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2022

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Optimizing Exposure For Contamination Ocd: What Happens When Digust Is Specifically Targeted?, Molly E. Wickenhauser Aug 2022

Optimizing Exposure For Contamination Ocd: What Happens When Digust Is Specifically Targeted?, Molly E. Wickenhauser

Electronic Theses and Dissertations

Disgust is a basic emotion with distinct subjective, physiological, cognitive, and behavioral processes that include revulsion, parasympathetic nervous system activity, contamination-specific appraisals, and disease-avoidance behaviors. Pathological disgust responses may contribute to the development and maintenance of anxiety-related psychopathology, particularly spider and blood-injection-injury phobias, health anxiety, post-traumatic stress disorder, and obsessive-compulsive disorder (OCD). Evidence-based treatments for these disorders were developed based on theories of fear and anxiety and involve exposure-based cognitive-behavior therapy. However, traditional exposure methods appear to be less effective at achieving habituation to disgust compared to fear and anxiety. Additionally, individuals with elevated disgust and primary contagion concerns seem …


Going Viral: A Qualitative Analysis Of The Anti-Vaccine Movement & Social Media, Corinn Evancho Schumacher Aug 2022

Going Viral: A Qualitative Analysis Of The Anti-Vaccine Movement & Social Media, Corinn Evancho Schumacher

Boise State University Theses and Dissertations

In the recent years of the rise of Web 2.0, health information has become more accessible. With this shift has come a reliance on social media to inform and educate the masses on vaccines. With the introduction of the Covid-19 vaccine, the conversation surrounding vaccines moved to the forefront of the United States’ zeitgeist from late 2021 to early 2022. In this research, I conducted a case study on the communication surrounding vaccines on social media while examining specific Facebook groups that advance the misinformation surrounding vaccines. I examined over 300 posts from four public Facebook groups in order to …


Examining Mental Health Disparities In A Rural County: A Community Health Needs Assessment Analysis, Dustin M. Schulz Aug 2022

Examining Mental Health Disparities In A Rural County: A Community Health Needs Assessment Analysis, Dustin M. Schulz

Capstone Experience: Master of Public Health

Over 20% of adults in the United States experience some form of mental illness each year. Those residing in rural areas can see increased prevalence of mental illness, and typically face disparities in access and availability of services for mental health. The goal of this project was to examine the impact of mental health in Woodford County, Illinois using data collected through the 2022 Community Health Needs Assessment (CHNA) process, with the intent of identifying areas of improvement that could be implemented at the local level. Analysis of the CHNA data was conducted using frequency analysis in SAS 9.4 through …


An Analysis Of Demographics And Risk Factors Associated With Increasing Syphilis Cases In Iowa, Eleanore H. Nelson Aug 2022

An Analysis Of Demographics And Risk Factors Associated With Increasing Syphilis Cases In Iowa, Eleanore H. Nelson

Capstone Experience: Master of Public Health

Background:

Syphilis is easily detectable and treatable with the appropriate medical attention, yet national incidence rates have been on the rise since reaching an all-time low in 2000 (Shockman et al, 2014). Similar to HIV, men who have sex with other men (MSM), represent most syphilis transmission, yet in recent years, syphilis rates have concerningly increased among both genders and among all racial/ethnic groups (CDC, 2019).

Methods:

Surveillance data was collected on all syphilis cases reported to the Iowa Department of Public Health (IDPH) regarding demographics and risk factors of cases. Variables were analyzed using chi-square and Fisher’s exact tests, …


Retrospective Identification Of Infection In The Emergency Department: A Significant Challenge In Sepsis Clinical Trials, Catherine S. O'Neal, Diana Hamer, Mandi W. Musso, Terrell S. Caffery, Morgan K. Walker, Katherine W. Lavie, Matthew S. Berlinger, Christopher B. Thomas, Shannon M. Alwood, Tonya Jagneaux, Michael A. Sanchez, Hollis R. O'Neal Aug 2022

Retrospective Identification Of Infection In The Emergency Department: A Significant Challenge In Sepsis Clinical Trials, Catherine S. O'Neal, Diana Hamer, Mandi W. Musso, Terrell S. Caffery, Morgan K. Walker, Katherine W. Lavie, Matthew S. Berlinger, Christopher B. Thomas, Shannon M. Alwood, Tonya Jagneaux, Michael A. Sanchez, Hollis R. O'Neal

School of Medicine Faculty Publications

Background: This study examined three methods for retrospectively identifying infection in emergency department (ED) patients: modified objective definitions of infection (MODI) from the CDC/NHSN, physician adjudication determination of infection, and ED treating physician behavior. Methods: This study used a subset of data from a prospective sepsis trial. We used Fleiss's Kappa to compare agreement between two physicians retrospectively adjudicating infection based on the patient's medical record, modified infection definition from the CDC/NHSN, and ED treating physician behavior. Results: Overall, there was similar agreement between physician adjudication of infection and MODI criteria (Kappa=0.59) compared to having two physicians independently identify infection …


University Of Central Florida Graduate Catalog, 2022 - 2023, University Of Central Florida Aug 2022

University Of Central Florida Graduate Catalog, 2022 - 2023, University Of Central Florida

UCF Catalogs

No abstract provided.


Could Cultures Determine The Course Of Epidemics And Explain Waves Of Covid-19?, Md Salman Rahman Aug 2022

Could Cultures Determine The Course Of Epidemics And Explain Waves Of Covid-19?, Md Salman Rahman

Theses and Dissertations

Coronavirus Disease (COVID-19), caused by the SARS-CoV-2 virus, is an infectious disease that quickly became a pandemic spreading with different patterns in each country. Travel bans, lockdowns, social distancing, and non-essential business closures caused significant economic disruptions and stalled growth worldwide in the pandemic’s first year. In almost every country, public health officials forced and/or encouraged Nonpharmaceutical Interventions (NPIs) such as contact tracing, social distancing, masks, and quarantine. Human behavioral decision-making regarding social isolation significantly impedes global success in containing the pandemic. This thesis focuses on human behaviors and cultures related to the decision-making of social isolation during the pandemic. …


Household Transmission Of Group A Streptococcus Necrotizing Fasciitis., Michael Markowitz, Stephanie Kwan, Jonas Matzon Aug 2022

Household Transmission Of Group A Streptococcus Necrotizing Fasciitis., Michael Markowitz, Stephanie Kwan, Jonas Matzon

Department of Orthopaedic Surgery Faculty Papers

A healthy 40-year-old woman was diagnosed with necrotizing fasciitis 2 days after her husband's death from the same infectious process. Prompt identification and immediate surgical intervention prevented a similar result in this patient. Additional investigation into both patients' medical records found the inciting organism to be group A streptococcus. Although the exact mechanism of inoculation is unknown, the spread of this infection within a household prompts the question of whether antibiotic prophylaxis should be given among close contacts in future cases of necrotizing fasciitis.


The Influences Of Disperser Behavior, Host Availability, And Environmental Conditions On The Distribution Of Oak Mistletoe [Phoradendron Leucarpum (Raf.) Reveal & M. C. Johnst.] In Eastern Virginia And North Carolina, Nicholas Pearce Flanders Aug 2022

The Influences Of Disperser Behavior, Host Availability, And Environmental Conditions On The Distribution Of Oak Mistletoe [Phoradendron Leucarpum (Raf.) Reveal & M. C. Johnst.] In Eastern Virginia And North Carolina, Nicholas Pearce Flanders

Biological Sciences Theses & Dissertations

Mistletoes are shrubs that typically parasitize the branches of host trees and rely on avian frugivores for seed dispersal. Because mistletoes are restricted to a narrow range of suitable recruitment sites and avian frugivores are more visible than other guilds of seed dispersers, mistletoe-frugivore systems afford opportunities for assessing the roles of dispersal limitation and local environment in determining plant distribution. These mechanisms have been proposed as determinants of the observed association of oak mistletoe [Phoradendron leucarpum (Raf.) Reveal & M. C. Johnst.] with forested wetlands in eastern Virginia and North Carolina, USA. I tested the alternative hypothesis that …


Study The Effect Of Harmful Radiation On Patients, Eyes From 15-25 Years During Using Smart Devices, Mundher Sameen Shuker, Zina Tariq Ali Aug 2022

Study The Effect Of Harmful Radiation On Patients, Eyes From 15-25 Years During Using Smart Devices, Mundher Sameen Shuker, Zina Tariq Ali

Al-Nisour Journal for Medical Sciences

The aim of this study was to assess the unsafe effects of harmful radiation, especially blue light and ultraviolet rays on patients' eyes aged (15-25) years during us exposure. It was carried out at the optics consulting clinic of the College of Health and Medical Technology in Baghdad/Iraq. In this research, (50) patients were enrolled, 28 males and 22 females, with their ages ranging from (15- 25) years. The smart devices are used by all patients for 2 to 5 hours daily. The majority of the patients were middle school and university students, accounting for 94 % of the patient …


Client’S Satisfaction Regarding Immunization Program Services Of Children Under 5 Years In Al- Diwaniyah Governorate, Iraq, Fadel Mohammed Jasem, Ali Hussein Al-Hafidh Aug 2022

Client’S Satisfaction Regarding Immunization Program Services Of Children Under 5 Years In Al- Diwaniyah Governorate, Iraq, Fadel Mohammed Jasem, Ali Hussein Al-Hafidh

Al-Nisour Journal for Medical Sciences

Immunization against infectious diseases is one of the most successful public health interventions; it is safe and economically feasible. The aim of the vaccination process is to prevent disability and death resulting from diseases that can be prevented by vaccines. Smallpox was completely eradicated in the previous period using vaccination programs, and now the world is close to eradicating polio. To evaluate the client’s satisfaction with the services of the expanded program of immunization in Diwaniyah governorate / Iraq. Cross-sectional descriptive study and included a random sample of clients consisting of 420 caregivers (mothers, fathers, and relatives of children) were …


Steven Johnson Syndrome/Toxic Epidermal Necrolysis Management In The Pediatric Population: The Surgeon’S Perspective, Shai Stewart Md, James Fraser, Ladonna Kearse, Pablo Aguayo Aug 2022

Steven Johnson Syndrome/Toxic Epidermal Necrolysis Management In The Pediatric Population: The Surgeon’S Perspective, Shai Stewart Md, James Fraser, Ladonna Kearse, Pablo Aguayo

Presentations

Introduction

Stevens–Johnson Syndrome and Toxic Epidermal Necrolysis are rare, life-threatening cutaneous reactions resulting in epidermal detachment that is likened to partial thickness burns. There are sparse data with regards to wound management in the pediatric literature. We aimed to explore the current practices of pediatric-only burn centers in the Pediatric Injury Quality Improvement Collaborative to lay the framework for a standardized approach to wound care.

Methods

A 36-item survey was administered to pediatric surgeons at participating centers of the consortium. No patient specific data was collected.

Results

Surveys were completed from 4 out of the 5 institutions. The admitting service …


Examining The Effect Of Gratitude On Intolerance Of Uncertainty And Loneliness, Adam John Paul Mackenzie Aug 2022

Examining The Effect Of Gratitude On Intolerance Of Uncertainty And Loneliness, Adam John Paul Mackenzie

Dissertations

Loneliness has been demonstrated to have significant negative effects on overall well-being in the general population. Previous literature has demonstrated a significant association between loneliness and various demographic variables such as gender, age, educational attainment, relationship status, living arrangements and income. Because of the unique impact that the disease caused by the coronavirus, COVID–19, has had on a global scale in relation to physical distancing and increasing physical and psychological distress, the purpose of this study was to examine the role that gratitude played in the relationship between intolerance of uncertainty and loneliness among the general adult population of the …


New Antiretroviral Drugs In The Pandemic, Thana Khawcharoenporn Aug 2022

New Antiretroviral Drugs In The Pandemic, Thana Khawcharoenporn

Asian Medical Journal and Alternative Medicine

The pandemic of coronavirus disease-19 (COVID-19) has impacted the care of people living with human immunodeficiency virus (HIV) and HIV prevention in several ways. Locking down and limiting transportation to slow down COVID-19 transmission can cause difficulty accessing and non-compliance to daily-dosing antiretroviral drugs (ARVs). The new formu-lations of ARVs, including long-acting ones administered as injections and implants are being approved and developed for HIV treatment and prevention. Intramuscular cabotegravir and rilpivirine co-formulation is approved by the US Food and Drug Administration for HIV treatment in virologically suppressed adults on a stable regimen, while intramuscular cabotegravir is approved for HIV …


The Role Of Middle And High School Principals During The Covid-19 Pandemic: A Phenomenological Study, Dustin Ford Aug 2022

The Role Of Middle And High School Principals During The Covid-19 Pandemic: A Phenomenological Study, Dustin Ford

Electronic Theses and Dissertations

The purpose of this qualitative study was to examine middle and high school principal roles prior to and during the COVID-19 pandemic to gain a better understanding about how leadership responsibilities adapted or changed. Data collection strategies included one-on-one interviews with nine middle and high school principals in East Tennessee. To qualify for the study participants had to have experience in the principalship prior to the pandemic. The analysis of data was based on the theoretical frameworks of adaptive leadership (Heifetz et al., 2009) and change theory (Fullan, 2020). The results revealed five key themes that were consistent during the …


In Vivo Efficacy Of Pyrantel Pamoate As A Post-Exposure Prophylactic For Rat Lungworm (Angiostrongylus Cantonensis), John Jacob, Argon Steel, Lisa Kaluna, Steven Hess, Israel Leinbach, Carmen Antaky, Robert Sugihara, Lindsey Hamilton, Peter Follett, Kathleen Howe, Steven Jacquier, Supakit Wongwiwatthananukit, Susan Jarvi Aug 2022

In Vivo Efficacy Of Pyrantel Pamoate As A Post-Exposure Prophylactic For Rat Lungworm (Angiostrongylus Cantonensis), John Jacob, Argon Steel, Lisa Kaluna, Steven Hess, Israel Leinbach, Carmen Antaky, Robert Sugihara, Lindsey Hamilton, Peter Follett, Kathleen Howe, Steven Jacquier, Supakit Wongwiwatthananukit, Susan Jarvi

United States Department of Agriculture Wildlife Services: Staff Publications

Rat lungworm (Angiostrongylus cantonensis) is a neurotropic nematode, and the leading cause of eosinophilic meningitis worldwide. The parasite is usually contracted through ingestion of infected gastropods, often hidden in raw or partially cooked produce. Pharmaceutical grade pyrantel pamoate was evaluated as a post-exposure prophylactic against A. cantonensis. Pyrantel pamoate is readily available over-the-counter in most pharmacies in the USA and possesses anthelmintic activity exclusive to the gastrointestinal tract (GIT). Administering pyrantel pamoate immediately after exposure should theoretically paralyze the larvae in the GIT, causing the larvae to be expelled via peristalsis without entering the systemic circulation. In this study, pyrantel …


Current Ecotoxicity Testing Needs Among Selected U.S. Federal Agencies, Patricia Ceger, Natalia Garcia-Reyero Vinas, David Allen, Elyssa Arnold, Raanan Bloom, Jennifer C. Brennan, Carol Clarke, Karen Eisenreich, Kellie Fay, Jonathan Hamm, Paula F.P. Henry, Katherine E. Horak, Wesley Hunter, Donna Judkins, Patrice Klein, Nicole Kleinstreuer, Kara Koehrn, Carlie A. Lalone, James P. Laurenson, Jessica K. Leet, Anna Lowit, Scott G. Lynn, Teresa Norberg-King, Edward J. Perkins, Elijah J. Petersen, Barnett A. Rattner, Catherine S. Sprankle, Thomas Steeger, Jim E. Warren, Sarah Winfield, Edward Odenkirchen Aug 2022

Current Ecotoxicity Testing Needs Among Selected U.S. Federal Agencies, Patricia Ceger, Natalia Garcia-Reyero Vinas, David Allen, Elyssa Arnold, Raanan Bloom, Jennifer C. Brennan, Carol Clarke, Karen Eisenreich, Kellie Fay, Jonathan Hamm, Paula F.P. Henry, Katherine E. Horak, Wesley Hunter, Donna Judkins, Patrice Klein, Nicole Kleinstreuer, Kara Koehrn, Carlie A. Lalone, James P. Laurenson, Jessica K. Leet, Anna Lowit, Scott G. Lynn, Teresa Norberg-King, Edward J. Perkins, Elijah J. Petersen, Barnett A. Rattner, Catherine S. Sprankle, Thomas Steeger, Jim E. Warren, Sarah Winfield, Edward Odenkirchen

United States Department of Agriculture Wildlife Services: Staff Publications

U.S. regulatory and research agencies use ecotoxicity test data to assess the hazards associated with substances that may be released into the environment, including but not limited to industrial chemicals, pharmaceuticals, pesticides, food additives, and color additives. These data are used to conduct hazard assessments and evaluate potential risks to aquatic life (e.g., invertebrates, fish), birds, wildlife species, or the environment. To identify opportunities for regulatory uses of non-animal replacements for ecotoxicity tests, the needs and uses for data from tests utilizing animals must first be clarified. Accordingly, the objective of this review was to identify the ecotoxicity test data …


Defining An Epidemiological Landscape That Connects Movement Ecology To Pathogen Transmission And Pace-Of-Life, Kezia Manlove, Mark Wilber, Lauren White, Guillaume Bastille-Rousseau, Anni Yang, Marie L.J. Gilbertson, Meggan E. Craft, Paul C. Cross, George Wittemyer, Kim M. Pepin Aug 2022

Defining An Epidemiological Landscape That Connects Movement Ecology To Pathogen Transmission And Pace-Of-Life, Kezia Manlove, Mark Wilber, Lauren White, Guillaume Bastille-Rousseau, Anni Yang, Marie L.J. Gilbertson, Meggan E. Craft, Paul C. Cross, George Wittemyer, Kim M. Pepin

United States Department of Agriculture Wildlife Services: Staff Publications

Pathogen transmission depends on host density, mobility and contact. These components emerge from host and pathogen movements that themselves arise through interactions with the surrounding environment. The environment, the emergent host and pathogen movements, and the subsequent patterns of density, mobility and contact form an ‘epidemiological landscape’ connecting the environment to specific locations where transmissions occur. Conventionally, the epidemiological landscape has been described in terms of the geographical coordinates where hosts or pathogens are located. We advocate for an alternative approach that relates those locations to attributes of the local environment. Environmental descriptions can strengthen epidemiological forecasts by allowing for …


Relationships Between Covid-19 Infection Rates, Healthcare Access, Socioeconomic Status, And Cultural Diversity, Marghece P. J. Barnes Aug 2022

Relationships Between Covid-19 Infection Rates, Healthcare Access, Socioeconomic Status, And Cultural Diversity, Marghece P. J. Barnes

Boise State University Theses and Dissertations

The COVID-19 pandemic has had a disproportionate impact on racial and ethnic minority groups, with high infection rates throughout those communities. There are a complex set of factors that account for COVID-19 disparities. Focusing on infection and death rates alone without also examining health equity, underestimates the true impact of the pandemic. To gain a more clear understanding of COVID-19’s impact in these communities, we analyzed the relationship between state COVID-19 infection rates with social determinants of health: cultural diversity, health care access, and socioeconomic status. Our approach to identifying this relationship was to estimate infection rates by fitting John …


The Intersections Of Sex And Inequality In A Mixed Status Industrial London Sample, Anna Green Aug 2022

The Intersections Of Sex And Inequality In A Mixed Status Industrial London Sample, Anna Green

Boise State University Theses and Dissertations

Saint Pancras Burial Ground and its inhumated priests, paupers, aristocrats, and migrants provide a unique perspective into the interactions between sex and inequality in 18th and 19th century industrial London. Frequencies of caries, dental calculus, periodontal disease, linear enamel hypoplasia, periapical lesions, tuberculosis, treponematosis, rickets, and trauma among 224 females from St. Pancras were compared to 27 low-status females from Crossbones Burial Ground and 74 primarily high-status females from Chelsea Old Church Cemetery. Based on the information known about those buried at St. Pancras, it was hypothesized that the frequencies of health indicators in St. Pancras should fall between the …


A Systematic Review And Meta-Analysis On Prevalence Of And Risk Factors Associated With Depression, Anxiety And Insomnia In Infectious Diseases, Including Covid-19: A Call To Action, Kai Yuan, Yong-Bo Zheng, Yi-Jie Wang, Yan-Kun Sun, Yi-Miao Gong, Yue-Tong Huang, Xuan Chen, Xiao-Xing Liu, Yi Zhong, Si-Zhen Su, Nan Gao, Yi-Long Lu, Zhe Wang, Wei-Jian Liu, Jian-Yu Que, Ying-Bo Yang, An-Yi Zhang, Meng-Ni Jing, Chen-Wei Yuan, Na Zeng, Michael V Vitiello, Vikram Patel, Seena Fazel, Harry Minas, Graham Thornicroft, Teng-Teng Fan, Xiao Lin, Wei Yan, Le Shi, Jie Shi, Thomas Kosten, Yan-Ping Bao, Lin Lu Aug 2022

A Systematic Review And Meta-Analysis On Prevalence Of And Risk Factors Associated With Depression, Anxiety And Insomnia In Infectious Diseases, Including Covid-19: A Call To Action, Kai Yuan, Yong-Bo Zheng, Yi-Jie Wang, Yan-Kun Sun, Yi-Miao Gong, Yue-Tong Huang, Xuan Chen, Xiao-Xing Liu, Yi Zhong, Si-Zhen Su, Nan Gao, Yi-Long Lu, Zhe Wang, Wei-Jian Liu, Jian-Yu Que, Ying-Bo Yang, An-Yi Zhang, Meng-Ni Jing, Chen-Wei Yuan, Na Zeng, Michael V Vitiello, Vikram Patel, Seena Fazel, Harry Minas, Graham Thornicroft, Teng-Teng Fan, Xiao Lin, Wei Yan, Le Shi, Jie Shi, Thomas Kosten, Yan-Ping Bao, Lin Lu

Children’s Nutrition Research Center Staff Publications

Infectious disease epidemics have become more frequent and more complex during the 21st century, posing a health threat to the general public and leading to psychological symptoms. The current study was designed to investigate the prevalence of and risk factors associated with depression, anxiety and insomnia symptoms during epidemic outbreaks, including COVID-19. We systematically searched the PubMed, Embase, Web of Science, OVID, Medline, Cochrane databases, bioRxiv and medRxiv to identify studies that reported the prevalence of depression, anxiety or insomnia during infectious disease epidemics, up to August 14th, 2020. Prevalence of mental symptoms among different populations including the general public, …


Covid-19 Vaccines And Related Adverse Effects Among Health Sciences And Non-Health Sciences Students From Two Large Public Universities In Thailand, Thana Khawcharoenporn, Kanathip Jongmekwamsuk, Sirashat Hanvivattanakul, Jakaphat Vanichanan Aug 2022

Covid-19 Vaccines And Related Adverse Effects Among Health Sciences And Non-Health Sciences Students From Two Large Public Universities In Thailand, Thana Khawcharoenporn, Kanathip Jongmekwamsuk, Sirashat Hanvivattanakul, Jakaphat Vanichanan

Asian Medical Journal and Alternative Medicine

Introduction: Existing data on vaccine regimensreceived by university students and related adverse effects (AEs) are limited.

Objectives: To assess types and AEs of COVID-19 vaccines received by Thai university students.

Methods: An online survey study was conducted among students from 12 Health Sciences faculties (HS), and from 16 non-Health Sciences faculties (NHS) of two universities from October 2021 to January 2022.

Results: There were 1,439 participating students; 522 (36%) were HS and 917 (64%) were NHS. The types of the first-dose vaccine received were inactivated (49%), viral vector (VV; 46%), and mRNA (5%), while the types of the second-dose vaccine …


The Role Of The Hypoxia-Inducible Factor 2 In Pancreatic Cancer: Mechanisms Of Tumor Immunosuppression And Intestinal Radioprotection, Carolina Garcia Garcia Aug 2022

The Role Of The Hypoxia-Inducible Factor 2 In Pancreatic Cancer: Mechanisms Of Tumor Immunosuppression And Intestinal Radioprotection, Carolina Garcia Garcia

Dissertations and Theses (Open Access)

Pancreatic ductal adenocarcinoma (PDAC) is a devastating disease with dismal prognosis. The only curative option for patients is surgery, but over 80% of patients are not surgical candidates. Unfortunately, PDAC is resistant to the three remaining options. PDAC is characterized by a profoundly hypoxic and immunosuppressive stroma, which contributes to its therapeutic recalcitrance. Alpha-smooth muscle actin+ (αSMA+) cancer-associated fibroblasts (CAFs) are the most abundant stromal component, as well as mediators of stromal deposition. The hypoxia-inducible factors (HIF1 and HIF2) coordinate responses to hypoxia, yet, despite their known association to poor patient outcomes, their functions within the PDAC tumor microenvironment (TME) …


Heat Stress Response And Excystation In Entamoeba Histolytica, Irem Bastuzel Aug 2022

Heat Stress Response And Excystation In Entamoeba Histolytica, Irem Bastuzel

All Dissertations

Entamoeba histolytica is a water- and food-borne intestinal protozoan parasite that causes amoebiasis and liver abscess and is responsible for symptomatic disease in approximately 100 million people each year leading to ~ 100,000 deaths. The most common disease transmission follows the oral-fecal route, but it can also be transmitted by mechanical vectors such as animals carrying the amoeba from contaminated sources to water systems. In rare cases, disease transmission has been recorded in some patients in which men-to-men sexual practices were preferred.

The life cycle of E. histolytica starts through ingestion of infectious cysts, which are non-dividing, quadri-nucleated structures surrounded …


Ocular Symptoms Assessment Of Covid-19: A Cross-Sectional Study, Wimolwan Tangpagasit, Sasivarin Luangpitakchumpol, Kritrath Panittaveekul Aug 2022

Ocular Symptoms Assessment Of Covid-19: A Cross-Sectional Study, Wimolwan Tangpagasit, Sasivarin Luangpitakchumpol, Kritrath Panittaveekul

Asian Medical Journal and Alternative Medicine

Introduction: The coronavirus disease 2019 (COVID-19) is an emerging lower respiratory tract infectious disease, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

Objectives: This research was purposed to assess the clinical manifestations of COVID-19 infection and the characteristics of ocular involvement.

Methods: This study is a cross-sectional quantitative study, an online questionnaire was performed on RT-PCR positive COVID-19 patients in Thailand.

Results: A total of 168 COVID-19 patients (32.3% male and 67.7% female) were enrolled in the study and completed an online questionnaire. The mean age of the patients was 39.14 ±12.7 years (ranging from 18 to 72 years). …


Real-Life Covid-19 Vaccine Effectiveness And Risk Factors Of Covid-19 Infection During Omicron Variant Epidemic In Thailand, Paskorn Sritipsukho, Thana Khawcharoenporn, Pichaya Tantiyavarong, Boonying Siribumrungwong, Pansachee Damronglerd, Nuntra Suwantarat, Araya Satdhabudha, Chanapai Chaiyakulsil, Phakatip Sinlapamongkolkul, Auchara Tangsathapornpong, Pornumpa Bunjoungmanee Aug 2022

Real-Life Covid-19 Vaccine Effectiveness And Risk Factors Of Covid-19 Infection During Omicron Variant Epidemic In Thailand, Paskorn Sritipsukho, Thana Khawcharoenporn, Pichaya Tantiyavarong, Boonying Siribumrungwong, Pansachee Damronglerd, Nuntra Suwantarat, Araya Satdhabudha, Chanapai Chaiyakulsil, Phakatip Sinlapamongkolkul, Auchara Tangsathapornpong, Pornumpa Bunjoungmanee

Asian Medical Journal and Alternative Medicine

Introduction: Data of real-life vaccine effectiveness (VE) and risk factors of COVID-19 infection during Omicron variant epidemic in Thailand are limited.

Methods: A test-negative case-control design was conducted to assess the VE for each dose of vaccination during the omicron variant epidemic (1 Jan to 30 April 2022). Available vaccine regimensin Thailand mainly consisted of inactivated vaccine (CoronaVac, SV), viral vector vaccine (ChAdOx1,AZ), and mRNAvaccine (BNT162b2, PF and Spikevax, MDN). All patients under investigation (PUI), aged more than 5 years, presenting at Thammasat University (TU) hospital for nasopharyngeal real-time polymerase chain reaction (RT-PCR) testing were prospectively enrolled and followed-up for …


Are Kenyans Likely To Use Covid-19 Self-Testing Kits? Results From A Cross-Sectional Survey, Griffins Manguro, Sonjelle Shilton, Sharon Omenda, Patrica Owira, Deepshikha Batheja, Abhik Banerji, Sophie Chabeda, Marleen Temmerman, Walter Jako, Stanley Luchters Aug 2022

Are Kenyans Likely To Use Covid-19 Self-Testing Kits? Results From A Cross-Sectional Survey, Griffins Manguro, Sonjelle Shilton, Sharon Omenda, Patrica Owira, Deepshikha Batheja, Abhik Banerji, Sophie Chabeda, Marleen Temmerman, Walter Jako, Stanley Luchters

Obstetrics and Gynaecology, East Africa

Objectives: To understand the public’s perceptions around rapid SARS-CoV-2 antigen self-testing in Kenya, including the drivers of acceptability, willingness to pay, and adherence to hygiene and prevention recommendations following a positive self-test.

Methods: A household-based, cross-sectional survey, using a 35-item questionnaire, was conducted in Mombasa and Taita–Taveta counties, Kenya, during August 2021. Individuals aged ≥18 years were enrolled using a stratified sampling approach.

Results: There were 419 participants (mean age 35.7 years). A minority (10.5%) had ever tested for SARS-CoV-2. If SARS-CoV-2 self-testing were available, 39.9% and 41.5% would be likely and very likely, respectively, to use it. If unavailable …


Infection And Transmission Determinants Of Flea-Borne Rickettsioses, Hanna J. Laukaitis Aug 2022

Infection And Transmission Determinants Of Flea-Borne Rickettsioses, Hanna J. Laukaitis

Graduate Theses and Dissertations (2019 - present)

The genus Rickettsia is comprised of Gram-negative, obligate intracellular bacteria that are spread by hematophagous arthropods. Elucidating the factors conferring rickettsial virulence has perplexed investigators for decades, complicated by the lack of efficient genetic tools necessary to uncover rickettsial- and vector-specific factors contributing to persistence. The advent of transposon mutagenesis has enabled the field to make vast developments in uncovering novel rickettsial mechanisms utilized in various host backgrounds. Thus, the aim of this study was to generate Rickettsia felis transposon mutants and characterize novel phenotypes associated with genetic disruption in an arthropod background. Distribution of rickettsiae is reliant on the …


Ecological And Phenotypic Diversification After A Continental Invasion In Neotropical Freshwater Stingrays, Matthew Kolmann, Fernando Pl Marques, James C. Weaver, Mason N. Dean, Joao Pedro Fontenelle, Nathan R. Lovejoy Aug 2022

Ecological And Phenotypic Diversification After A Continental Invasion In Neotropical Freshwater Stingrays, Matthew Kolmann, Fernando Pl Marques, James C. Weaver, Mason N. Dean, Joao Pedro Fontenelle, Nathan R. Lovejoy

Faculty and Staff Scholarship

Habitat transitions are key potential explanations for why some lineages have diversified and others have not—from Anolis lizards to Darwin's finches. The ecological ramifications of marine-to-freshwater transitions for fishes suggest evolutionary contingency: some lineages maintain their ancestral niches in novel habitats (niche conservatism), whereas others alter their ecological role. However, few studies have considered phenotypic, ecological, and lineage diversification concurrently to explore this issue. Here, we investigated the macroevolutionary history of the taxonomically and ecologically diverse Neotropical freshwater river rays (subfamily Potamotrygoninae), which invaded and diversified in the Amazon and other South American rivers during the late Oligocene to early …


The Role Of Microbiota On Campylobacter Jejuni Colonization And Growth Performance In Broiler Chickens, Ayidh Almansour Aug 2022

The Role Of Microbiota On Campylobacter Jejuni Colonization And Growth Performance In Broiler Chickens, Ayidh Almansour

Graduate Theses and Dissertations

The successful poultry production at modern era comes from the vertical integratedindustrialization, which has fundamentally changed how animals have been living for millions of years. Antimicrobial growth promoters have been used to sustain the efficient industrialized animal production, driving antimicrobial overuse and resistance. Because of the increasing pressure from consumer’s concerns and government regulations, it is urgent to develop antimicrobial free alternatives as growth promoters in poultry production, but few effective antimicrobial alternatives are currently available. Campylobacter jejuni is one of the worldwide prevalent foodborne bacterial pathogens mainly transmitted from poultry. However, few mechanisms are available on why C. jejuni …