga Practice For Diabetes Control And Prevention, Gina K. Alexander

Dissertations

Type 2 diabetes mellitus affects millions of individuals, representing a vast burden of disease for the national health care system. Yoga practice has demonstrated potential for diabetes control and prevention, yet few yoga-based studies explore factors affecting maintenance of yoga practice over time.

The purpose of this study was to explore factors influencing the maintenance of yoga practice over time, to clarify the relationship between the social environment and yoga practice, and to examine the influence of a yoga intervention over time on the physical activity of adults with or at risk for type 2 diabetes.

Accelerating High School Students’ Science Career Trajectories Through Non-Formal Science Volunteer Programs, K. Ren Rende, M. Gail Jones, Emma Refvem, Sarah J. Carrier, Megan Ennes

Teacher Education Faculty Publications

Extensive research shows that non-formal science education programs effectively build and sustain long-term interest and persistence in science careers. Framed by expectancy-value theory, this study examined the academic and career outcomes of students who participated in a multi-year volunteer program at a science museum. Twenty-one participants were interviewed about their motivations for volunteering and the impact of participation on their science career trajectories. Data were coded for factors related to expectancy-value including goals, motivations, previous non-formal science experiences, and family attitudes towards science and STEM. Results showed participants of the volunteer program pursued science careers at higher rates than the …

Atomic Layer Deposition And High Sensitivity-Low Energy Ion Scattering For The Determination Of The Surface Silanol Density On Glass And Unsupervised Exploratory Data Analysis With Summary Statistics And Other Methods, Tahereh Gholian Avval

Theses and Dissertations

With the increasing importance of hand-held devices with touch displays, the need for flat panel displays (FPDs) will likely increase in the future. Glass is the most important substrate for FPD manufacturing, where both its bulk and surface properties are critical for its performance. Many properties of the glass used in FPDs are controlled by its surface chemistry. Surface hydroxyls are the most important functional groups on a glass surface, which control processes that occurs on oxide surfaces, including wetting, adhesion, electrostatic charging and discharge, and the rate of contamination. In this dissertation, I present a new approach for determining …

Editorial: Glia-Mediated Neurotoxicity: Uncovering The Molecular Mechanisms, Amit K Srivastava, Barbara Lukomska, Lorraine Iacovitti

Farber Institute for Neuroscience Faculty Papers

No abstract provided.

Elemental Sulfur And Metal Sulfide Minerals For Autotrophic Denitrification: Applications To Aquaculture, Groundwater Treatment, And Domestic Wastewater Treatment, Erica Amah Dasi

USF Tampa Graduate Theses and Dissertations

Nutrient pollution of waterways, from excess N and P, is a global concern that results in harmful impacts the environment, human health, and aquatic animals. This dissertation harnesses sulfur autotrophic denitrification to remove nutrients from groundwater, domestic wastewater, and wastewaters produced from marine recirculating aquaculture systems (RAS). Part 1 evaluates the denitrification performance of woodchips and elemental sulfur in cyclic denitrification filters (WS-CDFs) integrated into marine RAS operated under saline conditions. Part 2 investigates the use of metal sulfide minerals, with and without oyster shells, for supporting nutrient removal from groundwater in batch reactors. Part 3 assesses …

Can Variables From The Electronic Health Record Identify Delirium At Bedside?, Ariba Khan, Kayla Heslin, Michelle Simpson, Michael L. Malone

Journal of Patient-Centered Research and Reviews

Delirium, a common and serious disorder in older hospitalized patients, remains underrecognized. While several delirium predictive models have been developed, only a handful have focused on electronic health record (EHR) data. This prospective cohort study of older inpatients (≥ 65 years old) aimed to determine if variables within our health system’s EHR could be used to identify delirium among hospitalized patients at the bedside. Trained researchers screened daily for delirium using the 3-minute diagnostic Confusion Assessment Method (3D-CAM). Patient demographic and clinical variables were extracted from the EHR. Among 408 participants, mean age was 75 years, 60.8% were female, and …

Lehr Discovers New Species Of Lizard In Peru, Mj Soria

News and Events (Discontinued Series)

No abstract provided.

The Lived Experience Of Parents Of Children With Special Healthcare Needs On Public And Private Insurance: A Phenomenological Study, Regine P. Reaves

Dissertations

Due to recent advances in medical technology, the number of children with special healthcare needs (CSHCN) is steadily growing in the United States. CSHCN comprise more than 40% of overall healthcare costs nationwide, even though this group is only comprised of 16% of the U.S. child population. There are significant differences between private and public health plans in terms of cost, adequacy, and parent satisfaction. As an added benefit, some public and private health insurance plans offer nursing care coordination (or nursing case management) services. The purpose of this study was to understand the experiences of parents of CSHCN enrolled …

Benthic Megafauna Of The Western Clarion-Clipperton Zone, Pacific Ocean, G Bribiesca-Contreras, Tg Dahlgren, Dj Amon, S Cairns, Et Al

School of Biological and Marine Sciences

There is a growing interest in the exploitation of deep-sea mineral deposits, particularly on the abyssal seafloor of the central Pacific Clarion-Clipperton Zone (CCZ), which is rich in polymetallic nodules. In order to effectively manage potential exploitation activities, a thorough understanding of the biodiversity, community structure, species ranges, connectivity, and ecosystem functions across a range of scales is needed. The benthic megafauna plays an important role in the functioning of deep-sea ecosystems and represents an important component of the biodiversity. While megafaunal surveys using video and still images have provided insight into CCZ biodiversity, the collection of faunal samples is …

Manifold Based Deep Learning: Advances And Machine Learning Applications, Navya Nagananda

Theses

Manifolds are topological spaces that are locally Euclidean and find applications in dimensionality reduction, subspace learning, visual domain adaptation, clustering, and more. In this dissertation, we propose a framework for linear dimensionality reduction called the proxy matrix optimization (PMO) that uses the Grassmann manifold for optimizing over orthogonal matrix manifolds. PMO is an iterative and flexible method that finds the lower-dimensional projections for various linear dimensionality reduction methods by changing the objective function. PMO is suitable for Principal Component Analysis (PCA), Linear Discriminant Analysis (LDA), Canonical Correlation Analysis (CCA), Maximum Autocorrelation Factors (MAF), and Locality Preserving Projections (LPP). We extend …

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Adipose Methylome Integrative-Omic Analyses Reveal Genetic And Dietary Metabolic Health Drivers And Insulin Resistance Classifiers., Colette Christiansen, Max Tomlinson, Melissa Eliot, Emma Nilsson, Ricardo Costeira, Yujing Xia, Sergio Villicaña, Olatz Mompeo, Philippa Wells, Juan Castillo-Fernandez, Louis Potier, Marie-Claude Vohl, Andre Tchernof, Julia El-Sayed Moustafa, Cristina Menni, Claire J. Steves, Karl Kelsey, Charlotte Ling, Elin Grundberg, Kerrin S. Small, Jordana T. Bell

Manuscripts, Articles, Book Chapters and Other Papers

BACKGROUND: There is considerable evidence for the importance of the DNA methylome in metabolic health, for example, a robust methylation signature has been associated with body mass index (BMI). However, visceral fat (VF) mass accumulation is a greater risk factor for metabolic disease than BMI alone. In this study, we dissect the subcutaneous adipose tissue (SAT) methylome signature relevant to metabolic health by focusing on VF as the major risk factor of metabolic disease. We integrate results with genetic, blood methylation, SAT gene expression, blood metabolomic, dietary intake and metabolic phenotype data to assess and quantify genetic and environmental drivers …

Gis Automated Delineation And Analysis Of Cancer Service Areas In The United States, Changzhen Wang

LSU Doctoral Dissertations

Delineating a meaningful and reliable geographic unit pertaining to cancer care is essential in examining geographic variations in cancer care for better analysis, management, and planning. Public health researchers have devoted great efforts to defining various service areas, which; however, lack scientific rigor or are unrepresentative of the highly specialized cancer care markets, and their methods have become obsolete in the era of big data and high geo-computation. This study develops the “Spatially Constrained Leiden (ScLeiden)” method, a network community detection algorithm in Geographic Information Systems (GIS), and applies it to delineate a series of coherent cancer service …

A Narrative Review On Yoga: A Potential Intervention For Augmenting Immunomodulation And Mental Health In Covid-19, Indranill Basu-Ray, Kashinath Metri, Dibbendhu Khanra, Rishab Revankar, Kavitha M Chinnaiyan, Nagaratna Raghuram, Mahesh Chandra Mishra, Bhushan Patwardhan, Manjunath Sharma, Ishwar V Basavaraddi, Akshay Anand, Shrinath Reddy, K K Deepak, Marian Levy, Sue Theus, Glenn N Levine, Holger Cramer, Gregory L Fricchione, Nagendra R Hongasandra

Faculty, Staff and Students Publications

BACKGROUND: The ongoing novel coronavirus disease 2019 (COVID-19) pandemic has a significant mortality rate of 3-5%. The principal causes of multiorgan failure and death are cytokine release syndrome and immune dysfunction. Stress, anxiety, and depression has been aggravated by the pandemic and its resultant restrictions in day-to-day life which may contribute to immune dysregulation. Thus, immunity strengthening and the prevention of cytokine release syndrome are important for preventing and minimizing mortality in COVID-19 patients. However, despite a few specific remedies that now exist for the SARS-CoV-2virus, the principal modes of prevention include vaccination, masking, and holistic healing methods, such as …

Therapeutic Targeting Of Macrophage Plasticity Remodels The Tumor-Immune Microenvironment, Hee-Jin Jang, Hyun-Sung Lee, Wendong Yu, Maheshwari Ramineni, Cynthia Y Truong, Daniela Ramos, Taylor Splawn, Jong Min Choi, Sung Yun Jung, Ju-Seog Lee, Daniel Y Wang, Joel M Sederstrom, Massimo Pietropaolo, Farrah Kheradmand, Christopher I Amos, Thomas M Wheeler, R Taylor Ripley, Bryan M Burt

Center for Medical Ethics and Health Policy Staff Publications

Although the majority of patients with advanced lung adenocarcinoma (LUAD) are eligible to receive immune checkpoint blockade, approximately 80% of these tumors are resistant to this therapeutic approach. Insights at the single-cell level into mechanisms that drive LUAD tumorigenesis and the relationship of LUAD histologic heterogeneity to response to immune checkpoint blockade could help identify biomarkers and potential combinational approaches to improve immunotherapy efficacy. Here we used a genetically engineered mouse model that replicates the development of human LUAD through a spectrum of pre-invasive to invasive adenocarcinoma histologic subtypes. A systems onco-immunology approach of integrating the analytical power and unique, …

Brief Intervention To Reduce Fatigue Impact In Patients With Inflammatory Arthritis: Design And Outcomes Of A Single-Arm Feasibility Study, E Dures, S Bridgewater, B Abbott, J Adams, A Berry, Lm Mccracken, S Creanor, S Hewlett, J Lomax, M Ndosi, J Thorn, M Urban, P Ewings

Peninsula Medical School

ObjectivesPatients with inflammatory arthritis report that fatigue is challenging to manage. We developed a manualised, one-to-one, cognitive–behavioural intervention, delivered by rheumatology health professionals (RHPs). The Fatigue - Reducing its Effects through individualised support Episodes in Inflammatory Arthritis (FREE-IA) study tested the feasibility of RHP training, intervention delivery and outcome collection ahead of a potential trial of clinical and cost-effectiveness.MethodsIn this single-arm feasibility study, eligible patients were ≥18 years, had a clinician-confirmed diagnosis of an inflammatory arthritis and scored ≥6/10 on the Bristol Rheumatoid Arthritis Fatigue (BRAF) Numerical Rating Scale (NRS) Fatigue Effect. Following training, RHPs delivered two to four sessions …

Multilingualism And The Social Status Of Women In The City Of Osijek In The 19th And Early 20th Centuries, Ljubica Kordic, Visnja Lachner

Journal of International Women's Studies

The authors strive to present the social status of women in Croatian cities in the 19^th and early 20^th centuries on the example of the multilingual city of Osijek. The main goal of the paper is to determine the social position of women at that time and to examine whether and to which extent it was influenced by their knowledge of three languages spoken in the multilingual milieu of the city: Croatian, German, and Hungarian. The corpus of the research encompasses job announcements and advertisements related to women in two local newspapers in the German language Die Drau …

Reconsidering The Victorian Angel In The Light Of Butler’S Concept Of Performativity, Monia Chouari

Journal of International Women's Studies

Amid the fast changes and repercussions of the French and Industrial Revolutions in the 19^th century, women's critical status in the transitory period in Britain stimulated the Victorian elite, namely women novelists like Elizabeth Gaskell, to raise the complex issue of femininity and womanhood to establish femininity as an agency. Interrogating the predominant concept of a woman as an angel, this study sets forth to examine the mechanisms of the building-up of women characters wrestling with the Victorian ideal of the angel for a sweet home that has been established by leading figures and theorists of domestic ideology such …

Cranial Base Synchondrosis Lacks Pthrp-Expressing Column-Forming Chondrocytes, Shawn A Hallett, Annabelle Zhou, Curtis Herzog, Ariel Arbiv, Wanida Ono, Noriaki Ono

Faculty, Staff and Student Publications

The cranial base contains a special type of growth plate termed the synchondrosis, which functions as the growth center of the skull. The synchondrosis is composed of bidirectional opposite-facing layers of resting, proliferating, and hypertrophic chondrocytes, and lacks the secondary ossification center. In long bones, the resting zone of the epiphyseal growth plate houses a population of parathyroid hormone-related protein (PTHrP)-expressing chondrocytes that contribute to the formation of columnar chondrocytes. Whether PTHrP+ chondrocytes in the synchondrosis possess similar functions remains undefined. Using Pthrp-mCherry knock-in mice, we found that PTHrP+ chondrocytes predominantly occupied the lateral wedge-shaped area of the synchondrosis, unlike …

Psma As A Target For Advanced Prostate Cancer: A Systematic Review, Safiya-Hana Belbina, Mia Rose Schmolze, Sofia Gereta, Aaron A. Laviana

School of Medicine Publications

Objective: Prostate-specific membrane antigen (PSMA) is a cell-surface protein widely expressed on most prostate cancer cells that has rapidly emerging clinical utility in the realm of prostate cancer. This systematic review aims to evaluate the efficacy as well as cost-effectiveness of PSMA in the roles of diagnosis and treatment in prostate cancer management.

Background: The use of PSMA in the initial staging of patients, early detection of recurrence, and response monitoring are critical to improving prostate cancer treatment. We performed a systematic review of the role of Gallium-68 (⁶⁸Ga)-PSMA in the initial detection of prostate cancer and detection …

Α-Synuclein Conformational Plasticity: Physiologic States, Pathologic Strains, And Biotechnological Applications, Amanda Li, Cyrus Rastegar, Xiaobo Mao

2020-Current year OA Pubs

α-Synuclein (αS) is remarkable for both its extensive conformational plasticity and pathologic prion-like properties. Physiologically, αS may populate disordered monomeric, helically folded tetrameric, or membrane-bound oligomeric states. Pathologically, αS may assemble into toxic oligomers and subsequently fibrils, the prion-like transmission of which is implicated in a class of neurodegenerative disorders collectively termed α-synucleinopathies. Notably, αS does not adopt a single "amyloid fold", but rather exists as structurally distinct amyloid-like conformations referred to as "strains". The inoculation of animal models with different strains induces distinct pathologies, and emerging evidence suggests that the propagation of disease-specific strains underlies the differential pathologies observed …

Development Of A Non-Dairy Yogurt Alternative Using High Protein Brown And White Rice Flour, Anita Morris

LSU Doctoral Dissertations

There is a great demand for plant-based yogurt alternatives (YAs) due to societal prevalence of milk sensitivities and allergies as well as some consumers abstaining from animal-derived products. Producing YAs from rice flour has considerable potential because (1) rice is not a major food allergen, (2) using rice flour is more economical compared to plant milks, the main ingredient in commercially available YAs, and (3) there are no rice-based yogurt alternatives in today’s marketplace. The overall goals of this study were to develop probiotic YAs from brown and white rice flours, and to evaluate their storage stability, probiotic’s survival in …

Synchronous Retreat Of Southeast Greenland's Peripheral Glaciers, Julia Liu, Ellyn Enderlin, Hans-Peter Marshall, Andre Khalil

Geosciences Faculty Publications and Presentations

Recently, scientific attention has focused on estimating Greenland's dynamic mass loss through changes to flow speeds, thickness, and length on its marine outlet glaciers. For the ice sheet outlet glaciers, dynamic mass loss has been found to be highly sensitive to changes in climate and individual glacier geometry. For the ice-sheet-independent marine glaciers around Greenland's periphery, dynamic mass loss is presently overlooked. Here, we apply an open-source, automated method of measuring glacier length changes using satellite imagery, to produce highly detailed records of length changes for 135 peripheral marine glaciers in southeast Greenland. We find evidence for anomalous retreat across …

Development Of The Cooperative Adoption Factors Instrument To Measure Factors Associated With Instructional Practice In The Context Of Institutional Change, John P. Ziker, Brittnee Earl, Karl Mertens, Susan E. Shadle

Anthropology Faculty Publications and Presentations

Background: Many institutional and departmentally focused change efforts have sought to improve teaching in STEM through the promotion of evidence-based instructional practices (EBIPs). Even with these efforts, EBIPs have not become the predominant mode of teaching in many STEM departments. To better understand institutional change efforts and the barriers to EBIP implementation, we developed the Cooperative Adoption Factors Instrument (CAFI) to probe faculty member characteristics beyond demographic attributes at the individual level. The CAFI probes multiple constructs related to institutional change including perceptions of the degree of mutual advantage of taking an action (strategic complements), trust and interconnectedness among colleagues …

Alumnus Makes Major Gifts To Help Fulfill Vision, Tina H. Hahn

University of Mississippi News

John Covert provides support to kitchen renovation, Ole Miss athletics

A Method For Bridging Population-Specific Genotypes To Detect Gene Modules Associated With Alzheimer's Disease, Yulin Dai, Peilin Jia, Zhongming Zhao, Assaf Gottlieb

Faculty, Staff and Student Publications

BACKGROUND: Genome-wide association studies have successfully identified variants associated with multiple conditions. However, generalizing discoveries across diverse populations remains challenging due to large variations in genetic composition. Methods that perform gene expression imputation have attempted to address the transferability of gene discoveries across populations, but with limited success.

METHODS: Here, we introduce a pipeline that combines gene expression imputation with gene module discovery, including a dense gene module search and a gene set variation analysis, to address the transferability issue. Our method feeds association probabilities of imputed gene expression with a selected phenotype into tissue-specific gene-module discovery over protein interaction …

Amplification Of Black Vulture (Coragyps Atratus) Dna From Regurgitated Food Pellets, Daniel R. Taylor, Bryan M. Kluever, John S. Humphrey, Iona M. Hennessy, Amber Sutton, William E. Bruce, Antoinette J. Piaggio

United States Department of Agriculture Wildlife Services: Staff Publications

Studies that rely on noninvasive collection of DNA for birds often use feces or feathers. Some birds, such as vultures, regurgitate undigested matter in the form of pellets that are commonly found under roost sites. Our research demonstrates that regurgitated pellets are a viable, noninvasive source of DNA for molecular ecology studies of vultures. Our objectives were to amplify 5 microsatellite loci designed for distinguishing Turkey Vultures (Cathartes aura) and Black Vultures (Coragyps atratus) in a single, multiplexed PCR, and to determine how long the target nuclear DNA persists after a vulture pellet is regurgitated and …

A Systems Approach To Mapping Uk Regional Innovation Ecosystems For Policy Insight, Dan Arthur, Jonathan Moizer, Jonathan Lean

Plymouth Business School

The literature on innovation and regional economic development shows widespread references to ‘systems’ but relatively little application of systems thinking and problem structuring methods. Innovation models are thus under-theorised with operationally-based maps that link the structure of innovation systems to behaviour and possible policy levers. This conceptual paper addresses this shortfall by applying a systems mapping approach to regional innovation ecosystems which sets out the structural drivers and actor inter-relationships in regional economies with universities acting as focal points for knowledge application. A causal feedback map is hypothesised from participative research and the innovation literature, providing an integrative framework and …

Variation In Fatty Acid Concentrations In Grasses Legume And Forbs Agronomy-12-01693-V3, Edward Barrow Rayburn

Faculty & Staff Scholarship

No abstract provided.