Digital Commons Network^™

Virtual Global Health In Graduate Medical Education: A Systematic Review, Lisa Umphrey, Nora Lenhard, Suet Kam Lam, Nathaniel E Hayward, Shaina Hecht, Priya Agrawal, Amy Chambliss, Jessica Evert, Heather Haq, Stephanie M Lauden, George Paasi, Mary Schleicher, Megan Song Mchenry

Faculty, Staff and Students Publications

OBJECTIVES: To synthesize recent virtual global health education activities for graduate medical trainees, document gaps in the literature, suggest future study, and inform best practice recommendations for global health educators.

METHODS: We systematically reviewed articles published on virtual global health education activities from 2012-2021 by searching MEDLINE, EMBASE, Cochrane Library, ERIC, Scopus, Web of Science, and ProQuest Dissertations & Theses A&I. We performed bibliography review and search of conference and organization websites. We included articles about primarily virtual activities targeting for health professional trainees. We collected and qualitatively analyzed descriptive data about activity type, evaluation, audience, and drivers or barriers. …

Optimal Urine Culture Diagnostic Stewardship Practice- Results From An Expert Modified-Delphi Procedure, Kimberly C Claeys, Stephen Y Liang, Et Al.

2020-Current year OA Pubs

BACKGROUND: Urine cultures are nonspecific and often lead to misdiagnosis of urinary tract infection and unnecessary antibiotics. Diagnostic stewardship is a set of procedures that modifies test ordering, processing, and reporting in order to optimize diagnosis and downstream treatment. In this study, we aimed to develop expert guidance on best practices for urine culture diagnostic stewardship.

METHODS: A RAND-modified Delphi approach with a multidisciplinary expert panel was used to ascertain diagnostic stewardship best practices. Clinical questions to guide recommendations were grouped into three thematic areas (ordering, processing, reporting) in practice settings of emergency department, inpatient, ambulatory, and long-term care. Fifteen …

Why Not Both Nature And Nurture: Using Behavioral Genetic Markers As Sentencing Factors, Seely Kaufmann

Richmond Journal of Law & Technology

On the evening of July 1, 2013, Amos Wells was upset that his pregnant girlfriend, Chanice Reed, would not answer his calls. He then drove to where she, her mother Annette, and ten-year-old brother Eddie, lived. After arguing with Chanice and yelling at the top of his voice in a “bone-chilling scream,” Wells retrieved a handgun from his Chevrolet Tahoe parked in front of the house, and shot Chanice in the front yard as she screamed, “No, no, no.” Her mother then tried to bat the gun away before he shot her too. Further shots were heard before Wells finally …

Rediscovery Of The Living Law In Natural Disaster Mitigation In Majene Regency, West Sulawesi Province, Indonesia, Rahmat Bakri, Sulbadana Sulbadana, Saharuddin Saharuddin3, Asria Wayuni Ahmad

Indonesia Law Review

The living law and state law are two schools of law that are always dialectical in the development of law in a country. If the two can be synergized properly, then the legal function will run effectively and the legal objectives will be achieved. In the context of natural disaster mitigation in Indonesia, the synergy between the living law and state law can be proposed as a solution to streamline the various existing laws. This study aims to reidentify natural disaster mitigation models a previous result of the collective creativity of the people of Totolisi Sendana Village, Majene Regency, West …

Re-Examining Rotavirus Innate Immune Evasion: Potential Applications Of The Reverse Genetics System, Avan Antia, Amanda N Pinski, Siyuan Ding

2020-Current year OA Pubs

Rotaviruses represent one of the most successful pathogens in the world, with high infectivity and efficient transmission between the young of many animal species, including humans. To overcome host defenses, rotaviruses have evolved a plethora of strategies to effectively evade the innate immune response, establish initial infection in the small intestine, produce progeny, and shed into the environment. Previously, studying the roles and relative contributions of specific rotaviral factors in innate immune evasion had been challenging without a plasmid-only reverse genetics system. Although still in its infancy, current reverse genetics technology will help address important research questions regarding rotavirus innate …

Qualitative Evaluation Of Antibiotics Use With Gyssens Method In Sepsis Patients At Fatmawati Central General Hospital Jakarta, Mas Masyrifah, Retnosari Andrajati, Linda Triana Yudhorini

Pharmaceutical Sciences and Research

Sepsis still becomes a major health problem worldwide, with a fairly high mortality rate ranging from 20 to 50%. Antibiotic therapy with rational use can reduce the mortality rate. In contrast, the irrational use of antibiotic therapy will increase the occurrence of resistance, which impacts the increase of morbidity, mortality, and health costs. The objective of this study was to evaluate the quality in the use of antibiotics using the Gyssens method in patients with sepsis. This study was an observational study with a cross-sectional method conducted at Fatmawati Central General Hospital Jakarta from January to December 2020. The research …

Discovery Of Sars-Cov-2 Rna-Dependent-Rna-Polymerase (Rdrp) Inhibitor From Sambiloto (Andrographis Paniculata) Based On Molecular Docking And Admet Prediction Approach, Dina Ahsana, Rizki Rahmadi Pratama, Alfisyahriatunnida Meily, Andika Andika

Pharmaceutical Sciences and Research

The rapid spread of the coronavirus disease 2019 (COVID-19) has led to the development of therapeutic inhibitor drug of SARS-CoV-2, which can inhibit the viral enzyme RNA-dependent-RNA-polymerase (RdRp), thereby preventing the replication, transcription, and synthesis of RNA virus in the host cells. Previous in-vitro studies revealed that Andrographis paniculata has the potential to inhibit the virus. Therefore, this study aims to isolate the specific compounds of Andrographis paniculata, which play a role in inhibiting SARS-CoV-2 RdRp using molecular docking. A total of 19 compounds were identified in previous literature studies, while remdesivir and favipiravir were used as the positive …

Covid-19 Newsletter (Vol. 134), Center For Disaster Medicine, New York Medical College

COVID-19 Newsletter

No abstract provided.

Increased Anxiety From Fear Of Omicron In China As Compared To North America And Western Europe: A Cross-Sectional Kendall's Tau-B Analysis Using The Generalized Anxiety Disorder 7-Item Questionnaire, Dan Shan, Chang Liu, Shaoyang Li, Yuandian Zheng

Student Publications

Background: Policies dealing with the Coronavirus Disease 2019 (COVID-19) pandemic vary across the globe, the different governmental responses then affect the public perception of COVID-19. Many unofficial Chinese media outlets frequently spread misinformation about COVID-19 and exaggerated reports of rare sequelae of Omicron for monetization and attention seeking, leading to panics in the Chinese public. In comparison the attitudes toward Omicron in other countries around the world, especially in North America and Western Europe have shifted to a more relaxed stance.

Objective: This article primarily aims to investigate the association between Chinese people’s attitudes toward the potential after-effects of Omicron …

A Multitrait Locus Regulates Sarbecovirus Pathogenesis, Alexandra Schäfer, Emma S Winkler, Michael S Diamond, Et Al

2020-Current year OA Pubs

Infectious diseases have shaped the human population genetic structure, and genetic variation influences the susceptibility to many viral diseases. However, a variety of challenges have made the implementation of traditional human Genome-wide Association Studies (GWAS) approaches to study these infectious outcomes challenging. In contrast, mouse models of infectious diseases provide an experimental control and precision, which facilitates analyses and mechanistic studies of the role of genetic variation on infection. Here we use a genetic mapping cross between two distinct Collaborative Cross mouse strains with respect to severe acute respiratory syndrome coronavirus (SARS-CoV) disease outcomes. We find several loci control differential …

Towards Public Vaccination Data Resilience During Natural Disaster Using Blockchain-Based Decentralized Application, Riri Fitri Sari, Mokhammad Rizqi Herdiawan, Muhammad Hamzah, Muhammad Aljundi, Jauzak Hussaini Windiatmaja

Smart City

This paper presents a platform development plan for a public vaccination decentralized data base based on Blockchain technology. Vaccination is a medical practice that allows a human body to produce a specific antibody as a means of developing a preventive measure and reducing the risk of contracting a particular disease. Systematic vaccination data recording is an utmost important system that is required particularly during the Covid-19 pandemic. The recording mechanism should utilize the state-of-the-art information and communication technology (ICT). For faster vaccination data recording, it is common to use digital technology, making the health care process faster thus decreasing time …

The Rider (2022-08-29), Verilu Infante

The Rider Archives

Vol.8 No.1

Editor's Note, Anucha Apisarnthanarak

Asian Medical Journal and Alternative Medicine

No abstract provided.

Travel Medicine, Somchai Bovornkitti

Asian Medical Journal and Alternative Medicine

No abstract provided.

Current Landscape Of Uveitis Specialists In The United States, Edmund Tsui, Eric L. Crowell, Sapna Gangaputra, Kareem Moussa, Jessica G. Shantha, Alexander J. Shusko, Ian A. Thompson, Derek C. Pham, Nicholas J. Jackson, Arthi G. Venkat

Journal of Academic Ophthalmology

Abstract

Purpose This study characterizes the current landscape of uveitis specialists and their practice settings in the United States.

Methods An anonymous Internet-based survey with questions pertaining to training history and practice characteristics was distributed via REDCap to the American Uveitis Society and Young Uveitis Specialists listservs.

Results Forty-eight uveitis specialists in the United States responded to the survey out of 174 uveitis specialists that identify as practicing in the United States. Twenty-five of 48 respondents (52%) completed an additional fellowship. These additional fellowships ranged from surgical retina (12/25, 48%), cornea (8/25, 32%), and medical retina (4/25, 16%). Two-thirds of …

Mortality Rate And Associated Factors In Critically Ill Intubated Patients With Coronavirus Disease 2019 (Covid-19) At Pranangklao Hospital, Natthika Yurakate, Muthita Phanasathit

Asian Medical Journal and Alternative Medicine

Introduction: In the epidemic wave of the ongoing coronavirus disease 2019 (COVID-19) pandemic in April 2021. This study aimed to explore the 30-day mortality rate and its associated factors and anesthetic practice in critically ill COVID-19 patients who received intubation.
Methods: This retrospective cohort study was collected data from medical records in critically ill COVID-19 patients who received intubation and admitted to Pranangklao Hospital (PNKH) from April 1 to June 30, 2021.
Results: A total of 73 patients were admitted and intubated with the median age was 65 years (IQR = 18), 43 (58.9%) were male, 37 (50.7%) were body …

Occupational Health And Safety Trainees Reflect On Their Education And Future Careers During Covid-19., Jennifer Marshall Phd, Mph, Cph, Vidya Chandran Mba, Mph, Cph, Bds, Davies Toluhi Mbchb, Mph, Cph, Karen D. Liller Phd, Mph, Cph, Saloni Mehra Mph, Cph, Candace Burns Phd, Ms, Aprn, Faaohn

Florida Public Health Review

Background: The National Institute for Occupational Safety and Health (NIOSH) funded Education and Research Centers (ERCs), located at 18 universities, with the mission to train occupational safety and health (OSH) leaders. The Florida Sunshine ERC has trained hundreds of students since its inception in 1997 through seven programs that collaboratively foster interdisciplinary education and applied research and practice. The COVID-19 pandemic has presented practical challenges for educators, students, and trainees, forcing institutions to move to remote learning. The pandemic also magnifies the importance of public health and OSH.

Purpose: This evaluation elicited feedback from ERC trainees early in the …

Pharmacist-Administered Influenza Vaccination In Children And Corresponding Regulations, Dana M. Gates, A. Cohen, Kelly Orr, Aisling R. Caffrey

Pharmacy Practice and Clinical Research Faculty Publications

In our retrospective cohort study, we evaluated trends in pharmacist-administered pediatric influenza vaccination rates in the United States and corresponding state-level pharmacist pediatric vaccination authorization models, including minimum age requirements, vaccination protocols, and/or prescription requirements. An administrative health claims database was used to capture influenza vaccinations in children less than 18 years old with 1 year of continuous enrollment and joinpoint regression was used to assess trends. Of the 3,937,376 pediatric influenza vaccinations identified over the study period, only 3.2% were pharmacist-administered (87.7% pediatrician offices, 2.3% convenience care clinics, 0.8% emergency care, and 6.0% other locations). Pharmacist-administered pediatric influenza vaccination …

Capg Is Required For Ebola Virus Infection By Controlling Virus Egress From Infected Cells, Hiroyuki Mori, James P Connell, Callie J Donahue, Ruthmabel Boytz, Yen Thi Kim Nguyen, Daisy W Leung, Douglas J Lacount, Robert A Davey

2020-Current year OA Pubs

The replication of Ebola virus (EBOV) is dependent upon actin functionality, especially at cell entry through macropinocytosis and at release of virus from cells. Previously, major actin-regulatory factors involved in actin nucleation, such as Rac1 and Arp2/3, were shown important in both steps. However, downstream of nucleation, many other cell factors are needed to control actin dynamics. How these regulate EBOV infection remains largely unclear. Here, we identified the actin-regulating protein, CAPG, as important for EBOV replication. Notably, knockdown of CAPG specifically inhibited viral infectivity and yield of infectious particles. Cell-based mechanistic analysis revealed a requirement of CAPG for virus …

Divergent Neural And Endocrine Responses In Wild-Caught And Laboratory-Bred Rattus Norvegicus, Joanna Jacob, Sally Watanabe, Jonathan Richardson, Nick Gonzales, Emily Ploppert, Garet Lahvis, Aaron Shiels, Sadie Wenger, Kelly Saverino, Janhavi Bhalerao, Brendan Crockett, Erin Burns, Olivia Harding, Krista Fischer-Stenger, Kelly Lambert

United States Department of Agriculture Wildlife Services: Staff Publications

Although rodents have represented the most intensely studied animals in neurobiological investigations for more than a century, few studies have systematically compared neural and endocrine differences between wild rodents in their natural habitats and laboratory strains raised in traditional laboratory environments. In the current study, male and female Rattus norvegicus rats were trapped in an urban setting and compared to weight-and sex-matched conspecifics living in standard laboratory housing conditions. Brains were extracted for neural assessments and fecal boli were collected for endocrine [corticosterone and dehydroepiandrosterone (DHEA)] assays. Additionally, given their role in immune and stress functions, spleen and adrenal weights …

Novel Epidemics: Contagion And Metaphor In Us Literature, Maxwell Clement Cassity

Dissertations - ALL

Metaphors of epidemic and contagion have played a powerful role in shaping American identity by using disease to symbolically mark out certain raced and classed populations as outsiders to the social body. In the twentieth century, epidemics and epidemiological reading came to dominate not only the fields of science, but also literary and cultural production and its critical lenses. “Novel Epidemics” examines how American novelists William Faulkner, Ishmael Reed, and Helena María Viramontes used epidemic as a fictional framework for examining and critiquing the ways that the US social body was imagined, constructed, and reinforced through an epidemiological lens. Using …

Protection Against Contagion In Complex Networks, Pegah Hozhabrierdi

Dissertations - ALL

In real-world complex networks, harmful spreads, commonly known as contagions, are common and can potentially lead to catastrophic events if uncontrolled. Some examples include pandemics, network attacks on crucial infrastructure systems, and the propagation of misinformation or radical ideas. Thus, it is critical to study the protective measures that inhibit or eliminate contagion in these networks. This is known as the network protection problem.

The network protection problem investigates the most efficient graph manipulations (e.g., node and/or edge removal or addition) to protect a certain set of nodes known as critical nodes. There are two types of critical nodes: (1) …

Vaccines For Adults: Here Is What You Need To Know, Anna Jones

Browse All News

No abstract provided.

Controlling Multiple Covid-19 Epidemic Waves: An Insight From A Multi-Scale Model Linking The Behaviour Change Dynamics To The Disease Transmission Dynamics, Biao Tang, Weike Zhou, Xia Wang, Hulin Wu, Yanni Xiao

Faculty, Staff and Student Publications

COVID-19 epidemics exhibited multiple waves regionally and globally since 2020. It is important to understand the insight and underlying mechanisms of the multiple waves of COVID-19 epidemics in order to design more efficient non-pharmaceutical interventions (NPIs) and vaccination strategies to prevent future waves. We propose a multi-scale model by linking the behaviour change dynamics to the disease transmission dynamics to investigate the effect of behaviour dynamics on COVID-19 epidemics using game theory. The proposed multi-scale models are calibrated and key parameters related to disease transmission dynamics and behavioural dynamics with/without vaccination are estimated based on COVID-19 epidemic data (daily reported …

A Qualitative Assessment Of The Essential Health And Nutrition Service Delivery In The Context Of Covid-19 In Bangladesh: The Perspective Of Divisional Directors, Pablo Gaitán-Rossi, Mireya Vilar-Compte, Valeria Cruz-Villalba, Nazme Sabina, Manuela Villar-Uribe

Department of Public Health Scholarship and Creative Works

Bangladesh suffered disruptions in the utilization of essential health and nutrition services (EHNS) during the COVID-19 pandemic. The magnitude of the pandemic has been documented, but little is known from the perspectives of health administrators. A rapid qualitative assessment of division-level capacity identified successes and bottlenecks in providing EHNS- and COVID-19-related services during the first months of the pandemic in Bangladesh. Semi-structured interviews were held with the Health and Family Planning Divisional Directors of the Ministry of Health and Family Welfare. The Primary Health Care System Framework guided the content analysis, focusing on (i) service delivery, (ii) communication and community …

Female Genital Tuberculosis Among Infertile Women And Its Contributions To Primary And Secondary Infertility, Musa Ae Ahmed, Abdullah Aa Mohammed, Abiodun O. Ilesanmi, Christopher O. Aimakhu, Amel O. Bakhiet, Suad Bm Hamad

Sultan Qaboos University Medical Journal

Female genital tuberculosis (FGTB) is a widespread infectious disease among young women. This meta-analysis aimed to investigate the prevalence of FGTB among infertile women and its contribution to primary and secondary infertility. PubMed, MEDLINE®, WorldCat, The Lens, direct Google search, Google Scholar and ResearchGate were searched from 1971 to July 17, 2021 using the following terms: “prevalence”, “epidemiology”, “urogenital tuberculosis”, “FGTB”, “infertile women”, “infertility complaints” and “FGTB testing methods”. Data were extracted and a meta-analysis was performed. A total of 42 studies were selected with a total of 30,918 infertile women. Of these, the pooled prevalence of FGTB was 20% …

Genitourinary Symptoms Associated With Chlamydia Trachomatis And Neisseria Gonorrhoeae Infections In A Tertiary Care Hospital In Oman, Zakariya Al-Muharrmi, Richard Lau, Ahad Al-Balushi, Alyazi Al-Saadi, Zeyana Al-Habsi, Ali Elgalib, Samir Shah, Maha Al-Fouri, Bader Al-Rawahi, Seif Al-Abri

Sultan Qaboos University Medical Journal

Objectives: This study aimed to determine the pattern of clinical presentations associated with Chlamydia trachomatis and Neisseria gonorrhoeae infections. Methods: A retrospective cohort study was conducted between 2015 and 2020 and included patients attending Sultan Qaboos University Hospital, Muscat, Oman, who were tested for these infections using nucleic acid amplification. Results: A total of 408 women and 89 men were included. A total of 11 infections were identified in women (n = 11, 2.7%) and 14 in men (n = 14, 15.7%). Chlamydia accounted for almost all infections in women (n = 10, 90.9%), commonly presenting with lower abdominal pain …

Post Covid-19 Guillain-Barré-Syndrome (Gbs), Mohammed M. Al-Zadjali, Emaad Al Shibli, Mohammed Al Maskari, Arunodaya R. Gujjar, Abdullah Al Asmi

Sultan Qaboos University Medical Journal

Guillain-Barré-Syndrome (GBS) is one of the reported neurological manifestations linked to a severe acute respiratory syndrome caused by coronavirus 2 (SARS-CoV-2)(COVID-19). We are presenting a case of a 72-years-old male patient who attended Sultan Qaboos University Hospital with a history of progressive bilateral limbs weakness and numbness. After exclusion of other possible causes, a diagnosis of GBS induced by COVID-19 was made. He received Intravenous Immunoglobulin (IVIG) 0.4g/kg/day for 5 days. This diagnosis is in line with a rare complication of COVID-19. This case highlights the characteristics and the course of GBS following COVID-19 infection. Further studies are needed to …

Years Of Life Lost Associated With Covid-19 Deaths In The Usa During The First 2 Years Of The Pandemic, Troy Quast, Ross Andel, Sean Gregory, Eric A Storch

Center for Medical Ethics and Health Policy Staff Publications

Background: Prior estimates of the years of life lost (YLLs) in the USA associated with coronavirus disease 2019 (COVID-19) were 1.2 million through 11 July 2020 and 3.9 million through 31 January 2021 (which roughly coincides with the first full year of the pandemic). The aim of this study is to update YLL estimates through the first 2 years of the pandemic.

Methods: We employed data regarding COVID-19 deaths through 5 February 2022 by jurisdiction, gender and age group. We used actuarial life expectancy tables by gender and age to estimate YLLs.

Results: We estimated roughly 9.7 million YLLs due …

Women And Land Snails Consumption In The Southwest Region Of Cameroon, Forka Leypey Mathew Fomine

Journal of International Women's Studies

Both marine and terrestrial species of snails are consumed in most countries worldwide, including Southwest Cameroon where it is an age-old practice among various ethnic groups. Before the introduction of snail farming in the Southwest Region of Cameroon in the 1990s, all the residents who ate snails acquired them through gathering.

There is significant internal variation in the history of land snail consumption among four ethnic groups: the Banyang, Mbo, Balung, and Bakweri. The long history of land snail consumption among the Banyang and Mbo can be attributed to their geographical proximity to the eastern region of Nigeria, where the …