Digital Commons Network^™

The Long-Term Health And Developmental Impacts Of Children Born At Low Birth Weight, Kathryn Grace Kelly

Honors Theses

The state of Mississippi currently has the highest incidence of low birth weight (LBW) births in the United States. LBW is a negative birth outcome which can lead to suboptimal pediatric health and development. The primary goals of this thesis are to identify the long-term outcomes associated with LBW and to present potential interventions to address LBW. A combination of literature review and quantitative data analysis were used to inform the objective of this thesis. A variety of physical health, behavioral health, and other long-term issues were found associated with LBW. The consequences of LBW place LBW children at a …

College Students Fail To Identify Nutrition Misinformation On Social Media, Helen Mary Katool

Honors Theses

Social media has become a part of everyday life in our society and has the capability to reach billions, across age groups. Research has shown that there is a direct link between the widespread access to social media and the amount of misinformation that is circulating. In fact, unqualified and uneducated individuals share believable but inaccurate nutrition posts. Therefore, the purpose of this study is to determine if college students can distinguish the difference between nutrition misinformation or factual nutrition information when presented on social media. Male and female college students (>18 years old) from two classes (nutrition and …

Optimizing Intrapartum Outcomes For Midwifery Patients With Obesity, Anna Shields

Doctor of Nursing Practice Scholarly Projects

Existing literature has established that laboring people with obesity have poorer intrapartum outcomes compared to their lower weight counterparts, including elevated c-section rates which increase with increasing BMI. People with obesity are at increased risk for complications related to surgical birth so optimizing chances for vaginal delivery is of utmost importance yet professional guidelines about labor management are lacking. Research has established that people with obesity have longer times in labor especially early labor, need more labor stimulating medications and have physiologic changes that alter the labor process compared to lower weight people. Literature on the impact of midwifery care …

What Is The Satisfaction Of Youth Participating In A Pilot Reading And Food-Based Stem Education Program In Rural Appalachian Mississippi?, Meagan Smith

Honors Theses

Science, technology, engineering, and mathematics (STEM) education is a vital subsection of primary education which focuses on imparting knowledge to foster STEM literacy and ultimately bolster the workforce of STEM related fields (Holmlund, 2018). Due to both geographic and socioeconomic challenges, STEM education in rural areas suffers from a lack of engaging learning opportunities and contributes to a shortage of STEM professionals originating from rural areas (Munn, 2019)(Murphy, 2020). Rural areas such as Calhoun County, MS, where the pilot program associated with this thesis was conducted, do not have the means to support interactive learning institutions such as aquariums and …

Evaluating The Barriers Of Entry That Small Commercial Farmers Face And The Implications Of Such Barriers On Rural Communities, Lauren C. Chandler

Honors Theses

The research proposed in this thesis will identify the barriers of entry that

small farmers face when entering the Agricultural Industry. The proposed research will also seek to discover how having these barriers in place affects rural communities. This thesis conducts a literature review of the topic, sets the context for the research to be done, and proposes a research project to further investigate the topic. The proposed research will be done through administering a survey to stakeholders, and then interviewing a small sample of those surveyed to get a comprehensive look at the effects of agribusiness on rural communities. …

Implementation Of Enhanced Recovery After Surgery (Eras) Guidelines: A Comprehensive Interdisciplinary Approach, Christopher N. Stoner Bsn, Rn, Alex R. Priest Bsn, Rn, Dwayne Accardo Dnp, Crna, Aprn

Doctor of Nursing Practice Projects

Purpose/Background Enhance Recovery After Surgery (ERAS) protocols are multimodal transdisciplinary care guidelines that can improve clinical outcomes and cost savings. Although surgical practices currently vary significantly among healthcare institutions, perioperative outcomes and safety appear to improve with ERAS pathways. This scoping review evaluates patient outcomes and satisfaction in adult patients during their first week postoperatively while utilizing ERAS pathways.

Methods This scoping review includes a variety of peer-reviewed and published academic journals within the last five years to guarantee the information surveyed is current. Even though this scoping review focuses on the interdisciplinary method to executing ERAS pathways, studies demonstrating …

Blue Zones: Unlocking Key Themes In The Centenarian's Life, Grace Beer, Grace O. Beer

Honors College Theses

Longevity has been sought after in certain areas of the world, and there are specific regions where this has been achieved. There is an American average life expectancy of 72 years old, but individuals in “Blue Zones” here in America and other areas of the world are expected to and have proven to live well beyond 100. The areas of Okinawa, Sardinia, Nicoya, Ikaria, and Loma Linda are classified as Blue Zones, and there could be more of an understanding of how these people live the way they do to have such healthy physical outcomes. To deeply understand the strategy …

The Appropriate Initiation Of Parenteral Nutrition Per Aspen Criteria In A Community Hospital, Adrian Gavre, Hyeseung Kang, Dewayne Cross

Research Day

Introduction

The American Society for Parenteral and Enteral Nutrition (ASPEN) has published guidelines for the proper initiation of parenteral nutrition (PN) in order to safelyadminister PN.

Objective

The objective of this study is to determine the amount of PN orders that were appropriately initiated according to ASPEN guidelines within the WellStar North Fulton campus.

Methods

This study is a single-center, retrospective chart review over 30 months. The data was collected from Wellstar North Fulton Hospital patients from January 1st, 2019, to July 19th, 2021. The sample size is 115 patients. Appropriate initiation of PN was determined by analyzing how PN …

Increased Prevalence Of Parenteral Nutrition-Associated Liver Disease In Neonates With Congenital Heart Disease, Yasasvhinie Santharam

Research Days

Background: A life-sustaining therapy, use of total parenteral nutrition (TPN) allows for meeting nutritional needs of low birth weight, premature, or otherwise complex infants with conditions that prevent feeding through the GI tract. However, 40-60% of infants on long-term TPN have been shown to develop parenteral nutrition-associated liver disease (PNALD)1 , a serious condition characterized by cholestatic jaundice, steatosis, and hepatic fibrosis. Given these risks, providers must account for risk of hepatic injury when prescribing TPN, including attributes of gestational age, infection, surgical and diagnosis history2-6 . Yet with a multifactorial pathogenesis, significant heterogeneity in PNALD incidence still occurs. Looking …

Organized Savagery: Legitimization Of British Occupation In The Post-Ottoman State, Jamie M. Emerson

The Purdue Historian

The Great War of 1914-1918 saw the internment of hundreds of thousands of prisoners of war, captured and maintained by the hand of their enemy. Allegations and accounts of ill-treatment under the enemy’s care abounded during and after the war. Leading up to the Peace Conference of 1919, negotiators chose to account for the suffering of these prisoners in their demands for indemnities and reparations. This paper assesses how the British Parliament and press used stories about the suffering of British and Indian prisoners of war in Ottoman internment camps as a means to delegitimize Ottoman rule and legitimize British …

Role Of Fasting In Caloric Restriction Improved Glucose Tolerance, Makayla M. Dillon

ETD Archive

The Caloric Restriction (CR) diet in mammals has been shown to increase longevity and prevent metabolic disorders. Some of the benefits of CR include improved glucose homeostasis, namely improvements in glucose tolerance. Mice on the CR diet have a 30% reduction in food provided, as well as a fasting period between meals as they are only fed once a day. Hence the benefits of CR stem from both fasting and reduced calorie intake. In this study, we investigated if the fasting component of CR is responsible for the benefits of this diet in improving glucose homeostasis. In particular, we used …

Sociology Of The Family Textbook, Amy E. Traver

Open Educational Resources

This OER textbook provides students with a brief introduction to: the perspective, methods, and theories that constitute the sociology of the family; research on patterns and processes of dating/mating, cohabitation/marriage, parenting. divorce/remarriage, and family stressors/strengths in the United States. It was created through the integration of various OER texts, including OpenStax, Sociology Wikibooks, and many more. It is licensed under a Creative Commons Attribution-Noncommercial-Share Alike 4.0 license.

Academic Senate - Agenda, 5/3/2022, Academic Senate

Academic Senate Agendas

No abstract provided.

Infrastructure And Policies Supporting Physical Activity Habits: A Comparison Between The United States And Europe, Anisha Laddha

Honors College Theses

Most adults in the United States are not getting enough physical activity, and this is causing high rates of adverse health conditions such as diabetes and cardiovascular disease in the population. The rising costs of cardiovascular disease are a national problem that must be tackled from multiple perspectives. This literature review explores policies and infrastructure implemented in European countries with better health outcomes and higher physical activity levels in the population compared to the United States. The infrastructure in places such as Germany and Denmark is constructed to encourage physical activity in the form of active transportation such as walking …

Empower You: An Adult Type 2 Diabetes Mellitus Management Program With Utilization Of A Mobile Phone Application, Kelsey Jahn

Evidence-Based Practice Project Reports

In 2018, 34.2 million Americans had diabetes and there continues to be 1.5 million Americans diagnosed with diabetes every year (ADA, 2018). Due to this increasing prevalence, self-management of type 2 diabetes mellitus (T2DM) is essential to disease management. The PICOT question for this project was: In adults with T2DM with a hemoglobin A1C (HbA1C) greater than 8% in a diabetes specialty clinic (P), what is the effect of a multimodal smartphone application (I) compared to prior nonuse of the application (C) on average blood glucose readings (O) over an 8-week period (T)? The project was completed in a large, …

Screening And Follow Up For Postpartum Depression: How To Improve Practice, Mallory Matusik

Evidence-Based Practice Project Reports

Postpartum depression (PPD) is one of the most common mental health conditions, affecting one in seven women during their reproductive years (American College of Obstetricians and Gynecologists [ACOG], 2018). The purpose of this evidence-based practice (EBP) project was to improve screening and management of PPD using the Edinburgh Postnatal Depression Scale (EPDS) screening tool and a protocol for appropriate treatment and follow up care for PPD. A protocol was created by the project leader with information on screening and diagnosis, follow up, and treatment for PPD. The protocol also included information on how to assess for suicidal and/or homicidal ideation …

Back To The Basics With Smart Goals: A Multimodal Intervention For Adults Who Have Type 2 Diabetes, Alyssa L. Snyder

Evidence-Based Practice Project Reports

Diabetes, the seventh leading cause of death in the United States (Centers for Disease Control and Prevention [CDC], 2020a) and the ninth leading cause of death worldwide (World Health Organization [WHO], 2020), has increased by 70% over the last two decades (WHO, 2020). Type 2 diabetes (T2D), the most prevalent type accounting for 90% to 95% of diagnosed cases (CDC, 2020a), affects individuals of all ages and often results in major health problems including stroke, heart attack, and kidney disease. The purpose of this patient-centered, evidence-based practice (EBP) project was to evaluate the effectiveness of a multimodal intervention on hemoglobin …

Bacille Calmette-Guérin Vaccine Reprograms Human Neonatal Lipid Metabolism In Vivo And In Vitro, Joann Diray-Arce, Asimenia Angelidou, Kristoffer Jarlov Jensen, Maria Giulia Conti, Rachel S Kelly, Matthew Pettengill, Mark Liu, Simon D Van Haren, Scott D Mcculloch, Greg Michelloti, Olubukola Idoko, Tobias R Kollmann, Beate Kampmann, Hanno Steen, Al Ozonoff, Jessica Lasky-Su, Christine S Benn, Ofer Levy

Department of Pathology, Anatomy, and Cell Biology Faculty Papers

Vaccines have generally been developed with limited insight into their molecular impact. While systems vaccinology enables characterization of mechanisms of action, these tools have yet to be applied to infants, who are at high risk of infection and receive the most vaccines. Bacille Calmette-Guérin (BCG) protects infants against disseminated tuberculosis (TB) and TB-unrelated infections via incompletely understood mechanisms. We employ mass-spectrometry-based metabolomics of blood plasma to profile BCG-induced infant responses in Guinea-Bissau in vivo and the US in vitro. BCG-induced lysophosphatidylcholines (LPCs) correlate with both TLR-agonist- and purified protein derivative (PPD, mycobacterial antigen)-induced blood cytokine production in vitro, raising the …

Development Of An Analytical Method For Determination Of Lead And Cadmium In Biological Materials By Gfaas Using Escherichia Coli As Model Substance, Michelle Catherine Gende, Martina Schmeling

Chemistry: Faculty Publications and Other Works

In this work, an analytical method was developed for the determination of lead and cadmium in biological samples using graphite furnace atomic absorption spectrometry. Escherichia coli (E. coli) was chosen as model substance for this purpose as it is readily available in most laboratories and can be quickly and easily prepared with a high turnaround rate. Four different sample preparation methods were initially evaluated with respect to percent recovery, limit of detection, and limit of quantification, and the most promising one was developed further. The final process involving microwave assisted digestion of the sample with nitric acid …

Great Northern Beans (Phaseolus Vulgaris L.) Lower Cholesterol In Hamsters Fed A High-Saturated-Fat Diet, An T. Nguyen, Sami A. Althwab, Haowen Qiu, Richard Zbasnik, Carlos A. Urrea, Timothy P. Carr, Vicki Schlegel

Department of Food Science and Technology: Faculty Publications

Background: Dietary interventions for high cholesterol, a primary risk factor for cardiovascular disease, are generally considered before prescribing drugs.

Objective: This study investigated the effects of whole Great Northern beans (wGNBs) and their hull (hGNB) incorporated into a high-saturated-fat (HSF) diet on cholesterol markers and hepatic/small intestinal genes involved in cholesterol regulation.

Methods: Each of the 4 groups of 11 male golden Syrian hamsters at 9 wk old were fed a normal-fat [NF; 5% (wt:wt) of soybean oil], HSF [5% (wt:wt) of soybean oil + 10% (wt:wt) of coconut oil], HSF+5% (wt:wt) wGNB, or HSF+0.5% (wt:wt) hGNB diet for 4 …

Systems Biology Approach To Functionally Assess The Clostridioides Difficile Pangenome Reveals Genetic Diversity With Discriminatory Power, Charles J Norsigian, Heather A Danhof, Colleen K Brand, Firas S Midani, Jared T Broddrick, Tor C Savidge, Robert A Britton, Bernhard O Palsson, Jennifer K Spinler, Jonathan M Monk

Faculty, Staff and Students Publications

Combatting Clostridioides difficile infections, a dominant cause of hospital-associated infections with incidence and resulting deaths increasing worldwide, is complicated by the frequent emergence of new virulent strains. Here, we employ whole-genome sequencing, high-throughput phenotypic screenings, and genome-scale models of metabolism to evaluate the genetic diversity of 451 strains of C. difficile. Constructing the C. difficile pangenome based on this set revealed 9,924 distinct gene clusters, of which 2,899 (29%) are defined as core, 2,968 (30%) are defined as unique, and the remaining 4,057 (41%) are defined as accessory. We develop a strain typing method, sequence typing by accessory genome (STAG), …

Vikela Ekhaya: A Novel, Community-Based, Tuberculosis Contact Management Program In A High Burden Setting, Alexander W Kay, Micaela Sandoval, Godwin Mtetwa, Musa Mkhabela, Banele Ndlovu, Tara Devezin, Welile Sikhondze, Debrah Vambe, Joyce Sibanda, Gloria S Dube, Robert H Stevens, Bhekumusa Lukhele, Anna M Mandalakas

Faculty, Staff and Student Publications

BACKGROUND: The prevention of tuberculosis (TB) in child contacts of TB cases and people living with human immunodeficiency virus (HIV) is a public health priority, but global access to TB preventive therapy (TPT) remains low. In 2019, we implemented Vikela Ekhaya, a novel community-based TB contact management program in Eswatini designed to reduce barriers to accessing TPT.

METHODS: Vikela Ekhaya offered differentiated TB and HIV testing for household contacts of TB cases by using mobile contact management teams to screen contacts, assess their TPT eligibility, and initiate and monitor TPT adherence in participants' homes.

RESULTS: In total, 945 contacts from …

Gastrointestinal Fibromatosis: A Case Of Successful Oral Tyrosine Kinase Inhibitor Delivery To An Infant With Proximal Duodenal Obstruction, Darius Blanding

Research Days

Background: Infantile myofibromatosis (IM) is a rare disorder characterized by the fibrous proliferation of the skin, bone, muscle, and viscera that usually presents at birth, or soon after. Although IM is a benign condition, significantly higher morbidity and mortality have been reported when the viscera is involved. This case report is of a 6-week-old female who presented with poor feeding along with subcutaneous nodules that were diagnosed as IM. Upper and lower endoscopy were performed for worsening feeding intolerance showing marked nodularity throughout the gastrointestinal (GI) tract, including partial obstruction of the proximal duodenum by biopsy-proven myofibromas, confirming visceral IM …

Impacts Of Added Roughage On Growth Performance, Digestibility, Ruminal Fermentation, And Ruminal Ph Of Feedlot Steers Fed Wheat-Based Feedlot Diets Containing 30% Modified Distillers Grains With Solubles, Wayde J. Pickinpaugh, Bryan W. Neville, Rebecca L. Moore, Joel S. Caton

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Two experiments were conducted to evaluate the inclusion rate roughage in wheat-based diets containing modified distillers grains with solubles (MDGS) on feedlot performance (Feedlot Experiment), as well as digestibility, ruminal pH, and ruminal fermentation characteristics (Digestibility Experiment). The feedlot experiment utilized 72 Angus steers (392 ± 46.3 kg initial body weight) which were randomly assigned to 1 of 12 pens, 3 pens per treatment, to evaluate feedlot performance and carcass characteristics. Dietary treatments were 1) control; 10% roughage, 2) 12% roughage, 3) 14% roughage, and 4) 16% roughage. The digestibility experiment used four ruminally and duodenally cannulated steers (393 ± …

2022 Commencement Ceremonies For Nova Southeastern University, Nova Southeastern University

NSU Commencement Programs

No abstract provided.

Office Of Equity And Inclusion Newsletter - May 2022, Office Of Equity And Inclusion, East Tennessee State University

Office of Equity and Inclusion Newsletters

No abstract provided.

Biohelm Smart Hockey Helmet: A Conceptual Wearable System For Protecting And Empowering Female Athletes, Anthony Parrucci

Theses

Women’s ice hockey is one of the fastest growing sports in the world and needs the most articles of protective equipment. At the National Collegiate Athletic Association (NCAA) level, not only do these athletes need to adapt to team issued equipment that rarely fits comfortably or safely but must also consider the important facets that impact overall performance. The main objective of this project is to promote inclusivity while protecting, empowering and educating athletes in an ethical, noninvasive manner to positively impact the culture of women’s sports. Overexertion at the NCAA level increases exponentially due to the intense training and …

Therapeutic Efficacy Of Zinc In The Treatment Of Covid-19 Patients: A Systematic Review, Olivia Schimmel, Varna Taranikanti

Posters

INTRODUCTION
Novel therapeutic interventions are of utmost importance to alleviate the clinical symptoms caused by inflammation in COVID-19 patients. The beneficial role of zinc has been suggested due to its ability to mitigate the effects of the inflammatory cascade. Hence it has been hypothesized that patients with zinc deficiency may benefit symptomatically from treatment with zinc. The primary goal of this systematic review of randomized controlled trials conducted between February and March 2021 is to determine the efficacy of zinc as a treatment for COVID-19 infection.

Dietary Supplement Use Among Brca1/2 Mutation Carriers, Ryan Rogers, Tara Ramgarajan, Virginia Uhley, Kristina Ivan, Dana Zakalik

Posters

INTRODUCTION
Women who carry BRCA1/2 mutations are at significantly increased risk of breast, ovarian, pancreatic and other cancer. Little is known regarding the use of dietary supplements among women harboring BRCA1/2 mutations. This study aims to characterize the utilization of and attitudes toward dietary supplement use in women who carry BRCA1/2 mutations.

Generational Harmony Saves The World: How The Power Of Generation Theory, Gen Z Youth, And Activism Can Mitigate The Climate Crisis, Ryan Hill

Undergraduate Scholarship and Creative Works

This paper explores generations as a concept for understanding and explaining the relationship between major sociohistorical events and societal members, posits generation succession as a way in which long-term social change occurs, compares and contrasts the perceptions of the major generations (Baby Boomers, Gen X, Millennials) created by popular media and scholarly research, illuminates characterizations of the youngest and still-emerging Gen Z, discusses what major sociohistorical events during the time of their adolescence have folded Gen Z into a distinct group with a common generational consciousness, outlines how anthropogenic climate change is a real phenomenon with harmful consequences already affecting …