Digital Commons Network^™

Utilization Of Radiation Therapy And Predictors Of Noncompliance Among Syrian Refugees In Turkey, Tugce Kutuk

All Publications

Background: Access to cancer care is a problem that continues to plague refugees displaced from their home countries. The turbulent political crisis in Syria, which has led to millions of refugees seeking asylum in Turkey, merits further attention. We aimed to study the rate of utilization of radiation therapy among Syrian refugees with cancer living in Turkey in an attempt to identify the contributing factors predictive of non-compliance with prescribed RT.

Methods: In this retrospective review of 14 institutional databases, Syrian refugee patients in Turkey with a cancer diagnosis from January 2015 to December 2019 who were treated with RT …

How Algorithm-Assisted Decision Making Is Influencing Environmental Law And Climate Adaptation, Sonya Ziaja

All Faculty Scholarship

Algorithm-based decision tools in environmental law appear policy neutral
but embody bias and hidden values that affect equity and democracy. In effect,
algorithm-based tools are new fora for law and policymaking, distinct from
legislatures and courts. In turn, these tools influence the development and
implementation of environmental law and regulation. As a practical matter,
there is a pressing need to understand how these automated decision-making
tools interact with and influence law and policy. This Article begins this timely
and critical discussion.

After introducing the challenge of adapting water and energy systems to
climate change, this Article synthesizes prior multidisciplinary work …

The Development, Evaluation, And Pilot-Test Of A Nutrition Education Tool Kit At A Mobile Food Pantry In Virginia., Caitlin Swanson

Masters Theses, 2020-current

Objective: The purpose of this study was to develop, test and evaluate a nutrition education tool kit at a mobile food pantry (MFP) in rural Virginia.

Design: Cross-sectional, mixed methods approach using both quantitative and qualitative data to evaluate the effectiveness of a tool kit training at increasing participant self-efficacy, basic nutrition knowledge and perceived readiness to conduct a nutrition lesson with MFP guests. The ability for participants to translate the training into practice was also observed and documented.

Setting: Pilot tested on March 11^th 2020 at the Timberville Blue Ridge Area Food Bank MFP site.

Participants …

The Effect Of Creatine Supplementation On Body Composition And Total Body Water Measured By Multi-Frequency Bioelectrical Impedance, Emily A. Buck

Masters Theses, 2020-current

Background: Acute fluid ingestion causes an increase in estimated body fat percentage (BF%) measurements by single frequency (SF-BIA) and multi-frequency bioelectrical impedance (MF-BIA). However, it is unknown if MF-BIA accurately measures total body water (TBW) and BF% after chronic fluid retention. Creatine supplementation causes fluid retention, and resultant increases in TBW and body mass. Research is needed to determine if MF-BIA is capable of detecting fluid retention secondary to creatine supplementation. Methods: 13 male and 14 female subjects (18-22 y) completed one week of creatine monohydrate or maltodextrin supplementation at a dose of 0.3 g/kg body weight. Subjects completed pre-supplementation …

The Effect Of Dietary Nitrate Supplementation On Physical And Cognitive Performance During Load Carriage In Military Cadets, Nicholas C. Bordonie

Masters Theses, 2020-current

Purpose: The purpose of this study was to determine the effects of dietary nitrate supplementation on physical and cognitive performance during exercise conducted under heavy pack load in military cadets. Methods: Ten college-aged males (VO_2max 56.2 ± 3.7 ml/kg/min) consumed 140mL/d of concentrated beetroot juice (BRJ; containing 12.8 mmol of dietary nitrate) or a placebo (PL; flavor, color, energy, and texture-matched with no dietary nitrate) for six days preceding an exercise trial. The trial consisted of 45 min of constant-load exercise on a treadmill at 4.83 km/h and 1.5% grade, followed immediately by a 1.6-km time-trial completed at maximal …

“But For Those Of Us Who Live Here”: Performance Of Work And Community By Women Employed In Rural, Predominantly White, Small-Town Schools, Telena M. Turner

Masters Theses, 2020-current

Rural, small towns are incredibly complex cultural centers. Although rural places are consistently portrayed as unchanging, the operation of cultural and identity within these locations is consistently on the move. Using reflexive interviewing, poetic transcription, autoethnographic writing, this project (re)presents poems on community and identity from five women employed in schools in rural, mostly White, small towns in the Central Appalachian region. Analyzing the poems through concepts in performance studies and work on space and place, this project positions movement and change at the center of small towns and examines how notions of rural place and community are performed through …

A Review Of Dietary Monitoring Applications And Eating Disorder/Disordered Eating Symptomatology, Donald Mellott Jr.

Masters Theses, 2020-current

Eating disorders are among the deadliest mental illnesses in the United States. Given their high prevalence and low treatment rates, mitigating risk exposure is necessary for prevention. Dietary monitoring applications are highly popular self-monitoring tools that can inform dietary patterns and improve weight loss efficacy. However, they can also serve as a means for those with body preoccupation to restrict and possibly exacerbate disordered symptomatology. A literature search was conducted to identify research regarding the usage of dietary monitoring applications and eating disorder/disordered eating symptomatology. Twelve articles met inclusion criteria and are discussed in the review. An association between the …

Pilfering Passerines? Inter-Class Competition: A New Direction In Foraging Ecology, Shannon Gillen

Masters Theses, 2020-current

Life in the epigeal layer below leaf litterfall often goes unexplored. Shrews (Soricidae, 1910) have foraged in this microhabitat for millions of years, carving out an existence in harsh habitats around the world, ranging from the tropics to subarctic boreal tundra. Two shrew species that inhabit the Shenandoah Valley of Virginia, the least shrew (Cryptotis parva) and northern short-tailed shrew (Blarina brevicauda), were the focus of this study. Shrews make epigeal foraging trails while they continually forage for food, and caching is a way to save this food for times of low and sporadic food availability. …

The Effects Of A Carbohydrate Hydrogel Beverage On Gastrointestinal Symptoms And Running Performance In Comparison To Conventional Carbohydrate Beverages, Nicholas Minichiello

Masters Theses, 2020-current

PURPOSE: The utilization of hydrogel technology allows carbohydrate beverages to form a gel in the acidic environment of the stomach, potentially enhancing gastric emptying. However, few studies have researched the effects of these beverages on gastrointestinal (GI) tolerance and exercise performance; there is minimal data in a variety of exercise conditions and/or beverage ingestion rates. The purpose of the present study was to assess the effects of a 80 g/h of maltodextrin-fructose hydrogel (MF-H) beverage versus conventional carbohydrate sources on GI symptoms and running performance. METHODS: eight distance runners (26 ± 5 y; VO_2max = 65 ± 7 ml/kg/min) …

The Effect Of Intensity And Duration Of Verification Stages On The Efficacy Of Vo2max Testing, Andrew Foster

Masters Theses, 2020-current

Purpose: To determine if changing the length of the recovery stage influences the effectiveness, or ability to confirm maximal oxygen consumption (VO_2max), of the verification phase and if the initial intensity of the stage has an impact on its effectiveness. Methods: 27 subjects (20 males and 7 females) performed four separate VO_2max tests separated by at least 48 hours. For each initial graded exercise test, starting speed was 3.0 mph and increased by 0.5 mph every minute until 6.0 mph was reached. After this point, elevation was increased by 3.0% every minute until volitional exhaustion. VO_{2 …}

Does A Bout Of Acute Resistance Exercise Attenuate The Post-Prandial Lipemic Response To A High Fat Meal In 50-80 Year-Old Adults, Summer Simulcik

Masters Theses, 2020-current

Background: A single high-fat meal (HFM) is known to elevate blood lipid levels above what is normal, resulting in postprandial lipemia (PPL). Chronic hyperlipemia has been associated with increased risk for cardiovascular disease (CVD) and type-2 diabetes mellitus (T2DM) development. Current physical activity (PA) guidelines recommend at least one set of 8-12 repetitions of each exercise to attenuate this risk. Adults older than 50 (OF) years (y) are at an increased risk for cardiometabolic disease compared to younger adults (YA). Aerobic exercise (AE) performed in the pre-prandial period has been observed to attenuate PPL in both OF and YA. However, …

Urbanization Drives Changes In Avian Communities, Which Are Reflected In The Song Of A Vocal Mimic, Jaclyn Tolchin

Masters Theses, 2020-current

Urban landscapes present problems for wildlife including highly modified habitat, anthropogenic noise pollution, and competition for suitable habitat. These novel selection pressures can filter species present in urban habitats or result in changes to behavior. Recent studies show that some bird species sing differently (louder, higher pitch, faster) in noisier, urban areas compared to quieter, more rural areas, and that anthropogenic noise alone can exclude species. I investigated how the level of urbanization affects 1) bird species composition, and 2) the assemblage of species that a songbird mimics from the local bird community. I studied gray catbirds, Dumetella carolinensis, across …

Alcohol Impairs Immunometabolism And Promotes Naïve T Cell Differentiation To Pro-Inflammatory Th1 Cd4+ T Cells, Patrick M. Mcternan, Danielle E. Levitt, David A. Welsh, Liz Simon, Robert W. Siggins, Patricia E. Molina

School of Medicine Faculty Publications

CD4+ T cell differentiation to pro-inflammatory and immunosuppressive subsets depends on immunometabolism. Pro-inflammatory CD4+ subsets rely on glycolysis, while immunosuppressive Treg cells require functional mitochondria for their differentiation and function. Previous pre-clinical studies have shown that ethanol (EtOH) administration increases pro-inflammatory CD4+ T cell subsets; whether this shift in immunophenotype is linked to alterations in CD4+ T cell metabolism had not been previously examined. The objective of this study was to determine whether ethanol alters CD4+ immunometabolism, and whether this affects CD4+ T cell differentiation. Naïve human CD4+ T cells were plated on anti-CD3 coated plates with soluble anti-CD28, and …

Metabolic Profiling Of Firefighter Plasma Using 1h Nmr Platform Following Curcumin, Ketone Supplementations And Carbohydrate Restricted Diet Benefits For Oxidative Stress Suppression, Richard Eugene Baird

Theses and Dissertations

Occupational health surveys reported that first responders such as firefighters (FF) have some of the highest levels of cardiovascular disease in the nation from poor eating habits and lack of exercise. Three studies were established with goals to identify oxidative stress (OS) biomarkers and improve cardiovascular health for FF including: 1) a 28-day-carbohydrate restricted diet (CRD), 2) a heat-house search and clear protocol in personal protection equipment (PPE) plus curcumin supplementation, and 3) a treadmill exercise protocol in PPE with ketone salt supplementation. During those studies, stored blood plasma subsamples were evaluated for targeted antioxidants or untargeted metabolite concentration fluctuations …

Extended School Closure: The Perspectives From A Rural School Community, Ha Nguyen

Theses and Dissertations

The COVID-19 pandemic caused severe disruption to students worldwide, especially younger ones. This instrumental case study investigated how elementary students in a rural United States southeastern community experienced the sudden, extended closure of their school building facilities triggered by this health emergency. Multiple stakeholder perspectives were gathered through semi-structured interviews with the elementary school principal, three classroom teachers, three elementary-aged students, and three student family members, along with classroom observations as well as corresponding documents and artifacts. Interview commentaries and weekly reflective commentary journal entries were employed to address data validation and reliability issues. The findings demonstrate how the rural …

The Impact Of High- Vs. Low-Load Resistance Training On Measures Of Muscle Activation, Strength, Body Composition, And Hormonal Markers, Marissa Laina Bello

Theses and Dissertations

Resistance training has shifted towards a high- vs low-load training approach. Heavier loads are suggested to maximally recruit motor units and optimize strength adaptations, whereas lower loads stimulate hypertrophy. However, a majority of the research has not used a true strength range when assessing load. Therefore, the purpose of this investigation was to examine and determine significant differences in strength, body composition, and hormonal markers over nine weeks of high- or low-load resistance training. Secondary purposes of the current investigation were to assess and quantify training load for resistance training using sEMG sensor-embedded compression shorts. 17 recreationally-trained males were randomized …

Faculty Senate Agenda

Faculty Senate Agendas

No abstract provided.

Bromodomains In Human-Immunodeficiency Virus-Associated Neurocognitive Disorders: A Model Of Ferroptosis-Induced Neurodegeneration, Adonis Sfera, Karina G. Thomas, Christina V. Andronescu, Nyla Jafri, Dan O. Sfera, Sarvin Sasannia, Carlos Zapata-Martin Del Campo, Jose E. Campo Maldonado

School of Medicine Publications

Human immunodeficiency virus (HIV)-associated neurocognitive disorders (HAND) comprise a group of illnesses marked by memory and behavioral dysfunction that can occur in up to 50% of HIV patients despite adequate treatment with combination antiretroviral drugs. Iron dyshomeostasis exacerbates HIV-1 infection and plays a major role in Alzheimer’s disease pathogenesis. In addition, persons living with HIV demonstrate a high prevalence of neurodegenerative disorders, indicating that HAND provides a unique opportunity to study ferroptosis in these conditions. Both HIV and combination antiretroviral drugs increase the risk of ferroptosis by augmenting ferritin autophagy at the lysosomal level. As many viruses and their proteins …

Induced Spawning Of Captive Tripletail Lobotes Surinamensis, Nicholas Adams

Master's Theses

The Tripletail, Lobotes surinamensis, is an emerging candidate species for U.S. marine aquaculture. This work aimed to address two bottlenecks for hatchery production of the species by developing a hormonal induction protocol to obtain fertile spawns from captive brooders and a method for sex identification of candidate brooders.

Single pairs selected among a captive-held broodstock conditioned under a natural photothermal cycle were induced with one of five treatments (n = 5 or 6 replicates per treatment). Control (no hormone) and hCG (1,100 IU.kg^-1 for females, 550 IU.kg^-1 for males) pairs did not spawn. Pairs treated with GnRHa …

Efficacy Of Audio-Visual Aided Instruction For Improving Students’ Interest And Achievement In Stem Subjects: Implications For Library Practice, William Onu, Anthony Uchechukwu Uzoigwe, Fakolade Benjamin Ayodele, Oluwatoyin Comfort Oluwatosin, Deborah Dele

Library Philosophy and Practice (e-journal)

Considering that science and technology is key to comprehending and providing solution to problems plaguing humanity, STEM education is vital to a great future. With this being so, students are encouraged to develop skills and competencies needed to become educators, innovators, researchers, and leaders in different STEM domains, who can solve the most pressing problems facing humanity, now and in the future. However, there seem to be shortage of interest from students to pursue STEM careers. In a bid contribute to raising the level of interest in STEM subjects, this study, conducted in Nsukka education zone of Enugu state, sought …

Wernicke Encephalopathy Following Gastric Bypass: A Case Report, Sarah Glisan, Nazim Khan

Research Day

Bariatric surgery is used as a treatment for morbid obesity and often results in rapid weight loss. This procedure has been associated with postoperative nutritional deficiencies. Neurological complications due to nutritional deficiencies include Wernicke encephalopathy, a disorder that affects the central and peripheral nervous system due to thiamine (vitamin B1) deficiency. Wernicke encephalopathy can lead to irreversible consequences if not treated early. Here, we present a case of a 40-year-old woman that developed Wernicke encephalopathy two months after gastric bypass surgery, with additional findings of flat affect and concurrent polyradiculopathy. Her diagnosis was delayed due to unique symptoms and an …

Adaptation Of The Conditioned Assessment Of Speech Production In Spanish, Alliete R. Alfano, Daniel Gonzalez, David J. Ertmer

Journal of Early Hearing Detection and Intervention

Purpose: The purpose of this article is to describe the adaptation of the Spanish adaptation of the CASP.

Method: The authors adapted each segment into Spanish, then had 41 participants complete a survey to determine if each adapted segment was representative of the Spanish phonologic system. Thirty-six children (half with typical hearing, half with hearing loss) completed the CASP in English and Spanish. Paired samples t-tests were run to compare English and Spanish CASP scores between children with hearing loss and those with typical hearing.

Results: All segments were adapted as needed into Spanish. There was no statistical difference between …

We Are ... Marshall, May 11, 2022, Office Of Marshall University Communication

We Are ... Marshall: the Newsletter for Marshall University 1999-2023

No abstract provided.

Development And Validation Of High-Resolution Melting Assays For The Detection Of Potentially Virulent Strains Of Escherichia Coli O103 And O121, Frank J. Velez, Joseph M. Bosilevac, Sabine Delannoy, Patrick Fach, Ravinder Nagpal, Prashant Singh

Roman L. Hruska U.S. Meat Animal Research Center: Reports

Virulent strains of Shiga toxin-producing Escherichia coli (STEC) serogroups O103 and O121 are considered adulterants in beef. Two high-resolution melting (HRM) real-time PCR assays were standardized for the specific detection and discrimination of potentially virulent and avirulent strains of E. coli O103 and O121. The O103 HRM assay offered the possibility to distinguish clearly STEC O103:H2 from STEC O103:H25. The two standardized assays were extensively validated using 215 pure culture strains, laboratory inoculated food samples, and naturally contaminated beef (n = 84) and pork (n = 84) enrichments collected from the red meat surveillance program. Both HRM assays showed 100% …

Spanish Culture Club, Emily Taylor

Honors Program: Expanded Learning Clubs

No abstract provided.

Clock-Linked Genes Underlie Seasonal Migratory Timing In A Diurnal Raptor, Christen M. Bossu, Julie A. Heath, Gregory S. Kaltenecker, Barbara Helm, Kristen C. Ruegg

Biology Faculty Publications and Presentations

Seasonal migration is a dynamic natural phenomenon that allows organisms to exploit favourable habitats across the annual cycle. While the morphological, physiological and behavioural changes associated with migratory behaviour are well characterized, the genetic basis of migration and its link to endogenous biological time-keeping pathways are poorly understood. Historically, genome-wide research has focused on genes of large effect, whereas many genes of small effect may work together to regulate complex traits like migratory behaviour. Here, we explicitly relax stringent outlier detection thresholds and, as a result, discover how multiple biological time-keeping genes are important to migratory timing in an iconic …

Surviving Future Pandemics: The Economic, Social, And Political Battle Against Climate Change And Infectious Diseases, Dayana Gonzalez

Student Theses 2015-Present

COVID-19 has been a rude wake-up call as it showed us how unprepared we are to fight off infectious diseases. This paper analyzes our political, social, and economic decisions to develop a plan against the future development of infectious diseases. Before the analysis, it is essential to understand that it is natural for infectious diseases to develop and spread; however, climate change has and will continue to exacerbate the number of diseases developed and spread. Chapter 1 provides data on how climate change has destroyed habitats and displaced millions of animals, forcing them to live under cramped conditions that have …

Using The Whole School, Whole Child, Whole Community Approach To Improve An Urban Early Learning Center Students’ Social, Emotional, And Physical Health And Wellness, Joelle Chateauneuf

Doctor of Nursing Practice Scholarly Projects

Background: Integrating school-based health education and models of healthy lifestyles in early childhood provides a foundation for lifelong health learning. Many chronic may be prevented or mitigated through early childhood health education. Early learning centers (ELCs) may be a perfect setting to enable young children to achieve their full potential.

Problem: In Boston, Massachusetts, there are differences in health experience across population groups. Children of color and lower socioeconomic challenges experience higher rates of chronic conditions.

Available Knowledge: Search of literature showed that school-based healthy lifestyle interventions improve healthy behaviors and can be taught to children as young as preschool. …

Health Equity & Obesity Management: An Improvement Project In A Federally Qualified Healthcare Center In Central Harlem, Brianna Bouchez

Doctor of Nursing Practice Scholarly Projects

Description of the problem: Obesity is a growing healthcare problem worldwide with extraordinary costs to the individual's health and the healthcare system. Individuals most affected by obesity include socioeconomically disadvantaged individuals, often with limited resources to seek specialized care.

Available knowledge: Various weight-loss interventions exist but access and success rates vary. Weight loss is often modest and additional factors such as social determinants of health, health literacy, and patient motivation are all factors important to the success of an intervention.

Specific Aims: The purpose of this quality improvement project was to improve self-regulatory weight loss behaviors and increase weight loss …

Mapping The Covid-19 Pandemic In Staten Island, Vincenzo Mezzio

Student Theses

COVID-19 has had diverging effects in New York City. Out of the five boroughs, Staten Island has one of the largest percentages of COVID-19 cases relative to population. This research examines key social and spatial factors that contribute to the increase in COVID-19 cases in Staten Island). It asks: Which parts of Staten Island have higher rates of transmission of COVID-19? Which parts of the borough have higher population who are more vulnerable to COVID-19? What is the relationship between the location of vaccination centers with the rates of COVID-19 cases? Using Geographic Information Systems (GIS), this research examines the …