Digital Commons Network^™

Implementing A Smoking Cessation Protocol In Type 2 Diabetics In A Podiatry Clinic Using The Five A'S Model, Guerlyne Henson

Dissertations

Smoking is an independent risk factor for DMT2 making it essential for providers to address smoking cessation consistently. The purpose of this quantitative, quasiexperimental quality improvement (QI) project was to evaluate if or to what degree the implementation of a tobacco cessation protocol using the Five A's model would impact the patient's motivation, nicotine dependence, and provider compliance with assessing tobacco use in adult diabetic smokers in a podiatry clinic for four weeks in the northeastern United States. The transtheoretical model (TTM) was utilized to evaluate patient motivation to quit smoking and determine appropriate cessation interventions. Data on the motivation …

Fictional Escapism And Identity Formation: A Duoethnographic Exploration Of Stories And Adolescent Development, Cammie J. Lawton, Leia K. Cain

The Qualitative Report

Young Adult Literature has often been utilized to explore reader responses especially in attention to how fiction provides space to explore identity and one’s place within a larger societal context. In this duoethnography, we explored the importance of children and young adult literature’s influence on our own identity development. We share our primary findings that highlight the ways reading stories has provided escape, space for self-discovery and questioning, as well as pathways of learning to cultivate empathy and work towards social justice. We agree with Ellis’s (2014) argument that storytellers must share stories in a way that makes lessons or …

Bio-Inspired Micromachined Volumetric Flow Sensor With A Big Dynamic Range For Intravenous Systems, Lansheng Zhang, Yingchen Yang, Georgios A. Bertos, Chang Liu, Huan Hu

Mechanical Engineering Faculty Publications

Real-time monitoring of drug delivery in an intravenous infusion system can prevent injury caused by improper drug doses. As the medicine must be administered into the vein at different rates and doses in different people, an ideal intravenous infusion system requires both a low flow rate and large dynamic range monitoring. In this study, a bio-inspired and micromachined volumetric flow sensor is presented for the biomedical application of an intravenous system. This was realized by integrating two sensing units with different sensitivities on one silicon die to achieve a large dynamic range of the volumetric flow rate. The sensor was …

The Density Of States Method In Yang-Mills Theories And First Order Phase Transitions, David Mason, Biagio Lucini, Maurizio Piai, Enrico Rinaldi, Davide Vadacchino

School of Engineering, Computing and Mathematics

Extensions of the standard model that lead to first-order phase transitions in the early universe can produce a stochastic background of gravitational waves, which may be accessible to future detectors. Thermodynamic observables at the transition, such as the latent heat, can be determined by lattice simulations, and then used to predict the expected signatures in a given theory. In lattice calculations, the emergence of metastabilities in proximity of the phase transition may make the precise determination of these observables quite challenging, and may lead to large uncontrolled numerical errors. In this contribution, we discuss as a prototype lattice calculation the …

Composite Dynamics In Sp(2N) Gauge Theories, Jong Wan Lee, Ed Bennett, Deog Ki Hong, Ho Hsiao, C. J.David Lin, Biagio Lucini, Maurizio Piai, Davide Vadacchino

School of Engineering, Computing and Mathematics

Sp(2N) gauge theories with fermonic matter provide an ideal laboratory to build extensions of the standard model based on novel composite dynamics. Examples include composite Higgs along with top partial compositeness and composite dark matter. Without fermions, their study also complements those based on SU(Nc) gauge theories with which they share a common sector in the large Nc = 2N limit. We report on our recent progress in the numerical studies of Sp(2N) gauge theories discretised on a four-dimensional Euclidean lattice. In particular, we present preliminary results for the low-lying mass spectra of mesons and chimera baryons in the theories …

Preface, Alexander Belton, Uwe Franz

School of Engineering, Computing and Mathematics

No abstract provided.

Late-Stage Functionalization Through Click Chemistry Provides Glut5-Targeting Glycoconjugate As A Potential Pet Imaging Probe, Adelina Oronova, Marina Tanasova

Michigan Tech Publications, Part 1

The targeting of facilitative sugar transporters (GLUTs) has been utilized in the development of tools for diagnostics and therapy. The interest in this area is promoted by the phenomenon of alterations in cellular metabolic processes that are linked to multitudes of metabolic disorders and diseases. However, nonspecific targeting (e.g., glucose-transporting GLUTs) leads to a lack of disease detection efficiency. Among GLUTs, GLUT5 stands out as a prominent target for developing specific molecular tools due to its association with metabolic diseases, including cancer. This work reports a non-radiolabeled fluoride (19F) coumarin-based glycoconjugate of 2,5-anhydro-D-mannitol as a potential PET imaging probe that …

Investigation, Detection And Prevention Of Online Child Sexual Abuse Material: A Comprehensive Survey, Vuong Ngo, Christina Thorpe, Cach N. Dang, Susan Mckeever

Conference papers

Child sexual abuse inflicts lifelong devastating consequences for victims and is a growing social concern. In most countries, child sexual abuse material (CSAM) distribution is illegal. As a result, there are many research papers in the literature which proposed technologies to detect and investigate CSAM. In this survey, a comprehensive search of the peer reviewed journal and conference paper databases (including preprints) is conducted to identify high-quality literature. We use the PRISMA methodology to refine our search space to 2,761 papers published by Springer, Elsevier, IEEE and ACM. After iterative reviews of title, abstract and full text for relevance to …

New Prospect Ny Llc V. Garcia

All Decisions

No abstract provided.

Period 2 Regulates Low-Dose Radioprotection Via Per2/Pgsk3Β/Β-Catenin/Per2 Loop, Aris T Alexandrou, Yixin Duan, Shanxiu Xu, Clifford Tepper, Ming Fan, Jason Tang, Jonathan Berg, Wassim Basheer, Tyler Valicenti, Paul F Wilson, Matthew A Coleman, Andrew T Vaughan, Loning Fu, David J Grdina, Jefferey Murley, Aijun Wang, Gayle Woloschak, Jian Jian Li

Faculty, Staff and Students Publications

During evolution, humans are acclimatized to the stresses of natural radiation and circadian rhythmicity. Radiosensitivity of mammalian cells varies in the circadian period and adaptive radioprotection can be induced by pre-exposure to low-level radiation (LDR). It is unclear, however, if clock proteins participate in signaling LDR radioprotection. Herein, we demonstrate that radiosensitivity is increased in mice with the deficient Period 2 gene (Per2def) due to impaired DNA repair and mitochondrial function in progenitor bone marrow hematopoietic stem cells and monocytes. Per2 induction and radioprotection are also identified in LDR-treated Per2wt mouse cells and in human skin (HK18) and breast (MCF-10A) …

Registry-Based Cohort Study Of Alpha-1 Antitrypsin Deficiency Prevalence, Incidence And Mortality In Denmark 2000-2018, John Acquavella, Emese Vágó, Henrik Toft Sorensen, Erzsébet Horváth-Puhó, Gregory P. Hess

College of Population Health Faculty Papers

OBJECTIVE: To estimate the prevalence of diagnosed alpha-1 antitrypsin deficiency (dAATD) in Denmark as of 31 December 2018, and dAATD incidence and mortality from 1 January 2000 to 31 December 2018.

STUDY DESIGN AND SETTING: We used the Danish National Patient Registry to identify patients with dAATD based on the International Classification of Diseases, 10th Revision (ICD-10) code E88.0A and the Danish Civil Registration System (CRS) for population counts and vital status. We estimated dAATD prevalence, incidence and mortality. We compared mortality among patients with dAATD and an age-matched and sex-matched cohort extracted from the Danish CRS. We conducted a …

Greenhouse Biocontrol In Utah: Beneficial Insects And The Pests They Target, Marion Murray

All Current Publications

This guide provides information on biocontrol in Utah and pests that are targeted by beneficial pests, such as aphids, fungus gnats, mealybugs, scales, spider mites, thrips, whiteflies. Symptoms, monitoring, lifecycles, and biocontrol options are included.

Fargo Moorhead Ballet To Perform Jan. 28, Communications And Marketing

Campus News Archive

No abstract provided.

Digital Medicine System In Veterans With Severe Mental Illness: Feasibility And Acceptability Study, Sarah Gonzales, Olaoluwa O Okusaga, J Corey Reuteman-Fowler, Megan M Oakes, Jamie N Brown, Scott Moore, Allison A Lewinski, Cristin Rodriguez, Norma Moncayo, Valerie A Smith, Shauna Malone, Justine List, Raymond Y Cho, Amy S Jeffreys, Hayden B Bosworth

Staff and Researcher Publications

Background: Suboptimal medication adherence is a significant problem for patients with serious mental illness. Measuring medication adherence through subjective and objective measures can be challenging, time-consuming, and inaccurate.

Objective: The primary purpose of this feasibility and acceptability study was to evaluate the impact of a digital medicine system (DMS) among Veterans (patients) with serious mental illness as compared with treatment as usual (TAU) on medication adherence.

Methods: This open-label, 2-site, provider-randomized trial assessed aripiprazole refill adherence in Veterans with schizophrenia, schizoaffective disorder, bipolar disorder, or major depressive disorder. We randomized 26 providers such that their patients either received TAU or …

On Kernel-Based Estimator Of Odds Ratio Using Different Stratified Sampling Schemes, Abbas Eftekharian, Hani Samawi, Haresh Rochani

Biostatistics, Epidemiology & Environmental Health Sciences: Faculty Publications

The kernel-based estimator of Cochran Mantel-Haenszel odds ratio based on stratified simple and ranked set sampling is proposed. The expectation and variance of the estimator are analytically obtained. Using a simulation study, the estimator based on stratified ranked set sampling is more efficient than its counterpart based on stratified simple random sampling. Finally, the estimator's performance is investigated by using base deficit data.

The Discrimination Of Self From Other As A Component Of Empathy., Charlotte Little, Elizaveta Solomonova, Maiya Jordan, Natalie Klein, Ben Jennings, Gunnar Schmidtmann, Héctor Leos, Ian Gold

School of Health Professions

Despite the centrality of empathy in human social life, there is no widely agreed definition or characterization of the concept of empathy. A common thread in many of the proposed definitions, however, is that empathy presupposes the discrimination of self and other on the grounds that, to empathize with another individual, the mental state of the target individual must first be distinguished from the empathizer's own mental state. The purpose of this study is to investigate this proposal empirically. We employed a paradigm in which participants rated the emotional valence and degree of arousal of 93 facial expressions of mental …

Density And Climate Effects On Age‐Specific Survival And Population Growth: Consequences For Hibernating Mammals, F. J. Combe, R. Juškaitis, R. C. Trout, S. Bird, J. S. Ellis, J. Norrey, N Al‐Fulaij, I. White, W. E. Harris

School of Biological and Marine Sciences

The impact of factors such as density dependence, food availability and weather are known to be important for predicting population change in a wide range of species. However, a challenge in ecology is understanding the contributory and interactive role of these drivers on populations. This is necessary to design effective conservation and management strategies. Using data from long-term studies of five hazel dormouse Muscardinus avellanarius populations in Europe, we tested the relationship between population density and weather and their impact on demographic rates. We used an integrated population modelling approach, estimating age-specific overwinter survival, annual population growth and fecundity rates. …

Pests Of Hemp In Utah, Marion Murray, Macahl Evans, Claudia Nischwitz, Austin Taylor, Cody Zesiger

All Current Publications

This guide includes information on insect and disease pests of hemp, organized by pest group. Much of the content is a result of a two-year arthropod and plant disease survey of field-grown hemp operations in northern Utah. Some pests included in this guide were not found in that survey but may be likely to occur in the future. Beneficials and natural enemies are also covered, and information on pesticides is included.

Reindeer From Alaska Are Brought To Sun Valley, John W. Lundin

Works by Local Authors

No abstract provided.

Effectiveness Of Soluble Ctla-4-Fc In The Inhibition Of Bone Marrow T-Cell Activation In Context Of Indoleamine 2.3-Dioxygenase (Ido) And Cd4+Foxp3+ Treg Induction, Magdalena Massalska, Marzena Ciechomska, Ewa Kuca-Warnawin, Tomasz Burakowski, Anna Kornatka, Anna Radzikowska, Dariusz Pawlak, Barbara Muz, Adrianna Loniewska-Lwowska, Andrzej Palucha, Pawel Maldyk, Wlodzimierz Maslinski

2020-Current year OA Pubs

BACKGROUND: Rheumatoid arthritis (RA) is a chronic autoimmune disease with systemic inflammation finally resulting in damaged joints. One of the RA development models suggests bone marrow (BM) as a place of inflammation development further leading to disease progression. We aimed to investigate the potential of CTLA-4-Fc molecule in inducing tolerogenic milieu in BM measured as indoleamine 2,3-dioxygenase (IDO) expression, CD4

METHODS: Bone marrow mononuclear cells (BMMC) were stimulated by pro-inflammatory cytokines and CTLA-4-Fc. Next IDO expression, CD4

RESULTS: We found that CTLA-4-Fc and IFN-γ stimulation results in IDO production by BMMC. CTLA-4-Fc induced tryptophan catabolism can inhibit mitogen-induced CD4

CONCLUSION: …

Stakeholder Perspectives On The Demand And Supply Factors Driving Substandard And Falsified Blood Pressure Lowering Medications In Nigeria: A Qualitative Study, Grace Shedul, Olutobi Adekunle Sanuade, Eugenia N Ugwuneji, Tunde M Ojo, Aishwarya Vijay, Patrick Ponzing, Inuwa Okpe, Gabriel Lamkur Shedul, Mark D Huffman, Dike Ojji, Lisa R Hirschhorn

2020-Current year OA Pubs

OBJECTIVES: Although substandard and falsified (SF) blood pressure (BP) lowering medications are a global problem, qualitative research exploring factors driving this in Nigeria has not been reported. This study provides information on factors driving demand for and supply of low-quality BP lowering medications in Nigeria and potential strategies to address these factors.

METHODS: This was a cross-sectional qualitative study. Between August 2020 and September 2020, we conducted 11 in-depth interviews and 7 focus group discussions with administrators of health facilities, major manufacturers and distributors of BP lowering medications, pharmacists, drug regulators, patients and primary care physicians purposively sampled from the …

Myocardial Contractility Pattern Characterization In Radiation-Induced Cardiotoxicity Using Magnetic Resonance Imaging: A Pilot Study With Contractix, El-Sayed H Ibrahim, Antonio Sosa, Sherry-Ann Brown, Dayeong An, Slade Klawikowski, John Baker, Carmen Bergom

2020-Current year OA Pubs

Radiation therapy (RT) plays an integral role in treating thoracic cancers, despite the risk of radiation-induced cardiotoxicity. We hypothesize that our newly developed magnetic resonance imaging (MRI)-based contractility index (ContractiX) is a sensitive marker for early detection of RT-induced cardiotoxicity in a preclinical rat model of thoracic cancer RT. Adult salt-sensitive rats received image-guided heart RT and were imaged with MRI at 8 weeks and 10 weeks post-RT or sham. The MRI exam included cine and tagging sequences to measure left-ventricular ejection fraction (LVEF), mass, myocardial strain, and ContractiX. Furthermore, ventricular torsion, diastolic strain rate, and mechanical dyssynchrony were measured. …

Editorial - Sure Journal Vol 4, Anne M. Friel

SURE Journal: Science Undergraduate Research Experience Journal

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The Interaction Of Adipose Derived Stem Cells And Breast Cancer, Natasha Cunningham, Ava O'Meara, Cathy L. Brougham

SURE Journal: Science Undergraduate Research Experience Journal

Introduction: Mesenchymal stem cells are adult stem cells capable of self-renewal and multilineage differentiation (Schweizer et al., 2015). Adipose derived stem cells have been used in breast reconstruction following surgical intervention in breast cancer patients. MicroRNAs have been linked to gene regulation essential in oncogenic, and tumour suppression as well as cell signalling pathways in BC.

Aim: To research the hypothesis of ADSCs and their therapeutic properties in BC patients.

Methods: Proliferation assays were carried out to demonstrate how ADSC conditioned media influenced BC cell lines MDA-MB-231, SKBR3, and T47D. The expression of six miRNAs (miR-21, miR-133, miR-222, miR-146, miR-221, …

An Evaluation Of The Enjoyment Levels Of Participants Of Lifelab, A Health Literacy Intervention For Socially Disadvantaged Adolescents., Lorna Burke, Dr. Hannah Goss, Craig Smith, Dr. Johann Issartel, Dr. Sarahjane Belton

SURE Journal: Science Undergraduate Research Experience Journal

Aim: LifeLab is co-designed by and for Junior Cycle students from social disadvantage in Ireland, with the hope to improve health literacy and subsequent health outcomes in this cohort. The aim of this study was to evaluate the enjoyment levels of students participating in the pilot of LifeLab, with a view to informing future development of the intervention.

Method: As part of the process evaluation of the pilot of LifeLab, a series of focus groups and purposively designed enjoyment scales were completed by 80 adolescents, from one disadvantaged school in Dublin, Ireland. Inductive thematic analysis was carried out to analyse …

The Acute Effects Of Talocrural Mwm Compared With The Application Of Soft-Tissue Of The Plantarfascia On Chronic Lateral Ankle Sprains For Ankle Dorsiflexion R.O.M., Peter Hempenstall, Brian O'Rourke

SURE Journal: Science Undergraduate Research Experience Journal

Previous research has looked at various treatment remedies for improving acute ankle Dorsiflexion Range of Motion (DFROM) post chronic Lateral Ankle Sprain (LAS). Mulligan’s Mobilisation with Movement (MWM) appears frequently however, the significance and mechanism remain quite conflicting (Gilbreath et al., 2015). It is also known that after a LAS, the Lateral Ligament Complex (LLC) is compromised and the calcaneus inverts, increasing stiffness of plantarfascia (Al-Mohrej & Al-Kenani, 2016, Denegar et al., 2002, Loudon & Bell, 1996). The objective of this study was to further explore the effectiveness of MWM compared with soft-tissue (ST) application of the plantarfascia on acute …

Therapies For Mitochondrial Disorders, Kayli Sousa Smyth, Anne Mulvihill

SURE Journal: Science Undergraduate Research Experience Journal

Mitochondria are cytoplasmic, double-membrane organelles that synthesise adenosine triphosphate (ATP). Mitochondria contain their own genome, mitochondrial DNA (mtDNA), which is maternally inherited from the oocyte. Mitochondrial proteins are encoded by either nuclear DNA (nDNA) or mtDNA, and both code for proteins forming the mitochondrial oxidative phosphorylation (OXPHOS) complexes of the respiratory chain. These complexes form a chain that allows the passage of electrons down the electron transport chain (ETC) through a proton motive force, creating ATP from adenosine diphosphate (ADP). This study aims to explore current and prospective therapies for mitochondrial disorders (MTDS). MTDS are clinical syndromes coupled with abnormalities …

Anthelmintic Resistance In Sheep Across Ireland And The Uk: A Literature Review Of The In Vivo Versus In Vitro Methods, Megan Tumulty

SURE Journal: Science Undergraduate Research Experience Journal

Background: The animal welfare and production consequences of gastrointestinal nematode infections, namely Nematodirus battus, on sheep are compelling. The control of gastrointestinal infections has been heavily reliant on the administration of anthelmintics since their introduction into mainstream use in 1960. However, their frequent and often excessive use has resulted in anthelmintic resistance being reported extensively in several gastrointestinal nematode species. The prevalence of anthelmintic resistance as well as the increase in the number of cases of multiple-drug resistance in nematode populations now poses substantial hindrance on the viability of sheep production systems. However, despite the threat N. battus poses …

Call For Papers. Words Into Picturespictures: E. E. Cummings´ Art Across Borders, Jiøí Flajšar, Zénó Vernyik

Spring: The Journal of the E. E. Cummings Society

No abstract provided.

News, Notes, & Correspondence

Spring: The Journal of the E. E. Cummings Society

No abstract provided.