Digital Commons Network^™

Is The Endangered Species Act Endangered In The Age Of Strict Federalism? A Florida Perspective On The Recent Commerce Clause Challenges To The Esa, Kevin M. Shuler

Florida Law Review

No abstract provided.

Moving Beyond Rhetoric, Christopher Wolfe

Florida Law Review

No abstract provided.

Unreasonable Seizure: "Stop And Identify" Statutes Create And Illusion Of Safety By Sacrificing Real Privacy, Peter Koclanes

Florida Law Review

No abstract provided.

The Feminist Misspeak Of Sexual Harassment, Linda Kelly Hill

Florida Law Review

No abstract provided.

Patriotism, Nationalism, And The War On Terror: A Mild Plea In Avoidance, Winston P. Nagan, Craig Hammer

Florida Law Review

No abstract provided.

For God, For Country, For Universalism: Sovereignty As Solidarity In Our Age Of Terror, Maxwell O. Chibundu

Florida Law Review

No abstract provided.

Beyond The Liberal And Communitarian Impasse: A Framework And Vision For Public Health, James F. Childress, Ruth Gaare Bernheim

Florida Law Review

No abstract provided.

Puppy Love: Bioterrorism, Civil Rights, And Public Health, George J. Annas

Florida Law Review

No abstract provided.

When Terrorism Threatens Health: How Far Are Limitations On Personal And Economic Liberties Justified?, Lawrence O. Gostin

Florida Law Review

No abstract provided.

Prolegomenon To A Memetic Theory Of Copyright: Comments On Lawrence Lessig's The Creative Commons, Thomas F. Cotter

Florida Law Review

No abstract provided.

Assisted Reproductive Technologies And The Pitfalls Of Unregulated Biomedical Innovation, Lars Noah

Florida Law Review

This Article suggests that the time has come to reconsider the safety and effectiveness of fertility drugs in order to combat some of the continuing problems arising from the overly aggressive use of assisted reproductive technologies, especially the health hazards associated with multifetal pregnancies. After critically assessing the arguments made by some commentators about the power of malpractice law to curb any abuses by fertility clinics and specialists, the Article concludes that the Food and Drug Administration should consider restricting or withdrawing pharmaceutical products used to induce ovulation. Although such a drastic move would not prevent the continued use of …

Across The Borders: Immigrant Status And Identity In Law And Latcrit Theory, Ruben J. Garcia

Florida Law Review

No abstract provided.

The Child Citizenship Act And The Family Reunification Act: Valuing The Citizen Child As Well As The Citizen Parent, Victor C. Romero

Florida Law Review

No abstract provided.

Migrations, Citizens And Latinos/As: The Sojourner's Truth And Other Stories, Robert S. Chang

Florida Law Review

No abstract provided.

Latcritical Encounters With Culture, In North-South Frameworks, Pedro A. Malavet

Florida Law Review

No abstract provided.

Genome-Wide Association Study In Minority Children With Asthma Implicates Dnah5 In Bronchodilator Responsiveness, Jaehyun Joo, Angel C. Y Mak, Shujie Xiao, Patrick M. Sleiman, Donglei Hu, Scott Huntsman, Celeste Eng, Mengyuan Kan, Avantika R. Diwakar, Jessica A. Lasky-Su, Scott T. Weiss, Joanne E. Sordillo, Ann C. Wu, Michelle Cloutier, Glorisa Canino, Erick Forno, Juan C. Celedón, Max A. Seibold, Hakon Hakonarson, Keoki L. Williams, Esteban G. Burchard, Blanca E. Himes

Center for Individualized and Genomic Medicine Research Articles

Variability in response to short-acting β(2)-agonists (e.g., albuterol) among patients with asthma from diverse racial/ethnic groups may contribute to asthma disparities. We sought to identify genetic variants associated with bronchodilator response (BDR) to identify potential mechanisms of drug response and risk factors for worse asthma outcomes. Genome-wide association studies of bronchodilator response (BDR) were performed using TOPMed Whole Genome Sequencing data of the Asthma Translational Genomic Collaboration (ATGC), which corresponded to 1136 Puerto Rican, 656 Mexican and 4337 African American patients with asthma. With the population-specific GWAS results, a trans-ethnic meta-analysis was performed to identify BDR-associated variants shared across the …

Residents’ Satisfaction With Apartment Living In Kuwait: A Study Of The Design Of Jaber Al Ahmad Apartments, Fawzi Alzamil, Qutaiba E. Al-Shaheen

Emirates Journal for Engineering Research

This study examines public housing in Kuwait and Jaber Al Ahmad apartments housing project. It tries to figure out how housing provision, citizen expectations, and satisfaction are linked.

Kuwait's government provide housing for Kuwaiti married couples as part of a welfare program. This goal has proven difficult to achieve, with a waiting list of over 100,000 people. While the majority of applicants apply for a residential plot and a housing loan to build a single-family home, a small number of candidates apply for the apartment unit’s alternative.

The government's capacity to reduce housing demand hinges on its ability to persuade …

The Weaponization Of Rape: Military Culture, Tactical Warfare, And Legal Justice, Claire Velte

International Relations Summer Fellows

The long-accepted narrative of wartime rape is one of inevitability, with sexual violence committed at the hands of soldiers during conflict being written off as an unavoidable side-effect of war. In reality, however, wartime rape can be systematically and tactically employed by military forces to terrorize the bodies of their enemies, often as an attempt to physically and psychologically destroy certain populations. The act itself, when employed tactically, is legally recognized as a weapon of war—and the rape of civilians by military forces was legally designated as a crime against humanity in 1993—yet rape continues to be utilized in conflict …

Immune Cell-Protein Interactions In Alzheimer’S Disease, Kapur Dhami

Dissertations

Misfolded protein aggregates are one of the significant contributing factors in many neurogenerative diseases including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and others. My PhD research project was to study various aspects of amyloid-β peptide, a 40-42-residue peptide and the primary component of the senile plaques found in Alzheimer’s disease (AD) brains. One objective of my research was to purify and characterize the intermediate Aβ42 species using an array of biophysical techniques like size exclusion chromatography, fluorescence assays, circular dichroism, cellular assays, and protein assays. The other major research thrust of my project was to study the role of microglial …

Regulated Dicing Of Pre-Mir-144 Via Reshaping Of Its Terminal Loop., Renfu Shang, Dmitry A Kretov, Scott I Adamson, Thomas Treiber, Nora Treiber, Jeffrey Vedanayagam, Jeffrey H Chuang, Gunter Meister, Daniel Cifuentes, Eric C Lai

Faculty Research 2022

Although the route to generate microRNAs (miRNAs) is often depicted as a linear series of sequential and constitutive cleavages, we now appreciate multiple alternative pathways as well as diverse strategies to modulate their processing and function. Here, we identify an unusually profound regulatory role of conserved loop sequences in vertebrate pre-mir-144, which are essential for its cleavage by the Dicer RNase III enzyme in human and zebrafish models. Our data indicate that pre-mir-144 dicing is positively regulated via its terminal loop, and involves the ILF3 complex (NF90 and its partner NF45/ILF2). We provide further evidence that this regulatory switch involves …

Bbt Acoustic Alternative Top Bracing Cadd Data Set-Norev-2022jun28, Bill Hemphill

STEM Guitar Project’s BBT Acoustic Kit

This electronic document file set consists of an overview presentation (PDF-formatted) file and companion video (MP4) and CADD files (DWG & DXF) for laser cutting the ETSU-developed alternate top bracing designs and marking templates for the STEM Guitar Project’s BBT (OM-sized) standard acoustic guitar kit. The three (3) alternative BBT top bracing designs in this release are
(a) a one-piece base for the standard kit's (Martin-style) bracing,
(b) 277 Ladder-style bracing, and
(c) an X-braced fan-style bracing similar to traditional European or so-called 'classical' acoustic guitars.

The CADD data set for each of the three (3) top bracing designs includes …

Further Flattening Of A Degraded, Turbid Reef System Following A Severe Coral Bleaching Event, Andrew G. Bauman, Fraser A. Januchowski-Hartley, Aaron Teo, Peter A. Todd

Marine & Environmental Sciences Faculty Articles

Increasing incidence of severe coral bleaching events caused by climate change is contributing to extensive coral losses, shifts in species composition and widespread declines in the physical structure of coral reef ecosystems. With these ongoing changes to coral communities and the concomitant flattening of reef structural complexity, understanding the links between coral composition and structural complexity in maintaining ecosystem functions and processes is of critical importance. Here, we document the impacts of the 2016 global-scale coral bleaching event on seven coral reefs in Singapore; a heavily degraded, turbid reef system. Using a combination of field-based surveys, we examined changes in …

Characterization Of In Vivo Damage On Retrieved Total Shoulder Glenoid Liners, Eric Cheatwood, Gerard Simon, Lynn Crosby, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

An attempt was made to retrieve glenoid liners from revision surgery to undertake a retrospective study to measure the resulting in vivo damage. Since the glenoid liners are circumferential, the curvature changes at every point in the component, an “assisting arm” was designed to hold the liner firmly, thus allowing accurate microscopic measurements. We characterized the damage in terms of pitting, embedded debris, complete fracture, abrasion, deformation, delamination, burnishing, grooving, and scratching that took place mutually exclusively. This study of 26 liners showed embedded debris was the most underrated damage mode found on the liners, followed by pitting and abrasion, …

Exercise Effects On Cognition In Older African Americans: A Pilot Randomized Trial, Kathryn L. Gwizdala, Robert Brouillete, Robbie Beyl, William Johnson, Callie Hebert, Leah Carter, Melissa Harris, Robert L. Newton, Owen T. Carmichael

Clinical Research Faculty Publications

Introduction: Regular physical activity lowers risk for cognitive decline and neurodegenerative disorders. Older African Americans (AAs) have been underrepresented in trials that increased physical activity to improve cognitive outcomes. Methods: 56 sedentary, older, cognitively healthy AAs (avg. 69.2 ± 3.4 yrs. old) were randomized in 1:1 ratio into either a 12-week successful aging group (SAG) or a 12-week physical activity group (PAG). Participants in SAG attended weekly 60-min educational sessions in which healthy aging topics were discussed. Participants in PAG attended supervised physical activity sessions twice per week at local YMCAs (90–120 min/week) and were prescribed 2–3 days per week …

Effect Of Ultraviolet Light Treatment On Microbiological Safety And Quality Of Fresh Produce: An Overview, Veerachandra Yemmireddy, Achyut Adhikari, Juan Moreira

Faculty Publications

Fresh and fresh-cut fruits and vegetables have been associated in several foodborne illness outbreaks. Although investigations from those outbreaks reported that the contamination with pathogenic microorganisms may occur at any point in the farm to fork continuum, effective control strategies are still being widely investigated. In that direction, the concept of hurdle technology involving a sequence of different interventions have been widely explored. Among those interventions, ultraviolet (UV) light alone or in combination with other treatments such as use of organic acids or sanitizer solutions, has found to be a promising approach to maintain the microbiological safety and quality of …

Mir-489 Confines Uncontrolled Estrogen Signaling Through A Negative Feedback Mechanism And Regulates Tamoxifen Resistance In Breast Cancer, Mithil Soni, Ozge Saatci, Gourab Gupta, Yogin Patel, Manikanda Raja Keerthi Raja, Jie Li, Xinfeng Liu, Peisheng Xu Ph.D., Hongjun Wang, Daping Fan, Ozgur Sahin, Hexin Chen

Faculty Publications

Approximately 75% of diagnosed breast cancer tumors are estrogen-receptor-positive tumors and are associated with a better prognosis due to response to hormonal therapies. However, around 40% of patients relapse after hormonal therapies. Genomic analysis of gene expression profiles in primary breast cancers and tamoxifen-resistant cell lines suggested the potential role of miR-489 in the regulation of estrogen signaling and development of tamoxifen resistance. Our in vitro analysis showed that loss of miR-489 expression promoted tamoxifen resistance, while overexpression of miR-489 in tamoxifen-resistant cells restored tamoxifen sensitivity. Mechanistically, we found that miR-489 is an estrogen-regulated miRNA that negatively regulates estrogen receptor …

July 22, 2022 Ereporter, University Of Alabama At Birmingham

eReporter (campus newsletter)

No abstract provided.

Completing Single-Cell Dna Methylome Profiles Via Transfer Learning Together With Kl-Divergence, Sanjeeva Dodlapati, Zongliang Jiang, Jiangwen Sun

Faculty Publications

The high level of sparsity in methylome profiles obtained using whole-genome bisulfite sequencing in the case of low biological material amount limits its value in the study of systems in which large samples are difficult to assemble, such as mammalian preimplantation embryonic development. The recently developed computational methods for addressing the sparsity by imputing missing have their limits when the required minimum data coverage or profiles of the same tissue in other modalities are not available. In this study, we explored the use of transfer learning together with Kullback-Leibler (KL) divergence to train predictive models for completing methylome profiles with …

Water, David Hunkeler

Micro-Nano Plastics in Water: Characterization, Cure and Prevention

What is Water? Why is it Important? How do we Maintain it? What Examples do we Have?

This book is intended for those who have an interest, or seek some guidance, in maintaining water as a resource. It is geared to individuals with a high school science education or general technical curiosity, though it might be of interest to either volunteer/appointees or elected officials who have general oversight of their local town/village municipal water/wastewater systems in order to gain a better understanding of what is involved in water treatment. It begins by presenting a concise history of water, including the …

Use Of Autoreactive Antibodies In Blood Of Patients With Pancreatic Intraductal Papillary Mucinous Neoplasms (Ipmn) For Grade Distinction And Detection Of Malignancy, Niall Brindl, Henning Boekhoff, Andrea S Bauer, Matthias M Gaida, Hien Dang, Jörg Kaiser, Jörg D Hoheisel, Klaus Felix

Department of Surgery Faculty Papers

(1) Background: A reliable non-invasive distinction between low- and high-risk pancreatic intraductal papillary mucinous neoplasms (IPMN) is needed to effectively detect IPMN with malignant potential. This would improve preventative care and reduce the risk of developing pancreatic cancer and overtreatment. The present study aimed at exploring the presence of autoreactive antibodies in the blood of patients with IPMN of various grades of dysplasia. (2) Methods: A single-center cohort was studied composed of 378 serum samples from patients with low-grade IPMN (n = 91), high-grade IPMN (n = 66), IPMN with associated invasive cancer (n = 30), pancreatic …