Digital Commons Network^™

Speech Fluency Changes Following Deep Brain Stimulation Of The Subthalamic Nucleus In Parkinson’S Disease: A Meta-Analysis, Emily Morphis

Electronic Theses and Dissertations

Purpose: Speech fluency changes following deep brain stimulation are one aspect that is crucial to consider when exploring treatments for Parkinson’s disease. Deep brain stimulation, specifically of the subthalamic nucleus, has been linked to a decrease in speech fluency despite improved bodily motor control. This acquired dysfluency is referred to as “neurogenic stuttering.” The purpose of the current study is to determine the incidence and severity of speech fluency decline following deep brain stimulation in patients with Parkinson’s disease. A meta-analysis was conducted with 7 studies (239 subjects) that recorded changes in speech fluency. All studies used a quantitative assessment, …

Role Of Astrocytic Insulin-Like Growth Factor 1 In The Regulation Of Behavior, Cognition, And Neuroinflammation, Brayden Thomas

Electronic Theses and Dissertations

Modern medicine has consistently extended life expectancy over recent decades and centuries. Despite this, age-associated cognitive decline and risk of neurodegenerative disease grow in parallel with lifespan, meaning the capacity to live healthier has not mirrored that to live longer. Many studies in both human and rodents have shown the association between age-related cognitive impairment and reduction of insulin-like growth factor-1 (IGF-1) signaling. Additional research has indicated that dysregulated IGF-1 signaling, either systemic or local to the central nervous system (CNS) in cells like neurons and glia, leads to impaired spatial learning and memory in mice. Glia, or glial cells, …

Using Adaptive-Choice Based Conjoint Analysis To Explore Attributes Important In Performance For Division 1 College Football Players, Michaela Marie Slatniske

Electronic Theses and Dissertations

Interdisciplinary teams are essential in the care of collegiate athletes. However, interdisciplinary teams may be composed of members who place utility in key athletic attributes differently. To better understand the differences in utilities various members place on athletic attributes, this study explored the relative importance of attributes in wide receivers (WR), and part-worth utilizes among levels of an attribute through an Adaptive Choice Based Conjoint (ACBC) study. Interdisciplinary team member involved in the care of college football players, including athletic trainers (ATs), ball coaches (BCs), strength and conditioning coaches (S&C), and sports dietitians (SN) were identified from 131 D1 collegiate …

Prenatal Exposure To Methamphetamine Causes Vascular Dysfunction In Adult Male Offspring, Hasitha Chavva, Adam M. Belcher, Daniel A. Brazeau, Boyd Rorabaugh

Pharmaceutical Science and Research

Methamphetamine use during pregnancy can have negative consequences on the offspring. However, most studies investigating the impact of prenatal exposure to methamphetamine have focused on behavioral and neurological outcomes. Relatively little is known regarding the impact of prenatal methamphetamine on the adult cardiovascular system. This study investigated the impact of chronic fetal exposure to methamphetamine on vascular function in adult offspring. Pregnant female rats received daily saline or methamphetamine (5 mg/kg) injections starting on gestational day 1 and continuing until the pups were born. Vascular function was assessed in 5 month old offspring. Prenatal methamphetamine significantly decreased both the efficacy …

Carbon-Sensitive Pedotransfer Functions For Plant Available Water, Dianna K. Bagnall, Cristine L.S. Morgan, Michael Cope, Gregory M. Bean, Shannon Cappellazzi, Kelsey Greub, Daniel Liptzin, Charlotte L. Norris, Elizabeth Rieke, Paul Tracy, Ezra Aberle, Amanda Ashworth, Oscar Bañuelos Tavarez, Andy Bary, R. Louis Baumhardt, Alberto Borbón Gracia, Daniel Brainard, Jameson Brennan, Dolores Briones Reyes, Darren Bruhjell, Cameron Carlyle, James Crawford, Cody Creech, Steven Culman, William Deen, Curtis Dell, Justin Derner, Thomas Ducey, Sjoerd Willem Duiker, Miles Dyck, Benjamin Ellert, Martin Entz, Avelino Espinosa Solorio, Steven J. Fonte, Simon Fonteyne, Ann Marie Fortuna, Jamie Foster, Lisa Fultz, Audrey V. Gamble, Charles Geddes

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Currently accepted pedotransfer functions show negligible effect of management-induced changes to soil organic carbon (SOC) on plant available water holding capacity (θAWHC), while some studies show the ability to substantially increase θAWHC through management. The Soil Health Institute's North America Project to Evaluate Soil Health Measurements measured water content at field capacity using intact soil cores across 124 long-term research sites that contained increases in SOC as a result of management treatments such as reduced tillage and cover cropping. Pedotransfer functions were created for volumetric water content at field capacity (θFC) and permanent wilting point (θPWP). New pedotransfer functions had …

Impact Of Harvest On Switchgrass Leaf Microbial Communities, Esther Singer, Elizabeth M. Carpenter, Jason Bonnette, Tanja Woyke, Thomas E. Juenger

United States Department of Agriculture-Agricultural Research Service / University of Nebraska-Lincoln: Faculty Publications

Switchgrass is a promising feedstock for biofuel production, with potential for leveraging its native microbial community to increase productivity and resilience to environmental stress. Here, we characterized the bacterial, archaeal and fungal diversity of the leaf microbial community associated with four switchgrass (Panicum virgatum) genotypes, subjected to two harvest treatments (annual harvest and unharvested control), and two fertilization levels (fertilized and unfertilized control), based on 16S rRNA gene and internal transcribed spacer (ITS) region amplicon sequencing. Leaf surface and leaf endosphere bacterial communities were significantly different with Alphaproteobacteria enriched in the leaf surface and Gammaproteobacteria and Bacilli enriched in the …

A Rare Presentation Of Acute Acalculous Cholecystitis In A Patient With Acute Hepatitis A, Oseyime Okoeguale, Rafik Elbeblawy, Jimmy Molyneux, Roger Smalligan

UAB Huntsville Research Day - All Presentations

2022 clinical vignette poster

Metabolic Syndrome In A Case Of Acute Intermittent Porphyria (Aip), Rafik Elbeblawy

UAB Huntsville Research Day - All Presentations

2022 oral presentation

Cultivation Of Industrial Hemp On And Near Airports: Implications For Wildlife Use And Risk To Aviation Safety, Bradley F. Blackwell, Page E. Klug, Lee A. Humberg, Zachary T. Brym, Bryan M. Kluever, Jenna Edwards

United States Department of Agriculture Wildlife Services: Staff Publications

Industrial hemp (Cannabis sativa L.; hemp) is an emerging crop in the United States with little known about bird use or the potential for birds to become an agricultural pest. We identified birds associated with hemp fields, using repeated visits to oilseed plots in North Dakota, USA (n = 6) and cannabinoid (CBD) plots in Florida, USA (n = 4) from August to November 2020. We did not control for plot area or density; our observations were descriptive only. We observed 10 species in hemp, 12 species flying over hemp, and 11 species both foraging in and …

Industrial Hemp As A Resource For Birds In Agroecosystems: Human-Wildlife Conflict Or Conservation Opportunity?, Emily A. Kotten, Iona Hennessy, Bryan M. Kluever, Bradley F. Blackwell, Lee A. Humberg, Page E. Klug

United States Department of Agriculture Wildlife Services: Staff Publications

Industrial hemp (Cannabis sativa L.; hemp) is an emerging crop in the United States with little known about bird use or the potential for birds to become an agricultural pest. We identified birds associated with hemp fields, using repeated visits to oilseed plots in North Dakota, USA (n = 6) and cannabinoid (CBD) plots in Florida, USA (n = 4) from August to November 2020. We did not control for plot area or density; our observations were descriptive only. We observed 10 species in hemp, 12 species flying over hemp, and 11 species both foraging in and …

Differentiating The Effects Of Two Non-Native Fish In The Turnbull National Wildlife Refuge, Sarah Richardson

EWU Masters Thesis Collection

This study seeks to determine the individual effects of two non-native fish, the brook stickleback, Culaea inconstans, and pumpkinseed, Lepomis gibbosus, on the aquatic invertebrates and food webs of Turnbull National Wildlife Refuge (TNWR). Ten ponds were analyzed and compared with stable isotope analysis and invertebrate abundance data. Three ponds were chosen to represent each of the following categories: fishless, brook stickleback invaded (BS), and coinvaded, along with a single pumpkinseed (PS) pond. Overall, δ[superscript]13C and δ[superscript]15N values increased in invaded ponds, indicating shifts in the zooplankton community structure and the carbon source of predatory invertebrates. Mean δ[superscript]13C was the …

Collegiate Male Athlete Attitudes Towards Male And Female Strength And Conditioning Coaches: Is There A Role For Motivation?, Shealene J. Little

EWU Masters Thesis Collection

No abstract provided.

Spanish-Speaking Caregivers’ Use Of Referential Labels With Toddlers Is A Better Predictor Of Later Vocabulary Than Their Use Of Referential Gestures, Janet Y. Bang, Manuel Bohn, Joel Ramírez, Virginia A. Marchman, Anne Fernald

Faculty Research, Scholarly, and Creative Activity

Variation in how frequently caregivers engage with their children is associated with variation in children's later language outcomes. One explanation for this link is that caregivers use both verbal behaviors, such as labels, and non-verbal behaviors, such as gestures, to help children establish reference to objects or events in the world. However, few studies have directly explored whether language outcomes are more strongly associated with referential behaviors that are expressed verbally, such as labels, or non-verbally, such as gestures, or whether both are equally predictive. Here, we observed caregivers from 42 Spanish-speaking families in the US engage with their 18-month-old …

Blackcurrants: A Nutrient-Rich Source For The Development Of Functional Foods For Improved Athletic Performance, Ali Ali Redha, Shahida Anusha Siddiqui, Reza Zare, Daniele Spadaccini, Silvia Guazzotti, Xi Feng, Nur Alim Bahmid, Yuan Seng Wu, Fathima Zahraa Ozeer, Rotimi E. Aluko

Faculty Research, Scholarly, and Creative Activity

Blackcurrants are nutrient-rich fruits with a significant amount of bioactive compounds including vitamin C and polyphenols, especially anthocyanins. The high phytochemical content of blackcurrants promotes this fruit to become a valuable functional food ingredient with varying health-promoting activities targeting different consumers including athletes. Athletes experience oxidative stress during intense exercise, which can result in inflammation and reduced exercise performance. Antioxidants such as vitamin C and polyphenols can restore the regular oxidative status of the body. Blackcurrant supplementation has shown potential ergogenic activity to improve athlete performance during high-intensity training. Clinical trials have evaluated the effectiveness of blackcurrant supplementation on exercise …

Novel Molecular Approaches To Diagnostic And Epidemiological Analyses Of Cryptosporidiumspp.Implicated In Clinical Infection, Jennifer K. O'Leary

Theses

Cryptosporidium remains an underestimated, yet highly prevalent, parasitic agent of gastrointestinal illness worldwide. In clinical settings, diagnosis has previously relied on microscopic techniques. However, enteric parasite targeting molecular tools, such as real-time PCR panels, have superseded microscopy in recent years. This body of work examines the nature, implications and opportunities of this paradigm shift. This thesis is divided into seven chapters that consist of a literature review chapter, five experimental chapters focusing on the molecular diagnosis and epidemiological analysis of Cryptosporidium spp., and a final summary chapter. Chapter I provides the contextual narrative and supportive reasoning behind the research undertaken …

Racial/Ethnic Variations In Alcohol And Cigarette Use By Pregnancy Status Among 20- To 44-Year-Old Women, Nhanes 2001–2018, Jacqueline M Hirth, Catherine Valadez, Sandra Gonzalez, Alicia Kowalchuk, Judith A Gutierrez, Roger Zoorob

Faculty, Staff and Students Publications

OBJECTIVES: This study examines alcohol consumption and smoking behaviors by pregnancy status and race/ethnicity in order to inform improved interventions designed to assist women of all races to avoid alcohol and tobacco use during pregnancy for their health and to prevent potential fetal exposure.

METHODS: This retrospective secondary data analysis utilized nationally representative National Health and Nutrition Examination Survey data between 2001 and 2018. Smoking and alcohol use were evaluated by race/ethnicity and pregnancy risk. Sexual behavior, reproductive health, and prescription drug use determined pregnancy risk, categorized as low pregnancy risk, at risk of becoming pregnant, and pregnant. Binary and …

Hypermethylation Of Pi3k-Akt Signalling Pathway Genes Is Associated With Human Neural Tube Defects, Tian Tian, Xinyuan Lai, Kuanhui Xiang, Xiao Han, Shengju Yin, Robert M Cabrera, John W Steele, Yunping Lei, Xuanye Cao, Richard H Finnell, Linlin Wang, Aiguo Ren

Faculty, Staff and Students Publications

Neural tube defects (NTDs) are a group of common and severe congenital malformations. The PI3K-AKT signalling pathway plays a crucial role in the neural tube development. There is limited evidence concerning any possible association between aberrant methylation in PI3K-AKT signalling pathway genes and NTDs. Therefore, we aimed to investigate potential associations between aberrant methylation of PI3K-AKT pathway genes and NTDs. Methylation studies of PI3K-AKT pathway genes utilizing microarray genome-methylation data derived from neural tissues of ten NTD cases and eight non-malformed controls were performed. Targeted DNA methylation analysis was subsequently performed in an independent cohort of 73 NTD cases and …

Inclusion Of Children With Disabilities In Qualitative Health Research: A Scoping Review, Janet Njelesani, Vongai Mlambo, Tsedenia Denekew, Jean Hunleth

2020-Current year OA Pubs

BACKGROUND: Children with disabilities have the right to participate in health research so their priorities, needs, and experiences are included. Health research based primarily on adult report risks misrepresenting children with disabilities and their needs, and contributes to exclusion and a lack of diversity in the experiences being captured. Prioritizing the participation of children with disabilities enhances the relevance, meaningfulness, and impact of research.

METHODS: A scoping review was conducted to critically examine the participation of children with disabilities in qualitative health research. The electronic databases PubMed, PsychInfo, Embase, and Google Scholar were searched. Inclusion criteria included qualitative health studies …

A Nurse-Driven Protocol To Increase Metabolic Screening And Interventions For Inpatients On Antipsychotic Medications, James Thomas Demarco

Yale School of Nursing Digital Theses

Patients on antipsychotic medications are at higher risk of developing metabolic syndrome; nevertheless, metabolic screening for patients on antipsychotics is suboptimal. This project implemented a nurse-driven protocol on inpatient psychiatric units to increase metabolic screening compliance rates. The literature on improving metabolic screening as well as the clinical use of nurse-driven protocols were used to develop a protocol. The initial implementation of the protocol showed no change in screening rate; however, when the protocol was updated to include nursing leader involvement, metabolic screening increased. Nurses’ perception of the nurse-driven protocol was examined and found a negative perception and no change …

Are Pharmacists Up To Speed?: Pharmacy Driven Initiatives, Allison Vargas

All Publications

No abstract provided.

Doctoral Physical Therapy Students' Increased Confidence Following Exploration Of Active Video Gaming Systems In A Problem-Based Learning Curriculum In The United States: A Pre-And Post-Intervention Study, Michelle E. Wormley, Wendy Romney, Diana Veneri, Andrea Oberlander

Physical Therapy Faculty Publications

Purpose: Active video gaming (AVG) is used in physical therapy (PT) to treat individuals with a variety of diagnoses across the lifespan. The literature supports improvements in balance, cardiovascular endurance, and motor control; however, evidence is lacking regarding the implementation of AVG in PT education. This study investigated doctoral physical therapy (DPT) students' confidence following active exploration of AVG systems as a PT intervention in the United States.

Methods: This pretest-posttest study included 60 DPT students in 2017 (Cohort 1) and 55 students in 2018 (Cohort 2) enrolled in a problem-based learning curriculum. AVG systems were embedded into patient cases …

X-Ray Computerized Microtomography And Confocal Raman Microscopy As Complementary Techniques To Conventional Imaging Tools For The Microstructural Characterization Of Cheddar Cheese, Antonio Lourenco, Stephan Handschuh, Mark Fenelon, Laura G. Gómez-Mascaraque

Research Outputs: 2025-Present

This study explored the use of X-ray computerized microtomography (micro-CT) and confocal Raman microscopy to provide complementary information to well-established techniques, such as confocal laser scanning microscopy (CLSM), for the microstructural characterization of cheese. To evaluate the potential of these techniques, 5 commercial Cheddar cheese samples, 3 with different ripening times and 2 with different fat contents, were analyzed. Confocal laser scanning microscopy was particularly useful to describe differences in fat and protein distribution, especially between the 2 samples with different fat contents. The quantitative data obtained through image analysis correlated well with the nutritional information provided in the product …

Thermal Death Kinetics Of Three Representative Salmonella Enterica Strains In Toasted Oats Cereal, Matthew Chick, Antonio Lourenco, Alice Maserati, Ryan C. Fink, Francisco Diez-Gonzalez

Research Outputs: 2025-Present

Several reports have indicated that the thermal tolerance of Salmonella at low-water activity increases significantly, but information on the impact of diverse food matrices is still scarce. The goal of this research was to determine the kinetic parameters (decimal reduction time, D; time required for the first decimal reduction, δ) of thermal resistance of Salmonella in a previously cooked low water activity food. Commercial toasted oats cereal (TOC) was used as the food model, with or without sucrose (25%) addition. TOC samples were inoculated with 10⁸ CFU/mL of a single strain of one of three Salmonella serovars (Agona, Tennessee, …

Twelve Week Calcium Collagen Chelate Or Calcium Plus Vitamin D Supplementation Does Not Affect Bone Metabolism In Trained Cyclists, Beau K. Greer, Christopher Mojock, Bahram Arjmandi, Jeong-Su Kim, Michael Ormsbee, Lynn Panton

Exercise Science Faculty Publications

The purpose of the present study was to determine whether 12 weeks of calcium collagen chelate (CCC) supplementation during habitual training would affect body composition, bone mineral density (BMD), and biomarkers of bone metabolism in competitive cyclists. Twenty trained (maximal aerobic capacity > 50 ml/kg/min, mean training volume: 28 h/wk) male cyclists performed maximal exercise testing and 40-km time trials (TT) on an electronically braked cycle ergometer. BMD of the whole body, lumbar spine (L1-L4), and both hips were measured via dual-energy X-ray absorptiometry (DXA). The cyclists were assigned to one of two groups: 1) 6 g/d of CCC with 600 …

Clean Process To Utilize The Potassium-Containing Phosphorous Rock With Simultaneous Hcl And Kcl Production Via The Steam-Mediated Reactions, Yunshan Wang, Lufang Shi, Houli Li, Yixiao Wang, Zhiying Wang, Xuebin An, Mingzhu Tang, Gang Yang, Jun He, Jing Hu, Yong Sun

Research outputs 2022 to 2026

In this paper, a clean process based on the steam-mediated reactions for simultaneous HCl and KCl production using the potassium (K)-containing phosphorous rock as a precursor is proposed. Through hydrochloric acid (HCl) leaching, not only the generation of H₃PO₄and CaCl₂ (via further precipitation) were realized but also the acid-insoluble residue [phosphorous-rock slag (PS)] rich in elements, that is, K, Al, Si, and so on, in the form of microcline (KAlSi₃O₈) and quartz (SiO₂) was obtained and became readily available for further HCl and KCl generation. Over 95 % of …

Supported Decision-Making: Potential And Challenges For Older Persons, Morgan K. Whitlatch, Rebekah Diller

Articles

In recent years, supported decision-making (SDM) has gained traction as a recognized alternative to guardianship for persons with disabilities in the United States. To date, SDM has not been as widely recognized as an alternative for older people, particularly those struggling with cognitive decline. This paper explores some of the obstacles that have prevented SDM from being used more broadly by older people, identifies ways of surmounting some of those obstacles, and makes recommendations for ways that SDM can be used in the aging context.

Provision Of Non-Invasive Coronary And Carotid Vascular Imaging Results On Changes In Diet And Physical Activity In Asymptomatic Adults: A Scoping Review, Simone Radavelli Bagatini, Abadi K. Gebre, Mary A. Kennedy, Marc Sim, Lauren C. Blekkenhorst, Catherine P. Bondonno, Ben Jackson, James Dimmock, Marcus P. Schlaich, Jonathan M. Hodgson, Joshua R. Lewis

Research outputs 2022 to 2026

Background: Although a healthy diet and physical activity have been shown to prevent or delay cardiovascular disease (CVD) hospitalizations and deaths, most adults do not meet current guidelines. Provision of coronary artery calcification (CAC) and carotid ultrasound (CUS) imaging results may motivate beneficial lifestyle changes. We scoped the existing literature for studies providing non-invasive vascular imaging results and reporting diet, physical activity, and/or anthropometric measures to identify knowledge gaps and opportunities for further research. Methods: A systematic search was performed across three electronic databases, in line with PRISMA ScR guidelines and Arksey and O'Malley's scoping review framework. Results: Twenty studies …

Show, Attend And Detect: Towards Fine-Grained Assessment Of Abdominal Aortic Calcification On Vertebral Fracture Assessment Scans, Syed Zulqarnain Gilani, Naeha Sharif, David Suter, John T. Schousboe, Siobhan Reid, William D. Leslie, Joshua R. Lewis

Research outputs 2022 to 2026

More than 55,000 people world-wide die from Cardiovascular Disease (CVD) each day. Calcification of the abdominal aorta is an established marker of asymptomatic CVD. It can be observed on scans taken for vertebral fracture assessment from Dual Energy X-ray Absorptiometry machines. Assessment of Abdominal Aortic Calcification (AAC) and timely intervention may help to reinforce public health messages around CVD risk factors and improve disease management, reducing the global health burden related to CVDs. Our research addresses this problem by proposing a novel and reliable framework for automated “fine-grained” assessment of AAC. Inspired by the vision-to-language models, our method performs sequential …

Bachelor Of Science In Nursing First Professional Degree & Second Degree Accelerated Student Guide, 2022-2023 Edition, Dr. Susan L. Davis, Rn & Richard J. Henley College Of Nursing

News, Magazines and Reports

The Nursing Student Guide is the official student handbook and provides essential DHCON policies and procedures for academic progression and graduation. This guide is intended to supplement the University Catalog and provide information specific to the nursing programs.

The Law, Economics, And Governance Of Generation Covid-19 Long-Haul, Julia Puaschunder, Martin Gelter

Faculty Scholarship

The SARS-CoV-2 novel coronavirus is an external shock to all societies with lasting impacts that have changed individual, political, and corporate decisions profoundly. Increasing evidence reveals that an estimated 10-50% of those previously infected with COVID-19 face a longer-term or long-term health impact and/or chronic debilitation that in many cases comes and goes in waves. This phenomenon has already been referred to as a pandemic within the pandemic. The broad-based and long-term impact of COVID Long Haulers have also holds the potential to change our world and modern society, lasting through the following three outlined speculative trends: (1) The coronavirus …