Digital Commons Network^™

Safety And Microbiological Activity Of Phage Therapy In Persons With Cystic Fibrosis Colonized With Pseudomonas Aeruginosa: Study Protocol For A Phase 1b/2, Multicenter, Randomized, Double-Blind, Placebo-Controlled Trial, Pranita D Tamma, Maria Souli, Michael Billard, Joseph Campbell, Douglas Conrad, Damon W Ellison, Beth Evans, Scott R Evans, Kerryl E Greenwood-Quaintance, Andrey A Filippov, Holly S Geres, Toshimitsu Hamasaki, Lauren Komarow, Mikeljon P Nikolich, Thomas P Lodise, Seema U Nayak, Carmelle Norice-Tra, Robin Patel, David Pride, Janie Russell, Daria Van Tyne, Henry F Chambers, Vance G Fowlerjr, Robert T Schooley, Antibacterial Resistance Leadership Group

Faculty, Staff and Student Publications

BACKGROUND: Bacteriophages (phages) are a promising anti-infective option for human disease. Major gaps remain in understanding their potential utility.

METHODS: This is a randomized, placebo-controlled, double-blind study of a single dose of intravenous phage in approximately 72 clinically stable adult cystic fibrosis volunteers recruited from up to 20 US sites with Pseudomonas aeruginosa airway colonization. The single dose of phage consists of a mixture of four anti-pseudomonal phages. Six sentinel participants will be sequentially enrolled with dose escalation of the phage mixture by one log

DISCUSSION: This trial will investigate the activity of phages in reducing P. aeruginosa colony counts …

Preparation Of Highly-Cyclized Sulfurized Polyacrylonitrile For Lithium-Sulfur Batteries, Xuan Ji, Jia-Yu Wang, An-Bang Wang, Wei-Kun Wang, Ming Yao, Ya-Qin Huang

Journal of Electrochemistry

Sulfurized polyacrylonitrile (SPAN) is regarded as an attractive cathode candidate of lithium-sulfur (Li-S) batteries for its non-dissolution mechanism and effective alleviation of polysulfides shuttling issue in Li-S batteries, displaying high utilization of cathode active material, outstanding cycle stability and structural stability. However, the relation between cyclization degree and cycle stability of SPAN is still unveiled. In this work, SPAN-C-V composites were synthesized by co-introduction of CuSO₄ and zinc n-ethyl-n-phenyldithiocarbamate (ZDB) in the co-heating of sulfur and polyacrylonitrile. The co-introduction of CuSO₄ and ZDB reduced the cyclization reaction onset temperature of PAN while increased the C—C/C=C within SPAN-C-V, thus …

Carbon-Al Interface Effect On The Performance Of Ionic Liquid-Based Supercapacitor At 3 V And 65 OC, Zhen-Zhen Ye, Shu-Ting Zhang, Xin-Qi Chen, Jin Wang, Ying Jin, Chao-Jie Cui, Lei Zhang, Lu-Ming Qian, Gang Zhang, Wei-Zhong Qian

Journal of Electrochemistry

Ionic liquid (IL) electrolyte-based supercapacitors (SCs) have advantages of high operating voltage window, high energy density and nonflammability, as compared to conventional acetonitrile-based organic electrolyte SCs, and are typically suitable for the large-scale energy storage in the era of carbon neutrality full of renewable, but unstable electricity. However, current efforts were concentrated on the study with coin-cell type of IL-SCs, and less has been reported on the pouch type of IL-SCs for a long cycling time yet. To fabricate a reliable SC for the life time test or for the accelerated aging test under high temperature, one should concern the …

Application Of Artificial Intelligence To Lithium-Ion Battery Research And Development, Zhen-Wei Zhu, Jing-Yi Qiu, Li Wang, Gao-Ping Cao, Xiang-Ming He, Jing Wang, Hao Zhang

Journal of Electrochemistry

Lithium-ion batteries (LIBs) have become one of the best solutions to the energy storage issue in modern society. However, the battery materials and device development are both complex, and involve multivariable problems. Traditional trial-and-error approach, which relies on researchers to conduct experiments, has encountered bottlenecks in the improvement of the battery performance. Artificial intelligence (AI) is the most potential technology to deal with this issue due to its powerful high-speed and capabilities of processing massive data. In particular, the capability of machine learning (ML) algorithms in assessing multidimensional data variables and discovering patterns in the sets are expected to assist …

The Sexual And Gender-Based Violence Epidemic Meets The Covid-19 Pandemic: Survivors’ And Advocates’ Narratives In Egypt, Mozn Hassan, Helen Rizzo

Faculty Journal Articles

This research traces activism over the last 30 years against sexual and gender-based violence with a focus on survivors’ and advocates’ narratives in Egypt. We argue that several focusing events in Egypt and the support of transnational advocacy networks over the last decades have galvanised the efforts of activists and citizens of good will to mobilise around these issues. Egyptian feminist mobilisation during the pandemic brought to the public sphere the untold stories of the forms of violence that occurred through online and social media platforms. While social media and other online tools hold the promise of becoming “a new …

Decadal Time-Series Depletion Of Dissolved Oxygen At Abyssal Depths In The Northeast Pacific, K. L. Smith, M. Messié, T. P. Connolly, C. L. Huffard

Faculty Research, Scholarly, and Creative Activity

Dissolved oxygen depletion in the global ocean is well documented over several decades from the surface ocean to abyssal depths. This decline is especially prevalent in the Northeast Pacific. A significant decline in dissolved oxygen has been measured over 30 years at 4,000–4,100 m depth (Station M) beneath the California Current off central California. Three principal hypotheses examined the relationship of declining oxygen with biological and physical factors over the 30-year time series. Annual resolution revealed Ekman pumping, coastal upwelling, particulate matter flux, and sediment community oxygen consumption having significant correlations with bottom water dissolved oxygen concentration. Coastal upwelling accounted …

Construction Of Tudang Sipulung As A Group Counseling Strategy For Bugis Adolescents In The Perspective Of Kipas Counseling Model, Aswar Aswar, Edil Wijaya Nur, M. Amirullah, Fitriana Fitriana

Jurnal Kajian Bimbingan dan Konseling

The purpose of this article is to describe the existence of Tudang Sipulung for group guidance that used KIPAS Counseling for the Bugis Youth at Senior High School at Sidrap. This research used a qualitative approach with Triple Hermeneutic Analysis method. The data collection technique are Interview and literature studies as well as data validation which is achieved through data triangulation. The subjects of this study were four people, two people from public figure (culturalists) and two people from students (Bugis youth). The results showed that Tudang Sipulung is the ancestral heritage of the Sidrap’s Bugis Society which contains positive …

Human Character Based On Ki Ageng Suryomentaram Teachings And Its Implementation In Guidance And Counseling Services, Bakhrudin All Habsy, Nanda Alfan Kurniawan

Jurnal Kajian Bimbingan dan Konseling

The Indonesian nation as a large nation consisting of various religions, ethnicities, and cultures, of course, deserves to have the aspiration to have a basic human philosophy paradigm based on Indonesian culture based on dialogue between the soul sciences that live in Indonesian human cognition. This study aims to present the concept of basic human philosophy in the teachings of Ki Ageng Suryomentaram. The research method uses Gadamerian hermeneutics in a qualitative approach. The collected data is then analyzed using Parts and Whole analysis and then checked the validity of the data through the stages of credibility, transferability, dependability, and …

Psychological Well-Being And Student Academic Burnout, Henny Indreswari, Devy Probowati, Indriyana Rachmawati

Jurnal Kajian Bimbingan dan Konseling

Psychological well-being is an important aspect for students that needs to be considered in the current situation, which in fact many are faced with academic burnout. This research was conducted with the aim of knowing the relationship between psychological well-being and student academic burnout. The research design used is correlation, with a research sample of 180 students. The sampling technique used is proportional random sampling. Collecting data using psychological well-being scale and academic burnout scale. The data analysis technique used is Pearson's product moment. The results showed that psychological well-being has a negative relationship with academic burnout. This means that …

Multi-Electron Reaction-Boosted High Energy Density Batteries: Material And System Innovation, Rui-Qi Guo, Feng Wu, Xin-Ran Wang, Ying Bai, Chuan Wu

Journal of Electrochemistry

The continuous development of the global energy structure transformation has put forward higher demands upon the development of batteries. The improvements of the energy density have become one of the important indicators and hot topic for novel secondary batteries. The energy density of existing lithium-ion battery has encountered a bottleneck due to the limitations of material and systems. Herein, this paper introduces the concept and development of multi-electron reaction materials over the past twenty years. Guided by the multi-electron reaction, light weight electrode and multi-ion effect, current development strategies and future trends of high-energy-density batteries are highlighted from the perspective …

A Lagrangian Particle Model With Nesting Capability And Its Application To The Modeling Of Plastics In The Gulf Of Mexico, Weiyuan Dong

LSU Master's Theses

In our study, we refined an offline three-dimensional (3D) Lagrangian model named the Larval TRANSport Lagrangian (LTRANS) model and applied it to the Gulf of Mexico (GOM). Previous research that applied the model within the Texas-Louisiana (TXLA) shelf domain, which released plastics to simulate their trajectories and fate, showed that more than 40% of simulated particles did not reach the land boundaries. Some of those particles were assumed to move out of the TXLA domain. In reality, these particles could also re-enter the TXLA domain due to processes such as tidal excursion, mesoscale eddies and inertial oscillation. However, the model …

Pharmacokinetic Study Of Intranasal Dexamethasone And Methylprednisolone Compared With Intravenous Administration: Two Open-Label, Single-Dose, Two-Period, Two-Sequence, Cross-Over Study In Healthy Volunteers, Graciela Cárdenas, Raúl J. Bobes, Gladis Fragoso, Nicolas I. Pérez-Osorio, Marisela Hernández, Alejandro Espinosa, Agnes Fleury, José Flores, Juan Carlos Alvarenga, Juan Pedro Laclette

School of Medicine Publications

Dexamethasone (DXM) and methylprednisolone (MEP) are potent glucocorticoids used to control several inflammatory conditions. Evidence of delayed DXM reaching the central nervous system (CNS) as well as tachyphylaxis and systemic, undesirable side effects are the main limitations of peripheral delivery. Intranasal administration offers direct access to the brain as it bypasses the blood–brain barrier. The Mucosal Atomization Device is an optimal tool that can achieve rapid absorption into the CNS and the bloodstream across mucosal membranes. This study was designed to evaluate and compare the bioavailability of DXM and MEP after intranasal versus intravenous administration. Two open-label, balanced, randomized, two-treatment, …

Listen To The Voices Of The Women, Judith Mirkinson

Journal of International Women's Studies

Using survivor testimonies, military records and statements from human rights organizations, this paper lays out the undeniable truth of the “comfort women” system. This truth is recognized by the international community and maintains that the Japanese government and Japanese Imperial Army instituted and maintained the largest system of sexual slavery in the 20th century. These testimonies provide the factual counterpoint to the historical denialism of Harvard Professor J. Mark Ramseyer as well as the Japanese government. The “comfort women” survivors’ experiences, since breaking a 40-year silence in the 1990s, manifest a resilience and sense of purpose in demanding an accounting …

Ramseyer’S History Denialism And The Efforts To “Save Ramseyer”: Focusing On Critique Of “A Response To My Critics” (2022), Sung Hyun Kang

Journal of International Women's Studies

This article focuses on Ramseyer’s “Contracting for Sex in the Pacific War: A Response to My Critics.” Ramseyer did not accept critiques that evaluated his claims, logic, and empirical methods for denialism in document analysis as lacking academic integrity and research sincerity. His response is mostly limited to the issue of “contractual structure at the wartime ‘comfort stations,’” and addressing the idea that women were never “forcibly conscripted at gunpoint or hauled away against their will.” He continues to argue that women were not “forcibly conscripted” because they agreed on “indentured servitude” contracts based on “credible commitments,” which represent “choices” …

My Response To Ramseyer’S Effort To Deny The History Of Japanese Military Sexual Slavery, Pyong Gap Min

Journal of International Women's Studies

The main objective of this paper is to critically evaluate as many of Ramseyer’s arguments as possible included in his 2022 paper. It consists of three sections in addition to the introduction and concluding remarks. The first section summarizes the expanded literature that interpreted the “comfort women” system as sexual slavery, judgments, and recommendations to the Japanese government given by scholars, international human rights organizations and the legislative branches of four Western countries. Since Ramseyer published his article denying the “comfort women” system as sexual slavery without introducing this literature, we cannot consider his article as an academic work. The …

Introduction: A Critical Evaluation Of Mark Ramseyer’S Arguments For “Comfort Women” As Voluntary Prostitutes With Labor Contracts, Pyong Gap Min

Journal of International Women's Studies

No abstract provided.

Quality Of Life Changes In Taiwanese Patients With Dentofacial Deformities Undergoing Orthognathic Surgery, Jing Hao Ng, I-Chen Lee, Becky Chiang-Lin Liu, Ellen Wen-Ching Ko

Taiwanese Journal of Orthodontics

Objectives: The evaluation of orthognathic surgery (OgS) is shifting towards a coherent approach for patient care that balances objective clinician-defined measures with patient-centred outcome assessments, including health-related quality of life (QoL). This aim of this study adds to the pool of literature in East Asian subjects by studying the longitudinal QoL changes in Taiwanese patients with dentofacial deformities (DFD) undergoing OgS, using two standardized questionnaires at three different treatment stages. Materials and Methods: This prospective cohort study comprised 113 consecutive Taiwanese OgS patients who underwent surgical-orthodontic treatment between 2015 and 2018. The subjects completed SF-36 and OHIP-14 standardized questionnaires with …

Erratum: “The Nanograv 12.5yr Data Set: Polarimetry And Faraday Rotation Measures From Observations Of Millisecond Pulsars With The Green Bank Telescope” (Astrophysical Journal (2022) 926:2 (168) Doi: 10.3847/1538-4357/Ac4045), H. M. Wahl, M. A. Mclaughlin, P. A. Gentile, M. L. Jones, R. Spiewak, Z. Arzoumanian, K. Crowter, P. B. Demorest, M. E. Decesar, T. Dolch, J. A. Ellis, R. D. Ferdman, E. C. Ferrara, E. Fonseca, N. Garver-Daniels, G. Jones, M. T. Lam, L. Levin, N. Lewandowska, D. R. Lorimer, R. S. Lynch, D. R. Madison

Pacific Faculty Work

The polarization fractions in Table 3 are incorrect due to errors in the PSRCHIVE pdv routine used to originally calculate the fractions. A more accurate code (the PSRCHIVE psrstat routine) has been implemented for the calculation of the new fractions.

Prostate Cancer Malignancy Detection And Localization From Mpmri Using Auto-Deep Learning As One Step Closer To Clinical Utilization, Weiwei Zong, Eric Carver, Simeng Zhu, Eric Schaff, Daniel Chapman, Joon K. Lee, Hassan Bagher-Ebadian, Benjamin Movsas, Winston Wen, Tarik Alafif, Xiangyun Zong

Radiation Oncology Articles

Automatic diagnosis of malignant prostate cancer patients from mpMRI has been studied heavily in the past years. Model interpretation and domain drift have been the main road blocks for clinical utilization. As an extension from our previous work we trained on a public cohort with 201 patients and the cropped 2.5D slices of the prostate glands were used as the input, and the optimal model were searched in the model space using autoKeras. As an innovative move, peripheral zone (PZ) and central gland (CG) were trained and tested separately, the PZ detector and CG detector were demonstrated effective in highlighting …

Sr Flip-Flop Based Physical Unclonable Functions For Hardware Security, Srinivas Katkoori, Rohith Prasad Challa, Sheikh Ariful Islam

USF Patents

The present disclosure presents various systems and methods for implementing a physical unclonable function device. One such method comprises providing an integrated circuit having a plurality of set/reset flip flop logic circuits, wherein each of the set/reset flip flop logic circuits enters a metastable state for a particular input sequence. The method includes varying circuit parameters for each of the plurality of set/reset flip flop logic circuits to account for manufacturing variations in the set/reset flip flop logic circuits and enable generating a stable but random output in response to the particular input sequence. Thus, by applying the particular input …

Modified Ube3a Gene For A Gene Therapy Approach For Angelman Syndrome, Kevin Ron Nash, Edwin John Weeber, Jennifer Leigh Daily

USF Patents

Angelman Syndrome (AS) is a genetic disorder occurring in approximately one in every 15,000 births. It is characterized by severe mental retardation, seizures, difficulty speaking and ataxia. The gene responsible for AS was discovered to be UBE3A and encodes for E6-AP, an ubiquitin ligase. A unique feature of this gene is that it undergoes maternal imprinting in a neuron-specific manner. In the majority of AS cases, there is a mutation or deletion in the maternally inherited UBE3A gene, although other cases are the result of uniparental disomy or mismethylation of the maternal gene. While most human disorders characterized by severe …

Leadership Doctorates Newsletter: Volume 8, Number 4, Larry Starr, Phd

Leadership Doctorates Newsletter (Formerly Strategic Leadership Newsletter)

In this Issue:

• Congratulations to Dr. Andrew Braverman and Dr. Michael Jones
• Complex and Strategic Leaders who have Graduated with DMgt or PhD Degree
• Emerging Complex and Strategic Leaders Working Toward Degree Completion
• Updated Doctoral Candidate Status
• Our New Home is the School of Business in the College of Design, Engineering and Commerce About the
• Academic Appointments Update: Larry Starr
• Strategic Leadership and Complex Systems Leadership Alumni
• Alumni Profiles : Reverend Dr. Valerie Andrews
• Research Project: Reverend Dr. Valerie Andrews
• Research Project: Carol Haines
• Congratulations to Derek Hunsberger

Homoeopathy In Plantar Psoriasis: An Evidence-Based Case Report, Gr Kiranmayee Rompicherla, Hima Bindu Ponnam

Indian Journal of Research in Homoeopathy

Introduction: Plantar psoriasis is a variant of psoriasis and accounts for 3–4% of total cases of psoriasis. Psoriasis, an autoimmune and chronic inflammatory disease of the skin, can leave the patient in agony with its distressing infection episodes. The homoeopathic system of medicine offers a wide range of medicines that can have a beneficial role in managing cases of psoriasis as depicted in the previous studies. Case summary: A distinct case of plantar psoriasis treated with homoeopathic remedies of ultra-high dilution has been presented here. The evidence-based illustrations were done before and after the treatment and the periodical objective …

Homoeopathic Treatment Of A Diabetic Covid-19 Patient With The Complication Of Bronchitis And Pleural Effusion - A Case Report, Alok Ghosh, Sadia Kamal

Indian Journal of Research in Homoeopathy

Introduction: COVID-19 is a novel SARS-CoV-2 disease that has caused a worldwide pandemic. It is highly contagious and produces severe acute respiratory syndrome. Many homoeopathic medicines have been suggested for treatment of COVID cases and reports have also been published. Case Summary: The present case report is of a 61-year-old COVID-positive, male, presenting with complications such as bronchitis and pleural effusion. He was treated for COVID-19 with a suitable homoeopathic medicine, based on the totality of symptoms, while the patient continued his regular regime of conventional medicine for diabetes mellitus and hypertension. The indicated remedy led to immediate relief …

Do Academic Supervisors Know What Their Employees Want From Work?, Emily Faulconer, John Griffith

Publications

This research has meaning to higher education learning institutions regarding faculty and staff motivation. Effectively motivating employees has captivated management theorists in search of higher morale and higher productivity. This study challenges the assumption by Hersey and Blanchard (1993) based on Lindahl’s (1949) study that supervisors do not know what their employees want from work.

Scope Of Homoeopathy In The Treatment Of Depression: A Narrative Synthesis, Karunakara Moorthi, Radhika P, Manu Chandran, K.C. Muraleedharan

Indian Journal of Research in Homoeopathy

Background: Depression is a disorder of major public health importance, in terms of its prevalence and suffering, dysfunction, morbidity and economic burden. Depression is one of the most common conditions for which people seek homoeopathic treatment. Objective: This study is aimed to understand the scope of homoeopathy in depression based on the results of previous studies. Methods: A study was done to evince the scope of homoeopathic medicines in the treatment of depression. Searches were done in both general and specialised databases. The data were collected from peer-reviewed journals published between January 2001 and January 2021. Efforts …

Homeopathic Management Of Reinke’S Edema In A Non-Smoker: A Case Report, Aditya Pareek

Indian Journal of Research in Homoeopathy

Introduction: Reinke’s edema, also known as polypoid degeneration of vocal cords, is a bilateral, symmetrical swelling of the whole of the membranous part of the vocal cords. Surgery has been the mainstay of treatment for Reinke’s edema. Thus, patients are often left with practically no non-invasive treatment option. Case Summary: This is the case of a 40-year-old male, teacher, who presented with hoarseness of voice for 1 year and opted for homeopathic treatment when he was advised surgery. A rapid improvement in the symptoms, as well as significant objective improvement as confirmed with video laryngoscopy. The results were …

The 2016 Presidential Election Of Donald Trump And Its Impact On The College-Going Experience For Then-Undergraduate Lgbtq+ Students, Nicholas Russo

Seton Hall University Dissertations and Theses (ETDs)

On November 8, 2016, businessman and mogul Donald J. Trump won the U.S. presidential election, sending shockwaves across the country given that polls indicated that Secretary of State Hillary Rodham Clinton would win the election. On U.S. college campuses, students reacted to the election win, and for LGBTQ+ undergraduate students, their marginalized identity was negatively impacted by Trump’s win because of his rhetoric towards this population. Colleges and universities responded to the 2016 election results by sending out communications to affirm their mission and values for all their constituents, but this response was perceived as not supporting by LGBTQ+ undergraduate …

Natural Selection Of Immune And Metabolic Genes Associated With Health In Two Lowland Bolivian Populations, Amanda J. Lea, Angela Garcia, Jesusa Arevalo, Julien F. Ayroles, Kenneth Buetow, Steve W. Cole, Daniel Eid Rodriguez, Maguin Gutierrez, Heather M. Highland, Paul L. Hooper, Anne Justice, Thomas Kraft, Kari E. North, Jonathan Stieglitz, Hillard Kaplan, Benjamin C. Trumble, Michael Gurven

ESI Publications

A growing body of work has addressed human adaptations to diverse environments using genomic data, but few studies have connected putatively selected alleles to phenotypes, much less among underrepresented populations such as Amerindians. Studies of natural selection and genotype–phenotype relationships in underrepresented populations hold potential to uncover previously undescribed loci underlying evolutionarily and biomedically relevant traits. Here, we worked with the Tsimane and the Moseten, two Amerindian populations inhabiting the Bolivian lowlands. We focused most intensively on the Tsimane, because long-term anthropological work with this group has shown that they have a high burden of both macro and microparasites, as …

2022 Draft Final Butte Reduction Works (Brw) Smelter Area Mine Waste Remediation And Contaminated Groundwater Hydraulic Control Site Organic Pollutant Surface Water Sampling Quality Assurance Project Plan (Qapp), Pioneer Technical Services, Inc.

Silver Bow Creek/Butte Area Superfund Site

No abstract provided.