Digital Commons Network^™

The Microbial Etiology Of Community-Acquired Pneumonia In Adults: From Classical Bacteriology To Host Transcriptional Signatures, Naomi J Gadsby, Daniel M Musher

Faculty, Staff and Students Publications

All modern advances notwithstanding, pneumonia remains a common infection with substantial morbidity and mortality. Understanding of the etiology of pneumonia continues to evolve as new techniques enable identification of already known organisms and as new organisms emerge. We now review the etiology of pneumonia (at present often called "community-acquired pneumonia") beginning with classic bacteriologic techniques, which identified Streptococcus pneumoniae as the overwhelmingly common cause, to more modern bacteriologic studies, which emphasize Haemophilus influenzae, Staphylococcus aureus, Moraxella catarrhalis,

The Association Between Adverse Childhood Experiences, Self-Silencing Behaviours And Symptoms In Women With Fibromyalgia., Alison M. Bacon, Leah White

School of Psychology

Poor adult health has consistently been associated with Adverse Childhood Experiences (ACEs). The process is not fully understood but is likely to involve a complex interaction of biological and psychosocial factors. Early life stress can affect the developing brain resulting in long-term hyper-responses to stress and raised inflammatory biomarkers. Women with fibromyalgia syndrome (FMS) frequently report ACEs and also self-sacrificial behaviours whereby they repress their own needs and emotions to preserve personal relationships. This behavioural profile (termed self-silencing) may develop following ACEs but has not previously been considered in the context of FMS. This study examined whether self-silencing mediates the …

Assessing The Influence Of Behavioural Parameterisation On The Dispersal Of Larvae In Marine Systems, M. K. James, J. A. Polton, C. G. Mayorga-Adame, K. L. Howell, A. M. Knights

School of Biological and Marine Sciences

Predicting dispersal and quantifying ecological connectivity are increasingly referenced as fundamental to understanding how biodiversity is structured across space and time. Dispersal models can provide insight, but their predictions are influenced by our capacity to simulate the biology and physics known to influence dispersal. In a marine context, vertical swimming behaviour is considered important in influencing the spatial organisation of species across seascapes, but the mechanisms underpinning these movements remain unresolved, making it unclear how best to incorporate behaviour within models. Here, using a 3-D hydrodynamic model coupled with a Lagrangian particle tracker, we show how different modelled larval behaviours, …

Computer Ergonomics And Computer-Related Illnesses: The Experience Of Library Personnel, Olaide Akinbo, Damilare Andrew Omideyi

Library Philosophy and Practice (e-journal)

The deployment and frequent use of Information and Communication Technologies (ICTs) in carrying out library tasks had long been leading to computer-related illnesses among library personnel especially in academic libraries. The designing of computer ergonomics in most academic libraries were observed to be affecting the wellbeing and productivity of library personnel. This study was carried out to investigate computer ergonomics and computer-related illnesses: the experience of library personnel.

The study adopted the survey research design with a study population of 60 library personnel in University of Lagos (UNILAG) and Michael Otedola College of Primary Education (MOCPED) libraries, Lagos State, …

Influence Of Reading Habit On Perception And Use Of Reference Sources By Postgraduate Students In The Faculty Of Education Of Ibadan, Nigeria, Sunday A. Oluwaniyi, Lawrence Akingbade

Library Philosophy and Practice (e-journal)

Abstract

Libraries play a critical role in promoting reading habits. If postgraduate students cultivate the habits of reading, their perception and use of reference sources will be enhanced. The main objective is to determine the influence of reading habits on the perception and use of reference sources by postgraduates in the Faculty of Education, University of Ibadan. Descriptive survey research design was adopted for the study and the study population consisted of 2503 postgraduate students of the Faculty of Education, University of Ibadan, Nigeria, Stratified random sampling technique was used to select the sample size of 337 and tie questionnaire …

Expanded Proteomic Survey Of The Human Parasite Leishmania Major Focusing On Changes In Null Mutants Of The Golgi Gdp-Mannose/Fucose/Arabinopyranose Transporter, Gloria Polanco, Nichollas E Scott, Lon F Lye, Stephen M Beverley

2020-Current year OA Pubs

The trypanosomatid protozoan parasite

A Mobile Phone Text Messaging Intervention To Manage Fatigue For People With Multiple Sclerosis, Spinal Cord Injury, And Stroke: Development And Usability Testing, Kerri A. Morgan, Alex W K Wong, Kim Walker, Rachel Heeb Desai, Tina M Knepper, Pamela K Newland

2020-Current year OA Pubs

BACKGROUND: Fatigue significantly affects daily functioning in persons with disabilities. Fatigue management can be challenging, and the information provided during routine physician visits to manage fatigue can be overwhelming. One way to address fatigue is to increase knowledge, skills, and confidence for self-management (ie, patient activation). Self-management programs have shown promising effects in targeting fatigue in persons with disabilities. However, satisfaction with self-management programs is low for persons with disabilities, and tailoring interventions to personalized needs has been recommended. SMS text messaging is increasingly being used to implement health behavior change interventions in a person's natural environment. Little has been …

Advice To Clinicians On Communication From Adolescents And Young Adults With Cancer And Parents Of Children With Cancer, Meghana Srinivas, Erica C Kaye, Lindsay J Blazin, Justin N Baker, Jennifer W Mack, James M Dubois, Bryan A Sisk

2020-Current year OA Pubs

Effective communication is integral to patient and family-centered care in pediatric and adolescent and young adult (AYA) oncology and improving healthcare delivery and outcomes. There is limited knowledge about whether AYAs and parents have similar communication preferences and needs. By eliciting and comparing communication advice from AYAs and parents, we can identify salient guidance for how clinicians can better communicate. We performed secondary analysis of semi-structured interviews from 2 qualitative communication studies. In one study, 80 parents of children with cancer during treatment, survivorship, or bereavement were interviewed. In the second study, AYAs with cancer during treatment or survivorship were …

Migrant Visits Over Time: Ethnographic Returning And The Technological Turn, Loretta Baldassar

Research outputs 2022 to 2026

This paper reflects on four decades of research (via ethnographic returning) to explore the social transformations in travel and communication technologies that have impacted the lived experiences, and consequently the theoretical conceptualization, of migrant visits. A comparison of migration waves between Italy and Australia reveals both continuities in visiting experience as deeply relational practices that facilitate a mutuality of being, but also transformations brought about by the technological turn. Visits take on different meanings depending on individual/ family life stage, generation, and community and national histories. The capacity for both physical and virtual copresence must be understood as coconstitutive, requiring …

Utilization Of Cardiovascular Magnetic Resonance (Cmr) Imaging For Resumption Of Athletic Activities Following Covid-19 Infection: An Expert Consensus Document On Behalf Of The American Heart Association Council On Cardiovascular Radiology And Intervention (Cvri) Leadership And Endorsed By The Society For Cardiovascular Magnetic Resonance (Scmr), Frederick L. Ruberg, Aaron L. Baggish, Allison G. Hays, Michael Jerosch-Herold, Jiwon Kim, Karen G. Ordovas, Gautham Reddy, Chetan Shenoy, Jonathan W. Weinsaft, Pamela K. Woodard

2020-Current year OA Pubs

The global pandemic of coronavirus disease 2019 (COVID-19) caused by infection with severe acute respiratory suyndrome coronavirus 2 (SARS-CoV-2) is now entering its 4th year with little evidence of abatement. As of December 2022, the World Health Organization Coronavirus (COVID-19) Dashboard reported 643 million cumulative confirmed cases of COVID-19 worldwide and 98 million in the United States alone as the country with the highest number of cases. While pneumonia with lung injury has been the manifestation of COVID-19 principally responsible for morbidity and mortality, myocardial inflammation and systolic dysfunction though uncommon are well-recognized features that also associate with adverse prognosis. …

Utilization Of Cardiovascular Magnetic Resonance (Cmr) Imaging For Resumption Of Athletic Activities Following Covid-19 Infection: An Expert Consensus Document On Behalf Of The American Heart Association Council On Cardiovascular Radiology And Intervention (Cvri) Leadership And Endorsed By The Society For Cardiovascular Magnetic Resonance (Scmr), Frederick L Ruberg, Aaron L Baggish, Allison G Hays, Michael Jerosch-Herold, Jiwon Kim, Karen G Ordovas, Gautham Reddy, Chetan Shenoy, Jonathan W Weinsaft, Pamela K Woodard

2020-Current year OA Pubs

The global pandemic of coronavirus disease 2019 (COVID-19) caused by infection with severe acute respiratory suyndrome coronavirus 2 (SARS-CoV-2) is now entering its 4th year with little evidence of abatement. As of December 2022, the World Health Organization Coronavirus (COVID-19) Dashboard reported 643 million cumulative confirmed cases of COVID-19 worldwide and 98 million in the United States alone as the country with the highest number of cases. While pneumonia with lung injury has been the manifestation of COVID-19 principally responsible for morbidity and mortality, myocardial inflammation and systolic dysfunction though uncommon are well-recognized features that also associate with adverse prognosis. …

Antibodies Targeting The Neuraminidase Active Site Inhibit Influenza H3n2 Viruses With An S245n Glycosylation Site, Daniel Stadlbauer, Ali H Ellebedy, Et Al.

2020-Current year OA Pubs

Contemporary influenza A H3N2 viruses circulating since 2016 have acquired a glycosylation site in the neuraminidase in close proximity to the enzymatic active site. Here, we investigate if this S245N glycosylation site, as a result of antigenic evolution, can impact binding and function of human monoclonal antibodies that target the conserved active site. While we find that a reduction in the inhibitory ability of neuraminidase active site binders is measurable, this class of broadly reactive monoclonal antibodies maintains protective efficacy in vivo.

Fetal Brain Tumors, A Challenge In Prenatal Diagnosis, Counselling, And Therapy, Ivonne Alexandra Bedei, Thierry A G M Huisman, William Whitehead, Roland Axt-Fliedner, Michael Belfort, Magdalena Sanz Cortes

Faculty, Staff and Students Publications

Fetal brain tumors are a rare entity with an overall guarded prognosis. About 10% of congenital brain tumors are diagnosed during fetal life. They differ from the postnatally encountered pediatric brain tumors with respect to location and tumor type. Fetal brain tumors can be benign or malignant and infiltrate or displace adjacent brain structures. Due to their high mitotic rate, they can show rapid growth. Outcome depends on age of diagnosis, size, and histological tumor type. Findings like polyhydramnios and macrocephaly encountered on routine ultrasound are frequently associated. Detailed prenatal anomaly scan and subsequent fetal magnetic resonance imaging (MRI) may …

Sodium Content And Labelling Of Packaged Foods And Beverages In Nigeria: A Cross-Sectional Study, Adedayo E Ojo, Mark D Huffman, Et Al.

2020-Current year OA Pubs

Increased consumption of unhealthy processed foods, particularly those high in sodium, is a major risk factor for cardiovascular diseases. The nutrition information on packaged foods can help guide consumers toward products with less sodium and support government actions to improve the healthiness of the food supply. The aims of this study were to estimate the proportion of packaged foods displaying nutrition information for sodium and other nutrients specified by Nigerian nutrition labelling regulations and to determine the amount of sodium in packaged foods sold in Nigeria using data from the nutritional information panel. Data were collected from November 2020 to …

Impact Of Cd4 T Cells On Intratumoral Cd8 T-Cell Exhaustion And Responsiveness To Pd-1 Blockade Therapy In Mouse Brain Tumors, Saad M. Khan, Rupen Desai, Andrew Coxon, Alexandra Livingstone, Gavin P Dunn, Allegra Petti, Tanner M Johanns

2020-Current year OA Pubs

BACKGROUND: Glioblastoma is a fatal disease despite aggressive multimodal therapy. PD-1 blockade, a therapy that reinvigorates hypofunctional exhausted CD8 T cells (T

METHODS: Single-cell RNA sequencing was performed on flow sorted tumor-infiltrating lymphocytes from female C57/BL6 mice implanted with each model, with and without PD-1 blockade therapy. CD8

RESULTS: The CD8 T-cell compartment of the models is composed of heterogenous CD8 T

CONCLUSIONS: Here, we describe that dysfunctional CD4 T cells are associated with terminal CD8 T-cell exhaustion, suggesting CD4 T cells impact PD-1 blockade efficacy by controlling the severity of exhaustion. Given that CD4 lymphopenia is frequently observed in …

A Genome-Wide Association Study Of 2304 Extreme Longevity Cases Identifies Novel Longevity Variants, Harold Bae, Ping An, Mary Feitosa, Et Al.

2020-Current year OA Pubs

We performed a genome-wide association study (GWAS) of human extreme longevity (EL), defined as surviving past the 99th survival percentile, by aggregating data from four centenarian studies. The combined data included 2304 EL cases and 5879 controls. The analysis identified a locus in CDKN2B-AS1 (rs6475609,

Full Step Z-Resolution Printing, Sanne Marx

Defensive Publications Series

This publication relates to an FFF 3D printer generating an interface layer between a raft and the print itself to increase dimensional accuracy, such that subsequent motion paths all conform to the full step resolution of the printers Z-axes.

A Guide For Our Times: Herbert Hoover's Critique Of Supreme Court Expansion, Matthew Chopp

Compass: An Undergraduate Journal of American Political Ideas

Former President Herbert Hoover’s critiques of FDR’s plan to expand the Supreme Court are useful for defending against contemporary calls to enlarge the composition of the Court, such as the Judiciary Act of 2021.

Critique Of Hayek's Liberalism And The Rule Of Law, Kacper Mykietyn

Compass: An Undergraduate Journal of American Political Ideas

In this paper, I raise a few doubts about the adequacy of Hayek's liberal theory and the rule of law in the twenty-first century. I argue that the theory 1) fails to be morally neutral by not giving proper attention to the harm experienced by the minorities, 2) does not acknowledge a satisfactory account for the exploitation of the working class, and 3) operates with a parochial definition of freedom.

Liberating The Truth In Augustine’S Confessions And Douglass’ Narrative, Vincent Hanrahan

Compass: An Undergraduate Journal of American Political Ideas

In this paper, I explore how Frederick Douglass’ and St. Augustine's understanding of the corruption of God's word produced their respective achievement of freedom. In examining Augustine’s Confessions and Douglass’ Narrative, we come to understand the moral imperative of public service both thinkers promoted; the idea that individuals have a distinct social obligation to share their knowledge in a promotion of the greater good.

Review Of "The Secret History Of Rdx: The Super-Explosive That Helped Win World War Ii" By Colin F. Baxter, Alex Souchen

Canadian Military History

Review of The Secret History of RDX: The Super-Explosive that Helped Win World War II by Colin F. Baxter

Review Of "The Empire On The Western Front: The British 62nd And Canadian 4th Divisions In Battle" By Geoffrey Jackson, Bradley Shoebottom

Canadian Military History

Review of The Empire on the Western Front: The British 62nd and Canadian 4th Divisions in Battle by Geoffrey Jackson.

Crossing The Grebbe Line: Canada’S Faustian Bargain To Save Civilians In The Western Netherlands, April-May 1945, Nathan Dyck

Canadian Military History

Beginning at the military-political level and ending at the regimental level, this paper will explore the growth of Canadian responsibility within a failing Allied relief framework throughout the Dutch Hunger Winter 1944-1945. Beginning in early April 1945, I Canadian Corps experienced a growing responsibility to secure an independently negotiated and effective ceasefire on the Grebbe Line to enable transport of food prior to broader German surrender. Under the name of Operation Faust, I Corps utilised targeted medical and food relief practices to address gaps in Allied relief capacity, following what Canadian Military Headquarters (CMHQ) referred to as a “hastily improvised” …

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From The Editor, Brenda Machosky

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An Educator’S Reflection On The Importance Of Embodiment, Imagination, And Liberation, Ashley N. Gibson

Journal of Multicultural Affairs

This reflection piece offers an interpretation of the years 2020-2021, through the earliest days of the COVID-19 pandemic and the racial awakenings in the US. Writing at the intersections of race, gender, and religion, this piece is part essay, part spoken word, and part treatise. The ultimate call to action is threefold; we must lean into embodiment as a habit for living, use our imaginations, and seek liberation for ourselves and one another if we are to hope for a better future. While many aspects of life now seem bleak, there is hope if we consider these three principles for …

Black Mother Scholars Matter: Navigating Anti-Black Educational Spaces For Our Black Boys, Pricella Morris, Monique Matute-Chavarria

Journal of Multicultural Affairs

This article draws from Black Critical Theory to explain how two mother scholars advocated for their Black sons in an anti-black education system. Additionally, the article focuses on antiblackness to describe the social suffering and resistance through ideologies and educational practices our children experienced at the hands of teachers and teaching staff in private and public schools. The first story details the experience of racism and teacher bias of a typically developing Black child. The second story details the inequitable and racist experiences of a Black boy with autism. Each of these experiences highlight the importance of advocating for Black …

A Content Analysis Of Educators’ Perceptions Of Anti-Black Bias: Implications For Black Students, Monica R. Brown

Journal of Multicultural Affairs

Recent research and scholarship have highlighted anti-Black bias in today’s schools. This study explored the perceptions that in-service educators had regarding the ways anti-Black bias is represented in schools. This basic qualitative study included one open-ended question that investigated school personnel’s perspectives regarding how anti-Black bias is represented in the schools. A qualitative content analysis was performed on the open-ended question. Participants included 18 in-service educators enrolled in a summer multicultural special education course that is a required course in the department’s special education master’s program. Results from the content analysis yielded 47 unique statements from 18 responses. From the …

Unlocking Passion And Setting Students Free: The Impact Of Culturally Relevant Writing Instruction In A Middle School English I Classroom, Adam Whitaker, Trina J. Davis, Mónica V. Neshyba

Journal of Multicultural Affairs

Culturally relevant writing instruction has the potential to validate the voices of students often not heard. Documented disparities in student writing proficiency in grades K-12 indicate a pressing need to employ more effective approaches in facilitating writing instruction. This paper presents the findings of a mixed methods research study that explored eighth grade English I students’ middle school reading and writing preferences, writing experiences, and the impact of culturally relevant writing instruction. Data were gathered from 63 students via reflective journals, writing interest forms, learning logs, and writing artifacts collected throughout a 3-week writing unit. Our findings reveal that writing …

Poetry And Praxis: Lessons From An Activist Educator, Dr. Emmanuel Tabi

Journal of Multicultural Affairs

Drawing on data from a narrative multi-case study based in Toronto, Canada, this article discusses the lived experiences of one Black activist. Utilizing critical race theory, new literacy studies and the rhetoric of cultural production as theoretical frameworks, the article foregrounds the work of Ebele, a Toronto activist whose work supported the educational trajectories and emotional well-being of Black students, many of whom reported being marginalized in school. Through his creative labor, Ebele directly addressed the sociology of anti-Black racism that deeply influences the lives of Afrodiasporic people in Canada. This article continues the conversation about what it means to …