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Articles 3061 - 3090 of 10517
Full-Text Articles in Entire DC Network
Effects Of Excessive Soil Phosphorus Accumulation On Loblolly Pine (Pinus Taeda L.) Seedlings, Hannah C. Bays
Effects Of Excessive Soil Phosphorus Accumulation On Loblolly Pine (Pinus Taeda L.) Seedlings, Hannah C. Bays
Electronic Theses and Dissertations
Many landowners in East Texas apply poultry litter to pastures as a source of nitrogen (N) for forage crops. After many years of repeated poultry litter application, soils can accumulate extremely high extractable phosphorus (P) concentrations, sometimes over 1000 mg kg-1 of plant available P. Landowners report the conversion of these pastures to loblolly pine (Pinus taeda L.) plantations is often problematic, with poor seedling survival and abnormal tree growth. This study was conducted to assess the effects of excessive soil phosphorus on loblolly pine seedlings. An outdoor pot study was conducted using bare root seedlings and triple …
Implementing Food Pantry Nutrition Policies: Perspectives From The Field, Jessica Vincent
Implementing Food Pantry Nutrition Policies: Perspectives From The Field, Jessica Vincent
Graduate Theses and Dissertations
The charitable food system includes food pantries and are often used by individuals and households who are food insecure (Kuhns & Norotny, 2021; Seligman & Berkowitz, 2019; Sangye, 2013). Adults with any level of food insecurity have a 43% to 53% greater risk of developing a chronic disease than those who are food secure. Those who are food secure have a 37% risk of developing a chronic disease (Gregory & Coleman-Jenson, 2017). For this reason, efforts are being made from state and federal levels to focus on nutrition security, rather than only food security, by increasing the percentage of nutrient …
Chondronecrosis With Osteomyelitis In Broilers: Bacterial Species Involvement And Influence Of Probiotics And Synbiotics, Amer Abdullah Hasan
Chondronecrosis With Osteomyelitis In Broilers: Bacterial Species Involvement And Influence Of Probiotics And Synbiotics, Amer Abdullah Hasan
Graduate Theses and Dissertations
Since 1945, the market for broiler production has evolved from a collection of smallholder poultry farms into an industry worth billions of dollars. Poultry production has not gone without challenges. Lameness in young broilers is presently a serious issue in the poultry industry for reasons of animal health and welfare, as well as significant lost production and revenue. Bacterial chondronecrosis with osteomyelitis (BCO) is a major form of lameness in broilers. This dissertation contains information about (i) the influence of Staphylococcus agnetis, Staphylococcus saprophyticus, Staphylococcus epidermidis and Enterococcus faecalis on inducing BCO lameness, (ii) evaluation of of probiotics for reducing …
Beyond Nutrition: Three Essays On The Effects Of Food Processing And Sustainability Labeling On Consumer Perceptions And Evaluations, Garrett J. Rybak
Beyond Nutrition: Three Essays On The Effects Of Food Processing And Sustainability Labeling On Consumer Perceptions And Evaluations, Garrett J. Rybak
Graduate Theses and Dissertations
Recent consumer trends reveal increasing demand for greater product transparency including how products are processed, the types of ingredients used, and the impact on the environment. As a result, food marketers often use a combination of processing, nutrient content, and/or sustainability claims to convey specific information to consumers. Considering these developments, several questions arise about how these claims affect consumer evaluations of healthfulness, sustainability, disease risk, and intent to purchase while considering the unregulated and regulated nature of many of these claims.
In Essay One, we extend our understanding of consumer responses to package claims by comparing the direct and …
Intestinal Microbiota Analysis Of Broiler Chickens Under Necrotic Enteritis Challenge And Tributyrin Supplementation, Taylor Nicole Mckinney
Intestinal Microbiota Analysis Of Broiler Chickens Under Necrotic Enteritis Challenge And Tributyrin Supplementation, Taylor Nicole Mckinney
Graduate Theses and Dissertations
Poultry is a staple protein source for most of the planet. Until recently, antibiotic growth promoters (AGPs) were used to prevent illnesses in commercial chicken production. Currently, this is not possible due to regulations and consumer concern, but without such a preventative, diseases like necrotic enteritis (NE) have reemerged, posing a threat to bird health, and ultimately, our food source. Necrotic enteritis is a severe gastrointestinal disease caused by the gram-positive pathogen, Clostridium perfringens. Clinical features of this disease are diarrhea, intestinal lesions, and death, with a high transmission rate. In a subclinical form, growth performance is diminished and is …
Investigating Hops Production In Arkansas To Support Specialty Crop Growth, James Oliver Mcclellan
Investigating Hops Production In Arkansas To Support Specialty Crop Growth, James Oliver Mcclellan
Graduate Theses and Dissertations
The hop plant (Humulus lupulus L.) is a perennial, climbing species within the Cannabaceae family that produces cones used for brewing. Hops are grown worldwide. In the United States most hops production occurs in the Pacific Northwest, but growth in the craft beer industry is driving efforts for hops production in other U.S. regions. Recommendations on hops cultivar suitability, fertility, and management are needed for the U.S. mid-south region. Objectives of this research on Arkansas-grown hops were to 1) assess the impact of cultivar and fertility rate on plant and cone attributes of six cultivars of Arkansas-grown hops and 2) …
The Relationship Between Psychosocial Factors And Food Waste-Related Behaviors Among College Students, Kacy Raquel Wright
The Relationship Between Psychosocial Factors And Food Waste-Related Behaviors Among College Students, Kacy Raquel Wright
Graduate Theses and Dissertations
Food waste is a significant environmental, economic, and social issue, with younger consumers as the most significant contributors. Specific behaviors, like over-purchasing food and misusing date labels, result from a complex interaction between social and psychological factors, which influence food waste among this demographic. The purpose of this study was to identify the psychosocial factors influencing food waste behaviors among college students at the University of Arkansas. Guided by the Theory of Planned Behavior, this study utilized online and face-to-face quantitative surveys, distributed to students enrolled at the University of Arkansas in the spring of 2022. Demographics, attitudes, subjective norms, …
Identification Of Genomic, Proteomic, And Metabolomic Signatures Associated With Pulmonary Hypertension Syndrome In Broilers, Duaa Almansaf
Identification Of Genomic, Proteomic, And Metabolomic Signatures Associated With Pulmonary Hypertension Syndrome In Broilers, Duaa Almansaf
Graduate Theses and Dissertations
The present dissertation contains a collection of studies that examine the genomic, proteomic, and metabolomic association to pulmonary hypertension or ascites phenotype in fast-growing broilers. Pulmonary hypertension is a multifactorial metabolic disease influenced by physiological, environmental, and nutritional factors. It is characterized by a number of structural changes including, thrombosis and adverse pulmonary vascular remodeling. Thus, the atrial pressure is increased, and the right ventricle becomes hypertrophied, resulting in heart failure and the death of the bird. Pulmonary hypertension or ascites is a global problem that has negatively impacted the economy. The increased mortality rate of broilers (25%) is estimated …
Effect Of Sensory Additives On Sow Lactation Performance, Subsequent Reproductive Performance, And Nursey Pig Performance, Nathan E. Davis
Effect Of Sensory Additives On Sow Lactation Performance, Subsequent Reproductive Performance, And Nursey Pig Performance, Nathan E. Davis
Graduate Theses and Dissertations
Maximizing nutrient intake during lactation is vital to sow performance as well as litter performance. The aim of these studies was to evaluate the impact of a sensory additive on sow lactation performance and nursery pig performance. Five groups of sows were farrowed, three during winter (October, December and January) and two during summer months (June, July, August). Sows were weighed, and back fat depth was measured, at 110 d of gestation prior to entering the lactation room, and again at weaning. The sows were blocked by parity, and then allotted by BW at d 110 to Control or 0.075% …
Conspicuous Asceticism: Collapsing Consumers' Hungry Ghosts, Ash Zareian
Conspicuous Asceticism: Collapsing Consumers' Hungry Ghosts, Ash Zareian
Theses and Dissertations
The author investigates an emerging construct called conspicuous asceticism expositioned from a narcissism-centric view. The understanding of this construct is approached by drawing an idiomatic semantic parallel in opposition to conspicuous consumption and by utilizing its current theoretical framework of narcissism. Moreover, this paper seeks to extend conspicuous consumption’s theoretical framework as synonymous with the construct of compulsive consumption. Furthermore, I illustrate that consumers must transcend narcissism through engaging in treatment modalities requisite to operationalize a pioneering effort in which consumers can engage in marketing campaign efforts to advertise conspicuous ascetic contexts. This dissertation gleans from extant literature in sociology, …
Evaluation Of The Feeding Value Of Proso Millet In Growing-Finishing Diets For Pigs And Effects Of Feed Ingredients And Medium-Chain Fatty Acids On Porcine Reproductive And Respiratory Syndrome Virus (Prrsv) Survivability, Khang Nguyen
Department of Animal Science: Dissertations, Theses, and Student Research
The objective of the project were to: 1) evaluate the feeding value of proso millet as a potential substitute for corn in corn-soybean meal-based diets for pigs; and 2) investigate the relationship between feed ingredients and virus survivability, followed by examining feed additive candidates that could mitigate the risk of transmission of viral pathogens.
In Exp. 1, 36 barrows were fed 1 of 4 dietary treatments, including: Diet 1, corn-soybean meal-based (control), and Diets 2, 3, and 4 had proso millet replacing 33%, 67%, and 100% of corn in the control diet, respectively. During Phase 3, pigs consuming the proso …
Impact Of Increasing Level Of Milk Production On Cow And Calf Behavior And Performance In The Nebraska Sandhills, Selby L. Boerman
Impact Of Increasing Level Of Milk Production On Cow And Calf Behavior And Performance In The Nebraska Sandhills, Selby L. Boerman
Department of Animal Science: Dissertations, Theses, and Student Research
Selection for increased milk production across the United States has resulted in variable cow and calf production responses. Better understanding of calf nursing and grazing behaviors may provide opportunities to help estimate how milk and grazed forage intake influence variability in calf performance. In a 2-yr study, cow-calf pairs (n = 65) were equipped with neck collars containing global positioning system (GPS) units to validate the efficacy of high-frequency GPS data to accurately identify calf nursing events and grazing behavior. Data were collected during 3-wk tracking periods during early lactation (calf age 65.4 ± 10.0 d; EARLY) and late …
Using Strategic Supplementation To Enhance Cow/Calf Productivity In Summer Calving Herds In The Nebraska Sandhills, Nicole M. Woita
Using Strategic Supplementation To Enhance Cow/Calf Productivity In Summer Calving Herds In The Nebraska Sandhills, Nicole M. Woita
Department of Animal Science: Dissertations, Theses, and Student Research
Young range beef cows consuming low-quality forage may result in an imbalance of energy and metabolizable protein, which can negatively affect the nutrient status of the cow and reproductive performance. In a 2-yr study conducted at Gudmundsen Sandhills Laboratory near Whitman, NE, 2- and 3-yr-old May-calving range cows (n = 181) grazing native range were individually supplemented daily with one of four supplements: 1) mineral with a target intake of 113 g/d (MIN), 2) MIN with 200 mg per head of Rumensin to with a target intake of 113 g/d (RUM), 3) MIN with a 226 g/d of high …
Investigating Bacterial Community Composition And Antimicrobial Resistance Genes In Beef Cattle, Arena E. See
Investigating Bacterial Community Composition And Antimicrobial Resistance Genes In Beef Cattle, Arena E. See
Department of Animal Science: Dissertations, Theses, and Student Research
While antibiotics have been critical over the last decade for curbing infectious diseases, they have contributed to the rise of antimicrobial resistance (AMR). Infections resulting from antimicrobial-resistant pathogens are correlated with severe morbidity, mortality, and healthcare costs. With the increasing concerns regarding AMR and its emergence, it is paramount to understand not only the effects of antibiotics on microbial community and diversity, but also to develop a novel tool that gives us a better understanding of the spread and functional traits of AMR genes.
To this end, rumen, fecal, and pen surface samples were collected from 72 animals at United …
Shared Decision Making In Health Care: Theoretical Perspectives For Why It Works And For Whom., Ken Resnicow, Delwyn Catley, Kathy Goggin, Sarah Hawley, Geoffrey C. Williams
Shared Decision Making In Health Care: Theoretical Perspectives For Why It Works And For Whom., Ken Resnicow, Delwyn Catley, Kathy Goggin, Sarah Hawley, Geoffrey C. Williams
Manuscripts, Articles, Book Chapters and Other Papers
Applying both theoretical perspectives and empirical evidence, we address 2 key questions regarding shared decision making (SDM): 1) When should SDM be more patient driven, and when should it be more provider driven? and 2) Should health care providers match their SDM style/strategy to patient needs and preferences? Self-determination theory, for example, posits a distinction between autonomy and independence. A patient may autonomously seek their health care provider's input and guidance, perhaps due to low perceived competence, low coping resources, or high emotional arousal. Given their need state, they may autonomously require nonindependence. In this case, it may be more …
Ablation Of Long Noncoding Rna Malat1 Activates Antioxidant Pathway And Alleviates Sepsis In Mice, Jingshu Chen, Shu Tang, Sui Ke, James J Cai, Daniel Osorio, Andrei Golovko, Benjamin Morpurgo, Shaodong Guo, Yuxiang Sun, Melanie Winkle, George A Calin, Yanan Tian
Ablation Of Long Noncoding Rna Malat1 Activates Antioxidant Pathway And Alleviates Sepsis In Mice, Jingshu Chen, Shu Tang, Sui Ke, James J Cai, Daniel Osorio, Andrei Golovko, Benjamin Morpurgo, Shaodong Guo, Yuxiang Sun, Melanie Winkle, George A Calin, Yanan Tian
Faculty, Staff and Student Publications
The metastasis-associated lung adenocarcinoma transcript1 (MALAT1) is a long noncoding RNA (lncRNA) and is known for its role in cancer development and prognosis. In this study, we report that MALAT1 plays an important role in regulating acute inflammatory responses in sepsis. In patient samples, MALAT1 expression was positively correlated with severity of sepsis. In cultured macrophages, LPS treatment significantly induced MALAT1 expression, while genetic ablation of MALAT1 greatly reduced proinflammatory cytokine levels. Furthermore, MALAT1-ablated mice had significantly increased survival rates in cecal ligation and puncture (CLP)-induced sepsis and LPS-induced endotoxemia. One novel and salient feature of MALAT1-ablated mice is greatly …
Unilateral Radiation Therapy For Tonsillar Cancer: Treatment Outcomes In The Era Of Human Papillomavirus, Positron-Emission Tomography, And Intensity Modulated Radiation Therapy, Nicolette Taku, Gregory Chronowski, G Brandon Gunn, William H Morrison, Neil D Gross, Amy C Moreno, Renata Ferrarotto, Steven J Frank, C David Fuller, Ryan P Goepfert, Jack Phan, Stephen Y Lai, Jay P Reddy, David I Rosenthal, Adam S Garden
Unilateral Radiation Therapy For Tonsillar Cancer: Treatment Outcomes In The Era Of Human Papillomavirus, Positron-Emission Tomography, And Intensity Modulated Radiation Therapy, Nicolette Taku, Gregory Chronowski, G Brandon Gunn, William H Morrison, Neil D Gross, Amy C Moreno, Renata Ferrarotto, Steven J Frank, C David Fuller, Ryan P Goepfert, Jack Phan, Stephen Y Lai, Jay P Reddy, David I Rosenthal, Adam S Garden
Faculty, Staff and Student Publications
Purpose: The goal of this study was to evaluate disease, survival, and toxic effects after unilateral radiation therapy treatment for tonsillar cancer.
Methods and materials: A retrospective study was performed of patients treated at our institution within the period from 2000 to 2018. Summary statistics were used to assess the cohort by patient characteristics and treatments delivered. The Kaplan-Meier method was used to determine survival outcomes.
Results: The cohort comprised 403 patients, including 343 (85%) with clinical and/or radiographic evidence of ipsilateral cervical nodal disease and 181 (45%) with multiple involved nodes. Human papillomavirus was detected in 294 (73%) tumors. …
Insulin Resistance In Depression: A Large Meta-Analysis Of Metabolic Parameters And Variation, Brisa S Fernandes, Estela Salagre, Nitesh Enduru, Iria Grande, Eduard Vieta, Zhongming Zhao
Insulin Resistance In Depression: A Large Meta-Analysis Of Metabolic Parameters And Variation, Brisa S Fernandes, Estela Salagre, Nitesh Enduru, Iria Grande, Eduard Vieta, Zhongming Zhao
Faculty, Staff and Student Publications
Increased insulin resistance is recognized in psychiatric disorders, such as schizophrenia and bipolar disorder, but its occurrence in depression is less clear. Our aims were to verify if insulin resistance is altered in depression, to test the metabolic subgroup hypothesis of depression and if there are changes with antidepressants. Inclusion criteria were studies including adult subjects with depression and either a control group or follow-up after treatment with antidepressants, and assessing fasting insulin or glucose levels or the Homeostatic Model Assessment for Insulin Resistance (HOMA-IR) index. Seventy studies with 240,704 participants were included. Both insulin levels and the HOMA-IR index …
The Geriatric Nutritional Risk Index As A Predictor Of Complications In Geriatric Trauma Patients: Author Reply In Response To: “The Admission Serum Level Of Albumin Cannot Thoroughly Represent The Nutritional Status Of Trauma Patients”, Heather R Kregel, Patrick B Murphy, Mina Attia, David E Meyer, Rachel S Morris, Ezenwa C Onyema, Sasha D Adams, Charles E Wade, John A Harvin, Lillian S Kao, Thaddeus J Puzio
The Geriatric Nutritional Risk Index As A Predictor Of Complications In Geriatric Trauma Patients: Author Reply In Response To: “The Admission Serum Level Of Albumin Cannot Thoroughly Represent The Nutritional Status Of Trauma Patients”, Heather R Kregel, Patrick B Murphy, Mina Attia, David E Meyer, Rachel S Morris, Ezenwa C Onyema, Sasha D Adams, Charles E Wade, John A Harvin, Lillian S Kao, Thaddeus J Puzio
Faculty, Staff and Student Publications
BACKGROUND: Malnutrition is associated with increased morbidity and mortality after trauma. The Geriatric Nutritional Risk Index (GNRI) is a validated scoring system used to predict the risk of complications related to malnutrition in nontrauma patients. We hypothesized that GNRI is predictive of worse outcomes in geriatric trauma patients.
METHODS: This was a single-center retrospective study of trauma patients 65 years or older admitted in 2019. Geriatric Nutritional Risk Index was calculated based on admission albumin level and ratio of actual body weight to ideal body weight. Groups were defined as major risk (GNRI98). The primary outcome was mortality. Secondary outcomes …
Strategy For Generating Blinded Evidence For Single-Arm Trials With External Controls Using Expert Review Of Home Video, Bharti Manwani, Carson Finger, Lynda Lisabeth
Strategy For Generating Blinded Evidence For Single-Arm Trials With External Controls Using Expert Review Of Home Video, Bharti Manwani, Carson Finger, Lynda Lisabeth
Faculty, Staff and Student Publications
Stroke risk and prevalence increase with advanced age and women tend to be older than men at the time of their first stroke. Advanced age in women confers unique stroke risks that are beyond reproductive factors. Previous reviews and guidelines have largely focused on risk factors specific to women, with a predominant focus on reproductive factors and, therefore, younger to middle-aged women. This review aims to specifically describe stroke risk factors in elderly women, the population of women where the majority of strokes occur, with a focus on atrial fibrillation, hormone therapy, psychosocial risk factors, and cognitive impairment. Our review …
Characterization Of Kinases And Hypothetical Proteins In The Entamoeba Species, Heather Andrews Walters
Characterization Of Kinases And Hypothetical Proteins In The Entamoeba Species, Heather Andrews Walters
All Dissertations
Entamoeba histolytica is a protozoan parasite that causes amebic dysentery and amoebic liver abscess. This pathogen possesses a two-stage life cycle consisting of an environmentally stable latent cyst and a pathogenic amoeboid trophozoite. Since infection is acquired by ingestion of cysts from contaminated food and water, this parasite is prevalent in underdeveloped countries. A reptilian pathogen, Entamoeba invadens, which can encyst in culture, has long-served as a surrogate to study stage conversion. Much remains unclear about stage conversion and the stress response in these parasites and current treatments for amoebiasis are lacking, as they cause severe side effects. Ultimately …
Development Of A Reverse Engineered, Parameterized, And Structurally Validated Computational Model To Identify Design Parameters That Influence American Football Faceguard Performance, William Ferriell
All Dissertations
Traumatic brain injury (TBI) continues to have the greatest incidence among athletes participating in American football. The headgear design research community has focused on developing accurate computational and experimental analysis techniques to better assess the ability of headgear technology to attenuate impacts and protect athletes from TBI. Despite efforts to innovate the headgear system, minimal progress has been made to innovate the faceguard. Although the faceguard is not the primary component of the headgear system that contributes to impact attenuation, faceguard performance metrics, such as weight, structural stiffness, and visual field occlusions, have been linked to athlete safety. To improve …
Evaluation Of Turkish Delight Prepared With Pigments And Essential Oils Extracted From Clementine (Citrus Clementine) Peels As Natural Antioxidants, Eman A. Ibrahim, Azza A. Omran, Zeinab A. Salama
Evaluation Of Turkish Delight Prepared With Pigments And Essential Oils Extracted From Clementine (Citrus Clementine) Peels As Natural Antioxidants, Eman A. Ibrahim, Azza A. Omran, Zeinab A. Salama
Baghdad Science Journal
This experiment presented essential oils by GC/MS, pigment content, and their antioxidant activities as well as sensory evaluation of delight samples. Limonene (66.88%) was the most prevalent yield. The peels of clementine had DPPH and ABT Scavenging activity. All levels of pigment extract had better scores for all sensory values and recorded acceptable scores in terms of appearance, color, aroma, and overall acceptability compared to control delight. Besides, delight samples containing 15 mg astaxanthin pigment extract showed maximum sensory scores compared to other samples and control delight. On the other hand, the product was less acceptable to the panelists compared …
The Effect Of White Rot Fungus (Ganoderma Sp) As Decomposers On Composting Using Combination Of Cattle Feces And Water Hyacinth (Eichhornia Crassipes) As Organic Matter, Muhammad Irfan Said, Effendi Abustam, Sitti Nurani Sirajuddin, Jamila, Tensi, Abdel Razzaq Al Tawaha, Abdel Rahman M. Al Tawaha
The Effect Of White Rot Fungus (Ganoderma Sp) As Decomposers On Composting Using Combination Of Cattle Feces And Water Hyacinth (Eichhornia Crassipes) As Organic Matter, Muhammad Irfan Said, Effendi Abustam, Sitti Nurani Sirajuddin, Jamila, Tensi, Abdel Razzaq Al Tawaha, Abdel Rahman M. Al Tawaha
Baghdad Science Journal
In Indonesia, cattle feces (CF) and water hyacinth (WH) plants are abundant but have not been widely revealed. The use of microorganisms as decomposers in the fermentation process has not been widely applied, so researchers are interested in studying further. This study was to evaluate the effect of the combination of CF with WH on composting by applying white-rot fungal (WRF) (Ganoderma sp) microorganism as a decomposer. A number of six types of treatment compared to R1(ratio of CF:WH)(25%:75%)+WRF; R2(ratio of CF:WH)(50%:50%)+WRF; R3(ratio of CF:WH)(75%:25%)+WRF; R4(ratio of CF:WH)(25%:75%) without WRF; R5(ratio of CF:WH)(50%:50%) without WRF; R6(ratio of CF:WH)(25%:75%) without WRF. …
Moment-To-Moment Observation Of Parental Media Use And Parent-Child Interaction: Quality And Media Multitasking, Lisa Linder, Brandon T. Mcdaniel Phd, Heather Jaffe
Moment-To-Moment Observation Of Parental Media Use And Parent-Child Interaction: Quality And Media Multitasking, Lisa Linder, Brandon T. Mcdaniel Phd, Heather Jaffe
Health Services and Informatics Research
Mobile media proliferation throughout society has infused and complicated environments that formerly were interaction rich (e.g., waiting rooms, restaurants, and playgrounds) with the presence of smart devices. Ethnographic studies have indicated that parental use negatively impacts parent-child interaction quality. The current study reviews and expands on previous research through observing systematically parent-child interaction quality throughout the course of an entire meal (30-140 minutes). Utilizing five-minute intervals, across 93 parent-child dyads, we assessed both within- and between-person moment-to-moment changes in parenting quality (i.e., parental positivity, negativity, and engagement) in the context of parental media use. Between-person, only positivity appeared to decrease …
Water Temperature Effect On Hardness And Flexural Strength Of (Pmma/Tio2 Nps) For Dental Applications, Zaynab N.Rahseed Alraziqi
Water Temperature Effect On Hardness And Flexural Strength Of (Pmma/Tio2 Nps) For Dental Applications, Zaynab N.Rahseed Alraziqi
Baghdad Science Journal
PMMA (Poly methyl methacrylate) is considered one of the most commonly used materials in denture base fabrication due to its ideal properties. Although, a major problem with this resin is the frequent fractures due to heavy chewing forces which lead to early crack and fracture in clinical use. The addition of nanoparticles as filler performed in this study to enhance its selected mechanical properties. The Nano-additive effect investigated in normal circumstances and under a different temperature during water exposure. First, tests applied on the prepared samples at room temperature and then after exposure to water bath at (20, 40, 60) …
Keto Prescribed, Audra Hanners
Keto Prescribed, Audra Hanners
Sigma Foundation for Nursing Research Grant Reports
The purpose of this project, Keto Prescribed, was to implement research evidence of a ketogenic diet into clinical practice through a nurse practitioner (NP)-led interdisciplinary health coaching team approach and evaluate outcomes on CVD risk factors and health related quality of life in overweight, adult African American women. The primary objective of this project was to measure the improvement in Keto Prescribed participants physical CVD risk factors. Our second objective is to measure the improvement in health-related quality of life, both mental and physical health of Keto Prescribed participants. Our last objective is to measure the feasibility and acceptability of …
The Intricate Interplay Between Cancer Stem Cells And Cell-Of-Origin Of Cancer: Implications For Therapeutic Strategies, Luis Alberto Vega, Misu A Sanson, María Belén Cubria, Shrijana Regmi, Brittany J Shah, Samuel A Shelburne, Anthony R Flores
The Intricate Interplay Between Cancer Stem Cells And Cell-Of-Origin Of Cancer: Implications For Therapeutic Strategies, Luis Alberto Vega, Misu A Sanson, María Belén Cubria, Shrijana Regmi, Brittany J Shah, Samuel A Shelburne, Anthony R Flores
Faculty, Staff and Student Publications
Antimicrobial resistance-encoding mobile genetic elements (MGEs) may contribute to the disease potential of bacterial pathogens. We previously described the association of Group A Streptococcus (GAS) derived from invasive disease with increasingly frequent antimicrobial resistance (AMR). We hypothesized that a 65-kb AMR-encoding MGE (ICESpyM92), highly conserved among closely related emergent invasive emm92 GAS, contributes to GAS disease potential. Here, we provide evidence that a combination of ICESpyM92- and core genome-dependent differential gene expression (DGE) contributes to invasive disease phenotypes of emergent emm92 GAS. Using isogenic ICESpyM92 mutants generated in distinct emm92 genomic backgrounds, we determined the presence of ICESpyM92 enhances GAS …
Expanding Acta2 Genotypes With Corresponding Phenotypes Overlapping With Smooth Muscle Dysfunction Syndrome, Anita Kaw, Kaveeta Kaw, Ellen M Hostetler, Ana Beleza-Meireles, Adam Smith-Collins, Catherine Armstrong, Ingrid Scurr, Timothy Cotts, Rajani Aatre, Michael J Bamshad, Dawn Earl, Abraham Groner, Katherine Agre, Yehuda Raveh, Callie S Kwartler, Dianna M Milewicz
Expanding Acta2 Genotypes With Corresponding Phenotypes Overlapping With Smooth Muscle Dysfunction Syndrome, Anita Kaw, Kaveeta Kaw, Ellen M Hostetler, Ana Beleza-Meireles, Adam Smith-Collins, Catherine Armstrong, Ingrid Scurr, Timothy Cotts, Rajani Aatre, Michael J Bamshad, Dawn Earl, Abraham Groner, Katherine Agre, Yehuda Raveh, Callie S Kwartler, Dianna M Milewicz
Faculty, Staff and Student Publications
Pathogenic variants in ACTA2, encoding smooth muscle α-actin, predispose to thoracic aortic aneurysms and dissections. ACTA2 variants altering arginine 179 predispose to a more severe, multisystemic disease termed smooth muscle dysfunction syndrome (SMDS; OMIM 613834). Vascular complications of SMDS include patent ductus arteriosus (PDA) or aortopulmonary window, early-onset thoracic aortic disease (TAD), moyamoya-like cerebrovascular disease, and primary pulmonary hypertension. Patients also have dysfunction of other smooth muscle-dependent systems, including congenital mydriasis, hypotonic bladder, and gut hypoperistalsis. Here, we describe five patients with novel heterozygous ACTA2 missense variants, p.Arg179Gly, p.Met46Arg, p.Thr204Ile, p.Arg39Cys, and p.Ile66Asn, who have clinical complications that align or …
Adipose Tissue-Specific Ablation Of Ces1d Causes Metabolic Dysregulation In Mice, Gang Li, Xin Li, Li Yang, Shuyue Wang, Yulin Dai, Baharan Fekry, Lucas Veillon, Lin Tan, Rebecca Berdeaux, Kristin Eckel-Mahan, Philip L Lorenzi, Zhongming Zhao, Richard Lehner, Kai Sun
Adipose Tissue-Specific Ablation Of Ces1d Causes Metabolic Dysregulation In Mice, Gang Li, Xin Li, Li Yang, Shuyue Wang, Yulin Dai, Baharan Fekry, Lucas Veillon, Lin Tan, Rebecca Berdeaux, Kristin Eckel-Mahan, Philip L Lorenzi, Zhongming Zhao, Richard Lehner, Kai Sun
Faculty, Staff and Student Publications
Carboxylesterase 1d (Ces1d) is a crucial enzyme with a wide range of activities in multiple tissues. It has been reported to localize predominantly in ER. Here, we found that Ces1d levels are significantly increased in obese patients with type 2 diabetes. Intriguingly, a high level of Ces1d translocates onto lipid droplets where it digests the lipids to produce a unique set of fatty acids. We further revealed that adipose tissue-specific Ces1d knock-out (FKO) mice gained more body weight with increased fat mass during a high fat-diet challenge. The FKO mice exhibited impaired glucose and lipid metabolism and developed exacerbated liver …