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Articles 7591 - 7620 of 10517
Full-Text Articles in Entire DC Network
Public Health Equity Law: Considering Law As A Tool In Achieving Health Equity, Dawn Pepin
Public Health Equity Law: Considering Law As A Tool In Achieving Health Equity, Dawn Pepin
DePaul Law Review
No abstract provided.
Effect Of Cutting Height On Productivity And Quality Of Alfalfa In Northern Area Of Korea, Jong Geun Kim, C. Liu, S. N. Wei, Y. F. Li, E. C. Jeong, H. J. Kim
Effect Of Cutting Height On Productivity And Quality Of Alfalfa In Northern Area Of Korea, Jong Geun Kim, C. Liu, S. N. Wei, Y. F. Li, E. C. Jeong, H. J. Kim
IGC Proceedings (1977-2023)
Alfalfa is a very important forage for livestock feeding. In particular, due to the high crude protein content, it is widely used as a dairy cattle feeds. However, the cultivation of alfalfa is quite limited and main source is imported hay in Korea. There are many reasons, but most importantly, low productivity due to lack of boron in the soil. This experiment was conducted to expand domestic production and use of alfalfa. Alfalfa was sown in the fall of 2018 at 30 kg/ha seeding rate. Alfalfa was harvested four times (3 May, 2 July, 11 September and 13 October) in …
Economic Injury Level For Bermudagrass Stem Maggot (Diptera: Muscidae) In Bermudagrass Forage Production In Texas, V. Corriher-Olson, A. Knutson, F. Mitchell
Economic Injury Level For Bermudagrass Stem Maggot (Diptera: Muscidae) In Bermudagrass Forage Production In Texas, V. Corriher-Olson, A. Knutson, F. Mitchell
IGC Proceedings (1977-2023)
The bermudagrass stem maggot, Atherigona reversura Villeneuve, was first reported damaging bermudagrass Cynodon dactylon (L.) Pers grown for forage in 2010 in the southeastern US. Damage results from individual larvae feeding internally on the vascular tissue just above the terminal node of the grass stem. Damage slows plant growth and reduces forage accumulation. To address the need for economic guidelines to manage this new pest, the relationship between the percent of stems damaged by bermudagrass stem maggot and forage yield was measured in commercial bermudagrass hay fields in northcentral Texas during 2016 and 2017. The slope of the linear regression, …
Diversity And Taxonomic Identity Of Rumen Bacterial Community In Cattle Fed Different Diets, B. K. Korir, J. K. N. Kuria, D. M. Mwangi, M. M. M. Wanyoike
Diversity And Taxonomic Identity Of Rumen Bacterial Community In Cattle Fed Different Diets, B. K. Korir, J. K. N. Kuria, D. M. Mwangi, M. M. M. Wanyoike
IGC Proceedings (1977-2023)
In this study, the identity of rumen bacterial community and their taxonomic classification in Zebu heifers (n=24) fed 4 different diets (range grasses, Bracharia MulatoII, Azolla and Cassava leaf meal) was surveyed using metagenomics sequencing of the 16SrRNA gene. Rumen liquor samples were collected from the heifers from which a total of 192 DNA samples were amplified and the resulting 16S rRNA sequences compared to the existing sequences at the National Centre for Biotechnology Information (NCBI) BLAST database through the MetagenAssist . Bioinformatics analyses indicated that 17 operational taxonomic units (OTUs) were present at the phylum level. Of these, 43.3% …
Current Status And Future Strategy In Megathyrsus Maximus Breeding Program At The Alliance Bioversity - Ciat, L. M. Hernandez, V. Castiblanco
Current Status And Future Strategy In Megathyrsus Maximus Breeding Program At The Alliance Bioversity - Ciat, L. M. Hernandez, V. Castiblanco
IGC Proceedings (1977-2023)
Megathyrsus maximus (Jacq.) B.K. Simon & S.W.L. Jacobs is one of the most important grass species cultivated for cattle production in cut and carry systems. There is a need to search for superior hybrids with high potential for mitigation and adaptation to climate change. A big proportion of the M. maximus germplasm, preserved in the CIAT GeneBank has been agronomically characterized and genotypes with desirable traits such as high drought tolerance, high BNI potential (Biological nitrification inhibition), high nutritional quality (biomass production, dry matter, crude protein, acid detergent fiber, neutral detergent fiber and dry matter digestibility) and high seed production …
Cross-Protection Against Als-Inhibiting Herbicides In Non-Transgenic Switchgrass Selected For Imazapic Resistance, C. M. Adams, J. I. Morrison, B. S. Baldwin
Cross-Protection Against Als-Inhibiting Herbicides In Non-Transgenic Switchgrass Selected For Imazapic Resistance, C. M. Adams, J. I. Morrison, B. S. Baldwin
IGC Proceedings (1977-2023)
Switchgrass (Panicum virgatum L.) is a North American native warm-season perennial grass that is a cornerstone species in conservation systems and can also be utilized as a high-quality forage. ‘Tusca’ is a cultivar of lowland switchgrass selected from ‘Alamo’ (USDA NRCS, Knox City, TX) for resistance to the herbicide imazapic. This study was conducted to determine if selection in Tusca conferred cross-protection to other ALS-inhibiting herbicides. Five ALS-inhibiting herbicides, including imazapic (IPIC), imazamox (IMOX), imazapyr (IPYR), imazethapyr (ITHR), and metsulfuron methyl (MSUL), were tested on Tusca, Alamo, and wildtype johnsongrass (Sorghum halepense L. (Pers.)) at five rates (25, …
Designing A Clinical Study With Dietary Supplements: It's All In The Details, Z. Elizabeth Floyd, David M. Ribnicky, Ilya Raskin, Daniel S. Hsia
Designing A Clinical Study With Dietary Supplements: It's All In The Details, Z. Elizabeth Floyd, David M. Ribnicky, Ilya Raskin, Daniel S. Hsia
Faculty and Student Publications
A successful randomized clinical trial of the effect of dietary supplements on a chosen endpoint begins with developing supporting data in preclinical studies while paying attention to easily overlooked details when planning the related clinical trial. In this perspective, we draw on our experience studying the effect of an ethanolic extract from Artemisia dracunculus L. (termed PMI-5011) on glucose homeostasis as a potential therapeutic option in providing resilience to metabolic syndrome (MetS). Decisions on experimental design related to issues ranging from choice of mouse model to dosing levels and route of administration in the preclinical studies will be discussed in …
Improving Heifer Development Programs Using Precision Technology And Ddgs, Anna Dagel, Hector Menendez Iii, Jameson R. Brennan
Improving Heifer Development Programs Using Precision Technology And Ddgs, Anna Dagel, Hector Menendez Iii, Jameson R. Brennan
SDSU Beef Day 2022 Summary Publication
Study Description:
Heifers were stratified into two groups based on initial body weight and each group was randomly assigned to one of two treatments: a control group (n=30) and a precision group (n=30). Treatment groups are separated into different pastures to graze dormant native range from November to April. Groups are rotated monthly to reduce individual pasture influence. Heifers in the control group are supplemented as a group and bunk fed 5lb/head/day with dried distiller grain pellets (DDGS). Heifers within the precision group will be supplemented individually using the SmartFeed system (C-Lock Inc. Rapid City, SD) and offered 5lb/head/day DDGS …
Mortality, In-Hospital Morbidity, Care Practices, And 2-Year Outcomes For Extremely Preterm Infants In The Us, 2013-2018, Edward F. Bell, Susan R. Hintz, Nellie I. Hansen, Carla M. Bann, Myra H. Wyckoff, Sara B. Demauro, Michele C. Walsh, Betty R. Vohr, Barbara J. Stoll, Waldemar A. Carlo, Krisa P. Van Meurs, Matthew A. Rysavy, Ravi M. Patel, Stephanie L. Merhar, Pablo J. Sánchez, Abbot R. Laptook, Anna Maria Hibbs, C Michael Cotten, Carl T. D'Angio, Sarah Winter, Janell Fuller, Abhik Das, Eunice Kennedy Shriver National Institute Of Child Health And Human Development Neonatal Research Network
Mortality, In-Hospital Morbidity, Care Practices, And 2-Year Outcomes For Extremely Preterm Infants In The Us, 2013-2018, Edward F. Bell, Susan R. Hintz, Nellie I. Hansen, Carla M. Bann, Myra H. Wyckoff, Sara B. Demauro, Michele C. Walsh, Betty R. Vohr, Barbara J. Stoll, Waldemar A. Carlo, Krisa P. Van Meurs, Matthew A. Rysavy, Ravi M. Patel, Stephanie L. Merhar, Pablo J. Sánchez, Abbot R. Laptook, Anna Maria Hibbs, C Michael Cotten, Carl T. D'Angio, Sarah Winter, Janell Fuller, Abhik Das, Eunice Kennedy Shriver National Institute Of Child Health And Human Development Neonatal Research Network
Pediatrics Research and Scholarship
IMPORTANCE: Despite improvement during recent decades, extremely preterm infants continue to contribute disproportionately to neonatal mortality and childhood morbidity.
OBJECTIVE: To review survival, in-hospital morbidities, care practices, and neurodevelopmental and functional outcomes at 22-26 months' corrected age for extremely preterm infants.
DESIGN, SETTING, AND PARTICIPANTS: Prospective registry for extremely preterm infants born at 19 US academic centers that are part of the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. The study included 10 877 infants born at 22-28 weeks' gestational age between January 1, 2013, and December 31, 2018, including 2566 infants born …
2022-January-18-Isspf Partnership, University Marketing And Communication, East Tennessee State University
2022-January-18-Isspf Partnership, University Marketing And Communication, East Tennessee State University
ETSU News
JOHNSON CITY, Tenn. (Jan. 18, 2022) – A collaboration between the Center of Excellence for Sports Science and Coach Education (CESSCE) at East Tennessee State University and the globally acclaimed International Soccer Science and Performance Federation (ISSPF) has resulted in multiple new shared learning opportunities for students at ETSU.
The news comes as a part of an official announcement on behalf of the ISSPF.
“We are delighted to partner with ETSU. We are extremely excited to play a fundamental part in the development of online sport and soccer science and coaching related individuals in a region known for its love …
Reactive Oxygen Species (Ros) And Antioxidants As Immunomodulators In Exercise: Implications For Heme Oxygenase And Bilirubin, David Travis Thomas, Nicholas R. Delcimmuto, Kyle D. Flack, David E. Stec, Terry D. Hinds Jr.
Reactive Oxygen Species (Ros) And Antioxidants As Immunomodulators In Exercise: Implications For Heme Oxygenase And Bilirubin, David Travis Thomas, Nicholas R. Delcimmuto, Kyle D. Flack, David E. Stec, Terry D. Hinds Jr.
Athletic Training and Clinical Nutrition Faculty Publications
Exercise is commonly prescribed as a lifestyle treatment for chronic metabolic diseases as it functions as an insulin sensitizer, cardio-protectant, and essential lifestyle tool for effective weight maintenance. Exercise boosts the production of reactive oxygen species (ROS) and subsequent transient oxidative damage, which also upregulates counterbalancing endogenous antioxidants to protect from ROS-induced damage and inflammation. Exercise elevates heme oxygenase-1 (HO-1) and biliverdin reductase A (BVRA) expression as built-in protective mechanisms, which produce the most potent antioxidant, bilirubin. Together, these mitigate inflammation and adiposity. Moderately raising plasma bilirubin protects in two ways: (1) via its antioxidant capacity to reduce ROS and …
Amplification Of Emerging Viruses In A Bat Colony, Jan Felix Drexler, Victor Max Corman, Tom Wegner
Amplification Of Emerging Viruses In A Bat Colony, Jan Felix Drexler, Victor Max Corman, Tom Wegner
KIP Articles
Bats host noteworthy viral pathogens, including coronaviruses, astroviruses, and adenoviruses. Knowledge on the ecology of reservoir-borne viruses is critical for preventive approaches against zoonotic epidemics. We studied a maternity colony of Myotis myotis bats in the attic of a private house in a suburban neighborhood in Rhineland-Palatinate, Germany, during 2008, 2009, and 2010. One coronavirus, 6 astroviruses, and 1 novel adenovirus were identified and monitored quantitatively. Strong and specific amplification of RNA viruses, but not of DNA viruses, occurred during colony formation and after parturition. The breeding success of the colony was significantly better in 2010 than in 2008, in …
Exploration Of Factors That Promote Continued Volunteer Engagement Of American Red Cross Disaster Health Services Nurses, Kathleen V. Eid-Heberle
Exploration Of Factors That Promote Continued Volunteer Engagement Of American Red Cross Disaster Health Services Nurses, Kathleen V. Eid-Heberle
Dissertations
The purpose of the research study was to explore factors that promote continued volunteer engagement of American Red Cross Disaster Health Services (DHS) nurses.
Designing A Clinical Study With Dietary Supplements: It's All In The Details, Z. Elizabeth Floyd, David M. Ribnicky, Ilya Raskin, Daniel S. Hsia, Jennifer C. Rood, Bill J. Gurley
Designing A Clinical Study With Dietary Supplements: It's All In The Details, Z. Elizabeth Floyd, David M. Ribnicky, Ilya Raskin, Daniel S. Hsia, Jennifer C. Rood, Bill J. Gurley
Division of Basic Science Faculty Publications
A successful randomized clinical trial of the effect of dietary supplements on a chosen endpoint begins with developing supporting data in preclinical studies while paying attention to easily overlooked details when planning the related clinical trial. In this perspective, we draw on our experience studying the effect of an ethanolic extract from Artemisia dracunculus L. (termed PMI-5011) on glucose homeostasis as a potential therapeutic option in providing resilience to metabolic syndrome (MetS). Decisions on experimental design related to issues ranging from choice of mouse model to dosing levels and route of administration in the preclinical studies will be discussed in …
Effects Of Foliar Application Of Zno Nanoparticles On Lentil Production, Stress Level And Nutritional Seed Quality Under Field Conditions, Marek Kolenčík, Dávid Ernst, Matej Komár, Martin Urík, Martin Šebesta, Ľuba Ďurišová, Marek Bujdoš, Ivan Černý, Juraj Chlpík, Martin Juriga, Ramakanth Illa, Yu Qian, Huan Feng, Gabriela Kratošová, Karla Čech Barabaszová, Ladislav Ducsay, Elena Aydın
Effects Of Foliar Application Of Zno Nanoparticles On Lentil Production, Stress Level And Nutritional Seed Quality Under Field Conditions, Marek Kolenčík, Dávid Ernst, Matej Komár, Martin Urík, Martin Šebesta, Ľuba Ďurišová, Marek Bujdoš, Ivan Černý, Juraj Chlpík, Martin Juriga, Ramakanth Illa, Yu Qian, Huan Feng, Gabriela Kratošová, Karla Čech Barabaszová, Ladislav Ducsay, Elena Aydın
Department of Earth and Environmental Studies Faculty Scholarship and Creative Works
Nanotechnology offers new opportunities for the development of novel materials and strategies that improve technology and industry. This applies especially to agriculture, and our previous field studies have indicated that zinc oxide nanoparticles provide promising nano-fertilizer dispersion in sustainable agriculture. However, little is known about the precise ZnO-NP effects on legumes. Herein, 1 mg·L−1 ZnO-NP spray was dispersed on lentil plants to establish the direct NP effects on lentil production, seed nutritional quality, and stress response under field conditions. Although ZnO-NP exposure positively affected yield, thousand-seed weight and the number of pods per plant, there was no statistically significant …
Which Exercise Interventions Can Most Effectively Improve Reactive Balance In Older Adults? A Systematic Review And Network Meta-Analysis, Youngwook Kim, Michael N. Vakula, David A. E. Bolton, Christopher J. Dakin, Brennan J. Thompson, Timothy A. Slocum, Masaru Teramoto, Eadric Bressel
Which Exercise Interventions Can Most Effectively Improve Reactive Balance In Older Adults? A Systematic Review And Network Meta-Analysis, Youngwook Kim, Michael N. Vakula, David A. E. Bolton, Christopher J. Dakin, Brennan J. Thompson, Timothy A. Slocum, Masaru Teramoto, Eadric Bressel
Kinesiology and Health Science Faculty Publications
Background: Reactive balance is the last line of defense to prevent a fall when the body loses stability, and beneficial effects of various exercise-based interventions on reactive balance in older adults have been reported. However, their pooled evidence on the relative effects has yet to be described. Objective: To review and evaluate the comparative effectiveness of various exercise-based interventions on reactive balance in older adults. Methods: Nine electronic databases and reference lists were searched from inception to August 2021. Eligibility criteria according to PICOS criteria were as follows: (1) population: older adults with the mean age of 65 years or …
Risk Of Food Insecurity In Undocumented Migrant Households In Birmingham, Uk, A Jolly, J Thompson
Risk Of Food Insecurity In Undocumented Migrant Households In Birmingham, Uk, A Jolly, J Thompson
School of Health Professions
Background This study aimed to understand the extent of household food insecurity amongst undocumented migrant families in Birmingham,UK. Methods Cross-sectional survey of households (n = 74) with dependent children using the USDA 18-item household food security (HFS) module. All households had an irregular immigration status and were accessing an immigration advice drop-in service (n = 98 adults; n = 138 children) in Birmingham. Results About 95.9% of households were food insecure, and 94.6% of children lived in households with low or very low food security. Food insecurity varied within households. Around 91.8% of adults were food insecure, compared to 75.6% …
Characterizing Human Gut Bacterial Tir Domains In Vitro, In Gnotobiotic Mice And Malnourished Children, James Stephen Weagley
Characterizing Human Gut Bacterial Tir Domains In Vitro, In Gnotobiotic Mice And Malnourished Children, James Stephen Weagley
Arts & Sciences Graduate Student Theses and Dissertations
Worldwide, malnutrition (undernutrition) is the leading cause of death in children under 5. Studies of healthy members of birth cohorts from low- and middle-income countries have identified a program of gut microbial community development that is disrupted in children with severe acute malnutrition (SAM) and moderate acute malnutrition (MAM). This perturbed gut microbiome development has been linked to the pathogenesis of malnutrition. Repair of this gut microbial dysbiosis in children with MAM with microbiota-directed complementary foods (MDCFs) designed to increase the fitness and expressed beneficial functions of underrepresented bacterial community members restores healthy growth, including improvements in mediators of metabolic …
Rspo2 And Rankl Signal Through Lgr4 To Regulate Osteoclastic Premetastatic Niche Formation And Bone Metastasis, Zhiying Yue, Xin Niu, Zengjin Yuan, Qin Qin, Wenhao Jiang, Liang He, Jingduo Gao, Yi Ding, Yanxi Liu, Ziwei Xu, Zhenxi Li, Zhengfeng Yang, Rong Li, Xiwen Xue, Yankun Gao, Fei Yue, Xiang H-F Zhang, Guohong Hu, Yi Wang, Yi Li, Geng Chen, Stefan Siwko, Alison Gartland, Ning Wang, Jianru Xiao, Mingyao Liu, Jian Luo
Rspo2 And Rankl Signal Through Lgr4 To Regulate Osteoclastic Premetastatic Niche Formation And Bone Metastasis, Zhiying Yue, Xin Niu, Zengjin Yuan, Qin Qin, Wenhao Jiang, Liang He, Jingduo Gao, Yi Ding, Yanxi Liu, Ziwei Xu, Zhenxi Li, Zhengfeng Yang, Rong Li, Xiwen Xue, Yankun Gao, Fei Yue, Xiang H-F Zhang, Guohong Hu, Yi Wang, Yi Li, Geng Chen, Stefan Siwko, Alison Gartland, Ning Wang, Jianru Xiao, Mingyao Liu, Jian Luo
Faculty, Staff and Students Publications
Therapeutics targeting osteoclasts are commonly used treatments for bone metastasis; however, whether and how osteoclasts regulate premetastatic niche and bone tropism are largely unknown. In this study, we report that osteoclast precursors (OPs) can function as a premetastatic niche component that facilitates breast cancer (BCa) bone metastasis at early stages. At the molecular level, unbiased GPCR ligand/agonist screening in BCa cells suggested that R-spondin 2 (RSPO2) and RANKL, through interaction with their receptor LGR4, promoted osteoclastic premetastatic niche formation and enhanced BCa bone metastasis. This was achieved by RSPO2/RANKL-LGR4 signal modulating the WNT inhibitor DKK1 through Gαq and β-catenin signaling. …
Changes In Defoliation Patterns Of Plant Functional Groups Under Variable Herbage Allowance In Campos Grasslands, N. Caram, F. Casalás, Pablo Soca, M. Wallau, M. Cadenazzi, P. Boggiano
Changes In Defoliation Patterns Of Plant Functional Groups Under Variable Herbage Allowance In Campos Grasslands, N. Caram, F. Casalás, Pablo Soca, M. Wallau, M. Cadenazzi, P. Boggiano
IGC Proceedings (1977-2023)
Several studies have evaluated separately forage production, botanical composition, leaf traits and animal performance. However, few of them have focused on defoliation patterns at the level of functional groups (FGs) under different and variable herbage allowance (HA), especially in natural, diverse grasslands. The objective was to evaluate the relationship between HA and leaf traits on defoliation patterns of mature beef cows in the autumn, winter and spring. We evaluated the grazing probability (GP), intensity of defoliation (ID), and leaf traits on 14 species that represent more than 80% of total dry matter of the pasture. The experiment at which we …
Detoxification Of Copper And Chromium Via Dark Hydrogen Fermentation Of Potato Waste By Clostridium Butyricum Strain 92, Vira Hovorukha, Olesia Havryliuk, Galina Gladka, Antonina Kalinichenko, Monika Sporek, Jan Stebila, Dmitri Mavrodi, Ruslan Mariychuk, Oleksandr Tashyrev
Detoxification Of Copper And Chromium Via Dark Hydrogen Fermentation Of Potato Waste By Clostridium Butyricum Strain 92, Vira Hovorukha, Olesia Havryliuk, Galina Gladka, Antonina Kalinichenko, Monika Sporek, Jan Stebila, Dmitri Mavrodi, Ruslan Mariychuk, Oleksandr Tashyrev
Faculty Publications
The accumulation of various types of waste containing both organic and inorganic metal-containing compounds is extremely hazardous for living organisms. The possibility of polymer degradation, biohydrogen synthesis, and metal detoxification via the dark fermentation of model potato waste was investigated. For this purpose, the strict anaerobic strain was isolated and identified as Clostridium butyricum. The high efficiency of dark hydrogen fermentation of potatoes with yield of hydrogen in 85.8 ± 15.3 L kg−1 VSpotato was observed. The copperand chromium salts solutions were added to the culture fluid to obtain the concentrations of 50, 100, and 200 mg …
Shelly Mohr - Covid 19 Oral History Project, Shelly Mohr, Institute Of Child Nutrition. Child Nutrition Archives.
Shelly Mohr - Covid 19 Oral History Project, Shelly Mohr, Institute Of Child Nutrition. Child Nutrition Archives.
Oral History Project (all interviews)
During 2022 the Child Nutrition Archives conducted multiple interviews investigating how child nutrition professionals dealt with the Covid 19 pandemic and its effects on the operations of school feeding programs. This interview examines the experiences of Shelly Mohr. Mohr is in her 23rd year as a Food Service Director in a K-12 School District.
Impact Pathways From Climate Services To Sdg2 (“Zero Hunger”): A Synthesis Of Evidence, James Hansen, Geneva List, Shauna Downs, Edward Carr, Rahel Diro, Walter Baethgen, Andrew Kruczkiewicz, Melody Braun, John Furlow, Kayla Walsh, Nitin Magima
Impact Pathways From Climate Services To Sdg2 (“Zero Hunger”): A Synthesis Of Evidence, James Hansen, Geneva List, Shauna Downs, Edward Carr, Rahel Diro, Walter Baethgen, Andrew Kruczkiewicz, Melody Braun, John Furlow, Kayla Walsh, Nitin Magima
Sustainability and Social Justice
Climate services can help address a range of climate-sensitive development challenges, including agricultural production and food security. However, generating empirical evidence of impact is challenging. In this paper, we synthesize published evidence of pathways by which climate services contribute to improved food security. A summary of key mechanisms by which climate risk drives food insecurity provides a context for understanding potential climate risk management interventions. Our review of available evaluation literature finds moderately strong evidence that climate services contribute to improvements in food security or its precursors through farmers’ risk management decisions and index-based agricultural insurance; and a weaker body …
Synthesis And Biosynthesis Of 3-Hydroxy-Β-Lactam Antibiotics, Wei Wei
Synthesis And Biosynthesis Of 3-Hydroxy-Β-Lactam Antibiotics, Wei Wei
Arts & Sciences Graduate Student Theses and Dissertations
Novel treatments for tuberculosis (TB) are urgently needed to conquer this global health crisis. Unlike canonical β-lactam antibiotics that target transpeptidases by hydrolyzing the lactam ring, tabtoxinine-β-lactam (TβL) functions as a potent glutamine synthetase (GS) inhibitor by forming a transition state mimic. TβL has the potential to be used as an anti-TB agent by targeting the nitrogen metabolic pathway of pathogenic mycobacteria. This work reported an innovative, convergent, and flexible cross-metathesis method to obtain the fully protected TβL scaffold. The trans-olefin intermediate provides possibilities for synthesizing various derivatives through alkene functionalization reactions. We also developed and optimized a solid phase …
Nature Of Health Insurance Demand In India, Brijesh C. Purohit Ph.D
Nature Of Health Insurance Demand In India, Brijesh C. Purohit Ph.D
Himalayan Research Papers Archive
In this study an attempt is made to explore elasticity of health insurance demand in India. It is important to note that both the Central and state governments have been trying to help people through their budgetary policies. Keeping in view their efforts and rural urban disparities in the country, we have tried to make an attempt to evaluate whether the people have been provided appropriate information about these governmental policies and how other socio economic factors are influencing the individual household choices to adopt a particular type of health insurance scheme.
This is based on latest National Family Health …
Differences In Health-Related Outcomes And Health Care Resource Utilization In Breast Cancer Survivors With And Without Type 2 Diabetes, Susan Storey, Zuoyi Zhang, Xiao Luo, Megan Metzger, Amrutha Ravali Jakka, Kun Huang, Diane Von Ah
Differences In Health-Related Outcomes And Health Care Resource Utilization In Breast Cancer Survivors With And Without Type 2 Diabetes, Susan Storey, Zuoyi Zhang, Xiao Luo, Megan Metzger, Amrutha Ravali Jakka, Kun Huang, Diane Von Ah
Journal of Patient-Centered Research and Reviews
Purpose: Up to 74% of breast cancer survivors (BCS) have at least one preexisting comorbid condition, with diabetes (type 2) common. The purpose of this study was to examine differences in health-related outcomes (anemia, neutropenia, and infection) and utilization of health care resources (inpatient, outpatient, and emergency visits) in BCS with and without diabetes.
Methods: In this retrospective cohort study, data were leveraged from the electronic health records of a large health network linked to the Indiana State Cancer Registry. BCS diagnosed between January 2007 and December 2017 and who had received chemotherapy were included. Multivariable logistic regression and generalized …
Prevalence Of Endocrine Disorders Among 6078 Individuals With Down Syndrome In The United States, Anne Rivelli, Veronica Fitzpatrick, Danielle Wales, Laura Chicoine, Gengjie Jia, Andrey Rzhetsky, Brian Chicoine
Prevalence Of Endocrine Disorders Among 6078 Individuals With Down Syndrome In The United States, Anne Rivelli, Veronica Fitzpatrick, Danielle Wales, Laura Chicoine, Gengjie Jia, Andrey Rzhetsky, Brian Chicoine
Journal of Patient-Centered Research and Reviews
Findings from a recent study describing prevalence of common disease conditions in the largest documented cohort of individuals with Down syndrome (DS) in the United States strongly suggested significant disparity in endocrine disorders among these individuals when compared with age- and sex-matched individuals without DS. This retrospective, descriptive study is a follow-up report documenting prevalence of 21 endocrine disorder conditions, across 28 years of data, from 6078 individuals with DS and 30,326 age- and sex-matched controls, abstracted from electronic medical records within a large integrated health system. Overall, individuals with DS experienced higher prevalence of adrenal insufficiency and Addison’s disease; …
Directly Observed Weekly Fluoxetine For Major Depressive Disorder Among Hemodialysis Patients: A Single-Arm Feasibility Trial, Kelley M. Kauffman, Jacqueline Dolata, Maria Figueroa, Douglas Gunzler, Anne Huml, Julie Pencak, Martha Sajatovic, Ashwini R. Sehgal
Directly Observed Weekly Fluoxetine For Major Depressive Disorder Among Hemodialysis Patients: A Single-Arm Feasibility Trial, Kelley M. Kauffman, Jacqueline Dolata, Maria Figueroa, Douglas Gunzler, Anne Huml, Julie Pencak, Martha Sajatovic, Ashwini R. Sehgal
Faculty Scholarship
Rationale & Objective: Major depressive disorder (MDD) is common among hemodialysis patients, but treatment can add to their pill burden and may be limited by nonadherence. We sought to investigate the value of directly observed, once-weekly fluoxetine dosing in MDD. Study Design: Feasibility trial of adult hemodialysis patients with untreated MDD. The diagnosis of MDD was determined using the Mini International Neuropsychiatric Interview. Setting & Participants: 16 patients at 15 hemodialysis facilities in Northeast Ohio. Intervention: Patients were initially prescribed 20 mg of fluoxetine once daily for 2 weeks to assess their tolerance. The patients took this daily fluoxetine unobserved …
Oil Palm Crop: State And Gaps Of Research And Technological Development At Global Scale, Latin America And Mexico, Luz Del Carmen Lagunes-Espinoza, César Jesús Vazquez-Navarrete, Joaquín Alberto Rincón-Ramirez, Kathleen Halvorsen
Oil Palm Crop: State And Gaps Of Research And Technological Development At Global Scale, Latin America And Mexico, Luz Del Carmen Lagunes-Espinoza, César Jesús Vazquez-Navarrete, Joaquín Alberto Rincón-Ramirez, Kathleen Halvorsen
Michigan Tech Publications, Part 1
Oil palm plantations face important challenges in terms of balancing agricultural productivity and environmental sustainability. This research synthesis aims to answer key questions regarding the state and knowledge gaps of oil palm (OP) research and technological development (R&D) at a global scale, in Latin America and in Mexico, using all Web of Science® databases and agriculture categories and time spans between 1960 and 2018. Three thousand nine hundred and forty-eight publications were analysed. The research themes started with the generation of agronomic knowledge in 1960. Since 1963, studies in Latin America have focused on yield improvement; since 2010, topics related …
Post-Hpv-Vaccination Mast Cell Activation Syndrome: Possible Vaccine-Triggered Escalation Of Undiagnosed Pre-Existing Mast Cell Disease?, Lawrence B Afrin, Tania T Dempsey, Leonard B Weinstock
Post-Hpv-Vaccination Mast Cell Activation Syndrome: Possible Vaccine-Triggered Escalation Of Undiagnosed Pre-Existing Mast Cell Disease?, Lawrence B Afrin, Tania T Dempsey, Leonard B Weinstock
Open Access Publications
For nearly a decade, case reports and series have emerged regarding dysautonomias-particularly postural orthostatic tachycardia syndrome (POTS)-presenting soon after vaccination against human papilloma virus (HPV). We too have observed a number of such cases (all following vaccination with the Gardasil product), and have found several to have detectable mast cell activation syndrome (MCAS) as well as histories suggesting that MCAS was likely present long before vaccination. We detail 11 such cases here, posing a hypothesis that HPV vaccination (at least with the Gardasil product) may have triggered or exacerbated MCAS in teenagers previously not recognized to have it. Only recently …