Digital Commons Network^™

The Impact Of Internal And External Factors On Female Enrollment In Vocational Training Institutes In The United Arab Emirates: A Phenomenological Qualitative Study, Saada Mubarak Amro

Dissertations

Educational institutes around the world and vocational training institutes, in particular, are concerned with students’ participation and enrollment rates. Great emphasis is placed on the vocational sector and its role in establishing a knowledge-based economy in the United Arab Emirates (UAE), as articulated in the UAE Vision 2021, its economic foresight 2030, and in the recent 50th-anniversary statement released in 2019 by HH Mohammed Rashed Al Maktoum. The importance of this sector is its significance in diversifying the economy, providing employment, and equipping both employed and unemployed nationals with the vocational skills required by local and international markets and industries. …

Impacts Of Intermediate And Long-Term Vitamin D Deficiency On The Murine Gastric Epithelial Cells And Acid Secretion, Shaima Raji Sirajudeen

Dissertations

The biological functions of vitamin D (VD) are diverse. It influences immunological response, cell proliferation and differentiation, and calcium homeostasis. However, over one billion people globally are VD deficient. The VD receptors, VDR and PDIA3, mediate the biological activities of VD. Studies on the biological roles of VD are numerous but very little on the stomach. The stomach is divided into three main parts – forestomach, corpus and antrum. Gastric glands, which make up the functional units of the stomach, are made up of numerous cell lineages and are located in the corpus and antrum, which are the glandular parts …

Gestational Diabetes Mellitus Screening, Diagnosis And Knowledge In The United Arab Emirates, Maryam Mohammed Bashir

Dissertations

Gestational diabetes mellitus (GDM) is a significant public health problem with short- and long-term consequences. If undiagnosed and untreated, it is associated with multiple adverse perinatal outcomes and future risk of developing type 2 diabetes mellitus (DM) and other cardiovascular diseases in affected mothers and children. In the United Arab Emirates (UAE), up to 1 in 4 pregnancies are affected by GDM. This PhD dissertation explores GDM screening, diagnosis, guideline use, and knowledge to provide a basis for primordial, primary, secondary, and tertiary levels of prevention in GDM care in the UAE. Three studies were conducted to achieve the PhD …

Positive Effects Of Covid-19 On Food Preparation And Expenditure Habits: A Comparative Study Across Three Countries, Asli Emine Özen, Asker Kartarl, Antonia Correia, Jun Wen, Metin Kozak

Research outputs 2022 to 2026

Objective:

This study seeks to empirically investigate how the changing eating habits affect health habits within three countries with entirely different cultures and diets to understand to what extent the pandemic may be responsible for these changes.

Design:

Specifically, a questionnaire was conducted in China, Portugal, and Turkey in early 2021. A series of statistical analyses were performed to identify how changes in individuals' eating habits have influenced their diets, considering the pandemic context and the varying cultural contexts where this research was performed.

Setting:

A structured questionnaire form was developed and uploaded to an online platform with unique links …

Anti-Müllerian Hormone Concentration Is Associated With Central Adiposity And Reproductive Hormones In Expectant Fathers, Narelle C. Hadlow, Suzanne J. Brown, Ee Mun Lim, David Prentice, Simone Pettigrew, Sophie L. Cronin, Susan L. Prescott, Desiree Silva, Bu B. Yeap

Research outputs 2022 to 2026

Objective:

The role of the anti-Müllerian hormone (AMH) as an indicator of physical and reproductive health in men is unclear. We assessed the relationships between AMH and follicle-stimulating hormone (FSH), luteinizing hormone (LH), testosterone, and metabolic parameters, in a cohort of expectant fathers.

Design:

ORIGINS Project prospective cohort study. Setting: Community-dwelling men.

Participants:

Partners of pregnant women attending antenatal appointments.

Main Outcome Measures:

Serum AMH, FSH, LH, testosterone, and metabolic parameters. Results: In 485 expectant fathers, median age 33 years, median AMH was 40 pmol/L (quartiles 29, 56). AMH was inversely correlated with FSH, age, and body mass index (BMI) …

The Effects Of Acute High-Intensity Interval Exercise And Hyperinsulinemic-Euglycemic Clamp On Osteoglycin Levels In Young And Middle-Aged Men, Carlie Bauer, Alexander Tacey, Andrew Garnham, Cassandra Smith, Mary N. Woessner, Xuzhu Lin, Navabeh Zarekookandeh, David L. Hare, Joshua R. Lewis, Lewan Parker, Itamar Levinger

Research outputs 2022 to 2026

Osteoglycin (OGN) is a leucine-rich proteoglycan that has been implicated in the regulation of glucose in animal models. However, its relationship with glucose control in humans is unclear. We examined the effect of high-intensity interval exercise (HIIE) and hyperinsulinemic-euglycemic clamp on circulating levels of OGN as well as whether circulating OGN levels are associated with markers of glycemic control and cardio-metabolic health. Serum was analyzed for OGN (ELISA) levels from 9 middle-aged obese men (58.1 ± 2.2 years, body mass index [BMI] = 33.1 ± 1.4 kg∙m ^{− 2}, mean ± SEM) and 9 young men (27.8 ± 1.6 …

Nurturing Children’S Development Through Healthy Eating And Active Living: Time For Policies To Support Effective Interventions In The Context Of Responsive Emotional Support And Early Learning, Helen Skouteris, Rachael Green, Alexandra Chung, Heidi Bergmeier, Lisa H Amir, Sukhpreet Kaur Baidwan, Angel Marie Chater, Catherine Chamberlain, Ruth Emond, Kay Gibbons, Michelle Gooey, Kostas Hatzikiriakidis, Emma Haycraft, Andrew P Hills, Daryl J Higgins, Oliver Hooper, Sue-Anne Hunter, Pam Kappelides, Sue Kleve, Jacynta Krakouer, Julie C Lumeng, Yannis Manios, Athar Mansoor, Michael Marmot, Louise C Mâsse, Karen Matvienko-Sikar, Zandile June-Rose Mchiza, Caroline Meyer, George Moschonis, Emily R Munro, Teresia Margareta O'Connor, Adrienne O'Neil, Thomas Quarmby, Rachel Sandford, Janet U Schneiderman, Simone Sherriff, Doug Simkiss, Alison Spence, Elizabeth Sturgiss, Dave Vicary, Rebecca Wickes, Luke Wolfenden, Mary Story, Maureen M Black

Faculty, Staff and Students Publications

Fostering the growth, development, health, and wellbeing of children is a global priority. The early childhood period presents a critical window to influence lifelong trajectories, however urgent multisectoral action is needed to ensure that families are adequately supported to nurture their children's growth and development. With a shared vision to give every child the best start in life, thus helping them reach their full developmental potential, we have formed the International Healthy Eating Active Living Matters (HEALing Matters) Alliance. Together, we form a global network of academics and practitioners working across child health and development, and who are dedicated to …

Rare Variants In Genes Encoding Subunits Of The Epithelial Na+ Channel Are Associated With Blood Pressure And Kidney Function, Brandon M Blobner, Annet Kirabo, Ossama B Kashlan, Shaohu Sheng, Donna K Arnett, Lewis C Becker, Eric Boerwinkle, Jenna C Carlson, Yan Gao, Richard A Gibbs, Jiang He, Marguerite R Irvin, Sharon L R Kardia, Tanika N Kelly, Charles Kooperberg, Stephen T Mcgarvey, Vipin K Menon, May E Montasser, Take Naseri, Susan Redline, Alexander P Reiner, Muagututi'a S Reupena, Jennifer A Smith, Xiao Sun, Dhananjay Vaidya, Karine A Viaud-Martinez, Daniel E Weeks, Lisa R Yanek, Xiaofeng Zhu, Ryan L Minster, Thomas R Kleyman

Faculty, Staff and Students Publications

Background: The epithelial Na+ channel (ENaC) is intrinsically linked to fluid volume homeostasis and blood pressure. Specific rare mutations in SCNN1A, SCNN1B, and SCNN1G, genes encoding the α, β, and γ subunits of ENaC, respectively, are associated with extreme blood pressure phenotypes. No associations between blood pressure and SCNN1D, which encodes the δ subunit of ENaC, have been reported. A small number of sequence variants in ENaC subunits have been reported to affect functional transport in vitro or blood pressure. The effects of the vast majority of rare and low-frequency ENaC variants on blood pressure are …

Running As A Way Fat Women Re-Story Their Bodies And Construct A Runner Identity In A North American Sociocultural Context, Jennifer M. Ohlendorf, Lisa Anders

College of Nursing Faculty Research and Publications

Aim

This research sought to identify the process by which women who identify as fat or as not having a typical athletic body construct an athletic identity and persist in their running and other athletic endeavors despite body size-related barriers.

Methods

From an online recruitment effort, 19 North American women runners in larger bodies completed interviews in which they told the story of how they had become runners. A narrative analysis with a feminist, constructivist approach was conducted to identify story types.

Results

Four narrative types were identified: reclaiming the body, reclaiming health, space-making, and future-imagining. Through finding a size- …

Global Changes In Chromatin Accessibility And Transcription In Growth Hormone-Secreting Pituitary Adenoma, Meng Wang, Chenxing Ji, Yichao Zhang, Zhiqiang Zhang, Yu Zhang, Huiping Guo, Nidan Qiao, Xiang Zhou, Xiaoyun Cao, Zhen Ye, Yifei Yu, Vladimir Melnikov, Wei Gong, Min He, Zhaoyun Zhang, Yao Zhao, Xuelong Wang, Gang Wei, Zhao Ye

Faculty, Staff and Student Publications

PURPOSE: Growth hormone-secreting pituitary adenoma (GHPA) is an insidious disease with persistent hypersecretion of growth hormone and insulin-like growth factor 1, causing increased morbidity and mortality. Previous studies have investigated the transcription of GHPA. However, the gene regulatory landscape has not been fully characterized. The objective of our study was to unravel the changes in chromatin accessibility and transcription in GHPA.

METHODS: Six patients diagnosed with GHPA in the Department of Neurosurgery at Huashan Hospital were enrolled in our study. Primary pituitary adenoma tissues and adjacent normal pituitary specimens with no morphologic abnormalities from these six patients were obtained at …

Opportunities And Challenges In Heart Rhythm Research: Rationale And Development Of An Electrophysiology Collaboratory, Duy T Nguyen, Kenneth C Bilchick, Sanjiv M Narayan, Mina K Chung, Kevin L Thomas, Kenneth R Laurita, Marmar Vaseghi, Roopinder Sandhu, Mihail G Chelu, Prince J Kannankeril, Douglas L Packer, David D Mcmanus, Atul Verma, Matthew Singleton, Khaldoun Tarakji, Sana M Al-Khatib, Jonathan R Kaltman, Ravi C Balijepalli, George F Van Hare, Jodie L Hurwitz, Andrea M Russo, Fred M Kusumoto, Christine M Albert

Faculty, Staff and Students Publications

There are many challenges in the current landscape of electrophysiology (EP) clinical and translational research, including increasing costs and complexity, competing demands, regulatory requirements, and challenges with study implementation. This review seeks to broadly discuss the state of EP research, including challenges and opportunities. Included here are results from a Heart Rhythm Society (HRS) Research Committee member survey detailing HRS members' perspectives regarding both barriers to clinical and translational research and opportunities to address these challenges. We also provide stakeholder perspectives on barriers and opportunities for future EP research, including input from representatives of the U.S. Food and Drug Administration, …

Optimal Cardiometabolic Health And Risk Of Heart Failure In Type 2 Diabetes: An Analysis From The Look Ahead Trial, Kershaw V Patel, Muhammad Shahzeb Khan, Matthew W Segar, Judy L Bahnson, Katelyn R Garcia, Jeanne M Clark, Ashok Balasubramanyam, Alain G Bertoni, Muthiah Vaduganathan, Michael E Farkouh, James L Januzzi, Subodh Verma, Mark Espeland, Ambarish Pandey

Faculty, Staff and Students Publications

Aims: To evaluate the contribution of baseline and longitudinal changes in cardiometabolic health (CMH) towards heart failure (HF) risk among adults with type 2 diabetes (T2D).

Methods and results: Participants of the Look AHEAD trial with T2D and without prevalent HF were included. Adjusted Cox models were used to create a CMH score incorporating target levels of parameters weighted based on relative risk for HF. The associations of baseline and changes in the CMH score with risk of overall HF, HF with preserved (HFpEF) and reduced ejection fraction (HFrEF) were assessed using Cox models. Among the 5080 participants, 257 incident …

Evolution Of Immune Function In Response To Dietary Macronutrients In Male And Female Decorated Crickets, Corinne Letendre, Alejandro Rios-Villamil, Alexandria Williams, James Rapkin, Scott K. Sakaluk, Clarissa M. House, John Hunt

Faculty Publications – Biological Sciences

Although dietary macronutrients are known to regulate insect immunity, few studies have examined their evolutionary effects. Here, we evaluate this relationship in the cricket Gryllodes sigillatus by maintaining replicate populations on four diets differing in protein (P) to carbohydrate (C) ratio (P‐ or C‐biased) and nutritional content (low‐ or high‐nutrition) for >37 generations. We split each population into two; one maintained on their evolution diet and the other switched to their ancestral diet. We also maintained populations exclusively on the ancestral diet (baseline). After three generations, we measured three immune parameters in males and females from each population. Immunity was …

Is Antibiotic Prophylaxis Necessary After Endoscopic Ultrasound-Guided Fine-Needle Aspiration Of Pancreatic Cysts?, Seifeldin Hakim, Mihajlo Gjeorgjievski, Zubair Khan, Michael E Cannon, Kevin Yu, Prithvi Patil, Roy Tomas Davee, Sushovan Guha, Ricardo Badillo, Laith Jamil, Nirav Thosani, Srinivas Ramireddy

Faculty, Staff and Student Publications

BACKGROUND/AIMS: Current society guidelines recommend antibiotic prophylaxis for 3 to 5 days after endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) of pancreatic cystic lesions (PCLs). The overall quality of the evidence supporting this recommendation is low. In this study, we aimed to assess cyst infection and adverse event rates after EUS-FNA of PCLs among patients treated with or without postprocedural prophylactic antibiotics.

METHODS: We retrospectively reviewed all patients who underwent EUS-FNA of PCLs between 2015 and 2019 at two large-volume academic medical centers with different practice patterns of postprocedural antibiotic prophylaxis. Data on patient demographics, cyst characteristics, fine-needle aspiration technique, periprocedural and …

Is Antibiotic Prophylaxis Necessary After Endoscopic Ultrasound-Guided Fine-Needle Aspiration Of Pancreatic Cysts?, Seifeldin Hakim, Mihajlo Gjeorgjievski, Zubair Khan, Michael E Cannon, Kevin Yu, Prithvi Patil, Roy Tomas Davee, Sushovan Guha, Ricardo Badillo, Laith Jamil, Nirav Thosani, Srinivas Ramireddy

Faculty, Staff and Student Publications

Background/aims: Current society guidelines recommend antibiotic prophylaxis for 3 to 5 days after endoscopic ultrasound-guided fine-needle aspiration (EUS-FNA) of pancreatic cystic lesions (PCLs). The overall quality of the evidence supporting this recommendation is low. In this study, we aimed to assess cyst infection and adverse event rates after EUS-FNA of PCLs among patients treated with or without postprocedural prophylactic antibiotics.

Methods: We retrospectively reviewed all patients who underwent EUS-FNA of PCLs between 2015 and 2019 at two large-volume academic medical centers with different practice patterns of postprocedural antibiotic prophylaxis. Data on patient demographics, cyst characteristics, fine-needle aspiration technique, periprocedural and …

The Association Of Human Leukocyte Antigen Genotyping Among Sudanese Patients With Rheumatoid Arthritis: Reference To Ethnicity, Deborah R Young, Benjamin D Hong, Kristina H Lewis, Silvia R Paz, Bhumi B Bhakta, Mayra Macias, Cecelia L Crawford, Adam Drewnowski, Ming Ji, Darren D Moore, Ernest Shen, Sameer B Murali, Karen J Coleman

Faculty, Staff and Student Publications

OBJECTIVE: This study examined the association of weight loss following bariatric surgery with self-reported sleep quality after accounting for other sleep-related factors.

METHODS: Participants were from the Bariatric Experience Long Term (BELONG) study. Participants completed a survey up to 6 months before surgery and approximately 1 year after surgery. The Pittsburgh Sleep Quality Index (PSQI) was used to measure sleep quality. One-year percentage total weight loss (%TWL) was determined from electronic medical records. Covariates included demographics, Charlson Comorbidity Index, geocoded variables to assess neighborhood quality, and physical activity. The authors assessed the association between %TWL at 1 year and PSQI …

Brain Structure In Acutely Underweight And Partially Weight-Restored Individuals With Anorexia Nervosa: A Coordinated Analysis By The Enigma Eating Disorders Working Group, Esther Walton, Fabio Bernardoni, Victoria-Luise Batury, Klaas Bahnsen, Sara Larivière, Giovanni Abbate-Daga, Susana Andres-Perpiña, Lasse Bang, Amanda Bischoff-Grethe, Samantha J Brooks, Iain C Campbell, Giammarco Cascino, Josefina Castro-Fornieles, Enrico Collantoni, Federico D'Agata, Brigitte Dahmen, Unna N Danner, Angela Favaro, Jamie D Feusner, Guido K W Frank, Hans-Christoph Friederich, John L Graner, Beate Herpertz-Dahlmann, Andreas Hess, Stefanie Horndasch, Allan S Kaplan, Lisa-Katrin Kaufmann, Walter H Kaye, Sahib S Khalsa, Kevin S Labar, Luca Lavagnino, Luisa Lazaro, Renzo Manara, Amy E Miles, Gabriella F Milos, Alessio Maria Monteleone, Palmiero Monteleone, Benson Mwangi, Owen O'Daly, Jose Pariente, Julie Roesch, Ulrike H Schmidt, Jochen Seitz, Megan E Shott, Joe J Simon, Paul A M Smeets, Christian K Tamnes, Elena Tenconi, Sophia I Thomopoulos, Annemarie A Van Elburg, Aristotle N Voineskos, Georg G Von Polier, Christina E Wierenga, Nancy L Zucker, Neda Jahanshad, Joseph A King, Paul M Thompson, Laura A Berner, Stefan Ehrlich

Faculty, Staff and Student Publications

Background: The pattern of structural brain abnormalities in anorexia nervosa (AN) is still not well understood. While several studies report substantial deficits in gray matter volume and cortical thickness in acutely underweight patients, others find no differences, or even increases in patients compared with healthy control subjects. Recent weight regain before scanning may explain some of this heterogeneity. To clarify the extent, magnitude, and dependencies of gray matter changes in AN, we conducted a prospective, coordinated meta-analysis of multicenter neuroimaging data.

Methods: We analyzed T1-weighted structural magnetic resonance imaging scans assessed with standardized methods from 685 female patients with AN …

A Subpopulation Of Oxytocin Neurons Initiate Expression Of Crf Receptor 1 (Crfr1) In Females Post Parturition, Lierni Ugartemendia, Rose M De Guzman, Jing Cai, Shivakumar Rajamanickam, Zhiying Jiang, Jonathan Tao, Damian G Zuloaga, Nicholas J Justice

Faculty, Staff and Student Publications

Oxytocin (OT) is essential for successful reproduction, particularly during parturition and lactation. During the postpartum period, OT also influences maternal behavior to promote bonding between mothers and their newborns, and increases stress resilience. However, the mechanism by which stress influences OT neuron activity and OT release has remained unclear. Here, we provide evidence that a subpopulation of OT neurons initiate expression of the receptor for the stress neuropeptide Corticotropin Releasing Factor (CRF), CRFR1, in reproductive females. OT neuron expression of CRFR1 begins at the first parturition and increases during the postpartum period until weaning. The percentage of OT neurons that …

Manufacturing-Dependent Change In Biological Activity Of The Tlr4 Agonist Gsk1795091 And Implications For Lipid A Analog Development, Neeltje Steeghs, Haeseong Park, Et Al.

2020-Current year OA Pubs

A phase I trial (NCT03447314; 204686) evaluated the safety and efficacy of GSK1795091, a Toll-like receptor 4 (TLR4) agonist, in combination with immunotherapy (GSK3174998 [anti-OX40 monoclonal antibody], GSK3359609 [anti-ICOS monoclonal antibody], or pembrolizumab) in patients with solid tumors. The primary endpoint was safety; other endpoints included efficacy, pharmacokinetics, and pharmacodynamics (PD). Manufacturing of GSK1795091 formulation was modified during the trial to streamline production and administration, resulting in reduced PD (cytokine) activity. Fifty-four patients received GSK1795091 with a combination partner; 32 received only the modified GSK1795091 formulation, 15 received only the original formulation, and seven switched mid-study from the original to …

Bilateral Optic Disc Drusen With Neuroretinitis, Jessica Kreinbrink Od, Andrew Weibel Od, Katherine Weibel Od

Optometric Clinical Practice

Background: Neuroretinitis is an inflammation of the posterior pole of the eye, resulting in optic disc edema and macular star formation. Systemic conditions associated with these findings include tuberculosis, toxoplasmosis, syphilis, lyme disease, toxocariasis, mumps, herpes simplex, and cat scratch disease. This case illustrates diagnosis and treatment for a patient with neuroretinitis complicated by preexisting vision loss.

Case Report: A Caucasian male in his 40’s presented to the eye clinic for an emergency appointment with complaints of constant blurry vision, especially inferiorly upon awakening, in his right eye for the past two weeks. His ocular history included optic disc …

Medicinal Plants’ Stress Factors: Effects On Metabolites And Novel Perspectives For Tolerance, Mayssaloune Ali Kanso, Mohamad Ali Hijazi, Maha Aboul Ela Prof., Abdalla El-Lakany

BAU Journal - Health and Wellbeing

Medicinal plants are rich in secondary metabolites representing different chemical classes and synthesized by various biochemical pathways. However, these compounds are susceptible to potential herbal predators and to environmental influences. Several factors induce different biotic and abiotic stresses (drought, cold, salinity, heat) that lead to fluctuations in the biogenesis and accumulation of secondary metabolites by which plants react to overcome the threatening stress conditions. This contribution aims to give an overview of the various medicinal plant defense mechanisms against imminent threats and their impact on secondary metabolites profiles in the most effective medicinal plant species such as the levels of …

Succenturiate Placental Lobe Abruption: A Placental Pathology Complicating A Dangerous Delivery, Morgan Stickler, Sydney M. Graham, Richard Conway, Adam M. Franks

Marshall Journal of Medicine

The development of a placenta is a complex process that occurs without a clinically significant issue in most pregnancies. At times, however, the process develops in a way that isolates an island of placental tissue away from the main body, connected only by unprotected vasculature within the amniotic membranes. The vessels of this succenturiate lobe of the placenta are vulnerable both to compression or laceration, threatening the antepartum period with poor weight gain or the peripartum period with fetal distress, hemorrhage or retained products of conception. A majority of the time, this pathology is undiagnosed until recognized innocuously following delivery …

The Dental Health Of Rural Elderly People And Its Social Justice Implications, Jacqueline Fox

West Virginia Law Review

No abstract provided.

International Human Rights As A Vehicle For Achieving Rural Health, David H. Moore, Emily Lowder, Cami Schiel

West Virginia Law Review

No abstract provided.

Why Aren't Mountain State Folks Getting The Shot?: Health Literacy, Covid-19, And Vaccination Rates In West Virginia Counties, Elizabeth Van Nostrand, Taylor J. Robinson, Aimee J. Palumbo

West Virginia Law Review

No abstract provided.

Emprendimiento E Innovación En El Contexto De La Crisis Sanitaria, César Augusto Giraldo Duque, Cesar Alberto Wilches Martínez, Falón Dayana Zamudio Barón, Brayan Esmid Anacona Galindo, Disney Rocío Mancera Riveros, Juan Manuel Ballen Campos, La Rotta Wendy García, Nicole Iveth Alvarado Díaz, Karen Tatiana Arias Bermúdez, Eliana Sulayn Diaz Rojas, Yeimy Dayana Gutiérrez Ortiz, Lisett Tatiana Romero Ballesteros, Miller Yorssdany Martínez Montaño, Darwin Felipe Peñuela Cita

Ciencias Administrativas, Económicas y Contables

El proyecto investigativo sobre “emprendimiento e innovación en el contexto de la crisis sanitaria”, es el resultado de un esfuerzo conjunto entre los estudiantes de contaduría pública IIPA 2020 del cuarto semestre tarde y noche del CADI “pensamiento administrativo”, quienes debían realizar propuestas de reactivación económica para los pequeños productores de las fincas que se han visto afectados por la pandemia y no han podido comercializar los productos cosechados.

En el proyecto también se tiene en cuenta aquellos productos que no cumplen con los estándares de calidad para ser llevados a un mercado y terminan perdiéndose en las fincas sea …

Educational Policies Committee, Agenda, November 3, 2022, Utah State University

Educational Policies Committee

• Approval of Minutes - October 6, 2022
• Subcommittee Reports
• Curriculum Subcommittee (Chad Simon)
• Academic Standards Subcommittee (Renee Galliher)
• General Education Subcommittee (Matt Sanders)
• Other Business
• Adjourn

Sex-Specific Role Of Myostatin Signaling In Neonatal Muscle Growth, Denervation Atrophy, And Neuromuscular Contractures., Marianne E Emmert, Parul Aggarwal, Kritton Shay-Winkler, Se-Jin Lee, Qingnian Goh, Roger Cornwall

Faculty Research 2023

Neonatal brachial plexus injury (NBPI) causes disabling and incurable muscle contractures that result from impaired longitudinal growth of denervated muscles. This deficit in muscle growth is driven by increased proteasome-mediated protein degradation, suggesting a dysregulation of muscle proteostasis. The myostatin (MSTN) pathway, a prominent muscle-specific regulator of proteostasis, is a putative signaling mechanism by which neonatal denervation could impair longitudinal muscle growth, and thus a potential target to prevent NBPI-induced contractures. Through a mouse model of NBPI, our present study revealed that pharmacologic inhibition of MSTN signaling induces hypertrophy, restores longitudinal growth, and prevents contractures in denervated muscles of female …

Gutka Consumption And Dietary Partialities Explaining Anemia In Women Of A Coastal Slum Of Karachi, Pakistan: A Mixed-Method Study, Ameer Muhammad, Sarah Saleem, Daniyaal Ahmad, Eleze Tariq, Yasir Shafiq

Community Health Sciences

Background: Limited literature is available on the dietary pattern and its consequences on health of women living in coastal slums of Karachi, Pakistan.
Material and methods: The study employed a mixed-method approach where concurrent quantitative and qualitative assessments were carried out. An analytical cross-sectional survey was conducted to collect information on demographic, household, obstetrics characteristics, and dietary pattern of married women of reproductive age (MWRA). Blood samples were collected to identify the hemoglobin level to determine anemia. For the qualitative component, focus group discussions were carried out with women and in-depth interviews with shopkeepers to understand the availability of food …

The Minutes Of The Marshall University Graduate Council Meeting, October 21, 2022, Marshall University Graduate Council

Graduate Council Minutes

No abstract provided.