Digital Commons Network^™

Single-Cell Massively Parallel Reporter Assays, Siqi Zhao

Arts & Sciences Graduate Student Theses and Dissertations

Our understanding of gene regulation needs to be generalizable as well as specific. A generalizable understanding enables us to transfer our knowledge of one gene to another, and the specificity allows us to understand the precise regulation of gene expression through development. One framework that confers generalizability and specificity is the hierarchical and modular model of gene regulation. To test whether gene regulation is hierarchical and modular requires methods to systematically analyze how different factors collectively control gene expression. This thesis describes the development of two functional genomics methods at single-cell resolution. These methods systematically examined how cellular contexts, chromatin …

Quasiparticle And Excitonic Effects In Two-Dimensional Van Der Waals Materials, Linghan Zhu

Arts & Sciences Graduate Student Theses and Dissertations

Since their discovery, low dimensional van der Waals materials have attracted increasing research interests. They serve as ideal platforms to study novel physics in reduced-dimensional systems, and are critical in nowadays’ nanotechnology applications. Due to the reduced dielectric screening in low dimensions, strong excited state properties dictate their electronic, transport and optical properties, the study of which calls for a description of the many-particle interactions beyond the traditional density functional theory. This is where the many-body perturbation theory comes into play. In this thesis, I will present a comprehensive study of the quasiparticle and excitonic properties of a variety of …

Functionalized Plasmonic Nanostructures For Ultrasensitive Single Cell Analysis, Priya Rathi

Arts & Sciences Graduate Student Theses and Dissertations

Ultrasensitive detection and quantification of soluble, secreted and cell surface-bound proteins is critical for advancing our understanding of cellular systems, enabling effective drug development, novel therapies, and bio-diagnostics. However, exiting technologies are largely limited by their sensitivity, making the detection and quantification of low-abundant proteins extremely challenging. This forms a major barrier in various fields of biology and biomedical sciences. In this work, we introduce novel cellular analysis methodologies based on plasmon-enhanced fluorescence for analyzing cell structure and probing surface and secreted proteins from cells. In the first part, we introduce plasmon-enhanced expansion microscopy and demonstrate the effectiveness of employing …

Effects Of Surface Ligation On Charge Extraction From Wurtzite Cadmium Selenide Quantum Platelets And Quantum Belts, Hailey Meyer

Arts & Sciences Graduate Student Theses and Dissertations

This dissertation presents the synthesis of flat, colloidal wurtzite CdSe quantum platelets and quantum belts for ligand exchange to novel and existing organic and inorganic L-, X-, and Z- type ligands. Use of these ligands in conjunction with the semiconductor nanocrystals allows for examination of their ligand exchange abilities, photoluminescence quenching efficiencies, and charge transfer properties.First, zinc and cadmium dithiocarbamate compounds [M(S2CNR1R2)2] are used as ligands on wurtzite CdSe quantum belts. Complete ligand exchange is achieved when the belts are initially ligated with Cd(oleate)2, a Z-type ligand, prior to the exchange, as opposed to n-octylamine or ammonia, which are both …

Toward Enhancing The Synthesis Of Renewable Polymers: Feedstock Conversions And Functionalizable Copolymers, Tedd Casey Wiessner

Arts & Sciences Graduate Student Theses and Dissertations

This thesis describes research under the rubric of the Center for Sustainable Polymers that is aimed at two separate goals. The goal of the first project (Chapters 1 and 2) was to develop a deeper mechanistic understanding of a method for the synthesis of linear α-olefins, while the second aimed at synthesizing statistical copolymers that incorporate olefin-containing monomers through ring-opening transesterification polymerization and showing that these copolymers could be functionalized. In Chapter 1, published methods for the conversion of fatty acids to linear α-olefins are reviewed to provide context for the mechanistic work we accomplished (Chapter 2). In Chapter 2 …

Federated Learning And Applications In Cybersecurity, Ani Sreekumar

Cybersecurity Undergraduate Research Showcase

Machine learning is a subfield of artificial intelligence that focuses on making predictions about some outcome based on information from a dataset. In cybersecurity, machine learning is often used to improve intrusion detection systems and identify trends in data that could indicate an oncoming cyber attack. Data privacy is an extremely important aspect of cybersecurity, and there are many industries that have more demanding laws to ensure the security of user data. Due to these regulations, machine learning algorithms can not be widely utilized in these industries to improve outcomes and accuracy of predictions. However, federated learning is a recent …

Covid-19 Prediction Using Machine Learning, Parashuram Singaraveni

Masters Projects

All around the globe, humankind faces a disastrous situation that witnessed COVID-19 outbreak. The COVID-19 pandemic caused severe loss of human life across the world. Most of the countries had been socially and economically weakened. The health sector faced lots of challenges in diagnosing the COVID patients, vaccinating the people, identifying the people who are infected by the virus. At the earlier stage, it has been difficult to identify the symptoms in infected person that is caused by the virus. Months later, symptoms were identified and, disease detecting machines were invented. But still, time taking for the results from the …

Curriculum Development In Technical Education For Boys And Girls Club, Damanpreet Singh

Masters Projects

Technical education has been and will continue to be more and more important to succeed in the future. The Boys and Girls Club, founded in 1860, is a national organization of local chapters which provide voluntary after-school programs for young individuals. The Boys and Girls Club have life-changing programs that prepare the young individuals in the club for their future whether it’s for college, career, or life. The perfect way to prepare best prepare these kids for the future is to develop their technical education. Unfortunately, the boys and girls club of Muskegon has a lack of educational resources for …

College Job Portal, Harikrishna Gonuguntla

Masters Projects

Through this project, I am producing a portal called "College Job Portal" that will make life easier for students, colleges, and the companies who hire the students by handling the hiring process. On-campus job placements are a crucial component in contemporary educational institutions. By entering information about their educational history, grades, technological abilities, and CV, students would register with the portal. Like students, companies would sign up with the site by supplying basic details like their address and contact information for human resources. The college would be the portal's administrator. Companies can advertise job openings using this site by including …

Malware Detection And Analysis, Namratha Suraneni

Masters Projects

Malicious software poses a serious threat to the cybersecurity of network infrastructures and is a global pandemic in the form of computer viruses, Trojan horses, and Internet worms. Studies imply that the effects of malware are deteriorating. The main defense against malware is malware detectors. The methods that such a detector employ define its level of quality. Therefore, it is crucial that we research malware detection methods and comprehend their advantages and disadvantages. Attackers are creating malware that is polymorphic and metamorphic and has the capacity to modify their source code as they spread. Furthermore, existing defenses, which often utilize …

Full-Text Search Using Elasticsearch, Akash Shrestha

Masters Projects

Search engines have changed the way we use the internet. They can search or filter out relevant and valuable content of interest to the users. But many of the applications we use today lack search or are just poor. So how can we leverage the same power of search engines in our applications? This project aims to look at “Full-Text Search” which allows us to do a text-based search in text-intensive data. The search will be performed by matching any, or all words of the query exactly or with some relevancy against the indexes created by the searching tool. The …

Docker Container Image – Vulnerability Scanning, Joseph U. Ohaeche

Masters Projects

The technology landscape for container adoption has greatly evolved over the years from the first known Unix U7 container concept introduced in 1979 to the most utilized docker container concept which emerged in 2013. Docker container image is essentially a lightweight, standalone executable software package with capabilities to run an application. It is important to know that container images become containers when deployed, and simultaneously docker container images become docker containers when deployed on Docker Engine. This project paper aims, evaluates, and presents a methodology useful in vulnerability scanning of docker container images and suggests possible fixes based on OWASP …

Diagnosis Of Neurodegenerative Diseases Using Higher Order Statistical Analysis Of Electroencephalography Signals, Seyed Alireza Khoshnevis

USF Tampa Graduate Theses and Dissertations

The field of signal processing has many applications, one of which is in the field of biomedical engineering where it has improved the performance of biomedical devices and the accuracy of medical diagnosis. One of the areas that have benefited from this field is the diagnosis of Parkinson’s disease (PD). This disease is one of the most common neurodegenerative diseases of the central nervous system. Nearly one million Americans suffer from PD, and this number goes up to over ten million people worldwide. The main symptoms of PD include bradykinesia, rest tremor, rigidity, and impaired balance. There are many types …

From Mapping Place To Mapping Space In Library Gis Work, Lena Denis

Journal of Critical Digital Librarianship

At many academic libraries, library workers run the teaching, general reference consultations, technical troubleshooting, and software and licensing maintenance in Geographic Information Systems (GIS) for their institutions. This is very much the case in the Data Services unit of Johns Hopkins University’s Sheridan Libraries, where staff receive requests for help with a wide variety of mapping projects every semester. Sometimes they are straightforward requests for technical assistance, but sometimes they underpin much deeper investigations into how to situate people and significant events through time and geographic settings. This article discusses these types of requests in the context of the philosophical …

Fall Commencement Program, December 14, 2022, Coastal Carolina University

Commencement Programs

Program of Commencement Exercises at Coastal Carolina University.

Community Colleges: An American Success Story, Glenn Dubois

Inquiry: The Journal of the Virginia Community Colleges

No abstract provided.

Remarks At The Vccs Chancellor's Annual Planning Retreat (2013), Glenn Dubois

Inquiry: The Journal of the Virginia Community Colleges

No abstract provided.

Remarks At The Senate Finance Subcommittee On Education (2012), Glenn Dubois

Inquiry: The Journal of the Virginia Community Colleges

No abstract provided.

Remarks At The Vccs Chancellor's Annual Planning Retreat (2012), Glenn Dubois

Inquiry: The Journal of the Virginia Community Colleges

No abstract provided.

A College Graduate In Every Virginia Home, Glenn Dubois

Inquiry: The Journal of the Virginia Community Colleges

No abstract provided.

A Usability Study Of Fido2 Hardware Tokens On Mobile Devices, Stephen Lambert

Theses and Dissertations

Passwords as the primary form of authentication on the web have many issues, such as password re-use across sites and difficulty in remembering secure passwords. The FIDO Alliance has created a passwordless system that has with support from companies like Google, Apple, and Microsoft: FIDO2. Studies have shown so far that users find FIDO2 usable on personal computers, but no work has been published on its usability on mobile devices. I conducted a lab study in which participants used FIDO2 passwordless authentication with hardware tokens on a mobile phone. Participants found FIDO2 usable on mobile devices, but had similar fears …

Computational Tools For Modeling And Simulation Of Sooting Turbulent Non-Premixed Flames, Victoria B. Stephens

Theses and Dissertations

Turbulent combustion systems are physically complex processes that involve many interdependent phenomena---including turbulent fluid dynamics, multi-component mass transfer, convective and radiative heat transfer, and multiphase flow---that occur over a wide range of length and time scales. Modeling and simulation studies complement experimental work by implementing and validating models and providing predictive capabilities, but current software tools are often limited by a lack of standardization and best practices, non-robust implementation, or over-specialization. Some topics in combustion CFD research, notably radiative heat transfer and soot modeling, are critically underrepresented in simulation studies as a result of software limitations. This project establishes and …

Assessing The Knowledge, Attitudes, And Practices Of Elementary Teacher Educators On The Inclusion Of Computational Thinking Through Coding, Megan Christine Swanson

Theses and Dissertations

This study sought to understand the knowledge, attitudes, and practices of teacher educators regarding Computational Thinking (CT) and coding. All elementary teacher educators in the state of Utah were sent a survey and asked to participate in a follow up interview. Twentynine faculty replied. Five of the 29 survey respondents were interviewed. Teacher educators shared their definitions of CT and coding, which primarily dealt with problem solving and computer programming, respectively. Overall attitudes were positive about incorporating CT and coding, but many participants questioned how it would fit into the already overwhelming nature of the elementary education major. However, those …

Cloud Container Security’ Next Move, Vishakha Sadhwani

Dissertations and Theses

In the last few years, it is apparent to cybersecurity experts everywhere that the proverbial container tech genie is out of the bottle, and has been widely embraced across multiple organizations. To achieve the flexibility of building and deploying applications anywhere and everywhere, cloud native environments have gained great momentum and made the development lifecycle simpler than ever. However, container environments brings with them a range of cybersecurity issues that includes images, containers, hosts, runtimes, registries, and orchestration platforms, which needs the necessity to focus on investing in securing your container stack.

According to this report[1], released by cloud-native …

The Effect Of Daily Fluency On Algebraic Procedural Fluency In Students, Osman Mohamoud

Dissertations, Theses, and Projects

Abstract

Algebra 1 students in the ninth grade struggled to follow procedural steps to answer elementary algebraic problems. An early pre-test found that the majority of pupils lacked the necessary fundamental knowledge to comprehend and investigate algebra's abstract concepts, patterns, and relationships. Fifteen students from one of the researcher's algebra one classes participated in a daily fluency skill-building intervention program to investigate whether daily fluency practice will affect students' procedural fluency skills. They engaged in 50 minutes of daily fluency practice for five weeks. During each 50-minute session, students practiced specific skills to develop procedural fluency competencies, such as solid …

Uv-Light-Tunable P-/N-Type Chemiresistive Gas Sensors Based On Quasi-1d Tis3 Nanoribbons: Detection Of Isopropanol At Ppm Concentrations, Victor V. Sysoev, Andrey V. Lashkov, Alexey Lipatov, Ilya A. Plugin, Michael Bruns, Dirk Fuchs, Alexey S. Varezhnikov, Mustahsin Adib, Martin Sommer, Alexander Sinitskii

Department of Chemistry: Faculty Publications

The growing demand of society for gas sensors for energy-efficient environmental sensing stimulates studies of new electronic materials. Here, we investigated quasi-one-dimensional titanium trisulfide (TiS₃) crystals for possible applications in chemiresistors and on-chip multisensor arrays. TiS₃ nanoribbons were placed as a mat over a multielectrode chip to form an array of chemiresistive gas sensors. These sensors were exposed to isopropanol as a model analyte, which was mixed with air at low concentrations of 1–100 ppm that are below the Occupational Safety and Health Administration (OSHA) permissible exposure limit. The tests were performed at room temperature (RT), as …

Predicted Episode Of Submarine Groundwater Discharge Onto The South Carolina, Usa, Continental Shelf And Its Effect On Dissolved Oxygen, Wilson S. Moore, Jacob Vincent, James L. Pickney, Alicia M. Wilson

Faculty Publications

Submarine groundwater discharge (SGD) may directly influence the dissolved oxygen (DO) content of coastal bottom waters. Here, we report a predicted episode of enhanced SGD that caused low DO concentrations on the South Carolina continental shelf. The prediction model linked episodes of SGD to upwelling-favorable winds. The data revealed these waters were a factor of 2–6 higher in ²²⁶Ra and ²²⁸Ra compared to typical bottom water values and were significantly depleted in DO (<130 μM). The tight ²²⁸Ra:²²⁶Ra correlation of these data was similar to values during a strong hypoxic event off SC in 2012. Water ages from …

Newsroom, Georgia Southern University

Newsroom (2006-2023)

• Approximately 2,100 Degrees Conferred During Georgia Southern’s 2022 Fall Commencement Ceremonies
• Graduating Student had ‘Wild’ Time at Georgia Southern
• Educator Turned Soldier: Georgia Southern ROTC Graduate Commissions as Officer in National Guard After Returning for MBA Degree
• Nontraditional Student Returns to Georgia Southern University to Chart New Career Path

Observation Of The Ξ_B^-→Λ_B^0 Π^- Decay And Measurement Of B(Ξ_B^-→Λ_B^0 Π^-), Zhuoming Li

Dissertations - ALL

We present the first observation of the weak decay Ξ−b → Λ0b π−, which is mediated by an s → u ̄ud transitionwithin the Ξ_b^- baryon. The analysis uses a pp collision data sample at a center-of-mass energy of 13 TeV corresponding to 5.5 fb^(−1) of integrated luminosity. The sample of Λb0 baryons used in this analysis are reconstructed through their decays to Λ+c π− and Λ+c π−π+π−. From a fit to the Ξ−b → Λ0b π− mass spectrum, the Ξ−b → Λ0b π− decay is observed with a significance of 11.3 standard deviations, thus establishing observation of this decay. …

Does Science Need Intersubjectivity? The Problem Of Confirmation In Orthodox Interpretations Of Quantum Mechanics, Emily Adlam

Mathematics, Physics, and Computer Science Faculty Articles and Research

Any successful interpretation of quantum mechanics must explain how our empirical evidence allows us to come to know about quantum mechanics. In this article, we argue that this vital criterion is not met by the class of ‘orthodox interpretations,’ which includes QBism, neo-Copenhagen interpretations, and some versions of relational quantum mechanics. We demonstrate that intersubjectivity fails in radical ways in these approaches, and we explain why intersubjectivity matters for empirical confirmation. We take a detailed look at the way in which belief-updating might work in the kind of universe postulated by an orthodox interpretation, and argue that observers in such …